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Inpatient Vs. Outpatient Management Outcomes Of Ectopic Pregnancy With Methotrexate, Courtney Smith, Taryn Hoffman, Kavya Davuluri, Ashley Brodrick, Taylor Penny, Robyn Meadows, Martin Wegman Jan 2025

Inpatient Vs. Outpatient Management Outcomes Of Ectopic Pregnancy With Methotrexate, Courtney Smith, Taryn Hoffman, Kavya Davuluri, Ashley Brodrick, Taylor Penny, Robyn Meadows, Martin Wegman

South Atlantic Division GME Research Day 2025

No abstract provided.


Flame Boundary Effects Of Hydrogen-Air Premixing, Alecson L. De Lima Junior Jan 2025

Flame Boundary Effects Of Hydrogen-Air Premixing, Alecson L. De Lima Junior

Honors Undergraduate Theses

The objective of this research was to investigate the reaction of hydrogen and heated air premixing when injected into a combusting ethylene-air crossflow, and to study the flame stabilization location with varying premixing levels. The main parameter of this investigation was the flame stabilization diagnosed through chemiluminescence, based on recorded equivalence ratio, temperature, and flame boundaries, and maintaining a constant air temperature, hydrogen and air mass flow, and momentum flux ratios. Testing was conducted at different ratios of hydrogen and air premixing achieved through alternating the distance between the point where hydrogen and air are mixed and the combusting crossflow. …


Selecting For Lysis In A Temperate Phage Population, Haley Atkins Jan 2025

Selecting For Lysis In A Temperate Phage Population, Haley Atkins

Dissertations

The ongoing evolutionary arms race between bacteria and bacteriophages (phages) is a prime example of Red Queen hypothesis, where continuous adaptation drives survival. This study focuses on Escherichia coli-infecting temperate phages, which dominate natural environments and contribute to bacterial resistance mechanisms. Despite their prevalence, temperate phages are less suited for phage therapy due to their lysogenic life cycle, where they integrate into bacterial genomes instead of lysing the host. In contrast, obligately lytic phages, which directly lyse bacterial cells, are ideal for therapeutic use but occur less frequently in nature. This research aims to select for lytic behavior in temperate …


What Makes A Teacher A Teacher: A Philosophical Approach Aligned With Plato, Sojung Kim Hinterkopf Jan 2025

What Makes A Teacher A Teacher: A Philosophical Approach Aligned With Plato, Sojung Kim Hinterkopf

Dissertations

This thesis investigates how contemporary U.S. educational accountability policies—namely No Child Left Behind (NCLB) and Race to the Top (RttT)—redefine the role of teachers through a compliance-oriented lens. Moving beyond logistical and emotional impacts, this study applies Plato’s Allegory of the Cave as a philosophical framework to uncover the intellectual and ethical constraints imposed on educators. Through qualitative document analysis of federal policy texts, three metaphorical themes—shackles, shadows, and enlightenment—emerged to represent how teachers are bound by data-driven mandates, compelled to perform surface-level success, and yet still retain the potential to guide students toward deeper intellectual engagement. The findings reveal …


Anti-Inflamatory Mechansim Of Bacillus Subtilis Derirved Exopolysaccharide, Adrian Taylor Ibarra Jan 2025

Anti-Inflamatory Mechansim Of Bacillus Subtilis Derirved Exopolysaccharide, Adrian Taylor Ibarra

Dissertations

Exopolysaccharides (EPS) secreted by the commensal bacterium Bacillus subtilis exhibit potent anti-inflammatory properties, yet the underlying molecular mechanisms remain incompletely understood. We hypothesized that EPS reprograms antigen-presenting cells toward a tolerogenic state by modulating TLR4–MyD88 signaling. To test this, we began using a chemically defined, high-yield EPS production and purification protocol that largely eliminates protein and DNA contaminants, thus improving functional reproducibility across experiments using this new method. In vitro, EPS engaged TLR4 on murine dendritic cells (DC2.4) without inducing classical NF-κB activation, seen by LPS stimulation. Rather, EPS treatment upregulated inhibitory molecules, PD-L1 and PD-L2 while leaving activation markers, …


