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Studies To Delineate The Structure And Function Of The Human Ventricular Myocardium In Subjects With Type-Ii Diabetic Cardiomyopathy, Haritha Keerthi

Open Access Theses & Dissertations

Heart failure, an abnormal heartbeat, and sudden death are all possible outcomes of preexisting or underlying cardiac disease. Heart disease is highly correlated with diabetes, causing heart pain and shortness of breath. In patients without other cardiac conditions, diabetic cardiomyopathy is a process that affects the myocardium over a long period of time. This disease has a complicated pathophysiology that can be broken down into processes that lead to diastolic and/or systolic dysfunction. However, the pathophysiological differences between normal, diabetic, and diseased cardiac tissues have not been thoroughly studied. Therefore, in this research, we directed our efforts to perform a …

Inference Per Joule: A Performance Metric For Artificial Intelligence In Space Applications, Eduardo Macias Zugasti

Open Access Theses & Dissertations

The use of artificial intelligence (AI) has grown exponentially in recent years. This growth is driven in part by the significant advancements in computing capabilities, which have also increased exponentially. Computers have not only become more powerful but also smaller in size, thanks to the evolution of transistor technology. These developments have enabled AI to become a widely accessible tool, even in recreational activities such as image creation and entertainment videos.

More recently, the use of AI has extended to space applications, where it can enhance and optimize various tasks. However, space conditions pose significant challenges for conventional computers due …

Computing Optimal Progressive Hybrid Censoring Schmes Using An Mcmc Type Probabilistic Approach, Irene Yemotiorkor Odoi

Open Access Theses & Dissertations

Progressive hybrid censoring schemes play a crucial role in optimizing life-testing experiments by balancing test duration and statistical efficiency. This study presents a Markov Chain Monte Carlo (MCMC)-based probabilistic approach for determining optimal progressive hybrid censoring schemes, incorporating a time-dependent component that enhances traditional progressive censoring methods.We implement our approach using three distinct probability distributions the multinomial, hypergeometric, and uniform distributions to simulate censoring schemes. The optimal censoring schemes are then identified based on three optimality criteria: A-optimality, D-optimality, and T-optimality, ensuring robust selection by minimizing estimator variance, maximizing Fisher information, and optimizing test duration, respectively..To evaluate the effectiveness of …

Exploring Willingness To Seek Help And Well-Being In Rural Veterans With Health Conditions: A National Rural Health Study, Jimena Isabel Ortiz

Open Access Theses & Dissertations

The population of Veterans in the United States has increased significantly, with a substantial number residing in rural areas. This study aims to highlight and understand the correlation between military service members' physical and mental well-being and the quality/access to care they receive. This study also aims to explore mental health-seeking behaviors, health, and well-being in rural Veterans with health conditions. The study included 400 rural-dwelling Veterans with documented physical and mental health conditions. Data was collected through surveys distributed via various media channels, including social media platforms, and the results demonstrated that willingness to seek psychological help was positively …

From Land To Lagoon: The Spatiotemporal Biogeochemical Dynamics Of Arctic Coastal Erosion In Elson Lagoon, Alaska, Sasha Victoria Peterson

Open Access Theses & Dissertations

TThe Arctic is warming rapidly, driving widespread environmental change across coastal landscapes, including permafrost thaw, shoreline erosion, and shifts in sediment and carbon dynamics, pose growing challenges for predicting carbon cycling and climate feedbacks. This dissertation investigates the spatiotemporal variability of erosion, decomposition, and nearshore turbidity in Elson Lagoon, Alaska (1955–2023), to better understand how carbon, nitrogen, and sediment are mobilized, transformed, and potentially emitted as greenhouse gases in Arctic coastal systems. Chapter 2 presents a high-resolution analysis of shoreline change and erosion-driven material fluxes spanning nearly seven decades. Drawing on 795 soil data points, airborne LiDAR, and five shoreline …

Improving Traffic Management During Special Events At The Sun Bowl Stadium, Marek Polak

Open Access Theses & Dissertations

This thesis focuses on improving traffic conditions around the Sun Bowl Stadium, especially during large public events. The goal is to propose effective solutions that enhance the use of public infrastructure during both event days and normal traffic conditions. To understand the current situation, two surveys were conducted during a football game - one monitoring parking lot occupancy and the other measuring traffic volumes using video recordings and pressure sensors. Based on the collected data, design changes were proposed for two key intersections: Sun Bowl Dr. with W. University Ave., and Sun Bowl Dr. with Glory Rd. The new designs …

