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Advances In Research On Hydrogenation Saturation Of Polycyclic Aromatic Hydrocarbons In Coal Tar, He Xinfu, Gao Fan, Wu Hongju, Zhang Xiaoqin, Ma Tao, Shi Zhiwei, Zhou Anning, Zhang Yating

Coal Geology & Exploration

Significance Polycyclic aromatic hydrocarbons (PAHs), a predominant component in coal tar, can be used to produce jet fuels with high energy density and thermal stability through hydrogenation saturation. Based on the characteristics of the PAH hydrogenation process, this study proposed that primary challenges in PAH hydrogenation saturation include the resonance energy of PAHs themselves, the spatial site resistance of hydrogenation intermediates, and the competitive adsorption of feedstocks and intermediates on active sites in the catalysts. Progress Based on the review of research progress in catalysts for PAH hydrogenation saturation in recent years, this study analyzed the substantial factor influencing the …

Workplace Diversity, Equity, And Inclusion In The Retention Of Faculty Women Of Color In Science, Technology, Engineering, And Mathematics, Sherri Reese

Walden Dissertations and Doctoral Studies

Gender discrimination and the underrepresentation of women of color in faculty positions in higher education institutions, especially in the science, technology, engineering, and mathematics (STEM) departments, is a research and policy problem. Despite efforts to improve diversity and inclusion in higher education workplaces, women of color remain largely underrepresented among STEM faculty. Informed by Adams’s equity theory, Tajfel’s social identity theory of organizational commitment, and Bell’s critical race theory, the purpose of this quantitative cross-sectional study was to examine the relationship between diversity and organizational commitment and inclusion and organizational commitment among faculty women of color. Survey data were collected …

Decoding Anotylus (Thomson 1859) Beetle Diversity: Dna And External Morphology Match In Área De Conservacion Guanacaste, Costa Rica, K. Dante Underwood, Robert Puschendorf, David T. Bilton, Daniel H. Janzen, Winnie Hallwachs, M. Alex Smith

School of Biological and Marine Sciences

Taxonomy underpins biological research because names are needed for comparative analysis, conservation status, and public communication. Despite this, many species remain undescribed and are therefore vulnerable and unprotected, particularly in the tropics. Neotropical Staphylinidae beetles (Coleoptera) are among the insect groups most likely to contain significant unknown and/or cryptic diversity. Here we used an integrative taxonomic framework to conduct a preliminary review of one particularly diverse genus of Staphylinidae (Anotylus) in Área de Conservaciόn Guanacaste, northwestern Costa Rica. We began by DNA barcoding novel collections and using Barcode Index Numbers (BINs) as an estimate of taxonomic diversity; we found 18 …

Randomized, Double-Blind, Placebo-Controlled Study Of Anti-Mycobacterial Therapy (Rhb-104) In Active Crohn's Disease, David Y Graham, Saleh A Naser, Thomas Borody, Zbigniew Hebzda, Harry Sarles, Scott Levenson, Robert Hardi, Tomasz Arłukowicz, Petar Svorcan, Reza Fathi, Aida Bibliowicz, Patricia Anderson, Patrick Mclean, Clara Fehrmann, M Scott Harris, Shuhong Zhao, Ira N Kalfus

Faculty, Staff and Students Publications

This study, conducted between 4 October 2013, and 30 November 2018, tested the hypothesis that triple antimicrobial therapy, targeting Mycobacterium avium subspecies paratuberculosis (MAP), long considered a putative cause, would favorably affect Crohn’s disease. A double-blind multicenter study of adults with active Crohn’s disease, (i.e., Crohn’s Disease Activity Index [CDAI] 220–450 plus C-reactive protein ≥ 1.0 mg/dL, fecal calprotectin (FCP) >162.9 µg/g stool, or recent endoscopic or radiographic confirmation of active disease) receiving concomitant standard-of-care Crohn’s disease treatment (Clinicaltrials.gov: NCT01951326) were stratified by anti-tumor necrosis factor use and randomized (1:1) to anti-MAP RHB-104 (clarithromycin 95 mg, rifabutin 45 mg, …

