Digital Commons Network^™

Dna Half-Adder Based Calculator Driven By 4j Molecular Switches, Andrea Gissele Canizalez Covaleda

Honors Undergraduate Theses

DNA nanostructures have computing functions due to the predictable base pairing of nucleic acids (Watson–Crick). This property allows the programming of DNA circuits that integrate DNA logic gates capable of recognizing oligonucleotides. This molecular device offers the advantages of biocompatibility and potential applications in personalized medicine for diagnosis and therapies.

Our lab has developed DNA logic gates formed by the connection of YES strands via DNA four-way junctions (4J), which can function as molecular switches to develop a DNA-based calculator. Our DNA half-adder calculator nanostructure is designed to recognize up to three combinations of DNA inputs using three DNA strands …

Designing Rhetorical Education For Online Audiences, Nicholas Dixon

Honors Undergraduate Theses

This project demonstrates a multimodal education for online audiences through the creation of a YouTube video, What is Rhetoric?   The literature from composition, education, and media asserts that online multimodal media is useful for idea production, civic discussion, and learning. This project follows the idea that online multimodal digital media are valuable forms for meeting audiences with access to rhetorical knowledge, both within academic institutions and in the education of public audiences. In Confronting the Challenges of Participatory Culture, Henry Jenkins highlights the challenge online participants face in recognizing the ways media shapes perceptions of the world (xii). Rhetoric is …

Evaluating The Comparison Of Different Body Locations For Data Collection Using Galvanic Skin Response Of Forensic Chemistry Students When In Lecture And Laboratory Environments, Elisa Guerrero

Honors Undergraduate Theses

Anxiety is the response that humans can have when exposed to a stimulus. It can be caused by a multitude of factors, such as psychological, biological, or physiological stimuli. Anxiety can be presented as a state or as a trait in a person. Trait anxiety is typically seen as a more stable personality trait, whereas state anxiety is a more intense temporary emotional state. In our study, anxiety was regarded as a more state-like characteristic. A galvanic skin response (GSR) Shimmer3+ device can measure skin electro-conductance changes following stimulation. In a situation where a participant is experiencing anxiety, levels of …

Mycoethics: Reverence For Life In Light Of Modern Science, Charis E. Meyers

Honors Undergraduate Theses

There is a 21^st century wave of passion surrounding fungi and mycology, and it’s becoming louder and louder. The mycoenthusiasts themselves have a uniquely inspired ethical system born out of their science, and my aim is to both formally introduce their position, including many unspoken foundations, and defend its potential. I call this position mycoethics and attempt to collect it from the scattered tidbits in mycological media. I first identify its historical precedent, then spend a length of time establishing where its sense of goodness comes from, postulating it as a utilitarian offspring of Albert Schweitzer’s reverence for life. …

Characterizing A Low-Gradient Stream In Central Illinois As Gaining Or Losing And Observing Seasonal Changes In This Behavior, Eric Timothy Brunner

Theses and Dissertations

While the seasonal behaviors of low-gradient streams have been studied, the behavior of surface water and groundwater interactions within low-gradient streams in glaciated terrain is not fully understood. A third order, low-gradient glacial stream with a saturated riparian buffer in central Illinois was studied to determine the direction of flow between the surface water and groundwater. The goals of this study were to determine 1) whether the stream was gaining or losing water, and 2) whether the gaining or losing nature of the stream-aquifer system changes seasonally. At both an upgradient and downgradient location, two wells were installed: one in …

An Application Of Molecular Dynamics To Hed Plasma Physics: Point And Group Defect Diffusion In Coulomb Crystals, Levi Webb

Theses and Dissertations

Molecular dynamics (MD) simulations are used to explore the microscopic behaviors of complex systems that cannot be easily studied experimentally. In particular, the microphysics of high energy density (HED) astrophysical plasma environments remain inaccessible by modern experiment---even in laser facilities, these plasmas exist only on short timescales that do not lend easily to investigation. The diffusion of point and group defects through crystallized plasmas in the cores of white dwarfs and neutron star crusts, called Coulomb crystals, has potentially macroscopic implications for the evolution of these bodies. Thus, I employ the widely-used MD code LAMMPS to simulate small Coulomb crystal …

