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Modeling Sex-Specific Changes In Myocardial Fibrosis, Grace Martin

Chemical Engineering Undergraduate Honors Theses

Heart disease the leading cause of death for both men and women in the United States. Cardiac fibrosis, or accumulation of extracellular matrix proteins in the heart, can occur after a heart attack and increase the risk for further complications. Current treatments for heart disease do not include extracellular matrix regulators, partly due to the complicated signaling network responsible for the production of these proteins. By using a computational model of the signaling network in cardia fibroblasts, the relationship between particular molecules and downstream extracellular matrix production can be examined.

Biological sex is an important factor for cardiac health and …

An Examination Of Products That University Of Mississippi Students Consume For Managing Their Stress, Kiersten Rickard

Honors Theses

Students are notoriously one of the most stressed groups in our society. Stress is a complex topic; causes, mitigation methods, and manifestations of stress all vary in an individual. Being that stress is an universal experience, this research capitalizes on the importance of stress and the methods used to mitigate stress. This study looks at, among other ideas, stress on the University of Mississippi campus in regards to demographics and the products (caffeine, sleep aids, over the counter medicines, stress supplements, and CBD) that students use. Results demonstrate that, overall, higher stress levels correlate to higher product usage rates. The …

The Impact Of The 2002 Economic Crisis On Remittances & Emigration In Uruguay, Abigail Robeson

Honors Theses

Throughout 2002, the Uruguayan peso depreciated by 85 percent, causing an economic crisis and a rise in people searching outward for employment. This increased both the number of remittances received and emigration in an unprecedented way within Uruguay. Reports of remittances, and migration patterns of Uruguayans before 2002 are vastly different from those of the years following. Using quantitative analysis and a variety of data sources, this paper finds that the Uruguayan economic crisis undoubtedly spurred both remittance relevance and emigration in Uruguay. Emigration and remittances concerning Uruguay are seen to be permanently impacted by the crisis – though to …

Examining The Shared Decision-Making Preferences Of Adult Black Men With Hypertension In The U.S. Mid-South Region: A Mixed Methods Approach, Samantha Faith Calhoun

Theses and Dissertations (ETD)

Purpose. This study aimed to explore what factors are related to Black men’s shared decision-making (SDM) preferences for selecting hypertension (HTN) treatment and management options with a healthcare clinician. Methods. Researchers employed an exploratory sequential mixed methods design to explore factors influencing Black adult men's preferences for involvement in SDM regarding HTN treatment. Qualitative interviews with N=16 Black men identified factors related to SDM involvement, while a quantitative phase with N=105 Black men examined factors that could predict the level of involvement in SDM for HTN treatment. Results. Trust and having a female clinician were a significant independent predictor of …

Identifying Contributors To Acute Stroke Transfer Delays From Lower To Higher Level Stroke Centers, Jennifer Patterson

Theses and Dissertations (ETD)

The intricate process of efficiently transferring patients within the healthcare setting has proven to be complex however, it is a critical component to ensure timely access to essential medical interventions. Navigating these complexities presents a multifaceted challenge that is not fully understood. For patients suffering a stroke, these transfer delays may render them ineligible for treatment and left with disabling disability. This collective work aims to identify contributors to delays in transfer from lower to higher levels of care in the acute stroke populations.

Three papers emerged from this thesis. First, a narrative review of the literature published between January …

Barriers To Mental Health Treatment Among Medical Students: Preclinical Vs. Clinical Years, Urvashi Singh, Agnes Wrobel

Posters

Our study aims to:

• Investigate medical students’ attitudes towards seeking assistance from mental health professionals.
• Compare the importance of various barriers that deter help-seeking in preclinical vs. clinical years of medical education.

Clinical Differences In Isolated Post-Capillary Pulmonary Hypertension And Combined Pre- And Postcapillary Pulmonary Hypertension, Emily Schneider, Bhavinkumar D. Dalal

Posters

PULMONARY HYPERTENSION (PH) = RESTING MEAN PULMONARY ARTERY PRESSURE (MPAP) > 20 MMHG.

