Digital Commons Network^™

Law Graduate Receives National Student Leadership Award, Christina Steube

University of Mississippi News

Julio Cazares recognized by the National LGBTQ+ Bar Association

Project Earthrise: Proceedings Of The Ninth Annual Conference Of Invivo Planetary Health, Susan L. Prescott, Ganesa Wegienka, Remco Kort, David H. Nelson, Sabine Gabrysch, Trevor Hancock, Anita Kozyrskyj, Christopher A. Lowry, Nicole Redvers, Blake Poland, Jake Robinson, Jean-Claude Moubarac, Sara Warber, Janet Jansson, Aki Sinkkonen, John Penders, Susan Erdman, Ralph Nanan, Matilda Van Den Bosch, Kirk Schneider, Nicholas J. Schroeck, Tanja Sobko, Jamie Harvie, George A. Kaplan, Rob Moodie, Laura Lengnick, Isaac Prilleltensky, Yuria Celidwen, Susan H. Berman, Alan C. Logan, Brian Berman

Public Health Sciences Articles

The "Earthrise" photograph, taken on the 1968 Apollo 8 mission, became one of the most significant images of the 20th Century. It triggered a profound shift in environmental awareness and the potential for human unity-inspiring the first Earth Day in 1970. Taking inspiration from these events 50 years later, we initiated

Ebux Of Oers For Ptc: Student And Faculty Ebook User Experiences (Ebux) Of Open Educational Resources (Oers) For Professional And Technical Communication (Ptc), Henry Covey

English Faculty Publications and Presentations

This report analyzes the digital/electronic textbook user experience (eBUX) of web-based open educational resources (OERs) for professional and technical communication (PTC). Data and information were gathered from students enrolled in introductory PTC courses (with IRB oversight and input from faculty and writing program directors) via online surveys (Google Forms), collaborative documents (Google Docs), remote interviews (Zoom), learning management system analytics (Desire2Learn), workshop documentation (pre-pandemic), and email correspondence. User research revealed issues of use and usability with web-based open-access PTC textbooks related to functional specifications, content requirements, interface and interaction design, information architecture, navigation, and aesthetics. The conclusion discusses the evolution …

Biophysical Evaluation Of Rhesus Macaque Fc Gamma Receptors Reveals Similar Igg Fc Glycoform Preferences To Human Receptors, Andrew R. Crowley, Nana Yaw Osei-Owusu, Gillian Dekkers, Wenda Gao, Manfred Wuhrer, Diogo M. Magnani, Keith A. Reimann, Seth H. Pincus, Gestur Vidarsson, Margaret E. Ackerman

Dartmouth Scholarship

Rhesus macaques are a common non-human primate model used in the evaluation of human monoclonal antibodies, molecules whose effector functions depend on a conserved N-linked glycan in the Fc region. This carbohydrate is a target of glycoengineering efforts aimed at altering antibody effector function by modulating the affinity of Fcγ receptors. For example, a reduction in the overall core fucose content is one such strategy that can increase antibody-mediated cellular cytotoxicity by increasing Fc-FcγRIIIa affinity. While the position of the Fc glycan is conserved in macaques, differences in the frequency of glycoforms and the use of an alternate monosaccharide in …

Luminescence Complementation Technology For The Identification Of Myc:Trrap Inhibitors, Edmond J. Feris, John W. Hinds, Michael D. Cole

Dartmouth Scholarship

Mechanism-based targeted therapies have exhibited remarkable success in treating otherwise untreatable or unresectable cancers. Novel targeted therapies that correct dysregulated transcriptional programs in cancer are an unmet medical need. The transcription factor MYC is the most frequently amplified gene in human cancer and is overexpressed because of mutations in an array of oncogenic signaling pathways. The fact that many cancer cells cannot survive without MYC - a phenomenon termed "MYC addiction" - provides a compelling case for the development of MYC-specific targeted therapies. We propose a new strategy to inhibit MYC function by disrupting its essential interaction with TRRAP using …

Webinar: The Impact Of Transportation-Related Barriers On Self-Perceived Physical Health Among Adults In The Us, Philip Baiden, Godfred Boateng

TREC Webinar Series

Drawing from the framework of social determinants of health, the objective of this study is to investigate the cross-sectional association between transportation-related factors and self-perceived physical health among adults in the U.S.