Examining Explicit Professional Development As A Means To Change Inclusive Mindsets, Mitchell E. Elatkin

Theses and Dissertations

Inclusive education requires educators to hold beliefs that support the participation and success of students with disabilities in general education settings. Although federal policy mandates access to the least restrictive environment, educator attitudes toward inclusion continue to influence the implementation of inclusive practices. The purpose of this mixed-methods study was to examine whether explicit professional development (PD) focused on inclusive mindsets influenced school stakeholders’ attitudes toward inclusion across a school year. Participants included representatives from various roles within a charter school organization in the Midwest. The researcher collected data through two administrations of the Adapted Teacher Attitudes Toward Inclusion Survey …

Performance-Based Funding’S Influence On Higher Education Through The Eyes Of Department Chairs, Jonathan W. Lackland

Theses and Dissertations

Performance-based funding (PBF) has become a widely adopted policy in higher education, linking state appropriations to measurable outcomes such as graduation rates, degree completions, and workforce alignment. While PBF aims to enhance institutional accountability and efficiency, its implementation has raised significant concerns about equity and political influence. This dissertation examines the political equity and implications of PBF policies through a mixed-methods approach, including surveys, interviews with department chairs, and critical discourse analysis of state statutes and legislative debates. The findings reveal that PBF often exacerbates inequities, particularly for non-flagship universities serving diverse and under-resourced student populations. Department chairs expressed concerns …

Evaluating The Role Of Power Electronics In Enhancing Renewable Energy And Smart Grid Performance: A Review, Muhammad Irfan Habib

ASEAN Journal on Science and Technology for Development

The review article demonstrates the importance of power electronics in propelling the increase of renewables and increasing the efficiency of contemporary electrical grids. In particular, it highlights the need for bidirectional converters for effective energy management in vehicle-to-grid (V2G) systems with two-way power transfer. The paper examines the series of complications offered by the significantly large integration of power electronic converter-interfaced renewables, such as those related to system steadiness, power quality, and resignation bottlenecks. Also, it recognizes a mix of new technologies, such as wide bandgap (WBG) semiconductors like silicon carbide (SiC) and gallium nitride (GaN), that deliver superior performance …

Extraction And Characterization Of Fresh And Dehydrated Cactus (Opuntia Ficus Indica) Polysaccharide For Hydrogel Preparation, Aye Thwe Thwesoe, May Myat Khine

ASEAN Journal on Science and Technology for Development

In this research, extraction of polysaccharide compounds from Cactus (Opuntia Ficus Indica) leaves in both fresh and dehydrated condition by solvent precipitation method using three types of water, acid (HCL) and NaOH. Before extraction, the physicochemical properties were examined to determine optimum yield (%) of extracted polysaccharide by optimization of Box-Behnken Design (BBD) of response surface methodology (RSM). The polysaccharide-based acrylamide hydrogel was prepared by free radical polymerization. The functional and structural characterization was done by FTIR, XRD and SEM for examination of extracted polysaccharide as raw polymer backbone in hydrogel preparation and prepared hydrogel as adsorbent for metal removal. …

Unlocking Green Potential In Indonesian Small Medium Enterprises: Challenges And Opportunities For Sustainable Vermicelli Production, Togar W. S. Panjaitan, Karina Agustin, Prayonne Adi, Jani Rahardjo, I Nyoman Sutapa

ASEAN Journal on Science and Technology for Development

Due to limited initiatives and support, the transition to green manufacturing among small and medium enterprises (SMEs) in developing countries remains challenging. Through a critical literature review and case study of the Indonesian vermicelli industry, this study highlights the importance of collaboration and strong policies to address this. Other findings also reveal that the energy intensity and emissions in the sector exceed best practice benchmarks, with the cooking and drying stages contributing significantly to emissions due to high energy consumption. Lack of government regulations, company awareness, and understanding of applicable practices and technologies creates challenges in green manufacturing. The study …

