Digital Commons Network^™

Corporate Climate Targets: Science, Discretion, And Climate-Washing, Nadav Orian Peer

Publications

The use of corporate climate targets has exploded in recent years and now encompasses many of the world's largest and most profitable companies. In a corporate climate target, a company voluntarily commits to reducing its emissions in line with climate science and the Paris Agreement. The broad adoption of these targets raises important questions: are these commitments truly aligned with science in the way they are advertised, or do they raise "climate-washing" concerns; i.e., do they exaggerate the benefits and significance of the climate targets? This Article investigates the role that science actually plays within targets and explores different types …

From Gods To Google, Rebecca Aviel, Margot Kaminski, Toni M. Massaro, Andrew Keane Woods

Publications

The First Amendment has become a significant barrier to sensible technology regulation. The conventional explanation for this is the Court's deregulatory turn in free-speech law. But the Lochnerization story is incomplete. The Court's profound solicitude for religious speakers plays a central role in the current digital-free-expression landscape. By protecting the speech of certain religious dissidents, the Court has created a set of constitutional entitlements that logically extend to technology firms. Along the way, the Court has eroded its ability to apply the First Amendment sensibly to novel technologies.

This Feature draws the doctrinal through line from gods to Google. We …

Teaching At The Intersection Of Federal Indian Law And Environmental Law Courses, Mia Montoya Hammersley, Vanessa Ann Racehorse, Heather Tanana, Nadine Padilla, Gerald Torres

Publications

A discussion of the important role of Federal Indian Law in the practice of environmental and natural resources law and guidance on incorporating this intersection into traditional environmental law courses and curricula.

What Copyright Can't Do, Blake Reid

Publications

Copyright has become a powerful regulatory regime for modern American life. Copyrighted works, including text, images, video, sounds, music, and software, coupled with routine, frictionless copying, form a large part of the information, cultural and social context, and infrastructure of our increasingly digital society. Copyright law's powerful remedies are now positioned to intervene in a wide range of everyday activities. As a result, scholars, policymakers, and advocates have increasingly called for modifying and applying U.S. copyright law to solve a wide range of public policy problems, from vindicating disability rights to protecting privacy to promoting competition among wireless carriers.

But …

Transitioning To Regenerative Agriculture: One "Net-Zero" Pledge At A Time, Alexia Brunet Marks

Publications

As climate change intensifies, food sector multinational companies (MNCs), like Nestlé; Mars, Inc.; Unilever; PepsiCo; and Danone, face increasing pressure to reach net-zero by 2050, whereby they would reduce and ultimately eliminate carbon dioxide emissions from their supply chains by 2050. Carbon dioxide emissions are a major business liability, decreasing a firm’s value an average of $212,000 for every one thousand metric tons produced. As companies seek to align their pledges with regional, national, and subnational climate goals, they are legally required to comply with a growing number of disclosure rules for foods entering the United States and the European …

Unwritten Administrative Law And The Regulatory Last Mile, Anthony B. Derron

Publications

Programs like the Clean Water Act, Clean Air Act, and Resource Conservation and Recovery Act are ostensibly federal. But once they change hands from national to subnational, they’re implemented through state statutes and regulations, not direct enforcement of the United States Code. As a result, state, not federal, administrative law governs in many bread-and-butter situations. Through a comprehensive fifty-state survey, I find that this body of law is largely unwritten.

Yet cooperative federalism relies on the capacity of state institutions to function. And equally critical is the existence of law that shepherds a program from congressional subcommittee to the very …

Nist's Software Un-Standards, Bryan H. Choi

Publications

The National Institute of Standards and Technology (NIST) has become a beacon of hope for those who trust in federal standards for software and AI safety. Moreover, lawmakers and commentators have indicated that compliance with NIST standards ought to shield entities from liability. With more than a century of expertise in scientific research and standard setting, NIST would seem to be uniquely qualified to develop such standards.

