Digital Commons Network^™

Molecular Devolution For Gene Editing: Reverse Directed Evolution Of Cre Recombinase, Giovanna Esposito, Simran Sood, Katie Liu

Bioengineering Senior Theses

The principal objective of this paper is to provide a proof-of-concept of a novel protein engineering method called Molecular Devolution (MD). MD is an evolutionary protein engineering method that reduces the size of enzymes while retaining its functional properties. This paper outlines an MD protocol for Cre Recombinase. Cre Recombinase is an enzyme that is part of the Cre LoxP DNA Recombination System, which is a leading gene editing system widely used in genetic research. This paper outlines a MD approach that was used to miniaturize Cre Recombinase and remove unnecessary complexities, allowing for simpler and more e!cient use in …

Transforming Dredged Sediment Into Reactive Clay: Critical Review Of Calcination, Reactivity, And Sustainable Valorization As Supplementary Cementitious Material, Seongho Han, Sanghwon Wi, Koochul Ji, Keun Hyeok Yang, Farshad Rajabipour, Kamal H. Khayat, Jinyoung Yoon

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Dredged sediment (DS) is generated worldwide in large volumes through routine port and waterway maintenance, yet its disposal presents environmental and economic challenges. Recently, calcined dredged sediment (CDS) has emerged as a supplementary cementitious material (SCM), offering a viable alternative to traditional SCMs, such as fly ash and slag cement. This review synthesizes current knowledge on the physical, chemical, and mineralogical characteristics of raw DS and pretreatment strategies aimed at dewatering, organic matter removal, and contaminant stabilization. The effects of calcination on the production of reactive amorphous aluminosilicates are also discussed. Emphasis is placed on physicochemical changes revealed by experimental …

Low-Carbon Concrete For Sustainable Construction: A Comprehensive Review Of Performance Characteristics, Implementation Challenges, And Decarbonization Pathways, Fazel Azarhomayun, Jingjie Wei, Kamal H. Khayat

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Reducing the carbon footprint of concrete has become a central objective in sustainable construction. Low-carbon concrete (LCC), developed primarily through clinker reduction, supplementary cementitious materials, and alternative binder strategies, offers a promising route for lowering embodied emissions while maintaining the performance requirements of structural concrete. This comprehensive review consolidates the current state of knowledge on LCC, identifies critical research and implementation gaps, and examines its material composition, mixture-design methodologies, performance characteristics, structural applications, implementation challenges, and decarbonization pathways. Single-SCM systems have been reported at clinker-replacement levels approaching 50%, although durability at these replacement levels, particularly carbonation resistance, remains system- and …

Air-Writing Recognition, Gaurang Shukla

Master’s Dissertations

Air-writing is the act of tracing characters or words in free space with a fingertip, recorded by a camera, giving a touch-free input modality for smart displays, augmented and virtual reality, and assistive interfaces. It is difficult because the finger never lifts: connecting strokes join adjacent letters with no pen-up signal to mark boundaries, and the same word varies widely in scale, position, and slant across writers. The WiTA benchmark of Kim et al. provides a large, person-disjoint dataset and a baseline that treats each clip as RGB video, recognised by a spatio-temporal 3D residual network trained with a CTC …

Ontology-Based Decision Support System For Improving Aquaculture Management, Thuy Thi Thu Pham, Phuong Thi Can, Nga Thi Thanh Ha

Journal of Marine Science and Technology–Taiwan

Early detection of shrimp diseases is vital for reducing losses and ensuring sustainable aquaculture. In this study, a novel ontology-driven framework for shrimp disease diagnosis that integrates environmental knowledge with machine learning-based image analysis is proposed. An ontology was constructed from a structured dataset of environmental parameters and farm conditions related to shrimp diseases, which formally represents concepts such as farm characteristics, environmental factors, symptoms, and disease types. Two public shrimp image datasets were subsequently used to train convolutional neural networks (ResNet50 and MobileNetV2) for automated disease classification. The predicted disease labels and confidence scores were mapped onto the ontology. …

Case Study On Operational Performance Improvement By Turbocharger Nozzle-Ring Modification In Shipboard Generators, Jong-Hun Im, Mukyeong Kang, Sang-Deuk Lee

