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Expanding The Trypanosoma Brucei Parasite Detection Limit Through Tb177 Gene Detection In Qpcr, Yi Yan Jan 2025

Expanding The Trypanosoma Brucei Parasite Detection Limit Through Tb177 Gene Detection In Qpcr, Yi Yan

Public Health Theses

Trypanosomiasis, caused by protozoan parasites of the Trypanosoma genus, remains a significant health and veterinary burden in sub-Saharan Africa, with Human African Trypanosomiasis (HAT) and Animal African Trypanosomiasis (AAT) posing ongoing threats to underserved populations. Despite advances in therapeutics, the lack of sensitive and scalable diagnostic tools continues to limit early detection, effective disease management, and evaluation of emerging vaccine candidates. Current diagnostic methods such as light microscopy and serological tests frequently fail to detect low levels of parasitemia during the early stages of infection, thereby delaying intervention and increasing the risk of disease progression and transmission.

Our study mainly …


Colorblind Racial Attitudes Mediates The Association Between The Internalization Of Model Minority Myth Attitudes And Tolerance, Talal Ali Jan 2025

Colorblind Racial Attitudes Mediates The Association Between The Internalization Of Model Minority Myth Attitudes And Tolerance, Talal Ali

Senior Honors Theses and Projects

The model minority myth is the belief that Asian Americans are generally more intelligent and more hardworking than other minority groups. Many studies have demonstrated the relationship between belief in the model minority myth and anti-Black sentiment in White Americans. However, there is little literature on the relationship between belief in the model minority myth and anti-Black sentiment in Asian Americans. With this in mind, we plan to determine whether the internalization of the model minority myth in Asian Americans has a relationship with anti- Black sentiment. This relationship is being measured by the IM-4 Scale (which measures the internalization …


Pilot Study: Development Of A Food Delay-Discounting Measure For Individuals With Neurodevelopmental Conditions, Aaron Daniel Schwieterman Jan 2025

Pilot Study: Development Of A Food Delay-Discounting Measure For Individuals With Neurodevelopmental Conditions, Aaron Daniel Schwieterman

Senior Honors Theses and Projects

Individuals with intellectual (NDD) and neurodevelopmental (NDD) conditions experience disproportionately higher rates of obesity (Hsieh et al., 2014; Ptomey et al., 2020). Yet their diet decision-making process has been left out of the current literature. Delay discounting, which reflects the decrease in the subjective value of a reward as the delay to its receipt increases, has been linked to obesity and unhealthy food intake in typically developing adults. However, most existing tasks rely on hypothetical rewards and verbal reasoning, which limit their use with individuals who have cognitive or communication differences. The present pilot study developed and evaluated a novel …


Fairness-Aware And Culturally Adaptive Machine Learning For Predicting Adolescent Substance Use, Stephanie Nworgu Jan 2025

Fairness-Aware And Culturally Adaptive Machine Learning For Predicting Adolescent Substance Use, Stephanie Nworgu

Senior Honors Theses and Projects

Early initiation of substance use during adolescence poses significant risks to long-term health, educational attainment, and social outcomes, making early identification a critical public health priority. Machine learning models have increasingly been used to predict substance use risk; however, many such models do not explicitly examine whether predictive performance differs across demographic groups. This senior project examines the fairness of logistic regression models used to predict first-time alcohol use among adolescents. Using nationally representative survey data from the Youth Risk Behavior Surveillance System (YRBSS), pooled across the 2017, 2019, 2021, and 2023 survey cycles, this study develops logistic regression–based predictive …


The Role Of Leptin In The Regulation Of The Soluble Amyloid Precursor Protein Alpha (Sappa) Levels In Non-Small Cell Lunch Cancer (Nsclc) Cell Media, Benjamin Haddad Jan 2025

The Role Of Leptin In The Regulation Of The Soluble Amyloid Precursor Protein Alpha (Sappa) Levels In Non-Small Cell Lunch Cancer (Nsclc) Cell Media, Benjamin Haddad

