Gwtc-4.0: Updating The Gravitational-Wave Transient Catalog With Observations From The First Part Of The Fourth Ligo–Virgo–Kagra Observing Run, A. G. Abac, I. Abouelfettouh, Teviet Creighton, Mario C. Diaz, Raul Alberto Espinosa Perez, J. Lawrence, Francisco Llamas Villarreal, Soma Mukherjee, Volker Quetschke, Miriam Ramos Arevalo, Wenhui Wang

Physics & Astronomy Faculty Publications

Version 4.0 of the Gravitational-Wave Transient Catalog (GWTC-4.0) adds new candidates detected by the LIGO, Virgo, and KAGRA observatories through the first part of the fourth observing run (O4a: 2023 May 24 15:00:00 to 2024 January 16 16:00:00 UTC) and a preceding engineering run. In these new data, we find 128 compact binary coalescence candidates that are identified by at least one of our search algorithms with a probability of astrophysical origin pastro ≥ 0.5 and that are not vetoed during event validation. We also provide detailed source property measurements for 86 of these that have a false-alarm rate …

Open Data From Ligo, Virgo, And Kagra Through The First Part Of The Fourth Observing Run, Ligo Scientific Collaboration, Virgo Collaboration, Kagra Collaboration, Marc Favata, Shoan Ghosh, Rodica Martin

Department of Physics and Astronomy Faculty Scholarship and Creative Works

LIGO, Virgo, and KAGRA form a network of gravitational-wave observatories. Data and analysis results from this network are made publicly available through the Gravitational Wave Open Science Center. This paper describes open data from this network, including the addition of data from the first part of the fourth observing run and selected periods from the preceding engineering run, collected from 2023 May to 2024 January. The public dataset includes calibrated strain time series for each instrument, data from additional channels used for noise subtraction and detector characterization, and analysis data products from version 4.0 of the Gravitational-Wave Transient Catalog.

Gwtc-4.0: Updating The Gravitational-Wave Transient Catalog With Observations From The First Part Of The Fourth Ligo-Virgo-Kagra Observing Run, Ligo Scientific Collaboration, Virgo Collaboration, Kagra Collaboration, Marc Favata, Shoan Ghosh, Rodica Martin

Department of Physics and Astronomy Faculty Scholarship and Creative Works

Version 4.0 of the Gravitational-Wave Transient Catalog (GWTC-4.0) adds new candidates detected by the LIGO, Virgo, and KAGRA observatories through the first part of the fourth observing run (O4a: 2023 May 24 15:00:00 to 2024 January 16 16:00:00 UTC) and a preceding engineering run. In these new data, we find 128 compact binary coalescence candidates that are identified by at least one of our search algorithms with a probability of astrophysical origin p(astro) >= 0.5 and that are not vetoed during event validation. We also provide detailed source property measurements for 86 of these that have a false-alarm rate <1 yr(-1). Based on the inferred component masses, these candidates are consistent with signals from binary black holes (BBHs) and neutron star-black hole binaries (GW230518_125908 and GW230529_181500). Median-inferred component masses of BBHs in the catalog now range from 5.79M(circle dot) (GW230627_015337) to 137M(circle dot) (GW231123_135430), while GW231123_135430 was probably produced by the most massive binary observed in the catalog. For the first time, we have discovered BBH signals with network signal-to-noise ratio exceeding 30, GW230814_230901 and GW231226_101520, enabling high-fidelity studies of the waveforms and astrophysical properties of these systems. Combined with the 90 candidates included in GWTC-3.0, the catalog now contains 218 candidates with p(astro) >= …

Evaluation Of The Oxidative Effect Of Magnetic Resonance Imaging (Mri) On Patients With Type 1 Diabetes, With And Without The Use Of Gadolinium Contrast Agent, Dunya Ali Mustafa

Hilla University College Journal For Medical Science

Background: Type-1 diabetes (T1D) is one of the most prevalent chronic autoimmune diseases, which is characterized by the progressive destruction of insulin-secreting β cells. Evidence indicates that repeated or high-dose exposure to Gadolinium-Based Contrast Agents (GBCAs) during MRI can result in long-term tissue deposition and increased oxidative stress.

