Digital Commons Network^™

Evaluations Of Digital Public Health Interventions In The Who Southeast Asia Region: A Systematic Literature Review, Nachiket Gudi, Elstin Anbu Raj, Beate Jahn, Uwe Siebert

Open Access archive

Introduction Digital health technologies have been enhancing the capacity of healthcare providers and, thereby, the delivery of targeted health services. The Southeast Asia Region (SEAR) has invested in strengthening digital public health. Many digital health interventions have been implemented in public health settings but are rarely assessed using the holistic health technology assessment (HTA) approach. Methods A systematic literature review was performed to provide an overview of evaluations of digital public health interventions in the World Health Organization (WHO) SEAR. Searches were conducted on four electronic databases. Screening title abstracts and full texts was independently conducted by two reviewers, followed …

Pyrophosphate-Free Glycolysis In Clostridium Thermocellum Increases Both Thermodynamic Driving Force And Ethanol Titers, Bishal Dev Sharma, Shuen Hon, Eashant Thusoo, David M. Stevenson, Daniel Amador-Noguez, Adam M. Guss, Lee R. Lynd, Daniel G. Olson

Dartmouth Scholarship

Background

Clostridium thermocellum is a promising candidate for production of cellulosic biofuels, however, its final product titer is too low for commercial application, and this may be due to thermodynamic limitations in glycolysis. Previous studies in this organism have revealed a metabolic bottleneck at the phosphofructokinase (PFK) reaction in glycolysis. In the wild-type organism, this reaction uses pyrophosphate (PPi) as an energy cofactor, which is thermodynamically less favorable compared to reactions that use ATP as a cofactor. Previously we showed that replacing the PPi-linked PFK reaction with an ATP-linked reaction increased the thermodynamic driving force of glycolysis, but only had …

Grain Boundary Solute Segregation Across The 5d Space Of Crystallographic Character, Lydia Harris Serafin

Theses and Dissertations

Solute segregation in materials with grain boundaries (GBs) has emerged as a popular method to thermodynamically stabilize nanocrystalline structures. However, the impact of varied GB crystallographic character on solute segregation has never been thoroughly examined. This work examines Co solute segregation in a dataset of 7272 Al bicrystal GBs that span the 5D space of GB crystallographic character. Considerable attention is paid to verification of the calculations in the diverse and large set of GBs. In addition, the results of this work are favorably validated against similar bicrystal and polycrystal simulations. As with other work, we show that Co atoms …

Beyond The Surface: Understanding Temperature Polarisation In Dcmd Membranes Through Varied Operational Parameters, Hiras Ahamed Hijaz, Masoumeh Zargar, Abdellah Shafieian, Amir Razmjou, Mehdi Khiadani

Research outputs 2022 to 2026

Conventionally, a single Temperature Polarisation Coefficient (TPC) value is calculated to quantify Temperature Polarisation (TP). In this research, the extent of polarisation is investigated by capturing temperature profiles at specific points along a MD membrane using miniature thermocouples, eliminating the need for TPC calculations. The extent of polarisation at a point is affected by two contributory factors, namely the proximity of flow inlets and the difference in vapour pressure across the membrane at that point. Under this direction, this work examined the influence of permeate temperature, feed salinity, and flow direction on the development of the temperature profiles. Our analysis …

Recent Trends And Biases In Mesophotic Ecosystem Research, Veronica Z. Radice, Alejandra Hernández-Agreda, Gonzalo Pérez-Rosales, Ryan Booker, Jessica Bellworthy, Manon Broadribb, Gaby E. Carpenter, Clara Diaz, Ryan J. Eckert, Nicola L. Foster, Johanna C. Gijsbers, Erika Gress, Jack H. Laverick, Valerio Micaroni, Miriam Pierotti, Héloïse Rouzé, Angela Stevenson, Alexis B. Sturm, Pim Bongaerts

