Digital Commons Network^™

Prephiral Bacterial Infectious Agent Triggers Neuroinflammatory Responses And Neurobehavioral Impairment In Wild-Type Mice, Hadeer Atalah

Theses and Dissertations

Neurodegenerative diseases, including Alzheimer's and Parkinson's, present an increasing global challenge, with chronic neuroinflammation identified as a principal factor alongside genetic, environmental, and infectious influences (Boyd et al., 2022).  Epidemiological data associate bacterial infections with a 40% heightened risk of Parkinson's disease; however, the mechanisms—especially the direct connection between peripheral sepsis and the silent onset of central nervous system pathology absent acute meningitis—are inadequately investigated (Smeyne et al., 2021), particularly concerning common pathogens like Klebsiella pneumoniae in high-burden areas such as Egyptian ICUs, where it constitutes 30% of cases (Alkompoz et al., 2023). This study filled the gap by creating …

The Impact Of Environmental Communication On Consumer Behavior: The Mediating Role Of Ascription Of Responsibility And Attitude, Nada Hussam El-Maghraby

Theses and Dissertations

The current study aims to examine the effect of environmental communication on promoting pro-environmental behaviors (PEBs) in the Egyptian society. The study also tests the mediating roles of ascription of responsibility and attitude toward pro-environmental behavior on the examined relationship. Another aim of the study is to explore intention as a mediator in the relationship between attitude toward pro-environmental behavior and behavior. The research is based on the Norm Activation Theory (NAT) and the Theory of Planned Behavior (TPB). A mixed-methods approach was implemented in this study. Quantitatively, a survey was conducted, and 406 responses were collected using convenience sampling …

Hardness Of (Hf,Ti,W,Zr)B2/(Hf,Ti,W,Zr)C-Based Ceramics With Varying Wb Content, Suzana Filipović, William G. Fahrenholtz, Gregory E. Hilmas, Nina Obradović, Stefano Curtarolo

Materials Science and Engineering Faculty Research & Creative Works

Compositionally complex (Hf,Ti,Zr,W)B₂/(Hf,Ti,Zr,W)C-based ceramics were produced with different boride and carbide phase contents by varying the C/B₄C molar ratio used in boro/carbothermal reduction. A monoboride phase based on WB was detected in all compositions. As the C/B₄C ratio was varied, the WB content decreased from 23.7 vol% for a C/B₄C ratio of 6.0–15.3 vol% for a C/B₄C ratio of 10.3. Further increases in the C/B₄C ratio increased the WB content. The monoboride phase contained mainly W and Ti in a solid solution with the nominal composition of (W …

Human Versus Machine: Can Generative Ai Anticipate Insect Biological Control Outcomes?, Kris A.G. Wyckhuys, Komivi S. Akutse, Divina M. Amalin, Salah Eddin Araj, Marie Joy B. Beltran, Ibtissem Ben Fekih, Paul André Calatayud, Lizette Cicero, Marcellin C. Cokola, Yelitza C. Colmenarez, Kenza Dessauvages, Thomas Dubois, Léna Durocher-Granger, José L. Fernández-Triana, Frederic Francis, Khalid Haddi, Rhett D. Harrison, Muhammad Haseeb, Natasha S.A. Iwanicki

All Peer-Reviewed Publications

Generative artificial intelligence (AI) could transform evidence synthesis and revolutionize the global scientific enterprise, yet its agricultural applications are understudied. Here, we systematically assess the performance of three web-grounded AI engines (ChatGPT, ScholarAI and DeepSeek) in synthesizing the global literature on biological control of the fall armyworm Spodoptera frugiperda, and benchmark their outputs against a recent, near-exhaustive human review. Though all engines rapidly screened vast literature corpora, they exhibited shortcomings in factual accuracy, reporting reliability and data consistency. In machine-run syntheses, natural enemy prevalence and performance data often diverged from published records while the level of agreement in enumerating top-performing …

