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Selective Alanine Transporter Utilization Is A Therapeutic Vulnerability In Arid1a-Mutant Ovarian Cancer, Hao Nie, Liping Liao, Rafal J Zielinski, Javier A Gomez, Akshay V Basi, Lin Tan, Wei Zhou, Heng Liu, Chen Wang, Shuai Wu, Yuan Qi, Taito Miyamoto, Federica Severi, Aaron R Goldman, Shengqing Gu, Anil K Sood, Amir A Jazaeri, Ronny Drapkin, Daniel T Claiborne, Nan Zhang, Philip L Lorenzi, Jared K Burks, Ernst Lengyel, Eyal Gottlieb, Rugang Zhang Jul 2025

Selective Alanine Transporter Utilization Is A Therapeutic Vulnerability In Arid1a-Mutant Ovarian Cancer, Hao Nie, Liping Liao, Rafal J Zielinski, Javier A Gomez, Akshay V Basi, Lin Tan, Wei Zhou, Heng Liu, Chen Wang, Shuai Wu, Yuan Qi, Taito Miyamoto, Federica Severi, Aaron R Goldman, Shengqing Gu, Anil K Sood, Amir A Jazaeri, Ronny Drapkin, Daniel T Claiborne, Nan Zhang, Philip L Lorenzi, Jared K Burks, Ernst Lengyel, Eyal Gottlieb, Rugang Zhang

Faculty, Staff and Student Publications

Subunits of the SWI/SNF chromatin remodeling complex are altered in ~20% of human cancers. Exemplifying the alterations is the ARID1A mutation that occurs in ~50% ovarian clear cell carcinoma (OCCC), a disease with limited therapeutic options. Here, we showed that ARID1A mutations create a dependence on alanine by regulating alanine transporters to increase intracellular alanine levels. ARID1A directly repressed alanine importer SLC38A2 and simultaneously promoted alanine exporter SLC7A8. ARID1A inactivation increased alanine utilization predominantly in protein synthesis and passively through the tricarboxylic acid cycle. Indeed, ARID1A-mutant OCCCs were hyper-sensitive to inhibition of SLC38A2. In addition, SLC38A2 inhibition enhanced chimeric antigen …

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Creativity And Curb Cuts: Experiences In Our First Offering Of A Front End Development And Accessibility Focused Cs Course, Briana C. Bettin, Tony Garnett, Alex Gore, Andrea Llanas Jul 2025

Creativity And Curb Cuts: Experiences In Our First Offering Of A Front End Development And Accessibility Focused Cs Course, Briana C. Bettin, Tony Garnett, Alex Gore, Andrea Llanas

Michigan Tech Publications

Students learn an abundance of technical skills while obtaining a computer science degree. The ability to develop meaningful front end user interfaces is often considered the domain of only ''more artistic'' CS students. However, for users to effectively engage with any piece of software, functional user interfaces are critical. Moreover, even among students who have front end skills, semantic and accessible design is all too often less considered. The first author piloted a ''Front End Development and Accessibility'' course this past Fall. This course teaches basic skills of front end with web and leverages key accessibility standards via WCAG. This …

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The Relative Importance Of Wind And Hydroclimate Drivers In Modulating Wind-Blown Dust Emissions In Earth System Models, Xinzhu Li, Longlei Li, Yan Feng, Xin Xi Jul 2025

The Relative Importance Of Wind And Hydroclimate Drivers In Modulating Wind-Blown Dust Emissions In Earth System Models, Xinzhu Li, Longlei Li, Yan Feng, Xin Xi

Michigan Tech Publications

Windblown dust emissions are subject to large uncertainties in Earth system models (ESMs), yet model discrepancies in dust variability and its physical drivers remain poorly understood. This study evaluates the consistency of 21 ESMs in simulating the climatological distribution and interannual variability of global dust emissions and applies dominance analysis to quantify the relative influence of near-surface wind speed and five hydroclimate variables (precipitation, soil moisture, specific humidity, air temperature, leaf area index) across different climate zones. In hyperarid regions, the models exhibit poor agreement in dust variability, with only 10 % of pairwise comparisons showing significant positive correlations. Most …