But as I argue in this Article, this faith is misplaced. NIST’s latest forays in risk management frameworks disavow concrete metrics or outcomes, and solicit voluntary participation instead of providing stable mandates. That …

In Vitro Comparative Study Of Composite Coatings For Magnesium-Based Bone Implants, Abdelrahman Amin, Bryce Williams, Thomas Mcgehee, Alyssandra Navarro, Vipul Patil, Mostafa Elsaadany, Hanna Ibrahim

Biomedical Engineering Faculty Publications and Presentations

This study provides a comparative assessment of the corrosion, morphology, and biological properties of four of the most promising coating methods for magnesium in biomedical applications, namely micro-arc oxidation (MAO), graphene oxide (GO)-containing MAO coating, MAO/sol-gel composite coating, and MAO/polycaprolactone (PCL) polymer dip coating approaches. Despite the abundance of research focused on these promising coating approaches, there is a notable lack of comparative studies evaluating their properties. To this end, the investigated composite coatings are ZK60+MAO, ZK60+MAO/GO, ZK60+MAO/Sol-gel, and ZK60+MAO/PCL composite coating. Several tests were used to assess various properties of the prepared groups such as in vitro corrosion characteristics, …

Addressing The Barriers To Peritoneal Dialysis-Visual Appeal Matters, Sam Stephens, Larissa Whale, Makenzie Kapales, Fatima Ayub, Morten O. Jensen, Manisha Singh

Biomedical Engineering Faculty Publications and Presentations

Peritoneal dialysis (PD) is an effective renal replacement strategy for patients with end-stage renal disease utilizing the peritoneum as the filter and PD catheter as access. A survey of PD patients showed that some felt uncomfortable with the length of current catheters and would be interested to explore newer, shorter designs. We redesigned the transfer set and external portion of the catheter, addressing this barrier as a part of our multi-institutional design project led by a nephrologist from the University of Arkansas for Medical Sciences (UAMS) and an engineering design team from the biomedical engineering department at the University of …

What's The Harm In (Partisan) Gerrymandering? Collective Vs. Dyadic Accounts Of Representational Disparities, Sanford C. Gordon, Douglas M. Spencer, Sidak Yntiso

Publications

Traditional approaches for documenting the harm of gerrymandering emphasize collective representation by legislatures, minimizing the relationship between individual voters and their respective representatives. Federal courts have struggled to map collective accounts onto cognizable constitutional harms, reflecting a discomfort evaluating a system of representation inescapably rooted in geographic districts using diagnostics that treat districts and their boundaries as an inconvenience rather than an intrinsic feature. A normative account of representation and accountability rooted in the dyadic relationship between voters and their legislators addresses the exact harms that courts have articulated yet struggled to substantiate. We derive a formal model of dyadic …

Securitizing The University, Maryam Jamshidi

Publications

Since October 7, 2023, public and private actors have doubled down on efforts to securitize the American university. In large part, these initiatives aim to quash a vocal pro-Palestine movement that has become highly visible across U.S. campuses since October 7th. In targeting this group, these efforts have variously treated the university as an "object" of national security, namely, as a potential site of national security risk, while simultaneously encouraging or pressuring universities to "participate" in national security, namely, by actively and, in many cases, voluntarily furthering U.S. national security objectives. The university's status as object of and participant in …

The Legitimation Of Shareholder Primacy, Ann Lipton

Publications

We are living in a polarized era, and corporate governance is no exception. With controversies raging over "environmental, social, governance," (ESG) investing, diversity, equity and inclusion initiatives, climate change as an investment concern, and even Elon Musk's pay package at Tesla, it seems as though corporate governance has never been so starkly divided along partisan lines.

The divisions have threatened to spill over to Delaware, the preferred jurisdiction for incorporation in the United States. Several high profile cases—including those involving Elon Musk—have called Delaware's neutrality into question. Commenters have argued that Delaware's newly politicized approach threatens to splinter the corporate …

Tainted Source Code, Bryan H. Choi

Publications

Open-source software has long eluded tort liability. Fierce ideological commitments and sticky license terms support a long tradition of forbearance against penalizing harmful or negligent work in open-source communities. The free, noncommercial, distributed, and anonymous characteristics of open-source contributions present additional obstacles to legal enforcement.

