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Symptom Profiles In Head And Neck Cancer Patients Treated With Radiation Therapy: A Prospective Study, Parshawn Gerafian, Laia Humbert Vidan, Clifton Fuller Md, Phd, Amy Moreno Aug 2024

Symptom Profiles In Head And Neck Cancer Patients Treated With Radiation Therapy: A Prospective Study, Parshawn Gerafian, Laia Humbert Vidan, Clifton Fuller Md, Phd, Amy Moreno

CATALYST Summer Training Program 2024

No abstract provided.


Maximizing Legged Accelerations: A Matter Of Force, Time, And Gravity, Lance Brooks Aug 2024

Maximizing Legged Accelerations: A Matter Of Force, Time, And Gravity, Lance Brooks

Applied Physiology and Wellness Theses and Dissertations

Sprint running accelerations require runners to apply surface forces that: support body weight by pushing downward, accelerate the body horizontally by pushing backward, and align the direction of the push with the body’s mass center to maintain balance and posture, which imposes an upper limit on the average forward acceleration force equal to the average gravitational force (1.0 G) acting on the runner. This expectation arises from the mechanical constraints imposed by the need to generate sufficient vertical force to support body weight against gravity while simultaneously producing horizontal force to accelerate forward and aligning the push through the center …


The Efficacy Of Common Prosthetic Joint Infection Prevention Strategies: A Systematic Review, Cameron Jennings Aug 2024

The Efficacy Of Common Prosthetic Joint Infection Prevention Strategies: A Systematic Review, Cameron Jennings

Theses and Graduate Projects

Thousands of total hip and knee arthroplasty patients suffer from prosthetic joint infections every year, making them a leading cause of arthroplasty failure. As the number of these procedures continues to grow, so will the healthcare and socio-economic burden of prosthetic joint infections. A comprehensive search for up-to-date literature was completed via the PubMed database, identifying eighteen retrospective and prospective cohort studies that focused on the four prosthetic joint infection prevention methods of interest. Tobacco use cessation of all forms is an efficacious prosthetic joint infection prevention strategy. The common practices of withholding intra-articular injections prior to surgery, using prophylactic …


Decreasing Incivility And Bullying Through The Development Of A Healthy, Respectful Work Culture, Bridgette Wilson Aug 2024

Decreasing Incivility And Bullying Through The Development Of A Healthy, Respectful Work Culture, Bridgette Wilson

Master's Projects and Capstones

Abstract

Problem: Incidents of bullying and incivility, including verbal aggression and exclusionary practices within the Telemetry department.

Context: This quality improvement project addresses workplace incivility, bullying, and harassment. The project aims to develop and implement a Compact Agreement of Unit Norms to foster a healthier work environment.

Interventions: Interventions included leadership education on bullying and conflict resolution, team awareness was heightened through workshops defining bullying and incivility, and a collaborative Compact Agreement of Unit Norms was developed and implemented.

Measures: An analysis of reported incidents for the first quarter of 2024 through the Electronic Reposting System (ERRF) on the Telemetry …


Immunological Feedback Loops Generate Parasite Persistence Thresholds That Explain Variation In Infection Duration, Clayton E. Cressler, Daniel C.G. Metz, David A. Chang Van Oordt, Andrea L. Graham Aug 2024

Immunological Feedback Loops Generate Parasite Persistence Thresholds That Explain Variation In Infection Duration, Clayton E. Cressler, Daniel C.G. Metz, David A. Chang Van Oordt, Andrea L. Graham

School of Biological Sciences: Faculty Publications

Infection duration affects individual host fitness and between-host transmission. Whether an infection is cleared or becomes chronic depends on the complex interaction between host immune responses and parasite growth. Empirical and theoretical studies have suggested that there are critical thresholds of parasite dose that can determine clearance versus chronicity, driven by the ability of the parasite to manipulate host immunity. However, the mammalian immune response is characterized by strong positive and negative feedback loops that could generate duration thresholds even in the absence of direct immunomodulation. Here, we derive and analyse a simple model for the interaction between T-cell subpopulations …


