Digital Commons Network^™

A Year In Review On Tuberculosis And Non-Tuberculous Mycobacteria Disease: A 2026 Update For Clinicians And Scientists, Simone Tunesi, Graham Bothamley, Gunar Günther, Yousra Kherabi, Liga Kuksa, Berit Lange, Christoph Lange, Natalie Lorent, Francesca Saluzzo, Martina Sester, Xenia Emilie Sinding Iversen, Marc Tebruegge, Conor Tweed, Anca Vasiliu, Lorenzo Guglielmetti, Tuberculosis Network European Trials Group (Tbnet)

Faculty, Staff and Students Publications

Background: Tuberculosis (TB) remains a major cause of morbidity and mortality worldwide, while infections from non-tuberculous mycobacteria (NTM) represent a growing public health threat. In its 20th year of activity, the Tuberculosis Network European Trials group (TBnet; www.tbnet.eu) is one of the leading research networks in Europe. In this review, we summarize the main advances in TB and NTM that occurred in 2025.

Methods: We conducted a non-systematic review of articles published in 2025, with a strong emphasis on research with current or potential impact on clinical practice. We also selected the most impactful papers regarding the management of adult …

Annual Report Of The Officers Of The Town Of Bartlett, New Hampshire, For The Fiscal Year Ending December 31, 2025, Bartlett Town Representatives

Bartlett, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Annual Report Of The Officers And Committees Of The Town Of Brookline, New Hampshire For Year Ending December 31, 2025, With Reports Of The School Districts For Year Ending June 30, 2025, Brookline Town Representatives

Brookline, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Phase 1 Trial Of Withania Somnifera Leaf Extract (Rh324) In Advanced Non-Small Cell Lung Cancer Including [18f]Fdg Pet/Ct As A Short-Term Metabolic Biomarker To Assess Efficacy: A Novel Model For Assessment Of Complimentary Therapies In Early Phase Human Clinical Trials, Jin Uk Heo, Santosh Rao, Herbert B Newton, Afshin Dowlati, Raymond F Muzic, Arash Kardan

Faculty, Staff and Students Publications

Background: Withania somnifera (WS), commonly known as ashwagandha, has been used in the traditional medical system of India. It has shown significant activity against numerous solid tumor varieties in pre-clinical in vitro and in vivo studies. This study focuses on RH324 (ReHeva Biosciences, Columbus, OH), a pharmaceutical-grade formulation derived from WS, which has received FDA allowance for clinical development as a botanical drug in the treatment of cancer.

Methods: A phase 1 open label dose ranging study of oral RH324 in advanced non-small cell lung cancer (NSCLC) was conducted. The primary endpoint of the study was assessment of short-term safety …

The All Of Us Evenings With Genetics Research Program, Stacy M Lloyd, Jasmine Baker, Carolina Jorgez, Julie Coleman, Laterrica Williams, April Adams, Ashley Butler, Elizabeth Atkinson, Shamika Ketkar, Steven Scherer, Kim Worley, Susan Fernbach, Keasia Daniels, Latanya Hammonds-Odie, Laura Rosales, Brendan Lee, Debra Murray

Faculty, Staff and Students Publications

The All of Us Evenings with Genetics (All of Us EwG) Research Program, funded in part by the National Institute of Health’s All of Us Research Program, engages researchers to utilize the All of Us Researcher Workbench to advance precision medicine. The All of Us EwG program has two core aims: (1) address barriers to research productivity for minorities, disadvantaged, and persons with disabilities aspiring to enter STEM fields; and (2) promote the use of the All of Us Researcher Workbench to develop research focused on health equity. To achieve these goals, the program implements three key activities: (1) …

Esr1 Fusions In Breast Cancer: Functions, Mechanisms And Therapeutic Opportunities, Xuxu Gou, Zoya Farooqui, Charles E Foulds