The exponential rise in software supply chain attacks has given new urgency to the problem of bad open-source code. Yet, current approaches are unlikely to meaningfully improve open-source security and safety. On the one hand, technological tools and self-governance mechanisms remain woefully underdeveloped and underutilized. On the other hand, liability proposals that place all the …

The Dna Demethylase Tet1 Modifies The Impact Of Maternal Folic Acid Status On Embryonic Brain Development, Spyridon Champeris Tsaniras, Wannes Brangers, Harm H M Kwak, Rita Khoueiry, Yunping Lei, Robert Cabrera, Steven S Gross, Richard H Finnell, Kian Peng Koh

Faculty, Staff and Students Publications

Folic acid (FA) is well known to prevent neural tube defects (NTDs), but we do not know why many human NTD cases still remain refractory to FA supplementation. Here, we investigate how the DNA demethylase TET1 interacts with maternal FA status to regulate mouse embryonic brain development. We determined that cranial NTDs display higher penetrance in non-inbred than in inbred Tet1−/− embryos and are resistant to FA supplementation across strains. Maternal diets that are either too rich or deficient in FA are linked to an increased incidence of cranial deformities in wild type and Tet1+/− offspring and to …

Testing The Antigenic Potential Of Transmembrane Proteins To Develop A Thermostable Tuberculosis Mof-Liposomal Vaccine, Sneha Kumari, Jonathan Martinez-Garcia, Ryanne Nicole Ehrman, Wendy Tang, Joshua Miles, Priyanka Basak, Thomas Sinclair Howlett, Yalini Hansika Wijesundara, Ziqi Wang, Blanca I. Restrepo

School of Medicine Publications

Tuberculosis is one of the deadliest infectious diseases and continues to be a major health risk in many parts of the world. Even today, the century-old Bacillus Calmette-Guerin (BCG) vaccine is the only formulation on the market and is ineffective for several sections of the global population responsible for transmission. In the search for antigens that can mount a robust immune response, we have reported the recombinant expression and purification of two novel membrane proteins, the Cation transporter protein V (CtpV) and the Mycobacterial copper transporter B (MctB) present on the membrane surface of Mycobacterium tuberculosis. CtpV was tested …

Autonomic Dysfunction In Gastroesophageal Reflux Disease. The Neurogastro-Cardiac Axis: Friend Or Foe?, Sergio Sobrino-Cossio, Jorge Cossío-Aranda, Elymir S. Galvis-García, Gualberto Mateos-Pérez, Óscar Teramoto-Matsubara, Jesús A. González-Hermosillo, Juan C. Lopez Alvarenga, Mustafa Azizoglu, José M. Remes-Troche

School of Medicine Publications

Gastroesophageal reflux disease (GERD) is a complex and highly prevalent entity. Impaired gut-brain communication is associated with autonomic dysfunction. Modulation of the autonomic nervous system controls gastrointestinal functions. In GERD, a decrease in vagal tone (parasympathetic activity) and an increase in sympathetic activity with autonomic balance shifted towards the sympathetic system have been reported. Clinical questionnaires and non-invasive measurement of heart rate variability may be useful in patients with GERD to detect autonomic dysfunction. Restoration of parasympathetic system activity (mainly neuromodulation), with subsequent improvement of parasympathetic activity, will reduce the intensity of autonomic symptoms and GERD, improving quality of life. …

Annual Town Report, Errol New Hampshire, Year Ending December 31, 2024. Annual Errol School District Report Fiscal Year Ending June 30, 2024, Errol Town Representatives

Errol, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Seasonal Variability Of Surface Ocean Carbon Uptake And Chlorophyll-A Concentration In The West Antarctic Peninsula Over Two Decades, Jessica S. Turner, David R. Munro, Amanda Fay, Sharon Stammerjohn, Heather Kim, Oscar Schofield, Heidi Dierssen

OES Faculty Publications

The Southern Ocean plays a vital role in global CO₂ uptake, but the magnitude and even the sign of the flux remain uncertain, and the influence of phytoplankton phenology is underexplored. This study focuses on the West Antarctic Peninsula, a region experiencing rapid climate change, to examine shifts in seasonal carbon uptake. Using 20 years of in situ air-sea CO₂ flux and satellite-derived Chlorophyll-a, we observe that the seasonal cycles of both air-sea CO₂ flux and Chlorophyll-a intensify poleward. The amplitude of the seasonal cycle of the non-thermal component of surface ocean pCO₂ increases with increasing latitude, while the amplitude …