Nfl Franchise Departures And Nearby Home Prices, Brad R. Humphreys, Geoffrey Propheter Aug 2024

Nfl Franchise Departures And Nearby Home Prices, Brad R. Humphreys, Geoffrey Propheter

Economics Faculty Working Papers Series

Research shows that US professional sports facilities positively impact nearby house prices. New facilities typically have existing teams, complicating a separate assessment of the impact of teams and facilities. Existing research analyzed departures of pro basketball teams, but arenas host many non-sporting events. These results may not generalize. We exploit the relocation of two professional football teams to investigate the impact of team departures on home sales. Difference-in-differences and repeat sales model results indicate proximity to one team represented an amenity while proximity to the other did not. Differences in urban form likely explains this heterogeneity.


Developing Alternative Grading Strategies, Brian M. Sackett Aug 2024

Developing Alternative Grading Strategies, Brian M. Sackett

Masters Projects

Traditional grading strategies may not accurately reflect student knowledge. Educators are beginning to develop more accurate and efficient methods for grading students. These alternative methods include; standards based grading, content based grading, portfolio assessment, narrative feedback, and minimum grading. These grading strategies focus more heavily on content mastery, rather than non-academic variables such as student behavior. This project will provide a thorough training session to teachers to give them the confidence to implement the new alternative grading strategies. The goal of this project is to have a lasting impact on students’ academic success as well as their motivation and engagement. …


Retrospective Dosimetric Comparison Of Radiation Therapy Treatment Using Hybrid-Vmat Technique For Esophageal Cancer, Colleen Cozzie Aug 2024

Retrospective Dosimetric Comparison Of Radiation Therapy Treatment Using Hybrid-Vmat Technique For Esophageal Cancer, Colleen Cozzie

Masters Projects

Abstract

Introduction

Esophageal cancer is the fifth most common gastrointestinal cancer in the United States. As oncology treatment includes radiation as a standard of care, it is vital to examine effective treatment delivery options. Understanding the dosimetric differences between VMAT and hybrid-VMAT can help providers choose the most appropriate care plan for patients undergoing esophageal irradiation. The purpose of this study was to evaluate if VMAT or hybrid-VMAT delivery would be the superior planning method for patients with planning target volumes greater than ten centimeters. Adequately covering the tumor volume while sparing dose to adjacent critical structures is the goal …


Projected Climate Change Impacts On The Number Of Dry And Very Heavy Precipitation Days By Century’S End: A Case Study Of Iran’S Metropolises, Rasoul Asfari, Mohammad Nazari-Sharabian, Ali Hosseini, Moses Karakouzian Aug 2024

Projected Climate Change Impacts On The Number Of Dry And Very Heavy Precipitation Days By Century’S End: A Case Study Of Iran’S Metropolises, Rasoul Asfari, Mohammad Nazari-Sharabian, Ali Hosseini, Moses Karakouzian

Civil and Environmental Engineering and Construction Faculty Research

This study explores the impacts of climate change on the number of dry days and very heavy precipitation days within Iran’s metropolises. Focusing on Tehran, Mashhad, Isfahan, Karaj, Shiraz, and Tabriz, the research utilizes the sixth phase of the Coupled Model Intercomparison Project (CMIP6) Global Circulation Models (GCMs) to predict future precipitation conditions under various Shared Socioeconomic Pathways (SSPs) from 2025 to 2100. The study aims to provide a comprehensive understanding of how climate change will affect precipitation patterns in these major cities. Findings indicate that the SSP126 scenario typically results in the highest number of dry days, suggesting that …


Effects Of E-Cigarettes On The Lung And Systemic Metabolome In People With Hiv, Aline Zaparte, Courtney J. Christopher, Connie Arnold, Lauren Richey, Adairre Castille, Kyle Mistretta, Christopher M. Taylor, Huiyi Lin, Steve Nelson, John P. Kirwan, John W. Apolzan, Shawn R. Campagna, David A. Welsh Aug 2024

