Digital Commons Network^™

A Structured, Journal-Led Peer-Review Mentoring Program Enhances Peer Review Training, Roy E Strowd

Faculty, Staff and Students Publications

BACKGROUND: Peer review is essential to the advancement of knowledge. However, training on how to conduct peer review is limited, unorganized, and not well studied. Thus, we sought to determine if a structured mentored peer-review program improved peer review training as measured by multiple quantitative and qualitative assessments.

METHODS: This pre-post intervention study enrolled 55 mentees across 5 cohorts from 2020 to 2023. Each cohort completed pre-program evaluations, participated in 2 mentored reviews, and completed post-program evaluations over 6 months. Mentors and mentees completed pre-program demographic and review experience questionnaires. Outcome measures included (1) total and sub-scores on the modified …

Antioxidant Responses And Phytochemical Accumulation In Raphanus Species Sprouts Through Elicitors And Predictive Models Under High Temperature Stress, José Becerra, Nelson Zapata, María Dolores López-Belchí

Faculty, Staff and Students Publications

Crop production is being impacted by higher temperatures, which can decrease food yield and pose a threat to human nutrition. In the current study, edible and wild radish sprouts were exposed to elevated growth temperatures along with the exogenous application of various elicitors to activate defense mechanisms. Developmental traits, oxidative damage, glucosinolate and anthocyanin content, and antioxidant capacity were evaluated alongside the development of a predictive model. A combination of four elicitors (citric acid, methyl jasmonate—MeJa, chitosan, and K2SO4) and high temperatures were applied. The accumulation of bioactives was significantly enhanced through the application of two elicitors, K2SO4 and methyl …

Isoform Alterations In The Ubiquitination Machinery Impacting Gastrointestinal Malignancies, Srimathi Kasturirangan, Derek Nancarrow, Ayush Shah, Kiran Lagisetty, Theodore Lawrence, David Beer, Dipankar Ray

Department of Medicine Faculty Papers

The advancement of RNAseq and isoform-specific expression platforms has led to the understanding that isoform changes can alter molecular signaling to promote tumorigenesis. An active area in cancer research is uncovering the roles of ubiquitination on spliceosome assembly contributing to transcript diversity and expression of alternative isoforms. However, the effects of isoform changes on functionality of ubiquitination machineries (E1, E2, E3, E4, and deubiquitinating (DUB) enzymes) influencing onco- and tumor suppressor protein stabilities is currently understudied. Characterizing these changes could be instrumental in improving cancer outcomes via the identification of novel biomarkers and targetable signaling pathways. In this review, we …

Observation On Efficacy And Underlying Mechanism Of Cheek Acupuncture On Ovulation Induction For Infertile Women With Pcos: Case Series, Xi Luo

Faculty, Staff and Student Publications

RATIONALE: Polycystic ovary syndrome (PCOS) is the most common reproductive endocrine disorder among women of childbearing age and is the primary cause of anovulatory infertility, accounting for 70% to 80% of cases. Ovulation induction is the main treatment approach for infertile patients with PCOS. Commonly utilized medications for this purpose are clomiphene citrate (CC) and letrozole (LE). Clomiphene citrate administration results in an ovulation rate ranging from 60% to 85%, while the pregnancy rate is limited to 35% to 40%, and a further reduction is observed in live birth rates. Letrozole demonstrates a slightly higher pregnancy rate and live birth …

The Acceptance And Use Of Digital Technologies For Self-Reporting Medication Safety Events After Care Transitions To Home In Patients With Cancer: Survey Study, Sarah T Hawley, Milisa Manojlovich, John C Krauss, Yang Gong

Faculty, Staff and Student Publications

BACKGROUND: Actively engaging patients with cancer and their families in monitoring and reporting medication safety events during care transitions is indispensable for achieving optimal patient safety outcomes. However, existing patient self-reporting systems often cannot address patients' various experiences and concerns regarding medication safety over time. In addition, these systems are usually not designed for patients' just-in-time reporting. There is a significant knowledge gap in understanding the nature, scope, and causes of medication safety events after patients' transition back home because of a lack of patient engagement in self-monitoring and reporting of safety events. The challenges for patients with cancer in …

Co‐Producing Ethics Guidelines Together With People With Learning Disabilities, M Bottomley, J Bradley, L Clark, Nk Hayden, Et Al