Faculty, Staff and Students Publications

Approximately 70% of all breast cancers are driven by estrogen receptor-alpha (ERα) that binds the predominant circulating female estrogen, 17ꞵ-estradiol (E2). Because of this, drugs collectively termed “endocrine therapy (ET)” that either suppress E2 level or inhibit the activity of ERα have been used as first-line therapy. While initially effective, resistance to ET drugs occurs with subsequent lethal metastasis. The most common genetic alterations are point mutations in the ESR1 gene within the last exon encoding the ligand-binding domain (LBD), resulting in constitutively active ERα proteins. Recently, new oral selective estrogen receptor degraders (SERDs) that effectively target these point mutants …

Evaluating Mesothelin As An Immunotherapeutic Target For Endogenous T Cells, Kiriakos Koukoulias, Ryu Yanagisawa, Alejandro G Torres Chavez, Penelope G Papayanni, Yovana Velazquez, Hyun-Sung Lee, Spyridoula Vasileiou, Ann M Leen

Faculty, Staff and Students Publications

Background: Mesothelin (MSLN) is a GPI-anchored cell surface glycoprotein that is overexpressed in various solid tumors, including mesothelioma, triple-negative breast cancer, colon, ovarian and pancreatic cancer, with restricted normal tissue expression.

Methods: To explore the immunogenicity and immunotherapeutic potential of MSLN to T cells with native receptor specificity, 29 individuals of diverse HLA backgrounds were interrogated for T cell activity against MSLN.

Results: Twenty one (72%) subjects (21/29) mounted a specific T cell response when repetitively challenged with MSLN antigen. Reactive cells were Th1-polarized, polyfunctional, predominantly detected in the CD8+ T cell compartment and cytotoxic toward autologous and MSLN+/HLA-matched tumor …

Hyperscalers In The Heartland: How A Climate-First Framework Can Incentivize Sustainable Data Center Development And Grid Decarbonization, Eli Dotson

Minnesota Journal of Law, Science & Technology

This Note proceeds in three parts. Part II surveys the rise of AI and hyperscale data centers, the technical and legal challenges their loads pose, and the evolving policy landscape, both nationwide and in Minnesota. Part III argues that Minnesota should build on its emerging data center framework in two ways. First, the PUC should institutionalize the framework’s most promising features by setting a “clean energy floor” to ensure that data centers contribute to, rather than prevent, the decarbonization of Minnesota’s grid. Second, the PUC should create an additional “distributed flexibility pathway” by forcing utilities to consider alternative ways of …

Sound Of NangqêN, Jiayue Cecilia Wu

Journal of the Association for Technology in Music Instruction

Tape Piece is part of a series of single-sound-source daydream pieces, where a solitary object or family of objects is repurposed to create an otherworldly soundscape. This work uses tape--masking, scotch, aluminum, packing, and duct--sometimes recognizable, and sometimes heavily processed. The familiar is juxtaposed with the fresh, and what starts out with unrolling and tearing quickly unravels as sounds evocative of gunfire, of bombs and explosions, and of Geiger counters suggesting the downfall of civilization. New creatures emerge throughout, each trying to find their place in a world that has come unglued.

Drawing Noise, Ivan Elezovic

Journal of the Association for Technology in Music Instruction

DRAWING NOISE is a collaboration between a painter, a composer, and a photographer-video artist. The main intention is to further explore the ambient music that painting and drawing produce. The approach of audio is correlated with the sounds of various hand-movements by color pens on textured drywall. The method of making and designing audio and visual documentation of the creation of the wall drawings serve as the raw material for the final video. The audio in the project originates from recorded artistic performance that portrays a series of circle-shape objects in real time. Furthermore, various layers of sounds are added …

An Inclusive Oer Pedagogy In Teaching Music Technology In Higher Ed, Jiayue Cecilia Wu

Journal of the Association for Technology in Music Instruction

As a Colorado State's Open Educational Resources (OER) funding award recipient, I will present the application of an OER approach in teaching music technology, utilizing free and/or open-source materials, tools, and textbooks/publications. Drawing on two courses I have successfully taught using this methodology, I will highlight practical implementation strategies and their impact. Furthermore, I will introduce national OER funding resources and guide the application process. I will enable music educators to adopt this approach in their teaching practices, enhance their scholarly publications, and secure funding support for academic initiatives.