Vertiport Ventures: Assessing Operational Feasibility For Evtol Integration In São Paulo’S Helipad And Heliport Infrastructure, Peter E. O'Reilly, Ramy A. Rahimi, Jorge Luiz Rosa Marques, Marco Aurélio Feitosa De A. L. Babadopulos1

Publications

The objective of this study is to assess the operational viability of introducing Electric Vertical Take-Of and Landing (eVTOL) vehicles in São Paulo and its metropolitan area, utilizing existing helipads and helicopter infrastructure. eVTOL aircraft, capable of vertical take-of and landing like helicopters, difer from traditional helicopters in their propulsion systems, with eVTOLs typically featuring multiple smaller electric motor-driven propulsion units instead of internal combustion engines and mechanical transmissions (Schuchardt et al. 2023). The study specifcally targets eVTOLs with the capacity to transport a minimum of four passengers and one pilot for distances of at least 50 km. Appendix provides …

In Vivo Evaluation Of Fatty Acid Loaded Chitosan Membranes For Pain Relief And Biofilm Associated Infection Prevention, Yogita Manasa Dintakurthi

Electronic Theses and Dissertations Archive

Infections are the leading cause of burn related deaths worldwide. These infections not only complicate micro-environment of a burn wound, but further obscure the wound due to the formation of biofilms at the wound site. Local drug delivery (LDD) has been a highly researched solution due to its advantages in locally treating and preventing infection while avoiding systemic side effects. LDD systems also have advantages for complex wounds, like burns. Chitosan is a natural polymer that is often used in these systems due to its biodegradability, biocompatibility and versatility. Previous research has suggested that short chain unsaturated fatty acids, for …

10-H2da Coating On Polyvinyl Chloride Catheter Biomaterials For Prevention Of Candida-Associated Urinary Tract Infections, Jermiah Tate

Electronic Theses and Dissertations Archive

Urinary catheters made of polyvinyl chloride (PVC) are susceptible to microbial biofilm formation. 10-hydroxy-2-decenoic acid (10-H2DA) is a dispersal signaling molecule that inhibits biofilm and planktonic growth of microorganisms. This study hypothesized that coating PVC with 10-H2DA would inhibit planktonic and biofilm-associated Candida albicans. Interactions of the PVC and 10-H2DA molecules were analyzed using Video Contact Angle (VCA), Fourier Transform Infrared (FTIR), and High-Performance Liquid Chromatography (HPLC). Successful coating of PVC with 10-H2DA was demonstrated through a significantly lowered contact angle and FTIR peaks in regions indicative of the 10-H2DA on the surface of PVC. Elution data displays a burst …

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Tert Activation Targets Dna Methylation And Multiple Aging Hallmarks, Hong Seok Shim, Jonathan Iaconelli, Xiaoying Shang, Jiexi Li, Zheng D Lan, Shan Jiang, Kayla Nutsch, Brittney A Beyer, Luke L Lairson, Adam T Boutin, Michael J Bollong, Peter G Schultz, Ronald A Depinho

Faculty, Staff and Student Publications

Insufficient telomerase activity, stemming from low telomerase reverse transcriptase (TERT) gene transcription, contributes to telomere dysfunction and aging pathologies. Besides its traditional function in telomere synthesis, TERT acts as a transcriptional co-regulator of genes pivotal in aging and age-associated diseases. Here, we report the identification of a TERT activator compound (TAC) that upregulates TERT transcription via the MEK/ERK/AP-1 cascade. In primary human cells and naturally aged mice, TAC-induced elevation of TERT levels promotes telomere synthesis, blunts tissue aging hallmarks with reduced cellular senescence and inflammatory cytokines, and silences p16INK4a expression via upregulation of DNMT3B-mediated promoter hypermethylation. In the brain, …