Senior Honors Theses and Projects

We previously found that the levels of soluble amyloid precursor protein α (sAPPα) are partly regulated by acetylcholinesterase (AChE) in human non-small cell lung cancer cell lines A549 (p53 wild-type) and H1299 (p53-null). In this study, we hypothesize that sAPPα is partly regulated by leptin, a hormone classically recognized for its anorexigenic role in appetite regulation— yet recently shown to play a role in cancer cell signaling. It was observed that cells treated with leptin exhibited greater concentrations of sAPPα and lower concentrations of Aβ40/42 in the media compared to those of cells left untreated. An opposite effect was observed …


A Review Of Infrared Thermography Applications For Civil Infrastructure, Prabal Shrestha, Onur Avci, Sahabeddin Rifai, Feras Abla, Michael Seek, Karl Barth, Udaya Halabe Jan 2025

A Review Of Infrared Thermography Applications For Civil Infrastructure, Prabal Shrestha, Onur Avci, Sahabeddin Rifai, Feras Abla, Michael Seek, Karl Barth, Udaya Halabe

Engineering Technology Faculty Publications

Civil infrastructure is continuously subject to aging and deterioration due to multiple factors, which lead to a decline in performance and impact structural health. Accumulated damage on structures increases operational costs and poses significant risks to public safety. Effective maintenance, repair, and rehabilitation strategies are needed to ensure civil infrastructure’s overall safety and reliability. Non-Destructive Evaluation (NDE) methods are utilized to assess latent damage and provide decision-makers with real-time information for mitigating hazards. Within the last decade, there has been a significant increase in the research and development of innovative NDE techniques to improve data processing and promote efficient and …


Evaluating The Effectiveness Of Stay-In-Place Forms To Improve The Tosional Stability Of Box Beam Bridges During Erection, Karl E. Barth, Michael W. Seek, Gregory K. Michaelson, Dimitra Pyrialakou, Brook T. Woldegabriel Jan 2025

Evaluating The Effectiveness Of Stay-In-Place Forms To Improve The Tosional Stability Of Box Beam Bridges During Erection, Karl E. Barth, Michael W. Seek, Gregory K. Michaelson, Dimitra Pyrialakou, Brook T. Woldegabriel

Engineering Technology Faculty Publications

Cold-formed tub girders provide an effective steel solution for short-span bridges. The girders are often delivered with an open top with stay-in-place forms installed on site. Walkways may be installed to the side of the girder that can induce significant torsion rotations in the open cross section. Full scale tests on girder specimens have shown that installing one or two panels of stay in place forms at the ends of the girder can significantly reduce the torsion rotation of the girder by providing warping resistance. Cantilever tests on the stay in place forms are performed to investigate the influence of …


Social Media, Populism, And Militant Democracy: An Argument For A Change In First Amendment Doctrine, Arvid Kerschnitzki Jan 2025

Social Media, Populism, And Militant Democracy: An Argument For A Change In First Amendment Doctrine, Arvid Kerschnitzki

Chapman Law Review

The First Amendment is often hailed as the cornerstone of American self-government, but the digital age has transformed the public discourse it was meant to protect. Social media platforms, once envisioned as a modern marketplace of ideas, now amplify misinformation, entrench echo chambers, and enable mass manipulation, threatening the democratic ideal of an informed citizenry.

While the current First Amendment doctrine rightly emphasizes the importance of public discourse, that discourse must be inclusive, rational, and reliable to serve its democratic function. Drawing on the concept of militant democracy, this Article argues that contemporary doctrine has lost sight of free speech’s …


A Wall Of Smoke: Understanding The Drivers Of The June 2023 Canadian Wildfire Smoke Event For New York City, Gregory S. Randazzo Jan 2025

A Wall Of Smoke: Understanding The Drivers Of The June 2023 Canadian Wildfire Smoke Event For New York City, Gregory S. Randazzo

Dissertations and Theses

The 2023 Canadian wildfire season was notable for its extent and the dense smoke it produced. Motivated by the resulting air quality impacts in the New York City region, we explore how the total particulate matter output from the Quebec fires influenced PM2.5 concentrations downstream in New York City. Using injection height data from the Regional Advanced Baseline Imager + VIIRS Emissions dataset, we relate the tropospheric injection heights of the fires with the broader synoptic context and surface PM2.5 concentrations. Using data from the NYS Mesonet Profiler Network, radiosondes, and ERA5 reanalysis, we document the connection between an anomalous …


Using Trace Gas Measurements As A Transport Diagnostic For Tropical Convection: A Combined Model And Observation Study, Albane Hoxha Jan 2025

Using Trace Gas Measurements As A Transport Diagnostic For Tropical Convection: A Combined Model And Observation Study, Albane Hoxha

Dissertations and Theses

No abstract provided.