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Rutger Bregman's Centralized Utopia, Vladimir Snurenco Jul 2025

Rutger Bregman's Centralized Utopia, Vladimir Snurenco

University Faculty Publications and Creative Works

A short, provocative review of Rutger Bregman’s Moral Ambition. I sketch his technocratic utopia—“Rutger-land”—a colder, centralized world where fossil fuels are banned, richer people are taxed into moral compliance, UBI prevails, and the landscape is “tobacco-free, malaria-free, poverty-free, and meat-free… just fields of kale and solar panels.” I argue Bregman’s approach is resolutely top-down—activism, lobbying, and policy over enterprise, churches, and grassroots civic life—misunderstanding how wealth is created and how real change happens. Against this centralized moralism, I make the case for decentralization, subsidiarity, and the quiet, dignified work of civil society.

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Strategies Leaders In Affordable Housing Can Use To Decrease Property Management Turnover And Increase Professional Tenure, Marisa T. Baldwin-Woodhouse Jul 2025

Strategies Leaders In Affordable Housing Can Use To Decrease Property Management Turnover And Increase Professional Tenure, Marisa T. Baldwin-Woodhouse

Walden Dissertations and Doctoral Studies

Executive leaders of rental housing in the affordable housing sector have a high turnover rate of property managers, resulting in wasted time, compliance concerns, loss of institutional knowledge, deterioration of operational costs, and lost revenue, negatively impacting employee commitment. Grounded in the job embeddedness theory, the purpose of this qualitative pragmatic inquiry was to explore effective strategies that some executive leaders in affordable housing can use to decrease property manager turnover and increase professional tenure. The participants comprised eight executive leaders who oversaw property managers in affordable housing in the United States. Data were collected from semistructured interviews, and thematic …

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Soft Hexapod Robot With Tendon-Driven Continuum Legs For Internal Infrastructure Inspection, Setayesh Yavari Jul 2025

Soft Hexapod Robot With Tendon-Driven Continuum Legs For Internal Infrastructure Inspection, Setayesh Yavari

LSU Master's Theses

The need for robotic systems capable of operating in confined, hazardous, or complex environments has driven interest in soft and legged platforms for industrial inspection and structural integrity assessment. This thesis presents the design and fabrication of a tentacle-like, soft-legged hexapod robot, which uses six cable-stiffened, pre-curved, tendon-driven continuum robot (TDCR) legs. These biologically inspired legs are designed to offer a balance between compliance and control, enabling the robot to navigate unstructured terrains and potentially grasp cylindrical structures such as pipes. The design phase involved the development and comparison of multiple leg geometries using CAD modeling and finite element analysis …

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Major Concerns About Microelectronics, Elise Annett, Steven Hanson, James Giordano Jul 2025

Major Concerns About Microelectronics, Elise Annett, Steven Hanson, James Giordano

Strategic Insights

This commentary examines the critical role of secure microelectronics in enabling artificial intelligence (AI)–driven military capabilities and sustaining U.S. strategic advantage. As AI accelerates decision cycles, enhances intelligence, surveillance, and reconnaissance (ISR), and integrates with neurocognitive systems, its effectiveness depends on trusted semiconductor infrastructure. The authors warn that foreign-manufactured or compromised microelectronic components pose systemic risks to command and control, critical infrastructure, and operational continuity. Supply chain vulnerabilities, including embedded “rogue” devices, could enable sabotage or disruption in contested environments. The article recommends on-shoring microelectronics production, restricting off-shoring of mission-critical components, and strengthening defense-industrial oversight to ensure hardware integrity. Secure …

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The Feasibility Of Passively Tracking Children’S Tv Viewing And Mobile Device Use In Naturalistic Settings, Anil Kumar Vadathya, Jennette P Moreno, Alicia Beltran, Samah Haidar, Nimah Haidar, Sheryl O Hughes, Debbe Thompson, Salma M A Musaad, Tom Baranowski, Jason A Mendoza, Joseph Young, Akane Sano, Ashok Veeraraghavan Jul 2025

