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Articles 195031 - 195060 of 1114496

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Cochlear Inflammaging In Relation To Ion Channels And Mitochondrial Functions, Parveen Bazard, Jennifer Pineros, Robert D. Frisina, Mark A. Bauer, Alejandro A. Acosta, Lauren R. Paganella, Dominika Borakiewicz, Mark Thivierge, Freyda L. Mannering, Xiaoxia Zhu, Bo Ding Oct 2021

Cochlear Inflammaging In Relation To Ion Channels And Mitochondrial Functions, Parveen Bazard, Jennifer Pineros, Robert D. Frisina, Mark A. Bauer, Alejandro A. Acosta, Lauren R. Paganella, Dominika Borakiewicz, Mark Thivierge, Freyda L. Mannering, Xiaoxia Zhu, Bo Ding

Chemical and Biochemical Engineering Faculty Research & Creative Works

The slow accumulation of inflammatory biomarker levels in the body—also known as inflammation—has been linked to a myriad of age-related diseases. Some of these include neurodegenerative conditions such as Parkinson's disease, obesity, type II diabetes, cardiovascular disease, and many others. Though a direct correlation has not been established, research connecting age-related hearing loss (ARHL)—the number one communication disorder and one of the most prevalent neurodegenerative diseases of our aged population—and inflammation has gained interest. Research, thus far, has found that inflammatory markers, such as IL-6 and white blood cells, are associated with ARHL in humans and animals. Moreover, studies investigating …

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Sustainable Maritime Crude Oil Transportation: A Split Pickup And Split Delivery Problem With Time Windows, Hiba Yahyaoui, Nadia Dahmani, Saoussen Krichen Oct 2021

Sustainable Maritime Crude Oil Transportation: A Split Pickup And Split Delivery Problem With Time Windows, Hiba Yahyaoui, Nadia Dahmani, Saoussen Krichen

All Works

This paper studies a novel sustainable vessel routing problem modeling considering the multi-compartment, split pickup and split delivery, and time windows concepts. In the presented problem, oil tankers transport crude oil from supply ports to demand ports around the globe. The objective is to find ship routes, as well as port arrival and departure times, in a way that minimizes transportation costs. As a second objective, we considered the sustainability aspect by minimizing the vessel energy efficiency operational indicator. Multiple products are transported by a heterogeneous fleet of tankers. Small realistic test instances are solved with the exact method.

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Analysis Of Newtonian Heating And Higher-Order Chemical Reaction On A Maxwell Nanofluid In A Rotating Frame With Gyrotactic Microorganisms And Variable Heat Source/Sink, Yu-Ming Chu, Muhammad Ramzan, Naila Shaheen, Jae Dong Chung, Seifedine Kadry, Fares Howari, M.Y. Malik, Hassan Ali S. Ghazwani Oct 2021

Analysis Of Newtonian Heating And Higher-Order Chemical Reaction On A Maxwell Nanofluid In A Rotating Frame With Gyrotactic Microorganisms And Variable Heat Source/Sink, Yu-Ming Chu, Muhammad Ramzan, Naila Shaheen, Jae Dong Chung, Seifedine Kadry, Fares Howari, M.Y. Malik, Hassan Ali S. Ghazwani

All Works

The goal of this study is to investigate the rotating Maxwell nanoliquid flow incorporating gyrotactic microbes with Newtonian heating and irregular heat source sink. The motion of the flow is induced due to linearly unidirectional elongated surface. The uniqueness of the flow is enhanced by the inclusion of additional phenomenon of higher order chemical reaction incorporated with Darcy Forchheimer flow, Fourier and Fick law. Numerical solution of the formulated problem is developed via bvp4c function in MATLAB. The influence of the embroiled parameters on the flow distribution is demonstrated through various graphs and tables. It is noticed that fluid velocity …

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On The Right Path: Youth Development Amidst Colombia’S Sociocultural Transition, Holly Follmer-Reece, Paulina Velez-Gomez, Nadia Semenova Moratto-Vásquez, Sara Dodd Oct 2021

On The Right Path: Youth Development Amidst Colombia’S Sociocultural Transition, Holly Follmer-Reece, Paulina Velez-Gomez, Nadia Semenova Moratto-Vásquez, Sara Dodd

