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The Shorthorn: August 29, 1984 Aug 2026

The Shorthorn: August 29, 1984

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


The Shorthorn: August 1, 1984 Aug 2026

The Shorthorn: August 1, 1984

The Shorthorn Newspaper Collection: 1980s

No abstract provided.


Caldwell Clean‑Water Engine (Ccwe‑1.0) Unified Cavitation‑Plasma, Microbubble, Atmospheric, And Polishing Architecture For Pfas, Microplastic, Pathogen, And Brine‑Grade Contaminant Reduction, Michael Victor Caldwell Mr. Aug 2026

Caldwell Clean‑Water Engine (Ccwe‑1.0) Unified Cavitation‑Plasma, Microbubble, Atmospheric, And Polishing Architecture For Pfas, Microplastic, Pathogen, And Brine‑Grade Contaminant Reduction, Michael Victor Caldwell Mr.

Defensive Publications Series

CCWE‑1.0 is a modular, container‑scale clean‑water engine that accepts:

  • Floodwater

  • Sewage‑contaminated surface water

  • Industrial brines

  • Saline wells

  • Atmospheric humidity

and outputs:

  • Potable water (where validated)

  • Decontaminated non‑potable water (for industrial/ag use)

  • Mapped waste streams (sludge, spent media, brine)

It integrates:

  • Hydrodynamic cavitation (CPR‑1.0)

  • Plasma‑assisted destruction (CPR‑1.0)

  • Microbubble oxidation (MBR‑1.0)

  • Conventional filtration and adsorption (POL‑1.0)

  • Atmospheric water harvesting (AWH‑1.0)

  • Telemetry and safety control (CTL‑1.0)

  • Waste stream handling (WST‑1.0)

  • Power and structural backbone (PWR‑1.0)

All subsystems use standard industrial components and conservative operating envelopes so labs, utilities, and humanitarian teams can build, test, and iterate without proprietary parts or hidden parameters.


Mainehealth Investigator Vignettes - August 2026 Aug 2026

Mainehealth Investigator Vignettes - August 2026

Journal of Maine Medical Center

No abstract provided.


Breaking The Parallax: Big Tech In India, Dr. Pratiksha Ashok Aug 2026

Breaking The Parallax: Big Tech In India, Dr. Pratiksha Ashok

National Law School Business Law Review

This paper examines the role of Big Tech in India through the conceptual lens of parallax, understood as the analytical distortion that arises when platform power is assessed from shifting institutional, legal, and geopolitical vantage points. Existing scholarship and policy debates tend to frame Big Tech in India either through Global North regulatory paradigms emphasizing monopoly power, market foreclosure, and the need for ex-ante constraints or through a domestic developmental narrative that positions digital platforms as engines of innovation, inclusion, and infrastructural expansion. This paper argues that neither perspective, taken in isolation, adequately captures the legal and political economy of …


From Covert Use To Structured Oversight: A Framework For Institutional Governance Of Artificial Intelligence In Graduate Medical Education, Samuel R. Briggs, Bita Behrouzi, Robert Hayden Aug 2026

From Covert Use To Structured Oversight: A Framework For Institutional Governance Of Artificial Intelligence In Graduate Medical Education, Samuel R. Briggs, Bita Behrouzi, Robert Hayden

Journal of Maine Medical Center

Problem Statement: Artificial intelligence (AI) tools are routinely used by residents and fellows across graduate medical education. The Accreditation Council for Graduate Medical Education has no AI-specific policy nor requirement for disclosure norms, leaving programs and attending physicians without a standard framework for supervising AI-assisted trainee work. The result is a training environment in which AI use is simultaneously widespread and under-governed by operating without the policies and supervisory frameworks needed to make that use educationally productive.