Objectives: This study aimed to estimate the oxidative effects of MRI exposure in patients with type-1 diabetes, before and after gadolinium contrast, for different time intervals, using cyclic voltammetry (CV) as an electrochemical analysis tool.

Materials and Methods: The study was performed at Ghazi Al-hariri Hospital in Baghdad, Iraq, from January to …

Association Between Stress And Prolactin Hormone Levels: A Mini-Review, Sara Salah Mahdi, Huda S. Abdulghani

Hilla University College Journal For Medical Science

The physiological functions of prolactin are highly varied, despite the fact that it is most commonly recognized for its participation in the inhibition of reproduction and the regulation of breastfeeding. The conditions known as hyperprolactinemia can have a variety of origins, some of which are physiological and others of which are pathologic. The following are examples of physiological causes: pregnancy, breastfeeding, sleep-related, stimulation of the nipples and sexual orgasm, stimulation or trauma to the chest wall. Another significant physiological factor that contributes to hyperprolactinemia is stress, and the clinical importance of this factor is currently being investigated. This paper aims …

Fragile Hope And The Cultural Life Of Law, Shefali Jain

Socio-Legal Review

This review of Sandhya Fuchs’ Fragile Hope: Seeking Justice for Hate Crimes in India (Stanford University Press 2024) highlights that the book makes a genuinely original ethnographic and conceptual contribution to caste studies and hate crime scholarship. At the same time, the essay argues that there are three limitations to its framework that require greater engagement: the book’s failure to engage with the legal consciousness tradition in socio-legal scholarship, an underdeveloped account of “legal meliorism,” and an unresolved tension between the book’s stated commitment to victim-centred analysis and its ethnographic evidence that frequently discusses movement-level aspirations.

Artificial Intelligence Empowers Particle Physics And Nuclear Physics: From Fundamental Research To Major Applications, Yifang Wang, Yuan He, Yao Huang, Wanbing He, Yi Jiao, Congqiao Li, Ke Li, Beijiang Liu, Yingqi Ma, Yugang Ma, Longgang Pang, Fazhi Qi, Sichao Tan, Chunpeng Wang, Meng Wang, Xiaoheng Xu, Xing Xu, Zhentang Zhao, Yingxun Zhang, Zhengde Zhang, Hongwei Zhao, Lina Zhao

Bulletin of Chinese Academy of Sciences (Chinese Version)

Particle physics and nuclear physics are core foundational disciplines for exploring the fundamental structure of matter and the origin of the universe. The deep integration of artificial intelligence (AI) technology is providing entirely new pathways to address systemic challenges such as the processing of massive amounts of multimodal data, the realization of extreme experimental conditions, bottlenecks in theoretical calculations, and the intelligent control of large-scale scientific facilities. The article systematically elaborates on how AI deeply empowers particle physics and nuclear physics, particularly in major application scenarios such as research on the fundamental structure and origin of mass of matter, the …

Consolidating Chemical Substance Creation Capability Through Ai For Science-Enabled Innovation Equity, Mengchu Jin, Wandong Wang, Jun Zhang, Yi Luo, Zaiku Xie, Jinlong Yang, Jun Jiang

Bulletin of Chinese Academy of Sciences (Chinese Version)

AI for Science (hereinafter referred to as AI4S) is driving profound changes in the paradigm of scientific research. Chemistry, as a central discipline for creating new substances and supporting major national strategic needs such as energy, health, dual carbon goals, advanced manufacturing, and ecological governance, is an important application scenario of AI4S. At present, innovation in the discipline of chemistry by young researchers still faces knowledge silos, capability silos, and resource silos: the accumulation of professional knowledge requires years of effort, frontier knowledge is highly differentiated, experimental capabilities are difficult to reuse, and high-end resources are difficult to coordinate, which …