A Correctable Immune Niche For Epithelial Stem Cell Reprogramming And Post-Viral Lung Diseases, Kangyun Wu, Yong Zhang, Huiqing Yin-Declue, Kelly Sun, Dailing Mao, Kuangying Yang, Stephen R. Austin, Erika C. Crouch, Steven L. Brody, Derek E. Byers, Christy M. Hoffmann, Michael E. Hughes, Michael J. Holtzman

2020-Current year OA Pubs

Epithelial barriers are programmed for defense and repair but are also the site of long-term structural remodeling and disease. In general, this paradigm features epithelial stem cells (ESCs) that are called on to regenerate damaged tissues but can also be reprogrammed for detrimental remodeling. Here we identified a Wfdc21-dependent monocyte-derived dendritic cell (moDC) population that functioned as an early sentinel niche for basal ESC reprogramming in mouse models of epithelial injury after respiratory viral infection. Niche function depended on moDC delivery of ligand GPNMB to the basal ESC receptor CD44 so that properly timed antibody blockade of ligand or receptor …

Vaccine Value Profile For Hookworm, Karl Philipp Puchner, Maria Elena Bottazzi, Victoria Periago, Martin Grobusch, Rick Maizels, James Mccarthy, Bruce Lee, Erika Gaspari, David Diemert, Peter Hotez

Faculty, Staff and Students Publications

Hookworm, a parasitic infection, retains a considerable burden of disease, affecting the most underprivileged segments of the general population in endemic countries and remains one of the leading causes of mild to severe anemia in Low and Middle Income Countries (LMICs), particularly in pregnancy and children under 5. Despite repeated large scale Preventive Chemotherapy (PC) interventions since more than 3 decades, there is broad consensus among scholars that elimination targets set in the newly launched NTD roadmap will require additional tools and interventions. Development of a vaccine could constitute a promising expansion of the existing arsenal against hookworm. Therefore, we …

The Interplay Between Gender And Duration Of Hospitalization Modulates Psychiatric Symptom Severity In Subjects With Long Covid-19, Alessio Simonetti, Antonio Restaino, Claudia Calderoni, Emanuela De Chiara, Antonio Maria D'Onofrio, Salvatore Lioniello, Giovanni Camardese, Delfina Janiri, Matteo Tosato, Francesco Landi, Gabriele Sani

Faculty, Staff and Students Publications

Long COVID-19 is characterized by ongoing symptoms or prolonged or long-term complications of SARS-CoV-2 contraction which persist beyond 4 weeks from the initial onset of symptoms. Gender and duration of hospitalization (DH) are key risk factors for developing long COVID-19 syndrome, but their impact and interplay need further study. This research involved 996 long COVID-19 patients, and we compared the levels of general psychopathology, depression, agitated depression, anxiety, and medication use between hospitalized and non-hospitalized males and females. In the hospitalized patients, multivariate regressions assessed the impact of gender, DH, and the interaction of these variables. The females had higher …

Latinos' Intimate Partner Violence, Abuse, And Interventions: Developing A Latcrit Analysis And Critique, Adrian Luis Manriquez, Eric S. Mankowski

Psychology Faculty Publications and Presentations

The paper utilizes LatCrit and critical psychology perspectives in order to review and critique the literature on Latinos' intimate partner violence and abuse and intervention programs. LatCrit theories are described and reviewed, and then applied to the literature on IPV predictors among Latinos. The review demonstrates that the research literature on the predictors, correlates, and antecedents of Latino males' IPV behaviors focuses largely on the individual level of analysis, and consequently suffers from three main limitations: use of deficit models in research; decontextualized assessment and evaluations of IPV; neglect of higher levels of analysis influencing IPV in Latinx communities. Implications …

A Place To Rest My Soul: How A Doctoral Student Of Color Group Utilized A Healing-Centered Space To Navigate Higher Education, Jessica I. Ramirez