School of Biological and Marine Sciences

Mesophotic ecosystems (approx. 30-150 m) represent a significant proportion of the world's oceans yet have long remained understudied due to challenges in accessing these deeper depths. Owing to advances in underwater technologies and a growing scientific and management interest, there has been a major expansion in research of both (sub)tropical mesophotic coral ecosystems and temperate mesophotic ecosystems. Here, we characterize the recent global trends in mesophotic research through an updated release of the 'mesophotic.org' database (www.mesophotic.org) where we reviewed and catalogued 1500 scientific publications. In doing so, we shed light on four major research biases: a gross imbalance in (a) …

Terrestrial Evidence For Volcanogenic Sulfate-Driven Cooling Event ~30 Ka Before The Cretaceous–Paleogene Mass Extinction: Volcanism-Induced Cooling ~30 Ka Pre-K–Pg Boundary, Lauren O'Connor, Rhodri Jerrett, Gregory Price, Tyler Lyson, Sabine Lengger, Francien Peterse, Bart Van Dongen

School of Geography, Earth and Environmental Sciences

Alongside the Chicxulub meteorite impact, Deccan volcanism is considered a primary trigger for the Cretaceous–Paleogene (K–Pg) mass extinction. Models suggest that volcanic outgassing of carbon and sulfur—potent environmental stressors—drove global temperature change, but the relative timing, duration, and magnitude of such change remains uncertain. Here, we use the organic paleothermometer MBT′5me and the carbon-isotope composition of two K–Pg-spanning lignites from the western Unites States, to test models of volcanogenic air temperature change in the ~100 kyr before the mass extinction. Our records show long-term warming of ~3°C, probably driven by Deccan CO2 emissions, and reveal a transient (<10 kyr) ~5°C cooling event, coinciding with the peak of the Poladpur “pulse” of Deccan eruption ~30 kyr before the K–Pg boundary. This cooling was likely caused by the aerosolization of volcanogenic sulfur. Temperatures returned to pre-event values before the mass extinction, suggesting that, from the terrestrial perspective, volcanogenic climate change was not the primary cause of K–Pg extinction.

Development Of New Controller And Associated Cybersecurity Issues With Battery Energy Storage Integrated With Microgrid, Syeda Afra Saiara

Electronic Theses and Dissertations Archive

Battery energy storage system (BESS) plays a crucial role in integrating renewable sources in microgrids. However, robust BESS controllers are needed to carry out this function properly. Existing controllers suffer from overshoots and slow convergence issues. This thesis proposes a novel Sigma Delta Modulation (SDM) controller for BESS in solar photovoltaic (PV) connected microgrids to address the limitations of existing controllers. The performance of SDM has been compared with that of the Proportional Integral (PI) and Fuzzy Logic based controllers. Also, the thesis addresses the cybersecurity issues in solar PV based microgrids. The Ensemble Learning technique and an Improved Ensemble …

Amorfe: An Ai-Integrated Interactive Brainstorming Interface, Ipshita Pal

Theses

Amorfe is an interactive multi-touch digital interface that reimagines brainstorming and collaboration using artificial intelligence (AI). Designed to make ideation more dynamic, the platform allows participants to explore, merge, and refine ideas in real time. AI is a creative catalyst, offering unpredictable outcomes and streamlining the brainstorming process. This makes Amorfe engaging, intuitive, and inclusive, encouraging active participation. The platform’s potential was demonstrated through a hypothetical scenario: “How do we create more green spaces on the RIT campus?” Four participants explored various brainstorming phases through touch interaction, leading to the creation of a prototype simulation video and a promotional video. …

Rental Property Demand And Supply Analysis Using Machine Learning, Ahmed Amiri

Theses

The real estate market in Dubai is famous for its activity and stimulating potential due to the geographical position of the emirate, well-developed transport and legal framework. Timely determination and prediction of rental price is crucial for investors, property owners and managers, tenants and authorities in their decision making to maximize returns and ensure market stability. Traditional approaches are insufficient for the analysis of the temporal and spatial relations between property characteristics and market processes, which require the use of sophisticated machine learning algorithms. This paper aims to predict the rental prices of properties in Dubai using machine learning models …