Peacekeeping In Sierra Leone And Mali, Ishaka Kondeh Jan 2025

Peacekeeping In Sierra Leone And Mali, Ishaka Kondeh

Dissertations and Theses

This thesis examines the effectiveness of peacekeeping missions in promoting democracy, protecting human rights, and implementing Disarmament, Demobilization, and Reintegration (DDR) programs in post-conflict Sierra Leone and Mali. By analyzing the United Nations Mission in Sierra Leone (UNAMSIL) and the United Nations Multidimensional Integrated Stabilization Mission in Mali (MINUSMA), this research explores the impact of these missions on Mali still in conflict and long-term peacebuilding. The study focuses on three critical areas: supporting democratic governance, ensuring human rights protections, and successfully reintegrating former combatants into society. Through a comparative approach, this research analyzes why some peacekeeping missions succeed and then …


Examining Drug Policy In Portugal And Greece, Collin Fernandes Jan 2025

Examining Drug Policy In Portugal And Greece, Collin Fernandes

Dissertations and Theses

This thesis examines the divergent drug policies implemented in Portugal and Greece, analyzing why Portugal's comprehensive decriminalization model has been more successful than Greece's partial approach. Since 2001, Portugal has pioneered a drug policy that decriminalizes all drugs for personal use while investing in harm reduction services, rehabilitation, and social reintegration. In contrast, Greece maintained criminalization while implementing more limited harm reduction measures, particularly through OKANA (the Organization Against Drugs). The research highlights how economic factors, particularly the 2008 financial crisis and austerity measures, negatively affected both countries' programs but hit Greece's initiatives with greater severity. Portugal's programs have remained …


Soviet-American Relations During The Cold War: What Policies And Circumstances Conspired To Unravel The Soviet Empire?, John W. Krey Jan 2025

Soviet-American Relations During The Cold War: What Policies And Circumstances Conspired To Unravel The Soviet Empire?, John W. Krey

Dissertations and Theses

The two victorious superpowers of World War II – America and the Soviet Union – conceived and implemented unilateral foreign policies amid an atmosphere of intense hostility and suspicion of each other’s international intentions. Regardless of Moscow’s acquiescence in joining the United Nations and resolving a host of disputes (for example, the Security Council veto) regarding the establishment and operation of the same organization, it threatened to disequilibrate power relations between the US and the Soviet Union in the immediate aftermath of the second world war, which convinced Washington to develop the containment policy, a defensive realist posture for repelling …


Beyond The Threshold Of Protection: Examining Non-Refoulement's Erosion In Contemporary Refugee Law Through The Eu-Turkey Agreement, Aya Osman Jan 2025

Beyond The Threshold Of Protection: Examining Non-Refoulement's Erosion In Contemporary Refugee Law Through The Eu-Turkey Agreement, Aya Osman

Dissertations and Theses

This thesis examines the contemporary relevance and practical implementation of the principle of non-refoulement as established in the 1951 Refugee Convention. While this fundamental principle of international refugee law prohibits the return of individuals to countries where they face persecution, torture, or human rights violations, its widespread violation by state parties raises critical questions about its continued effectiveness and the broader validity of the Convention's framework in today's global context. Through a methodological approach combining legal analysis and case studies of state practices, this paper investigates whether the 1951 framework remains valid and in effect when addressing refugee and immigration …


The Rise Of China: Economic Expansion, Military Modification And The Belt And Road Initiative, Felix Padilla Jan 2025

The Rise Of China: Economic Expansion, Military Modification And The Belt And Road Initiative, Felix Padilla

