Digital Commons Network^™

Evaluating The World Health Organization's Hearts Model For Hypertension And Diabetes Management: A Pilot Implementation Study In Guatemala, Irmgardt Alicia Wellmann, Luis Fernando Ayala, Taryn M Valley, Vilma Irazola, Mark D Huffman, Michele Heisler, Peter Rohloff, Rocío Donis, Eduardo Palacios, Manuel Ramírez-Zea, David Flood

2020-Current year OA Pubs

BACKGROUND: The World Health Organization HEARTS Technical Package is a widely implemented global initiative to improve the primary care management of cardiovascular disease risk factors. The study's objective is to report outcomes from a pilot implementation trial of integrated hypertension and diabetes management based on the HEARTS model in Guatemala.

METHODS: We conducted a single-arm pilot implementation trial over six months from October 2023 to May 2024 in 11 Guatemalan Ministry of Health primary care facilities in two districts. The pilot evaluated a package of five HEARTS-aligned implementation strategies to improve the pharmacological treatment of hypertension and diabetes. The primary …

Non-Achievement Of Low-Density Lipoprotein Cholesterol Goal And Related Factors Among Elderly Outpatients In Viet Nam: A Cross-Sectional Study, Dung Si Ho, Teo Van Le, Hung Cao Dinh, Thach Nguyen, Duc Khiem Ngo, Cong Duc Nguyen

School of Medicine Publications

Introduction: Dyslipidemia, particularly elevated serum low-density lipoprotein cholesterol (LDL-C), plays a crucial role in the development and progression of atherosclerosis. This study aimed to determine the rate of LDL-C non-achievement according to the European Society of Cardiology/European Atherosclerosis Society 2019 (ESC/EAS 2019) guidelines and related factors in the elderly.

Methods: This was a cross-sectional study involving 555 individuals (age 69.30 ± 6.54, male/female ratio 4.55/1) in an outpatient clinic in Ca Mau province from October 2020 to June 2021. Demographic information, medical history, clinical characteristics, and tested cholesterol, including LDL-C level, were collected to assess cardiovascular risk and determine factors …

6,7-Dichloro-1h-Indole-2,3-Dione-3-Oxime Functions As A Superagonist For The Intermediate-Conductance Ca2+-Activated K+ Channel KCa3.1, Joshua A. Nasburg, Kyle C. Rouen, Connor J. Dietrich, Heesung Shim, Miao Zhang, Igor Vorobyov, Heike Wulff

Pharmacy Faculty Articles and Research

NS309 (6,7-dichloro-1H-indole-2,3-dione-3-oxime) is widely used as a pharmacological tool to increase the activity of small- and intermediate-conductance calcium-activated potassium channels. NS309 is assumed to function as a positive allosteric gating modulator. However, its binding site and the molecular details of its action remain unknown. Here, we show that NS309 has a profound effect on the calcium-dependent gating of the intermediate-conductance Ca2+-activated K+ channel KCa3.1. In inside-out experiments, 10 μM NS309 shifted the calcium EC50 from 430 to 31 nM. In whole-cell experiments, changing free intracellular calcium from 250 nM to 3 μM decreased the EC50 of …

Nutritional Supplements: Necessity Or Overhyped?, Harpreet Kour

Indian Journal of Health Sciences and Biomedical Research KLEU

No abstract provided.

Allergic Rhinitis And Cancer – Is Immunocontainment The Way Forward?, Rajesh Radhakrishna Havaldar

Indian Journal of Health Sciences and Biomedical Research KLEU

No abstract provided.

The Role Of Vitamin D In Fracture Prevention Among The Elderly, Shrihari L. Kulkarni

Indian Journal of Health Sciences and Biomedical Research KLEU

No abstract provided.

Tubular Adenomas Of The Breast: Case Report And Literature Review, Rushang Dave, Darshit Kateshiya, Hiren Gajera, Riddhi Parsana

Indian Journal of Health Sciences and Biomedical Research KLEU

Tubular adenomas in the breast are uncommon neoplasms. Few examples have been documented. In women of reproductive age, the tumors are typically described as palpable, well-circumscribed lumps. Fibroadenomas are the most common diagnosis, both clinically and radiographically. For diagnosis and to stop the growth from continuing, surgery is necessary. Histopathology of tubular adenoma shows bilayer tubules with an intervening stroma. It is often a small, benign breast tumor that may be nodular. We describe rare tumor cases here that had peculiar appearances.