Artificial Intelligence-Enabled Materials Innovation: Implementation Levels And Strategic Layout, Ziwei Zhao, Fengxiang Zhou, Yanglili Zhou, Can Wang, Pei Zhang, Weihua Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Materials innovation has long been constrained by vast design spaces, complex processing routes, lengthy validation cycles, and difficulties in engineering translation. Traditional research and development models, which mainly rely on accumulated experience, theoretical deduction, and experimental trial and error, have become increasingly insufficient to meet the demand for rapid breakthroughs in critical materials. In recent years, artificial intelligence has been increasingly integrated into materials design, synthesis, and processing, characterization, evaluation, optimization, and application feedback, promoting the transformation of materials innovation from experience-driven exploration to data-driven development and from discrete trial and error to closed-loop optimization. Based on an analysis of …

Artificial Intelligence Empowered Biological Research: Paradigm Shifts, Application Scenarios, And Strategic Layout, Xinguang Zhu, Yiming Bao, Zhenong Jin, Xin Li, Sijia Wang, Yueming Wang, Yungui Yang, Cao Xu, Yan Xiong, Bin Han

Bulletin of Chinese Academy of Sciences (Chinese Version)

Life related processes are characterized by high dimensionality and multi-scale properties. Understanding mechanisms underpinning life processes helps promote national healthcare, agricultural development, sustainable ecological civilization, and national security. Current life science research is confronted with an enormous challenge of dimensionality stemming from data explosion and data fragmentation, for which the recent rapid advancement of artificial intelligence (AI) provides novel solutions. AI will catalyze a paradigm shift in life science research from the current experiment based empirical induction to a new closed-loop knowledge acquisition including large scale data collection, model building, model prediction, experimental validation, and iterative of these procedures. Life …

Artificial Intelligence–Driven Paradigm Transformation In Biopharmaceutical R&D: Applications And Emerging Scenarios, Lili Liu, Mingyue Zheng, Ye Yuan, Xutong Li, Rong Fan, Wei Wei, Jinxin Zhao, Guobin Qi, Hua Yue, Likun Gong, Songping Zhang, Jiachen Li, Yuchen Sun, Xiaoyan Chen, Yao Chen, Xin Liu, Xiao Zhang, Yuehong Gao, Jianfeng Li, Kaixian Chen, Guanghui Ma, Jianmin Yue

Bulletin of Chinese Academy of Sciences (Chinese Version)

The biopharmaceutical industry is a critical domain underpinning national scientific and technological innovation development and public health. With the rapid advancement of artificial intelligence (AI) and its deep integration with the life sciences, biomedicine research is undergoing a paradigm shift from traditional experience-driven trial-and-error approaches to data-driven and predictive validation-based models. This study systematically examines the pathways for reshaping research in biomedicine paradigms under the convergence of data-driven, mechanism-driven, and intelligence-driven approaches. It focuses on recent advances in the application of AI across key stages, including drug discovery and design, druggability evaluation, delivery system design and optimization, nonclinical and clinical …

Artificial Intelligence For Cybersecurity: Opportunities, Challenges, And Approaches, Kai Chen, Ding Li, Guozhu Meng, Shouling Ji, Changjiang Li, Yi Yang, Dengguo Feng

Bulletin of Chinese Academy of Sciences (Chinese Version)

Cybersecurity research, institutional structures, and governance policies are undergoing profound transformations. Currently, increasingly covert and rapidly evolving intelligent attacks, coupled with the national urgent expectations for high-level security, are driving significant shifts in the roles and interactions of governments, research institutions, and enterprises. Consequently, this study, based on analyzing the challenges and opportunities of the AI era, explores core application scenarios such as critical information infrastructure protection, national data security, and the maintenance of cyberspace sovereignty. It provides an analysis of artificial intelligence in dimensions such as correlation and causality, and proposes a governance framework, aiming to provide insights for …

Artificial Intelligence For Astronomy: Strategic Opportunities, Policy Challenges And Development Strategies, Jin Chang, Yihan Song, Bing Du, Kefei Wu, Ali Luo, Jifeng Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

To alleviate the bottlenecks hindering the integrated development of artificial intelligence and astronomy in China and to reinforce the country’s strategic edge in science and technology, this study uses systematic analysis and path-comparison approaches to examine the policy requirements for their deep integration. The findings indicate that this topic is closely tied to global competition in science and technology, strategic security, and industrial upgrading. At present, the world has entered a new “astronomy + AI” paradigm, with the United States and the European Union already having taken the lead in establishing corresponding strategic frameworks. Leveraging major scientific infrastructures such as …