Peninsula Medical School

Background We are a research team of clinical, academic and advocacy-based researchers with and without learning disabilities, working on the Humanising Healthcare (for people with learning disabilities) project. The project is dedicated to finding and sharing healthcare practices that enhance the lives of people with learning disabilities. As part of our ethics applications to access National Health Service study sites for fieldwork, we worked together to write guiding principles for co-producing research ethics with researchers with learning disabilities. In this paper, we introduce these Participatory Ethics Good Practice Guidelines and reflect on our collaboration. Methods We reflect on developing the …

Highly Efficient Dopamine Sensing With A Carbon Nanotube-Encapsulated Metal Chalcogenide Nanostructure, Harish Singh, Jiandong Wu, Kurt A.L. Lagemann, Manashi Nath

Chemical and Biochemical Engineering Faculty Research & Creative Works

Carbon nanotube-encapsulated nickel selenide composite nanostructures were used as nonenzymatic electrochemical sensors for dopamine detection. These composite nanostructures were synthesized through a simple, one-step, and environmentally friendly chemical vapor deposition method, wherein the CNTs were formed in situ from pyrolysis of a carbon-rich metallo-organic precursor. The composition and morphology of these hybrid NiSe2-filled carbon nanostructures were confirmed by powder X-ray diffraction, Raman, X-ray photoelectron spectroscopy, and high-resolution transmission electron microscopy images. Electrochemical tests demonstrated that the as-synthesized hybrid nanostructures exhibited outstanding electrocatalytic performance toward dopamine oxidation, with a high sensitivity of 19.62 μA μM-1 cm-2, low detection limit, broad linear …

A Deep Learning Convolutional Neural Network For Antenna Near-Field Prediction And Surrogate Modeling, Md Rayhan Khan, Constantinos L. Zekios, Shubhendu Bhardwaj, Stavros V. Georgakopoulos

Department of Electrical and Computer Engineering: Faculty Publications

This study investigates the use of deep learning techniques for building a generalized surrogate model that can accurately and very efficiently predict antenna performance parameters. Notably, we focus on applications where a substantial amount of simulation time is required and prior data is available for deep learning use. Specifically, for these applications, we introduce deep learning models that efficiently and reliably model the near-field of the antenna. These models, in turn, accurately predict far-field properties and essential antenna metrics, such as the reflection coefficient. To demonstrate the efficiency of our method, the widely used rectangular patch antenna is considered, encompassing …

Identification Of Novel Small Molecule Inhibitors Of Twin Arginine Translocation (Tat) Pathway And Their Effect On The Control Of Campylobacter Jejuni In Chickens, Loïc Deblais, Mary Drozd, Anand Kumar, Janet Antwi, James Fuchs, Rahul Khupse, Yosra A. Helmy, Gireesh Rajashekara

School of Veterinary and Biomedical Sciences: Faculty Publications

Introduction: Control of Campylobacter from farm to fork is challenging due to the frequent emergence of antimicrobial-resistant isolates. Furthermore, poultry production systems are known reservoirs of Campylobacter. The twinarginine translocation (Tat) pathway is a crucial bacterial secretion system that allows Campylobacter to colonize the host intestinal tract by using formate as the main source of energy. However, Tat pathway is also a major contributing factor for resistance to copper sulfate (CuSO₄).

Methods: Since mammals and chickens do not have proteins or receptors that are homologous to bacterial Tat proteins, identification of small molecule (SM) inhibitors …

Feature Engineering And Supervised Machine Learning To Forecast Biogas Production During Municipal Anaerobic Co-Digestion, Hunter W. Schroer, Craig L. Just

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Municipalities with excess anaerobic digestion capacity accept offsite wastes for co-digestion to meet sustainability goals and create more biogas. Despite the benefits inherent to co-digestion, the temporal and compositional heterogeneity of external waste streams creates operational challenges that lead to upsets or conservative co-digestion. Given the complex microbial bioprocesses occurring during anaerobic digestion, prediction and modeling of the outcomes can be challenging, and machine learning has the potential to improve understanding and control of co-digestion processes. Biogas flows are a surrogate for process health, and here, we predicted biogas production from historical data collected by a water resource recovery facility …