Title-Rare Case Of Retroperitoneal Colon Perforation In Advanced Squamous Cell Carcinoma Of Kidney, Kumar Vinchurkar, Shekhargouda Deshetti, Imtiaz Ahmed

Indian Journal of Health Sciences and Biomedical Research KLEU

Squamous cell carcinoma (SCC) of the renal pelvis is an uncommon tumor typically linked to chronic renal stone disease. This tumor is inherently aggressive and generally associated with a poor prognosis. We present a case involving a patient with retroperitoneal descending colon perforation in advanced squamous cell carcinoma of kidney probably secondary to radiation. Radiation-induced gastrointestinal perforation necessitates emergency surgery, and there is a lack of high-quality evidence to support the effectiveness of any preventive measures. In this review, we provide an overview of the clinical manifestations, risk factors, mechanisms, and treatments associated with radiation-induced gastrointestinal perforation. A thorough treatment …

Fifteen-Kilogram Giant Retroperitoneal Liposarcoma Treated With Multiorgan Resection: A Case Report And Review Of Literature, Rashpal Singh, Nitish Kumar, Deepayan Mali, Anchana Gulati

Indian Journal of Health Sciences and Biomedical Research KLEU

No abstract provided.

A Rare Case Of Growth Delayed Due To Pituitary Stalk Interruption Syndrome: A Case Report, Prithviraj Ram Desai, Kirthi Rajeev, Bhargav P Sawant Dessai

Indian Journal of Health Sciences and Biomedical Research KLEU

Pituitary stalk interruption syndrome is extremely uncommon, with a 0.5 in 1 million estimated frequency. Growth retardation is typically caused by a lack of growth hormones, which is usually present in the first ten years of life. The case in question involves a 9-year-old boy who presented to OPD with a growth delay. Further investigations supported the diagnosis of a posterior pituitary hormone deficiency based on the biochemical profile. His brain was scanned using magnetic resonance imaging (MRI), which revealed a T1 hyperintense concentration at the median eminence in the middle of his brain but no signs of the anterior …

First Outbreak Of Dengue In Dhanpur Of Sonamura, Sepahijala District Of Tripura: A Report, Taranga Reang, Sibabrata Bhattacharjee, Parimal Sarkar, Tapash Ghosh

Indian Journal of Health Sciences and Biomedical Research KLEU

No abstract provided.

Prevalence And Determinants Of Contraceptive Use Among Married Women In A Rural Area Of Tamilnadu –A Cross Sectional Study, M. Mercy, Rajesh Kumar Konduru, Professor Murugan, Anil J. Purty

Indian Journal of Health Sciences and Biomedical Research KLEU

Background: Currently the prevalence of family planning use had dropped from 61.4% in the year 2005-2006(NFHS-3) to 53.2% in the year 2015-2016(NFHS-4). Hence this study was done to ascertain the prevalence and determinants of contraceptive use among married women .

Objectives: To determine the prevalence and determinants of contraceptive use among married women in reproductive age group of 18-45 years.

Methodology: It was a cross sectional study in the Rural Health Training Centre (RHTC) of Department of Community Medicine in Pondicherry Institute of Medical Sciences. Five villages were selected randomly and the study participants were questioned using a pretested and …

A Longitudinal Study Of High-Risk Pregnancy And Its Outcome Among Antenatal Women Residing In An Urban Field Practice Area, A. B. Safeena, J. M. Girija, Anjali Patil

Indian Journal of Health Sciences and Biomedical Research KLEU

Background: High-risk pregnancies pose significant challenges to maternal and foetal health, necessitating a comprehensive understanding of the associated demographic, socio-economic, medical, and obstetric factors This study aimed to study the outcome of high-risk pregnancies

Methodology: A longitudinal study was conducted among 130 pregnant women at two Urban Health Centres. Data was collected on demographic, socio-demographic and obstetric characteristics. Pradhan Mantri Surakshit Matritva Abhiyan (PMSMA) guidelines was used to identify the high-risk women and their outcome (maternal and foetal) were noted.