Background: AI tools are now embedded across health system workflows, and their use has expanded beyond clinical documentation into education, research, and scholarly …


Intensification Of Thermal Energy Storage Systems Based On Sodium Nitrate, Hari Suthan V Mr Aug 2026

Intensification Of Thermal Energy Storage Systems Based On Sodium Nitrate, Hari Suthan V Mr

Theses and Dissertations

Thermal energy storage (TES) systems employing phase change materials (PCM) bridge the gap between thermal energy demand and supply. The low thermal conductivity of sodium nitrate (NaNO3), an inorganic PCM for high-temperature TES systems restricts charging and discharging kinetics, reducing system-level performance. This thesis investigates the intensification of sodium nitrate-based thermal energy storage systems through the incorporation of different classes of additives. Metal oxides (zinc oxide and aluminium oxide) and carbon-based materials (graphene oxide (GO) and expanded graphite (EG)), were incorporated into NaNO3 to improve its thermophysical properties (thermal conductivity, latent heat, specific heat).

Composites were prepared using low-energy ball …


Understanding The Long-Term Patterns Of Change Of A Tidal Marsh In Mission Bay, San Diego, California, Carrie A. Shuster, Theresa Sinicrope Talley Ph.D., Drew Talley Ph.D., Zhi-Yong Yin Ph.D., Kellie Uyeda Ph.D. Aug 2026

Understanding The Long-Term Patterns Of Change Of A Tidal Marsh In Mission Bay, San Diego, California, Carrie A. Shuster, Theresa Sinicrope Talley Ph.D., Drew Talley Ph.D., Zhi-Yong Yin Ph.D., Kellie Uyeda Ph.D.

Theses

Coastal marshes are among California’s most productive ecosystems and the most impacted, having been extensively modified by dredging, filling, and urban development. This thesis investigates over a century of change for a marsh in Northern Mission Bay, San Diego, California using ecological and spatial analyses.

Chapter 1 provides an overview of the environmental history and current land use of the Northern Mission Bay marsh, tracing changes from pre-contact Indigenous stewardship through colonial and modern urban development. It also introduces a restoration plant palette derived from historical and contemporary species occurrences, ecological functions, and documented cultural uses. By integrating ethnobotanical knowledge …


A Modeling Scenario For Cooling A Hot Vehicle In Florida, Jared Bunn, Bernadette Mullins, Elizabeth Hale, Jaeyoun Oh Aug 2026

A Modeling Scenario For Cooling A Hot Vehicle In Florida, Jared Bunn, Bernadette Mullins, Elizabeth Hale, Jaeyoun Oh

CODEE Journal

This paper presents a group project assigned in a Calculus 2 course that has students work to develop, analyze, and draw conclusions about a modeling scenario for cooling a hot car. Using a modeling-first approach, instructors supported the students in class throughout the beginning of the project, enabling the groups to complete the remainder of the project on their own. Students used parameter estimation to tune their models to provided data: one for windows being up, and one for windows being down. This project provides an example of how modeling can be introduced early in a calculus course, rather than …


Supporting Graduate Student Flourishing: Development Of A Whole-Person Formation Framework Through A University-Wide Task Force, Elisa Greene, Amanda Grieme-Bradley, Maren Bishop Aug 2026

Supporting Graduate Student Flourishing: Development Of A Whole-Person Formation Framework Through A University-Wide Task Force, Elisa Greene, Amanda Grieme-Bradley, Maren Bishop

Papers

How do whole persons form for lives of character and flourishing within graduate schooling years? What steps could an institution take to move toward that end? This work describes the process of one institution’s use of a task force examining these questions using a combination of literature review and structured interviews with key stakeholders across campus. The context of the institution’s unique mission, vision, and virtue framework provided a foundation out of which four areas of focus emerged: 1) infrastructure and representation, 2) belonging and community, 3) communication, and 4) professional identity formation. Investment in these institutional themes supports formation …


Disentangling The Hemodynamic Effects Of A-Wave Loss And Cardiac Output Reduction In Atrial Fibrillation, Hailey Labonte, Ahmad Bshennaty, Ghasaq Saleh, Salameh Al-Halaseh, Mohamad Alkhouli, Hoda Hatoum Aug 2026

