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Current Neurologic Treatment And Emerging Therapies In Cdkl5 Deficiency Disorder, Heather E Olson, Judith L Weisenberg, Et Al. Sep 2021

Current Neurologic Treatment And Emerging Therapies In Cdkl5 Deficiency Disorder, Heather E Olson, Judith L Weisenberg, Et Al.

2020-Current year OA Pubs

BACKGROUND: CDKL5 deficiency disorder (CDD) is associated with refractory infantile onset epilepsy, global developmental delay, and variable features that include sleep, behavioral disturbances, and movement disorders. Current treatment is primarily symptom-based and informed by experience in caring for this population.

METHODS: We describe medication and non-medication approaches to treatment of epilepsy and additional key neurologic symptoms (sleep disturbances, behavioral issues, movement disorders, and swallowing dysfunction) in a cohort of 177 individuals meeting criteria for CDD, 154 evaluated at 4 CDKL5 Centers of Excellence in the USA and 40 identified through the NIH Natural History Study of Rett and Related Disorders. …


Unh Research Finds Witnessing Abuse Of Sibling Can Lead To Mental Health Issues, Robbin Ray Sep 2021

Unh Research Finds Witnessing Abuse Of Sibling Can Lead To Mental Health Issues, Robbin Ray

Media Relations

No abstract provided.


Comparing Institutional Strategies For Engineering Ethics Education In Regional, National And European Contexts, Gunter Bombaerts, Luis Adriano, Shannon Chance, Václav Čuba, Mihály Héder, Sarah Junaid, Aleksandra Kazakova, Helena Kovacs, Thomas Lennerfors, Diana Martin, Amirouche Moktefi, Alfredo Soeiro, Andrei Simionescu-Panait, Mircea Toboșaru, Roland Tormey, Horațiu Vermeșan Sep 2021

Comparing Institutional Strategies For Engineering Ethics Education In Regional, National And European Contexts, Gunter Bombaerts, Luis Adriano, Shannon Chance, Václav Čuba, Mihály Héder, Sarah Junaid, Aleksandra Kazakova, Helena Kovacs, Thomas Lennerfors, Diana Martin, Amirouche Moktefi, Alfredo Soeiro, Andrei Simionescu-Panait, Mircea Toboșaru, Roland Tormey, Horațiu Vermeșan

Research Outputs: 2025-Present

This paper describes, at raw-data level, the results of a workshop at SEFI 2021 on “comparing institutional strategies for engineering ethics education in regional, national and European contexts”. It uses the curriculum typology of Goodlad. The results indicate the diversity of answers at the European scale for the ideal, formal, perceived and operational curriculum. Although there were some first contextual differences noticeable, the set of answers was too small to give an in-depth analysis, but it opens up a promising area for future research.


Bird Courtship Rituals Topic For Virtual Science Cafe, Edwin B. Smith Sep 2021

Bird Courtship Rituals Topic For Virtual Science Cafe, Edwin B. Smith

University of Mississippi News

Neuroscience professor to discuss manakin study during Sept. 21 Zoom event


The Concise Guide To Pharmacology 2021/22: Enzymes, Stephen Ph Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Christopher Southan, James A. Davies, Detlan Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angela A. Izzo, Doris Koesling, Rennolds Ostrom, Nigel J. Pyne, Susan Pyne, Michael Russwurm, Roland Seifert, Johannes-Peter Stasch, Mario Van Der Stelt, Albert Van Der Vliet, Val Watts, Szu Shen Wong Sep 2021

The Concise Guide To Pharmacology 2021/22: Enzymes, Stephen Ph Alexander, Doriano Fabbro, Eamonn Kelly, Alistair Mathie, John A. Peters, Emma L. Veale, Jane F. Armstrong, Elena Faccenda, Simon D. Harding, Adam J. Pawson, Christopher Southan, James A. Davies, Detlan Boison, Kathryn Elisa Burns, Carmen Dessauer, Jürg Gertsch, Nuala Ann Helsby, Angela A. Izzo, Doris Koesling, Rennolds Ostrom, Nigel J. Pyne, Susan Pyne, Michael Russwurm, Roland Seifert, Johannes-Peter Stasch, Mario Van Der Stelt, Albert Van Der Vliet, Val Watts, Szu Shen Wong