Dissertations and Theses

In order to analyze China’s rise in power, we have to examine how China has achieved this growth. We need to observe their domestic reforms, international initiatives like the Belt and Road Initiative (BRI), and strategic military advancements. This thesis focuses on China’s economic integration, market reforms and military modernization. The thesis uncovers the effects of this rise on global governance and power balances, especially in trade, security, and geopolitics. I analyze China's vision of a multipolar world and how it contrasts with the current global order and how this fuels rivalry with the U.S. and other powers. China's rise …


The Transformative Power Of An Ethic Of Care In Patricia Piccinini’S Mythic Posthuman Offspring, Keely Parrish Jan 2025

The Transformative Power Of An Ethic Of Care In Patricia Piccinini’S Mythic Posthuman Offspring, Keely Parrish

Dissertations and Theses

This thesis examines the contemporary artist Patricia Piccinini and her posthuman hybrid creations within the context of a feminist ethic of care. Largely referring to scholarship by the political scientist Joan C. Tronto, I argue that Piccinini expands the definition of an ethic of care to include non-human entities as well as human ones. The four phases of care identified by Tronto will serve to outline the encounter between the audience and Piccinini’s work to see how humans and non-humans (1) care about, (2) take care of, (3) give care and (4) receive care from each other, as well as …


Living By The Sword: Religiosity And The Terrorist Subculture Of Russian Revolutionaries, 1904-1910, Gregory I. Mcevoy Jan 2025

Living By The Sword: Religiosity And The Terrorist Subculture Of Russian Revolutionaries, 1904-1910, Gregory I. Mcevoy

Dissertations and Theses

The Marxist dictum of “religion is the opiate of the masses” has led to a prevailing assumption in scholarship that the socialist movements of the early twentieth century have been inherently atheistic. Religion is often associated as a remnant of old, antiquated society and incompatible with the claimed modernity of socialist progress. This assumption has led to overlooking the religiosity within certain radical movements and revolutionary culture at large. Scholarship on the political underground in Tsarist Russia has, thus far, perpetuated this impression. While it is the true that the Bolsheviks and Leninist Social Democrats rejected religion as obscurantist and …


Posters, Propaganda, & Bloody Saturdays: Making China Christian: How Media & Missionaries Made China Christian, Kristy Lee Jan 2025

Posters, Propaganda, & Bloody Saturdays: Making China Christian: How Media & Missionaries Made China Christian, Kristy Lee

Dissertations and Theses

This thesis investigates the role of religious groups and media in influencing the public perception of Chiang Kai-shek and the Kuomintang during the Second Sino-Japanese War.


Defining ‘Un-Americanism’ In Culture And Art: The Dies Committee’S Investigation Of The Federal Theatre Project, Matthew G. Summers Jan 2025

Defining ‘Un-Americanism’ In Culture And Art: The Dies Committee’S Investigation Of The Federal Theatre Project, Matthew G. Summers

Dissertations and Theses

This thesis explores the House Un-American Activities Committee’s (HUAC) expansive definition of ‘Un-Americanism’ through the body’s 1938 investigation of the Federal Theatre Project (FTP). The committee, then known as the Dies Committee after its chairman Martin Dies (D-TX), publicly presented the hearings as an attempt to root out communism in a deeply compromised government program. And indeed the FTP, an ambitious New Deal Program to provide work for unemployed professionals in the theatre, had an undoubtedly leftist bent. However, the hearings were consistently focused on the project's progressive stances on issues of race and gender, and effectively exposed the underlying …


The Sand Creek Massacre And The History Of Greater Reconstruction In The American West, Anna E. Plotnick Jan 2025

The Sand Creek Massacre And The History Of Greater Reconstruction In The American West, Anna E. Plotnick

Dissertations and Theses

In the traditional U.S. historical narrative, the Civil War & Reconstruction era is a North vs. South story. Nevertheless, the era of western expansion, a central theme throughout the nineteenth century, has no contingent place within this traditional narrative. Meanwhile, the history of the American West and its diverse peoples appears in many textbooks as an unrelated albeit contemporaneous narrative. Separated by geographical regions, historians often do not examine these concurrent histories. However, many of these historical events and actors were interconnected. As I am interested in understanding the Reconstruction era’s national impact, I intend to explore how Reconstruction policies …


Sticky Valuations, Systemic Risks: Quantifying The Denominator Effect Of Private Equity Holdings In U.S. Public Pensions, Rutvij Thakkar Jan 2025