Disentangling The Hemodynamic Effects Of A-Wave Loss And Cardiac Output Reduction In Atrial Fibrillation, Hailey Labonte, Ahmad Bshennaty, Ghasaq Saleh, Salameh Al-Halaseh, Mohamad Alkhouli, Hoda Hatoum

Michigan Tech Publications

Purpose: Atrial fibrillation (AF) increases thromboembolic risk, yet the relative hemodynamic contributions of A-wave loss, cardiac output (CO) reduction, and patient-specific atrial geometry remain incompletely understood. This study aimed to isolate the hemodynamic consequences of A-wave removal and CO reduction on left atrial (LA) flow and stasis. Methods: Five patient-specific LA geometries were evaluated using transient laminar CFD simulations. For each geometry, the sinus rhythm transmitral waveform was used as the baseline and modified to represent AF with compromised and conserved CO. Hemodynamic endpoints included LA velocity, time-averaged wall shear stress (TAWSS), relative residence time (RRT), oscillatory shear index (OSI), …


Lanthorn, Vol. 61, No. 01, August 10, 2026, Grand Valley State University Aug 2026

Lanthorn, Vol. 61, No. 01, August 10, 2026, Grand Valley State University

Volume 61, August 10, 2026 – current

Lanthorn is Grand Valley State's student newspaper, published from 1968 to the present.


It Takes A Community: Barbershops As Healing Spaces For Black Men, Aron Anthony King, Piri W. Ackerman, Patricia Fernandez Aug 2026

It Takes A Community: Barbershops As Healing Spaces For Black Men, Aron Anthony King, Piri W. Ackerman, Patricia Fernandez

International Nursing Research Congress (INRC)

Black men in the United States experience disproportionately poor mental health outcomes yet remain significantly underrepresented in accessing care. According to the U.S. Department of Health and Human Services Office of Minority Health, African American adults are 20% more likely to report serious psychological distress and are more likely to experience feelings of sadness, hopelessness, and worthlessness compared to their white counterparts. Despite these disparities, less than half of Black men experiencing mental illness seek treatment. Intersecting factors such as racism, stigma, medical mistrust, and traditional notions of masculinity contribute to these gaps, highlighting the need for more culturally responsive …


Strategies For Successful Postgraduation Next Generation Nclex (Ngn) Preparation, Kristy P. Ludy Aug 2026

Strategies For Successful Postgraduation Next Generation Nclex (Ngn) Preparation, Kristy P. Ludy

International Nursing Research Congress (INRC)

Background and Problem: In 2023, the Next Generation NCLEX (NGN) was implemented after a strategic practice analysis conducted by the National Council of State Boards of Nursing (NCSBN) to improve evaluation of Clinical Judgment and decision-making of nursing graduates (Jessee et al., 2023; Poorman & Mastorovich, 2020). Initially, first-time pass rates (FTPRs) rose after the NGN’s implementation, but have fluctuated on national and state levels (National Council of State Boards of Nursing, 2025). Nursing faculty have been focused on preparing students for the NGN (Boev, 2023; Sturdivant & Allen-Thomas, 2022). However, becoming aware of how graduates prepare after graduation and …


Translational Reading Frame Predicts The Pathogenicity Of C-Terminal Frameshift Deletions In Mecp2, Jacky Guy, Elena Hein, Beatrice Alexander-Howden, Timur Von Bock Und Polach, Tricia Mathieson, Benjamin P Kleinstiver, Huda Y Zoghbi, Adrian Bird Aug 2026

Translational Reading Frame Predicts The Pathogenicity Of C-Terminal Frameshift Deletions In Mecp2, Jacky Guy, Elena Hein, Beatrice Alexander-Howden, Timur Von Bock Und Polach, Tricia Mathieson, Benjamin P Kleinstiver, Huda Y Zoghbi, Adrian Bird