Journal of Marine Science and Technology–Taiwan

Owing to increasingly stringent emission regulations imposed by the International Maritime Organization and rising fuel prices, the demand for enhanced energy efficiency and emission control in marine power systems is increasing. This study presents a case study in which the performance of an aging auxiliary generator is restored by modifying the turbocharger nozzle ring. The vessel, a 12-year-old crude-oil tanker, experienced repeated operational issues with its No. 3 generator. This included elevated exhaust gas temperatures, reduced intake air pressure, and frequent turbocharger surges. To address these challenges, the nozzle-ring blade angle was reduced by approximately 2° using spare components, while …

Towards Sustainable Marine Education: Assessing High School Students’ Understanding Of Conservation Concepts, Cheng-Chieh Chang, Tsuyoshi Sasaki, Ya-Yin Liao, Ling-Ya Hung, Liang-Ting Tsai

Journal of Marine Science and Technology–Taiwan

This study assesses the concepts of marine resource conservation and sustainability among Taiwanese high school students by developing a Chinese version of the Marine Resources Conservation and Sustainability Scale. Grounded in the cognitive, socio-emotional, and behavioral learning objectives outlined in UNESCO’s Education for Sustainable Development Goals (ESDGs), the scale targets students aged 16 to 18 to examine gender differences in marine knowledge and conservation concepts. The scale comprises 31 items across four dimensions: the first section evaluates marine knowledge, while the remaining dimensions utilize a four-point Likert scale to assess cognitive, socio-emotional, and behavioral learning objectives, respectively. The results indicate …

Dynamic Governance Of Transboundary Fisheries Through Deep Learning And High-Frequency Vessel Tracking Data For Climate-Resilient Management: An Application To The East China Sea, Qin Lin, Yaqing Shu, Manel Grifoll, Hongxiang Feng

Journal of Marine Science and Technology–Taiwan

Transboundary fisheries governance is increasingly challenged by jurisdictional conflicts, regulatory asymmetries, and climate-induced stock shifts in fish stocks, especially in contested regions like the East China Sea (ECS). This study capitalizes on China’s high-frequency BeiDou Navigation Satellite System (BDS) data (June 2021–May 2022) to pioneer a CNN-BiLSTM deep learning model to dynamically identify fishing hotspots and evaluate policy effectiveness. By integrating vessel trajectories, environmental variables, and regulatory events, we examine spatiotemporal patterns of fishing effort relative to seasonal bans, extreme weather, and quota systems. Key findings reveal: (1) post-moratorium (September–December) concentration of fishing intensity, peaking in November; (2) significant weather-driven …

Lock Scheduling Decisions And Strategy Optimization Under Operation Interruption Scenarios, Junhe Li, Qiang Zhang, Junpeng Jiang, Jiangchao Bao

Journal of Marine Science and Technology–Taiwan

Locks are critical nodes in inland waterway transportation systems that concentrate vessel traffic between upstream and downstream reaches, making their operations highly sensitive to hydrological conditions. Therefore, disruptions caused by droughts, floods, or routine maintenance can easily trigger congestion. To address this issue, this study systematically examines the interrelationships among the number of ships awaiting passage, scheduling strategies, the trade-off between lock chamber utilization and ship waiting time, the influence of ship entry sequences on user satisfaction, and the combined effects of these factors on overall lock scheduling performance. Based on these analyses, an integrated decision-making model for two-stage ship …

Corrosion Protection Assessment Of Offshore Wind Turbine Substructures Using Beasy Cp Simulation Analysis, Chuan-Yang Wan, Hung-Hua Sheu, Sheng-Yu Wang, Yao-Ming Wang, Wei-De Chen, Ming-Yuan Lin, Hung-Bin Lee

Journal of Marine Science and Technology–Taiwan

This study investigates the corrosion protection assessment of offshore wind turbine substructures established in the waters off Keelung, Taiwan. First, a cathodic protection system for the monopile foundation is designed and established. The Boundary Element Method (BEM) is applied using the BEASY simulation software to develop a 3D geometric model for cathodic protection. In the steel monopile simulation analysis, the exposed marine environment is set based on the sea conditions of the Keelung small boat marina, including parameters such as salinity, resistance, and polarization curves, to establish an effective cathodic protection system for underwater structures. By simulating these parameters, a …

Face-To-Face Versus Distance Education In Competence-Based Maritime Education And Training, Clara Borén, Marcella Castells-Sanabra, Manel Grifoll

Journal of Marine Science and Technology–Taiwan

The COVID-19 pandemic created significant challenges for higher education, with universities being shut down and face-to-face teaching and assessment shifting to an online format. This presented an opportunity to focus on the continuity of learning through distance education, especially in the maritime context, due to the on-board training requirements, and even though five years have passed, this shift has reshaped the education landscape, proving that remote learning has come to stay.

