Digital Commons Network^™

Nsf Eec: Establishing Utrgv’S Center For Broadening Participation In Engineering: Engage, Educate, Enrich, Ala Qubbaj, Laura Benitez, Noe Vargas Hernandez, Constantine Tarawneh, Arturo A. Fuentes, Nazmul Islam, Edna Orozco-Leonhardt, Thuy Vu, Angela M. Chapman

Mechanical Engineering Faculty Publications

Hispanics are one of the fastest growing populations in the US, yet they are underrepresented in engineering. University of Texas Rio Grande Valley (UTRGV), a major Hispanic Serving Institution (HSI) with a student population over 95% Hispanic, is well-positioned to address this disparity. UTRGV established a Center for Broadening Participation in Engineering: Engage, Educate, Enrich (CBPE-E3) to enhance Hispanic participation in engineering from early awareness through professional employment. The CBPE -E3 aims to increase enrollment, retention, and advancement rates of Hispanic students in higher education engineering, especially Latinas facing intersectional barriers of race and gender. The CBPE -E3 envisions becoming …

Multi-Point And Multi-Station Orbit Propagation For Non-Functional Drifting Geo Satellites, Hritik Mitra

Theses

Currently, there are thousands of man-made space objects that are orbiting the Earth. These satellites serve a host of essential purposes (scientific research, technical applications, services) and they are all required to remain within their mission parameters. Most critical for them is to maintain the orbital parameters that are specified to achieve a particular mission’s objectives. If a satellite deviates beyond a certain limit, there is not only a risk of mission failure but there is a major hazard for possible collisions with other objects such as active satellites, space debris and even natural objects in some cases. There is …

Investigation And Prediction Of Excessive Water Production In Bottom Water-Drive Naturally Fractured Reservoirs Using Machine And Deep Learning, Sami Abderraouf Belkhir

Theses

Naturally Fractured Reservoirs (NFRs) are characterized by dual-porosity and dual-permeability systems, posing significant challenges in managing water production due to highly conductive fracture networks that facilitate rapid water migration from bottom aquifers, often bypassing oil stored in the matrix, thus resulting in early water breakthrough and water channeling phenomena. The main objective of this thesis is to develop and validate deep learning and machine learning models to predict water production, water breakthrough time (tbt), and ultimate water cut (WCult) in NFRs, thereby enabling more effective reservoir management strategies. This work also aims to evaluate the sensitivity of water behavior to …

Data-Driven Machine Learning Applications For Predictive Modeling Of Petrochemical And Ecofriendly Systems, Noora Saleh Al Mansoori

Theses

Traditional experimental approaches in industrial processes, such as Fourier Transform Infrared Spectroscopy (FTIR) spectroscopy, thermogravimetric analysis (TGA), and well-drilling operations, are often constrained by time, cost, and operational limitations. This research explores the application of data-driven Machine Learning (ML)-based predictive modeling to improve efficiency and reduce dependency on resource-intensive experimentation. The study develops ML models for three distinct processes: FTIR intensity prediction of bitumen thermal cracking products, thermal degradation of Medium-Density Fibreboard (MDF) using TGA data, and Rate of Penetration (ROP) prediction in petrochemical industry. Six algorithms: Linear Regression (LinReg), Partial Least Squares Regression (PLSR), Support Vector Regression (SVR), Gradient …

Wavelet-Based Multi-Step Methods For Systems Of Differential Equations, Rashad Assad Hijji

Theses

Wavelets have been widely used in many areas of engineering and mathematics, including the development of multistep algorithms to solve initial value problems (IVPs) in the context of the Galerkin method using Daubechies' wavelets. The main scope of our work is to build a comprehensive framework for solving Systems of Differential equations using the compactly supported wavelets proposed by I. Daubechies. Wavelets are mathematical functions that decompose data into distinct frequency components, and each element is analyzed with a resolution that matches its scale. Compact support of Daubechies wavelets is key in allowing them to be computationally efficient for high-dimensional …

Electrospun Membranes From Bio-Renewable Poly (Ethylene Furanoate)/Poly (Ethylene Teraphthalate) (Pef/Pet) Blend For Emulsification Application, Aya Ismat Sayed

