Digital Commons Network^™

Vaccine And Treatment Evaluation Units: A Historical Perspective, Robert B Belshe, David I Bernstein, Kathryn M Edwards, Sharon E Frey, Wendy A Keitel, Myron M Levine, John J Treanor, Peter F Wright

Faculty, Staff and Students Publications

On 27 February 1962, Surgeon General Luther Terry announced a new vaccine development program within the National Institute of Allergy and Infectious Diseases (NIAID). Initially, the plan had three components: (1) special laboratories and facilities for development of prototype vaccines; (2) pilot lot production facilities and preliminary vaccine trial sites; and (3) larger lot production capacity and expanded human testing. Respiratory viruses were targeted as the top priority for vaccine development. Over 5 decades, this program has evolved and expanded to include multiple academic vaccine evaluation sites within the network, now labeled as the Vaccine and Treatment Evaluation Units (VTEUs). …

Integrated Magnet, Electron Beam, And Ultrafast Laser Studies For Accelerator Applications, J. K. Chavez, V. Vladutescu, M. Polyanskiy, W. Li, V. Teotia, M. Babzien, D. Choge, M. Palmer, T. Zhao, B. Palencia, J. Rukaj, T. Rahman, M. Islam, O. Situ, L. Geng, L. Leng, G. Ossola

Publications and Research

This study provides an integrated overview of key accelerator technologies explored at Brookhaven National Laboratory: superconducting magnets, ultrafast electron diffraction, and ultrafast high-power lasers. At the Superconducting Magnets Division, dipole and quadrupole magnets were designed using Simulia OPERA and Rat-GUI, with simulations validated through 3D-printed coil testing. These magnets were later applied in the Ultrafast Electron Diffraction facility, where General Particle Tracer (GPT) simulations and real experiments with solenoids, dipoles, and quadrupoles revealed consistent particle beam behavior. At the Accelerator Test Facility, ultrafast lasers were used to generate and manipulate electron pulses. Laser setups were simulated in 3DOptix, then assembled …

Development Of Students Worksheet Based On Project-Based Learning To Train Critical Thinking Skills At Vocational High School, Dia Ayu Permatasari, Harun Nasruddin

Jurnal Pendidikan Sains

Critical thinking is a cognitive skill that helps identify problems and generate solutions, leading to logical decisions or considerations for solving those problems. Students' critical thinking skills can be trained through learning activities to further improve students' critical thinking skills with learning tools. Therefore, this research intends to produce a student worksheet based on project-based learning to train students' critical thinking skills on the colligative properties of solutions. The development research uses the 4D development model from Thiagarajan, limited to the development stage. A limited trial was conducted with 30 students of industrial chemical engineering expertise at Vocational High School …

Problem-Based Learning Assisted By Augmented Reality On The Respiratory System Topic: A Study Of Students’ Critical Thinking Skills And Learning Motivation, Nyimas Dilviana, Ade Yeti Nuryantini, Sumiyati Sa'adah

Jurnal Pendidikan Sains

This study aims to examine the effectiveness of the Problem-Based Learning (PBL) model assisted by Augmented Reality (AR) technology regarding the respiratory system in improving students’ critical thinking skills and learning motivation. The research method used was a quasi-experimental design with a one-group pretest-posttest model. The subjects were 30 eleventh-grade students from a public high school in Garut City. Research instruments included a critical thinking test and a learning motivation questionnaire. The results showed a significant improvement in students’ critical thinking scores after the implementation of PBL with AR support. Additionally, learning motivation data analyzed from 16 statement items revealed …

Lessons Learned: Grahame Johnson, Mercedes Cardona

Journal of Financial Crises

Grahame Johnson was named managing director of financial stability at the Bank of Canada in November 2019, just months before the outbreak of the COVID-19 pandemic, and became adviser to the governor in 2021. The Bank of Canada responded to the economic effect of the pandemic by launching 10 liquidity facilities—nine of them never attempted before—to repurchase securities such as government and corporate bonds, bank acceptances, and commercial paper. The measures were largely successful, and nine of the 10 facilities were unwound by 2022. The tenth, the Government of Canada Bond Purchase Program (GBPP), transitioned into a quantitative easing program …

2017 - Appalachian Student Research Forum Program Booklet, Appalachian Student Research Forum, East Tennessee State University

Appalachian Student Research Forum

No abstract provided.