Sandy Subterranean Estuaries Minimize Groundwater Nitrogen Pollution Impacts On Coastal Waters, Xiaogang Chen, Isaac R. Santos, Jinzhou Du, Bochao Xu, Joseph J. Tamborski, Ding He, Neven Cukrov, Christian J. Sanders, Jianan Liu, Peiyuan Zhu, Yan Zhang, Ling Li

OES Faculty Publications

Widespread anthropogenic activities pollute groundwater that eventually seeps out to the coastal ocean. Here, we resolve nutrient transformations and fluxes in 11 sandy subterranean estuaries (STEs) with contrasting nutrient sources and development trajectories. Coastal groundwater nitrogen pollution stems from sewage discharge and land use change. Anthropogenically derived groundwater nutrient fluxes with high N/P ratios (∼170) accounted for 22%–61% of riverine inputs into China's coastal waters, providing an additional source of nutrients that can fuel coastal eutrophication and algal blooms. Sandy STEs remarkably attenuated ∼84% of nitrogen pollution, minimizing the impact of submarine groundwater discharge (SGD) on coastal water quality. Hence, …

Seasonality Of Submarine Groundwater Discharge Pathways In A Coastal Lagoon Revealed By Radium Isotopes: The Importance Of Porewater Exchange In Summer, Júlia Rodriguez-Puig, Valentí Rodellas, Marc Diego-Feliu, Andres Alcolea, Joaquín Jiménez-Martínez, Irene Alorda-Montiel, Aaron Alorda-Kleinglass, Francisco Pereira, Marisol Manzano, Javier Gilabert, Jordi Garcia-Orellana

OES Faculty Publications

Chemical fluxes supplied by Submarine Groundwater Discharge (SGD) can be relevant for coastal ecosystems, particularly lagoonal environments. An appropriate understanding of SGD requires constraining the magnitude and composition of its different pathways. However, the evaluation of SGD pathways is often limited to independent estimations, lacking a comprehensive understanding of the groundwater processes at play. In this study, we combined a Ra mass balance and hydrogeological modeling to simultaneously estimate different SGD pathways flowing into a coastal lagoon. We assessed water fluxes derived from fresh SGD, long-scale recirculation of seawater, and porewater exchange (PEX) into Mar Menor, a highly anthropized coastal …

Optimizing An Image Analysis Protocol For Ocean Particles In Focused Shadowgraph Imaging Systems, Huanqing Huang, Alexander B. Bochdansky

OES Faculty Publications

A variety of imaging systems are in use in oceanographic surveys, and the opto-mechanical configurations have become highly sophisticated. However, much less consideration has been given to the accurate reconstruction of imaging data. To improve reconstruction of particles captured by Focused Shadowgraph Imaging (FoSI)—a system that excels at visualizing low-optical-density objects, we developed a novel object detection algorithm to process images with a resolution of ~ 12 μm per pixel. Suggested improvements to conventional edge-detection methods are relatively simple and time-efficient, and more accurately render the sizes and shapes of small particles ranging from 24 to 500 μm. In addition, …

From Wind To Whales: Potential Hydrodynamic Impacts Of Offshore Wind Energy On Nantucket Shoals Regional Ecology, Eileen E. Hofmann, Jeffrey R. Carpenter, Qin J. Chen, Josh T. Kohut, Richard L. Merrick, Erin L. Meyer-Gutbrod, Douglas P. Nowacek, Kaustubha Raghukumar, Nicholas R. Record, Kelly Oskvig

OES Faculty Publications

The National Academy of Sciences, Engineering, and Medicine convened a committee in June 2023 to assess the potential hydrodynamic and ecological impacts from offshore wind energy development in the Nantucket Shoals region, with particular attention to impacts on the critically endangered North Atlantic right whale (Eubalaena glacialis) that forages on zooplankton aggregations in the region. The assessment suggested that the effects of offshore wind energy development will be difficult to distinguish from the effects of natural variability and climate change in this region. The Consensus Study Report recommendations highlight observational and modeling studies that will advance understanding of …

