Artificial Intelligence-Enabled Materials Innovation: Implementation Levels And Strategic Layout, Ziwei Zhao, Fengxiang Zhou, Yanglili Zhou, Can Wang, Pei Zhang, Weihua Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Materials innovation has long been constrained by vast design spaces, complex processing routes, lengthy validation cycles, and difficulties in engineering translation. Traditional research and development models, which mainly rely on accumulated experience, theoretical deduction, and experimental trial and error, have become increasingly insufficient to meet the demand for rapid breakthroughs in critical materials. In recent years, artificial intelligence has been increasingly integrated into materials design, synthesis, and processing, characterization, evaluation, optimization, and application feedback, promoting the transformation of materials innovation from experience-driven exploration to data-driven development and from discrete trial and error to closed-loop optimization. Based on an analysis of …

Artificial Intelligence Empowered Biological Research: Paradigm Shifts, Application Scenarios, And Strategic Layout, Xinguang Zhu, Yiming Bao, Zhenong Jin, Xin Li, Sijia Wang, Yueming Wang, Yungui Yang, Cao Xu, Yan Xiong, Bin Han

Bulletin of Chinese Academy of Sciences (Chinese Version)

Life related processes are characterized by high dimensionality and multi-scale properties. Understanding mechanisms underpinning life processes helps promote national healthcare, agricultural development, sustainable ecological civilization, and national security. Current life science research is confronted with an enormous challenge of dimensionality stemming from data explosion and data fragmentation, for which the recent rapid advancement of artificial intelligence (AI) provides novel solutions. AI will catalyze a paradigm shift in life science research from the current experiment based empirical induction to a new closed-loop knowledge acquisition including large scale data collection, model building, model prediction, experimental validation, and iterative of these procedures. Life …

Artificial Intelligence–Driven Paradigm Transformation In Biopharmaceutical R&D: Applications And Emerging Scenarios, Lili Liu, Mingyue Zheng, Ye Yuan, Xutong Li, Rong Fan, Wei Wei, Jinxin Zhao, Guobin Qi, Hua Yue, Likun Gong, Songping Zhang, Jiachen Li, Yuchen Sun, Xiaoyan Chen, Yao Chen, Xin Liu, Xiao Zhang, Yuehong Gao, Jianfeng Li, Kaixian Chen, Guanghui Ma, Jianmin Yue

Bulletin of Chinese Academy of Sciences (Chinese Version)

The biopharmaceutical industry is a critical domain underpinning national scientific and technological innovation development and public health. With the rapid advancement of artificial intelligence (AI) and its deep integration with the life sciences, biomedicine research is undergoing a paradigm shift from traditional experience-driven trial-and-error approaches to data-driven and predictive validation-based models. This study systematically examines the pathways for reshaping research in biomedicine paradigms under the convergence of data-driven, mechanism-driven, and intelligence-driven approaches. It focuses on recent advances in the application of AI across key stages, including drug discovery and design, druggability evaluation, delivery system design and optimization, nonclinical and clinical …

Artificial Intelligence For Cybersecurity: Opportunities, Challenges, And Approaches, Kai Chen, Ding Li, Guozhu Meng, Shouling Ji, Changjiang Li, Yi Yang, Dengguo Feng

Bulletin of Chinese Academy of Sciences (Chinese Version)

Cybersecurity research, institutional structures, and governance policies are undergoing profound transformations. Currently, increasingly covert and rapidly evolving intelligent attacks, coupled with the national urgent expectations for high-level security, are driving significant shifts in the roles and interactions of governments, research institutions, and enterprises. Consequently, this study, based on analyzing the challenges and opportunities of the AI era, explores core application scenarios such as critical information infrastructure protection, national data security, and the maintenance of cyberspace sovereignty. It provides an analysis of artificial intelligence in dimensions such as correlation and causality, and proposes a governance framework, aiming to provide insights for …