Yearly Population Data At Census Tract Level Revealed That More People Are Now Living In Highly Fire-Prone Zones In California, Usa, Slade Lazeweski, Shenyue Jia, Jessica E. Viner, Wesley Ho, Brian Hoover, Seung Hee Kim, Menas C. Kafatos

Institute for ECHO Articles and Research

In California (CA), the wildland-urban interface (WUI) faces escalating challenges due to surging population and real estate development. This study evaluates communities along CA's WUI that have witnessed substantial population growth from 2010 to 2021, utilizing demographic data and the 2020 WUI boundaries by the University of Wisconsin-Madison SILVIS Lab. Employing the Mann-Kendall test, we analyze yearly population trends for each census tract along the CA WUI and assess their significance. House ownership, affordability, and wildfire risk are examined as potential drivers of this demographic shift. Our findings indicate that 12.7% of CA's total population now resides in census tracts …

Dean Crowell Shares Lessons From His Career In New York Law Journal, Ariel Dvorkin

NYLS Community News

No abstract provided.

Comparison Study Of Endoscopic-Guided Versus Electromyography-Guided Botulinum Toxin Injection Treatments In Adductor Spasmodic Dysphonia, Manintorn Praditthum, Premsuda Sombuntham

Chulalongkorn Medical Journal

Background: Electromyography (EMG)-guided botulinum injection is recommended in clinical practice guideline for spasmodic dysphonia. However, other alternative techniques have been practiced in absence of EMG machine. Comparison of techniques is limited in the literatures.

Objective: This pilot study aims to compare the effectiveness of treatment between the EMG-guided technique and the endoscopic-guided technique in adductor spasmodic dysphonia.

Method: Five patients who were diagnosed with Adductor spasmodic dysphonia (AdSD) were enrolled and then randomized into 2 groups. Patient data (before and after treatment) were collected. The outcome measurement included voice analysis, voice handicap index (VHI), duration aspiration, duration of breathiness, mean …

Exonic Variants Of Gpihbp1 Gene In Thai Subjects With Severe Hypertriglyceridemia, Wanee Plengpanich

Chulalongkorn Medical Journal

Background: Hypertriglyceridemia (HTG) is one of the risk factors for cardiovascular disease and acute pancreatitis. It is associated with genetic variations in various genes involved in triglyceride metabolism. Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 (GPIHBP1) encodes a membrane protein involved in an intravascular triglyceride hydrolysis. Objective: The purpose of this study was to examine the genetic variants in the exons of GPIHBP1 gene in Thai subjects with severe HTG. Methods: All 4 exons of the GPIHBP1 gene were sequenced in 101 Thai subjects with severe HTG. All subjects had triglyceride levels e” 10 mmol/L or 886 mg/dL. Subjects with normolipidemia (n …

Association Of Pnpla3, Tm6sf2 And Hsd17b13 Variants With Nafld Risk In Hiv And Non-Hiv Individuals, Varis Ruamviboonsuk

Chulalongkorn Medical Journal

Background: Non-alcoholic fatty liver disease (NAFLD) has multiple risk factors, including genetic risk factors. Patients with certain genetic variants are more susceptible to the disease. People living with human immunodeficiency virus (PLWH) have higher prevalence of NAFLD compared to those without human immunodeficiency virus (HIV) infection. However, the evidence on genetic factors in PLWH with NAFLD is limited. Objectives: This study aimed to investigate whether carriers of PNPLA3 rs738409, TM6SF2 rs58542926, and HSD17B13 rs6834314 had association with the risk of NAFLD, and whether PLWH with NAFLD also had similar genetic risk factors as those with NAFLD alone. Methods: These single …

Attitudes Toward End-Of-Life Care And Advance Directives: A Prospective Survey In A Family Medicine Clinic, Bangkok, Thailand, Basmon Manomaipiboon

Chulalongkorn Medical Journal

Background: Advance directives (ADs) have long been legalized and advocated, still few patients complete ADs in Thailand. In our setting, advance directive information will be provided to interested patients and palliative care patients. Objectives: This study examined the attitude toward end-of-life care and ADs, the prevalence of ADs completion and identified the factors associated with advance care planning among patients who attended a family medicine clinic, Faculty of Medicine, Vajira Hospital, Navamindhradhiraj university, Bangkok, Thailand. Methods: A total of 300 subjects completed a self-administered structured questionnaire, including sociodemographic factors, individuals’ health status, healthcare experiences, and other factors influencing advance care …