Optimizing Electrode Placement And Information Capacity For Local Field Potentials In Cortex, Jace A Willis, Christopher E Wright, Ruoqian Zhu, Yilan Ruan, Joshua Stallings, Amada M Abrego, Takfarinas Medani, Promit Moitra, Arjun Ramakrishnan, Charles E Schroeder, Anand A Joshi, Nitin Tandon, Richard M Leahy, John C Mosher, John P Seymour

Faculty, Staff and Student Publications

Recent neurosurgery advancements include improved stereotactic targeting and increased density and specificity of electrophysiological evaluation. This study introduces a subject-specific, in silico modeling tool for optimizing electrode placement and maximizing coverage with a variety of devices. The basis for optimization is the Shannon-Hartley information capacity of field potentials derived from dipolar sources. The approach integrates subject-specific MRI data with finite element modeling (FEM) used to simulate the sensitivity of subdural and intracortical devices. Sensitivity maps, or lead fields, from these models enable the comparison of different electrode placements, contact sizes, contact configurations, and substrate properties, which are often overlooked factors. …

Clear And Concise: Technical Writing For Biological Engineers, Abigail S. Engelberth

Purdue University Press Books

Clear and Concise: Technical Writing for Biological Engineers is a practical guide designed to help students and early career engineers communicate their work with clarity and confidence. Drawing on years of teaching experience, Abigail S. Engelberth breaks down the essentials of technical writing into approachable steps, showing readers how to organize ideas, present data effectively, and write reports that meet professional standards.

Rather than overwhelming readers with theory, the book focuses on real-world application. It includes examples, checklists, and strategies for common engineering documents including formal and memo-style lab reports. Special attention is given to visuals, formatting, and the role …

Applied Research In Field Crop Pathology For Indiana, 2023, Darcy E. P. Telenko, Sujoung Shim

Purdue University Press Books

Applied Research in Field Crop Pathology for Indiana, 2023 serves as a summary of the applied field crop pathology research trials conducted in 2023 under the direction of the Purdue Field Crop Pathology program in the Department of Botany and Plant Pathology at Purdue University. In Indiana, there are more than 57,600 farms, 16,000 crop producers, and 900 certified crop advisers, Extension educators, and crop-protection industry representatives who manage more than 11.4 million crop-production acres with a total value of $6.3 billion annually. There are more than twenty diseases affecting corn, soybeans, and wheat that may decrease crop production and …

Teaching Integrated Stem In Middle School, S. Selcen Guzey

Purdue University Press Books

Teaching Integrated STEM in Middle School is a valuable resource for educators, researchers, and policymakers who are committed to furthering integrated STEM education. Through a review of the literature on the topic, the volume offers a clear understanding of the impact of integrated STEM education on instructors’ teaching practices and student outcomes. The book presents a framework and instructional guide that educators can utilize to develop new curricular materials. Two sample units—focused on designing a two-stage water filter and formulating sunscreen—provide step-by-step guidance for lesson implementation and offer strategies for assisting students as they use engineering models to devise design …

Ancient Wisdoms For Modern Crises: Learning From Laozi’S “Daodejing”, Steve Hallett

Purdue University Press Books

We live in a time of abundance and comfort for some, scarcity and hardship for others—a period that seems to have all of us teetering on the brink. Certainly, there is no lack of modern crises, but do we possess the wisdom to overcome them, and where might we seek that wisdom? Ancient Wisdoms for Modern Crises: Learning From Laozi’s “Daodejing[JR1] [ED2] [NN3] ” looks to the Daodejing, a text written during the late Zhou Dynasty (600–400 BCE), for guidance. One of the core treatises of Eastern philosophy, it advocates humility, simplicity, and sustainable living. As both a …

Epistemologies Of Inclusion Across Continents And Cultures, Anne Carr, Athena Alchazidu, Gabriella B. Bonilla, William A. Booth, Antonina Bulyna, Katerina Chudovaf, Pilar Constanzo, Oleh Shlapakov, Jorge L. Schlotteri, Liudmyla Sukhovetska, Patricia Tineo, Olena Yasynetska

Journal of Comparative & International Higher Education

"It is hard to think in two languages when your feet are freezing." Words swim through her head, but she is unable to catch any of them (twelve-year-old Syrian migrant, Warga 2019).