Artificial Intelligence For Astronomy: Strategic Opportunities, Policy Challenges And Development Strategies, Jin Chang, Yihan Song, Bing Du, Kefei Wu, Ali Luo, Jifeng Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

To alleviate the bottlenecks hindering the integrated development of artificial intelligence and astronomy in China and to reinforce the country’s strategic edge in science and technology, this study uses systematic analysis and path-comparison approaches to examine the policy requirements for their deep integration. The findings indicate that this topic is closely tied to global competition in science and technology, strategic security, and industrial upgrading. At present, the world has entered a new “astronomy + AI” paradigm, with the United States and the European Union already having taken the lead in establishing corresponding strategic frameworks. Leveraging major scientific infrastructures such as …

Artificial Intelligence Empowering Remote Sensing: Challenges, Paradigms And Strategic Layout, Jiayuan Shen, Peirui Cheng, Zhirui Wang, Wei Liang, Xian Sun, Yirong Wu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Remote sensing science and technology, as a key discipline for Earth observation and global change research, faces systemic challenges in processing massive multi-source data, accurately extracting complex information, and delivering high-timeliness application services. The rapid advances in artificial intelligence (AI) provide a new opportunity to address the deep-seated dilemma in remote sensing of being “data-rich but insufficient in effective information mining”. Guided by a problem-oriented approach, this study first systematically analyzes the core challenges facing the development of remote sensing across four dimensions: data understanding, technical methods, scientific mechanisms, and application ecosystems. It then reviews the technical evolution of AI-empowered …

Artificial Intelligence For Deep Earth Science: Key Challenges, Major Application Scenarios And Development Pathways, Qingyun Di, Liang Zhao, Yikang Zheng, Zhi Geng, Zhichao Yu, Xiaocai Shan, Chao Li, Zhiyao Xu, Pengfei Lv

Bulletin of Chinese Academy of Sciences (Chinese Version)

Deep Earth science is central to understanding Earth’s internal architecture and the coupled evolution of its major spheres, while also underpinning energy security, the supply of critical mineral resources, and resilience to major geohazards. Nevertheless, the advancement of deep Earth science is currently hindered by insufficient in situ observations under extreme conditions, the difficulty of integrating multi-source heterogeneous data, and the limited capability to model complex multiphysics coupling processes. Recent advances in artificial intelligence offer a potential route beyond these limitations. By integrating data-driven learning with physical and geological understanding, AI is reshaping deep Earth science from empirical interpretation to …

Artificial Intelligence For Science: Connotations, Characteristics, And System, Kaihua Chen, Heyang Li, Hongxin Liu, Binbin Zhao, Shuo Yang

Bulletin of Chinese Academy of Sciences (Chinese Version)

Artificial intelligence is profoundly transforming the fundamental nature of scientific research, reshaping its modes of knowledge production and organizational operation, driving the emergence of a new artificial intelligence for science (AI4S) research paradigm, and accelerating full-chain innovation paradigm transformation. This study defines the basic connotations of AI4S across three dimensions, namely, enabling applications, tools and methods, and epistemic knowledge, and systematically identifies five core characteristics: human-machine symbiosis, autonomous evolution, interdisciplinary integration, resource intensity, and open ecosystems. It further constructs a supporting system and operational architecture encompassing layers of infrastructure, data resources, model tools, task execution, and application scenarios. Building on …

Logic And Path Of Transformation Reform Between Old And New Research Evaluation Models, Fang Xu, Xiaoxuan Li

Bulletin of Chinese Academy of Sciences (Chinese Version)

The national 15th Five-Year Plan once again emphasizes breaking the four-only criteria. Why is it so difficult to dismantle the four-only criteria? This study argues that an in-depth analysis of the underlying logical relationship between the old label-based evaluation model and the new connotation-oriented quality evaluation model is required to address this question. The study finds that the label-based evaluation model is a rational choice under specific historical circumstances and it has delivered positive effects. During the transition toward connotation-oriented quality evaluation, problems concerning indicators such as academic papers have been well resolved. Nevertheless, national science and technology awards and …