Hybrid Model For Phishing Website Detection Using Transfer Learning, Atul Dubal, Mansi Subhedar, Santosh Dhamala, Manasi Patil

ASEAN Journal on Science and Technology for Development

The rapid digitization of human activities has intensified reliance on internet-based platforms, creating fertile ground for cybercriminal exploits such as phishing. Despite advancements in detection mechanisms, phishing attacks continue to evolve, leveraging sophisticated visual mimicry to deceive users. This paper proposes a robust vision-based phishing detection system using ensemble deep learning to analyse webpage screenshots. The framework integrates transfer learning with pre-trained VGG16 and DenseNet121 models, extracting complementary low-level texture features (edges, gradients) and high-level hierarchical patterns (logos, layouts). These features are fused through a custom classifier with dropout regularization to mitigate overfitting. A balanced dataset of 3,000 webpage screenshots …

Beyond The Binary: Navigating Ai’S Role In Palliative Ethics-A Review, Reebu Sara Varghese, Tijo Cherian

ASEAN Journal on Science and Technology for Development

Palliative care is being influenced by artificial intelligence, especially when it comes to data-related aspects. In this context, care can be enhanced in terms of the quality of its results and the level of its efficiency, particularly with the help of technological tools such as artificial intelligence, which is capable of managing different types of information in the field of health care. Such characteristics have the potential to improve the quality of patient care while at the same time reducing the workload of healthcare professionals in palliative care. However, there are considerable ethical issues that need to be addressed with …

Ai-Assisted Hybrid Ga–Pso Channel Allocation Under 3gpp Tr 38.901 Uma For Efficient 5g Radio Resource Management, Sharada Narsingrao Ohatkar

ASEAN Journal on Science and Technology for Development

The increased traffic and heterogeneity in the 5G/B5G network require efficient radio resource management (RRM). However, the existing methods, such as GA and PSO, have poor convergence speed and require proper initial conditions. Additionally, learning-based methods have high computational complexity. Hence, in this paper, a novel AI-assisted Hybrid Channel Allocation (AI–HCA) framework is proposed by using a support vector regression (SVR)-based predictive initialization method and GA-PSO optimization. Simulation results using the 3GPP UMa channel model show that the proposed method has a 28% reduction in call blocking probability (CBP), a 15-25% enhancement in spectral efficiency (SE), and a 18-25% enhancement …

Assessing The Influence Of Land Use Land Cover Alterations On Climate Variability In Thimphu & Chhukha, Sonam Zangpo, Karma Choki, Tashi Tobgay, Phurpa Rinchen, Tandin Tshewang

ASEAN Journal on Science and Technology for Development

This study examines the spatiotemporal dynamics of land use and land cover (LULC) changes and their influence on local climate variability in Bhutan using an integrated geospatial and machine learning framework. LULC changes during the period 2004 to 2022 were analyzed to understand their relationship with localized climate responses. Despite increasing urbanization pressures, comprehensive assessments linking LULC dynamics with climate variability in Bhutan remain limited. Geographic Information System (GIS) techniques and Random Forest classification were used to map LULC changes, while non-parametric trend analyses (Mann–Kendall test and Sen’s slope estimator) were applied to evaluate trends in key meteorological variables, including …

Understanding Waste Management Knowledge And Habits Of Senior High School Students In Lianga, Surigao Del Sur, Philippines, Arnele Mie A. Fanuga, Romy M. Avila, Reyl Justine J. Ballena

