Digital Commons Network^™

Synergistic Effects Of Hyaluronic Acid And Mechanical Strain On Ovarian Cancer Cell Behaviors, Maranda Erin Kramer

All ETDs from UAB

Ovarian cancer is the most lethal gynecological cancer, but despite this, the effects of the ovarian tumor microenvironment (TME) on disease progression are poorly understood. The TME consist of the extra cellular matrix (ECM), cellular components, and mechanical forces. Cancer associated fibroblasts (CAFs) are stromal cells that secrete several ECM components including collagen, fibronectin, and hyaluronic acid (HA). CAFs also have increased motility and contractility, this increased movement creates micro-strains experienced by the tumor cells in the TME. HA interacts with cancer cells as both a serum and stromal component. Increases in stromal HA in the ovarian TME are associated …

Accuracy Of 3d Printed Models With Various Range Of Crowding Created By Dlp Printer With Different Designs Of Model Base, Chih Yen Liu

All ETDs from UAB

Objective: Treatment planning and appliance fabrication depend on the accurate representation of dentition. Research on the accuracy of digital light processing (DLP) printed models with different base designs across various levels of dental crowding remains limited. This study aims to evaluate the fidelity of DLP printed models and the suitability of different base designs for representing dentition with mild, moderate, and severe crowding. Materials and Methods: The objective is to determine the optimal base designs for DLP-printed models to address varying degrees of dental crowding. A two-way ANOVA was used to compare root mean square (RMS) error across different base …

Evaluating Multiparametric Imaging Biomarkers For Guiding Targeted Therapies In Her2+ Breast Cancer, Ameer Mansur

All ETDs from UAB

Human epidermal growth factor receptor 2 positive (HER2+) breast cancer is a biologically diverse disease, in which intratumoral heterogeneity plays a significant role in tumor progression. Advanced medical imaging and image processing techniques offer the potential to noninvasively characterize the underlying intratumoral biology. Capturing these complex changes can allow for assessing therapeutic response and eventually guiding personalized therapeutic strategies. This work evaluates single and multiparametric imaging biomarkers to characterize tumor biology, identify treatment-induced changes, and predict response to targeted therapies. First, the utility of 3’-Deoxy-3’-[18F]Fluorothymidine positron emission tomography ([18F]FLT-PET) was assessed as a biomarker of proliferation for monitoring response to …

Therapeutic Implications Of Fractionated Radiotherapy And Marcks’ Regulation Of Tunneling Nanotubes In Glioblastoma, Lauren Catherine Nassour-Caswell

All ETDs from UAB

Glioblastoma (GBM) is the most common primary brain malignancy in adults and the gradual development of treatment resistance prevents patients from achieving remission. A primary objective in the field is to devise strategies to overcome this. We predicted this could be achieved by improving existing therapies, creating better models to study GBM, and by identifying a potential therapeutic target. Fractionated radiotherapy (RT) has been used in GBM standard of care for over a century but does not account for GBM heterogeneity. We first hypothesized that in silico mathematical modeling would be a useful tool for cytotoxicity prediction. While this model …

Environmental Exposure To Metals In Children And Their Effects On Autism Spectrum Disorder, Oludesola Ogunesan

All ETDs from UAB

ABSTRACT As scientific understanding of environmental determinants of health advances, growing attention has turned to the role of toxic metal exposures in exacerbating neurodevelopmental outcomes, particularly in vulnerable populations such as children with autism spectrum disorder (ASD). This dissertation investigates the intersection of environmental metal exposure, biomonitoring innovation, and social factors shaping ASD severity in Alabama. Using a multidisciplinary framework, four interrelated studies explore biological, environmental, and participatory dimensions of ASD research and public health. The first study evaluates the utility of Volumetric Absorptive Microsampling (VAMS) for measuring exposure to cadmium (Cd), chromium (Cr), lead (Pb), manganese (Mn), and mercury …