Theses

This thesis focuses on manufacturing electrospun fibrous membranes from a blend of poly (ethylene terephthalate) and poly (ethylene furanoate) and using in premix emulsification. Poly (ethylene furanoate), which is a 100% bio-renewable polymer being blended with synthetic poly (ethylene terephthalate) for membrane fabrication contributes towards sustainability in the production of food and pharmaceutical emulsions. The primary objective of this research is to optimize the fabrication conditions of poly (ethylene terephthalate)/poly (ethylene furanoate) porous membranes, characterize their properties, and evaluate their performance in emulsification. This study compares poly (ethylene terephthalate) / poly (ethylene furanoate) blend membranes with individual poly (ethylene terephthalate) …

Experimental And Computational Study Of Slow Crack Growth Of High Density Polyethylene, Abdulla Fawzi Almomani

Dissertations

This dissertation investigates the slow crack growth (SCG) behavior of High-Density Polyethylene (HDPE) under various mechanical and environmental conditions. The study combines experimental analysis and computational modeling to enhance the understanding of SCG mechanisms in HDPE, particularly in pressurized pipes and under the exposure to hydrocarbons. A novel Crack Layer (CL) theory-based SCG model is developed and validated through experimental data, offering a predictive framework for HDPE failure assessment. The main objective of this dissertation is to quantify and model the viscoelastic-viscoplastic behavior of HDPE under monotonic and cyclic loading conditions while addressing SCG kinetics in structural applications. The study …

Utilizing Date Fruit Pomace As A Corrosion Green Inhibitor For Non Ferrous Alloys, Sardor Rustam Odilov

Theses

This thesis explores a novel green corrosion inhibitor derived from date fruit pomace extract (DFPE) for the protection of aluminum alloy 3003 in highly corrosive environments, specifically hydrochloric acid (HCl) and natural seawater. The central aim is to promote the sustainable reuse of agro-waste as an effective and eco-friendly alternative to conventional toxic inhibitors, aligning with environmental and industrial safety goals.

A comprehensive methodology was employed, including Soxhlet extraction (using both non-polar n-hexane and polar methanol-water solvents), rotary evaporation, and FTIR analysis to identify the active functional groups responsible for inhibition. Corrosion behavior was systematically evaluated using both mechanical (weight …

Comparative Genotoxicological Analysis Of Occupational Pesticide Exposures: An Experimental Approach And Systematic Review, Moustafa Samy Sherif

Dissertations

This dissertation investigates the genotoxic and cytotoxic effects of pesticide exposure through three complementary research components: a systematic review of occupational pesticide exposure in Arab countries (AraSys), a systematic review on encapsulated versus conventional pesticide formulations (Encap-Sys), and experimental toxicological assessments of various pesticide formulations in human cell lines (Pyr-Ex). This experimental component includes cytotoxicity assays using propidium iodide and DNA damage assessments via alkaline comet assays in HL60 and HepG2 cell lines exposed to pyrethroid insecticides and glyphosate-based formulations.

The AraSys systematic review revealed a critical positive association between occupational pesticide exposure and DNA damage in agricultural workers in …

On-Site Water Management Field Sampling Plan (Fsp), 2025 Update, Mark Thompson, Rampart Solutions

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Meta-Learning Hyperparameters For Foundation Model Adaptation In Remote-Sensing Imagery, Zichen Tian, Yaoyao Liu, Qianru Sun

Research Collection School Of Computing and Information Systems

Training large foundation models of remote-sensing (RS) images is almost impossible due to the limited and long-tailed data problems. Fine-tuning natural image pre-trained models on RS images is a straightforward solution. To reduce computational costs and improve performance on tail classes, existing methods apply parameter-efficient fine-tuning (PEFT) techniques, such as LoRA and AdaptFormer. However, we observe that fixed hyperparameters -- such as intra-layer positions, layer depth, and scaling factors, can considerably hinder PEFT performance, as fine-tuning on RS images proves highly sensitive to these settings. To address this, we propose MetaPEFT, a method incorporating adaptive scalers that dynamically adjust module …

Dupin: A Parallel Framework For Densest Subgraph Discovery In Fraud Detection On Massive Graphs, Jiaxin Jiang, Siyuan Yao, Yuchen Li, Qiange Wang, Bingsheng He, Min Chen