The World Health Organization recognizes five groups of pulmonary hypertensions:

• • Estimated that > 50% of patients with left heart disease are also affected by pulmonary hypertension.1
• 1 in 4 Americans will develop heart failure in their lifetime.
• Gold standard for diagnosis of PH is a right heart catheterization (RHC).3
• Global burden of PH remains unknown as this illness is poorly surveilled and cases remain underestimated.4,5

Assessing Barriers To Upward Mobility In The Cape Fear Region, Sabrina T. Cherry, Christopher R. Prentice

Journal of Sustainable Social Impact

Researchers explore upward mobility to better understand how economic and employment factors drive or undermine social justice and equity in the United States. This scholarship can inform activists and researchers seeking to design solutions that help overcome systemic challenges to upward mobility. Therefore, as an interdisciplinary team of scholars in a public university, we collaborated with community partners to conduct a case study in which we assessed the barriers to—and the drivers of—upward mobility in a medium-sized city in Southeastern North Carolina. We conducted key informant interviews and focus groups with a cross-section of local residents to learn about their …

Hay: A Hedonic Study, Chester R. Broadbent

All Graduate Reports and Creative Projects, Fall 2023 to Present

Hedonic price theory posits that the price of a product is influenced by the values consumers assign to its individual attributes. Hay is a versatile commodity with variation across several attributes helping to cater to diverse needs of consumers. A detailed analysis using hedonic regression techniques within hay pricing can help producers, stakeholders, and educators more fully understand the marginal values consumers place on diverse hay attributes. Previous studies focused on limited scopes within the hay industry or other sectors, allowing room for broader investigation. This study examines qualitative attributes impacting hay pricing, revealing significant influences from factors like location, …

Incidence Of Physical Activity And Academic Achievement In Virtual Learning Students, Jenna Arkelian-Brown

Doctorate in Kinesiology

The research assessed whether the incidence of physical activity was correlated with academic achievement. The population of participants included 43 students enrolled in virtual schooling. Academic achievement data was collected from participants’ virtual science/biology class, including their final semester 1 grade. Incidence of physical activity was assessed using the Physical Activity Questionnaire for Adolescents (PAQ-A) created by Kowalski et al. (2004). The PAQ-A was adapted to a Google Form, and physical activity summary scores were extracted and organized on Google Sheets for data analysis. Physical activity summary scores and student achievement data were inserted into a Pearson Correlation Coefficient Calculator. …

You’Re Testing My Patients: Clinicians’ Preferences For Structured Reporting And Measurement Data, Davit Melik, Adela Pouzar, Allan Brazier, Sayf Al-Katib

Posters

Radiological reports are a crucial part of patient care and management. Radiologists play a major role in patient care by interpreting imaging studies and making recommendations to referring physicians. 1,2,3 Although some physicians may prefer to initially interpret the imaging studies by themselves, radiologists’ reports have been shown to be significantly more accurate and detailed, which ultimately results in better patient care. 1,4,5,3 Thus it is important for radiology reports to be timely and as accurate as possible to improve overall patient care. The clarity of communication between radiologists and referring physicians in these reports remains an important factor in …

Study Of Morphology, Structure, And Magnetic Properties Of High Entropy Alloy Systems, Matthew G. Guerrero

Open Access Theses & Dissertations

Abstract:This thesis presents an investigation into the magnetic properties of high entropy alloy (HEA) samples, focusing primarily on compositions within the FeNiCoMn system and their gallium/chemically doped derivatives. High entropy alloys represent a promising class of materials with unique properties resulting from their complex composition and structural arrangements. The behavior of these alloys, particularly in their magnetic properties, remains an area of significant interest due to their potential applications in magnetic storage, sensing, and other technological domains. The study encompasses an examination of seven distinct HEA samples: FeNiCo, FeNiCoMn0.2, FeNiCoMn0.4, FeNiCoMn0.6, FeNiCoMn0.2Ga0.1, FeNiCoGa0.2, FeNiCoMn0.2Ga0.3. Furthermore, three samples of FeNiCoMn0.2 and …

Mechanical Stability Of Body-Centered Cubic Iron In Born-Von Kármán Parameter Space Using Evolutionary Algorithms, Amir Husen

Open Access Theses & Dissertations

This study aims to assess the mechanical stability of body-centered cubic (BCC) structure, focusing on pure iron as a representative case. The primary approach involves utilizing phonon dispersion curves analysis to gain insights into the vibrational properties and overall stability of the crystal lattice through a multi-faceted computational approach. The goal of the study is to find the regions (pockets) in Born-von Kármán (BvK) parameter space where the crystal is stable for certain temperature and pressure.