Journal of Youth Development

Colombia is amidst a sociocultural transition due to recent political movements towards ending the long-standing internal armed conflict. Development and implementation of youth programs that are responsive to the current societal context can contribute to this transition by investing in younger generations. This study features findings from the exploration phase of a community-based participatory research study to adapt a youth program from the United States for implementation in Colombia. Through focus group interviews, participants representing 4 different microsystems surrounding youth shared perceptions of youth who will be successful in this transitional context. Perceptions coalesced to reveal a process of positive …

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Positive Youth Development In Senegal: A Case Study Of 4-H Senegal, Thomas Archibald, Bineta Guisse, Amadou Ndiaye, Fatimata Kane Oct 2021

Positive Youth Development In Senegal: A Case Study Of 4-H Senegal, Thomas Archibald, Bineta Guisse, Amadou Ndiaye, Fatimata Kane

Journal of Youth Development

African youth face great challenges and great opportunities. Positive youth development (PYD) programs have the potential to support youth in Africa to reach their full potential. Yet PYD approaches must be tailored if they are to be contextually and culturally responsive and relevant. The purpose of this paper is to provide an evidence-informed description of one such program, the 4-H Senegal PYD program. We first provide a conceptual background for the program, informed especially by the literature on global and cross-cultural PYD. We then share empirical results of a qualitative case study focused on the establishment, scale-up, and institutionalization of …

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Dynamic Material Properties Copper Mountain Sandstone Under Uniaxial And Oblique Impact, Nathaniel Steven Helminiak Oct 2021

Dynamic Material Properties Copper Mountain Sandstone Under Uniaxial And Oblique Impact, Nathaniel Steven Helminiak

Dissertations (1934 -)

A generalized P-Lambda equation of state and strength model (dependent on hydrostatic and deviatoric stress terms) for porous alpha phase crystalline quartz under compression load was generated utilizing Copper Mountain sandstone (from Mosinee WI) and augmented with existing petrographic data. Tests with Copper Mountain sandstone samples began with an examination of elastic properties before conventional low strain rate testing was conducted. Sample thickness varying from ~0.5 mm to ~3.0 mm, were tested in high strain rate plane strain and pressure-shear configurations at impact velocities from 3 m/s to 720 m/s. Each plane strain test contained multiple sandstone samples so that …

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Thermal Deformation In High Pressure Die Casting Shot Sleeves, Ross Crowley Oct 2021

Thermal Deformation In High Pressure Die Casting Shot Sleeves, Ross Crowley

Dissertations (1934 -)

Replacement of shot sleeves represents a significant cost in cold chamber high pressure die casting (HPDC) processes. It is well known that the service life of a shot sleeve is closely related to its thermomechanical deformation behavior, so an improved understanding of this behavior is needed to guide the design of shot sleeves for increased service life. Prior research efforts have analyzed shot sleeve deformation but were based on 2D representations and did not consider transient effects from the molten metal’s flow behavior. This objective of this study was to analyze thermo-mechanical deformation during the injection sequence by using a …

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The Anchor: Fall 2021, Issue Iii, Hope College Oct 2021

The Anchor: Fall 2021, Issue Iii, Hope College

The Anchor: 2021

The Anchor began in 1887 and was first issued weekly in 1914. Covering national and campus news alike, Hope College’s student-run newspaper has grown over the years to encompass over two-dozen editors, reporters, and staff. For much of The Anchor's history, the latest issue was distributed across campus each Wednesday throughout the academic school year (with few exceptions). In recent years The Anchor moved to monthly print issues and a more frequently updated website. The Anchor is now published in print twice per academic semester. Occasionally, the volume and/or issue numbering is irregular.

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Exploring Sea Surface Temperature’S Effect On Global Ocean Productivity In Our Changing Climate, Jessica Gray Oct 2021

Exploring Sea Surface Temperature’S Effect On Global Ocean Productivity In Our Changing Climate, Jessica Gray

Inquiry Journal Fall 2021

Jessica investigates the multitude of variables that affect productivity of our global ocean and how that productivity relates to climate change.