ASEAN Journal on Science and Technology for Development

The effective implementation of Solid Waste Management (SWM) in educational institutions is challenged by increasing student populations, limited infrastructure, and inconsistent policy enforcement. This study assessed the Knowledge, Attitudes, and Practices (KAP) of senior high school students regarding SWM in three secondary schools in Lianga, Surigao del Sur, Philippines. Data were collected using a descriptive-correlational design from 150 students selected through quota sampling. Pearson’s correlation analysis revealed significant associations between knowledge and attitude, and between attitude and practice. Knowledge scores were positively correlated across the three secondary schools. Students demonstrated a high level of awareness of the environmental and health …

Sustainable Conductive Rpla-Carbon Black Filament For Additive Manufacturing Via Single-Screw Extrusion, Zaidan Faraby Zulkarnain, Shakina Hawapi, Aini Zuhra Abdul Kadir, Muhd Ikmal Isyraf Mohd Maulana, Nor Akmal Fadil, Najlaa Nazihah Mas’Ood, Mohd Rizal Alkahari, Saidin Wahab

ASEAN Journal on Science and Technology for Development

The growing demand for low-cost, sustainable conductive filaments for additive manufacturing motivates the exploration of recycled polymer feedstocks as alternatives to virgin materials. However, the effects of prior thermal reprocessing on both the electrical performance and morphological integrity of recycled PLA (rPLA)–carbon black (CB) composite filaments remain insufficiently characterised, particularly under single-screw extrusion conditions. This study fabricates and characterises conductive filaments from virgin PLA and rPLA, each loaded with CB at 0.2, 0.6, and 1.0 wt%, using a low-cost desktop single-screw extruder. Melt blending was found to be essential for achieving continuous filament extrusion, as ball milling produced insufficient filler …

Spectroscopic And Structural Characterization Of Unexpected Porphyrinoid Byproducts Resulting From The Reaction Of A Cyclopentadiene Trialdehyde With N-Alkyltripyrranes, Kimberly Le, Gregory M. Ferrence, Timothy D. Lash

Faculty Publications – Chemistry

Acid-catalyzed condensation of N-alkyltripyrranes with a cyclopentadiene trialdehyde, followed by oxidation with aqueous ferric chloride solutions, gave unusual tripyrrolic byproducts in addition to previously reported carbaporphyrins and oxycarbaporphyrins. These stable nonaromatic structures incorporate aldehyde substituents, macrocyclic ketones, two conjugated pyrrole units, and a pyrrolo[1,2-a]pyrrole moiety. The NMR and UV-vis data were consistent with a nonaromatic system, and single-crystal X-ray diffraction confirmed that these structures are highly distorted. Structural characterization of a related aromatic carbaporphyrin triketone was also accomplished.

A Nuclear Terrorism Scenario: Improvised Nuclear Weapons With 60%-Enriched Uranium, Matt Caplan

Faculty publications – Physics

In this work we show that approximately 60–70 kg of 60%-enriched uranium can be used to build a crude nuclear weapon with a kiloton yield. While too large to fit on a missile, such a weapon could be delivered by a shipping container. This analysis is motivated by the June 2025 Israeli and US attacks on Iran, especially the bombings of the nuclear facilities at Natanz, Fordow and Isfahan. The Iranian stockpile of approximately 440 kg of 60%-enriched uranium is, at the time of writing, inaccessible to IAEA inspectors and stored in secret. The rapid clandestine relocation of this material …

Mr Ma Fung-Kwok, Gbs, Jp 馬逢國先生, Gbs, Jp

Honorary Fellowship 榮譽院士

No abstract provided.

Balancing Nationalities In International Investment Law, Peter J. Spiro

Chicago Journal of International Law

How can you tell where someone is “from”?  Historically, an individual’s national identity was singular, starting with formal nationality. One’s national center of gravity was readily determinable. Not so today. Determining one’s primary national identification is no longer an easy thing in many cases. This is consequentially enabled by the growing acceptance of dual citizenship. One can openly identify as a formal member of more than one country in a way that was disfavored in the past.