Research Collection School Of Computing and Information Systems

Detecting fraudulent activities in financial and e-commerce transaction networks is crucial. One effective method for this is Densest Subgraph Discovery (DSD). However, deploying DSD methods in production systems faces substantial scalability challenges due to the predominantly sequential nature of existing methods, which impedes their ability to handle large-scale transaction networks and results in significant detection delays. To address these challenges, we introduce Dupin, a novel parallel processing framework designed for efficient DSD processing in billion-scale graphs. Dupin is powered by a processing engine that exploits the unique properties of the peeling process, with theoretical guarantees on detection quality and efficiency. …

Large Language Model For Vulnerability Detection And Repair: Literature Review And The Road Ahead, Xin Zhou, Sicong Cao, Xiaobing Sun, David Lo

Research Collection School Of Computing and Information Systems

The significant advancements in Large Language Models (LLMs) have resulted in their widespread adoption across various tasks within Software Engineering (SE), including vulnerability detection and repair. Numerous studies have investigated the application of LLMs to enhance vulnerability detection and repair tasks. Despite the increasing research interest, there is currently no existing survey that focuses on the utilization of LLMs for vulnerability detection and repair. In this paper, we aim to bridge this gap by offering a systematic literature review of approaches aimed at improving vulnerability detection and repair through the utilization of LLMs. The review encompasses research work from leading …

The Right Answer For The Wrong Reason: Preservice Science And Mathematics Teacher Preferences And Explanations Of Inquiry-Based Teaching, Elizabeth R. Goldberg, Taylor K. Darwin

School of Integrative Biological & Chemical Sciences Faculty Publications

Inquiry in science and mathematics education has a long and established history within the student-centered teaching movement because it can positively impact student learning, retention, and engagement. Yet few teachers have embraced these practices in the classroom. Potential reasons include misalignment of teachers’ attitudes about inquiry and a lack of understanding of what inquiry is and how to implement it in the classroom. This mixed-methods study compares these claims by examining preservice teachers’ attitudes and knowledge about inquiry-based teaching. Eighty-seven discussion posts were analyzed on preservice science and math teachers’ preferences for inquiry-based versus teacher-centered instruction at the beginning and …

Thriving In The Age Of Ai: Navigating Ai Identity Threat Through Ai Job Crafting, Yuming He

Theses and Dissertations in Business Administration

As artificial intelligence (AI) technologies like GenAI tools increasingly reshape the workplace, employees increasingly face threats to their work identity. Grounded in the identity threat response model and job crafting theory, this study investigates how AI identity threat influences employee AI job crafting behaviors and how these behaviors, in turn, affect vitality and learning. Using survey data from 521 full-time employees who actively engage with AI tools, the results indicate that AI identity threat stimulates both AI approach job crafting and AI avoidance job crafting. AI approach crafting enhances both vitality and learning, while AI avoidance crafting only supports vitality. …

Property Testing Ai: An Efficient Frontier, Paul Sopher Lintilhac

Dartmouth College Ph.D Dissertations

In this dissertation, we take a step towards addressing the major problem of a lack of standardized and rigorous approaches to testing and evaluation of AI systems. Taking inspiration from both the fields of Property Testing and Property Based Testing (for programs), we develop a novel taxonomy of partially overlapping classes of properties of AI systems, including simple properties, compound properties, higher order properties, data relation properties, and architecture-utility properties. We argue that this taxonomy categorizes a diverse set of AI traits -- including accuracy, fairness, robustness, monotonicity, point-wise and global privacy properties, sensitivity, and more -- according to the …

Final Butte Priority Soils Operable Unit (Bpsou) Unreclaimed Sites: Ur-03 Site Remedial Action Work Plan (Rawp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Final Bpsou Unreclaimed Sites: Ur-05 Remedial Action Work Plan (Rawp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Association Of Sirt6 Expression With Risk Of Pneumonitis Induced By Radiotherapy In Cancer Patients, Fengyuan Yu, Zheng Gong, Yuan Li, Danial F Naseem, Chen Li, Miaowei Wen, Bingying Zhao, Zhezhe Xu, Shanshan Zhang, Rukun Zang, Ailu Wu, Qingxin Han, Shuhui Wu, Hongwei Li, Yipeng Song