Result: Mean age of participants was 25.86 years (SD = 3.9). Majority belonged to 20-24 years (40.8%) age group and …

Referral And Consultation At The Adult Endocrinology Outpatient Clinic: A Facility-Based Cross-Sectional Study, Taoreed Adegoke, Iretenevesho Yvonne Obaitan, Oluwatosin Deborah Kuku, Donald Worlumati Nlerum, Gloria Agbo-Onche

Indian Journal of Health Sciences and Biomedical Research KLEU

Background: Knowledge of the pattern of referrals to the Endocrinologist helps in optimizing care and allocating resources. However, there is a dearth of information about the endocrinology outpatient service in a private tertiary setting in sub-Saharan Africa. The study aims to bridge this gap.

Methodology: It is a cross-sectional study. New referrals to an endocrinology clinic were analyzed over 16 months, and the outcomes of interest included the sociodemographic, waiting time, sources of referral, and diagnoses.

Results: The final sample size was 122. The age ranged between 18 and 87 years, and the median age was 55 years. Among the …

Clinico-Radiological Profile And Associated Risk Factors Of Spontaneous Intra-Cerebral Hemorrhagic Stroke In Haryana, Sugam Null, Rakesh Tank, Anurag Ambroz Singh, Suraj Chawla, Vikram Singh Tanwar, Shobhit Singh, Karishma Null, Pranav Sharma

Indian Journal of Health Sciences and Biomedical Research KLEU

Introduction: Stroke is a group of clinical manifestations resulting from cerebral ischemia or intracranial hemorrhage. Hemorrhagic strokes account for 15% of all cases of acute strokes. Hemorrhagic strokes are classified into intra-cerebral hemorrhage and subarachnoid hemorrhage. Clinical manifestation and epidemiological characteristics vary based on the specific location and severity of the lesions. Several risk factors have been identified for this condition.

Objective/Aim: To evaluate the risk factors and clinic-radiological characteristics of spontaneous intra-cerebral hemorrhagic stroke.

Methodology: This cross-sectional study was carried in a tertiary care institute of southern part of Haryana. A total of 100 study subjects with intra-cerebral haemorrhage …

Cardiotocography And Whatsapp As A Combination Of Tools For Early Reporting And Referring High Risk Pregnancies In Rural Health Setups Of Bhanpur Kalan, Jaipur, Rajasthan, Anita Simlot, Monika Rathore, Chetram Meena, Mahendra Thakor, Supriya Chouhan, S. S. Mohanty

Indian Journal of Health Sciences and Biomedical Research KLEU

Context: Cardiotocography (CTG) records and monitors the fetal heart rate (FHR) electronically. This is done to assess the fetal health and look for symptoms of intrapartum hypoxia. Timely identification and early detection of fetuses at risk is one way of reducing pregnancy-related adverse outcomes.

Aims: The study aimed to screen and detect high-risk pregnancies in rural populations with probable fetal distress to ensure timely intervention and referral to tertiary health care centers through the combination of CTG and WhatsApp.

METHODOLOGY: This three-year prospective study was carried out at the Community Health Centre in Bhanpur Kalan, India. Women who had …

A Comprehensive Study On Factors Leading To Nonadherence To Inhaler Therapy Among Chronic Obstructive Pulmonary Disease Patients In A Tertiary Care Setting, Shiv Kumar Verma, Abhishek Chandra, Manisha Das Gupta, Manoj Kumar Panday, Rinki Kumari

Indian Journal of Health Sciences and Biomedical Research KLEU

INTRODUCTION: Medication adherence is crucial for managing respiratory diseases. Understanding the factors influencing adherence among patients with respiratory illnesses is essential for improving outcomes and optimizing treatment.

OBJECTIVE: This study explored the multifaceted factors influencing medication adherence among patients with respiratory illnesses, focusing on patient characteristics, clinical factors, beliefs about medications, and reasons for irregular medication use.

METHODOLOGY: A cross-sectional design assessed medication adherence and beliefs in chronic obstructive pulmonary disease (COPD) patients through questionnaires. Patient demographics and clinical characteristics were analyzed to understand their impact on adherence.

STATISTICAL ANALYSIS USED: Medication adherence was measured using the Adherence to …

Socio-Demographic And Clinico-Obstetric Profile Of Human Immunodeficiency Virus And Hepatitis B Virus Positive Antenatal Clinic Attendees In A Cottage Hospital In Nigeria: A Five-Year Retrospective Study, Alphonsus Rukevwe Isara, Akinwumi Fajola, Olusola Peter Aduloju, Rebecca Ogbimi

Indian Journal of Health Sciences and Biomedical Research KLEU

BACKGROUND: Sexually transmitted infections especially HIV and HBV significantly contribute to morbidity and mortality in pregnant women and their children especially in sub-Saharan Africa.