Precast Foundation For Steel Lattice Towers, Wessam Ramadan

All ETDs from UAB

Steel lattice towers are essential structures used in power transmission, telecommunications, and wind turbine towers, where they must withstand various loads to ensure stability and durability. The foundation system plays a crucial role in supporting these towers, with different types chosen based on soil conditions, environmental factors, and project requirements. Traditional foundations, such as drilled shafts, spread footings, and steel grillages have been widely used but often come with challenges, including long installation times, high labor costs, and difficult site conditions. As demand for transmission infrastructure grows, there is a need for faster, more efficient, and environmentally friendly foundation solutions. …

"The Gift Of A Golden Voice": Shaping The Right Of Publicity To Protect Performers From A.I. Abuses, Sebastian Saavedra

Cardozo Arts & Entertainment Law Journal

The note explores the evolving nature of the right of publicity, a unique area of intellectual property and privacy law that protects individuals' control over their likeness and persona. It examines the challenges posed by emerging technologies, particularly AI-generated content, and advocates for a balanced approach that integrates elements from trademark and copyright law while respecting First Amendment rights. The analysis emphasizes the need to protect performers' rights to their public image without undermining established legal frameworks.

Doping Hybrid Photopolymerisable Glass With Bodipy Photosensitiser: An Efficient Approach To Improve Uv-Resistance, Luca Sorridente, Tatsiana Mikulchyk, Metodej Dvoracek, Mikhail A. Filatov, Izabela Naydenova, Kevin P. Murphy

Conference Papers

The development of photosensitive materials with improved performance and extended functionality is crucial for advancing holographic technologies. This study presents the modification and characterization of a recently reported photopolymerisable glass composition, focusing on achieving an optimal balance between maximizing photosensitivity of the material during recording and minimizing the impact of UV light on the performance of the recorded holographic structure. Building on these findings, the ultimate goal is to develop UV-resistant holographic optical elements for wavefront sensing in space applications. The research approach is based on introducing a photosensitiser with weaker UV absorption than the typically used in this material …

Adapting Smart: Rethinking Climate Resilience Through Finance, Security, And Governance, Rafael Leal-Arcas, Tariq Almaniya, Amal Alawdah, Moaz Alshehri, Saad Al-Ruwayshid

Fordham International Law Journal

No abstract provided.

Reducing Transactional Distance With Ai: Examining The Role Of Chatbots In Online Student Satisfaction And Achievement, Joseph Rene Corbeil, Maria Elena Corbeil

Teaching and Learning Faculty Publications

This study explored graduate students’ perceptions of an AI-powered chatbot integrated into an online education course, guided by Moore’s (1997) Theory of Transactional Distance. A total of 47 students completed a survey assessing Dialogue, Structure, Learner Autonomy, Satisfaction, Perceived Achievement, and Intent to Continue Use. Regression analyses revealed that all three transactional distance dimensions significantly predicted student satisfaction, with Dialogue as the strongest predictor. Dialogue and Structure were significant predictors of perceived achievement, while Learner Autonomy significantly predicted students’ intention to use chatbots in future courses. Qualitative responses reinforced these findings, emphasizing the chatbot’s helpfulness and responsiveness. Overall, results suggest …

Trading Places: The Intersection Of Lgbtq Rights And Zionist Rights Under Federal Civil Rights, Marc A. Greendorfer

Touro Law Review

While antidiscrimination laws have a long history at both the federal and state levels, the scope of coverage for these laws has evolved based on nuanced interpretations of terms that previously had established, static meanings. Many antidiscrimination laws prohibit discrimination on the basis of generic categorizations such as sex, religion or ethnicity but such terms are undergoing a rapid change in the way society understands and uses them. For example, sex, which historically has referred to biological gender at birth, now encompasses gender as well as sexual orientation. This article focuses on a recent Supreme Court decision relating to the …