School of Social Work Faculty Publications and Presentations

Students of Color have historically faced explicit and implicit forms of discrimination and oppression in educational settings. Unfortunately, not much has changed over the decades as Students of Color continue to experience white supremacy and other systems of oppression. As Students of Color enter graduate school, there are often fewer Students of Color, making these educational settings isolating and hostile. These experiences often encompass white supremacist policies, practices, and remarks that negatively impact Students of Color. With this in mind and as someone who identifies as a Chicana who was once in a doctoral program, I questioned how doctoral Students …

Evaluating The Antibacterial Efficacy Of A Silver Nanocomposite Surface Coating Against Nosocomial Pathogens As An Antibiofilm Strategy To Prevent Hospital Infections, James Butler, Sian Morgan, Lewis Jones, Mathew Upton, Alexandros Besinis

School of Engineering, Computing and Mathematics

Antimicrobial nanocoatings may be a means of preventing nosocomial infections, which account for significant morbidity and mortality. The role of hospital sink traps in these infections is also increasingly appreciated. We describe the preparation, material characterization and antibacterial activity of a pipe cement-based silver nanocoating applied to unplasticized polyvinyl chloride, a material widely used in wastewater plumbing. Three-dimensional surface topography imaging and scanning electron microscopy showed increased roughness in all surface finishes versus control, with grinding producing the roughest surfaces. Silver stability within nanocoatings was >99.89% in deionized water and bacteriological media seeded with bacteria. The nanocoating exhibited potent antibiofilm …

The Arbitrariness Of Symmetry In Mathematical Proofs, Melisa Vivanco

Philosophy Faculty Publications

Symmetry is not an inherent characteristic of mathematical proofs; instead, it is a property that arbitrarily manifests in different modes of presentation. This arbitrariness leads to the conclusion that symmetry cannot be part of the defining or essential properties that characterize proofs. Consequently, contrary to some authors’ claims, symmetry does not significantly contribute to the validity, accuracy, or soundness of mathematical proofs. What is more, it does not even play any critical role in heuristic aspects such as explanatory power. The examples developed in this paper constitute compelling evidence supporting these claims.

An Expert System On Flimsy Foundations: Teaching Expertise And The Early Career Framework, Jim Hordern, Katherine Evans, Pete Kelly, Nick Pratt

School of Law, Humanities and Social Sciences

The paper seeks to identify how teacher expertise is implicitly and explicitly conceptualised in current English education policy in respect of the professional development of teachers. We focus specifically on conceptualisations of expertise in the Early Career Framework (ECF), both in terms of the policy documentation produced by the Department for Education and in terms of a selection of publicly available materials produced by the lead providers of the ECF. We aim to locate these conceptualisations in terms of broader sociological and philosophical debates about the nature of expertise and its relationship to professional work, in addition to recent research …

Review Of The Impact And Burden Of Urinary Urgency On Adults With Overactive Bladder, Adrian Wagg, A Lenore Ackerman, H Henry Lai, Diane K. Newman

2020-Current year OA Pubs

No abstract provided.

Blinatumomab For Mrd-Negative Acute Lymphoblastic Leukemia In Adults, Mark R Litzow, Geoffrey L Uy, Et Al.

2020-Current year OA Pubs

BACKGROUND: Many older adults with B-cell precursor acute lymphoblastic leukemia (BCP-ALL) have a relapse despite having a measurable residual disease (MRD)-negative complete remission with combination chemotherapy. The addition of blinatumomab, a bispecific T-cell engager molecule that is approved for the treatment of relapsed, refractory, and MRD-positive BCP-ALL, may have efficacy in patients with MRD-negative remission.