Developing Chemically Defined Serum-Free Medium For Leukemic Blast And Stem Cell Expansion, Carmen Eva Finley Jan 2025

Developing Chemically Defined Serum-Free Medium For Leukemic Blast And Stem Cell Expansion, Carmen Eva Finley

Dissertations

The relapse and chemotherapy resistance are the major challenges of acute myeloid leukemia (AML) treatment, driven by a rare population of leukemia stem cells (LSCs). LSCs are unique types of cells which evade standard chemotherapies and can regenerate AML post-treatment. Targeting LSC therapy remains limited, in part due to the lack of reliable in vitro AML culture systems to grow LSCs for drug discovery. This study aimed to engineer a chemically defined, serum-free 2D in vitro culture condition that supports either the expansion of leukemic blasts (LBs) or primary human LSCs by optimizing current protocols for hematopoietic stem cells (HSCs) …


“What’S Happening In The Gulf Of Maine?”: Middle School Students’ Engagement In Climate Science Through Data Visual Representation And Reflections, Grace Ocular Jan 2025

“What’S Happening In The Gulf Of Maine?”: Middle School Students’ Engagement In Climate Science Through Data Visual Representation And Reflections, Grace Ocular

Dissertations

This study examined how middle school students engaged with science concepts while working with data visualizations during a field trip learning experience. Fifty-one teams of 2–4 students from 35 schools participating in the LabVenture program were video- and audio-recorded. Students completed two activities: one using a frequency table of marine species illustrating threats to Maine’s lobster population, and another using maps depicting changes in Gulf of Maine sea surface temperature. After each activity, students annotated the visualization, discussed their claims, and recorded short reflections. Transcripts were coded for science-related talk, and annotations and gestures were also analyzed. Findings indicate that …


Episodes In Computing History - Salon Talk, George K. Thiruvathukal Jan 2025

Episodes In Computing History - Salon Talk, George K. Thiruvathukal

Computer Science: Faculty Publications and Other Works

This talk (first given in 2004) presents a concise overview of key developments in the history of computing. It begins with early methods of counting and recordkeeping, such as tally sticks and the Inca quipu. It then traces the evolution of numeric systems, including Roman and Hindu-Arabic notation, and the mathematical contributions of figures like Al-Khwarizmi. Mechanical computing devices such as the abacus, Napier’s bones, and the Pascaline are examined, along with the Jacquard loom and its use of punch cards.

The talk continues through the rise of electronic computing, highlighting milestones such as ENIAC, the work of Alan Turing, …


Cultivating Community-University Partnerships Within The Chicago Region Food System, Hanan Abdillahi, Vivian Cossey, Tania Schusler, Kevin Erickson, Karen Schauwecker, Sarah Ku, Ray Dybzinski Jan 2025

Cultivating Community-University Partnerships Within The Chicago Region Food System, Hanan Abdillahi, Vivian Cossey, Tania Schusler, Kevin Erickson, Karen Schauwecker, Sarah Ku, Ray Dybzinski

School of Environmental Sustainability: Faculty Publications and Other Works

We interviewed 22 organizations in the Chicago Regional Food System to gain insights on their current initiatives, assets, challenges, future visions, and perceived roles of universities in advancing their work. We analyzed themes to report on strong consensus or varied perspectives related to this work. This report aims to advise Loyola’s School of Environmental Sustainability's future work and collaboration activities with Chicago Food System organizations.