Effects Of E-Cigarettes On The Lung And Systemic Metabolome In People With Hiv, Aline Zaparte, Courtney J. Christopher, Connie Arnold, Lauren Richey, Adairre Castille, Kyle Mistretta, Christopher M. Taylor, Huiyi Lin, Steve Nelson, John P. Kirwan, John W. Apolzan, Shawn R. Campagna, David A. Welsh

School of Medicine Faculty Publications

The popularity of e-cigarettes (vaping) has soared, creating a public health crisis among teens and young adults. Chronic vaping can induce gut inflammation and reduce intestinal barrier function through the production of the proinflammatory molecule hydrogen sulfide (H2S). This is particularly concerning for people with HIV (PWH) as they already face impaired immune function and are at a higher risk for metabolic dysregulation, diabetes, and chronic liver disease. Furthermore, PWH experience unhealthy behaviors, making it crucial to understand the systemic metabolic dysregulation and pathophysiological mechanisms associated with vaping in this population. Here, we employed liquid chromatography–mass spectrometry (LC-MS)-based metabolomics to …


Exploring The Feasibility Of Bidirectional Control Of Beta Oscillatory Power In Healthy Controls As A Potential Intervention For Parkinson’S Disease Movement Impairment, Krithika Anil, Giorgio Ganis, Jennifer Freeman, Jonathan Marsden, Stephen Hall Aug 2024

Exploring The Feasibility Of Bidirectional Control Of Beta Oscillatory Power In Healthy Controls As A Potential Intervention For Parkinson’S Disease Movement Impairment, Krithika Anil, Giorgio Ganis, Jennifer Freeman, Jonathan Marsden, Stephen Hall

School of Health Professions

Neurofeedback (NF) is a promising intervention for improvements in motor performance in Parkinson’s disease. This NF pilot study in healthy participants aimed to achieve the following: (1) determine participants’ ability to bi-directionally modulate sensorimotor beta power and (2) determine the effect of NF on movement performance. A real-time EEG-NF protocol was used to train participants to increase and decrease their individual motor cortex beta power amplitude, using a within-subject double-blind sham-controlled approach. Movement was assessed using a Go/No-go task. Participants completed the NASA Task Load Index and provided verbal feedback of the NF task difficulty. All 17 participants (median age …


Role Of Remediation In Cases Of Serious Misconduct Before Uk Healthcare Regulators: A Qualitative Study, Tristan Price, Marie Bryce, Tom Gale, Ellie Reynolds, Oliver Quick, Timothy O'Brien Aug 2024

Role Of Remediation In Cases Of Serious Misconduct Before Uk Healthcare Regulators: A Qualitative Study, Tristan Price, Marie Bryce, Tom Gale, Ellie Reynolds, Oliver Quick, Timothy O'Brien

Peninsula Medical School

Background: The raison d’etre of healthcare profession regulators across the globe is to protect patients and the public from the risk of harm. In cases of serious misconduct, remediation is deemed to be an important factor when considering the risk of harm from a practitioner under investigation. Yet, we know very little about how regulators account for remediation in their decision-making, and whether it is consistent with the aim of risk reduction. This paper explores the role of remediation in decision-making in cases of serious misconduct before UK healthcare regulators. Methods: We conducted interviews with 21 participants from across eight …


Cbt-I Training For The Mental Health Clinician To Deliver Evidence-Based Treatment To Address Impaired Sleep Quality In A Correctional Facility, Huong Madrigal Aug 2024

Cbt-I Training For The Mental Health Clinician To Deliver Evidence-Based Treatment To Address Impaired Sleep Quality In A Correctional Facility, Huong Madrigal

Doctor of Nursing Practice Scholarly Projects

Abstract

Description of the Problem: Insomnia significantly impacts mental and physical well-being, with long-term health effects and considerable healthcare costs. While pharmacological treatments offer temporary relief for some, they do not always provide lasting solutions.