The Feasibility Of Passively Tracking Children’S Tv Viewing And Mobile Device Use In Naturalistic Settings, Anil Kumar Vadathya, Jennette P Moreno, Alicia Beltran, Samah Haidar, Nimah Haidar, Sheryl O Hughes, Debbe Thompson, Salma M A Musaad, Tom Baranowski, Jason A Mendoza, Joseph Young, Akane Sano, Ashok Veeraraghavan

Faculty, Staff and Students Publications

Research on children's technology and digital media (TDM) is hampered by a lack of robust approaches for assessing TDM use. This study assessed the feasibility of passively measuring children's TV screens and mobile devices (TDM) in a naturalistic setting. In the three-day feasibility study, FLASH-TV was set up on one to two TVs the child (5-12 year olds) typically used in the home (n=20). Children's mobile device use was assessed with either the Chronicle App or ScreenTime screenshots. Parents completed three TDM diaries. An exit interview with the parent explored their perceptions of the assessments and the child's TDM use …

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Silent Threats: Awareness And Attitudes To Communication Of Sudep Among Neurologists In India: A Cross-Sectional Study, Rohit Shankar Jul 2025

Silent Threats: Awareness And Attitudes To Communication Of Sudep Among Neurologists In India: A Cross-Sectional Study, Rohit Shankar

Peninsula Medical School

Background: International guidelines unequivocally endorse the importance and need to discuss Sudden Unexpected Death in Epilepsy (SUDEP) with people with epilepsy (PWE). India is a country accounting for a sixth of all global epilepsy burden. Despite this little is known of Indian neurologists’ knowledge and attitudes to SUDEP. Objective: To explore India Neurologists awareness and attitudes to SUDEP communication to PWE. Methods: A cross-sectional online survey of Likert response questions using validated themes, was circulated among the neurology fraternity, India. Non-discriminatory exponential snowballing technique leading to convenience non-probability sampling was used. The inquiry involved SUDEP-related topics including the awareness, knowledge, …

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Differential Roles Of Cyclin–Cdk1 Complexes In Cell Migration And Invasion, Joseph H.R. Hetmanski, Michael J. Jones, Matthew Hartshorn, Patrick T. Caswell, Matthew C. Jones Jul 2025

Differential Roles Of Cyclin–Cdk1 Complexes In Cell Migration And Invasion, Joseph H.R. Hetmanski, Michael J. Jones, Matthew Hartshorn, Patrick T. Caswell, Matthew C. Jones

Peninsula Medical School

We have previously described a central role for CDK1 at the nexus of adhesion signalling and cell cycle progression, demonstrating that CDK1 has a non-canonical role in regulating integrin adhesion complexes and in the migration of cancer cells in 3D interstitial matrix. Here, we show that the CDK1-binding partners cyclinB1 and cyclinA2 also have roles in cell migration and invasion in both cancer and non-transformed cells. CyclinB1 plays a key role in RhoA activation to promote rear retraction in a membrane tension-dependent manner, whereas cyclinA2 has a general role in promoting motility. Knockdown of either cyclin significantly perturbs migration with …

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Defining Economic And Environmental Typologies Across 77 Countries To Prioritize Opportunities For Nonsewered Sanitation, Hannah A. C. Lohman, Yalin Li, Xinyi Zhang, Victoria L. Morgan, Shion Watabe, Stetson Rowles, Roland D. Cusick, Jeremy S. Guest Jul 2025

Defining Economic And Environmental Typologies Across 77 Countries To Prioritize Opportunities For Nonsewered Sanitation, Hannah A. C. Lohman, Yalin Li, Xinyi Zhang, Victoria L. Morgan, Shion Watabe, Stetson Rowles, Roland D. Cusick, Jeremy S. Guest

Civil Engineering & Construction: Faculty Publications

Lack of access to sanitation is a challenge that persists globally, with low sewerage connection rates in many low- and lower-middle-income countries. Engineered nonsewered sanitation (NSS) technologies can meet treatment requirements without sewers, but their relative sustainability varies across potential deployment sites. Here, we characterize the costs and carbon intensity (CI) of three emerging NSS technologies, two community reinvented toilets (CRTs) and one Omni Processor (OP), across 77 countries, identify sustainability performance typologies, and map typology prevalence in countries across the globe. Locality-specific factors such as wages, diet, and material costs drive regional variability in NSS costs by up to …