Integrated Qfd-Triz Optimization Method For Satellite Solar Array Design In Cost-Sensitive Environment, Hongyi Zhang, Liang Su Jan 2025

Integrated Qfd-Triz Optimization Method For Satellite Solar Array Design In Cost-Sensitive Environment, Hongyi Zhang, Liang Su

International Journal of Aviation, Aeronautics, and Aerospace

With the rapid evolution of commercial space markets in the new space era, satellite design philosophy is transitioning from "performance supremacy" toward "cost-effectiveness priority." This research concentrates on solar arrays, a critical component representing 15%-20% of satellite costs, addressing limitations in traditional design methodologies that inadequately coordinate user requirements and lack systematic frameworks for cost-performance collaborative optimization. We propose a solar array optimization methodology predicated on the integration of Quality Function Deployment (QFD) and the Theory of Inventive Problem Solving (TRIZ). This methodology incorporates cost dimensions through an extended QFD matrix, employs TRIZ to resolve technical contradictions, and develops a …


Suas Agricultural Aerial Application Operational Field Test, David Thirtyacre, Joseph Cerreta, Scott S. Burgess Jan 2025

Suas Agricultural Aerial Application Operational Field Test, David Thirtyacre, Joseph Cerreta, Scott S. Burgess

International Journal of Aviation, Aeronautics, and Aerospace

One of the most promising uses of aerial applications by a sUAS is on small farms where traditional crewed aerial applicators were not practical due to the limited size of the operations. This controlled field test aimed to assess the feasibility and cost-effectiveness of using a sUAS spreading system compared to the traditional manual application of weed killer and fertilizer on cranberry bogs in Western Washington that were less than 10 acres. The aerial application took place over two separate days as scheduled by the farmer for maximum product efficiency. A total of sixty-three flights were necessary to apply the …


Bibliometric Analysis With R Biblioshiny On Safety Behavior In Aviation, Büşra Yıldırım, İnan Eryılmaz, Ahmet Karacan, Nusret Erceylan Jan 2025

Bibliometric Analysis With R Biblioshiny On Safety Behavior In Aviation, Büşra Yıldırım, İnan Eryılmaz, Ahmet Karacan, Nusret Erceylan

International Journal of Aviation, Aeronautics, and Aerospace

Safety behaviors in aviation are not limited to technical knowledge and skills in ensuring the safety of flight operations, but also include the attitudes, decision-making processes and collaborations of individuals and teams. In this context, in this study, a bibliometric analysis of publication and citation trends, key concepts and interactions of studies in the field was conducted to identify current and potential trends in aviation and safety behavior-based research, and to explore the intersections between safety behavior and aviation studies and the areas waiting to be explored. The bibliometric analysis using the RStudio-based Biblioshiny program was conducted on 1065 articles …


Evaluating The Reporting And Safety Culture Of An Airline According To Patankar And Sabin's Safety Culture Pyramid, Seda Mumlu Karanfil Jan 2025

Evaluating The Reporting And Safety Culture Of An Airline According To Patankar And Sabin's Safety Culture Pyramid, Seda Mumlu Karanfil

International Journal of Aviation, Aeronautics, and Aerospace

As a result of the literature review, it is seen that the safety management system in airline businesses is mostly evaluated with Reason's just culture model. The fact that there is no research examining Patankar and Sabin's (2010) safety culture pyramid on airline operations, except for a study conducted in the field of ground handling services (Poçar, Işık, & Durmaz, 2022), constitutes the importance and unique value of the research. As stated by Poçar et al. (2022), Patankar and Sabin's (2010) safety culture pyramid is not sufficiently included in practice, and this model is important in terms of drawing attention …


Mitigating Information Overload In Aviation Safety: Ai-Driven Hierarchical Tagging And Summarization Of Notam For Pre-Flight Information Bulletin, Rutong Gu, Yefeng Qu, Dongling Chen, Yu Tang, Ailin Zhou Jan 2025

Mitigating Information Overload In Aviation Safety: Ai-Driven Hierarchical Tagging And Summarization Of Notam For Pre-Flight Information Bulletin, Rutong Gu, Yefeng Qu, Dongling Chen, Yu Tang, Ailin Zhou