Fibrin-Polycaprolactone Scaffolds For The Differentiation Of Human Neural Progenitor Cells Into Dopaminergic Neurons, Salma Paulina Ramirez

Open Access Theses & Dissertations

This project aimed to develop a tissue-on-a-chip platform for studying Parkinson's Disease (PD) using dopaminergic (DA) neurons. PD is a neurodegenerative disorder characterized by progressive loss of DA neurons, leading to involuntary movements and other symptoms. Early diagnosis and deeper understanding of PD pathogenesis are crucial for improving disease management and patient outcomes. To model PD in vitro, this research utilized human-induced pluripotent stem cell (hiPSC)-derived neural progenitor cells (NPCs) cultured on electrospun (ES) polycaprolactone (PCL) scaffolds. Given PCL's hydrophobicity, ECM-based biomaterial coatings, including Cell Basement Membrane (CBM) proteins, Matrigel, and Fibrin, were explored to enhance NPC adhesion, differentiation, and …

Enhancing Security And Resiliency In Operational Technology Environments Through Network Slicing And Federated Learning, Brian Giovanni Rodiles Delgado

Open Access Theses & Dissertations

The growing convergence of Information Technology (IT) and Operational Technology (OT) within Industry 4.0 environments has introduced new demands on industrial network infrastructure. As cyber-physical systems become increasingly interconnected, ensuring the secure, timely, and efficient exchange of critical data is essential. This thesis explores how network slicing, a method of creating isolated virtual network segments, can be applied within OT environments to address challenges such as latency, security, and resource allocation.

The first research question addressed in this thesis is: How can OT networks take advantage of NFV and SDN technology to become cyber resilient? This study examines the operational, …

H.O.V. - A Novel, David Christopher Rout

Open Access Theses & Dissertations

In this novel. An agribusiness executive from Toronto lives as a homeless man in 1990's Los Angeles. He's wanted for a crime in Canada and is unable to find conventional work. His living involves being a professional passenger for morning and afternoon commuters who wish to use the High Occupancy Vehicle lane. After falling in love with a clerk at a used paperback store, he must confront his choices and deal with the circumstances of his wife's death.

Machine Learning And Protein Engineering Approaches To Understanding Kinesin-5 Activity, Jason Eden Sanchez

Open Access Theses & Dissertations

Cancer is a term describing a collection of diseases that result in uncontrolled cell growth. Cancer has manifold etiologies and underlying cancers are rouge biochemical pathways involving many different proteins. In the current work, two approaches are used to enhance knowledge of kinesin-5, a potential cancer target involved in cell division. Kinesin-5 promotes cell division by cross-linking and separating microtubules in dividing cells. The first approach uses machine learning (ML) to identify small molecule inhibitors for kinesin-5. Though decades of research have uncovered classes of small-molecules which inhibit kinesin-5 in vitro and in vivo, no candidates have reached phase III …

Engineering Of Metallic Interpenetrating Phase Composites For The Control Of Deformation And Failure Modes During Dynamic Events, David Kiyoshi Santacruz

Open Access Theses & Dissertations

Aerospace components, automotive structures, and ballistics armor are all engineered to withstand high strain rate service events through a combination of material selection and design choices. However, structural components may be less effective when their implementation is constrained by other factors such as weight or design limitations. To meet these challenges, the development of next-generation materials will need to increasingly rely on composite material systems rather than monolithic materials. This thesis presents the fabrication, dynamic characterization testing, and post-mortem analysis of 316L/A356 interpenetrating phase composites (IPCs) made from the PrintCasting methodology. These composites consist of additively manufactured 316L stainless steel …

"Until There Is Nothing Left:" The Environmental And Social Impact Of Extractivist Industries In Grant County, New Mexico 1852-1999, Benjamin Shultz

Open Access Theses & Dissertations

This dissertation research expands and deepens our understanding of the environmental and social impact of the extractivist industries in Grant County, New Mexico, from 1852 to 1999. Much of the scholarship around mining in the historiography tends to focus on Arizona and Northern New Mexico, given the centralization of the mining industry in places like Taos and Santa Fe. The impact of the mining industry on the unique ecosystem and people who resided in Grant County, New Mexico, has not been as thoroughly researched by scholars. Thus, this dissertation extends the literature by revealing how the extractivist industries permanently changed …