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Qder: Query-Specific Document And Entity Representations For Multi-Vector Document Re-Ranking, Shubham Chatterjee, Jeff Dalton Jul 2025

Qder: Query-Specific Document And Entity Representations For Multi-Vector Document Re-Ranking, Shubham Chatterjee, Jeff Dalton

Computer Science Faculty Research & Creative Works

Neural IR has advanced through two distinct paths: entity-oriented approaches leveraging knowledge graphs and multi-vector models capturing fine-grained semantics. We introduce QDER, a neural re-ranking model that unifies these approaches by integrating knowledge graph semantics into a multi-vector model. QDER's key innovation lies in its modeling of query-document relationships: rather than computing similarity scores on aggregated embeddings, we maintain individual token and entity representations throughout the ranking process, performing aggregation only at the final scoring stage-an approach we call "late aggregation." We first transform these fine-grained representations through learned attention patterns, then apply carefully chosen mathematical operations for precise matches. …

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Digital Technology Usage In Tajikistan, Siyovush Bobokhonov Dr., Pedro Quelhas Brito Dr., Umesh Ramchandra Raut Dr., Prafulla Arjun Pawar Dr. Jul 2025

Digital Technology Usage In Tajikistan, Siyovush Bobokhonov Dr., Pedro Quelhas Brito Dr., Umesh Ramchandra Raut Dr., Prafulla Arjun Pawar Dr.

The Qualitative Report

The rapid development of digital technologies is significantly changing how people live, and these changes have a particular impact on the younger generation in Tajikistan. Our study therefore aims to analyze the factors influencing young Tajiks' opinions as users of digital technology and to examine digital technology usage in Tajikistan. We conducted a qualitative analysis of the opinions of young Tajik individuals aged 18 to 30 and found that they generally consider digital technology to be an integral part of their daily lives. Data collection was carried out through focus group discussions (FGDs) and the data analysis was performed using …

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Ovochymase 2 Is A Key Regulatory Factor Modulating Proteolytic Pathways And Sperm Maturation In The Mammalian Epididymis, Anna Malovannaya, Thomas X Garcia, Martin M Matzuk Jul 2025

Ovochymase 2 Is A Key Regulatory Factor Modulating Proteolytic Pathways And Sperm Maturation In The Mammalian Epididymis, Anna Malovannaya, Thomas X Garcia, Martin M Matzuk

Faculty, Staff and Students Publications

Spermatozoa acquire fertilizing competence during epididymal transit through proteolytic, chaperone-mediated, and post-translational modifications. Ovochymase 2, an epididymis-specific trypsin-like serine protease, has emerged as a central regulator of this maturation process. Here, we integrate targeted gene disruption, comprehensive proteomic profiling, and affinity-based proteome enrichment to delineate how Ovochymase 2 influences sperm functionality. Deletion of Ovochymase 2 disrupts the proteome of epididymal sperm, resulting in diminished levels of core fertility-related factors-including a disintegrin and metalloprotease domain 3, β-defensins, and protease-inhibitor complexes-while inducing compensatory upregulation of alternate proteases and chaperones. Interaction assays confirm direct or indirect associations between Ovochymase 2 and sperm surface …

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A Mouse Model Engineered To Spatiotemporally Control Cre Expression In Progesterone Receptor Positive Cells†, Artiom Gruzdev, David Cunefare, Charan Ganta, San-Pin Wu, John P Lydon, Francesco J Demayo Jul 2025

A Mouse Model Engineered To Spatiotemporally Control Cre Expression In Progesterone Receptor Positive Cells†, Artiom Gruzdev, David Cunefare, Charan Ganta, San-Pin Wu, John P Lydon, Francesco J Demayo