International Journal of Aviation, Aeronautics, and Aerospace

To address the challenges of aviation safety information overload in Pre-flight Information Bulletin (PIB) systems, this study proposes an intelligent classification framework (ERNIE-DPCNN) that integrates knowledge-enhanced semantic representation with a Deep Pyramid Convolutional Network. Traditional systems relying on rule-based filtering mechanisms suffer from inefficiencies in critical information identification and high risks of human misjudgment. The proposed framework achieves breakthroughs through three technical innovations: (1) An aviation domain-adapted ERNIE model is constructed, leveraging phrase-level masking strategies to enhance semantic representation of compound identifiers; (2) A Deep Pyramid Convolutional Network (DPCNN) is designed to extract multi-granularity features via hierarchical convolution-pooling architecture, optimized …


Innovative Bird Strike Mitigation Strategies: Integrating Drones And Cutting-Edge Technologies To Enhance Airport Safety, Abdellah Hanine, Abdellah Elbarkany Jan 2025

Innovative Bird Strike Mitigation Strategies: Integrating Drones And Cutting-Edge Technologies To Enhance Airport Safety, Abdellah Hanine, Abdellah Elbarkany

International Journal of Aviation, Aeronautics, and Aerospace

Notwithstanding significant efforts to reduce the risk of bird strikes at and around airports, as well as advancements in technology, aviation safety continues to be threatened by this hazard. Our study of recent data shows a clear historical increase in accidents, therefore underscoring the flaws in present technologies. Although among the technologies in common use are radar, drones, cameras, and acoustic approaches, they are not always able to completely meet the challenging needs of bird strike risk mitigation. This approach creatively blends these four fundamental technologies by means of enhanced real-time data processing and targeted drone deployment. While providing more …


Design, Implementation, And Testing Of Spatial Disorientation Scenarios In A Modified Hexapod Motion Simulator, Jarod Hinckley, Ryan Paul, Logan Rock, Joe Conner, Jon M. Loffi Jan 2025

Design, Implementation, And Testing Of Spatial Disorientation Scenarios In A Modified Hexapod Motion Simulator, Jarod Hinckley, Ryan Paul, Logan Rock, Joe Conner, Jon M. Loffi

International Journal of Aviation, Aeronautics, and Aerospace

Abstract

Investigations into aviation accidents aim to identify root causes and enhance safety. Despite advancements in safety measures, technology, and education, general aviation accident rates remain stable, with loss of control identified as the leading cause. Spatial disorientation is a significant contributing factor in these incidents, accounting for approximately 10% of general aviation accidents—90% of which are fatal. Addressing spatial disorientation is increasingly critical with the emergence of Advanced Air Mobility (AAM) vehicles, a sector projected to reach a $30 billion market by 2030. While AAM is expected to transition toward full autonomy, human pilots will operate these vehicles during …


Generalizing Classification Of Pilot Workload: Transfer Learning Versus A Jepa-Inspired Transformer Architecture, Naim Barnett, Shivani Nagrecha, Morgan Glover, Clayton Harper, Justin Wilson, James Maher, Eric C. Larson Jan 2025

Generalizing Classification Of Pilot Workload: Transfer Learning Versus A Jepa-Inspired Transformer Architecture, Naim Barnett, Shivani Nagrecha, Morgan Glover, Clayton Harper, Justin Wilson, James Maher, Eric C. Larson

International Journal of Aviation, Aeronautics, and Aerospace

Within the context of learning, there poses difficulty when objectively measuring human performance. In this work, we investigate the evaluation of human performance via its relation to the individual's mental capacity by classification of cognitive load within the domain of aviation. By utilizing a mixed virtual and physical flight simulation environment in conjunction with biometric sensing, we create and evaluate the predictive capabilities of a Joint-Embedding Predictive Architecture (JEPA) and compare the architecture and results to traditional methods for transfer learning and domain adaptation. We find that our JEPA inspired architecture can achieve more than 70% accuracy of cognitive workload, …