Duncan NRI Faculty and Staff Publications

Mutations in the MECP2 gene cause the severe neurological disorder Rett syndrome. A cluster of frameshift-causing C-terminal deletions (CTDs) removes ~100 amino acids and accounts for approximately 10% of RTT-causing mutations. Their pathogenicity is unexpected because this C-terminal domain is dispensable in mice. Analysis of pathogenic and benign human MECP2 variants reveals that some individuals with apparently typical CTDs do not develop Rett syndrome, confirming that C-terminal truncations are not intrinsically pathogenic. Using human sequence data and mouse models we show that pathogenicity results from a marked reduction in MeCP2 levels and depends on the presence of a proline proline …


Functionality Risk Assessment And Risk-Based Management For Critical Infrastructure Systems, Anteneh Zewdu Deriba Aug 2026

Functionality Risk Assessment And Risk-Based Management For Critical Infrastructure Systems, Anteneh Zewdu Deriba

Dissertations and Theses

Critical infrastructure systems such as transportation networks serve as the lifelines of modern society, supporting economic activity and ensuring access to critical services. Their disruption under extreme events can produce consequences extending far beyond physical damage to individual assets. In transportation networks for instance, failures of critical assets such as bridges and tunnels can reduce accessibility of communities, limit freight capabilities for commerce, and increase travel distance and travel time of road users. These consequences associated with the system functionality loss are tied not only to the physical vulnerability and failure of individual assets, but also to the system configuration …


Malt1 Protease Inhibition Restrains Glioblastoma Progression By Reversing Tumor-Associated Macrophage-Dependent Immunosuppression In Mice, Juliana Hofstätter Azambuja, Saigopalakrishna Yerneni, Lisa Maurer, Hannah Crentsil, Gabriela Debom, Linda Klei, Mei Smyers, Chaim Sneiderman, Kristina Schwab, Rajesh Acharya, Aivi Nguyen, Josie Emery, John Little, Jeffrey Meridew, Yijen Lin Wu, Prasanna Ekambaram, Dong Hu, Pete Gough, John Bertin, Ari Melnick, Gary Kohanbash, Riyue Bao, Peter Lucas, Linda Mcallister-Lucas Aug 2026

Malt1 Protease Inhibition Restrains Glioblastoma Progression By Reversing Tumor-Associated Macrophage-Dependent Immunosuppression In Mice, Juliana Hofstätter Azambuja, Saigopalakrishna Yerneni, Lisa Maurer, Hannah Crentsil, Gabriela Debom, Linda Klei, Mei Smyers, Chaim Sneiderman, Kristina Schwab, Rajesh Acharya, Aivi Nguyen, Josie Emery, John Little, Jeffrey Meridew, Yijen Lin Wu, Prasanna Ekambaram, Dong Hu, Pete Gough, John Bertin, Ari Melnick, Gary Kohanbash, Riyue Bao, Peter Lucas, Linda Mcallister-Lucas

College of Life Sciences Faculty Papers

MALT1 protease is an intracellular signaling molecule that promotes tumor progression via cancer cell-intrinsic and cancer cell-extrinsic mechanisms. MALT1 has been mostly studied in lymphocytes, and little is known about its role in tumor-associated macrophages. We show that MALT1 is expressed in glioblastoma (GBM)-associated macrophages. Mechanistically, GBM tumor cells induce a MALT1-NF-κB signaling axis in macrophages, leading to enhanced macrophage migration and polarization toward an immunosuppressive ('M2-like') phenotype. Inactivation of MALT1 protease promotes transcriptional reprogramming that reduces migration and restores a macrophage anti-tumor 'M1-like' phenotype. Preclinical in vivo analysis shows that MALT1 inhibitor treatment results in immuno-reactivity of GBM-associated macrophages …


Automated Classification, Measurement, And Semantic Segmentation Of Open-Web Joists From Point Cloud Data, Justin Raymond Dworacek Aug 2026