Faculty, Staff and Student Publications

Thoracic tumours represent a significant proportion of malignant cancers. While radiotherapy (RT) improves prognosis, it can also lead to side effects such as radiation-induced pneumonitis (RP). Since SIRT6 is involved in DNA repair, energy metabolism and inflammation, this study aims to investigate the expression of SIRT6 in lymphocytes as a potential biomarker and therapeutic target for RP. This study included 170 patients diagnosed with thoracic tumours, all of whom underwent thoracic RT. RP was evaluated and classified as severe RP (SRP) and lower as non-severe RP (NSRP). Analyses were performed using SPSS version 26.0 and the R. Among 170 patients …

Trem2 Depletion In Pancreatic Cancer Elicits Pathogenic Inflammation And Accelerates Tumor Progression Via Enriching Il-1Β+ Macrophages, Daowei Yang, Xinlei Sun, Hua Wang, Ignacio I Wistuba, Huamin Wang, Anirban Maitra, Yang Chen

Faculty, Staff and Student Publications

Background & aims: Pancreatic ductal adenocarcinoma (PDAC) has a complex tumor microenvironment enriched with tumor-associated macrophages. Triggering receptor expressed on myeloid cells 2 (TREM2) is highly expressed by a subset of macrophages in PDAC. However, the functional role of TREM2 in PDAC progression remains elusive.

Methods: We generated a novel transgenic mouse model (KPPC;Trem2-/-) that enables the genetic depletion of TREM2 in the context of spontaneous PDAC development. Single-cell RNA-sequencing analysis was used to identify changes in the tumor immune microenvironment on TREM2 depletion. We evaluated the impacts of TREM2 depletion on the tumor immune microenvironment to elucidate the functions …

Nlrp3 Inflammasome Activation Expands The Immunosuppressive Myeloid Stroma And Antagonizes The Therapeutic Benefit Of Sting Activation In Glioblastoma, Spencer T Lea, Chao-Hsien Chen, Jun Wei, Ivana William, Inés Lopez Del Castillo, Michael A Curran

Faculty, Staff and Student Publications

Glioblastoma (GBM) is the most common and deadly primary brain malignancy and is clinically refractory to immunotherapy. Active NLRP3 inflammasome signaling and IL-1β secretion have been observed in GBM, and NLRP3-driven myeloid-derived suppressor cell (MDSC) recruitment can mediate cancer immune evasion. Agonists of the cytosolic double-stranded DNA-sensing stimulator of IFN gene (STING) pathway can mediate proinflammatory conversion of cancer MDSCs; however, secretion of the NLRP3 products IL-1β and IL-18 has also been observed in certain myeloid populations following STING activation. In this study, we aimed to determine both the potential mechanistic synergy between STING and NLRP3 agonists, and the effects …

Bispecific Antibodies In Hematologic And Solid Tumors: Current Landscape And Therapeutic Advances, Lorenzo Guidi, Julian Etessami, Carmine Valenza, Augusto Valdivia, Funda Meric-Bernstam, Enriqueta Felip, Giuseppe Curigliano

Faculty, Staff and Student Publications

Bispecific antibodies (bsAbs) have emerged as a novel class of therapeutics, offering a dual-targeting strategy to enhance the therapeutic efficacy of monoclonal antibodies, which is often limited by tumor heterogeneity and the occurrence of resistance mechanisms. By simultaneously engaging two distinct antigens or pathways, bsAbs disrupt multiple signaling cascades simultaneously, preventing escape mechanisms and offering a more durable response. Furthermore, they can optimize immune activation, improving immune cell recruitment strategies. In particular, T-cell engager bsAbs facilitate immune cell-mediated tumor destruction by linking T cells to tumor antigens. Instead, dual immune checkpoint inhibitors (CPIs) enhance immune activation by blocking inhibitory signals. …

Egfr Controls Transcriptional And Metabolic Rewiring In Krasg12d Colorectal Cancer, Dana Krauß, Veronica Moreno-Viedma, Emi Adachi-Fernandez, Cristiano De Sá Fernandes, Jakob-Wendelin Genger, Ourania Fari, Bernadette Blauensteiner, Dominik Kirchhofer, Nikolina Bradaric, Valeriya Gushchina, Georgios Fotakis, Thomas Mohr, Ifat Abramovich, Inbal Mor, Martin Holcmann, Andreas Bergthaler, Arvand Haschemi, Zlatko Trajanoski, Juliane Winkler, Eyal Gottlieb, Maria Sibilia