2016 - Appalachian Student Research Forum Program Booklet, Appalachian Student Research Forum, East Tennessee State University

Appalachian Student Research Forum

No abstract provided.

2015 - Appalachian Student Research Forum Program Booklet, Appalachian Student Research Forum, East Tennessee State University

Appalachian Student Research Forum

No abstract provided.

2014 - Appalachian Student Research Forum Program Booklet, Appalachian Student Research Forum, East Tennessee State University

Appalachian Student Research Forum

No abstract provided.

2013 - Appalachian Student Research Forum Program Booklet, Appalachian Student Research Forum, East Tennessee State University

Appalachian Student Research Forum

No abstract provided.

2011 - Appalachian Student Research Forum Program Booklet, Appalachian Student Research Forum, East Tennessee State University

Appalachian Student Research Forum

No abstract provided.

Letting Students Amaze Us: Teaching For Success In A 4th Grade Classroom, William D. Smyth

Virginia English Journal

A look back at a year in a 4th grade classroom with highly motivated students that came about when a former student, now 48 years old, returned home to visit his 4th grade teacher. According to this student, this was the seminal year that launched his engineering career that he now enjoys in Portland, Oregon. And, speaking for others, this was the turning point in his classmates' educational journeys too.

Enabling Vertical Power Delivery In Large Asics And/Or Asic Packages Using Innovative Heatsink Support Structures, Dylan G. Rust-Nguyen, Vvs Narayana Jagarapu, Marshall J. Lise, David K. Owen

Defensive Publications Series

This document introduces a novel method for integrating heatsink mechanical supports into large ASIC (Application-Specific Integrated Circuit) designs in a way that does not obstruct vertical power delivery. Vertical power delivery is a method that feeds current directly into the underside of the ASIC through vias. Traditional heatsink support structures use drawbars peripheral to the ASIC, distant from the ASIC’s center. The location of these drawbars necessitates the use of large backing plates, but these large backing plates interfere with vertical power delivery. The technique and apparatus described in this paper reposition the forces applied by heatsink drawbars by positioning …

The Indiana Statesman, October 9, 2025, Indiana State University

Student Newspaper

Homecoming

October 9, 2025, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

Ai In Adipose Imaging: Revolutionizing Visceral Adipose Tissue, Ectopic Fat, And Cardiovascular Risk Assessment, Sneha R. Kandi, Sanjay Rajagopalan, Ian J. Neeland

Faculty Scholarship

Purpose of Review: This review explores the role of artificial intelligence (AI) in visceral adipose tissue (VAT) and ectopic fat imaging. It aims to evaluate how AI may be used to enhance the efficiency and accuracy of cardiovascular disease (CVD) risk assessment. It addresses key questions regarding AI’s capabilities in risk prediction, segmentation, and integration with large volume data for CVD risk assessment. Recent Findings: Recent studies demonstrate that AI, powered by deep learning models, significantly improve VAT and ectopic fat segmentation. AI can also be used to facilitate early detection of cardiometabolic risks and allows integration of imaging with …

Microstructural Evolution And Magnetic Properties Of Spark Plasma Sintered Smco5 And Smco5-Fe Composites, Farhan Ishrak, Michael Lastovich, Fu-Yun Tsai, Charles Perkins Iv, Henri Baldino, Alex Helmer, Sean Rego, Sanoj Karki, Daniel Hedlund, Rajeev Gupta, Tushar Borkar