Social Media Intelligence: Responding To Crime And Violence In The Digital World, Chloe Lynn Sitton

Theses

The integration of social media into everyday life has transformed how crime is committed, communicated, and investigated. This capstone project examines the emerging field of social media intelligence and its growing influence on modern policing, surveillance, and the community. Drawing from sociological theory, law enforcement practice, legal analysis, and community-based research, this project offers a far-reaching interdisciplinary view of how social media is shaping crime and justice in the United States.

Schedulability Analysis Of Multi-Phase Limited-Preemption Tasks, Benjamin Standaert

McKelvey School of Engineering Graduate Student Theses & Dissertations

This work addresses hard real-time systems, in which tasks must be scheduled so that they are guaranteed to meet deadlines. In particular, when tasks execute across multiple domains with high preemption costs, the combined cost of these preemptions can cause the system to become unschedulable. The number of preemptions must therefore be bounded to limit the overall task execution time, while ensuring that task blocking times are small enough to allow the system to be schedulable. Prior work introduces the Multi-Phase Secure model, which describes a more exact version of this scenario, and an algorithm to determine schedulability of sporadic …

Codifying Domesticity: The Story Of The Recommended Minimum Requirements For Small Dwelling Construction Of 1923, The Housing Policy Of The Hoover Secretariat, And The Impact On American Residential Architecture, Noah Morris

Graduate School of Architecture & Urban Design Theses & Dissertations

During the nineteenth and twentieth centuries, fire disasters and health-safety issues led to the widespread adoption of building codes. While the National Board of Fire Underwriters published the National Building Code in 1905, the code did not maintain regulatory consistency across the nation. This lack of consistency across the nation and socio-economic factors contributed to a nation-wide housing shortage of a million units by 1919. During World War I, the government addressed the housing crisis through the United States Housing Corporation and Emergency Fleet Corporation, building public housing based on the ideals of the Garden City Movement.[1] Following the …

A Computational And Mathematical Approach To The Preclinical Development Of Alpha Emitting Radiopharmaceutical Therapies, Abdulaziz Said

McKelvey School of Engineering Graduate Student Theses & Dissertations

Numerous candidate nuclides have been undergoing rigorous preclinical development in the pursuit of novel targeted therapies. Successful development of these drugs relies on the understanding of physiological impacts at the macro and micro scales, in addition to a scalable process for their production. Here, mathematical and computerized approaches have been developed to guide this preclinical development. In this report, two alpha emitting nuclides Pb-212 and Ra-223 are modeled. Radium-223 dichloride citrate a newly approved ion indicated for treatment of bone metastatic castrate resistant prostate cancer, irradiates lesions through targeted uptake in bone at sites of disease. We have undertaken the …

Safety And Optimality Monitors For Learning-Enabled Systems Using Conformal Prediction, Jackson Cox

McKelvey School of Engineering Graduate Student Theses & Dissertations

The use of machine learning to create data-driven plant models and controllers has led to an increased need for safety and optimality monitors for model-based systems. System plant models are subject to uncertainty due to learning constraints such as unseen data and overfitting or physical constraints such as unknown dynamics and noise. This uncertainty is detrimental to safety-critical systems and must be properly regulated. To curb this uncertainty, we create prediction sets using the guarantees provided by Conformal Prediction. With a user-specified high probability, these prediction sets contain the true plant system states for an entire prediction horizon, which we …

Capacity-Weighted Figures-Of-Merit For Battery Transport Metrics, Cj Sturgill, Christopher Sutton, Julian Schwenzel, Morgan Stefik