In these ‘liquid’ times of hyper-diversity, students’ lives marked by their identity practices and social relations can tell us how future inclusive global citizenship will be crafted and negotiated. During 2023, students and professors from universities in Ecuador, Argentina, Dominican Republic, United Kingdom, Czech Republic and Ukraine participated in a series of virtual meetings to explore and present the multiple threads that connect the local expression and negotiation …

Nlp-Based Comparative Assessment Of Clauses Quantifying Risk Transfer In Construction Contracts, Hoda M. Elshamy

Theses and Dissertations

Employers in the construction industry mostly deviate from standard contract forms such as FIDIC and NEC, by introducing alterations to the contract conditions that shift a great portion of risks from the client to the contractor. Originally, these risks were distributed more equitably between all contracting parties in the standards forms. The imbalances in the contractual conditions create fertile ground for conflicts, and if not resolved, will escalate to disputes during the project execution phase, leading to significant cost overruns and time delays. The contractors, therefore, attempt to restore the original balance through making amendments to the communicated contract, through …

On Education-Occupation And Skill-Occupation Mismatches Among Generation Z In Egypt, Hamsa Mohamed Ebrahim Yousef Ebrahim

Theses and Dissertations

This thesis examines the impact of education-occupation and skill-occupation mismatches, specifically with regard to Generation Z in Egypt, with a focus on prevalence, socioeconomic factors, and their impact on youth employability and human capital utilization. The research examines education and skill mismatches through a quantitative approach, relying primarily on quantitative analysis of the Egypt Labor Market Panel Survey (ELMPS) 2023 data using multinomial logistic regression for education mismatches and probit regression for skill mismatches. The results indicate that education and skill mismatches are common among employed Gen Z, with a considerable percentage of 38-45%. This is despite the fact that …

Inspect: Intelligent Node-Based System For Ifc Processing And Evaluation, With Conversational Tool Support —Llmassisted Natural Language Ifc Querying, Basel Abdelshaheid

Theses and Dissertations

Industry Foundation Classes (IFC) enables the open exchange of Building Information Models, yet effective validation of real-world IFC deliveries remains challenging. Project models frequently contain incomplete, inconsistent, or incorrectly exported metadata, and explicit IFC relationships are often missing or degraded during conversion from proprietary formats. Many validation questions are inherently spatial, including connectivity, containment, proximity, and clashes, and therefore cannot be answered reliably from properties alone. As a result, federated model validation is often slow, fragmented across tools, and dependent on specialized IFC expertise.

This challenge is increasingly important for coordination, quality assurance, and information management across disciplines and lifecycle …

Scalable And Fault-Tolerant Network Architectures For Real-Time Video Transmission In Industrial Networked Control Systems, Moustafa Awad

Theses and Dissertations

This thesis addresses the challenge of transporting supervisory video alongside time-critical control traffic in industrial Networked Control Systems (NCS) without violating stringent real-time constraints. A simple yet scalable network architecture is developed and evaluated for a plant-level deployment comprising three interconnected workcells with sensors, controllers, actuators, and cameras. The design explicitly accommodates bandwidth-intensive video streams while preserving the responsiveness of watchdog/control traffic. Analytical delay modeling decomposes end-to-end latency into transmission, propagation, processing, and queuing components, and Riverbed-based simulations are used to validate the model under realistic mixed-traffic conditions. A traffic-engineering strategy - phase-shifting supervisory camera transmissions - effectively desynchronizes frame …

The Impact Of Universities’ Social Media Content And Digital Brand Equity On Potential Students’ Perception, Engagement And Trust: The Case Of Egyptian Private Universities, Mahy Shoukry