Factors Related To Positive Airway Pressure Adherence In Patients With Obstructive Sleep Apnea At King Chulalongkorn Memorial Hospital, Puntarik Srisawart

Chulalongkorn Medical Journal

Background: Positive airway pressure (PAPs) is a standard and efficacious treatment for obstructive sleep apnea (OSA). Poor adherence could lead to impaired daytime performance, increasing risk of traffic accidents, hypertension, cardiovascular events, and neuropsychological disturbances. Previous studies reported rates and factors influencing PAPs adherence, but the data in Thailand was still lacking.

Objectives: To investigate the rate of PAPs adherence, the prevalence of depressive and anxiety symptoms, and the factors associated with PAPs adherence among patients with OSA.

Methods: This is a cross-sectional descriptive study that was conducted during June 2021 to September 2022. The data was collected from patients …

Pulmonary Rehabilitation For Critically Ill Elderly Patients With Covid-19 In Thailand: A Report Of Two Cases, Thitapa Issaragraisin, Jirapa Champaiboon

Chulalongkorn Medical Journal

The vast majority of patients exposed to coronavirus (COVID-19) were likely to face complications during their recovery from coronavirus. The first case was an old Thai woman presented with severe COVID-19 pneumonia. The other was an old Thai man presented with COVID-19 with complications such as acute respiratory distress syndrome, hyperglycemia, thrombocytopenia, right tension pneumothorax with recurrent pneumothorax and monoparesis. These two cases presented the role of physical therapy for critically ill elderly patients with chest complications from COVID-19.

Resilience And Related Factors Among Volunteers Of Thai Red Cross Society At King Chulalongkorn Memorial Hospital, Kanyaphak Nakalekha

Chulalongkorn Medical Journal

Background: Volunteers of the Thai Red Cross Society have contributed valuable helps to the Thai Red Cross Society and King Chulalongkorn Memorial Hospital. However, there was still a lack of studies on mental health aspects in this group, especially positive psychological resources, i.e., resilience.

Objectives: To examine the levels of resilience quotient (RQ) and associated factors among volunteers of the Thai Red Cross Society at King Chulalongkorn Memorial Hospital.

Methods: We recruited 287 subjects who were currently working as volunteers of the Thai Red Cross Society during 2021 - 2022. The subjects were asked to complete five questionnaires including personal …

The Symptoms And Management Of Children With Attention-Deficit/Hyperactivity Disorder During Covid-19 Pandemic At The Child And Adolescent Psychiatry Clinic, King Chulalongkorn Memorial Hospital, Nuttorn Pityaratstian

Chulalongkorn Medical Journal

Background: The coronavirus disease 2019 (COVID-19) pandemic has caused abrupt changes in almost everybody’s life, particularly children. Children and adolescents with attention-deficit hyperactivity disorder (ADHD) have difficulties in many aspects in lives and may have worsening of the symptoms during the pandemic.

Objectives: This cross-sectional descriptive study aimed to investigate the changes of the ADHD symptoms and managements of children with ADHD during the first lockdown and after-lockdown period.

Methods: Parent-reported questionnaires i.e. the Swanson, Nolan, and Pelham Rating Scale-IV (SNAP-IV) and a demographic questionnaire, were applied to collect data from 109 children with ADHD aged between 4 -18 years …

Full Issue

The Thetean: A Student Journal for Scholarly Historical Writing

No abstract provided.

The Partisan Press Of Illinois: Motivation, Rhetoric, And Aggression In Hancock County Newspapers, 1839-1844, Elizabeth Prete Bryner

The Thetean: A Student Journal for Scholarly Historical Writing

Much has been written about the pohtical origins of the Mormon conflicts in Nauvoo, Illinois, between 1839 and 1844, but relatively little scholarship has analyzed the role of the partisan press in that conflict. George Gayler and other historians claim that· Mormon political activity ... must be singled out as the chief source of irritation between [ the Mormons] and the Illinois citizens." However, Gayler limits his investigation of the press mostly to the anti-Mormon newspapers, the Nauvoo Expositor and the Warsaw Signal. Governor Thomas Fords History cf Illinois describes the sordid political battle between the Whigs and the …