Dred Scott, Military Enslavement, And The Case For Reparations, Hugh Barrett Mcclean Jan 2025

Dred Scott, Military Enslavement, And The Case For Reparations, Hugh Barrett Mcclean

All Faculty Scholarship

For more than a decade, Dred Scott was enslaved by a U.S. Army officer in a military system that perpetuated the institution of slavery in the free states and Northern territories of the antebellum period. Scott’s life, his lawsuit for freedom, and the U.S. Supreme Court case holding that Black people have “no rights which the white man was bound to respect” became infamous. But the history of the Dred Scott case and the military’s use of enslaved persons is largely unknown. Drawing on reparations advocacy in the Rosewood and Tulsa race massacre cases and other historical precedent for reparations, …


Advances In Ocean Mapping And Nautical Cartography, Giuseppe Masetti, Ian Church, Anand Hiroji, Ove Andersen Jan 2025

Advances In Ocean Mapping And Nautical Cartography, Giuseppe Masetti, Ian Church, Anand Hiroji, Ove Andersen

Center for Coastal and Ocean Mapping

The Special Issue of Geomatics on "Advances in Ocean Mapping and Nautical Cartography" addresses emerging methodologies, technologies, and applications in ocean mapping. This collection includes studies on the development of high-resolution seabed mapping techniques, innovative data processing for marine cartography, and advancements in hydrographic surveying. It highlights the importance of integrating geospatial data from sources such as remote sensing, autonomous underwater vehicles, and satellite-based observations. Additionally, articles discuss challenges and strategies for ensuring data accuracy and accessibility, reflecting a growing interest in sustainable marine resource management and navigation safety enhancements.


Unh/Noaa Joint Hydrographic Center 2025 Performance And Progress Report Executive Summary, Larry A. Mayer Jan 2025

Unh/Noaa Joint Hydrographic Center 2025 Performance And Progress Report Executive Summary, Larry A. Mayer

Center for Coastal and Ocean Mapping

No abstract provided.


Unh/Noaa Joint Hydrographic Center 2025 Performance And Progress Report Executive Summary, Larry A. Mayer Jan 2025

Unh/Noaa Joint Hydrographic Center 2025 Performance And Progress Report Executive Summary, Larry A. Mayer

Center for Coastal and Ocean Mapping

Reporting Period: 01/01/2025–12/31/2025


Calcium Carbonate Microparticles As Acid Responsive Targeted Drug Delivery Carriers For Oral Diseases And Its Anti-Bacterial Activity, Hem Raj Joshi Jan 2025

Calcium Carbonate Microparticles As Acid Responsive Targeted Drug Delivery Carriers For Oral Diseases And Its Anti-Bacterial Activity, Hem Raj Joshi

Dissertations and Theses

Dental diseases are mostly caused by bacterial infections in the teeth, forming biofilms that release acids and decay the enamel of the teeth. More than half of the world's population were affected by oral diseases, including periodontitis (gum disease), dental caries (cavities), and oral cancer. Chlorhexidine (CHX) is the mostly used antimicrobial drug for dental diseases, but its overexposure to the healthy teeth causes many side effects, such as tooth staining, taste alteration, and many more. Taking advantage of the acidic environment of infected teeth, we designed a pH responsive targeted drug delivery system using calcium carbonate microparticles (CCMPs) as …


Convergence In Cancer: Integrative Multi-Modal Modeling For Pan-Cancer Drug Response Prediction, Jessica Zylla Jan 2025

Convergence In Cancer: Integrative Multi-Modal Modeling For Pan-Cancer Drug Response Prediction, Jessica Zylla