Available Knowledge: A PRISMA-guided literature review found that training programs for cognitive-behavioral therapy for insomnia (CBT-I) are effective in increasing knowledge and confidence for addressing impaired sleep.

Aim and Objectives: This project aimed to enhance mental health clinicians' ability to assess and treat impaired sleep, focusing on implementing a tailored CBT-I educational initiative in a correctional facility.

Intervention: This project implemented evidence-based CBT-I …


Developing Conflict Resolution Skills In Residential Students At Higher Education Institutions, Lindsey A. Bos Aug 2024

Developing Conflict Resolution Skills In Residential Students At Higher Education Institutions, Lindsey A. Bos

Masters Projects

For many college students, living on campus is the first experience that students have living outside their familial home. Students may take this leap with people they have developed prior relationships with, or with people they have just met. Regardless, this collision of differing norms has the potential to lead to interpersonal conflict. To support residential students at higher education institutions, this project utilizes the theoretical lenses of Maslow’s (1943) hierarchy of needs, Sanford’s (1966) challenge and support theory, and Chickering’s (1969) seven vectors of development to create a workshop curriculum aimed at developing students’ conflict resolution skills. Highlighting the …


Fighting For The Right To Learn: Exploring The Impact Of Discipline Policies On Black Female Students, Amyre E. Smith Aug 2024

Fighting For The Right To Learn: Exploring The Impact Of Discipline Policies On Black Female Students, Amyre E. Smith

Masters Projects

This study investigates the systemic biases and stereotypes that disproportionately affect Black female students in K-12 educational settings. The research aims to analyze how implicit biases and societal norms contribute to the unfair policing and mistreatment of Black girls in schools. Utilizing a combination of literature review, case studies, and interviews, the study explores the intersectionality of race and gender and its impact on disciplinary actions. Findings reveal that Black girls are often disciplined for subjective offenses, such as defiance and disrespect, rooted in implicit biases held by school personnel. The study also evaluates the effectiveness of restorative practices and …


Ucf Pegasus Plan - 4th Grade - The Roaring 20s And How It Led To The Great Depression, Meagan Thibodeau, Brianna Hall, Gabrielle Hines Aug 2024

Ucf Pegasus Plan - 4th Grade - The Roaring 20s And How It Led To The Great Depression, Meagan Thibodeau, Brianna Hall, Gabrielle Hines

Pegasus Plans: Social Studies Unit Plans for Florida Teachers

During this unit, students will explore The Roaring 20s and The Great Depression. Students will also explore the culture, women's rights, transportation, and Florida tourism in the 1920s. They will learn about Florida's Land Boom and Bust, life during the Great Depression, and Franklin D. Roosevelt's New Deal.


Balancing Ecology And Practicality To Rank Waterbodies For Preventative Invasive Species Management, Caleb P. Roberts, William E. Grant, Matthew L. Horton, Lindsey A.P. Labrie, Miranda R. Peterson, Jane S. Rogosh, Hsiao-Hsuan Wang Aug 2024

Balancing Ecology And Practicality To Rank Waterbodies For Preventative Invasive Species Management, Caleb P. Roberts, William E. Grant, Matthew L. Horton, Lindsey A.P. Labrie, Miranda R. Peterson, Jane S. Rogosh, Hsiao-Hsuan Wang

Biological Sciences Faculty Publications and Presentations

  • ‘Early detection and rapid response’ (EDRR) is the most successful framework for preventative invasive species management, but prioritizing localized EDRR actions with limited resources is challenging. An approach that ranks individual locations, such as waterbodies, for EDRR by combining an invasive species' establishment risk with the practicality of managing it could help set reasonable priorities.
  • Here, we worked with regional practitioners in Arkansas, USA, and the broader Southeastern USA to co-produce a workflow for preventative aquatic invasive species management that (1) estimates establishment risk under current and future climates with a species distribution model, (2) scores waterbodies according to difficulty …