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2021 Fall Newsletter, Morehead State University. Nursing Department. Oct 2021

2021 Fall Newsletter, Morehead State University. Nursing Department.

Nursing Department Publications Archive

2021 Fall Newsletter of the Department of Nursing at Morehead State University.

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2021 (Fall) Ensi Informer Magazine, Morehead State University. Engineering Sciences Department Oct 2021

2021 (Fall) Ensi Informer Magazine, Morehead State University. Engineering Sciences Department

ENSI Informer Magazine Archive

The ENSI Informer Magazine published in the fall of 2019.

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Mid-Movement Error Corrections After Visual And Haptic Perturbations Reflect Latency And Performance Differences, Pablo Gonzalez Polanco Oct 2021

Mid-Movement Error Corrections After Visual And Haptic Perturbations Reflect Latency And Performance Differences, Pablo Gonzalez Polanco

Master's Theses (2009 -)

We examined a key attribute of sensory motor skill: the capability to adjust ongoing actions to correct performance errors that arise during the execution of a task. Fifteen subjects grasped the handle of a horizontal 2D planar robot that enacted a small viscous resistance to the arm movement. The subjects initiated interception movements using a prompted Go cue to quickly catch a pseudo-randomly moving target. On some trials, the robot viscosity field or the target’s motion (speed) was altered without any warning at the time of the Go cue. The viscosity could be increased which made it more difficult to …

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The Role Of Hostile And Benevolent Sexism On Women's Career Aspirations And Self-Doubt In Masculine And Feminine Majors, Mary Tait Oct 2021

The Role Of Hostile And Benevolent Sexism On Women's Career Aspirations And Self-Doubt In Masculine And Feminine Majors, Mary Tait

Master's Theses (2009 -)

Women experience hostile sexism and benevolent sexism in various aspects of their lives and the effects of these experiences have been shown to greatly affect their performance in career-related domains. Researchers have posited that this reduction in performance is related to self-doubt (Dardenne et al., 2007; Kuchynka et al., 2018) which can affect women’s careers long-term. However, the effects of self-doubt on women’s careers may vary depending on the stereotyped context of the environment. The current study examined if the relationship between experiences with sexism and career aspirations is mediated by self-doubt. Further, it was examined if the relationships changed …

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Assessment Of Mitochondrial Dysfunction In Lungs From Rats Exposed To Hyperoxia And The Efficacy Of Duroquinone, Swetha Ganesh Oct 2021

Assessment Of Mitochondrial Dysfunction In Lungs From Rats Exposed To Hyperoxia And The Efficacy Of Duroquinone, Swetha Ganesh

Master's Theses (2009 -)

Dissipation of mitochondrial membrane potential (ΔΨm) is a hallmark of mitochondrial dysfunction. The objective of this thesis was to use a previously developed experimental-computational approach to estimate tissue ΔΨm in intact lungs of rats exposed to hyperoxia, and to evaluate the ability of duroquinone (DQ) to reverse any hyperoxia-induced depolarization of lung Ψm. Rats were exposed to hyperoxia (>95% O2) or normoxia (room air) for 48 hrs, after which lungs were excised and connected to a ventilation-perfusion system. The experimental protocol consisted of measuring the concentration of the fluorescent dye rhodamine 6G (R6G) during three single-pass phases: loading, washing, …

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Crowdsourced Archiving Of The January 6th Us Capitol Insurrection: An R/Datahoarders Case Study, Edward Miezio Chapman Oct 2021

Crowdsourced Archiving Of The January 6th Us Capitol Insurrection: An R/Datahoarders Case Study, Edward Miezio Chapman

Master's Theses (2009 -)

The crowdsourced archiving that occurred in the wake of the January 6th US Capitol insurrection exemplifies the potential for agile, collaborative evidence gathering during a crisis situation. This paper studies the r/DataHoarders subcommunity of Reddit and the collective and spontaneous archiving project that users initiated. Users were drawn to the thread out of a desire to contribute to law enforcement efforts, enact punitive justice upon the rioters, engage in public discourse, and preserve information for posterity. They did this by gathering and preserving social media evidence that may have otherwise been lost. I discovered that this constituted a crowdsourced archive …

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Stochastic Modeling For Mobile Manipulators, Xie Jiayu Oct 2021