Faculty Publications

New battery materials with improved transport are needed. Typical measurements yield widely varying voltage-dependent diffusivities and reporting practices are diverse. Some materials (e.g. first-order phase change) have most redox occur at a specific voltage and may be sufficiently represented by singular transport metrics. Many rapid intercalation materials, however, exhibit second-order phase transitions with redox over a broad voltage range. How should such cases be compared? The use of capacity-weighted average values is suggested where voltage-dependent metrics are consolidated into representative descriptors as figures-of-merit. Examples are elaborated where differential capacity (dQ/dV) is used to derive a …

Examining The Internet Hunting Styles Of Violent Sexual Predators Who Rape And Murder Their Victims, Rebecca Meyers

Walden Dissertations and Doctoral Studies

The proposed study sought to explore the impact of the internet on the hunting styles of sexual predators who sexually assault and kill their victims. A sample of 32 cases, divided equally among offenders who used the internet to target adult females and those who did not use the internet, was used for the study. The findings showed that various internet-based platforms were used for targeting, including dating apps such as Grindr, Match.com, Meetme.com, Tinder, Craigslist, Sex chat rooms, Kik Messenger, and BDSM sites. Three themes emerged about the impact of the internet on the hunting styles of sexual predators …

Suicide Risk Assessment And Student Competency In Cacrep-Accredited Master's Counseling Programs, Meghan Kyle O'Meara

Walden Dissertations and Doctoral Studies

Suicide remains a public health issue, demanding proficient training of future counselors in suicide risk assessment (SRA). However, concerns persist regarding the competency of counselors-in-training (CITs) in this crucial area. This study explored the predictive relationship between theory of planned behavior (TPB) constructs and students’ perceived competency in SRA. Grounded in the TPB, the research addressed how attitudes (ATT), subjective norms (SN), and perceived behavioral control (PBC) influence intentions and subsequent behavior, using a nonexperimental survey design to collect data from students in Council for Accreditation of Counseling & Related Educational Programs (CACREP)–accredited master's counseling programs via a comprehensive questionnaire. …

Strategies Small Business Leaders Use To Retain Employees To Reduce Turnover Costs, Karla Gilchrist-Saunders

Walden Dissertations and Doctoral Studies

Failure to retain employees negatively affects organizational financial sustainability. Small business leaders become concerned when their organizations fail to retain employees, resulting in increased costs and decreased competitiveness, organizational knowledge, team dynamics, and valuable human resources. Grounded in transformational leadership theory, the purpose of this qualitative pragmatic inquiry study was to identify and explore leadership strategies some small business leaders use to retain employees to reduce turnover costs. The participants were six small business leaders in the Washington, DC, metropolitan area with successful strategies used to retain employees to reduce turnover costs. Data were collected from semistructured interviews and publicly …

The Psychological And Physical Impact Of The Opioid Crisis On Families, Adrienne Antoinette Hunter Wells Green

Walden Dissertations and Doctoral Studies

Many rural areas in the United States have experienced an opioid crisis. Social support programs could be created to address social support for the families affected by opioid addiction. The purpose of this non-experimental, cross-sectional research study was to examine the possible relationship between (a) prescription or non-prescription addiction; (b) opioid addiction or another addiction; (c) the amount of family social support of a family member who has ongoing interactions with the individual struggling with addiction; and (d) stress of the family member in a rural area. Bowen’s family systems theory provided the theoretical framework for the study. A non-probability …

Gene Expression Regulation By Au-Rich Elements And Au-Rich Element Binding Proteins, Courtney Fay Jungers

Arts & Sciences Graduate Student Theses and Dissertations

The regulation of messenger RNA (mRNA) splicing, stability, and translation efficiency are major modes for controlling gene expression – which is essential for life. RNA-binding proteins (RBPs) and microRNAs (miRNAs) are trans-acting factors that bind to cis-elements influencing the stability and translation of the mRNA transcript. AU-rich elements (AREs) are cis-elements that are targeted by AU-rich element binding proteins (ARE-BPs). Here, I show a novel role for AREs and AU-rich element binding protein 1 (AUF1) during alternative splicing and report on interactions of RBPs and miRNAs to design a new treatment for breast cancer by interrupting these interactions in the …

Enhanced Lsmc For Valuation Of Options, Amr Mekawy

Theses and Dissertations

In the world of finance, whether you are a hedger or a speculator, a risk-adverse or a risk-advocate, the use of financial instruments and derivatives will remain pertinent to providing new opportunities for mitigating risks as well as generating profit. Among these instruments are Options, which regardless of their complexity, can be an extremely versatile tool to be utilized across a wide range of different markets.