Automated Classification, Measurement, And Semantic Segmentation Of Open-Web Joists From Point Cloud Data, Justin Raymond Dworacek

Theses and Dissertations

This thesis presents a BIM-oriented methodology for the automated classification, measurement, and segmentation of structural trusses from point cloud data. A real truss point cloud and a complementary synthetic dataset derived from CADBIM Revit families were used to develop and evaluate the workflow. Classification was performed using a rule-based Python algorithm based on principal component analysis, side-view feature extraction, and family-specific geometric decision logic, while a separate family-aware script was used to extract key truss dimensions. Semantic segmentation was evaluated using a PointTransformerV3 model to separate truss and non-truss points in mixed point cloud scenes. The results demonstrated strong performance …


A Graphical Approach To Isospectral Unfoldings, Dallin Seyfried Aug 2026

A Graphical Approach To Isospectral Unfoldings, Dallin Seyfried

Theses and Dissertations

Isospectral reductions are mathematical techniques used to shrink a matrix, or a graph, into a smaller, dimensionally reduced form while preserving its spectrum. Simple graphs that share isospectral reductions also share quantum walk properties. As such we further develop the inverse process, isospectral unfoldings, to find graphs that share isospectral reductions. We first prove many conditions relating to isospectral reductions and unfoldings. Afterwards, we define two new unfolding processes: general unfolding which unfolds the graph one vertex at a time, and equitable partition unfolding which excels at larger graph unfolding. In particular, through equitable partition unfolding, we discover many graphs …


Vedic Mathematics And Mental Computation: Fast Multiplication Techniques, Algebraic Foundations, And Historical Perspectives, Rakesh Bhatia, Mrinal Kanti Roychowdhury Aug 2026

Vedic Mathematics And Mental Computation: Fast Multiplication Techniques, Algebraic Foundations, And Historical Perspectives, Rakesh Bhatia, Mrinal Kanti Roychowdhury

School of Mathematical & Statistical Sciences Faculty Publications

Mental computation has fascinated mathematicians, educators, and students for centuries. Various computational techniques allow arithmetic calculations to be performed rapidly without the use of calculators or computers. Among these methods, several popular techniques are associated with what is commonly known as Vedic Mathematics. In this article, we examine a collection of fast multiplication techniques, including multiplication near powers of ten, multiplication by eleven, squaring numbers ending in five, and the vertical-and-crosswise method. For each technique, we provide elementary mathematical explanations based on algebraic identities and place-value representations.


Recalibrating Risk: A Call For South Asian-Focused Heart Failure Prediction Models, Nandini Nair, Dongping Du, Aiswarya J. Pillai, Swarna Mahesh, Mrudula R. Munagala, Howard J. Eisen, Balakrishnan Mahesh Aug 2026

Recalibrating Risk: A Call For South Asian-Focused Heart Failure Prediction Models, Nandini Nair, Dongping Du, Aiswarya J. Pillai, Swarna Mahesh, Mrudula R. Munagala, Howard J. Eisen, Balakrishnan Mahesh

Division of Cardiology Faculty Papers

Background: Heart failure (HF) represents the final common pathway of diverse cardiovascular disorders, including coronary artery disease, primary myocardial pathology, and abnormalities of cardiac conduction. These conditions arise from an interplay of genetic, environmental, and psychosocial influences, making it essential to understand these determinants to improve risk prediction and prevention. Multiple biological pathways of inflammation, fibrosis, coagulation, oxidative stress, lipid dysregulation, endothelial dysfunction, and metabolic disturbances are shaped by inherited susceptibility and modifiable exposures. Together, these mechanisms drive HF development and progression, though their relative contributions vary across populations. Methods: PubMed and Google Scholar were searched for clinical, biomedical, and …


The Use Of Machine Learning Models For Predicting The Dielectric Strength Of Gases, Matthew Mileski, Paul W. Groth, Timothy S. Wolfe, Adib J. Samin Aug 2026