Pharmacy Faculty Articles and Research

The Concise Guide to PHARMACOLOGY 2021/22 is the fifth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of nearly 1900 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide constitutes over 500 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record …


Design Of A Custom Digital Light Projection Printer For In-Situ Production Of Composites With Improved Thermomechanical Properties, Margaret Anne Gillan Sep 2021

Design Of A Custom Digital Light Projection Printer For In-Situ Production Of Composites With Improved Thermomechanical Properties, Margaret Anne Gillan

Theses and Dissertations

This work seeks to improve upon the existing state-of-the-art for vat photopolymerization additive manufacturing; namely, producing in-situ composites that combine the precision and high-performance materials of the vat photopolymerization with the strength of fiber-reinforced polymer composites. A custom-designed digital light projection printer was designed and built for printing composites, which includes an automated fiber tape system to place woven E-glass fiber mats in-situ. To validate the performance improvement of composites versus the neat matrix, composites were fabricated on the custom printer with hand-placed fiber mats. A high-performance, dual-cure resin was used for these studies. The effect of layer height on …


Speech By Dr. Ishrat Hussain On Infosec Conference, Ishrat Hussain Dr. Sep 2021

Speech By Dr. Ishrat Hussain On Infosec Conference, Ishrat Hussain Dr.

Faculty Research - Talks, Speeches, & Discourse

Ladies and gentlemen, I feel so happy to be part of 13th annual InfoSec conference. Thank you, TOTAL Communications, and IoBM and HBL for giving me this opportunity to speak on such a critically important subject and I am glad to see such a variety of very learned experts present on this floor today. So proud to see Pakistani talent like Kaleed rising and contributing immensely in other parts of the world. Also nice to see HBL co hosting today's event and I am told that HBL has been leading this premier annual conference for the last four years.


Blood Biomarkers For Mild Traumatic Brain Injury: A Selective Review Of Unresolved Issues, Daniel B. Hier, Tayo Obafemi-Ajayi, Matthew S. Thimgan, Gayla R. Olbricht, Sima Azizi, Blaine Allen, Bassam A. Hadi, Donald C. Wunsch Sep 2021

Blood Biomarkers For Mild Traumatic Brain Injury: A Selective Review Of Unresolved Issues, Daniel B. Hier, Tayo Obafemi-Ajayi, Matthew S. Thimgan, Gayla R. Olbricht, Sima Azizi, Blaine Allen, Bassam A. Hadi, Donald C. Wunsch

Biological Sciences Faculty Research & Creative Works

Background: The use of blood biomarkers after mild traumatic brain injury (mTBI) has been widely studied. We have identified eight unresolved issues related to the use of five commonly investigated blood biomarkers: neurofilament light chain, ubiquitin carboxy-terminal hydrolase-L1, tau, S100B, and glial acidic fibrillary protein. We conducted a focused literature review of unresolved issues in three areas: mode of entry into and exit from the blood, kinetics of blood biomarkers in the blood, and predictive capacity of the blood biomarkers after mTBI.

Findings: Although a disruption of the blood brain barrier has been demonstrated in mild and severe traumatic brain …


The Cowl - V. 86 N. 2 - Sep 16, 2021 Sep 2021

The Cowl - V. 86 N. 2 - Sep 16, 2021

The Cowl

The Cowl - student newspaper of Providence College. Vol. 86 No. 2 - September 16, 2021. 20 pages.


Research Snapshot: Protecting Great Bay, Tim Briggs Sep 2021

Research Snapshot: Protecting Great Bay, Tim Briggs

UNH Today Archive

No abstract provided.