Stochastic Modeling For Mobile Manipulators, Xie Jiayu

Master's Theses (2009 -)

Mobile manipulators are valuable and highly desired in many fields, especially in industrial environments. However, determining the end effector position has been challenging for scenarios where the base moves at the same time that the arm follows commands to perform specific tasks. Earlier works have attempted to dynamically evaluate the problem of positioning error for mobile manipulators, but there is still room for further improvement. In this thesis, we devise a dynamical model that leverages stochastic search strategies for mobile manipulators. More specifically, we develop a dynamic model that estimates the position of the robot using an Unscented Kalman filter. …

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Detecting Invasive Insects Using Uncewed Aerial Vehicles And Variational Autoencoders, Scott Daniel Stewart Oct 2021

Detecting Invasive Insects Using Uncewed Aerial Vehicles And Variational Autoencoders, Scott Daniel Stewart

Master's Theses (2009 -)

In this thesis, we use machine learning techniques to address limitations in our ability to monitor pest insect migrations. Invasive insect populations, such as the brown marmorated stink bug (BMSB), cause significant economic and environmental damages. In order to mitigate these damages, tracking BMSB migration is vital, but it also poses a challenge. The current state-of-the-art solution to track insect migrations is called mark-release-recapture. In mark-release-recapture, a researcher marks insects with a fluorescent powder, releases them back into the wild, and searches for the insects using ultra-violet flashlights at suspected migration destination locations. However, this involves a significant amount of …

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Aeroacoustic Design Of An Abrasive Blasting Nozzle Using Cfd, Adam Dehli Oct 2021

Aeroacoustic Design Of An Abrasive Blasting Nozzle Using Cfd, Adam Dehli

Master's Theses (2009 -)

Current industrial abrasive blasting nozzles are often loud enough to negatively impact worker health and require employers to implement hearing conservation programs under OSHA noise exposure regulations. Significant opportunity exists for the use of modern computational fluid dynamics software (CFD) in the design of an abrasive blasting nozzle with a focus on reducing the acoustic intensity. Past work using CFD for abrasive blasting nozzle design has focused on improving productivity, ignoring aeroacoustic considerations. ANSYS Fluent software was used to investigate the effect of geometry changes to a commercially available No. 6 venturi nozzle, specifically the addition of a constant cross-section …

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Study Of Extensions To The Linear Sampling Method For Electromagnetic Inverse Scattering, Yeasmin Sultana Oct 2021

Study Of Extensions To The Linear Sampling Method For Electromagnetic Inverse Scattering, Yeasmin Sultana

Master's Theses (2009 -)

The linear sampling method (LSM) is a simple and effective qualitative method to reconstruct the support of unknown object by solving inverse scattering problem. The solution is done based on the field radiated by the elementary source located in a set of test points. In this thesis, the LSM formulation, limitations of standard LSM and extensions of LSM are discussed. Standard LSM can reconstruct simply connected objects, but it fails in case of concave or not simply connected objects. However, it can reconstruct the convex hull for such objects. Some extensions to LSM have been proposed to avoid these limitations. …

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La Migración Como Determinante De La Obesidad Infantil En Estados Unidos Y Latinoamérica, Mireya Vilar-Compte, Arturo V. Bustamante, Nancy López-Olmedo, Pablo Gaitán-Ross, Jaqueline Torres, Karen E. Peterson, Graciela Teruel, Rafael Pérez-Escamilla Oct 2021

La Migración Como Determinante De La Obesidad Infantil En Estados Unidos Y Latinoamérica, Mireya Vilar-Compte, Arturo V. Bustamante, Nancy López-Olmedo, Pablo Gaitán-Ross, Jaqueline Torres, Karen E. Peterson, Graciela Teruel, Rafael Pérez-Escamilla

Department of Public Health Scholarship and Creative Works

La migración internacional tiene consecuencias económicas y en la salud. El proceso de aculturación en el país de acogida puede estar relacionado con la obesidad infan-til. Utilizamos el marco conceptual del balance energético comunitario (CEB, por sus siglas en inglés) para analizar la relación entre migración y obesidad infantil en los hogares mexicanos con migrantes internacionales. Utilizando datos longitudinales de la Encuesta Nacional de Niveles de Vida de los Hogares de México (ENNViH), exami-namos cómo influyen las redes de migrantes sobre la obesidad infantil en las comuni-dades de origen. También revisamos programas de salud binacionales que podrían ser eficaces para …