Tools Of The Trade: An Exploratory Study Analyzing The Frequency And Potency Of Tools In Hip-Hop Music Creation, Performance, And Pedagogy, Drew X. Coles, Cato Zane

Journal of the Association for Technology in Music Instruction

This paper presents findings from a qualitative research study examining the tools most frequently used in the creation, performance, and teaching of hip-hop music. The study collected data from three key stakeholder groups: professional practitioners, music educators, and amateur creators. Through thematic analysis, the research identifies tools ranging from hardware such as MIDI controllers and turntables to software like DAWs and mobile apps, and explores their perceived effectiveness in facilitating musical creativity.

The study’s goal is to inform music educators about the tools that dominate the hip-hop marketplace and their various applications. By understanding how different tools contribute to beat-making, …

It’S Right Behind You!: Sound Object Depth Perception In Modern Horror Film Soundscapes, Nathan Ash-Milby, Timothy Hsu

Journal of the Association for Technology in Music Instruction

This presentation explores the use of spatial sound design within modern horror films, illustrating the efficacy of three-dimensional sound placement techniques on audience immersion within periphonic and binaural speaker configurations. Viewers will learn research-based methods and technical considerations to enhance audience immersion and engagement within spatial horror soundscapes, as well as spatial sound practices that can be utilized within different applications.

Review Of James K. Galbraith And Jing Chen, Entropy Economics: The Living Basis Of Value And Production (The University Of Chicago Press, 2025), Panos Tsoukalis

Emancipations: A Journal of Critical Social Analysis

No abstract provided.

(En)Gendering Capacity: Neoliberalism, Empowerment, And Responsibility For Women In The Un’S Capacity Building Agenda, Sabrina K. Harris

Emancipations: A Journal of Critical Social Analysis

This article analyzes how the UN constructs capacity building as an element of its development agenda. It theorizes that the UN operates as a governmental actor, adopting and pursuing a political rationality of good governance, while also navigating structural limitations to its organizational authority in implementing this agenda imposed by the liberal international order. As such, this article argues capacity building emerges as a valuable technology of development for several reasons: firstly, it operates as an individual-level intervention, circumventing UN limitations on authority in mandating state action, and secondly, it is framed as demand-driven and empowering while delivering on the …

The Present Interregnum: The Ultra-Right Revolution, María Pía Lara

Emancipations: A Journal of Critical Social Analysis

This paper deals with recent political consequences of presentism as conceptualized by the historian Francois Hartog. It clarifies how our experiences of time and history have enlarged the present and the past and have almost disappeared the future (except for catastrophic views). The consequences of these changes in the experiences reflect profound changes in expectations about the future, and how this regime of historicity allows people to become disoriented. They were moved into the margins of precarity. As a result, many of their views on politics find resonance redesigned by the distorted narratives of ultra-right leaders who blame those who …

Case Study: The Economic And Legal Challenges Moving From A Township To A City, George F. Dierberger Dr., Ibrahim Keita Dr., Cory Erickson

Journal of the North American Management Society

The paper examines the economic and legal challenges moving from a township to a municipality in the state of Minnesota. One of the authors was a member of the township board as they went through the process of educating the citizens on the risks and rewards of changing from a township to a municipality.

Maximizing Online Intersession Enrollment Through Targeted Course Offerings, Heather S. Mcmillan, Charles D. Mcallister

Journal of the North American Management Society

Abstract

Online winter intersession courses have become an increasingly important strategy for universities seeking to support accelerated student progression while generating incremental tuition revenue. This study examines ten years of winter intersession enrollment data from a public, master’s-level comprehensive university in the Midwestern United States to identify course characteristics associated with higher student enrollment. Using 12,520 individual enrollment records, the analysis focuses on course type (general education versus major requirement), course classification (lower level, upper level, blended undergraduate/graduate, and graduate), and course discipline. A series of ANOVAs and Bonferroni post-hoc tests reveal significant differences in enrollment across these dimensions, with …

The Top Twenty-Five Most Influential Articles In Surgery For Colorectal Cancer, Dana Poloni, Andrew Anklowitz, Fred Kobylarz, Christina Monaco Poloni, Ankit Dhiman, Pamela Burgess, Andrew Schlussel

HCA Healthcare Journal of Medicine

Background

This article provides surgical trainees with a ranked list of the foundational literature that guides the contemporary surgical management of colorectal cancer and shows the evolution of surgical techniques in the field.