Electrochemical Cells For Harvesting And Storing Energy And Devices Including The Same, Arash Takshi, Belqasem Aljafari, Manoj Ram Aug 2024

Electrochemical Cells For Harvesting And Storing Energy And Devices Including The Same, Arash Takshi, Belqasem Aljafari, Manoj Ram

USF Patents

Electrochemical cells that include composite gel positioned between the first electrode and second electrode, where the composite gel comprises an electrolyte, a polyaryl amine, and an oxidant. The utilized composite gels are easy to produce at a low-cost, which makes them suitable in a number of different applications electrochromic devices, supercapacitors, solar cells, and hybrid photoactive supercapacitors.


Using Phylogenomics And Herbarium Specimens To Evaluate Relationships In The Plant Genus Aneilema, Family Commelinaceae., Allan Sampao Loinyio Aug 2024

Using Phylogenomics And Herbarium Specimens To Evaluate Relationships In The Plant Genus Aneilema, Family Commelinaceae., Allan Sampao Loinyio

Masters Theses

The genus Aneilema, with approximately 65 species in seven sections, is one of the largest genera in the Commelinaceae. It is mostly distributed across Australia, Madagascar, and Africa, but one species occurs in South America. Early molecular phylogenetic analyses based on a few chloroplast genes and a small number of species have supported the monophyly of the genus with the inclusion of Rhopalephora, which was nested within Aneilema. This study used the Angiosperms353 gene set to investigate the evolutionary and taxonomic relationships within the genus and its close relatives. Through molecular phylogenetic analyses of 35 Aneilema species …


The Effects Of Online Chemistry-Themed Design-Based Stem Education On Preservice Science Teachers’ Stem Awareness, Emine Sahin Topalcengiz, Burcin Acar-Sesen Aug 2024

The Effects Of Online Chemistry-Themed Design-Based Stem Education On Preservice Science Teachers’ Stem Awareness, Emine Sahin Topalcengiz, Burcin Acar-Sesen

Curriculum and Instruction Faculty Publications and Presentations

The study investigated the impact of Chemistry-Focused Online Science, Technology, Engineering, and Mathematics (STEM) teacher education on the awareness of STEM among preservice science teachers. A one-group pretest–posttest quasi-experimental weak design was used to determine changes in preservice teachers’ STEM awareness. During the study, a 14-week Chemistry-Focused Online STEM course was provided to preservice science teachers. As part of this course, the theoretical knowledge about STEM was explained to students, and afterward, they completed two modules. Furthermore, preservice teachers also developed their chemistry-themed STEM lesson plans at the beginning of the course, after explaining theoretical knowledge about STEM at the …


Knowledge Management Of Historical Data: Ontology Development For Chemical Reactions, Quynh D. Tran, Alexander Harding Bradley, Balashanmuga Priyan Rajamohan, Jonathan E. Gordon, Van D. Tran, Kiefer Lin, Erika I. Barcelos, Laura S. Bruckman, Roger H. French Aug 2024

Knowledge Management Of Historical Data: Ontology Development For Chemical Reactions, Quynh D. Tran, Alexander Harding Bradley, Balashanmuga Priyan Rajamohan, Jonathan E. Gordon, Van D. Tran, Kiefer Lin, Erika I. Barcelos, Laura S. Bruckman, Roger H. French

Researchers, Instructors, & Staff Scholarship

Knowledge management of the literature and historical data is critical to accelerated drug and materials discovery. Currently, literature knowledge is scattered in journal articles in various formats: diagrams, texts, plots, etc. Historical data from past experiments are saved in a number of local computers under confusing folder structures with ambiguous file names. To manage and organize historical data and knowledge, our group (SDLE) at CWRU follows FAIR (Findable, Accessible, Interoperable, Reusable) principles, which outline the best practices for data stewardship and data provenance, and ontology, a formal representation of terms and concepts and their relationships, as a tool to improve …