Theses and Dissertations

Universities are increasingly using social media platforms as tools for marketing, brand building, and student engagement as a result of the digital transformation in higher education. This study investigates how prospective students' perceptions, levels of engagement, and trust are impacted by universities' digital brand equity and social media content. This study attempts to close the knowledge gap on how visual and user-generated information influences the decision-making processes of potential students, given the competitive environment among Egyptian private institutions. Particular focus is placed on how authenticity, video content, and images influence educational institutions' online appearance and reputation. The methodology used a …

Journeys Of Emancipation, Struggle, Or Both? Accounts From Professional Egyptian Migrant Women In Germany, Adam Eddouss

Theses and Dissertations

This thesis explores the migration experiences of a group of professional Egyptian migrant women living in Germany. By employing a qualitative approach, primarily through semi-structured interviews, and guided by migration literature, this research attempts to move away from the oversimplistic approach that migration is an ‘either or’ reality. Mainstream migration scholarship, specifically that focusing on migrant women, tends to focus on depicting migration within an emancipation-struggle binary, presenting migrant women either as victims or as heroines. This work, antithetically, describes how migrant women experiences can be complex, highlighting, both instances of strength and struggle. Grounded in the words of the …

Investigating Tau Pathology In The Retina And Anterior Segment Structures Of The Eye In A 3-Nitropropionic Acid–Induced Tauopathy Mouse Model, Mohamed Sayed Ahmed Abdel-Kader Qasem

Theses and Dissertations

Background and Objectives: Alzheimer's disease, the most prevalent neurodegenerative disorder in older adults, is characterized by accumulation of hyperphosphorylated tau and amyloid-beta (Aβ) plaques in the central nervous system. Given the retina's shared embryological origin with the brain, its direct neural connectivity via the optic nerve, and similarities in vasculature and age-related degeneration patterns, retinal pathology may serve as an early, non-invasive biomarker for Alzheimer's disease. This study employed 3-nitropropionic acid (3NP) as a pathway-specific tauopathy model driven by mitochondrial dysfunction. The study particularly aimed to investigate whether retinal and corneal tau pathology reflects underlying tau-related neurodegeneration triggered by …

Metagenomic Profiling Of Gut Microbiome Signatures Across Liver Disease Stages And Hcv-Related Hepatocellular Carcinoma In Egyptian Patients, Marwa A. Zahra

Theses and Dissertations

Dysbiosis in the gut microbiome, particularly concerning the synchronous crosstalk between the gut and the liver, has been associated with various diseases. This study profiles the gut microbiome in liver diseases among Egyptian patients, with a focus on the hepatitis C virus (HCV) and hepatocellular carcinoma (HCC), both of which are highly prevalent in Egypt. Utilizing shotgun metagenomic sequencing, we analyzed microbial gene catalogs and taxonomic profiles from 46 Egyptian patients categorized into five groups: healthy individuals, liver disease patients of different etiologies, post-HCV, treated HCV, and HCV-HCC patients. Healthy and treated HCV patients exhibited distinct microbial profiles characterized by …

Development Of A Novel Innovative Umbrella Falsework System For Concrete Slabs, Abdelazem Hashim

Theses and Dissertations

Formwork is one of the major elements that contribute to the cost and duration of concrete building projects. This is why optimizing such an element can lead to huge savings to all parties involved in the construction projects. With contractors facing huge challenges in such a competitive industry and employers seeking the least price and least duration for their projects, contractors are constantly under the obligations of finding the best alternatives to deliver their projects in terms of both time and money. Therefore, the main aim of this research project is to develop a falsework system, where the falsework system …

Comparative Evaluation Of Conventional And Sustainable Concrete Protective Coatings: Performance, Economic, And Environmental, Andro Ebrahim