The Use Of Machine Learning Models For Predicting The Dielectric Strength Of Gases, Matthew Mileski, Paul W. Groth, Timothy S. Wolfe, Adib J. Samin

Faculty Publications

Technological advancements in high voltage systems have pushed sulfur hexafluoride (SF6) to its operational limits. Furthermore, this gas has other drawbacks including a high liquefaction temperature and a high global warming potential. Therefore, there has been an urgent need to find alternative gases with high dielectric strength (DS). In this work, density functional theory (DFT) is used to calculate molecular descriptors that are fed into an artificial neural network (ANN) and a random forest (RF). These machine learning (ML) models are then used to predict the DS for hundreds of molecules. A finite element model (FEM) is also used to …


Effective Visibility In The Infrared Bands, Peter L. Dean-Erlander, Steven T. Fiorino, Ronald G. Driggers Aug 2026

Effective Visibility In The Infrared Bands, Peter L. Dean-Erlander, Steven T. Fiorino, Ronald G. Driggers

Faculty Publications

Visibility is an atmospheric metric for the comparison of terrestrial imaging conditions and locations. A limitation of visibility is that it is defined for the visible spectrum only, and there is no simple infrared equivalent. This study compares three reflective infrared wavebands: near-IR (NIR), shortwave IR (SWIR), and extended shortwave IR (eSWIR), to the visible band across a global set of cities to develop three rule-of-thumb functions for IR effective visibility. To accomplish this, a radiometric sensor model is combined with the Laser Environmental Effects Definition and Reference (LEEDR) software package to calculate the visibility of a black-and-white contrast target …


An Atmospheric Optical Turbulence Structure Parameter Measurements System Based On Direct Ri Sensing Using High-Resolution Fiber-Optic Sensors, Matej Njegovec, Simon Pevec, Vedran Budinski, Boris Macuh, Melissa K. Beason, Denis Onlagic Aug 2026

An Atmospheric Optical Turbulence Structure Parameter Measurements System Based On Direct Ri Sensing Using High-Resolution Fiber-Optic Sensors, Matej Njegovec, Simon Pevec, Vedran Budinski, Boris Macuh, Melissa K. Beason, Denis Onlagic

Faculty Publications

The paper presents a method to characterize the refractive index structure parameter (Cn2) associated with optical turbulence directly. The characterization system is based on miniature, high‑resolution, all‑fiber refractive index (RI) sensors. The refractive index sensors employ open‑path, low‑finesse Fabry–Perot interferometers that are approximately 8 mm long and 200 μm in diameter. The active part of the interferometers is made of ultra‑low‑expansion glass, which eliminates the influence of thermal expansion on the refractive index measurements. The proposed refractive index sensor, operating in a differential configuration, achieved a resolution of 2×10-9 RIU using a custom‑designed spectral interrogation system …


Cigarette Smoke Induces Fasn-Dependent Fatty Acid Metabolic Rewiring To Drive Bladder Cancer Progression, Chandra Sekhar Amara, Danthasinghe Waduge Badrajee Piyarathna, Abu Hena Mostafa Kamal, Yuen San Chan, Karthik Reddy Kami Reddy, Chandra Shekar R Ambati, Mohammed Khurshidul Hassan, Pratik Shriwas, Tanmay Gandhi, Antrix Jain, Tanja Gangnus, Pooja Popli, Roshan Borkar, Sung Wook Kang, Silvia L Summers, Vasanta Putluri, Sandra L Grimm, Sharan Venkatesh, Ningxin Song, Erin H Seeley, Jenna Hedlich-Dwyer, Shu-Hsia Chen, Nupam P Mahajan, Abhinav K Jain, Lacey Elizabeth Dobrolecki, Gabrielle A Wells, Hugo Villanueva, Jenny Li, Xuefeng Liu, Roni J Bollag, Anna Malovannaya, Sung Yun Jung, Hyun-Sung Lee, Irfan A Asangani, Martha K Terris, Chad J Creighton, Leomar Y Ballester, Balasubramanyam Karanam, Suyu Liu, Minjae Lee, Rajeeva R Raju, M Minhaj Siddiqui, Livia S Eberlin, Ramakrishna Kommagani, Arun Sreekumar, Jianjun Gao, Nicolas L Young, H Courtney Hodges, Cristian Coarfa, Natalie R Gassman, Seth P Lerner, Yair Lotan, Nagireddy Putluri Aug 2026