International investment law, however, has not caught up to this reality. In an increasing number of international arbitrations, tribunals are shutting the doors …

Artificial Intelligence And Data Science In Agriculture Specialty Crops And Climate Change Modeling, Chandrasekar Vuppalapati

Faculty Research, Scholarly, and Creative Activity

Specialty crops—fruits, vegetables, nuts, horticulture, and nursery crops—are a powerful engine of agricultural growth, contributing nearly one-fifth of U.S. farm revenues and driving a $1.6 trillion global market. As demand rises and climate challenges intensify, growers need smarter tools to stay competitive. This book brings together AI, data science, climate modeling, and economic forecasting to help farmers and innovators improve yields, manage risk, enhance sustainability, and secure long-term profitability. Designed for agricultural leaders, technologists, and policymakers, it delivers practical, future-ready solutions to strengthen specialty crop resilience and global food security. Presents the applications of data science and AI to agriculture …

Empowering Students To Engage With Climate Change Action: A Project-Based Module For Artificial Intelligence Literacy And Sustainability Thinking, Gabriel Granco, Yu Chen, Heather Macias, Yunfei Hou, Frank A. Gomez

Faculty Research, Scholarly, and Creative Activity

There is a growing need to prepare students to address complex environmental challenges, particularly climate change and the expanding role of artificial intelligence (AI). This article examines the adaptation of the Artificial Intelligence for Social Good (AI4SG) Ideation module, a pitch- and project-based teaching framework designed to integrate AI literacy and sustainability education. Implemented in an upper division climate change course, the module combines project-based learning, culturally responsive pedagogy, and geographic thinking to guide students in developing community-oriented AI proposals aligned with the United Nations Sustainable Development Goals (SDGs). Students were encouraged to approach their communities not through deficit lenses, …

Criterion Validity Of The Functional Status And Pain Assessment Scale Versus Pain And Length Of Stay In Hospitalized Adults With Scd, Wally R. Smith, Daniel M. Sop, Yue May Zhang, Margaret S. Guy, Rehan Qayyum

Department of Medicine Faculty Publications

Objectives

In prior research we demonstrated face, construct, discriminant, and preliminary convergent validity of the newly developed, 10-item Functional Status Pain Assessment (FSPA) scale (0-50) in adult SCD patients hospitalized with VOC. We aimed in this study to further demonstrate criterion validity of the FSPA.

Methods

This was a prospective observational study of 561 daily functional and pain assessments from 91 hospitalized adults with SCD from January 2018 to June of 2019. Principal Component Analysis (PCA) Partial Least Squares (PLS) models determined the relationship between LOS, pain intensity, and FSPA. A Generalized Linear Model (GLM) to quantified the impact of …

Antibody-Drug Conjugates Beyond Her2 In Non-Small Cell Lung Cancer (Nsclc): Mechanisms, Emerging Targets, And Future Directions, Ahmed Ismail, Akash Desai, George R. Simon, Yanis Boumber

Department of Medicine Faculty Publications

Antibody–drug conjugates (ADCs) are a rapidly evolving class of oncology therapeutics that enable precise delivery of potent cytotoxic agents to tumor cells while minimizing systemic toxicity. While HER2-targeted ADCs such as trastuzumab deruxtecan (T-DXd) in HER2-mutant, Datopotamab deruxtecan (Dato-Dxd) in EGFR-mutant, and telisotumumab vedotin (Teliso-V) in MET IHC 3+ expressing lung cancer have already established a clinical role in non-small cell lung cancer (NSCLC), multiple ADCs targeting alternative antigens, including additional TROP2 ADCs, HER3, MET, CEACAM5, B7-H3, Nectin-4, and others, are now in advanced clinical development. This review synthesizes the current evidence for non-HER2 ADCs in NSCLC, highlighting mechanisms of …

Dietary Intake Of Micro- And Nanoplastics: Potential Adverse Gi Effects On Microbiome, Inflammation, And Neoplasia, Michael Saadeh, Gordon Hong, Sana Rabeeah, Priyata Dutta, Edward C. Oldfield, Iv, David A. Johnson