METHODS: In a phase 3 trial, we randomly assigned patients 30 to 70 years of age with

RESULTS: The data and safety monitoring committee reviewed the results from the third efficacy interim analysis and recommended that they be reported. Complete remission with or without full …

Identifying Promotion Strategies For Warungboto Tourism Village, Amri Nur Yahya, Haris Aulia Rahman

Jurnal Sosial Humaniora Terapan

Yogyakarta has about 17 tourist villages, each with its own unique potential as a tourist attraction. One of them is Warungboto Tourism Village, a village in the city of Yogyakarta that is currently used as a tourist destination, featuring four primary concepts: learning, art, culture, and history. However, as the village is relatively unknown due to a lack of promotion by its management. The local government and related tourism agencies should assist in promoting Warungboto Tourism Village as a tourist attraction. This promotion could help diversify tourist experiences and combat tourist fatigue, enhancing the appeal alongside other tourism sites. Additionally, …

Strategic Directions For Developing Smart Tourism: A Policy Framework By The Ministry Of Tourism And Creative Economy, Cintaku Hening Telaga Wibowo, Nusaiba Adzilla

Jurnal Sosial Humaniora Terapan

As the epicenter of Indonesia's government and economy, Jakarta is expected to spearhead the growth of the tourism industry. To meet this expectation in the context of the fourth industrial revolution and the era of digitalization, Jakarta’s tourism sector must be bolstered by various ICT applications. These applications are crucial for enhancing both the city's tourism competitiveness and the visitor experience. The concept of a "Smart Tourism City" has gained traction as a means to achieve these objectives. This concept focuses on smart tourist governance in terms of attractiveness, accessibility, readiness for digitalization, sustainability, and fostering partnerships. This study aims …

The Potential Influence Of Immune Modulatory Molecules (Tgf-Βiii And Ctla-4) In Pathogenicity Of Pcos, Mustafa Riyadh Abdullah, Hazima Mossa Alabassi

Karbala International Journal of Modern Science

Polycystic ovary syndrome (PCOS) is characterised by chronic anovulation, hyperandrogenism, polycystic ovaries, and immunological dysregulation. Immune homeostasis and inflammation management require immune functions. T-regulatory cells (Tregs) regulate PCOS's immune system, inflammation, insulin resistance, ovarian function, and homeostasis. Transforming growth factor βIII (TGF-βIII) and Cytotoxic-T-lymphocyte-associated-protein-4 (CTLA-4) receptors on the surfaces of Treg cells are important for controlling the immune system. The study included 68 PCOS patients and 22 non-PCOS women controls aged 20–45. The waist-hip ratio (WHR) determines obesity. We evaluated serum levels and gene expression of TGF-βIII and CTLA-4 via ELISA and real-time PCR. Women with PCOS had significantly higher …

Enhanced Optoelectronics Performance Of Hybrid Self Power Photodetectors Go: Tio2- Ad / N-Si Heterojunctions, Mohammed J. Alsultani, Maysoon F. Alias

Karbala International Journal of Modern Science

A GO:TiO₂/n-Si heterostructure has been submerged in an anthocyanin dye solution that extracted from the red cabbage plant creates a high responsivity, self-powered UV, and visible photodetectors fabricated by the spray pyrolysis technique. The GO concentrations are varied, whereas TiO₂ is fixed. Thin films' structure, shape, and optical characteristics were examined using X-ray diffraction, field emission scanning electron microscopy, and UV-Vis spectrophotometers respectively. Island-like polycrystalline film powders with grain boundaries and granular shapes are created. Two direct energy gaps between 3.33-3.02 and 2.39-2.04 eV exist in all films. J-V characteristics were examined. The saturation current density (J …

Study Impact Smoking On Sperm Morphology And Dna Fragmentation In Iraqi Male Fertility, Talal Z. Al-Darawsha, Mohammed H. Shaban, Ali H. Jawad

Al-Ameed Journal for Medical Research and Health Sciences

Background: Male infertility is issue a prevalent, involves various factors. Sperm quality, particularly influenced by smoking, is crucial for fertility. DNA fragmentation, indicating damage to DNA strands in sperm cells, is gaining importance in male infertility research, especially concerning abnormal sperm morphology.

Aim: To investigate the potential influence of smoking on both sperm morphology and DNA fragmentation in male fertility.