September 2021 Academic Affairs Minutes, University Of Nebraska At Kearney Academic Affairs Committee Sep 2021

September 2021 Academic Affairs Minutes, University Of Nebraska At Kearney Academic Affairs Committee

Academic Affairs Committee Minutes

No abstract provided.


The Structure Of Finite Commutative Idempotent Involutive Residuated Lattices, Peter Jipsen, Olim Tuyt, Diego Valota Sep 2021

The Structure Of Finite Commutative Idempotent Involutive Residuated Lattices, Peter Jipsen, Olim Tuyt, Diego Valota

Mathematics, Physics, and Computer Science Faculty Articles and Research

We characterize commutative idempotent involutive residuated lattices as disjoint unions of Boolean algebras arranged over a distributive lattice. We use this description to introduce a new construction, called gluing, that allows us to build new members of this variety from other ones. In particular, all finite members can be constructed in this way from Boolean algebras. Finally, we apply our construction to prove that the fusion reduct of any finite member is a distributive semilattice, and to show that this variety is not locally finite.


Messages From The Provost, Georgia Southern University Sep 2021

Messages From The Provost, Georgia Southern University

Messages from the Provost

September 16, 2021: Public Impact Research


The Missouri Miner, September 16, 2021 Sep 2021

The Missouri Miner, September 16, 2021

The Missouri Miner Newspaper

No abstract provided.


September 16, 2021, James Madison University Sep 2021

September 16, 2021, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.


September 16, 2021, The Daily Mississippian Sep 2021

September 16, 2021, The Daily Mississippian

Daily Mississippian (all digitized issues)

No abstract provided.


Cognition-Enhanced Machine Learning For Better Predictions With Limited Data, Florian Sense, Ryan Wood, Michael G. Collins, Joshua Fiechter, Aihua W. Wood, Michael Krusmark, Tiffany Jastrzembski, Christopher W. Myers Sep 2021

Cognition-Enhanced Machine Learning For Better Predictions With Limited Data, Florian Sense, Ryan Wood, Michael G. Collins, Joshua Fiechter, Aihua W. Wood, Michael Krusmark, Tiffany Jastrzembski, Christopher W. Myers

Faculty Publications

The fields of machine learning (ML) and cognitive science have developed complementary approaches to computationally modeling human behavior. ML's primary concern is maximizing prediction accuracy; cognitive science's primary concern is explaining the underlying mechanisms. Cross-talk between these disciplines is limited, likely because the tasks and goals usually differ. The domain of e-learning and knowledge acquisition constitutes a fruitful intersection for the two fields’ methodologies to be integrated because accurately tracking learning and forgetting over time and predicting future performance based on learning histories are central to developing effective, personalized learning tools. Here, we show how a state-of-the-art ML model can …


Uav-Assisted Data Dissemination Based On Network Coding In Vehicular Networks, Shidong Huang, Chuanhe Huang, Yabo Yin, Dongfang Wu, M. Wasim Abbas Ashraf, Bin Fu Sep 2021

Uav-Assisted Data Dissemination Based On Network Coding In Vehicular Networks, Shidong Huang, Chuanhe Huang, Yabo Yin, Dongfang Wu, M. Wasim Abbas Ashraf, Bin Fu

Computer Science Faculty Publications

Efficient and emergency data dissemination service in vehicular networks (VN) is very important in some situations, such as earthquakes, maritime rescue, and serious traffic accidents. Data loss frequently occurs in the data transition due to the unreliability of the wireless channel and there are no enough available UAVs providing data dissemination service for the large disaster areas. UAV with an adjustable active antenna can be used in light of the situation. However, data dissemination assisted by UAV with the adjustable active antenna needs corresponding effective data dissemination framework. A UAV-assisted data dissemination method based on network coding is proposed. First, …