Mechanical Engineering Faculty Publications

Optimizing SmCo(5-)based nanocomposites for high-temperature magnetic applications requires balancing coercivity and saturation magnetization, properties often compromised by grain coarsening, oxidation, and secondary phase formation during conventional sintering. This study investigates the microstructural evolution and magnetic properties of SmCo5 and SmCo5-Fe composites processed via high-energy ball milling followed by spark plasma sintering at 900 degrees C and 1000 degrees C, a route designed to retain the nanostructure while enabling rapid densification compared to conventional sintering. A suite of characterization techniques, including electron microscopy, X-ray diffraction, magnetometry, Magneto-optical Kerr effect, and magnetic force microscopy, reveals the extent of consolidation, phase composition, and …

Role Of Social Comparison Orientation On Financial Management Behavior In A Developing Nation: Examining The Mediating Role Of Financial Self-Efficacy And The Moderating Effect Of Financial Socialization, Afm Jalal Ahamed, Yam B. Limbu

Department of Marketing Faculty Scholarship and Creative Works

Purpose – This study aims to explore the impact of social comparison orientation (SCO) on financial management behavior (FMB) in a developing country with a collectivist culture. It examines how SCO is related to FMB directly and through financial self-efficacy (FSE) and how financial socialization (FS) moderates the SCO–FMB relationship. Design/methodology/approach – Data was collected from 301 adults in Dhaka, Bangladesh, using self-administered survey questionnaires. Mediation and moderation analyses were performed using Smart PLS software. Findings – The results indicate that SCO was positively associated with FMB. FSE mediates this relationship, enhancing SCO’s positive impact on FMB. Additionally, FS moderates …

Holy Cross Magazine, Vol. 59, No. 3, Fall 2025, College Of The Holy Cross

Holy Cross Magazine

Frank Kartheiser ’72 is Comfortable With Your Discomfort
The community organizer and co-founder of the Mustard Seed soup kitchen and food pantry has been feeding the poor and clothing the hungry of Worcester for more than 50 years. His greatest dream is that it closes, yet the need continues to grow.
Story by Marybeth Reilly-McGreen ’89
Photography by Caroline Axvig

The Catholic Church’s Best Kept Secret
Rooted in Scripture and the Church's understanding of human dignity, Catholic Social Teaching helps people live out their faith in the world.
Story by Marybeth Reilly-McGreen ’89
Photography by Michael Ivins

Working to Get …

Interview With Orca Award Winner Donald Weeks; Unl Biochemistry; Biotechnology, Mark Griep, Donald Weeks

UNL ORCA Interview Series

Emeritus Professor Donald Paul Weeks was awarded the ORCA in 2014, a year before he retired. He grew up in a small farm south of Terre Haute, Indiana. In his youth, he participated in 4-H programs that must have sparked an interest in science because he earned his bachelor's degree from Purdue University in 1963. Purdue is about 90 miles north of Terre Haute. Don's doctoral work was at the University of Illinois in Champaign-Urbana for a project about protein synthesis during maize germination. Next, he did postdoctoral work at the Fox Chase Cancer Center in Philadelphia, where his research …

Multimodal Reprogramming Of The Tumor Microenvironment By Mmr And Dual Checkpoint Blockade In Hepatocellular Carcinoma Models, Mulu Z. Tesfay, Aleksandra Cios, Khandoker Usran Ferdous, Randal S. Shelton, Bahaa Mustafa, Camila C. Simoes, Murat Gokden, Isabelle R. Miousse, Kimberly J. Krager, Marjan Boerma, Alicja Urbaniak, Anuradha Kunthur, Sri Obulareddy, Joshua M. Eichhorn, Steven R. Post, Jean Christopher Chamcheu, Omeed Moaven, Chiswili Y. Chabu, Dan G. Duda, Matteo Conti, Bruno Nardo, Rang Govindarajan, Martin E. Fernandez-Zapico, Lewis R. Roberts, Mitesh J. Borad, Martin J. Cannon, Alexei G. Basnakian, Bolni M. Nagalo