OBJECTIVE: This study reviewed the socio-demographic, clinical and obstetric profile of HIV and HBV positive pregnant women attending ANC in Obio Cottage Hospital, Port Harcourt, Nigeria.

METHODOLOGY: A retrospective cross-sectional study which reviewed the records of HIV and HBV positive pregnant women who attended ANC clinic from January 2018 to December 2022. Data was analyzed using SPSS version 26.

RESULTS: A total of 496 pregnant women with a mean age of 31.3 ± 4.9 years …

Leqembi: A Breakthrough In The Treatment Of Alzheimer's Disease: A Mini Report, Saumya Srivastav

Indian Journal of Health Sciences and Biomedical Research KLEU

Lecanemab the humanized IgG1 mAB, is administered intravenously, and binds to Aβ species. It is the only drug among all the currently available treatments that shows a 37\% decline of the abnormal Aβ protein plaques and slowes the loss of the brain function. This drug works in patients in the starting stages of Alzheimer's and dementia. On January 6, 2023, Leqembi got its first FDA approval after its second‑phase clinical trial run by EISAI and Biogen. There are more future studies that are going on and are expected to determine the slowing of not only the Aβ proteins but also …

Music Therapy For Tinnitus, Santosh Kumar Swain

Indian Journal of Health Sciences and Biomedical Research KLEU

Tinnitus is not a disease on its own; rather, it is a symptom that can stem from various underlying conditions. It is characterized as the perception of sound when there is no external source, and it is a prevalent otologic symptom that can be associated with both physical and psychological disorders, significantly impacting the quality of life. Research into the pathophysiology and treatment of tinnitus remains active. There is a growing need for short-term treatments that are minimally invasive yet offer long-lasting relief. Music therapy has emerged as a promising addition to the treatment options. It involves using specially modified …

Visual Artificial Intelligence In Healthcare: A Revolution In Making, Sanjay S. Rao, Punnya. V. Angadi

Indian Journal of Health Sciences and Biomedical Research KLEU

Visual artificial intelligence (AI) is a branch of computer science that teaches robots to understand images and visual information similarly to how humans do. According to the algorithm's development, visual AI allows robots to do more than just perceive; it also allows them to understand and sense the meaning behind images. Because of the enormous progress made in this area, computers are now able to recognize and interpret images more accurately than humans. From managing medical data to enhancing care delivery through AI-assisted diagnosis, visual AI has a broad impact on healthcare. By building devices and tools that can learn, …

The Rise Of Cloned Journals And Websites—A New Wave Of Predatory Deceit?, Nitin Gangane

Indian Journal of Health Sciences and Biomedical Research KLEU

No abstract provided.

Using Graphic Memoirs In A Counseling Children And Adolescent Course: A Phenomenological Arts-Based Study, Timothy Schoonover, Emily Horton, Kailey Bradley

Teaching and Supervision in Counseling

Graphic memoirs in learning environments can facilitate deep educational processes, such as dismantling stigma and biases. There is limited research on the use of graphic memoirs in counselor education. This arts-based phenomenological investigation explored 26 CITs’ experiences with a graphic memoir assignment in a counseling children and adolescent course. There were four themes and one subtheme identified: (a) understanding the Deaf experience and advocacy, (b) professional growth and counseling insights, (c) personal reflection and connection, and (d) educational impact and engagement and one subtheme of using bibliotherapy and creative activities in counseling practice. Discussion and implications for counselor educators are …

Site Supervisor Roles And Responsibilities: Counseling Programs’ Written Expectations, Justin D. Lauka, Amanda Mccarthy, Steven Moody, Minna Yoo

Teaching and Supervision in Counseling

Site supervisors play a vital role in training clinical mental health counseling (CMHC) students during their field work. While clear roles and responsibilities for site supervision is a professional and ethical requirement, the scope of these expectations remains ambiguous. This article provides baseline empirical data on the expectations of sites and site supervisors communicated through field experience handbooks of CACREP-accredited CMHC programs. The authors completed a qualitative content analysis that resulted in three key categories including Site and Site Supervisor Administrative Expectations, Clinical Supervision, and Site/Program Interaction. Implications for counseling programs and future research are discussed.