This involves setting up the crystal parameters, creating a body-centered cubic (BCC) crystal with specific lattice parameters (2.86 for iron) establishing force constants, and …

Biofabrication Of Human Tissue-On-A-Chip Models Using Engineered Biocompatible Electrospun Scaffolds, Zayra Naomi Dorado

Open Access Theses & Dissertations

This study explored the adoption of furfuryl gelatin (F-gelatin) based electrospun scaffolds compared with poly-caprolactone (PCL) as promising biomaterials for tissue engineering applications. Tissue-on-a-chip models, incorporating F-gelatin and PCL electrospun scaffolds, offer promising avenues for healthy and disease-in-vitro tissue models that can be explored to investigate underlying physiological mechanisms involved in disease development. Previous research has demonstrated the cytocompatibility of F-gelatin when used for modifying implant surfaces and tissue repair applications [1]. Our earlier published works have also successfully utilized F-gelatin for in-vitro cardiac tissue engineering [2][3]. We designed F-gelatin and PCL electrospun scaffolds to replicate the native tissue extracellular …

Navigating Improvement For A Master Of Occupational Therapy Program: Enhancing Content For A Mental Health Course, Emily Markovicz

Capstone Projects

Education is the forefront to the field of occupational therapy. As occupational therapists advocate for the significance of their profession, it is expected to grow further. In recent decades, the research of many health professions have increasingly explored the impact of trauma. As occupational therapy evolves to address this public health concern, more research, increased integration into occupational therapy curriculum, and clear practical guidelines are necessary. Considering the mental health risks stemming from adverse life events, the complexities of mental health conditions should remain a crucial part of occupational therapy education, ensuring that students are well-prepared to deliver optimal care …

Vesicant Infusates Are Not Associated With Ultrasound-Guided Peripheral Intravenous Catheter Failure: A Secondary Analysis Of Existing Data, Mahmoud Hijazi, Amit Bahl, Nai-Wei Chen

Posters

With over 300 million used annually in the United States, peripheral intravenous catheters (PIVC) are the most commonly used invasive device in the acute care setting1,2. Unfortunately, PIVCs have high failure rates with up to 63% failing prematurely3,4.

Certain intravenous medications categorized as vesicants and irritants are known to cause vein and local tissue injury. The Infusion Nursing Society (INS) created this list based on infusate osmolarity thresholds that increase the likelihood of these complications5.

It is perceived the impact of these medications on larger proximal veins with higher flow rates and improved hemodilution diminishes the likelihood of these complications. …

Mda At Your Service: How Can I Choose The Right Associate Position?, Kristin Johnson Dds

The Journal of the Michigan Dental Association

MDA Staff, with input from Membership Chair Kristin Johnson, DDS, advise dentists on various concerns: reviewing employment contracts with legal counsel, updating personal/practice info, obtaining MDA logo for websites, and enhancing visibility on Find a Dentist platforms. Legal and ethical considerations are highlighted when terminating difficult patient relationships. Membership benefits include contract reviews and promotional resources.

The New Professional: Navigating The Journey: Finding Your Practice Philosophy As A New Dentist, Amrita Patel Dds

The Journal of the Michigan Dental Association

Dr. Amrita Patel highlights the importance of defining a practice philosophy as a new dentist. Self-reflection, mentorship, patient-centered care, continuous learning, and adaptability are crucial elements in this journey. Embracing personal values and ethics ensures authenticity and guides decision-making. The evolving nature of this philosophy underscores the need for flexibility and openness to change. Dentists can shape their professional identity and approach to patient care through introspection and experiential learning.