Methods

We assessed the surgical literature using the Web of Science and other ranking systems to create a ranked list of published articles on colorectal cancer surgery.

Results

We compiled a ranked list of the top 25 articles in the surgical management of colorectal cancer, based on the citation density score (mean number of citations per year) and the individual author H-index. The mean density score of …

Integrating Islamic-Based Behavioral Activation With Buya Hamka's Tazkiyatun Nafs To Reduce Social Media-Induced Anxiety Among University Students, Dosi Juliawati, Hengki Yandri, Farid Imam Kholidin, Rasmita Rasmita, Daflaini Daflaini, Yatti Fidya

Buletin Konseling Inovatif

The pervasive use of social media has led to a growing concern regarding social media-induced anxiety among university students. This study aims to integrate Islamic-based Behavioral Activation with the concept of Tazkiyatun Nafs, defined as the purification of the soul or self-purification, as proposed by Buya Hamka, to reduce this anxiety among university students. The method employed is a Single-Subject Experimental Design involving three participants from IAIN Kerinci, all of whom exhibited the highest scores of social media anxiety. Data were collected using the Social Media Anxiety Scale (SMAS) and analyzed through visual data analysis. The results indicate that all …

Peaceful School Counselors For School Violence In The Digital Era, Ahmad Yusuf Sobri, Nur Mega Aris Saputra, Dzulkifli Abdullah

Buletin Konseling Inovatif

The problem of violence that occurs in the world of education is a manifestation of the incomplete realization of schools as safe places. One strategy to make this happen is through the implementation of peace education in schools that involves all school members. School counselors are one of the key roles needed for the implementation of peace education in schools. This study aims to find out the role of school counselors in implementing peace education in schools. The study is a systematic literature review using the PRISMA stages. Fifteen academic articles were selected based on the main keywords: peace education …

The Role Of Personal Responsibility And Career Planning Among Adolescents In Indonesia: A Correlational Study, Irvan Handaka, Denik Wirawati, Aprilia Setyowati, Wahyu Nanda Eka Saputra, Diki Herdiansyah, Navy Glenda Triskova, Zela Septikasari, Norimune Kawai, Rafidah Aga Mohd Jaladin

Buletin Konseling Inovatif

Personal responsibility is an individual's ability to identify and regulate one's thoughts, feelings, and behaviors and the willingness to take responsibility for the choices and resulting social and personal outcomes. Through a quantitative correlational study, this study explores the role of personal responsibility and career planning in high school students/adolescents. A total of 465 adolescent subjects from Indonesia were sampled in this study. The data collection method used instruments tested for validity and reliability in measuring personal responsibility and career planning. Data analysis was conducted using descriptive statistics to describe the level of personal responsibility and career planning and inferential …

Instagram Sebagai Ruang Cyberbullying Untuk Memenuhi Kebutuhan Gaya Hidup Hedonis Siswa Sekolah Menengah Atas, Elcindi Lazuardin Zamzamima, Im Hambali, Rizka Apriani

Buletin Konseling Inovatif

Recently, social media has been an integral part of adolescents’ life, serving as a medium for their self-actualization. On the other hand, adolescents use social media for hostile activities, such as bullying. This study describes Instagram as a platform for cyberbullying as it allows students to demonstrate their hedonist lifestyle. In this study, we used a descriptive qualitative approach. For the data collection, we involved two senior high school students, who were selected through purposive sampling with the criteria of undertaking cyberbullying acts to fulfill their needs for a hedonist lifestyle. The data were collected through structured interviews and documentation. …

Biofilm-Associated Infections: Mechanisms Of Formation, Resistance, And Emerging Therapeutic Strategies With Special Focus On Biofilm Inhibitors, Karem Ibrahem

Journal of King Abdulaziz University: Medical Sciences

Biofilms are complex, structured microbial communities enclosed within a self-produced extracellular matrix. This matrix allows them to adhere to a variety of surfaces, including medical devices and human tissues. The formation of biofilms poses a significant challenge in clinical settings due to their inherent resistance to antibiotics and to host immune defenses, thereby contributing to the persistence and chronicity of infections. In recent years, considerable attention has been directed towards the development of biofilm inhibitors as a promising therapeutic strategy to prevent biofilm formation, disrupt established biofilms, and enhance the susceptibility of biofilm-embedded bacteria to conventional antibiotics. The aim of …