Dissertations and Theses

Heterogeneity and rarity can make cancer difficult to study and treat. Cancer's heterogeneity, evident in tumor locations, tumor cell types, subtypes, and microbiota within the tumor microenvironment, complicates diagnosis, prognosis, and treatment. Research into the tumor microenvironment and its microbiota is an evolving area of oncology that may advance cancer drug-patient response. Cancer-omics signatures are crucial to drug response, yet there is no tool that physicians use as a gold standard. Research indicates that microbial presence can alter drug metabolism and immune response, affecting cancer-drug efficacy on a patient-specific basis. This work highlights the need for training readiness in transdisciplinary …


Your Foot Is Not A Brick: Using A Multi-Segment Foot Model To Explore The Actions Of The Ankle-Foot Complex During Uneven Terrain Gait., Tayler Jon Hoekstra Jan 2025

Your Foot Is Not A Brick: Using A Multi-Segment Foot Model To Explore The Actions Of The Ankle-Foot Complex During Uneven Terrain Gait., Tayler Jon Hoekstra

Dissertations and Theses

The field of biomechanics has seen continued development of models to be used and circumstances to be considered. An increasing number of more complex models for the foot known as multi-segment foot models (MSFMs) have created opportunities to better understand the compensatory motion of this vital portion of human anatomy. This research seeks to utilize one such MSFM model to increase understanding in how human ambulation changes in uneven terrain environments. Unique inner-foot joints defined by the Rizzoli foot model (RFM) were measured for and compared for subjects traversing both even and uneven terrain to quantify joints that experienced significant …


Graduate Catalog 2025-2026, Southwestern Oklahoma State University Jan 2025

Graduate Catalog 2025-2026, Southwestern Oklahoma State University

Graduate Catalogs

No abstract provided.


Havana Syndrome: A Scientific Review Of An Unresolved Medical Mystery, Aishik Dutta Jan 2025

Havana Syndrome: A Scientific Review Of An Unresolved Medical Mystery, Aishik Dutta

Digital Journal of Clinical Medicine

Background

Since 2016, U.S. and Canadian officials have reported Anomalous Health Incidents (AHIs), or "Havana Syndrome," characterised by a strange sensory experience followed by chronic neurological, cognitive, and vestibular issues. The cause is intensely debated, with primary hypotheses pointing to either psychosocial factors or a directed-energy weapon, creating a significant medical and geopolitical puzzle.

Methods

This review critically assesses the current evidence by analysing peer-reviewed clinical studies and major institutional reports.

Results

The findings are deeply contradictory. A 2020 NASEM report identified directed, pulsed radiofrequency energy as the most plausible mechanism for a core set of symptoms. Conversely, comprehensive 2024 …


Afit Generative Ai Teaching Guidebook, Afit Faculty Learning Community, Mark G. Bateman, Brett J. Borghetti, Allen W. Dukes, Nicholas C. Francis, Mike Frick, Bobbie Oh, Kevin Patterson, Hiren J. Patel, Mark G. Reith, Erick S. Tyndall, Teresa M. Walton, Torrey J. Wagner, Timothy S. Wolfe, Jonathan Zemmer Jan 2025

Afit Generative Ai Teaching Guidebook, Afit Faculty Learning Community, Mark G. Bateman, Brett J. Borghetti, Allen W. Dukes, Nicholas C. Francis, Mike Frick, Bobbie Oh, Kevin Patterson, Hiren J. Patel, Mark G. Reith, Erick S. Tyndall, Teresa M. Walton, Torrey J. Wagner, Timothy S. Wolfe, Jonathan Zemmer

AFIT Documents

AFIT is proud to highlight the Generative AI Teaching Guidebook, a resource designed to provide military educators with practical insights, strategies, and use cases for integrating Generative AI (Gen AI) into their teaching practices. Developed through a collaborative effort involving AFIT faculty across various departments within the Graduate School of Engineering and Management and the School of Systems and Logistics, this digital resource serves as a starting point for educators exploring how to leverage Gen AI in their classrooms. It offers accessible examples and best practices, ensuring utility for instructors of all technical backgrounds. The guidebook provides a comprehensive overview …