An option is a derivative that gives the holder the right, but not the obligation to buy or sell the underlying asset either before or at the maturity date of the contract. There are …

Targeting Corticotropin-Releasing Hormone Receptor Type 1 (Crhr1) Neurons: Validating The Specificity Of A Novel Transgenic Crhr1-Flpo Mouse

Faculty, Staff and Student Publications

Corticotropin-releasing hormone (CRH) signaling through its cognate receptors, CRHR1 and CRHR2, contributes to diverse stress-related functions in the mammalian brain. Whereas CRHR2 is predominantly expressed in choroid plexus and blood vessels, CRHR1 is abundantly expressed in neurons in discrete brain regions, including the neocortex, hippocampus and nucleus accumbens. Activation of CRHR1 influences motivated behaviors, emotional states, and learning and memory. However, it is unknown whether alterations in CRHR1 signaling contribute to aberrant motivated behaviors observed, for example, in stressful contexts. These questions require tools to manipulate CRHR1 selectively. Here we describe and validate a novel Crhr1-FlpO mouse. Using bacterial artificial …

Examining The Internet Hunting Styles Of Violent Sexual Predators Who Rape And Murder Their Victims, Rebecca Meyers

Walden Dissertations and Doctoral Studies

The proposed study sought to explore the impact of the internet on the hunting styles of sexual predators who sexually assault and kill their victims. A sample of 32 cases, divided equally among offenders who used the internet to target adult females and those who did not use the internet, was used for the study. The findings showed that various internet-based platforms were used for targeting, including dating apps such as Grindr, Match.com, Meetme.com, Tinder, Craigslist, Sex chat rooms, Kik Messenger, and BDSM sites. Three themes emerged about the impact of the internet on the hunting styles of sexual predators …

Suicide Risk Assessment And Student Competency In Cacrep-Accredited Master's Counseling Programs, Meghan Kyle O'Meara

Walden Dissertations and Doctoral Studies

Suicide remains a public health issue, demanding proficient training of future counselors in suicide risk assessment (SRA). However, concerns persist regarding the competency of counselors-in-training (CITs) in this crucial area. This study explored the predictive relationship between theory of planned behavior (TPB) constructs and students’ perceived competency in SRA. Grounded in the TPB, the research addressed how attitudes (ATT), subjective norms (SN), and perceived behavioral control (PBC) influence intentions and subsequent behavior, using a nonexperimental survey design to collect data from students in Council for Accreditation of Counseling & Related Educational Programs (CACREP)–accredited master's counseling programs via a comprehensive questionnaire. …

Strategies Small Business Leaders Use To Retain Employees To Reduce Turnover Costs, Karla Gilchrist-Saunders

Walden Dissertations and Doctoral Studies

Failure to retain employees negatively affects organizational financial sustainability. Small business leaders become concerned when their organizations fail to retain employees, resulting in increased costs and decreased competitiveness, organizational knowledge, team dynamics, and valuable human resources. Grounded in transformational leadership theory, the purpose of this qualitative pragmatic inquiry study was to identify and explore leadership strategies some small business leaders use to retain employees to reduce turnover costs. The participants were six small business leaders in the Washington, DC, metropolitan area with successful strategies used to retain employees to reduce turnover costs. Data were collected from semistructured interviews and publicly …

The Psychological And Physical Impact Of The Opioid Crisis On Families, Adrienne Antoinette Hunter Wells Green