Barriers To Youth Employment And Economic Mobility In The Bronx, David Cortes

CUNY Mexican Studies Institute

This research aims to uncover systemic factors that limit career stability for young adults in the Bronx. In this paper, I focus on unequal access to educational resources, economic inequality, and the digital divide as connected barriers that shape the quality of education and training youth receive, the resources and networks they have access to, and the opportunities they can realistically maintain over time. Based on a review of public data, media reports and the current literature, I argue that job instability in the Bronx is a structural problem. At the same time, this project pushes back against the assumption …

Lost In Ambiguity: Ai And The Limits Of Processing Turkish Morphology, Engin Evrim Önem

Khazar Journal of Humanities and Social Sciences

Despite rapid progress in natural language processing, artificial intelligence (AI) systems continue to struggle with languages characterized by high morphological complexity, such as Turkish. A central difficulty lies in their limited ability to resolve ambiguity, which is deeply embedded in Turkish through features like flexible word order, extensive case marking, and agglutinative structures. Current AI models, primarily shaped by exposure to massive corpora of performance data, excel at detecting surface-level statistical regularities but fall short of grasping the grammatical principles and semantic nuances that underpin genuine linguistic competence. This reliance on performance over competence makes disambiguation especially problematic, as the …

Artificial Intelligence In Higher Education: A Bibliometric And Science-Mapping Analysis From An Institutional And Management Perspective, Kürşat Taştan, Nalan Sabır Taştan

Khazar Journal of Humanities and Social Sciences

This article maps the field of artificial intelligence in higher education (HEI-AI) from an institutional and management perspective. We draw on 52,270 peer-reviewed articles and reviews indexed in Web of Science and Scopus between 1959 and 2025. Using the bibliometrix package and its biblioshiny interface in R, we combine descriptive indicators with science-mapping techniques, including co-authorship and co-citation networks, keyword co-occurrence, thematic mapping and thematic evolution. The initial corpus of 94,845 records was cleaned by merging the two databases, removing duplicates and restricting the sample to full-length journal articles and reviews that explicitly address AI in higher education.

The results …

Getting Started With Research In International Engineering Education, Kirsten A. Davis, Brent Jesiek

Journal of International Engineering Education

No abstract provided.

Feasibility Assessment Of Energy As A Service With Third Party Ownership For Development Of Utility-Scale Solar Pv In The Consumer Goods Industry, Winda Puspadimiati, Widodo W Purwanto

CSID Journal of Infrastructure Development

Global awareness of climate change impacts has compelled the power sector to adopt renewable energy as a primary source of electricity, driving innovation in renewable energy business models. This study analyzes the feasibility of Energy as a Service (EaaS) with a Third-Party Ownership (TPO) scheme for utility-scale solar photovoltaic (PV) development in the fast-moving consumer goods (FMCG) industry. Four scenarios of utility-scale solar PV configurations under the EaaS model are evaluated: on-grid ground-mounted (OG-GM), hybrid ground-mounted (H-GM), on-grid floating (OG-F), and hybrid floating (H-F). All scenarios are developed under the assumption of utilizing the PLN grid through a power wheeling …

Moving From Feasible Solutions To Sustainable Systems In The Built Environment, Mohammed Ali Berawi, Mustika Sari, Perdana Miraj

CSID Journal of Infrastructure Development

The built environment plays a crucial role in global sustainability efforts. Buildings, infrastructure, and cities consume large amounts of energy and materials that shape social behavior, and lock in environmental impacts. Over the past two decades, research has produced a wide range of technical solutions to reduce these impacts. Renewable energy systems, energy-efficient buildings, alternative construction materials, and new construction methods are no longer experimental concepts. Many have proven technical and economic potential. Yet, real-world transformation remains slow and uneven. This gap suggests that sustainability challenges in the built environment are no longer driven by a lack of technology. Instead, …