A Century Of Sediment Metal Contamination Of Mar Menor, Europe's Largest Saltwater Lagoon, Irene Alorda-Montiel, Valentí Rodellas, Ariane Arias-Ortiz, Albert Palanques, Andrea G. Bravo, Júlia Rodriguez-Puig, Aaron Alorda-Kleinglass, Carlos Green-Ruiz, Marc Diego-Feliu, Pere Masqué, Javier Gilabert, Jordi Garcia-Orellana

OES Faculty Publications

Coastal enclosed ecosystems, such as lagoons, are vulnerable to anthropogenic impacts because they favor the accumulation of contaminants from the surrounding watersheds, particularly in their sediments. Europe's largest saltwater lagoon, the Mar Menor (SE, Iberian Peninsula), is a highly impacted ecosystem and the first in the continent to be granted personhood rights. Based on a high-resolution spatial and temporal dataset, we present the historical reconstruction of metal contamination in this ecosystem during the last century. Our results highlight that sediment metal contamination has been mainly driven by the development of the mining industry in the nearby Sierra Minera de Cartagena-La …

Ensemble Machine Learning Approaches For Bathymetry Estimation In Multi-Spectral Images, Kazi A. Islam, Omar Abdul-Hassan, Hongfang Zhang, Victoria Hill, Blake Schaeffer, Richard Zimmerman, Jiang Li

OES Faculty Publications

Traditional bathymetry measures require a large number of human hours, and many bathymetry records are obsolete or missing. Automated measures of bathymetry would reduce costs and increase accessibility for research and applications. In this paper, we optimized a recent machine learning model, named CatBoostOpt, to estimate bathymetry based on high-resolution WorldView-2 (WV-2) multi-spectral optical satellite images. CatBoostOpt was demonstrated across the Florida Big Bend coastline, where the model learned correlations between in situ sound Navigation and Ranging (Sonar) bathymetry measurements and the corresponding multi-spectral reflectance values in WV-2 images to map bathymetry. We evaluated three different feature transformations as inputs …

Unveiling Hidden Mercury And Methylmercury Sources: The Role Of Submarine Groundwater Discharge In Coastal Lagoons, Céline Lavergne, Júlia Rodriguez-Puig, Clara Ruiz-González, Maria Montero-Curiel, Gemma Casas, Daniel Romano-Gude, Irene Alorda-Montiel, Júlia Dordal-Soriano, Aaron Alorda-Kleinglass, Marc Diego-Feliu, Javier Gilabert, Alex Campillo-De La Maza, Cristina Romera-Castillo, Natalia Torres-Rodriguez, Lars-Eric Heimbürger-Boavida, Jordi Garcia-Orellana, Valenti Rodellas, Andrea G. Bravo

OES Faculty Publications

Mercury loads from Submarine Groundwater Discharge (SGD) may represent an overlooked source of methylmercury (MeHg) to the ocean, affecting human and ecosystem health. The SGD process involves the flow of fresh, saline, or mixed groundwater from coastal aquifers into the oceans classified in different components. Existing studies rarely report the fluxes supplied by the different SGD components; therefore, the relevance of SGD as a source of mercury remains unclear. We aimed to quantify SGD-driven mercury/methylmercury fluxes to the coast, focusing on the largest coastal lagoon in the western Mediterranean. We measured total dissolved mercury and MeHg in surficial and porewaters …

Dynamics Of Water Mass Exchange Across The Central Ross Sea Slope, Yuanjie Chen, Zhaoru Zhang, Pasquale Castagno, Xianxian Han, Michael S. Dinniman, Zhiqiang Liu, Chuning Wang

OES Faculty Publications

The central Ross Sea slope (CRSS) is a critical region for water mass exchange, significantly influencing the physical and biological processes of the Ross Sea shelf and the global overturning circulation. This study utilizes a high-resolution ocean-ice shelf-sea ice coupled model to investigate the mechanisms driving this exchange, involving the onshore transport of circumpolar deep water (CDW) and the offshore transport of dense shelf water (DSW). Combining numerical simulations and mooring observations, this work reveals high-frequency oscillations with a periodicity of ∼32 hr in CDW transport induced by Topographic Rossby Waves and DSW transport induced by cyclonic eddies. These findings …