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Micromechanics Of Additively Manufactured Materials Under Dynamic Loading, Christopher Rueben Johnson Oct 2021

Micromechanics Of Additively Manufactured Materials Under Dynamic Loading, Christopher Rueben Johnson

Dissertations (1934 -)

Ongoing works aim to develop a predictive computational framework whichcan be utilized to shorten the design and certification cycle of additively manufactured (AM) 304L stainless steel (SS304L). High fidelity experiments are utilized to validate and parameterize the computational framework. Results have detailed differing mechanical responses across a breadth of strain rates for wrought and AM SS304L. Differences are attributed to the microstructural properties resulting from the fabrication and treatment of the materials. This work aims to supplement preexisting high strain rate compressive strength experimental data sets to further quantify process-structure-property (PSP) relationships in development of the computational framework. Materials investigated …

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Direct And Non-Invasive Monitoring Of Battery Internal State Via Novel Gmi-Idt Magnetic Sensor, Akila Khatun Oct 2021

Direct And Non-Invasive Monitoring Of Battery Internal State Via Novel Gmi-Idt Magnetic Sensor, Akila Khatun

Dissertations (1934 -)

Efficient battery management systems (BMSs) in rechargeable battery-based systems require precise measurements of various battery parameters including state of charge (SOC), state of health (SOH) and charge capacity. Presently, SOC, charge capacity and SOH can only be indirectly inferred from long-term measurement of current, open circuit voltage (OCV), and temperature using multiple sensors. These techniques can only give an approximation of SOC and often require knowledge of the recent battery history to prevent excessive inaccuracy.To improve the performance of the BMS, an alternative method of monitoring the internal state of Li-ion batteries is presented here. Theoretical analysis of Li-ion batteries …

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A Novel Laser-Aided Machining And Polishing Process For Additive Manufacturing Materials With Multiple Endmill Emulating Scan Patterns, Mohammad Masud Parvez, Sahil Patel, Sriram Praneeth Isanaka, Frank W. Liou Oct 2021

A Novel Laser-Aided Machining And Polishing Process For Additive Manufacturing Materials With Multiple Endmill Emulating Scan Patterns, Mohammad Masud Parvez, Sahil Patel, Sriram Praneeth Isanaka, Frank W. Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

In additive manufacturing (AM), the surface roughness of the deposited parts remains significantly higher than the admissible range for most applications. Additionally, the surface topography of AM parts exhibits waviness profiles between tracks and layers. Therefore, post-processing is indispensable to improve surface quality. Laser-aided machining and polishing can be effective surface improvement processes that can be used due to their availability as the primary energy sources in many metal AM processes. While the initial roughness and waviness of the surface of most AM parts are very high, to achieve dimensional accuracy and minimize roughness, a high input energy density is …

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Tying A Tribal Officer's Hands: Tribal Law Enforcement Authority Under United States V. Cooley, Mikaela Koski Oct 2021

Tying A Tribal Officer's Hands: Tribal Law Enforcement Authority Under United States V. Cooley, Mikaela Koski

Penn State Law Review (2003 - Present)

No abstract provided.

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Survivability Analysis In The Shadow Of Apollo: Part I - Cislunar Debris Propagation And Spacecraft Vulnerability, Nathan R. Boone, Robert A. Bettinger Oct 2021

Survivability Analysis In The Shadow Of Apollo: Part I - Cislunar Debris Propagation And Spacecraft Vulnerability, Nathan R. Boone, Robert A. Bettinger

Faculty Publications

Although the reality of routine travel and sustained operations and habitation in space likely remains several decades away, the building blocks of space exploration and space system development necessary to realize this reality are currently being laid by peer, near-peer, and emerging space-faring nations. Traditionally, global space operations were notionally limited to near-Earth space, with mission altitudes extending to geosynchronous or even highly elliptical orbits. During the 2010s, however, space operations began moving beyond this paradigm to encompass cislunar space with reinvigorated U.S. initiatives to return to the Moon via the Artemis program, planned commercial space projects, and an accelerated …