Fine-Scale Spatial And Diel Dynamics Of Zooplanktivorous Fish On Temperate Rocky And Artificial Reefs, Mm Holland, A Becker, Ja Smith, Jd Everett, Im Suthers Sep 2021

Fine-Scale Spatial And Diel Dynamics Of Zooplanktivorous Fish On Temperate Rocky And Artificial Reefs, Mm Holland, A Becker, Ja Smith, Jd Everett, Im Suthers

School of Biological and Marine Sciences

Plankton is an important component of the food web in coastal reef ecosystems. Ocean currents subsidise local production by supplying plankton to resident and reef-associated planktivorous fishes. Measuring the fine-scale distribution of these schooling fishes provides insight into their habitat use and how they balance risk and reward while foraging for plankton. Maintaining their proximity to benthic structure can provide refuge from predation but may also limit foraging opportunities. We used a portable multibeam echosounder to survey schooling fish at 5 natural and 3 artificial reefs, during day and night and under different current conditions. We isolated midwater acoustic targets …


Identifying Juvenile And Sub-Adult Movements To Inform Recovery Strategies For A High Value Fishery—European Bass (Dicentrarchus Labrax), Thomas Stamp, David Clarke, Shaun Plenty, Tim Robbins, James E. Stewart, Elizabeth West, Emma Sheehan Sep 2021

Identifying Juvenile And Sub-Adult Movements To Inform Recovery Strategies For A High Value Fishery—European Bass (Dicentrarchus Labrax), Thomas Stamp, David Clarke, Shaun Plenty, Tim Robbins, James E. Stewart, Elizabeth West, Emma Sheehan

School of Biological and Marine Sciences

Abstract The European bass (Dicentrarchus labrax) support high value commercial and recreational fisheries, however the Spawning Stock Biomass (SSB) of the northern Atlantic stock (ICES divisions 4.b–c, 7.a, and 7.d–h) has rapidly declined to an unsustainable level. The decline in SSB has been attributed to high fishing pressure combined with poor recruitment. By tracking juvenile fish their spatial ecology can be identified, and appropriate fisheries management policies designed to boost recruitment can be implemented. Using acoustic telemetry 146 sub-adult European bass (25.2–60 cm fork length) were tracked for up to 370 d across three sites in the southwest of the …


Taxing The Ivory Tower: Evaluating The Excise Tax On University Endowments, Jennifer Bird-Pollan Sep 2021

Taxing The Ivory Tower: Evaluating The Excise Tax On University Endowments, Jennifer Bird-Pollan

Pepperdine Law Review

The Tax Cuts and Jobs Act of 2017 introduced the first-ever excise tax imposed on the investment income of university endowments. While it is a relatively small tax, this new law is a first step towards the exploration of taxing non-profit entities on the vast sums of wealth they hold in their endowments. In this essay I take the new tax as a starting place for investigating the justification for tax exemption for universities and thinking through the consequences of changing our approach, both in the form of the new excise tax and possible alternatives. There remain reasons to be …


The Bird Islands Off Englishtown, Nova Scotia, Stephanie Kraft Sep 2021

The Bird Islands Off Englishtown, Nova Scotia, Stephanie Kraft

Appalachia

No abstract provided.


Books And Media Sep 2021

Books And Media

Appalachia

AMC’s Best Day Hikes in the Berkshires by Rene Laubach and John S. Burk. White Mountain Winter Recreation Map and Guide. Best Backcountry Skiing in the Northeast by David Goodman. An Ice Climber’s Guide to Southern New England and Eastern New York by Todd Swain. Black Woman in Green by Gloria D. Brown and Donna L. Sinclair. Black Faces, White Spaces by Carolyn Finney. In Search of Amos Clough by Robert W. Averill. Waymaking: An Anthology of Women’s Adventure Writing, Poetry and Art (edited by Helen Mort et al). Paul Preuss: Lord of the Abyss by David Smart. …


The Story Of Scar Ridge: A Trailless Tangle In The Southern White Mountains, Steven D. Smith Sep 2021

The Story Of Scar Ridge: A Trailless Tangle In The Southern White Mountains, Steven D. Smith

Appalachia

Steven D. Smith, an accomplished bushwhacker and editor of the Appalachian Mountain Club’s White Mountain Guide, describes the trailless tangle in the southern White Mountains of New Hampshire.