Sticky Valuations, Systemic Risks: Quantifying The Denominator Effect Of Private Equity Holdings In U.S. Public Pensions, Rutvij Thakkar

CMC Senior Theses

U.S. public pension systems have increasingly adopted the "Yale Model," shifting assets under management into private equity to capture excess returns. However, the valuation asymmetry between marked-to-market public equities and smoothed private net asset values creates a mechanical denominator effect during market downturns. This thesis quantifies this passive allocation drift using a fixed-effects panel regression of 2,706 observations from 182 U.S. public pension plans between 2005 and 2024. I find that a 10 percentage point decline in public equity returns mechanically increases private equity allocation by 50.5 basis points, an effect that amplifies to 55 basis points during systemic crises. …


Isolating Confounding Abiotic And Biotic Effects On The Phenotype On Physa Acuta Snails, Ashley M. Bauer Jan 2025

Isolating Confounding Abiotic And Biotic Effects On The Phenotype On Physa Acuta Snails, Ashley M. Bauer

Theses and Dissertations

Organisms match their phenotypes to prevailing environmental conditions leading to habitat specific polymorphisms. Polymorphisms arise from genetic divergence, phenotypic plasticity, or a combination of both processes. I examined the presence of habitat-specific polymorphism in Physa acuta snails collected from three streams and their corresponding downstream reservoir. In lotic systems shells were rotund with larger apertures, while those from lentic systems were more elongate with smaller apertures. In a reciprocal transplant lab experiment that crossed flow regime and crayfish predator cues, I tested for the underlying mechanisms responsible for the observed phenotypic differences. I found no evidence for plasticity in relation …


Rural Realities Unveiled: Non-Certified Teachers’ Experiences And Perceptions Of Scripted Literacy Curriculum In K-5 Classrooms, Amillia Woolfork Jan 2025

Rural Realities Unveiled: Non-Certified Teachers’ Experiences And Perceptions Of Scripted Literacy Curriculum In K-5 Classrooms, Amillia Woolfork

Theses and Dissertations

The persistent shortage of certified teachers in rural school districts has led to an increased reliance on non-certified teachers NCTs to deliver literacy instruction. To support these educators, many districts have implemented scripted curricula, which provide structured lessons and instructional materials. However, limited research exists on the experiences of NCTs using scripted curricula and their impact on their teaching practices and self-efficacy. This qualitative exploratory case study examines the perceptions and lived experiences of non-certified literacy teachers in rural elementary schools who utilize scripted curricula. Guided by Bandura’s Self-Efficacy Theory and Kolb’s Experiential Learning Theory, this study examined how NCTs …


Exploring Advancement Department Staff Perspectives On Strategic Communication And Philanthropic Donor Giving At Public Universities, Miranda Hodges Jan 2025

Exploring Advancement Department Staff Perspectives On Strategic Communication And Philanthropic Donor Giving At Public Universities, Miranda Hodges

Theses and Dissertations

This qualitative study investigated advancement staff perspectives on how donor communication impacts philanthropic giving at higher education institutions. The purpose of this study was to identify the communication practices that are most influential for philanthropic donor giving. While prior research has examined university marketing efforts, why alumni give back, and how affinity for a university compels donors to give, there is a research gap in how strategic communication impacts donor behavior at public universities. Eight university advancement staff members (N=8) from public universities across the Southeast United States were selected through purposive sampling and interviewed via semi-structured interviews. After interviews, …


The Liminal South : Explorations Of Black Time, Space, And Memory, Kennedy Buckner Jan 2025

The Liminal South : Explorations Of Black Time, Space, And Memory, Kennedy Buckner

Theses and Dissertations

This project is composed of two analytical essays and a three-dimensional art exhibition that tangibly extract and display the ways I view the U.S. American south and my interactions with it. Inspired by the narrative photography of Carrie Mae Weems and her “Kitchen Table Series,” the project focuses on multiple generations of my own family in order to document my family's experiences in the south while theorizing how our experiences provide greater historical understanding of southern black communities over time. The first essay theorizes time, space, and memory in Toni Morrison's narrative novel Song of Solomon, with a focus on …


Seagrassnet Monitoring In The Great Bay Estuary, Nh/Me Field Season 2023, Kalle Matso, Lara Martin, Trevor Mattera, Thomas Gregory, David M. Burdick, Christopher Thomas Whitney Jan 2025

Seagrassnet Monitoring In The Great Bay Estuary, Nh/Me Field Season 2023, Kalle Matso, Lara Martin, Trevor Mattera, Thomas Gregory, David M. Burdick, Christopher Thomas Whitney

PREP Reports & Publications

No abstract provided.