Walden Dissertations and Doctoral Studies

Many rural areas in the United States have experienced an opioid crisis. Social support programs could be created to address social support for the families affected by opioid addiction. The purpose of this non-experimental, cross-sectional research study was to examine the possible relationship between (a) prescription or non-prescription addiction; (b) opioid addiction or another addiction; (c) the amount of family social support of a family member who has ongoing interactions with the individual struggling with addiction; and (d) stress of the family member in a rural area. Bowen’s family systems theory provided the theoretical framework for the study. A non-probability …

A Topological Route To Engineering Robust And Bright Supersymmetric Laser Arrays, Soujanya Datta, Mohammad Alizadeh Fard, Ramy El-Ganainy, Krishanu Roychowdhury

Michigan Tech Publications

In recent years, several proposals that leverage principles from condensed matter and high-energy physics for engineering laser arrays have been put forward. The most important among these concepts are topology, which enables the construction of robust zero-mode laser devices, and supersymmetry (SUSY), which holds the potential for achieving phase locking in laser arrays. In this work, we show that the relation between supersymmetric coupled bosonic and fermionic oscillators on one side, and bipartite networks (and hence chiral symmetry) on another side can be exploited together with non-Hermitian engineering for building one- and two-dimensional laser arrays with in-phase synchronization. To demonstrate …

Multi-Antigen Elephant Endotheliotropic Herpesvirus (Eehv) Mrna Vaccine Induces Humoral And Cell-Mediated Responses In Mice, Rongsheng Peng, Jie Tan, Paul D Ling

Faculty, Staff and Students Publications

Background/Objectives: Elephant endotheliotropic herpesvirus (EEHV) causes lethal hemorrhagic disease (HD) in Asian and African elephants in human care and the wild. It is the leading cause of death for young Asian elephants in North American and European zoos despite sensitive diagnostic tests and improved treatments. Thus, there is a critical need to develop an effective vaccine to prevent severe illness and reduce mortality from EEHV-HD. We generated a multi-antigenic EEHV mRNA vaccine to address this need that encodes the EEHV1A-subtype glycoproteins gB, gH, gL, and gO. These conserved proteins are the entry machinery for several herpesviruses in the betaherpesvirus subfamily …

Distinct Effects Of Extra- And Intracellular Trehalose Supplementation In Freezing Medium On The Post-Thaw Developmental Capacity Of Feline Oocytes, Saengtawan Arayatham, Wirakan Kallayanathum, Panuwat Padungros, Theerawat Tharasanit

The Thai Journal of Veterinary Medicine

Oocyte cryopreservation is a crucial technique for preserving the genetic material of female cats, yet maintaining post-thaw oocyte developmental competence remains a significant challenge. This study investigated the impact of intra- and extracellular trehalose on the developmental competence of feline oocytes following cryopreservation. In Experiment 1, immature feline oocytes were matured in vitro (IVM) with varying concentrations (0, 1.5, and 3 mM) of intracellular trehalose hexaacetate (Tre-(OAc)6). The matured oocytes were then cryopreserved and thawed prior to in vitro fertilization and embryo culture. Experiment 2 examined the effects of extracellular trehalose supplementation at concentrations of 0, 0.125, 0.25, and 0.5 …

The Four Domains Model Of Artificial Intelligence In Surgical Education: Adapting Applications To Trainee Level, Anant R. Tewari, Jasraj Raghuwanshi, Lawal A. Labaran, Xudong Li

Journal of Innovation in Health Sciences Education

Since the inception of modern medicine, surgical trainees have benefitted from coaching and feedback from senior surgeons. In the high-demand operating room environment, granular feedback is often limited by time constraints. Artificial intelligence (AI) represents a novel frontier in surgical education in that it may be able to provide reliable, objective, and comprehensive feedback in an automated manner. While prior studies have given broad overviews of AI in surgical training, there has been no study to our knowledge that has codified the myriad applications and offered guidance for which applications best suit trainees at various levels of surgical education. We …