Summer/Fall 2021: Off Trail Sep 2021

Summer/Fall 2021: Off Trail

Appalachia

Summer/Fall 2021 - Volume LXXII, Number 2 - Issue #252. Off Trail: Trailless tangles, bushwhacking, river crossings, helpful strangers, and more.


The Factors Impacting The Incorporation Of The Sustainable Development Goals Into Raw Materials Engineering Curricula, Dimitris Damigos, George Valakas, Anna Gaki, Katerina Adam Sep 2021

The Factors Impacting The Incorporation Of The Sustainable Development Goals Into Raw Materials Engineering Curricula, Dimitris Damigos, George Valakas, Anna Gaki, Katerina Adam

Journal of Sustainable Mining

It is widely recognised and acknowledged that the mining industry, if properly operating and managed, has the potential to positively contribute to “The 2030 Agenda for Sustainable Development”. In this direction, the Raw Materials (RM) engineering education possesses a crucial role, given the need to instil in tomorrow’s mining engineers the sustainability principles. This paper explores the educational needs of the Greek RM sector and the factors constituting the RM whole value chain SDGs-education-innovation eco-system. The research follows a two-stage focus group approach. First, the perceptions, opinions and beliefs of invited stakeholders were explored in the context of semi-structured interviews. …


Hidden In Plain Sight: Why Sustainment Is So Critical To The Circular Supply Chains For Technical Products, Dave Peterson Sep 2021

Hidden In Plain Sight: Why Sustainment Is So Critical To The Circular Supply Chains For Technical Products, Dave Peterson

Operations Management Presentations

  • Technical products are typically complex, long-lived and high-cost equipment—such as: aircraft, vehicles, ships, capital equipment/machinery and utilities infrastructure. While many technical products are manufactured via traditional linear supply chains, their useful lives often rely upon sustainment systems incorporating significant aspects of circular supply chains. This webinar takes a closer look at technical products and the critical role of systems sustainment to achieve and fulfill circular supply chains. The key takeaways from this webinar are:
    • The Earth is running out of resources which will have a direct impact upon maintaining/improving our quality of life.
    • The circular economy philosophy has definite relevance …


09-15-2021 Swosu Family Day Is September 25, Southwestern Oklahoma State University Sep 2021

09-15-2021 Swosu Family Day Is September 25, Southwestern Oklahoma State University

THE BARK ARCHIVE 2021

No abstract provided.


Commonwealth Times 2021-09-15 Sep 2021

Commonwealth Times 2021-09-15

Commonwealth Times, 1969-

No abstract provided.


Alternatives To Open Burning And Open Detonation: The Disparity Between Hma And Commercial Best Practices, Linsey Cottrell, Kendra Dupuy Sep 2021

Alternatives To Open Burning And Open Detonation: The Disparity Between Hma And Commercial Best Practices, Linsey Cottrell, Kendra Dupuy

The Journal of Conventional Weapons Destruction

cisrExchange · 25.1-Cottrell

Munition and explosive residues have the potential to cause long-term harm when released into the environment. Common explosives, such as TNT and RDX are toxic, with both classed as possible carcinogens.1,2 The environmental fate of explosives is complex and varied. TNT absorbs onto soil, slowly leaches, and degrades to form degradation products such as DNT, which has a higher toxicity than TNT itself.3 RDX leaches from soil more readily, degrades slowly, and can persist in the environment. The residual soil and water contamination at military ranges caused by the firing, detonation, and disposal of munitions …