Comparative Analysis Of Lipid Accumulation And Antioxidant Responses In Masld And Control Ipsc-Heps, Anna Werts Jan 2025

Comparative Analysis Of Lipid Accumulation And Antioxidant Responses In Masld And Control Ipsc-Heps, Anna Werts

CMC Senior Theses

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a prevalent liver condition characterized by lipid accumulation and associated inflammation, driven by genetic, environmental, and metabolic factors. Much is still unknown about the mechanisms of the disease, and research on this is important for advancing effective treatments. This study investigated lipid accumulation and oxidative stress responses to varying concentrations of oleic acid (OA) and palmitic acid (PA) in induced pluripotent stem cell-derived hepatocytes (iPSC-Heps) from MASLD and healthy donors. BODIPY staining revealed that MASLD iPSC-Heps exhibit significantly higher lipid accumulation than controls, especially under prolonged OA and PA exposure. Additionally, PLIN2 expression …


Trade Tensions And Consumer Decisions: Evidence From Taxable Sales During The 2018 Us-China Trade War, Eddie Wei Jan 2025

Trade Tensions And Consumer Decisions: Evidence From Taxable Sales During The 2018 Us-China Trade War, Eddie Wei

CMC Senior Theses

This paper examines the consumption response to the 2018 US-China trade war. While prior research has largely focused on economic outcomes such as export values, income, and employment, trade policies may also have salient distributional consequences for consumption. On one hand, import tariffs may boost well-being in regions with greater employment in protected sectors, such as manufacturing. On the other hand, retaliatory tariffs may raise prices overall and depress consumption in areas more reliant on the Chinese market, such as agriculture. To explore these dynamics, I construct a novel dataset of county-level taxable sales, capturing both household and business spending. …


The Sword, The Purse, And The Pen: The Constitutional Conundrum Of Impoundment, William N. Chance Jan 2025

The Sword, The Purse, And The Pen: The Constitutional Conundrum Of Impoundment, William N. Chance

CMC Senior Theses

This Thesis explores the constitutional conundrum of executive impoundment, the practice by which the President of the United States withholds or delays the expenditure of funds appropriated by Congress. Although impoundment has deep historical roots dating back to the Constitution’s Framers, its modern use raises profound questions regarding our separation of powers. This Thesis establishes a functional framework that distinguishes between “routine” impoundments, which promote administrative efficiency, and “policy” impoundments, which may undermine congressional intent. Furthermore, after tracing the development of impoundment from the early Republic through the Nixon Administration and the passage of the Impoundment Control Act of 1974, …


Preferences For Enhanced Seasonal Weather And Climate Services Among Maize Farmers In Zimbabwe: A Choice Experiment Analysis, Joseph Manzvera, Kwabena \ Asomanin Anaman, Akwasi Mensah-Bonsu, Alfred Barimah Jan 2025

Preferences For Enhanced Seasonal Weather And Climate Services Among Maize Farmers In Zimbabwe: A Choice Experiment Analysis, Joseph Manzvera, Kwabena \ Asomanin Anaman, Akwasi Mensah-Bonsu, Alfred Barimah

All Rsif Scholars' Publications

Using a discrete choice experiment, this article analyzed maize farmers' stated preferences for seasonal weather forecast attributes in Zimbabwe. Specifically, the study assessed the most preferred attributes of modern seasonal weather forecasts to guide investment priorities. The mixed logit model, which accounts for taste heterogeneity, was employed to analyze the data. The results show that maize farmers place positive utility on downscaling forecasts to the village level, bundling with agronomic advisory information, and a long lead time of 6 months ahead of the onset of the rainy season. Farmers are willing to pay 1.40 United States dollars (US$) for downscaling …