At the Barcelona School of Nautical Studies, we have developed a weather routing software in the framework of distance education and teaching innovation. We conducted a teaching trial alternatively …

A Bibliometric And Visualization Analysis Of Global Giant Clam Research, Chia-Hsiang Chen, Chih-Hsien Chang

Journal of Marine Science and Technology–Taiwan

In this study, bibliometric analysis and visualization tools were used to investigate the academic network and knowledge structure surrounding global giant clam research. A total of 551 relevant publications from the Web of Science database, published from 1900 to 2024, were analyzed. The findings indicate that research on giant clams has experienced considerable growth since 2012, peaking in publication output in 2021. Sixty-six countries were represented in the study sample, with the United States, Australia, China, Singapore, and Japan being the most represented ones. Notably, the rate of international collaboration was only 29%, highlighting a need for additional integrated cross-border …

Design Framework For Polymer Gel Treatments From A Database Of Field Projects, Baojun Bai, Munqith Aldhaheri, Mingzhen Wei

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

This study compiles and analyzes data from over 125 published field projects around the world, covering nearly 900 treated wells. Building on those detailed studies, this paper distills the most important findings into a concise, practical, and actionable framework to guide where in-situ gel treatments should be applied, how they should be designed, and how their outcomes can be evaluated. The proposed workflow guides engineers through five integrated stages: screening appropriate gel types, designing formulation and injection strategies, predicting field response, evaluating treatment performance, and conducting iterative refinement with feedback loops to adjust designs based on observed outcomes. The framework …

The Flight Of The Purdue Owl: An Institutional History, Harry C. Denny, Vicki R. Kennell, Garrett I. Colón

The Founders Series

The Flight of the Purdue OWL: An Institutional History chronicles both the widely known Purdue OWL website and the lesser-known but much-celebrated on-campus writing center. Purdue University is renowned for its world-class STEM curriculum as well as its intercollegiate athletics. The university also receives considerable attention, however, for the OWL website, which is one of the most used educational resources in the world. The on-campus OWL is also a highly regarded collegiate writing center. This book tells the history of how the Purdue OWL grew out of decades of faculty working with students and their desire for a laboratory where …

Building Bridges: The Reference Interview As A Mechanism For Social Capital In School Libraries, Jessica M. Lilly

Learning Hub

Building Bridges: The Reference Interview as a Mechanism for Social Capital in School Libraries

Abstract

School librarians occupy a unique position within schools, interacting across all stakeholder groups and serving as a conduit between students, teachers, administrators, and the broader learning community. This article examines the reference interview not merely as a transactional information-retrieval tool but as a relational practice through which school librarians generate, sustain, and distribute social capital. Drawing on the foundational theories of Putnam (2000), Coleman (1988), and Bourdieu (1986), and on the reference transaction model grounded in Jesse H. Shera's foundational work (Coleman et al., …

2026-06-15 Message From The President, Morehead State University. Office Of The President.

Staff Congress Records

Message sent on June 15, 2026 by the President to the campus community regarding modified hours, upcoming dates of importance, Board of Regents meeting summary, and campus personnel announcements and updates.

Thrivetogether – A Community-Drivenwellness Platform Powered By Ai, Isaac Soto, James Hunter, Ethan Nguyen, Nathan Shimada

Computer Science and Engineering Senior Theses

ThriveTogether is a wellness platform powered by artificial intelligence that is designed to help users create personalized fitness and nutrition plans through a combination of community-shared content and intelligent personalization systems. The platform is developed to support people at all stages of their health journey, including beginners and users with physical limitations, by providing accessible and adaptable wellness guidance. Unlike many existing health applications that rely on generalized advice or costly personalized services, ThriveTogether emphasizes affordability, inclusivity, and practical usability through user-generated recipes, workout plans, and nutrition plans while also enhanced by trusted nutritional sources through a rule-based validation system. …

Heterogeneity Mechanism And More Precise Prediction Of Seafarer Fatigue Based On Group Modelling, Zhiwei Zhao, Anqi Quan, Shuxin He, Lijun Tang, Xinjian Wang, Wessel M.A. Van Leeuwen

Plymouth Business School

Traditional research often treats seafarers as a homogeneous group when exploring the causes of fatigue, neglecting the potential heterogeneity in fatigue mechanisms arising from differences in rank and department. This study systematically analyzes the fatigue driving patterns of four subgroups – Deck Department vs. Engine Department, and Officers vs. Ratings – and constructs high-precision prediction models. Based on questionnaire survey data from 450 seafarers from two Chinese shipping companies, Exploratory Factor Analysis was conducted to extract group-specific factors. Subsequently, Multiple Linear Regression and Backpropagation Neural Network models were established to identify key influencing factors and compare predictive performance. The results …