Upholding Long-Termism In Basic Research To Shape Leading Advantage Of Automotive Industry, Yubo Lian

Bulletin of Chinese Academy of Sciences (Chinese Version)

General Secretary Xi Jinping has pointed out that basic research is the origin of the entire scientific system and the master switch for all technological issues, emphasizing that it must be advanced with greater efforts and more concrete measures. Upholding long-termism in basic research means placing it at the foundation of the innovation chain and maintaining continuous investment with strategic patience characterized by a long-term horizon and high tolerance for failure. Drawing on the author’s industrial practice, this study systematically reviews the characteristics and roles of basic research throughout the development of China’s new energy vehicle industry. In light of …

Advancing Paradigm Of Quantitative Synthetic Biology And Strengthening Mission-Oriented Basic Research, Chenli Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

Synthetic biology is an important frontier in the life sciences, yet its further development remains constrained by limited capacity for rational design. Quantitative synthetic biology, which iteratively integrates quantitative modeling with the construction and analysis of synthetic systems, offers a promising paradigm for addressing this challenge. In this perspective, the study discusses the background and motivations underlying the emergence of this field and summarizes recent developments and exploratory efforts. Considering the unique characteristics of quantitative synthetic biology, it is suggested that progress in the field may benefit from strategically organized collaborative research that balances mission-oriented goals with investigator-driven exploration. On …

Viewpoints On Elevating Capability And Appreciation Of Basic Research, Guojie Li, Wei Zhao

Bulletin of Chinese Academy of Sciences (Chinese Version)

The overall capability and appreciation of a country’s basic research are not solely determined by the efforts of individual researchers, but also hinge on the country’s scientific and technological institutional mechanisms and policies. This article presents several viewpoints and suggestions from the perspectives of comprehensively and deeply understanding the connotation of basic research, increasing the proportion of investment in basic research, enhancing the stable support for basic research, and the paradigm shift of AI-driven basic research. These suggestions include: by 2030, adjusting the ratio of pure basic research to oriented basic research from 3.5∶6.5 to 4.5∶5.5, maintaining a balance between …

Problem Formation In Basic Research: Historical Evolution And Contemporary Transformation, Jialing Lyu, Ying Wang

Bulletin of Chinese Academy of Sciences (Chinese Version)

“Topic selection” in basic research has long been a central issue in S&T and innovation policy. Traditionally, it has often been understood as the processes of designating promising projects from an existing topic list through peer review and procedural evaluation. Nevertheless, major scientific problems do not always preexist within disciplinary systems, nor are landmark scientific discoveries artificially pre-planned in advance. Rather, they gradually emerge through the continuous interaction among national strategic demands, technological evolution, industrial transformation, and major real-world challenges. This study argues that important directions in basic research are often shaped by the sustained pull of real-world problems on …

Deep Learning Processor: Road To Fundamental Research On Ai Chip, Yunji Chen

Bulletin of Chinese Academy of Sciences (Chinese Version)

Deep learning processor chips serve as an important computation foundation for the artificial intelligence industry, thus has attracted widespread attention from the international communities. The Institute of Computing Technology, Chinese Academy of Sciences took the lead in initiating fundamental research on deep learning processor chips in 2008. At that time, this research direction had not yet entered the mainstream vision of the international communities, with its academic value and development laws yet to gain widespread recognition, and it was confronted with the challenges of three fundamental scientific issues concerning its significance, principle, and architecture.To address the above issues, the research …

Leading Big Science Initiative And Boosting Basic Research, Nianzhi Jiao

Bulletin of Chinese Academy of Sciences (Chinese Version)