Tackling No-Shows In Fine Dining: Insights Into Cancellation Policies And Consumer Awareness Campaigns, Esther Kim, Jason Tang Aug 2024

Tackling No-Shows In Fine Dining: Insights Into Cancellation Policies And Consumer Awareness Campaigns, Esther Kim, Jason Tang

Department of Hospitality and Tourism Faculty Scholarship and Creative Works

This research aims to identify how fine dining restaurants can effectively implement reservation cancellation policies to address the issue of no-shows by applying equity theory, the dual entitlement principle, and social cognitive theory. Two experiments identified cancellation policy elements that influence restaurant evaluations and reservation behaviors. Findings revealed that cancellation policies negatively influence restaurant evaluations, and that policy strictness and awareness can attenuate this relationship via perceived fairness while enhancing the likelihood to book reservations and honor reservations. This research suggests that restaurants can benefit from implementing lenient cancellation policies and introducing awareness of the adverse impact of no-shows to …


Fragility Analysis And Systematic Review Of Patellar Resurfacing Versus Non-Patellar Resurfacing In Total Knee Arthroplasty, Teja Polisetty, Alexandra L. Hohmann, Eric Didomenico, Jess H. Lonner Aug 2024

Fragility Analysis And Systematic Review Of Patellar Resurfacing Versus Non-Patellar Resurfacing In Total Knee Arthroplasty, Teja Polisetty, Alexandra L. Hohmann, Eric Didomenico, Jess H. Lonner

Rothman Institute Papers

INTRODUCTION: Fragility analysis is a method of further characterising the robustness of statistical outcomes. This study evaluates the statistical fragility of randomised controlled trials (RCTs) comparing patellar resurfacing versus non-patellar surfacing in total knee arthroplasty (TKA).

METHODS: PubMed, MEDLINE and EMBASE were searched for RCTs comparing outcomes in TKA based on patellar resurfacing. Fragility index (FI) and reverse FI (collectively, "FI") were calculated for dichotomous outcomes as the number of outcome reversals needed to change statistical significance. Fragility quotient (FQ) was calculated by dividing the FI by the sample size for that outcome. Median FI and FQ were calculated for …


Assessment Approaches For Hemiplegic Shoulder Pain In People Living With Stroke–A Scoping Review, Praveen Kumar, Avgi Christodoulou, Michael Loizou Aug 2024

Assessment Approaches For Hemiplegic Shoulder Pain In People Living With Stroke–A Scoping Review, Praveen Kumar, Avgi Christodoulou, Michael Loizou

School of Nursing and Midwifery

Purpose: Hemiplegic shoulder pain (HSP) is reported in up to 40% of people with stroke. Causes of HSP are often multifactorial. To inform appropriate treatment, reliable/valid assessments are critical. The aim of this scoping review was to collate assessment approaches used in studies where the primary outcome was HSP, and to identify how frequently each assessment approach was used. Methods: A systematic search, including studies from 2000-2023 was conducted of the MEDLINE, EMBASE, CINAHL, AMED, Biomed Central, and Cochrane Library databases, with four key terms used: “assess”, “stroke”, “pain” and “shoulder”. All primary studies published in English language fulfilling the …


Navigating The Academic Labyrinth: Describing The Landscape Of Women Faculty In Hospitality Higher Education, Kelly A. Way, Clarissa Mason, Betsy Garrison Aug 2024

Navigating The Academic Labyrinth: Describing The Landscape Of Women Faculty In Hospitality Higher Education, Kelly A. Way, Clarissa Mason, Betsy Garrison

Human Development and Family Sciences Faculty Publications and Presentations

Purpose

The purpose of the study was to describe faculty women’s perspectives of the workplace environment in hospitality higher education. Design/methodology/approach

Female faculty members in hospitality (n = ∼50) completed an online survey about their beliefs about women’s experiences, advancement characteristics the glass ceiling and gender equity. Findings