Data for this study were derived from the 2017 National Household Travel Survey. An analytic sample of 71,235 respondents aged 18 and 64 years was analyzed using binary logistic regression. Of the 71,235 respondents examined, 8.9% perceived their physical health to be poor. About 36% of the respondents had fewer vehicles per individuals in the household.

Controlling for the effects of other factors, respondents who had fewer vehicles …

Zero-Bias Deep Neural Network For Quickest Rf Signal Surveillance, Yongxin Liu, Jian Wang, Dahai Liu, Houbing Song, Yingjie Chen, Shuteng Niu

Publications

The Internet of Things (IoT) is reshaping modern society by allowing a decent number of RF devices to connect and share information through RF channels. However, such an open nature also brings obstacles to surveillance. For alleviation, a surveillance oracle, or a cognitive communication entity needs to identify and confirm the appearance of known or unknown signal sources in real-time. In this paper, we provide a deep learning framework for RF signal surveillance. Specifically, we jointly integrate the Deep Neural Networks (DNNs) and Quickest Detection (QD) to form a sequential signal surveillance scheme. We first analyze the latent space characteristic …

Biophysical Evaluation Of Rhesus Macaque Fc Gamma Receptors Reveals Similar Igg Fc Glycoform Preferences To Human Receptors, Andrew R. Crowley, Nana Yaw Osei-Owusu, Gillian Dekkers, Wenda Gao, Manfred Wuhrer, Diogo M. Magnani, Keith A. Reimann, Seth H. Pincus, Gestur Vidarsson, Margaret E. Ackerman

School of Medicine Faculty Publications

Rhesus macaques are a common non-human primate model used in the evaluation of human monoclonal antibodies, molecules whose effector functions depend on a conserved N-linked glycan in the Fc region. This carbohydrate is a target of glycoengineering efforts aimed at altering antibody effector function by modulating the affinity of Fcγ receptors. For example, a reduction in the overall core fucose content is one such strategy that can increase antibody-mediated cellular cytotoxicity by increasing Fc-FcγRIIIa affinity. While the position of the Fc glycan is conserved in macaques, differences in the frequency of glycoforms and the use of an alternate monosaccharide in …

Assessing The Success Of The 2020 Kansas State Research And Extension Summer Research Program: A Virtual Research Experience, Lonnie Hobbs, Jr., Zelia Z. Wiley, Raymond Thomas

Professional Agricultural Workers Journal

Ethnic minorities, and specifically African American students are not participating in graduate programs at the same rate as non-minority students. In 2006, Kansas State University College of Agriculture Diversity Programs Office (DPO) established the Kansas State Research and Extension (KSRE) Summer Research Fellows Program to expose African American and other ethnic minority students to the agricultural sciences graduate research opportunities. Due to the Covid-19 pandemic, the 2020 KSRE Summer Research Fellows Program was held virtually to protect the health and safety of participants. The purpose of this study was to evaluate the effectiveness of the virtual program. Data from five …

Expression, Purification And Refolding Of A Human Na V 1.7 Voltage Sensing Domain With Native-Like Toxin Binding Properties, Ryan V. Schroder, Leah S. Cohen, Ping Wang, Joekeem D. Arizala, Sébastien F. Poget

Publications and Research

The voltage-gated sodium channel NaV1.7 is an important target for drug development due to its role in pain perception. Recombinant expression of full-length channels and their use for biophysical characterization of interactions with potential drug candidates is challenging due to the protein size and complexity. To overcome this issue, we developed a protocol for the recombinant expression in E. coli and refolding into lipids of the isolated voltage sensing domain (VSD) of repeat II of NaV1.7, obtaining yields of about 2 mg of refolded VSD from 1 L bacterial cell culture. This VSD is known to be involved in the …

Ucc Minutes, October 12, 2021, University Curriculum Council

UCC Agendas/Minutes

No abstract provided.