International Law Situations: Internment Of Belligerent Forces, Raul (Pete) Pedrozo

International Law Studies

This Situation examines the duty of neutral States to detain belligerent warships, their officers, and crews during an international armed conflict. At the outset of the armed conflict between the United States and Iran, Iranian warships sought refuge in India and Sri Lanka following the sinking of the Iranian frigate IRIS Dena. India and Sri Lanka, as neutrals, have a duty to detain those warships and their officers and crews for the duration of the armed conflict and take appropriate measures to render the ships and their personnel incapable of taking to sea during the conflict.

Michigan's Automotive Workforce Transition, Erik Vasilauskas, Michael Horrigan

Upjohn Institute Technical Reports

This report examines how changes in automobile production, specifically the shift from internal-combustion-engine (ICE) vehicles toward hybrids and battery-electric vehicles (BEVs), are likely to affect employment in Michigan’s automotive manufacturing and distribution system over the next decade. The goal is to quantify how many jobs in Michigan depend on the automotive supply chain today, how that employment has evolved since the early 2000s, and how it may change through 2030 under alternative production-and-demand scenarios. The results are intended to inform the workforce planning and community transition strategies of the Michigan Department of Labor and Economic Opportunity’s Community and Worker Economic …

Tuning Ion Mobility And Molecular Confinement In High-Performance Polymer Electrolytes For Energy Storage, Ezzeldien Yousef Muhammed Yousef

Theses and Dissertations

This research addresses the critical energy density limitations of aqueous supercapacitors, which are traditionally constrained by the narrow electrochemical stability window (ESW) of water 1.23 V. By employing two distinct molecular engineering strategies, this study developed high-performance electrolyte systems that significantly extend voltage stability and thermal resilience.

The first system, CsBr@PAM/HA, utilizes a polyacrylamide and hyaluronic acid hydrogel matrix. This system exploits the chaotropic nature of Cs⁺ ions to disrupt the aqueous hydrogen-bonding network, enhancing ionic conductivity to 104 mS cm^-1. Through systematic salt screening, CsBr was identified as the optimal electrolyte, enabling a stable 2.0 V …

“Between Cultural Norms And Economic Survival: Navigating Egyptian Lower And Middle Income Women’S Challenges In The Informal Versus The Formal Work: “A Case Study From Cairo”, Rowan Mahmoud Abdelnazer

Theses and Dissertations

This study investigates the ongoing gender inequities experienced by low and middle-income women in Egypt’s formal and informal labor economy, specifically it is based in Cairo. Although there are many advances made globally on women's rights, yet women still face great challenges such as discrepancies in salary, fewer leadership roles and cultural expectations which put child-bearing duties before professional growth. On the one hand, flexible work for women in developing countries is through informal sector, which makes them vulnerable and serves as a source of their exploitation and insecurity (e.g., lack of social security; workplace hazards), on the other hand, …

Mobilizing Social Capital In Social Entrepreneurship: Strategies, Networks, And Growth In The Egyptian Context, Doaa Alaa

Theses and Dissertations

This thesis examines how social entrepreneurs in Egypt strategically mobilise social capital to access resources, legitimacy, and opportunities within a fragmented and institutionally ambiguous ecosystem. Drawing on qualitative case studies of eight legally registered, mission-driven for-profit enterprises, the study analyses how founders build and leverage offline and online networks through practices such as emotional bonding, community formation, knowledge sharing, symbolic positioning, ecosystem engagement, and digital presence. Through thematic analysis of semi-structured interviews and secondary data, the research identifies a set of relational strategies that function as core mechanisms for entrepreneurial growth in contexts where formal support structures and legal definitions …

Engineering Nanoelectrocatalytic Systems For Co2 And Nitrate Conversion Into Value-Added Chemicals, Abdelrahman Mohamed Abdelmohsen

Theses and Dissertations

The thesis addresses two major related environmental crises: nitrate pollution of water systems and the ever-increasing levels of atmospheric carbon dioxide. Both challenges are closely linked to anthropogenic disturbance of nitrogen and carbon cycles and require sustainable, energy efficient mitigation techniques. In this study, we investigate electrochemical conversion routes as a unified approach to convert these pollutants into value-added compounds: ammonia (NH3) via nitrate reduction (NO3-RR) and ethylene (C2H4) via carbon dioxide reduction (CO2RR). The first half of this work deals with the design and engineering of Cu-Zn alloy electrocatalysts for efficient NO3-RR. Tuning the alloy composition and surface nanostructure …