J Mich Dent Assoc May 2024

The Journal of the Michigan Dental Association

Every month, The Journal of the Michigan Dental Association provides news, information, and features about Michigan dentistry to our state's oral health community and the MDA's 6,200+ members. It stands as the primary publication reaching Michigan dentists.

In the May 2024 issue, the Journal focuses on the landscape of practicing in rural settings. Original content includes:

• A cover story interview introducing MDA President Todd Christy

• A feature clinical case report on Proliferative Verrucous Leukoplakia Progressing to Squamous Cell Carcinoma

• Profiles of the 2024 MDA Awards Recipients

• A New Professional Column: “Navigating the Journey: Finding Your Practice Philosophy as a New …

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Mda Foundation: Mda Foundation Grant Helps Huda Clinic Celebrate 20 Years Of Service, Anne Berquist

The Journal of the Michigan Dental Association

MDA Foundation Director discusses the 20th anniversary of HUDA Clinic, Detroit's largest free clinic, providing crucial medical, dental, and mental health services to the uninsured. Supported by a $10,000 grant from the MDA Foundation, HUDA plans to expand dental services due to overwhelming demand, aiming to provide daily care. They seek volunteers and donations to meet the significant need, especially for dentures. Expansion plans include collaboration with local dental schools and community colleges.

Our Author Is Crazy, Zani A. Meaders

Open Access Theses & Dissertations

This thesis delves into the realm of young adult (YA) fantasy literature, exploring how its meta-narrative elements, fast-paced story beats, and relatable characters can facilitate the acquisition of healthy coping mechanisms among its readers. In the preface, I discuss the importance of providing YA audiences with narratives that not only entertain but also serve as tools for navigating the complexities of adolescence. Drawing upon psychological theories and literary analysis, I argue that meta-awareness in YA fantasy can offer readers a unique perspective on their own struggles and encourage them to develop resilience and coping skills.

The accompanying YA Fantasy story …

Becoming A Bilingual Teacher On The Border: Developing Ideological Clarity At A Hispanic-Serving Institution, Laura J. Salazar

Open Access Theses & Dissertations

As teacher education programs encourage more candidates to pursue bilingual certification, a need exists to improve the ways that preservice teachers (PSTs) are prepared to teach in bilingual classrooms. Research suggests the importance of preparing PSTs in the area of linguistic ideological clarity. Scholars define ideological clarity as an ongoing process through which individuals can critically consider their ideological orientations as well as dominant ideologies that favor those in power, with an aim of becoming agents of change through this process (Alfaro & Bartolomé, 2017). This case study sought to understand the opportunities that bilingual PSTs have to develop ideological …

Bcl2 Mediated Targeted Drug Delivery For The Treatment Of Kidney Fibrosis And Stomach Cancer, Humayra Afrin

Open Access Theses & Dissertations

Apoptosis, the programmed death of cells, is primarily regulated by a delicate balance between pro-apoptotic and anti-apoptotic signals. The Bcl-2 (B-cell lymphoma 2) family of proteins acts as anti-apoptotic agents, promoting cell survival. Dysregulation of these proteins is a common occurrence in conditions such as cancer and fibrosis, where overexpression of anti-apoptotic members can foster tumor cell survival and fibroblast activation. In this study, our aim was to explore the therapeutic potential of Bcl-2 inhibitors, both as a small molecule (specifically Navitoclax (Navi)), inhibitor and as Bcl-2 siRNA, for targeted treatment. Intravenous administration of Navi often leads to thrombocytopenia, necessitating …

Dentistry And The Law: Taking Records When Leaving A Practice, Dan Schulte Jd

The Journal of the Michigan Dental Association

MDA Legal Counsel Dan Schulte advises on departing partner issues: without contracts, disputes arise regarding records, patient ownership, and practice buyout. Employment and shareholder agreements ensure orderly transitions and protect practice interests. Patient records legally belong to the practice, and transferring them without consent violates laws. Patients can request records, but fees apply. Schulte stresses the importance of agreements to avoid costly disputes and ensure continuity of care.