Cigarette Smoke Induces Fasn-Dependent Fatty Acid Metabolic Rewiring To Drive Bladder Cancer Progression, Chandra Sekhar Amara, Danthasinghe Waduge Badrajee Piyarathna, Abu Hena Mostafa Kamal, Yuen San Chan, Karthik Reddy Kami Reddy, Chandra Shekar R Ambati, Mohammed Khurshidul Hassan, Pratik Shriwas, Tanmay Gandhi, Antrix Jain, Tanja Gangnus, Pooja Popli, Roshan Borkar, Sung Wook Kang, Silvia L Summers, Vasanta Putluri, Sandra L Grimm, Sharan Venkatesh, Ningxin Song, Erin H Seeley, Jenna Hedlich-Dwyer, Shu-Hsia Chen, Nupam P Mahajan, Abhinav K Jain, Lacey Elizabeth Dobrolecki, Gabrielle A Wells, Hugo Villanueva, Jenny Li, Xuefeng Liu, Roni J Bollag, Anna Malovannaya, Sung Yun Jung, Hyun-Sung Lee, Irfan A Asangani, Martha K Terris, Chad J Creighton, Leomar Y Ballester, Balasubramanyam Karanam, Suyu Liu, Minjae Lee, Rajeeva R Raju, M Minhaj Siddiqui, Livia S Eberlin, Ramakrishna Kommagani, Arun Sreekumar, Jianjun Gao, Nicolas L Young, H Courtney Hodges, Cristian Coarfa, Natalie R Gassman, Seth P Lerner, Yair Lotan, Nagireddy Putluri

Faculty, Staff and Students Publications

Cigarette smoke promotes bladder tumor growth by enhancing cancer cell survival and proliferation through smoke mediated carcinogens. FASN, a key enzyme in fatty acid synthesis, is dysregulated in many cancers and correlates with aggressive phenotypes. In this study, we demonstrate elevated fatty acid levels and FASN specifically in smokers with bladder cancer. Elevated FASN under smoke exposure imparted epigenetic alterations, particularly histone acetylation, impacts DNA repair and DNA-binding transcription factors which regulate metabolic pathways. Under cigarette smoke, bladder cancer cells undergo a metabolic shift, utilizing glutamine as a major carbon source through reductive carboxylation to fuel fatty acid biosynthesis via …


Enabling Asl Digital Communication Under Poor Internet Access, Swann Thantsin Aug 2026

Enabling Asl Digital Communication Under Poor Internet Access, Swann Thantsin

Student Theses

Video conferencing degrades asymmetrically. When bandwidth falls, a hearing caller loses picture quality and keeps the conversation; a deaf and hard of hearing signer, whose language is carried entirely in the visual modality, loses the conversation. This thesis asks whether signed video reduced to the rates at which commercial platforms fail can be reconstructed at the receiver well enough to keep signing legible. A twostage reduction pipeline crops to the signer and transmits the face and hands at higher fidelity than their surroundings, achieving a reduction of approximately 99%; reconstruction uses a recurrent bottleneck mixer architecture, trained both conventionally and …


Robustness Assessment Of Head And Neck Proton Therapy Plans Using Composite Synthetic Cts: A Preliminary Step Toward Ai Driven Anatomy Prediction Planning: A Retrospective Dosimetric Study., Ryan Michael Rodriguez Aug 2026