Faculty, Staff and Students Publications

The Cre/loxP system is widely used for site-specific genetic manipulation in mice. The PgrCre mouse model, where Cre recombinase is driven by the progesterone receptor promoter, is commonly used for gene ablation in Pgr-positive uterine cells. However, the PgrCre is active in the neonatal uterus and does not allow temporal control. To enhance the functionality of the PgrCre mouse, we generated and characterized an inducible PgriCreERT2 mouse, in which iCreERT2 is inserted downstream of the endogenous Pgr promoter. PgriCreERT2 mice crossed with Rosa26-CAG-LSL-Sun1-sfGFP-myc reporter mice demonstrated tamoxifen-dependent recombination in uterine stromal fibroblasts and a subset of epithelial cells. Tamoxifen-induced ablation …

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Bioactivity Of The Synthesized Mgo Nanomaterial By Hydrothermal Technique, Reem Saadi Khaleel, Sabah H. Jumaah, Mustafa Shakir Hashim Jul 2025

Bioactivity Of The Synthesized Mgo Nanomaterial By Hydrothermal Technique, Reem Saadi Khaleel, Sabah H. Jumaah, Mustafa Shakir Hashim

Al-Bahir

MgO was synthesized using the hydrothermal technique. The autoclave containing material based on magnesium (NO3)2.6H2O was filled and heated to 100°C for three hours. Electrophoretic deposition technique was utilized to deposit MgO powder on a Ti plate. To examine its bioactivity (formation of hydroxyapatite (HAp), coated Ti with MgO was then submerged in concentrated SBF for a month. The formation of pure HAp without additional phases including calcium and phosphorus was confirmed by the XRD test. Scanning electron microscope (SEM) images refer to the formation of semispherical HAp nanoparticles with a diameter ≈ 20 …

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Understanding Humorous Contradictions In Comics: A Multi-Agent Debate Approach, Suparna Das Jul 2025

Understanding Humorous Contradictions In Comics: A Multi-Agent Debate Approach, Suparna Das

Master’s Dissertations

Recent advancements in large language models (LLMs) have demonstrated impressive reasoning capabilities, yet their ability to understand and generate nuanced humor—particularly in contexts involving juxtaposition and contradictory narratives—remains a significant challenge. This thesis explores the application of advanced reasoning techniques, specifically multi-agent debate, to enhance LLMs’ performance in understanding and interpreting humor derived from juxtaposed comic panels. . Leveraging the YesBut benchmark—a dataset designed to evaluate AI models on tasks ranging from literal description generation to deep narrative reasoning, we explore how multi-agent debate can address key limitations in current models, such as visual misinterpretation, reasoning gaps, and hallucination. By …

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Cultural Humility, Holistic Admission Review, And Multicultural Experiences Among Newly Admitted Nursing Students, Janna Michelle Hackett Jul 2025

Cultural Humility, Holistic Admission Review, And Multicultural Experiences Among Newly Admitted Nursing Students, Janna Michelle Hackett

Nursing ETDs

This study explored the impact of Holistic Admissions Review (HAR) on demographic characteristics, multicultural experiences, and cultural humility (CH) levels among newly admitted pre-licensure nursing students. Fostering CH and diversity among healthcare providers may help reduce health disparities. Traditional admissions methods may not identify candidates with traits supporting CH development, whereas HAR considers diverse backgrounds and experiences. Two groups were surveyed: one admitted through HAR and the other through traditional methods. No significant differences in CH scores were found, but significant differences were found in age, living abroad, and volunteering with diverse populations. Students admitted through HAR were younger and …

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Low Entropy Side-Channel Secure Hardware Implementations, Jhelum Dhar Jul 2025

Low Entropy Side-Channel Secure Hardware Implementations, Jhelum Dhar

Master’s Dissertations

The demand for symmetric-key cryptography implemented in hardware is growing due to the increasing need for faster, more efficient, and secure encryption in small devices. However, implementing block ciphers in hardware that are side-channel secure remains a challenging goal. This holds true because there exist sophisticated but well-studied attacks such as Differential Power Analysis, which uses the correlation between power consumption of a device and the information on it to allow attackers with physical access to the cryptographic device to get information about secret data. Masking is one of the techniques that is used to provide security against sidechannel attacks. …