Command And Consequence: Reassessing King David’S Military Decisions In The Uriah Affair – A Legal And Ethical Analysis In The Context Of Modern Legal Theory, Jonathan Hasson, Oded Mudrik, Abraham Tennenbaum

Touro Law Review

This study critically reevaluates King David's command in 2 Samuel 11 and 12 to place Uriah the Hittite in the battle's frontlines, resulting in his death, through the contemporary lens of military law and ethics. By juxtaposing the ancient narrative with modern legal doctrines, it investigates the complexities of command responsibility and the intersection of personal motives in military orders. Focusing on the interplay between David's personal entanglements with Bathsheba and his official capacity as a military leader, the analysis navigates the ethical quandaries and legal ramifications of his decisions. This piece methodically dissects the Biblical text and contemporaneous legal …

Synthesizing Deception: Countering Large Language Model-Generated Phishing Campaigns Through Adaptive Semantic Anomaly Detection, Bekim Fetaji, Debabrata Samanta

Mesopotamian Journal of Computer Science

The paper fills in a gap in the literature that demonstrates an insufficient number of sturdy detection schemes that can recognize the small semantic aberrations inherent in LLM-generated deceptive text. Our proposed co-design hybrid model is Semantic Anomaly Detection with Isolation Forest (SADI) model that combines the synergistic mixture of a fine-tuned transformer-based LLM for deep semantic feature extraction with Isolation Forest algorithm that detects anomalies efficiently. This study introduces SADI, an adaptive semantic-anomaly detector for large-language-model phishing emails. Using a corpus of 10 000 messages, SADI attains an F1 score of 0.981 (95 % CI 0.978–0.984) and processes a …

2025 Retirees Association Newsletter, Morehead State University. Alumni Association.

Morehead State Alumni Association Publications

The Morehead State University 2025 Retirees Association Newsletter.

Perfluorinated Carbon Chain Length Drives Uptake Of Diverse Per- And Polyfluoroalkyl Substances In Field-Deployed Passive Samplers, Matthew Dunn, Jitka Becanova, Simon Vojta, Heidi Pickard, Rainer Lohmann

Graduate School of Oceanography Faculty Publications

Per- and polyfluoroalkyl substances (PFAS) are a group of compounds of high concern due to their ubiquity, persistence, and adverse health impacts. With a diversity of chemical structures and properties, detection tools are needed to capture as many PFAS as possible. In this study, a microporous polyethylene tube (MPT) passive sampler was calibrated for 25 target compounds, 8 suspect PFAS, and extractable organofluorine (EOF) during 1–2 week deployments in groundwater, freshwater river, and estuary contaminated by aqueous film-forming foam (AFFF). Targeted analysis, suspect screening, and EOF were performed on passive and grab samples to derive sampling rates, R_s. …

Bioaccumulation Of Legacy And Novel Pfas In The Environment, Hesham Taher, Rainer Lohmann

Graduate School of Oceanography Faculty Publications

The bioaccumulation of per- and polyfluoroalkyl substances (PFAS), both legacy and novel, in the environment presents significant ecological and health risks. PFAS are a diverse group of synthetic chemicals known for their persistence and bioaccumulation, which can cause widespread environmental contamination and health risks. Strong carbon-fluorine bonds give these compounds unparalleled stability, preventing them from degrading and enabling them to endure in a range of environmental matrices, including water, soil, and biota. Legacy PFAS, including perfluorooctanoic acid (PFOA) and perfluorooctane sulfonic acid (PFOS), have been extensively studied and regulated, resulting in lower concentrations in some environmental media. However, novel PFAS, …

Rebuttal To “Correspondence On ‘Scientists’ Statement On The Chemical Definition Of Pfass”, Gabriel Sigmund, Marta Venier, Marlene Ågerstrand, Ian T. Cousins, Jamie Dewitt, Miriam L. Diamond, Jennifer Field, Alex T. Ford, Shira Joudan, Stefan Van Leeuwen, Rainer Lohmann, Carla Ng, Martin Scheringer, Anna Soehl, Noriyuki Suzuki, Xenia Trier, Sara Valsecchi, Penny Vlahos, Cora J. Young, Zhanyun Wang

Graduate School of Oceanography Faculty Publications

No abstract provided.