Materials and Methods: In this cross-sectional observational study, 83 participants (38 nonsmokers and 45 smokers) with Normozoospermia provided informed consent. Semen samples were collected following at WHO 2021 guidelines. Sperm morphology was evaluated using Kruger Strict Criteria with Hematoxylin stain, …

Interpretation Of Beauty Privilege In Film (Case Study Of Reception Analysis Of The “Backstage” Film), Jocelyn Jocelyn, Stefanus Andriano, Hardika Widi Satria Hardika Widi Satria

Jurnal Vokasi Indonesia

The "Backstage" film is an Indonesian film that addresses the issue of beauty privilege wrapped in a drama genre. Beauty privilege often occurs in Indonesia, creating injustices in society. This film tells the story of two siblings pursuing their careers, but injustice occurs in terms of popularity due to the differences in appearance between Sandra and Elsa. The problem lies in the difference in treatment they receive based on their conformity to beauty standards. This study aims is to understand and analyze the meaning of beauty privilege as perceived by the audience after watching the film "Backstage". The theories used …

Graduate Healthcare Students' Mental Health: A Pilot Study, Soriya S. Ung-Koy, Lindsay Gietzen

Pacific Journal of Health

This pilot study investigates the mental health of healthcare professional doctoral students, focusing on stress, anxiety, and depression, which can lead to burnout. These students are responsible for intense academic demands, personal lives, and professional careers.

This study explored student mental health in the Doctor of Medical Science (DMSc)/ Doctor of Health Science (DHSc) programs at the University of the Pacific's School of Health Sciences. The study contributes to existing literature, exploring how educational experiences impact healthcare students' mental health, behaviors, and symptoms.

The DASS-21 survey tool was utilized to assess anxiety, depression, and stress symptoms during their graduate studies. …

Uniformly Distributing Points On A Sphere, Flavio Arrigoni

Rose-Hulman Undergraduate Mathematics Journal

In this paper, we are going to present and discuss different procedures for distributing points on a sphere's surface. Furthermore, we will assess their quality with three different distribution tests. The MATHEMATICA package that we created for testing and plotting the points is publicly available.

Modeling Virus Diffusion On Social Media Networks With The Smirq Model, Justin Browning, Arnav Mazumder, Gowri Nanda

Rose-Hulman Undergraduate Mathematics Journal

As social networking services become more complex and widespread, users become increasingly susceptible to becoming infected with malware and risk their data being compromised. In the United States, it costs the government billions of dollars annually to handle malware attacks. Additionally, computer viruses can be spread through schools, businesses, and individuals’ personal devices and accounts. Malware affecting larger groups of people causes problems with privacy, personal files, and financial security. Thus, we developed the probabilistic SMIRQ (pSMIRQ) model that shows how a virus spreads through a generated network as a way to track and prevent future viruses. Our model is …

Approximating Equilibria In Restricted Games, Jack W. Doyle

Rose-Hulman Undergraduate Mathematics Journal

We consider optimal play in restricted games with linear constraints, and use ϵ-equilibria to find near-equilibrium states in these games. We present three mathematical optimization formulations -- a mixed-integer linear program (MILP), a quadratic program with linear constraints (QP), and a quadratically constrained program (QCP) -- to both approximate and identify these states. The MILP has a short runtime relative to the QP and QCP for large games (a factor 100 faster for |S|=9) and exhibits linear growth in run time, but provides only relatively weak upper bound. The QP and QCP provide a tight bound and the precise value …

Through Rotor Flow Architecture For Bearing Cooling

Defensive Publications Series

Two stage centrifugal compressors especially with a single sided wheel architecture face significant thrust loads. The proposed solution uses a relief hole in the impeller combined with a through hole in the shaft that allows gas flow from the first stage to flow through the rotor and cool the rear journal bearing. This flow architecture reduces the thrust loads significantly and improves efficiency by cooling the rotor along with bearings.