Impact Of Submarine Groundwater Discharge On Microbial Communities In A Highly Anthropized Coastal Lagoon (Mar Menor, Se Spain), Daniel Romano-Gude, Júlia Dordal-Soriano, Júlia Rodriguez-Puig, Andrea G. Bravo, Irene Alorda-Montiel, Aaron Alorda-Kleinglass, Marc Diego-Feliu, Cristina Romera-Castillo, Rebeca Mallenco-Fornies, Javier Gilabert, Jordi Garcia-Orellana, Valentí Rodellas, Clara Ruiz-González

OES Faculty Publications

Submarine groundwater discharge (SGD) supplies large quantities of nutrients and other terrestrial elements to coastal ecosystems, impacting marine biota and ecosystem functioning. Despite the relevance of prokaryotes for marine biogeochemistry, little is known about their responses to groundwater inputs. Here we explored the impact of SGD on the spatiotemporal patterns of prokaryotic communities from the Mar Menor (Murcia, Spain), a highly anthropized hypersaline coastal lagoon that receives large amounts of nutrient-polluted SGD. Using 16S rRNA amplicon sequencing, activity assays, and flow cytometry, we investigated the dynamics of prokaryotic communities across the lagoon and its connected environments (freshwater streams, groundwater, soils, …

Goldenbraid20 E Coli: A Comprehensive And Characterized Toolkit For Enterics, Alice X Wen, David C Marciano, Christophe Herman

Faculty, Staff and Students Publications

Modular cloning systems streamline laboratory workflows by consolidating genetic 'parts' into reusable and modular collections, enabling researchers to fast-track strain construction. The GoldenBraid 2.0 modular cloning system utilizes the cutting property of type IIS restriction enzymes to create defined genetic 'grammars', which facilitate the reuse of standardized genetic parts and assembly of genetic parts in the right order. Here, we present a GoldenBraid 2.0 toolkit of genetic parts designed to accelerate cloning in the model bacterium

Research For All: Building A Diverse Researcher Community For The All Of Us Research Program, Jessica Lee, Faith Blackburne-Proctor, Romuladus Azuine, Nakia Mack, Sheri D Schully, Martin Mendoza, Janeth Sanchez, Yong Crosby, Erica Zumba, Michael Hahn, Naomi Aspaas, Ahmed Elmi, Shanté Alerté, Elizabeth Stewart, Danielle Wilfong, Meag Doherty, Margaret M Farrell, Grace B Hébert, Sula Hood, Cheryl M Thomas, Debra D Murray, Brendan Lee, Louisa A Stark, Megan A Lewis, Jen D Uhrig, Laura R Bartlett, Edgar Gil Rico, Adolph Falcón, Elizabeth Cohn, Mitchell R Lunn, Juno Obedin-Maliver, Linda Cottler, Milton Eder, Fornessa T Randal, Jason Karnes, Kitani Lemieux, Nelson Lemieux, Nelson Lemieux, Lilanta Bradley, Ronnie Tepp, Meredith Wilson, Monica Rodriguez, Chris Lunt, Karriem Watson

Faculty, Staff and Students Publications

OBJECTIVES: The NIH All of Us Research Program (All of Us) is engaging a diverse community of more than 10 000 registered researchers using a robust engagement ecosystem model. We describe strategies used to build an ecosystem that attracts and supports a diverse and inclusive researcher community to use the All of Us dataset and provide metrics on All of Us researcher usage growth.

MATERIALS AND METHODS: Researcher audiences and diversity categories were defined to guide a strategy. A researcher engagement strategy was codeveloped with program partners to support a researcher engagement ecosystem. An adapted ecological model guided the ecosystem …

Modeling Functional Connectivity With Learning And Memory In A Mouse Model Of Alzheimer’S Disease, Jonathan Romero, Caitlyn Ortiz, Eric Shin, Md Abul Hassan Samee, Robia G Pautler

Faculty, Staff and Students Publications

Introduction: Functional connectivity (FC) is a metric of how different brain regions interact with each other. Although there have been some studies correlating learning and memory with FC, there have not yet been, to date, studies that use machine learning (ML) to explain how FC changes can be used to explain behavior not only in healthy mice, but also in mouse models of Alzheimer's Disease (AD). Here, we investigated changes in FC and their relationship to learning and memory in a mouse model of AD across disease progression.

Methods: We assessed the APP/PS1 mouse model of AD and wild-type controls …