Faculty Publications

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related death worldwide, thus, there is an urgent need to develop more effective therapeutic options for this dismal condition. Tumor-infiltrating lymphocytes (TILs) are associated with improved response to immune checkpoint blockade in HCC, but their low abundance in most cases limits their therapeutic efficacy. Here, we demonstrate, in mice, that low-dose intratumoral immunovirotherapy with the trivalent measles, mumps, and rubella vaccine (MMR) induces superior tumor-growth delay and extended host survival compared to individually administered vaccines for measles, mumps, or rubella viruses. Further, our results show that MMR therapy synergizes with PD-1 and …

Incorporating The Influence Of Vehicle Mix On Crash Frequency And Severity, Shahrior Pervaz, Manmohan Joshi, Tanmoy Bhowmik, Dewan Ashraful Parvez, Kai Wang, John N. Ivan, Naveen Eluru

Civil and Environmental Engineering Faculty Publications and Presentations

The current approaches for crash frequency and severity prediction in the Highway Safety Manual (HSM) do not employ vehicle mix information. In this research effort, we build advanced alternatives to HSM methods while incorporating vehicle mix information. Two model systems—(a) multivariate Poisson-lognormal model and (b) negative binomial-ordered probit fractional split model—are estimated by incorporating vehicle mix variables. The developed model systems can also capture the influence of observed and unobserved heterogeneity of different independent variables including vehicle mix variables. We estimate the models for three facility types including Urban Arterial 4-Lane Divided segments, Rural 3-Leg STOP-Controlled and Rural 4-Leg STOP-Controlled …

Pawns In The Power Struggle: Navigating Creative Labor Precarity Across Mcns, Platforms, And State Regulation In China, Qingyue Sun

Interdisciplinary Studies

This study examines how digital creators navigate the precarious Chinese digital creative industries (DCCIs), shaped by multi-channel networks (MCNs), platform logic, and intensifying state intervention. Drawing on interviews with 34 creators, I identified three challenges facing Chinese creators: (1) dual exploitation by volatile platforms and capricious MCN management; (2) erosion of creative autonomy under MCN gatekeeping and state oversight; (3) involuntarily being enlisted as propaganda artisans. Creators, especially those affiliated with MCNs, are increasingly positioned as state labor with governed creativity: cultural workers whose output is shaped, constrained, and redirected by the layered imperatives of state mandates, platform governance, and …

Day-Night Shifts In Water-Soluble Ions Of Size-Resolved Aerosols Before And After The Covid-19 Lockdown In A Coastal Megacity: Metro Manila, Philippines, Grace Betito, Paola Angela Bañaga, Rachel A. Braun, Maria Obiminda Cambaliza, Melliza Templonuevo Cruz, Alexander B. Macdonald, James Bernard Simpas, Connor Stahl, Armin Sooroshian

SOSE Affiliate: Manila Observatory

The COVID-19 pandemic-driven lockdowns offer a unique opportunity to examine how reductions in anthropogenic emissions impacted atmospheric aerosol composition in urban environments. This study investigates the day-night variability of size-resolved water-soluble ions in ambient particulate matter (PM) collected in Metro Manila before (November 2019–February 2020) and after (November 2020–February 2021) lockdown implementation. Using tandem Micro-Orifice Uniform Deposit Impactors (MOUDIs), aerosol samples were collected during daytime (06:00–18:00) and nighttime (18:00–06:00) periods and analyzed for key ionic species (sulfate, ammonium, nitrate, oxalate, sodium, chloride, calcium, and magnesium) via ion chromatography. Submicrometer water-soluble mass declined post-lockdown, particularly during daytime, reflecting suppressed secondary formation …

Special Education Teachers’ Perceptions Of Teaching Effectiveness When Working With Students With Emotional And Behavioral Disorders, Ernest J. Fruge