As a core model for conducting cutting-edge research through global collaboration, major international science initiative (ISI) has comprehensively reshaped the development scope, resource landscape, research paradigms, talent systems, and governance ecosystems of basic research (BR). ISI and BR are deeply integrated and iteratively coordinated, forming a vital strategy for humanity to tackle major global scientific challenges. Against the backdrop of deep intertwining between scientific and technological competition and global governance, China taking the lead in ISI has become a strategic imperative for the new era, with the UN Ocean Decade Program ocean negative carbon emissions (ONCE) serving as a successful …

On Crucial Role Of The Spirit Of Chinese Scientists In Basic Research, Xin Wang, Chuanxi Wang, Changpu Sun

Bulletin of Chinese Academy of Sciences (Chinese Version)

Basic research is the source of original innovation and the foundation for building a strong nation in science and technology. Compared with applied development research and engineering research, basic research is primarily concerned with exploring the frontiers, proposing new concepts, discovering new laws, and establishing new theories. Its outcomes are often difficult to predict in advance and are rarely subject to sufficient experimental and practical verification within a short time frame. These characteristics expose basic research to three inherent challenges in the philosophy of science. First, the experimental verification of fundamental theories often requires a long period of time. Second, …

Engineering 3d Optical Interconnects And Low-Power Radio Frequency Gaze Tracking, Blake P. Crosby

Theses and Dissertations

This thesis presents two independent research works in optical in- terconnects and radio-frequency (RF)-based gaze tracking. The first work demonstrates a silicon optical waveguide fabricated from four through-silicon vias (TSVs) produced using two-photon-absorption- assisted photo-electrochemical etching. Unlike conventional TSV fabrica- tion methods, this approach enables highly localized, non-line-of-sight etching in silicon using a focused femtosecond laser. Four approximately 5 μm diameter TSVs were etched through a 200 μm silicon wafer in a 7 μm by 7 μm pattern, leaving a central silicon region that functions as a waveguide. The fabricated structure achieved an aspect ratio of approxi- mately 40:1 with …

Effects Of A Peer Mentoring Program For Adolescent Newcomers On Feelings Of Peer Connectedness And School Belonging, Eden Elizabeth Moon Barnhill

Theses and Dissertations

There is a significant lack of empirical evidence regarding the effectiveness of peer mentoring to support newcomer students, particularly for refugee populations. This study evaluated the effects of a peer mentor program for newcomer students on their feelings of peer connectedness and school belonging in a high school setting. Participants were made up of 15 newcomer student mentees across three high schools. Measures were administered pre- and post-intervention, and participants were also interviewed about their experience. Results indicated no quantitative findings of significance but did yield a small positive effect size for peer connectedness. According to qualitative data, many participants …

Hierarchical Parcel Swapping: A Novel Model In Turbulence, Masoomeh Behrang

Theses and Dissertations

Turbulent mixing plays a central role in a wide range of engineering and natural systems, particularly in reactive flows where turbulence--chemistry interactions strongly influence reaction rates, flame structure, and emissions. Accurately modeling these interactions remains a major challenge due to the multiscale and stochastic nature of turbulence, as well as the nonlinear coupling between transport and chemical kinetics. This dissertation develops and evaluates the Hierarchical Parcel Swapping (HiPS) model, a fully stochastic framework designed to represent turbulence-driven transport and scalar mixing without relying on traditional gradient-based closures. HiPS is investigated both as a standalone turbulence model and as a subgrid …

Rheological Protocol To Assess And Optimize Latex Coagulation Dynamics For The Thin Glove Coagulant Dipping Process, Monday U. Okoronkwo, Kok Kong Ng, Wolfram Franke, Gaurav Sant