Corporate ‘Capture Strategies’ Impacting Human And Ecosystem Health, Alex T. Ford, Marlene Ågerstrand, Michael G. Bertram, Miriam L. Diamond, Rainer Lohmann, Andreas Schäffer, Martin Scheringer, Gabriel Sigmund, Anna Soehl, Maria Clara V.M. Starling, Noriyuki Suzuki, Marta Venier, Penny Vlahos

Graduate School of Oceanography Faculty Publications

The concept of regulatory capture has been extensively studied in academic literature, primarily within the social sciences. This phenomenon has been increasingly discussed in the environmental sciences as the impacts of regulatory capture on human and ecosystem health have become increasingly apparent. Regulatory capture is just one tactic employed by vested interests in the strategy of delaying, weakening, or abolishing policies designed to protect the public interest. Here, we define capture strategies as ‘the act of influencing individuals, organizations, or governments to prioritize corporate interests over those of human and ecosystem health’. Similar to the evolution of terms like whitewashing …

State Of The University Annual Report - 2024-2025, Office Of The President, East Tennessee State University, University Marketing And Communication, East Tennessee State University

Office of the President State of the University Annual Report

No abstract provided.

3d Printing Metal Horn Antennas Using Periodic And Aperiodic Perforated Designs For Directed Energy Applications, Alexis Valencia

Open Access Theses & Dissertations

In the past decade, Additive Manufacturing (AM) has proven to be groundbreaking yet reliable technology. Not only has it revolutionized the way we approach problems in research, design, and production but it has enabled burgeoning discoveries and methods due to the technologyâ??s efficiency, speed, and low manufacturing cost. One area that benefits greatly from this includes radio frequency (RF) devices like horn antennas. At the moment, most horn antennas produced by conventional manufacturing are expensive, heavy, and limited in customization, yet they are necessary for various systems like satellite communication, radar, radio astronomy, and more. 3D printing technology would alleviate …

University Of Minnesota Morris Catalog 2025-2027, University Of Minnesota-Morris

UMM Catalog

This document serves as an official historical record for a specific period in time. The information found is subject to change without notice. Colleges and departments make changes to their degree requirements and course descriptions frequently. More information is available at catalogs.umn.edu.

2025-2026 Craft Academy Student Handbook, Morehead State University. Office Of Communications & Marketing.

Communications and Marketing Publications Archive

The 2025-2026 Craft Academy Student Handbook.

Perceptions Of Influence And Collaboration Amongst Healthcare Providers, Nurses And Allied Health Professionals, Barbara Harrison

Dissertations

Problem

While attention to interprofessional collaboration is increasingly present in academic settings and in clinical practice, there is little understanding of the role power, specifically the scope of influence, plays in interprofessional collaboration.

Method

Targeted cross-sectional sampling was used to select possible candidates to participate in this quantitative study. An email invitation was sent to healthcare providers, nurses and allied healthcare professionals in a multi-hospital healthcare system in the mid-western United States of America. Willing participants proceeded to the Microsoft Forms survey via an embedded link which was available to them for eight days. The survey sought demographic information, and …

Navigating Big Data In Cyber Archaeology: An Updated Four-Field Approach Applied To San Miceli, Jared Wilson

Dissertations

Problem

This dissertation examines the evolving role of digital technologies in archaeological research, focusing on the management and interpretation of extensive digital datasets generated by modern excavations. Drawing on six years of comprehensive fieldwork at San Miceli, Sicily, this study critically evaluates and updates the established four-field methodology proposed by Levy et al. (2012), encompassing acquisition, analysis, dissemination, and curation. While traditional archaeological documentation methods rely heavily on analog techniques, these approaches increasingly fall short due to the rapid expansion and complexity of digital data.