Department of Medicine Faculty Publications

Micro- and nanoplastics (MNPs) are pervasive in food-contact environments and the human diet, positioning the gastrointestinal (GI) tract as the primary portal of entry and a plausible site of early biological effects. Human exposure is supported by detection of microplastics in stool and colon tissue, and emerging clinical studies report associations between fecal microplastic burden and GI disease states, including inflammatory bowel disease (IBD) and colorectal cancer (CRC). Preclinical studies provide mechanistic plausibility, reporting that ingested MNPs can modulate microbial ecology, alter mucus membrane integrity, increase intestinal permeability through changes in cellular tight junction biology, and induce inflammatory gene expression. …

Micro- And Nanoplastics: A Paradigm Shift In The Pathogenesis Of Inflammatory Bowel Disease, Michael Saadeh, Priyata Dutta, Gordon Hong, Edward Oldfield, David A. Johnson

Department of Medicine Faculty Publications

Micro- and nanoplastics (MNPs) are pervasive environmental contaminants with growing recognition as potential contributors to human disease. Widespread human exposure occurs primarily through ingestion of contaminated food and water, and MNPs have been detected in multiple human tissues, including the gastrointestinal tract. Experimental evidence provides a plausible biological basis for disease associations, including impairment of intestinal barrier integrity, activation of mucosal immune pathways, and alteration of gut microbial communities caused by MNP exposure. Although human data remain limited, early studies demonstrate MNP detection in stool and suggest potential correlations with inflammatory biomarkers such as fecal calprotectin. These findings, together with …

Regional Pain Is Associated With Functional Performance In People With Parkinson's Disease, Ryan P. Duncan, Monica R. Hendricksen, Luke Ekdahl, Kevin Smaller, Benjamin Friedman, Miriam R. Rafferty

Department of Medicine Faculty Publications

Background and Purpose:

Little is known about how pain influences physical function in people with mild Parkinson disease (PwPD). The purpose of this study was to investigate the association between physical function and pain presence, location, and intensity in PwPD who were evaluated in an early physical therapy program.

Methods:

Retrospective cross-sectional analysis of electronic medical records from patients with PD evaluated at a single center (2016-2023). Pain presence, location, and intensity (0-10 scale) were recorded at the initial physical therapy evaluation. Functional outcomes included 5-time sit-to-stand, 10-meter walk test, 6-minute walk test, timed up and go, mini-BESTest, and Functional …

Microplastics, Nanoplastics, And Obesity: Current Evidence And Biological Mechanisms, Maram Albandak, Sanam Rabeeah, Ahmad Mahdi Zahidi, David A. Johnson

Department of Medicine Faculty Publications

Obesity is a rapidly growing global health concern. The pathogenesis is complex and cannot be fully explained by lifestyle factors alone. The increasing attention towards this concern has finally been directed towards environmental contributors which may influence metabolic regulation. Microplastics and nano-plastics (MNPs) are ubiquitous environmental pollutants that have recently been detected in food, drinking water, air, and human biological samples, raising concerns about their potential role in metabolic disorders, including obesity. Chronic exposure to MNPs may interfere with metabolic homeostasis through multiple biological pathways. Emerging evidence, including both experimental and animal studies, reports alterations in lipid metabolism, body weight, …

Hands-On: Integrating Active Learning Into An Upper Extremity Occupational Therapy Elective, Jennifer Radziak, Katie Jones, Kelsey Picha

Journal of Occupational Therapy Education

In an effort to provide students with advanced clinical practice skills, several occupational therapy elective courses were developed. The current article describes an educational innovation that involved an in-person elective course for graduate second year Master of Science in Occupational Therapy students that focused on the upper extremity. The course was team-taught, promoted active learning, and used unique activities to engage students in the learning process. Relevant evidence-based practice literature and clinical guidelines were incorporated into the course to teach students about the treatment of upper extremity conditions. The active learning strategies implemented in the course included fresh donor dissection, …