Afit Generative Ai Teaching Guidebook Synopsis, Afit Faculty Learning Community, Mark G. Bateman, Brett J. Borghetti, Allen W. Dukes, Nicholas C. Francis, Mike Frick, Bobbie Oh, Kevin Patterson, Hiren J. Patel, Mark G. Reith, Erick S. Tyndall, Teresa M. Walton, Torrey J. Wagner, Timothy S. Wolfe, Jonathan Zemmer Jan 2025

Afit Generative Ai Teaching Guidebook Synopsis, Afit Faculty Learning Community, Mark G. Bateman, Brett J. Borghetti, Allen W. Dukes, Nicholas C. Francis, Mike Frick, Bobbie Oh, Kevin Patterson, Hiren J. Patel, Mark G. Reith, Erick S. Tyndall, Teresa M. Walton, Torrey J. Wagner, Timothy S. Wolfe, Jonathan Zemmer

AFIT Documents

The main objective of this work was to bring together various perspectives on how to envision incorporating Gen AI capabilities into the learning environment and identify some best practices for their implementation. Any instructor who is interested in these capabilities but does not necessarily have a technical background can find pragmatic use of the examples provided. While the examples have a wide range of applicability, they are meant to serve as a starting point for educators to explore what would be beneficial to their educational environment, from traditional classroom settings to online continuing education courses.


A Comprehensive Exploration Of 6g Wireless Communication Technologies, Md Nurul Absar Siddiky, Muhammad Enayetur Rahman, Md. Shahriar Uzzal, H. M. Dipu Kabir Jan 2025

A Comprehensive Exploration Of 6g Wireless Communication Technologies, Md Nurul Absar Siddiky, Muhammad Enayetur Rahman, Md. Shahriar Uzzal, H. M. Dipu Kabir

Electrical & Computer Engineering Faculty Publications

As the telecommunications landscape braces for the post-5G era, this paper embarks on delineating the foundational pillars and pioneering visions that define the trajectory toward 6G wireless communication systems. Recognizing the insatiable demand for higher data rates, enhanced connectivity, and broader network coverage, we unravel the evolution from the existing 5G infrastructure to the nascent 6G framework, setting the stage for transformative advancements anticipated in the 2030s. Our discourse navigates through the intricate architecture of 6G, highlighting the paradigm shifts toward superconvergence, non-IP-based networking protocols, and information-centric networks, all underpinned by a robust 360-degree cybersecurity and privacy-by-engineering design. Delving into …


Differentiating Opioid Use Disorder From Healthy Controls Via Ml Analysis Of Rs-Fmri Networks, Ahmed Temtam, Megan A. Witherow, Liangsuo Ma, M. Shibly Sadique, F. Gerard Moeller, C. Kenneth, Dianne Wright, Khan M. Iftekharuddin Jan 2025

Differentiating Opioid Use Disorder From Healthy Controls Via Ml Analysis Of Rs-Fmri Networks, Ahmed Temtam, Megan A. Witherow, Liangsuo Ma, M. Shibly Sadique, F. Gerard Moeller, C. Kenneth, Dianne Wright, Khan M. Iftekharuddin

Electrical & Computer Engineering Faculty Publications

Objectives/Goals: This work aims to identify functional brain networks that differentiate opioid use disorder (OUD) subjects from healthy controls (HC) using machine learning (ML) analysis of resting-state fMRI (rs-fMRI). We investigate the default mode network (DMN), salience network (SN), and executive control network (ECN), as well as demographic features. Methods/Study Population: This work uses high-resolution rs-fMRI data from a National Institute on Drug Abuse study (IRB #HM20023630) with 31 OUD and 45 HC subjects. We extract rs-fMRI blood oxygenation level-dependent (BOLD) features from the DMN, SN, and ECN. The Boruta ML algorithm identifies statistically significant features and brain activity mapping …