Re: Comment Letter For Butte Priority Soils Operable Unit (Bpsou), Draft Intermediate (60%) Remedial Design Report, Blacktail Creek Riparian Actions (Dated March 13, 2026), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Gamma Belief Functions And Fuzzy Sets And Application To Combining Predictive Models, Liping Liu

University Research

Extending classic finite frameworks to continuous settings, this paper proposes the concept of gamma belief functions and gamma fuzzy sets. It shows that both the combination of gamma belief functions and the intersection of gamma fuzzy sets remain within the gamma family, enabling their application in combining gamma probability judgments in decision making and gamma regression models in ensemble learning. Using both simulated and real datasets, and under both constant and varying dispersion assumptions, experimental results show that the combined gamma regression models closely approximate the reference models learned from the full datasets, aligning with the objectives of bootstrapping. Notably, …

An Instance Segmentation Based Global Mppt Method For Pv Systems Under Partial Shading Condition, Ehab Ur Rahman, Yousef Mahmoud, Rui Bo

Electrical and Computer Engineering Faculty Research & Creative Works

Partial shading in photovoltaic (PV) systems creates multiple Local Maximum Power Points (LMPPs) on the power-voltage (P-V) curve, causing conventional Maximum Power Point Tracking (MPPT) algorithms to converge prematurely to suboptimal operating points and resulting in significant energy losses. This work proposes a novel vision-based framework that integrates computer vision with Global Maximum Power Point Tracking (GMPPT) to maximize energy harvesting in partially shaded PV systems. The proposed method captures real-time imagery of PV panels to identify cell-level shading patterns, which are subsequently mapped to module electrical characteristics to enable direct analytical estimation of the GMPP voltage. An instance segmentation …

Converting Co2 Into Carbon Nanotubes Via Sequential Co2 Methanation And Methane Pyrolysis, Kaiying Wang, Hao Feng, Ahmad Helaley, Xiaoqing He, Bohong Zhang, Jie Huang, Xinhua Liang

Electrical and Computer Engineering Faculty Research & Creative Works

This study presents a sequential thermochemical catalytic process for converting CO₂ into carbon nanotubes (CNTs), achieving nearly 99% overall CO₂ conversion and solid carbon yields of up to 49% in a single pass. The overall transformation is divided into two thermodynamically favorable steps: (1) low-temperature CO₂ methanation to CH₄ over a sol-gel-prepared Ni87Ce_6.5Zr_6.5-SG catalyst, which achieved >95% CO₂ conversion at 250 °C in a single pass, and (2) subsequent methane pyrolysis to CNTs and H₂ over a Ni@Al₂O₃-IE core-shell catalyst, which showed improved stability and carbon …

Sense Of Belonging Among Undergraduate Students At The American University In Cairo: Demographic Trends, Barriers And Facilitators, Lamiaa M. Mohamed

Theses and Dissertations

A sense of belonging is widely recognized as a key determinant of undergraduate students’ academic success, well-being, and persistence in higher education. However, existing research is largely grounded in Western contexts and often emphasizes institution-level measures, with limited attention to how belonging is experienced and constructed by students in non-Western settings. This study examines undergraduate students’ sense of belonging at the American University in Cairo, focusing on factors that shape belonging and institutional practices that may strengthen it. Using a sequential mixed-methods design, the study examined 87 responses from a quantitative survey adapted from the University Belonging Questionnaire, followed by …

The Effect Of Mwcnt-Oil Impregnation Of Sintered Components On Their Wear And Corrosion Resistance, Maha Khaled Abdelfadeel

Theses and Dissertations

Powder Metallurgy (PM) offers an advantageous route for manufacturing complex and near net-shape components. Their inherent interconnected porosity that promotes the action of self lubrication compromises their structural integrity by creating pathways for corrosion and excessive wear. This research investigates the efficacy of Multi-Walled Carbon Nanotubes (MWCNTs) as a nano additive within the impregnating base oil (SN-150 base oil). An experimental matrix was designed to evaluate the influence of MWCNTs with different concentrations of 0.05, 0.1, and 0.2 wt.% and ultrasonic dispersion with varying sonication times of 30 and 60 minutes on the tribological and electrochemical performance of sintered steel …