Artificial Intelligence Empowering Remote Sensing: Challenges, Paradigms And Strategic Layout, Jiayuan Shen, Peirui Cheng, Zhirui Wang, Wei Liang, Xian Sun, Yirong Wu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Remote sensing science and technology, as a key discipline for Earth observation and global change research, faces systemic challenges in processing massive multi-source data, accurately extracting complex information, and delivering high-timeliness application services. The rapid advances in artificial intelligence (AI) provide a new opportunity to address the deep-seated dilemma in remote sensing of being “data-rich but insufficient in effective information mining”. Guided by a problem-oriented approach, this study first systematically analyzes the core challenges facing the development of remote sensing across four dimensions: data understanding, technical methods, scientific mechanisms, and application ecosystems. It then reviews the technical evolution of AI-empowered …

Artificial Intelligence For Deep Earth Science: Key Challenges, Major Application Scenarios And Development Pathways, Qingyun Di, Liang Zhao, Yikang Zheng, Zhi Geng, Zhichao Yu, Xiaocai Shan, Chao Li, Zhiyao Xu, Pengfei Lv

Bulletin of Chinese Academy of Sciences (Chinese Version)

Deep Earth science is central to understanding Earth’s internal architecture and the coupled evolution of its major spheres, while also underpinning energy security, the supply of critical mineral resources, and resilience to major geohazards. Nevertheless, the advancement of deep Earth science is currently hindered by insufficient in situ observations under extreme conditions, the difficulty of integrating multi-source heterogeneous data, and the limited capability to model complex multiphysics coupling processes. Recent advances in artificial intelligence offer a potential route beyond these limitations. By integrating data-driven learning with physical and geological understanding, AI is reshaping deep Earth science from empirical interpretation to …

Artificial Intelligence For Science: Connotations, Characteristics, And System, Kaihua Chen, Heyang Li, Hongxin Liu, Binbin Zhao, Shuo Yang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Artificial intelligence is profoundly transforming the fundamental nature of scientific research, reshaping its modes of knowledge production and organizational operation, driving the emergence of a new artificial intelligence for science (AI4S) research paradigm, and accelerating full-chain innovation paradigm transformation. This study defines the basic connotations of AI4S across three dimensions, namely, enabling applications, tools and methods, and epistemic knowledge, and systematically identifies five core characteristics: human-machine symbiosis, autonomous evolution, interdisciplinary integration, resource intensity, and open ecosystems. It further constructs a supporting system and operational architecture encompassing layers of infrastructure, data resources, model tools, task execution, and application scenarios. Building on …

Logic And Path Of Transformation Reform Between Old And New Research Evaluation Models, Fang Xu, Xiaoxuan Li

Bulletin of Chinese Academy of Sciences (Chinese Version)

The national 15th Five-Year Plan once again emphasizes breaking the four-only criteria. Why is it so difficult to dismantle the four-only criteria? This study argues that an in-depth analysis of the underlying logical relationship between the old label-based evaluation model and the new connotation-oriented quality evaluation model is required to address this question. The study finds that the label-based evaluation model is a rational choice under specific historical circumstances and it has delivered positive effects. During the transition toward connotation-oriented quality evaluation, problems concerning indicators such as academic papers have been well resolved. Nevertheless, national science and technology awards and …

Upholding Long-Termism In Basic Research To Shape Leading Advantage Of Automotive Industry, Yubo Lian

Bulletin of Chinese Academy of Sciences (Chinese Version)

General Secretary Xi Jinping has pointed out that basic research is the origin of the entire scientific system and the master switch for all technological issues, emphasizing that it must be advanced with greater efforts and more concrete measures. Upholding long-termism in basic research means placing it at the foundation of the innovation chain and maintaining continuous investment with strategic patience characterized by a long-term horizon and high tolerance for failure. Drawing on the author’s industrial practice, this study systematically reviews the characteristics and roles of basic research throughout the development of China’s new energy vehicle industry. In light of …