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Location Selection Of Migrating Beetles Under Neutrosophic Model With Sensitivity And Comparative Analysis, Rabih Sbera, Ahmed A El-Douh, Darin Shafek, Tareef S. Alkellezli Jul 2025

Location Selection Of Migrating Beetles Under Neutrosophic Model With Sensitivity And Comparative Analysis, Rabih Sbera, Ahmed A El-Douh, Darin Shafek, Tareef S. Alkellezli

Neutrosophic Systems with Applications

Location Selection of Migrating Beetles has different criteria to select the best location. So, multi-criteria decision making (MCDM) is used to deal with different and numerous criteria in this study. This study proposes an MCDM methodology to rank the locations and select the best criterion. The average method is used to compute the criteria weights. The locations are ranked using the root assessment method (RAM). This study uses eight criteria and 20 locations. We use the single valued neutrosophic numbers (SVNNs) to overcome uncertainty and vague information. The RAM methodology is used under the SVNNs. The results show that Availability …

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Risk Management Of The Open Data Services Industry In Digital Transformation Under Neutrosophic Sets, Fadhl Ehsan Hadi, Mohammed Musa Mohammed, Noorhan Waleed Abdullah, Baraa Hasan Hadi Jul 2025

Risk Management Of The Open Data Services Industry In Digital Transformation Under Neutrosophic Sets, Fadhl Ehsan Hadi, Mohammed Musa Mohammed, Noorhan Waleed Abdullah, Baraa Hasan Hadi

Neutrosophic Systems with Applications

The open data services industry is very important for artificial intelligence and digital transformations. The open data services industry has different risks and challenges, so this study proposed a multi-criteria decision making (MCDM) approach for risk management in open data services industry. This study uses the average method to compute the criteria weights and the WASPAS method to rank the alternatives. The triangular neutrosophic set (TNS) is used in this study to overcome uncertainty and vague information. It has three membership functions such as truth, indeterminacy, and falsity. This study uses nine criteria and 18 risks to be evaluated. The …

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Type-2 Neutrosophic Set With Mcdm Methodology For Fire Safety Estimation In Healthcare Services, Eman Sayed Jul 2025

Type-2 Neutrosophic Set With Mcdm Methodology For Fire Safety Estimation In Healthcare Services, Eman Sayed

Neutrosophic Systems with Applications

Fire safety represents a critical priority in healthcare facilities, where complex infrastructures and the vulnerability of patients present significant challenges to evacuation and emergency response. Traditional fire risk assessment methods often fall short in addressing the linguistic variability, uncertainty, inconsistency, and indeterminacy inherent in expert evaluations. While fuzzy and Neutrosophic approaches have been applied in broader healthcare decision-making contexts, no existing study has utilized Type-2 Neutrosophic Numbers Sets (T2NNs) for prioritizing hospital departments based on fire risk. To address this gap, this study introduces a novel multi-criteria decision-making (MCDM) framework that integrates T2NNs for expert modeling, the Entropy method for …

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Type-2 Neutrosophic Numbers For Artificial Intelligence Software Choice For Cybersecurity Testing, O.M. Akash, We’Am Adel Talafha, Mamdouh Gomaa Jul 2025

Type-2 Neutrosophic Numbers For Artificial Intelligence Software Choice For Cybersecurity Testing, O.M. Akash, We’Am Adel Talafha, Mamdouh Gomaa

Neutrosophic Systems with Applications

The choice of artificial intelligence (AI) software for cybersecurity testing is a multi-criteria decision-making approach (MCDM) due to it including different criteria. Evaluation decision making problems include uncertainty and vague information. So, the neutrosophic set is used in this study to overcome this uncertainty and vague information. It has three functions such as truth, indeterminacy, and falsity functions. Type-2 neutrosophic numbers is a type of neutrosophic set that includes nine membership functions. This study uses the average method of computing the criteria weights. The CoCoSo method is used to rank alternatives. Six experts and decision makers created the decision makers …

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Neutrosophic Numbers For Selection Best Strategy For Dual Supply Chains With Green And Non-Green Products, Nada A. Nabeeh, Waleed Abd Elkhalik, Gawaher Soliman Hussein Jul 2025