"Alone I Can't, But Together We Can": A Photovoice Study To Explore Insights Of Assisted Outpatient Treatment (Aot) From Providers Working With Individuals With Serious Mental Illness (Smi)., Monica G. Urquieta

Open Access Theses & Dissertations

Assisted Outpatient Treatment (AOT) is a court-ordered mental health treatment program for individuals with SMI (bipolar disorder, major depressive disorder and schizophrenia) who have a history of noncompliance with treatment and are at risk of deteriorating or causing harm to themselves or others. This dissertation examined the perceptions and experiences of thirteen providers (lawyers, judges, case managers, psychiatrists, housing navigators, treatment guardians, nurse practitioners, therapists and peer support specialists with lived experience) on the AOT program for clients with SMI; and the environments that shape these perceptions, taking into account a system and community-based approach focusing on how the unique …

A Sociocognitive Perspective On The Activation Of Productive Epistemic Resources In College Students' Understanding Of Chemical Equilibrium, Henk Steven Van Den Bogaard

Open Access Theses & Dissertations

Science education, particularly in higher education, has a content coverage problem: it has long been described as "a mile wide, an inch deep" in various consensus documents from the National Academies. In chemistry education, the most common general chemistry curriculum covers topics as chapters based on the popular Sienko and Plane 1960's general chemistry textbook. The limited time available in such fast-paced coverage may limit the instructor's modeling and assessment of key performances in developing a mechanistic understanding of complex chemistry phenomena. In this sociocognitive, qualitative investigation, general chemistry II students' responses to assessment prompts were used to activate cognitive …

Feasibility Of On-Demand Charging For Private Evs At The El Paso International Airport, Katerina Zizalova

Open Access Theses & Dissertations

As electric vehicle adoption rate continues to grow globally and across the United States, it is desirable for airports to adapt to meet the needs of electric vehicle driving passengers. This thesis develops an implementation plan for an on-demand charging solution for the El Paso International Airport to address the current limitations in charging infrastructure. After analyzing the electric vehicle adoption trends, four charging solutions were studied: conventional fixed-point charging, fixed-point charging with added valet service, mobile charging service and wireless inductive charging. Using decision-making matrices implementing criteria such as operational suitability, scalability or costs, one charging solution was recommended …

Application Of Deep Learning On Gage R&R For Anomaly Detection, Oluwatope Richard Ojo

Electronic Theses and Dissertations

This thesis explores the application of deep learning techniques, specifically autoencoder based models, to enhance anomaly detection within Gage Repeatability and Reproducibility (Gage R&R) studies—an essential component of Measurement System Analysis (MSA) in quality engineering. Traditional Gage R&R methodologies, while effective for linear and low-dimensional data, exhibit limitations in detecting subtle, nonlinear variations in complex measurement systems. To address this challenge, an unsupervised autoencoder was developed and trained on a synthetically generated dataset comprising 2,500 voltage measurements (5V and 33V) derived using Generative Adversarial Networks (GANs) based on real-world manufacturing data measurements.

The proposed autoencoder model achieved a 95th percentile-based …

Tracing Wave Induced Flow Field Surrounding Reef Balls, Alexis Scheele

Theses and Dissertations

This study aims to explore the wave-induced flow dynamics around Reef Ball models using dye tracing techniques. Reef Balls are hemispherical artificial reefs with a hollow center and cavities throughout each face, they are designed in this manner to enhance coral reef restoration. Reef Balls rely on wave energy and current motion to facilitate water circulation and nutrient exchange within and surrounding their structure. To understand how wave action influences flow patterns around these artificial reefs, a scaled model experiment was designed to simulate real-world conditions. The experiments were conducted in the wave flume at Florida Institute of Technology’s Surf …

Implementation Of Unscented Kalman Filter-Based State Estimation For Multiple Spacecraft Using Global Positioning System Measurements, Bala Prenith Reddy Gopu

Theses and Dissertations

This study presents an implementation of state estimation for a drag-based rendezvous mission involving multiple chaser spacecraft and a single target, using Unscented Kalman Filtering (UKF) with Global Positioning System (GPS) measurements. The implemented method combines GPS navigation solutions with UKF to provide real- time state estimates of all spacecraft involved. Nonlinear least squares method is employed to process pseudorange and pseudorange rate measurements to determine receiver states, UKF utilizes these states as measurements to estimate absolute space- craft positions and velocities. This implementation also addresses practical challenges including raw GPS measurement processing, and varying GPS satellite geometries.