Advancing Paradigm Of Quantitative Synthetic Biology And Strengthening Mission-Oriented Basic Research, Chenli Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Synthetic biology is an important frontier in the life sciences, yet its further development remains constrained by limited capacity for rational design. Quantitative synthetic biology, which iteratively integrates quantitative modeling with the construction and analysis of synthetic systems, offers a promising paradigm for addressing this challenge. In this perspective, the study discusses the background and motivations underlying the emergence of this field and summarizes recent developments and exploratory efforts. Considering the unique characteristics of quantitative synthetic biology, it is suggested that progress in the field may benefit from strategically organized collaborative research that balances mission-oriented goals with investigator-driven exploration. On …

Viewpoints On Elevating Capability And Appreciation Of Basic Research, Guojie Li, Wei Zhao

Bulletin of Chinese Academy of Sciences (Chinese Version)

The overall capability and appreciation of a country’s basic research are not solely determined by the efforts of individual researchers, but also hinge on the country’s scientific and technological institutional mechanisms and policies. This article presents several viewpoints and suggestions from the perspectives of comprehensively and deeply understanding the connotation of basic research, increasing the proportion of investment in basic research, enhancing the stable support for basic research, and the paradigm shift of AI-driven basic research. These suggestions include: by 2030, adjusting the ratio of pure basic research to oriented basic research from 3.5∶6.5 to 4.5∶5.5, maintaining a balance between …

Problem Formation In Basic Research: Historical Evolution And Contemporary Transformation, Jialing Lyu, Ying Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

“Topic selection” in basic research has long been a central issue in S&T and innovation policy. Traditionally, it has often been understood as the processes of designating promising projects from an existing topic list through peer review and procedural evaluation. Nevertheless, major scientific problems do not always preexist within disciplinary systems, nor are landmark scientific discoveries artificially pre-planned in advance. Rather, they gradually emerge through the continuous interaction among national strategic demands, technological evolution, industrial transformation, and major real-world challenges. This study argues that important directions in basic research are often shaped by the sustained pull of real-world problems on …

Deep Learning Processor: Road To Fundamental Research On Ai Chip, Yunji Chen

Bulletin of Chinese Academy of Sciences (Chinese Version)

Deep learning processor chips serve as an important computation foundation for the artificial intelligence industry, thus has attracted widespread attention from the international communities. The Institute of Computing Technology, Chinese Academy of Sciences took the lead in initiating fundamental research on deep learning processor chips in 2008. At that time, this research direction had not yet entered the mainstream vision of the international communities, with its academic value and development laws yet to gain widespread recognition, and it was confronted with the challenges of three fundamental scientific issues concerning its significance, principle, and architecture.To address the above issues, the research …

Leading Big Science Initiative And Boosting Basic Research, Nianzhi Jiao

Bulletin of Chinese Academy of Sciences (Chinese Version)

As a core model for conducting cutting-edge research through global collaboration, major international science initiative (ISI) has comprehensively reshaped the development scope, resource landscape, research paradigms, talent systems, and governance ecosystems of basic research (BR). ISI and BR are deeply integrated and iteratively coordinated, forming a vital strategy for humanity to tackle major global scientific challenges. Against the backdrop of deep intertwining between scientific and technological competition and global governance, China taking the lead in ISI has become a strategic imperative for the new era, with the UN Ocean Decade Program ocean negative carbon emissions (ONCE) serving as a successful …

On Crucial Role Of The Spirit Of Chinese Scientists In Basic Research, Xin Wang, Chuanxi Wang, Changpu Sun

Bulletin of Chinese Academy of Sciences (Chinese Version)

Basic research is the source of original innovation and the foundation for building a strong nation in science and technology. Compared with applied development research and engineering research, basic research is primarily concerned with exploring the frontiers, proposing new concepts, discovering new laws, and establishing new theories. Its outcomes are often difficult to predict in advance and are rarely subject to sufficient experimental and practical verification within a short time frame. These characteristics expose basic research to three inherent challenges in the philosophy of science. First, the experimental verification of fundamental theories often requires a long period of time. Second, …

Engineering 3d Optical Interconnects And Low-Power Radio Frequency Gaze Tracking, Blake P. Crosby