Faculty, Staff and Student Publications

Inhibition of the epidermal growth factor receptor (EGFR) shows clinical benefit in metastatic colorectal cancer (CRC) patients, but KRAS-mutations are known to confer resistance. However, recent reports highlight EGFR as a crucial target to be co-inhibited with RAS inhibitors for effective treatment of KRAS mutant CRC. Here, we investigated the tumor cell-intrinsic contribution of EGFR in KRASG12D tumors by establishing murine CRC organoids with key CRC mutations (KRAS, APC, TP53) and inducible EGFR deletion. Metabolomic, transcriptomic, and scRNA-analyses revealed that EGFR deletion in KRAS-mutant organoids reduced their phenotypic heterogeneity and activated a distinct cancer-stem-cell/WNT signature associated with reduced cell size …

Targeted Sting Activation Using Modified Ultrasound-Responsive Microbubbles Enhances Immune Checkpoint Blockade Against Melanoma, Sina Khorsandi, Kristin Huntoon, Yifan Wang, Adam Woodward, Abin Antony, Connor Endsley, Nazia Hafeez, Jared L Edwards, Nicole Mccuen, Prasanna G Alluri, Betty Y S Kim, Wen Jiang, Jacques Lux

Faculty, Staff and Student Publications

Despite the recent successes of immune checkpoint inhibitors (ICIs) in treating advanced melanoma, durable clinical responses still remain limited. To boost immune responses, agents that target immune regulators, such as the Stimulator of Interferon Genes (STING) agonist cyclic GMP-AMP (cGAMP), are being investigated. However, their clinical translation is impeded by poor serum stability, rapid tissue clearance, and T-cell death due to off-target activation. Recently, a novel strategy termed Microbubble-assisted UltraSound-guided Immunotherapy of Cancer (MUSIC) has been reported to selectively deliver cGAMP directly into the cytosol of antigen-presenting cells with spatiotemporal control. The resulting activation of STING and downstream proinflammatory pathways …

Breakthrough Infection And Death After Covid-19 Vaccination: A Physics Perspective, Seyed Ali Reza Mortazavi, Abdollah Jafarzadeh, Abdolkarim Ghadimi-Moghadam, Seyed Mohammad Javad Mortazavi, Masoud Haghani, Ali Ghadimi-Moghadam, Lembit Sihver

Informatics and Engineering Systems Faculty Publications

The largest universal immunization in history has occurred as a result of the COVID-19 pandemic. The developed COVID-19 vaccines have been shown to provide protection against severe forms of COVID-19 by inducing anti-spike neutralizing antibodies. It has been found that individuals who have not been vaccinated against COVID-19 were more likely to contract the virus during a period when the Delta variant was dominant, as compared to those who have received the complete dose of the vaccine, irrespective of the variant. However, there is no notable disparity in the likelihood of hospitalization, requirement for mechanical ventilation, or mortality between the …

A Concise Formalization Of Partial Falsifiability, Water Logic, And Neither Nor Logic With Neutrosophic Logic, Takaaki Fujita, Florentin Smarandache, Victor Christianto

Neutrosophic Sets and Systems

No abstract provided.

Interval Valued Fermatean Neutrosophic For Analysis Risk Management Of Practical Teaching Quality In University Art And Design Programs, Yu Cai

Neutrosophic Sets and Systems

No abstract provided.

Machine Learning Models With Neutrosophic Numbers For Network Anomaly Detection And Security Defense Technology, Hussein S. Al-Khazraji, Ahmed M. Alkhamees, Humam M. Al-Doori, Ahmed A. Metwaly, Mohamed Eassa, Ahmed Abdelhafeez, Ahmed Salama S., Ahmad M. Nagm

Neutrosophic Sets and Systems

No abstract provided.

Assessing Teaching Effectiveness In Journalism And Communication: A Data-Driven Perspective Using Hypersoft Set, Xiaoxi Zhang

Neutrosophic Sets and Systems

No abstract provided.

Analysis Factors Of Ideological And Political Education In Colleges And Universities In The New Media Era Under The Fermatean Neutrosophic Sets, Wei Zhao

Neutrosophic Sets and Systems

No abstract provided.