C-Band Air To Ground Communication System For Uav, Mubark Alghamdi

Theses and Dissertations

C band spectrum 5030-5091 MHz is allocated for command-and-control communication services with unmanned aircraft systems. This document evaluates the possibility of using 3GPP 5G standards for provisioning of such services. Channelization of the spectrum and major system parameters are proposed. The performance of the proposed system in channel fading environment is evaluated using MATLAB based simulations. The evaluations examine SINR, and average throughput of the proposed system at different altitudes of the unmanned aircraft system. MATLAB simulations are used to evaluate system performance in free-space environments. Signal-to-Interference-plus-Noise Ratio (SINR) and Reference Signal Received Power (RSRP) are predicted at different UAS …

The Impact Of System Transparency On Perceived System Reliability, Perceived System Usability, And Information Clarity In Self-Driving Car Systems, Uditkumar Nair

Theses and Dissertations

In human-computer interaction (HCI), the development of autonomous vehicle (AV) technology has created new difficulties, especially in building user confidence as well as understanding of system functioning. The effect of system transparency on user- centered outcomes, such as perceived usability, perceived system reliability, and information clarity, is examined in this thesis. In order to evaluate their experiences in both ordinary and high-stakes driving situations, participants engaged with both system- transparent user interfaces (TUIs) and non-transparent user interfaces (NTUIs) across a number of experimental scenarios. In order to assess how well each interface conveyed system logic and actions, the study included …

Developing End-To-End Imitation Learning For Asteroid Proximity Operations, Patrick David Quinn

Theses and Dissertations

Asteroid exploration remains a popular topic in the scientific community, however hurdles still exist for controlling spacecraft within the asteroid environment. Communication delays often require the usage of limited onboard computing hardware for navigation. Additionally, long mission timelines must be accommodated with highly efficient fuel use. Considering these issues, it is apparent that any guidance, navigation, and control (GNC) system in these spacecraft should emphasize both computational and fuel efficiency in its design. Furthermore, the integration of a robust state estimation system is necessary for the successful deployment of such systems. The development of a controller aiming to address these …

Patterns Of Fire History And Vegetation Changes In The Last 5000 Years: A Paleoecological Study Of Iquitos, Annabel Zwarts

Theses and Dissertations

The vegetation of the Amazonian rainforest is hypothesized to have been shaped by pre-Columbian activities, such as burning and palm management to various extents. Management of palms is hypothesized to have caused some of the most useful species to become hyperdominant in Amazonia. This study investigated the extent to which human activities over the past 5000 years affected palm abundances in mature lowland rainforests near Iquitos, Peru. I used phytoliths and charcoal from soil cores to determine the history of local floras, and modern palm surveys to compare modern phytolith occurrence with modern vegetation. Because pre-Columbian activity clustered along the …

Towards Visual Inertial Navigation With Fixed Tetrahedral Targets, Joao Leonardo Silva Cotta

Theses and Dissertations

This dissertation presents a robust method for 6DoF position estimation under impaired visual conditions utilizing a minimum 4-point Perspective-n-Point (P4P) solver designed for tetrahedral targets. Using SO(3) × R 3 instead of SE(3), the method uses a Lie group-based formulation to discriminate between rotation and translation, thereby enabling computationally efficient, resource-conscious op- optimization while preserving correct geometric behavior. Designed using the contemporary C++17 library ShomerTarget, the solver is analytically formulated and assessed under pragmatic robotic conditions. Particularly in low-light and high-dynamic environments, experiments on embedded systems, UAVs, and NASA’s Astrobee show that the proposed solver attains enhanced accuracy compared to …

Mixed-Mode Fracture Analysis Of Additively Manufactured Periodic Orthotropic Functionally Graded Microcellular Materials, Behnam Shahbazian

Theses and Dissertations

The quest for safety, efficiency, and innovation in aerospace engineering demands a relentless focus on understanding how materials and structures behave under extreme and complicated loading conditions. Among the many challenges faced by engineers in this field, predicting and preventing structural failure stands out as both a fundamental necessity and a complex problem. Fracture mechanics, the science of how materials fail under stress, is a cornerstone of this effort. Whether it is the fuselage of an aircraft enduring cyclic loading or the lightweight components of a spacecraft resisting impact, the ability to accurately predict fracture behavior directly influences the reliability …