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Immunomodulatory Activity Of Carboxymethyl Pachymaran On Immunosuppressed Mice Induced By Cyclophosphamide, Feng Liu, Lijia Zhang, Xi Feng, Salam A. Ibrahim, Wen Huang, Ying Liu Oct 2021

Immunomodulatory Activity Of Carboxymethyl Pachymaran On Immunosuppressed Mice Induced By Cyclophosphamide, Feng Liu, Lijia Zhang, Xi Feng, Salam A. Ibrahim, Wen Huang, Ying Liu

Faculty Research, Scholarly, and Creative Activity

The effects of immunomodulatory activity of two types of carboxymethyl pachymaran (CMP-1 and CMP-2) on cyclophosphamide (CTX)-induced mice were investigated. Both CMP-1 and CMP-2 were found to restore the splenomegaly and alleviate the spleen lesions and the mRNA ex-pressions of TLR4, MyD88, p65 and NF-κB in spleen were also increased. CMP-1 and CMP-2 could enhance the immunity by increasing the levels of TNF-α, IL-2, IL-6, IFN-γ, Ig-A and Ig-G in serum. In addition, CMP-1 could increase the relative abundance of Bacteroidetes and reduce the relative richness of Firmicutes at the phylum level. CMP-1 and CMP-2 could reduce the relative abundance …

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Meridians 20:2 Transnational Feminist Approaches To Anti-Muslim Racism, Ginetta Candelario Oct 2021

Meridians 20:2 Transnational Feminist Approaches To Anti-Muslim Racism, Ginetta Candelario

Meridians: Feminism, Race, Transnationalism

This issue coincides with the twentieth anniversary of the United States’ initiation of the “war on terror” launched in the aftermath of the events of September 11, 2001. On that day, al-Qaeda operatives destroyed the World Trade Center in lower Manhattan by flying two hijacked planes into the twin towers; a third hijacked plane hit the first floor of the Pentagon’s west wall; and a fourth plane crashed in a field in Shanksville, Pennsylvania when passengers successfully thwarted the hijackers....

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Chairs Of Excellence Annual Report 2021, Tennessee. Higher Education Commission. Oct 2021

Chairs Of Excellence Annual Report 2021, Tennessee. Higher Education Commission.

Academic Programs and Workforce Reports

No abstract provided.

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Guide For Teaching Faculty 2021-2022, Ceteal, Coastal Carolina University Oct 2021

Guide For Teaching Faculty 2021-2022, Ceteal, Coastal Carolina University

Guide for Teaching Faculty

No abstract provided.

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High-Throughput Next-Generation Sequencing Respiratory Viral Panel: A Diagnostic And Epidemiologic Tool For Sars-Cov-2 And Other Viruses, Nikhil S. Sahajpal, Ashis K. Mondal, Allan Njau, Zachary Petty, Jiani Chen, Sudha Ananth, Pankaj Ahluwalia, Colin Williams, Ted M. Ross, Alka Chaubey Oct 2021

High-Throughput Next-Generation Sequencing Respiratory Viral Panel: A Diagnostic And Epidemiologic Tool For Sars-Cov-2 And Other Viruses, Nikhil S. Sahajpal, Ashis K. Mondal, Allan Njau, Zachary Petty, Jiani Chen, Sudha Ananth, Pankaj Ahluwalia, Colin Williams, Ted M. Ross, Alka Chaubey

Pathology, East Africa

Two serious public health challenges have emerged in the current COVID-19 pandemic namely, deficits in SARS-CoV-2 variant monitoring and neglect of other co-circulating respiratory viruses. Additionally, accurate assessment of the evolution, extent, and dynamics of the outbreak is required to understand the transmission of the virus. To address these challenges, we evaluated 533 samples using a high-throughput next-generation sequencing (NGS) respiratory viral panel (RVP) that includes 40 viral pathogens. The performance metrics revealed a PPA, NPA, and accuracy of 95.98%, 85.96%, and 94.4%, respectively. The clade for pangolin lineage B that contains certain distant variants, including P4715L in ORF1ab, Q57H …

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