Walden Dissertations and Doctoral Studies

This qualitative study examined how special education teachers perceived their teaching effectiveness in supporting students identified with emotional and behavioral disorders (EBD). The study addressed a gap in the literature by examining the factors that influence special educators’ sense of self-efficacy when working with this population. Bandura’s theory of self-efficacy served as the conceptual framework. A generic qualitative research design was employed, and data were collected through semi-structured interviews with eight participants from two central Texas school districts. Braun and Clarke’s thematic analysis guided the coding and interpretation process, supported by MAXQDA software. Analysis of the data revealed seven key …

A Meta-Narrative Of Consumer Journeys In Access-Based Consumption: A Case Of Fashion Rentals, Swapnil Saravade, Mohammad Ali Zolfagharian, Reto Felix, Lorena Garcia Ramon, Jacob Almaguer, Hazel Husne Dadanlar

Marketing Faculty Publications

Purpose – The current research aims to identify a meta-narrative that depicts a big picture of the consumer journey with access-based consumption (ABC). Specifically, this research reveals the points of engagement and disengagement with ABC, as well as the transitions between them.

Design/methodology/approach – A qualitative research methodology is applied wherein online reviews and blogs pertaining to Rent the Runway (RTR), an access-based fashion company that enables consumers to rent designer dresses and accessories, are analyzed. Specifically, individual textual narratives of users’ experiences with RTR are analyzed, and a meta-narrative is identified that depicts an overarching story of the …

National Publication Recognizes Um Chemist As Trailblazer, Clara Turnage

University of Mississippi News

OXFORD, Miss. – A news magazine published by the American Chemical Society has selected University of Mississippi chemist Eden Tanner as one of its 2025 Trailblazers, which recognize the contributions of disabled chemists in science, technology, engineering and mathematics fields.

Designing Invisibility: How Hostile Architecture Impacts People Living With Disabilities, Priscilla A. Okolie

The Scholar: St. Mary's Law Review on Race and Social Justice

This comment discusses the potentially unethical and unlawful nature of hostile architecture. This comment posits that hostile architecture is inherently illegal by way of implicitly and overtly violating the Americans with Disabilities Act. This comment argues that hostile architecture violates the ADA because it potentially discriminates against people living with disabilities by hindering their ability to utilize both public and private facilities such as bus stops. This comment acknowledges that while hostile architecture is often used as a tool to discourage unhoused people from using such facilities, hostile architecture also potentially discriminates against people living with disabilities. This comment highlights …

Experiences Of Medically Discharged Veterans Who Transitioned Without A Medically-Oriented Transition Program, Roschelle J. Brown

Walden Dissertations and Doctoral Studies

All discharged service members are required to attend a Transition Assistance Program (TAP). Service members who are found medically unfit to serve must attend TAP prior to being discharged by a Medical Evaluation Board (MEB). This qualitative research study examined the experiences of disabled veterans who were medically discharged with only the general transition program. The problem that was addressed was the lack of information about the experiences of medically discharged service members and the unique challenges that disabled veterans continue to experience because of it. The purpose of this study was to understand the experiences of medically discharged veterans …

Reference At A Remote Field Station: A Case Study Of Ecology, Environmental Science And Geology Fieldwork At An Embedded Library, Thomas Gerrish

Libraries Faculty and Staff Scholarship and Research

Purpose Field station libraries, particularly those serving biological and marine research stations, represent a unique but understudied class of special libraries. This case study investigates reference services at the remote University of Michigan Biological Station (UMBS) to provide a baseline assessment of how such services support the information needs related to research in ecology, geology and environmental science.

Design/methodology/approach The study recorded, coded and analyzed 209 reference transactions from the 2022 and 2023 summer sessions, revealing trends in patron inquiries and the role of the reference desk. Further, the case study examined the organizational structure, community interaction and mission of …