Experimental And Theoretical Fracture Analysis Of Rift Manufactured Carbon Fiber-Vinyl Ester Lamina, Daniel Joseph Longo

Theses and Dissertations

This thesis investigates the fracture behavior of unidirectional carbon fiber-vinyl ester (CFVE) laminates manufactured using the Resin Infusion with Flexible Tooling (RIFT) process, a cost-effective alternative to autoclave-based fabrication methods. Composite materials like CFVE are increasingly adopted in high-performance applications due to their high strength-to-weight ratio and corrosion resistance; however, their anisotropic nature presents challenges in predicting crack initiation and propagation. To address this, a comprehensive approach combining experimental testing, finite element modeling (FEM), and classical fracture mechanics was employed. Orthotropic mechanical properties were first determined through tensile and shear tests, providing critical properties for FEM simulations. A series of …

Use Of Pushed-In Pencel Pressuremeter Test For Shallow Foundation Design In Florida Fine Sands, Brhane Weldeanenya Ygzaw

Theses and Dissertations

A comprehensive evaluation was conducted on the performance, consistency, and practical application of various in-situ geotechnical testing methods for predicting the settlement and bearing capacity of shallow foundations in Florida’s fine sands. The methods assessed include the Standard Penetration Test (SPT), Cone Penetration Test (CPT), Dilatometer Test (DMT), pushed-in PENCEL Pressuremeter Test (PPMT), and the pre-bored TEXAM Pressuremeter Test. A dual approach controlled indoor testing at the FDOT State Materials Office (SMO) and field investigations at three representative sites (Kingsley, Trenton, and the UCF research site), formed the experimental foundation.

Over thirty settlement prediction techniques and thirteen bearing capacity estimation …

Effects Of Reflective Journaling And Nudges On Academic Motivation And Engagement, Lakshmi Satya Sai Veda Mahita Uppuluri

Theses and Dissertations

This study investigates the effects of reflective journaling and motivational nudges on academic motivation and engagement among college students. Grounded in Self- Determination Theory (SDT), the research examines how different interventions influence intrinsic motivation, and academic behaviors such as class attendance, participation, and preparation. The study employed a between-group experimental design with three conditions: a control group, a journaling group, and a journaling group that also received daily motivational nudges. Results showed that students in the journaling groups—particularly those who received nudges—experienced a significant increase in academic motivation. While changes in academic engagement were not significant, the effect size suggested …

Stochastic Analysis With Operational Calculus In Reliability, Hend Hamdan Al-Jahani

Theses and Dissertations

Our dissertation models several reliability systems subject to occasional random shocks of random magnitudes W1,W2,..occurring at times tau0, tau2,..In Model 1, the underlying system becomes inoperational if it wears out due to aging specified by a monotone increasing continuous function Delta identifying system's wear at any time t>=0 . The system is deemed inoperational if delta crosses a sustainability threshold at some moment T=(delta )^-1(D). The precise time T is difficult to identify making the realistic failure time randomly delayed and thus identified at some opportune observation epoch. The system can also fail due to damages by external shocks, …

The Prototype Of A Fully Automated Pressuremeter For Various Geotechnical Applications, Anuar Akchurin

Theses and Dissertations

The geotechnical engineering field requires high-quality in-situ testing equipment that ensures consistency in the test execution. This research focuses on developing and testing a prototype of a fully automated pressuremeter control unit to allow the industry to obtain reliable and controlled stress-strain data, thereby improving efficiency and reducing testing time.

The objectives of this work are to design and develop a system with the necessary components to perform the pressuremeter test, integrate the testing procedure into the state machine design, enable automated testing, and validate the results by comparing the stress-strain data with that obtained from the existing hand-operated pressuremeter …

Alternative Robust Design Formulation And Exploration Strategies For Managing Uncertainties In The Realization Of Complex Engineering Systems, Pooja Mukundan

Theses and Dissertations

The design of complex engineered systems often relies on simulation-based models, which inherently introduce uncertainties. Managing these uncertainties is critical to ensure robust system performance. From a decision-based design (DBD) perspective, robust design metrics such as the Design Capability Index (DCI) and Error Margin Index (EMI) are employed to formulate and solve problems under uncertainty. However, existing formulations of these metrics rely on first-order Taylor series approximations for variance estimation, which are often inadequate in the presence of highly nonlinear or multimodal performance functions.

This thesis proposes alternate formulations of DCI and EMI, which use the multiple-point method of variance …