Robustness Assessment Of Head And Neck Proton Therapy Plans Using Composite Synthetic Cts: A Preliminary Step Toward Ai Driven Anatomy Prediction Planning: A Retrospective Dosimetric Study., Ryan Michael Rodriguez

Masters Projects

Proton therapy is more commonly being utilized for head and neck cancer treatment due to its ability to reduce dose to the surrounding normal tissue. However, one of the biggest challenges in proton treatment is its sensitivity to changes in tissue density, often necessitating adaptive replanning. This study evaluated if incorporating additional synthetic CTs (sCT) datasets during robust optimization can create treatment plans that maintain target coverage and organ sparing despite anatomical changes better than the original nominal plan, thereby reducing the need for adaptive planning in head and neck proton treatment. Ten head and neck cancer patients who underwent …


Moss Biomonitoring And Isotopic Signatures Reveal Aviation Fuel As Local Lead Source Near Oregon Airports, Oluwaseyi E. Aderinboye, Alyssa E. Shiel, Lauren Stalford, Christina J. Murphy, Dean B. Atkinson Aug 2026

Moss Biomonitoring And Isotopic Signatures Reveal Aviation Fuel As Local Lead Source Near Oregon Airports, Oluwaseyi E. Aderinboye, Alyssa E. Shiel, Lauren Stalford, Christina J. Murphy, Dean B. Atkinson

Chemistry Faculty Publications and Presentations

Lead emissions from piston-engine aircraft using leaded aviation gasoline (avgas) remain a significant source of environmental contamination near regional airports, posing potential health risks to nearby communities. Passive biomonitoring using the epiphytic moss Orthotrichum lyellii was combined with lead isotope fingerprinting to quantify lead concentrations and distinguish between legacy leaded gasoline and current avgas emissions near Hillsboro and Troutdale airports in Oregon. Here we show that lead levels are elevated by up to 50 times the rural background near airports, with isotopic signatures confirming avgas as a dominant local source. These findings indicate that avgas use contributes substantially to environmental …


The Role Of Chimeric Antigen Receptor Regulatory T Cells In Promoting Immune Tolerance In Solid Organ Transplantation: Mechanisms And Therapeutic Potential, Maher S. Alwethaynani Aug 2026

The Role Of Chimeric Antigen Receptor Regulatory T Cells In Promoting Immune Tolerance In Solid Organ Transplantation: Mechanisms And Therapeutic Potential, Maher S. Alwethaynani

Saudi Medical Journal

Solid organ transplantation (SOT) is a life-saving procedure for patients with end-stage organ failure; however, lifelong immunosuppressant use is needed to prevent allograft rejection. These drugs increase the risk of non-Hodgkin lymphoma, liver, kidney, and lung cancers, and heighten susceptibility to oncogenic viruses, including hepatitis B and Epstein-Barr virus. The usage of chimeric antigen receptor (CAR) regulatory T (Treg) cells is a promising approach to induce transplant tolerance while minimizing dependence on immunosuppressants. The CAR Tregs offer the potential to enhance graft survival and quality of life by reducing immunosuppressant-related morbidity and mortality. Despite remarkable progress in transplantation tolerance, challenges …


Exploring Translational Medical Research Progress In G20 Countries: 5-Year Study, Hana A. Alhumud, Fars K. Alanazi, Edward B. Devol Aug 2026

Exploring Translational Medical Research Progress In G20 Countries: 5-Year Study, Hana A. Alhumud, Fars K. Alanazi, Edward B. Devol

Saudi Medical Journal

Objectives: Biomedical research is crucial for advancing medical knowledge and improving public health. However, the research process is often disjointed and lacks seamless progression, leading to delays and missed opportunities. To address this, the concept of translational research has emerged, focusing on the smooth transition of research results to the next stage of inquiry. Methods: This study analyzed approximately 40,000 research publications from the Web of Science database to identify research activities associated with translational research. Publications from Group of 20 (G20) countries over the past 5 years were examined to explore patterns of research focus and progress in this …