Theses and Dissertations

Concrete structures are highly susceptible to deterioration from environmental, chemical, and mechanical factors, making protective coatings essential for ensuring durability and reducing maintenance demands. This study aims to compare and evaluate conventional and innovative coating systems for concrete protection across three dimensions—technical performance, environmental sustainability, and life cycle cost efficiency—and to assess whether coatings often regarded or marketed as sustainable genuinely achieve sustainability across these three pillars. Four representative coatings were selected for assessment: epoxy solvent-based, epoxy solvent-free, acrylic water-based, and cementitious. Technical performance was examined through laboratory testing, expert interviews, and multiple real project cases, providing a comprehensive understanding …

Sustainable Construction Materials In The Middle East: Model Development For Materials Selection, Taha Ahmed Omar Madu

Theses and Dissertations

The construction industry, a major driver of economic development in the Middle East, is simultaneously a leading contributor to carbon emissions, resource depletion, and environmental degradation. Amid rapid urbanization in countries such as Egypt, Saudi Arabia, and the United Arab Emirates, the adoption of sustainable construction materials has emerged as a critical strategy for mitigating environmental and societal impacts while advancing regional development objectives. This thesis is organized along two interrelated directions: first, it delivers a comprehensive assessment of the current adoption, challenges, and opportunities associated with the use of sustainable construction materials across the three target countries; second, it …

Flexible Fault-Tolerant Multi-Die Fpga-Based Architectures For Varying Space Environments, Yosof Ali Seif El Din Ali Maklad

Theses and Dissertations

It is well-known fact that spacecraft’s electronic components operate in an extreme harsh and varying space environments, beside changing orbit or passing through Van Allan Belts during orbital course results of radiation levels change. This thesis focuses on SRAM-based FPGA systems on-board of such spacecrafts, that are commonly utilized in space applications’ critical applications due to their capabilities and flexibility to reconfigure, since these systems are vulnerable to frequent negative impacts of ionizing radiation, thus inducing soft and hard errors leading to disastrous failures that could jeopardize the entire spacecraft. The soft errors’ effects are frequent yet can be mitigated, …

Post Tension Losses: A Comparative Study Of Different Codes Of Practice, Hana Moataz Tolba

Theses and Dissertations

Pre-stressed post-tensioned concrete has become a cornerstone of contemporary structural design due to its ability to enhance load-bearing capacity, minimize deflections, and extend span lengths efficiently. Accurate estimation of pre-stress losses is essential for ensuring structural reliability and serviceability over the lifespan of such systems. This study presents a comprehensive evaluation of initial and long-term pre-stress losses in post-tensioned concrete elements, applying and comparing provisions from four major international design codes: The Egyptian Code for Design and Construction of Concrete Structures (ECP 203-2007), the American Concrete Institute's ACI 423.10R-16, Euro code 2, and the Canadian CSA A23.3 standards as detailed …

The Effectiveness Of Public-Private Partnerships In Addressing Residential Urban Development Challenges In Greater Cairo, Sara Nagy Abdelmessih

Theses and Dissertations

This research explores the effectiveness of Public-Private Partnerships (PPPs) in tackling the residential urban development challenges facing Cairo today. In the past two decades, PPPs have emerged as a dominant mode of housing production, positioned as collaborative ventures between state agencies and private developers. They have become integral to the expansion of Greater Cairo, producing vast new urban extensions under the promise of mobilizing private capital, technical expertise, and delivery capacity. Yet, questions remain about whether these arrangements genuinely address Egypt’s most urgent housing needs, or whether they reproduce market-driven logics that leave large segments of the population excluded.