Children On The Mormon Trail, Jill Jacobsen Andros

The Thetean: A Student Journal for Scholarly Historical Writing

While reflecting on her experience crossing the plains in a Mormon handcart company at age nine, Agnes Caldwell, recalled:

"Although only tender years of age, I can yet close my eyes and see everything in panoramic precision before me-the ceaseless walking, walking, ever to remain in my memory. Many times I would become so tired and, childlike, would hang on the cart, only to be gently pushed away. Then I would throw myself by the side of the road and cry. Then realizing they were all passing me by, I would jump to my feet and make an extra run …

The Transformation Of Utah From A Colony Of Wall Street To A Colony Of Washington, Thomas G. Alexander

The Thetean: A Student Journal for Scholarly Historical Writing

Ordinarily. American historians divide the years from 1929 through 1945 into two periods. The time from 1929 to about 1939 they generally label· The Great Depression." In most cases, the chapter on the depression tells the story of American domestic affairs during the 1930s with a slight bow to the severity of worldwide economic conditions. In the next chapter, covering the years 1939 to 1945, historians discuss World War II; to do chis, however, they have to return to the 1920s to deal with the foreign affurs they neglected in the previous chapter. In discussing World War II, historians say …

Preface, Christopher Oscarson

The Thetean: A Student Journal for Scholarly Historical Writing

Every year, the reading staff of The Thetean has the formidable task of selecting just four or five interesting, well-written, insightful essays that appropriately illustrate the finest work done by history students at Brigham Young University. This year, perhaps because of the statewide Centennial statehood celebration, we received what seemed to be an unusually large number of papers dealing with Utah history in addition to the regularly large number of Mormon history papers. Our first impulse was to shy away from some of these essays simply co force diversity into the pages of The Thetean, but we ultimately felt char …

Front Matter

The Thetean: A Student Journal for Scholarly Historical Writing

No abstract provided.

Diagnosis And Treatment Of Helicobacter Pylori, Erin Raspet

Pacific Journal of Health

Helicobacter pylori is a widespread infectious disease most commonly associated with gastritis, peptic ulcer disease, and gastric cancer. The ability of this organism to influence immune function has been associated with a proinflammatory state that has been associated with several other conditions that can lead to significant mortality and morbidity. Treatment is possible with antibiotic regimens, however, increasing resistance requires treatment be informed by susceptibility information followed by a test of cure to ensure eradication of the infection. Given the global burden of this infection, it is important for providers to appropriately identify, diagnosis, and treat this condition to reduce …

The Play’S The Thing: A Response To Judge Benjamin Beaton, Aaron J. Walayat

Pepperdine Law Review

In a recent speech, later published as an essay, the Hon. Benjamin Beaton of the United States District Court for the Western District of Kentucky shared his critical suggestions against the use of the honorific “Your Honor,” preferring instead the more neutral title “judge.” Judge Beaton’s reason for this preference stems from a fear that the current practice of judicial titles emphasizes status over function, which may inflate the individual judge’s ego while miscommunicating to the public that judges make, rather than find, law. This position, however, is misguided. Judicial titles emphasize the authority of the law through the authority …

Continuing The Legacy: Navigating Grief And Loss While Pursuing A Degree, Sharon Lewis, Hope Charles, Nivischi Edwards

National Cross-Cultural Counseling & Education Conference for Research, Action & Change (2016-2024)

A 2013 study found 74.8% of Black girls graduated high school, while only 37.6% of the Black females in early adulthood were enrolled in college (Kalu, 2022). The added pressure of navigating grief while also endeavoring higher education only exacerbates that statistic. Learning to process grief healthfully is a useful lesson to ensure one’s ability to thrive during their grief.

U.S. Military Veteran Identity And Civilian Adjustment, Darren A. Sosa

Pacific Journal of Health

U.S. military veterans transitioning back into the civilian sector often experience a variety of challenges and need to readjust into non-military environments. In order to examine the psychological challenges involved in the transition and readjustment processes among U. S. active military veterans, a qualitative study was conducted. For 6 months, data was collected from veterans in California, Nevada, Texas, Florida, and New York. Following an IRB approval, semi-structured open-ended self-developed interviews were developed and conducted with sixteen military veterans who have served in 4 branches of the U.S. Armed Forces: Army, Navy, Air Force, and Marine Corps. Data and information …