Effect Of Photovoice On Teaching Research To Counseling Students At Hispanic-Serving Institution, Eunae Han

Teaching and Supervision in Counseling

The current study examined the photovoice project’s effectiveness in teaching research to counselors-in-training at a Hispanic-serving institution. Analysis of 36 pre- and post-survey responses via paired sample t-tests revealed reduced research anxiety and enhanced self-efficacy in research conceptualization, implementation, and presentation. Specific implications for counselor educators and researchers are discussed.

Counselor Educators' Experiences Within The Faculty Microsystem During Gatekeeping, Victor Chang, Deborah J. Rubel

Teaching and Supervision in Counseling

Gatekeeping is a responsibility for all counselor educators (CEs). Little is known about how CEs work with their colleagues to enact gatekeeping in counselor education programs. This grounded theory study explored 12 diverse CEs’ gatekeeping experiences, creating an ecological model of the Faculty Microsystem during gatekeeping that illuminates important conditions, processes, and interactions during gatekeeping in counselor education. Implications for counselor educators and doctoral students on the nature of collaboration during gatekeeping are described.

Grief Education In Accredited Counseling Programs: Tools For Integrating Grief Counseling Concepts Into The Cacrep Foundational Counseling Curriculum, Nicole A. Stargell, Emily T. Smith, Gary W. Mauk

Teaching and Supervision in Counseling

Counselors working in a wide variety of settings should be competent in providing grief counseling. The current CACREP (2024) standards include grief education under lifespan development, but grief education can be woven throughout all eight domains of the foundational counseling curriculum. This article explains the foundational grief counseling concepts of attachment theory, the dual process model of grief, meaning-making theory, and adaptive grieving styles. Included in this article are suggestions for infusing these foundational grief counseling concepts into each of the eight CACREP foundational counseling curriculum areas.

Liberty, Safety, And Misdemeanor Bail, Brandon L. Garrett, Sandra Guerra Thompson, Dottie Carmichael, David Shi, Songman Kang

Florida Law Review

The highest volume of cases in the U.S. criminal system are misdemeanors, and every day, hundreds of thousands of people are detained pretrial in such low-level cases. In policy and in politics, pretrial rules have swung between a focus on protecting constitutional rights and the public safety dangers posed by releasing arrestees. The Supreme Court’s ruling in United States v. Salerno sought to promote a balance between protecting individual due process rights and public safety interests. A central constitutional and pressing policy question is what trade-off exists between pretrial liberty and reoffending. The highest profile jurisdiction to examine that question …

Exploring Neuromyths In Counselor Education: A Neuro-Informed Cognitive Behavioral Therapy Approach, James R. Spears, Natasha Villalobos, Whitney Zahar-Rich, Priscilla R. Prasath, Willie Ray

Teaching and Supervision in Counseling

Although advances in neuroscience validate the therapeutic practices and professional identity of counselors, educators struggle to infuse accurate neuroscience knowledge into the classroom. Utilizing a quasi-experimental, repeated measures design, this study examined the effectiveness of a neuro-informed lecture in reducing neuromyth endorsement among graduate students enrolled in the counseling theories course. Participants (n = 62) completed a demographics questionnaire and identical neuroscience pre- and post-surveys. The intervention group (n = 32) received the lecture-based intervention, while those in the comparison group (n = 30) did not. Results revealed significant improvement in neuroscience knowledge scores for those receiving the lecture (pre: …

“I Feel As Though I Would Not Be Able To Empathize”: Intersectionality And Counselor Intergroup Anxiety, Krista M. Malott, Edward Wahesh, Tina Paone, Amber S. Haley, Alexis Mcclatchy

Teaching and Supervision in Counseling

Researchers applied a thematic analysis in this study to examine the nature of master-level counseling students’ (N = 19) intergroup anxiety (IA), a form of bias characterized by an anxious response to others based on negative views of that person’s identity (Stephan, 2014). Students cited stronger IA reactions toward persons with multiple identity traits (i.e., intersectionality). Traits chosen varied widely, some being dominant (e.g., White, male, able-bodied), and others, minoritized in nature (e.g., Black, Muslim, disabled). Thematic explanations for IA reactions varied, including a fear of client judgement, prior negative experiences with persons of certain traits, limited knowledge of clients’ …