Targeted-Sequencing Evaluation For Fzd4 Variants In Familial Exudative Vitreo-Retinopathy, Mary Drekh, Wendy Dailey, Vincent Le, Savyo Krikor, Kimberly A. Drenser, Kenneth P. Mitton

Posters

• The Familial hereditary vision loss disease may present with symptoms including retinal detachment, folding, neovascularization, or vitreous hemorrhage due to peripheral retina avascularity.
• The manifestation of FEVR genetically has been associated with a loss of function mutation of the Wnt/bcantenin-signaling pathway involving 7 genes (FZD4, NDP, CTNNB1, KIF11, LRP5, TSPAN12, and ZNF408). In our patient population of 72 individuals the distribution of FZD4 gene variants leading to FEVR has been recorded.
• The Frizzled4 gene (FZD4) codes for the G-coupled protein receptor and effects Wnt/b-cantenin-signaling pathway In endothelial cells.
• What frequency of FEVR from our patient pool will have FZD4 variants …

Supply Chain Management Internship – J.B. Hunt Transport Services, Inc., Garrett Locknar

Supply Chain Management Undergraduate Honors Theses

The transportation industry touches every facet of business: research and development, final mile services, raw material procurement, even technology innovation and application design. Without transportation of goods, people, and services, each business as we know would fall apart. The greater supply chain itself relies heavily on the presence and precision of transportation to create value for each specific company’s operations. Beginning in the summer of 2022, I have had the privilege of interning at J.B. Hunt Transport, Inc., one of the world’s largest logistics and transportation companies, which has opened my eyes to the sheer impact of transportation on each …

Primary Care Employees' Knowledge And Self Efficacy About Human Trafficking, Mollie Zehmer

Graduate Theses and Dissertations

Human trafficking is a worldwide issue that is detrimental to individuals, families, and communities. However, it is a hidden issue, and without proper training, it goes unnoticed. Many primary care employees do not know much about trafficking or how to identify trafficked persons, but with proper training they could potentially help clients that are trafficked persons. The purpose of this quasi-experimental study was to determine if human trafficking training would increase primary care employees’ knowledge and self-efficacy about human trafficking. The training included topics such as general knowledge, risk factors, identifiers, and the role of healthcare employees. Participants in the …

Exploring Peer Perspectives On Autistic Students: A Vignette Study, Justin Linville

Electronic Theses and Dissertations

A 2x2 design was undertaken to determine the effects of vignette character gender and autism disclosure status on social distance scores, reading comprehension performance, and false memory induction. The introduction focuses on the theoretical threads taken from the autism, false memory, and gender literatures and how they combine to create the underpinning of the current design. A second more controlled study was compelled by initial false impressions of the deleterious effects of fast completion times. This second study resulted in lengthened completion times and improved vignette comprehension. Two-way MANOVAs with gender and autism disclosure serving as independent variables on the …

“‘With God For Us, We Must Be Successful’: Nationalism, Slavery, And Death In The Civil War Letters Of Robert Franklin Bunting”, Stuart James Priest

Electronic Theses and Dissertations

Robert Franklin Bunting (b. 1828, d. 1891) was a preeminent Presbyterian minister, church planter, and Confederate chaplain. Before serving as a chaplain, he planted multiple churches in Central Texas. As a chaplain, he wrote numerous letters to various Texas newspapers. This thesis utilizes Bunting’s letters to understand how white southerners understood and interacted with the primary social issues in the Civil War. Specifically, it examines how Bunting understood nationalism, slavery, and death. His perception of these issues flowed from his religious worldview. As such, it highlights his religious interplay with these issues and contributes to furthering our understanding of religion's …

Engaging Students In Learning Music Theory Fundamentals And Preparing For College Level Music Theory, Marissa Aronson

Electronic Theses and Dissertations

The goal of this thesis is to provide teachers resources to prepare students for college-level music theory by using the keyboard. By providing visualization of patterns, the keyboard provides a superior tool to create a smooth transition between pre-college and college-level music theory instruction. In search of easing the passage between these levels, I interviewed numerous piano teachers who provided suggestions on how they include the keyboard to teach theory. After the interviews, I compared piano lesson theory books and college theory textbooks to compare their approaches. To assist with any gaps found in the theory books, I provide some …