Method

To address this gap, the dissertation refines and expands the current methodological framework by …

2025 Conference Program, Georgia Southern University

SoTL Commons Conference

2025 Conference Program

Enhancing Electric Vehicle Security And Privacy Through Decentralized Identity Management, Abdullah Aydeger, Engin Zeydan, Josep Mangues-Bafalluy, Suayb S. Arslan, Turk Yekta

Electrical Engineering and Computer Science Faculty Publications

In the next decade, Electric Vehicles (EVs) are expected to contribute to reducing climate change and transforming road mobility significantly. However, the security and privacy of EV charging systems pose considerable challenges that need to be addressed. This article introduces a novel approach by integrating blockchain-based Self-Sovereign Identity (SSI) to enhance the security and privacy of EV charging systems. By leveraging the decentralized and immutable nature of blockchain, the proposed SSI framework can ensure secure and private data exchanges between EVs, charging stations, and backend systems. This three-way integration addresses the vulnerabilities identified in existing EV charging methods, such as …

Modelling The Hydrologic Impact Of Land Cover On Stormwater Detention Basins In Harris County, Tx, Kabita Sapkota

Electronic Theses and Dissertations

Harris County on the upper Gulf Coast in Southeast Texas is susceptible to both riverine and coastal flooding due to intense, short-duration thunderstorms, slow-moving frontal systems, and tropical hurricanes. Low-lying terrain, clay soils with poor drainage, high annual rainfall, and a widespread network of bayous and streams all contribute to frequent flooding. To reduce the impacts of urbanization and the loss of surface storage, the Harris County Flood Control District (HCFCD) built detention basins throughout the county to temporarily store stormwater runoff and release it slowly, lowering peak flows and preventing downstream flooding and erosion. These basins vary in land …

A Quality Improvement Project Reinforcing Nursing Education On Support Resources For Families In The Icu, Emily Siel

Master's Theses and Capstones

BACKGROUND: The Intensive Care Unit (ICU) is often a source of psychological, physical, social, financial, and spiritual distress for families of patients. Multidisciplinary support resources are available but are often underutilized. Nurses are uniquely positioned to assess needs and integrate resources into care. Therefore, enhancing nurses' ability to guide families to appropriate support resources may alleviate distress and promote holistic well-being for patients and their families.

METHODS: The Plan-Do-Study-Act (PDSA) model was used to guide this project. A pre-intervention survey assessed awareness, utilization, and perception of ownership. Following dissemination of the intervention, a post-survey evaluated improvements in knowledge and integration. …

Global Tax Wars In The Digital Era, Assaf Harpaz

Scholarly Works

The digital economy fundamentally disrupts international tax principles that rely on physical presence. When a business earns income abroad, the country of residence (where the taxpayer resides) and the country of source (where income is generated) both have legitimate, competing claims to tax that income. The international tax system tends to favor residence-based taxation. The source country has the right to tax business profits only if the enterprise carries on a permanent establishment within its borders, which typically requires physical presence. The permanent establishment standard becomes flawed in a digital economy where profit shifting practices are abundant and businesses no …

Cliff Running, William Ortman, Dov Fox

Scholarly Works

Professionals must at times make snap judgments that have profound consequences. Does a doctor perform an otherwise forbidden abortion to preserve a patient’s failing health? Does a police officer fire at a suspect pointing an unidentified metal object? The criminal law tells these professionals: Don’t intervene unless the danger is serious and the risk is imminent. But it offers little to guide that determination beyond: Be reasonable. Yet the “right” choice—the one that’s legally safe—often resembles the “wrong” one: a felony punishable by decades in prison. These ambiguous regimes operate as liability cliffs that professionals are forced to traverse at …