Chemical and Biochemical Engineering Faculty Research & Creative Works

Many products that directly impact the quality of human life today — gloves, catheters, condoms, and baby bottle teats — are made through the latex-dipping technology. While a variety of methods have been developed – e.g., particle counting, turbidimetry, microscopy, and light scattering – which are suitable for studying the coagulation of latex at very low concentrations, much less work has focused on methods suitable for in-situ characterization of latex coagulation in concentrated solutions (e.g., as relevant to the dipping process). This paper presents a process-relevant rheological protocol for assessing and optimizing latex coagulation dynamics for the thin glove coagulant …

The Use Of Mobile Applications By Non-Governmental Organizations For Volunteer Recruitment And Retention In Egypt, Mona Sami Morshidy

Theses and Dissertations

Abstract 

Non-governmental organizations (NGOs) have increasingly used digital technology and mobile applications to facilitate volunteerism. In Egypt, mobile applications offer significant opportunities to enhance volunteer management. This study explores how mobile applications and digital platforms facilitate volunteering recruitment and retention in Egypt. The study employs a qualitative research design based on 34 semi-structured interviews with NGO representatives and volunteers with varying years of volunteering experience. The findings highlight the mobile application's effects on recruitment, retention, and management, as well as the challenges of adapting it. The results indicate that NGOs primarily use mobile applications to manage existing volunteers, with only …

Air Pollution And Public Health: Global Evidence And Implications, Mohammed Obaid Al-Mansoori

Al-Bahir

Globally, the issue of air pollution keep being one of most serious challenges that affecting environment and human health, coming from emissions of industries, transport, agriculture and also from the fuel people use in homes, in addition to natural events that make the situation worse. This review try to bring together the available evidences about the sources, types, and the health impacts of the main air pollutants, including the gaseous ones like SO₂, O₃, NO₂, and CO, and the particulate matter (PM₁₀, PM₂.₅). Exposure for short or long time to these pollutants is linked with many harmful outcomes, such as …

Investigations On The Effect Of Nano Titanium Oxide On The Properties Of Nickel Alloy Using Powder Metallurgy Technique, Sawsan F. Ahmed, Muaamar A .Kamil

Al-Bahir

Powder metallurgy method was used to prepare nickel-based samples enriched with nano-chromium at a fixed ratio of 5 %wt. Different percentages of nano-titanium oxide were added at (0, 5, 10, 15, 20) %wt. . A 10 mm diameter die was used and the pressing process was carried out with a hydraulic press in one direction at a pressure of 10 tons. The resulting alloys were sintered at 1000°C for two hours. Several tests were performed, including X-ray diffraction of the primary and post-mixed powders, which showed that the nickel was in the FCC (Cubic) system and completely pure, the nano-chromium …

Engineering And Geochemical Assessment Of Grey Clay From Iko Town, South-South Nigeria, For Building Construction Applications, Ubong Williams Robert, Sunday Edet Etuk, Okechukwu Ebuka Agbasi, Grace Peter Umoren

Al-Bahir

Grey clay is abundantly available in Iko Town in South-South Nigeria. However, there is no scientific information on its potentialities. Hence, this research has been designed to determine its suitability for building purpose, considering how necessary shelter is for the survival of man. The flowability, gradation, and geochemistry of the clay were assessed. Also, samples were prepared from the clay under same conditions, dried sufficiently, and then subjected to various tests to examine their heat transfer and strength behaviors. For each test category, ten samples were prepared and used and the data obtained were averaged per test. It was found …

Physical Modeling By Froude Number Similarity Law: Experimental Apparatus For Tests With Offshore Structure Anchors Penetrated With Water Jet, Alana Stern Retzlaff, Adriana Thais Mendes Kich, Caroline Peter, Karina Retzlaff Camargo, Diego De Freitas Fagundes

Seatific Journal

The torpedo pile is a Brazilian technology widely employed for anchoring offshore structures. Studies indicate that the use of vertical water jets applied at the pile tip can increase penetration efficiency and reduce inclination during installation. Considering the high costs and logistical challenges of full-scale testing, investigations using reduced physical models become a viable alternative. This study presents the development and application of an experimental apparatus based on the Froude Number Similarity Law, designed to perform penetration and pullout tests on reduced-scale torpedo pile models without fins, at a 1:76 length scale. To validate the system, an initial series of …