The …

Global Public Health Feasibility: Digital Dentistry In Geriatric Population, Merna Amr Saleh

Theses and Dissertations

Oral health is a critical yet often overlooked determinant of well-being among older adults in Egypt, where mobility limitations, geographic barriers, and low awareness of preventive practices exacerbate dental disparities. DentalPal, a teledentistry-based mobile application, was developed to provide older adults with remote dental consultations, oral hygiene advice, and triage guidance. The platform enables users to submit oral photographs or radiographs for assessment, seek second opinions, and initiate follow-up chats directly with the healthcare provider. This flexible design allows users to access dental consultations on demand while ensuring continuity of care The question that guided this study was how older …

Facebook Interaction As A Potential Marker Of Cognitive Decline: Pilot Study, Esraa M. Qansuwa

Theses and Dissertations

One of the critical challenges in brain disorder research is the early identification of individuals with mild cognitive impairment (MCI) who may later develop Alzheimer’s disease (AD) or other dementias. MCI in older adults is frequently associated with diminished social engagement and observable behavioral changes. With the rapid expansion of social media platforms and advances in Machine Learning (ML), digital traces from online activity present a novel and scalable avenue for mental health screening. In particular, predictive ML approaches have demonstrated strong potential in building reliable classifiers for early detection of neurocognitive decline. This study introduces an innovative framework that …

Perceptions Of Healthcare Access Barriers Among Eritrean, Sudanese, And Somali Refugees And Asylum Seekers In Cairo., Ayan Musa Mohamed

Theses and Dissertations

As the world witnesses an increase in different displacements of individuals for various reasons, ranging from wars, civil conflicts, human rights violations, and natural disasters, refugees and asylum seekers, who are among those forcibly displaced, continue to face challenges in access to health care services in host countries. The topic of barriers to health care has been widely researched, with a large body of literature on refugees' interactions with health care systems. However, there is limited literature on the perceptions of Eritrean, Sudanese, and Somali refugees and asylum seekers' experience with healthcare access in host countries. Therefore, this thesis aims …

Assessing Knowledge, Attitudes, And Practices (Kap) Towards The One Health Approach In Governmental Officers In Egypt, Nour Elsersawy

Theses and Dissertations

Background: the one health (OH) approach emphasizes the interconnectedness among human, animal, and environmental health and requires multisectoral collaboration to address complex health challenges. Egypt faces significant threats at the human-animal-environment interface, including endemic and emerging zoonotic diseases, antimicrobial resistance (AMR), food safety challenges, and vector-borne diseases. Despite established coordination mechanisms and the launch of the One Health National strategic framework (2023-2027) of Egypt, the extent to which oh principles are understood, embraced, and practiced by governmental officers responsible for implementation remains incompletely understood. Objectives: this study assessed and evaluated the knowledge, attitudes, and practices (KAP) regarding the one health …

Proposed Modifications To The Egyptian Concrete Code Based On A Comprehensive Sustainability Assessment Of Portland Cement Alternatives For Climate Change Mitigation, Yasmin Elhakim

Theses and Dissertations

Climate change is a major challenge facing planet earth today. This phenomenon is foreseen to continue to represent a major concern for decades to come. The construction industry is one of the most polluting sectors worldwide and is considered one of the top greenhouse gas emitters. Egypt, in particular, is one of the most vulnerable countries to the adverse effects of climate change. The construction sector plays a major role in Egypt’s economy, contributing significantly to the national GDP, yet it also represents one of the country’s largest greenhouse gas emitters. However, the Egyptian Concrete Code does not enforce the …

Uncovering Potential Therapeutic Targets For Spinal Cord Injury; Insights From Single-Cell And Cross-Species Transcriptomics, Sara Samy Abouzekry

Theses and Dissertations

Central nervous system (CNS) injury remains a devastating healthcare problem. Despite years of research, it remains almost impossible to achieve meaningful functional repair following traumatic brain injury (TBI) and spinal cord injury (SCI). Spinal cord injury (SCI), a highly devastating subset of CNS trauma, is considered a challenge due to the extremely limited regenerative capacity of the nervous system in adult mammals. In contrast, certain species display remarkable repair abilities followed by moderate regenerative ability in neonatal mammals, indicating that regeneration is shaped by the evolutionary context as well as the developmental age.

To uncover the core molecular mediators of …