Respondents concurred that being self-directed, assertive and a risk-taker were essential; leadership is the most important characteristic for advancement and the glass ceiling is prevalent and prominent. It may be assumed that the milieu of academia would be free or freer of the glass ceiling, but research, including this study, suggests otherwise. …


Empty State Electronics, Reza Farsad Asadi Aug 2024

Empty State Electronics, Reza Farsad Asadi

Electrical Engineering Theses and Dissertations

Field emitter arrays (FEAs) have the potential to operate at high frequencies and withstand harsh environments, such as radiation and high temperatures. However, they are sensitive to gaseous environments. This study examines the impact of different gas environments on silicon (Si) and gallium nitride (GaN) FEAs. To investigate the failure mechanisms, a vacuum system was designed and fabricated to monitor emission uniformity using a phosphor screen. Additionally, a vacuum system was created to introduce high-purity gases into the chamber while operating the devices. The results indicate that both types of FEAs are susceptible to oxidizing environments. Argon (Ar) did not …


Inclusive Excellence In Collections, Katy Kelly Aug 2024

Inclusive Excellence In Collections, Katy Kelly

University Libraries Blog Archive

Every student will use a book, scholarly journal, newspaper, streaming video or other information resource in their time at University of Dayton. As one of its core services, University Libraries select and purchase materials and make them available.


Stanniocalcin 2 Governs Cancer Cell Adaptation To Nutrient Insufficiency Through Alleviation Of Oxidative Stress, Shuo Qie, Haijuan Xiong, Yaqi Liu, Chenhui Yan, Yalei Wang, Lifeng Tian, Chenguang Wang, Nianli Sang Aug 2024

Stanniocalcin 2 Governs Cancer Cell Adaptation To Nutrient Insufficiency Through Alleviation Of Oxidative Stress, Shuo Qie, Haijuan Xiong, Yaqi Liu, Chenhui Yan, Yalei Wang, Lifeng Tian, Chenguang Wang, Nianli Sang

Department of Pharmacology, Physiology, and Cancer Biology Faculty Papers

Solid tumours often endure nutrient insufficiency during progression. How tumour cells adapt to temporal and spatial nutrient insufficiency remains unclear. We previously identified STC2 as one of the most upregulated genes in cells exposed to nutrient insufficiency by transcriptome screening, indicating the potential of STC2 in cellular adaptation to nutrient insufficiency. However, the molecular mechanisms underlying STC2 induction by nutrient insufficiency and subsequent adaptation remain elusive. Here, we report that STC2 protein is dramatically increased and secreted into the culture media by Gln-/Glc- deprivation. STC2 promoter contains cis-elements that are activated by ATF4 and p65/RelA, two transcription factors activated by …


Stories About The David Rowlands Family Of Ellensburg, Washington, Joy Main Smith Aug 2024

Stories About The David Rowlands Family Of Ellensburg, Washington, Joy Main Smith

Works by Local Authors

Including David's upbringing in Montgomeryshire Wales, his brother Robert's coming to America first, his siblings who stayed in the United Kingdom, and his 32 years with the Northern Pacific Railroad in Ellensburg.


Enhancing Fundraising Strategies In Higher Education Through Machine Learning, Laith Alatwah Aug 2024

Enhancing Fundraising Strategies In Higher Education Through Machine Learning, Laith Alatwah

Electrical Engineering Theses

This thesis presents a comprehensive application of machine learning techniques, namely Fine Gaussian SVM and RUS Boosted Trees, to enhance fundraising strategies in higher education institutions. Analyzing a rich dataset from Blackbaud Raiser's Edge NXT, spanning 2012 to 2022, the study focuses on donor profiles, including demographics, donation history, and engagement patterns. Key demographic insights include the increasing engagement of younger donors (20-29 age group) and significant contributions from older donors (70-99 age group). Geographical trends are also examined, revealing distinct patterns based on donors' city, state, and ZIP code. The Fine Gaussian SVM model demonstrates moderate discriminatory power, with …