Neutrosophic Numbers For Selection Best Strategy For Dual Supply Chains With Green And Non-Green Products, Nada A. Nabeeh, Waleed Abd Elkhalik, Gawaher Soliman Hussein

Neutrosophic Systems with Applications

Dual supply chains with green and non-green products are an important aspect of supply chain management, which enable companies to balance traditional operations with ethical and eco-friendly practices to reduce carbon emissions. This study proposed a novel approach that combines the Probabilistic Simplified Neutrosophic Set (PSNS) with the Ranking of Alternatives Method (RAM) for the selection of best strategy selection for dual supply chains with green and non-green products. The novel approach uses PSNS as a representation of uncertainty, by incorporating probabilistic degrees of truth, indeterminacy, and falsity, which occurred in real life situations. Furthermore, RAM illustrates efficient ranking and …

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Pd-Based Hydrogen Separation Membranes Synthesized Via A Liquid-Phase Route, Chase W. Thompson Jul 2025

Pd-Based Hydrogen Separation Membranes Synthesized Via A Liquid-Phase Route, Chase W. Thompson

Chemical and Biological Engineering ETDs

Palladium (Pd) membranes have gained significant attention for their ability to selectively separate hydrogen, a critical process for clean energy applications such as fuel cells and hydrogen storage. However, challenges such as grain growth, sintering, hydrogen embrittlement, and film uniformity limit their scalability and long-term stability. This thesis focuses on the controlled synthesis, deposition, and stability of Pd nanoparticles to optimize membrane performance for hydrogen separation. This work investigates solution-phase synthesis of Pd nanoparticles, focusing on temperature, precursor concentration, and solvent composition as key variables influencing particle growth and dispersion. Pd membranes were fabricated using nanoparticle deposition onto porous supports, …

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Low Temperature Methane Coupling With Co And Co2, A K M Kazi F.M. Aurnob Jul 2025

Low Temperature Methane Coupling With Co And Co2, A K M Kazi F.M. Aurnob

LSU Doctoral Dissertations

Methane is the smallest hydrocarbon and the most abundant component in natural gas. Despite its availability, its chemical utilization has remained limited due to the challenges associated with direct methane activation and conversion. Most of the methane oxidation and oxidative carbonylation reactions in literature have been carried out at high-pressure using batch reactors or at ambient pressure using flow reactors. While batch reactors have been shown to have higher product yields, they are limited in their capability to provide real-time kinetic insights and comprehensive mechanistic understanding of the reactions involved due to the long residence time. This limits rationalization of …

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Book Review: Building A God, Carl Lee Tolbert Jul 2025

Book Review: Building A God, Carl Lee Tolbert

The Journal of Values-Based Leadership

No abstract provided.

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Two Stories Of Management And Two Key Lessons, Mostafa Sayyadi, Michael J. Provitera Jul 2025

Two Stories Of Management And Two Key Lessons, Mostafa Sayyadi, Michael J. Provitera

The Journal of Values-Based Leadership

No abstract provided.

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Raised Colorblind, Still Colorblind, Ritch Eich Jul 2025

Raised Colorblind, Still Colorblind, Ritch Eich

The Journal of Values-Based Leadership

No abstract provided.

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Leadership In The Accountability Era: Resisting Values Drift Through Deliberate System Design, Christine Haskell Jul 2025

Leadership In The Accountability Era: Resisting Values Drift Through Deliberate System Design, Christine Haskell

The Journal of Values-Based Leadership

This study introduces values drift— the gradual, often unconscious misalignment between actions and stated commitments, driven less by misconduct than by lack of awareness, inertia, or performance pressure. As an emerging leadership risk, values drift is increasingly amplified by algorithmic influence and efficiency metrics. This research extends the Values Lifecycle Framework to examine how leaders sustain values alignment in high-velocity, data-driven environments. Through qualitative interviews with 19 CEOs, three leadership typologies emerged: Defaulters, who maintain stability through routine; Correctors, who stand at pivotal choice points where recognition and response are possible but not guaranteed; and Balancers, who embed …

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