Analysis On Thermo-Viscous Steady Fluid Motion Over An Impermeable Infinitely Stretched Horizontal Moving Rectangular Surface, P. Krishna, N. Pothanna, K. Spandana

Mansoura Engineering Journal

This study presents analysis on thermo-viscous steady fluid motion over an impermeable infinitely stretched horizontal moving rectangular surface. The numerical results have been found employing R-K method of order 6 shooting techniques developed in Mathematica software ND solve for the flow adaptable equations comprising temperature and velocity. The flow behavior and the impacts of material constraints on the flow region have been analyzed and deliberated taking the help from the generated graphs. The variations of these flow fields have been studied for wide spectrum of physical characteristics which influences the nature of thermo-viscous fluid. The impact of viscosity, constant pressure …

Factors Influencing Tourist Interest In Walking Tours In The Kota Tua Area, Novi Handayani, Adrian Hartanto

Journal of Indonesian Tourism and Policy Studies

This study aims to analyze the extent to which the variables of Attraction, Accessibility, Cost and Tarif, Facilities, and Information contribute to Walking tour Interest, both individually (partially) and collectively (simultaneously).  As previous research states that Indonesia has one of the lowest levels of mobility. The average Indonesian walks only 3513 steps per day, while the recommended daily step count for maintaining good health is 5000. This study uses Multiple Linear Regression Analysis as its analysis method using partial hypothesis testing (t-test) and simultaneous hypothesis testing (f-test).. Data were collected through an online questionnaire distributed via Google Form to …

A Conceptual Model Of The External Costs Of Truck Overloading On Road Damage, Emissions, And Traffic Congestion: A Systematic Literature Review, Aleksius Sitepu, Sutanto Soehodho, Andyka Kusuma

Smart City

Freight transport services cannot be separated from the infrastructure and facilities involved, each of which faces its own challenges in delivering optimal performance in the logistics sector. A common challenge in Indonesia’s road sector is the presence of overloaded freight vehicles, which has become a national issue. This phenomenon has a negative impact not only on road infrastructure but also on the environment and traffic. This study aims to develop a conceptual model of the external costs caused by truck overloading practices in terms of road infrastructure damage, increased exhaust emissions, and traffic congestion through a systematic literature review. This …

Leveraging A Centralized Fleet Assignment Management For An Aviation Resilience, Inof Seno Acton Mr., Sutanto Soehodho, Nahry Yusuf

Smart City

Since deregulation in the aviation industry, competition among airlines has intensified. This competition is shown by the increasing number of routes, service times, aircraft, and airports served. This competition causes not all flight services to meet their targets, resulting in aircraft operating less efficiently. Passenger seats are not filled, and flight delays are becoming more frequent. Obviously, this will negatively impact consumers and the airline's finances. The study focused on assigning the fleet used to serve flights to maintain existing aviation services and improve aircraft operational efficiency. This study aims to maximize profits by optimizing fleet assignments through the Centralized …

Decarbonizing Electrical Substations: An Integrative Review Of Green Technologies And Sustainable Practices Across The Infrastructure Life Cycle, Sulthan Syah Ali, Mohammed Ali Berawi, Mustika Sari

Smart City

Decarbonization of electrical infrastructure s becoming increasingly important in efforts to meet climate change mitigation targets, particularly in reducing emissions from substations. However, conventional substations continue to release significant quantities of GHG emissions throughout their life cycle As an example, a typical 500 kV substation emits around 150,000 tCO2e from construction to decommissioning. In addition, the development of green substation concepts remains limited, particularly in Indonesia where standardized approaches are not yet established. In response to the need for more sustainable power infrastructure, this study aims to identify, classify, and review all types of green technologies, practices, and innovations that …