Theses and Dissertations

This thesis presents two independent research works in optical in- terconnects and radio-frequency (RF)-based gaze tracking. The first work demonstrates a silicon optical waveguide fabricated from four through-silicon vias (TSVs) produced using two-photon-absorption- assisted photo-electrochemical etching. Unlike conventional TSV fabrica- tion methods, this approach enables highly localized, non-line-of-sight etching in silicon using a focused femtosecond laser. Four approximately 5 μm diameter TSVs were etched through a 200 μm silicon wafer in a 7 μm by 7 μm pattern, leaving a central silicon region that functions as a waveguide. The fabricated structure achieved an aspect ratio of approxi- mately 40:1 with …

Effects Of A Peer Mentoring Program For Adolescent Newcomers On Feelings Of Peer Connectedness And School Belonging, Eden Elizabeth Moon Barnhill

Theses and Dissertations

There is a significant lack of empirical evidence regarding the effectiveness of peer mentoring to support newcomer students, particularly for refugee populations. This study evaluated the effects of a peer mentor program for newcomer students on their feelings of peer connectedness and school belonging in a high school setting. Participants were made up of 15 newcomer student mentees across three high schools. Measures were administered pre- and post-intervention, and participants were also interviewed about their experience. Results indicated no quantitative findings of significance but did yield a small positive effect size for peer connectedness. According to qualitative data, many participants …

Hierarchical Parcel Swapping: A Novel Model In Turbulence, Masoomeh Behrang

Theses and Dissertations

Turbulent mixing plays a central role in a wide range of engineering and natural systems, particularly in reactive flows where turbulence--chemistry interactions strongly influence reaction rates, flame structure, and emissions. Accurately modeling these interactions remains a major challenge due to the multiscale and stochastic nature of turbulence, as well as the nonlinear coupling between transport and chemical kinetics. This dissertation develops and evaluates the Hierarchical Parcel Swapping (HiPS) model, a fully stochastic framework designed to represent turbulence-driven transport and scalar mixing without relying on traditional gradient-based closures. HiPS is investigated both as a standalone turbulence model and as a subgrid …

Rheological Protocol To Assess And Optimize Latex Coagulation Dynamics For The Thin Glove Coagulant Dipping Process, Monday U. Okoronkwo, Kok Kong Ng, Wolfram Franke, Gaurav Sant

Chemical and Biochemical Engineering Faculty Research & Creative Works

Many products that directly impact the quality of human life today — gloves, catheters, condoms, and baby bottle teats — are made through the latex-dipping technology. While a variety of methods have been developed – e.g., particle counting, turbidimetry, microscopy, and light scattering – which are suitable for studying the coagulation of latex at very low concentrations, much less work has focused on methods suitable for in-situ characterization of latex coagulation in concentrated solutions (e.g., as relevant to the dipping process). This paper presents a process-relevant rheological protocol for assessing and optimizing latex coagulation dynamics for the thin glove coagulant …

The Use Of Mobile Applications By Non-Governmental Organizations For Volunteer Recruitment And Retention In Egypt, Mona Sami Morshidy

Theses and Dissertations

Abstract 

Non-governmental organizations (NGOs) have increasingly used digital technology and mobile applications to facilitate volunteerism. In Egypt, mobile applications offer significant opportunities to enhance volunteer management. This study explores how mobile applications and digital platforms facilitate volunteering recruitment and retention in Egypt. The study employs a qualitative research design based on 34 semi-structured interviews with NGO representatives and volunteers with varying years of volunteering experience. The findings highlight the mobile application's effects on recruitment, retention, and management, as well as the challenges of adapting it. The results indicate that NGOs primarily use mobile applications to manage existing volunteers, with only …

Air Pollution And Public Health: Global Evidence And Implications, Mohammed Obaid Al-Mansoori

Al-Bahir

Globally, the issue of air pollution keep being one of most serious challenges that affecting environment and human health, coming from emissions of industries, transport, agriculture and also from the fuel people use in homes, in addition to natural events that make the situation worse. This review try to bring together the available evidences about the sources, types, and the health impacts of the main air pollutants, including the gaseous ones like SO₂, O₃, NO₂, and CO, and the particulate matter (PM₁₀, PM₂.₅). Exposure for short or long time to these pollutants is linked with many harmful outcomes, such as …