Niche Applications And Flexible Devices For Wave Energy Conversion: A Review, Emiliano Renzi, Simone Michele, Siming Zheng, Siya Jin, Deborah Greaves

School of Engineering, Computing and Mathematics

We review wave energy conversion technologies for niche applications, i.e., kilowatt-scale systems that allow for more agile design, faster deployment and easier operation than utility scale systems. The wave energy converters for niche markets analysed in this paper are classified into breakwater-integrated, hybrid, devices for special applications. We show that niche markets are emerging as a very vibrant landscape, with several such technologies having now achieved operational stage, and others undergoing full-scale sea trials. This review also includes flexible devices, which started as niche applications in the 1980s and are now close to commercial maturity. We discuss the strong potential …

Interview With Greg Kieffer, Greg Kieffer, Aaron Cervantez, Leslie Torres, Stephanie Medellin

Community Historical Archaeology Project with Schools (CHAPS) Oral Histories

No abstract provided.

Advancing Behavioral Health Literacy, James Scollione

Journal of Social, Behavioral, and Health Sciences

Accessing, comprehending, and using information to make informed decisions and improve one’s overall health or well-being are the foci of health literacy. The concept of behavioral health was introduced in the early 1980s and, since then, it has influenced new ideas (e.g., behavioral health literacy and integrated behavioral health care) and gained research and public attention. My aim is to provide an overview of definitions (i.e., health literacy, mental health literacy, and behavioral health literacy) and their connection to each other. I propose an expanded and honed definition of behavioral health literacy to enhance the behavioral health literacy and well-being …

Who Do College Students Turn To For Financial Aid And Student Loan Advice, And Is It Advice Worth Following?, Casandra E. Harper, Lisa Scheese, Enyu Zhou, Rajeev Darolia

Journal of Student Financial Aid

In this article, we examine the sources of information that college students turn to as they make decisions related to financial aid and student loans. Based on interview data from 25 undergraduate students from one public, four-year institution, our results reveal a great amount of variation in the number and nature of sources on which students rely. Across nearly all cases, students believed their access to assistance to be insufficient. This was true even for students with parents who attended college—commonly considered to be a high-quality source of support for students, when available—as students often found their advice outdated, confusing, …

Hidden Inequality: Financial Aid Information Available To College Students With Disabilities Attending Public Four-Year Institutions, Emily L. Perlow, Ryan S. Wells, Mujtaba Hedayet, Jenny Xia, Heather Maclean, Emily Ding, Angela Mccall

Journal of Student Financial Aid

College students with disabilities often encounter systems and processes that do not serve them well. Financial aid, structured in ways that can be particularly burdensome to students with disabilities, is one such system. This study used web-based content analysis of the largest public four-year institution in each state to explore how institutions explain and provide information and resources related to financial aid and whether they are equitable, consistent, and useful for students with disabilities specifically. The findings suggest that available information most often does not assist students in understanding how their disability-related needs can be supported or hindered by financial …

Criteria And Standards For Healthcare Buildings Design Through Sustainability Criteria., Ahmed El Deep, Sherif Sheta, Wael Moustafa

Mansoura Engineering Journal

Increased interest in providing health care services at all levels through the understanding of modern societies of the importance of good health of the individual and society health is as defined by the World Health Organization "WHO" World Health Organization is a state integration between the three elements physical, psychological and social" , In the past, the idea of health care facilities and hospitals rely on something to offer the services of the hos[ital., but the modern from New Paradigms. It is based on the requirements of the patient and confort. We find in the new model for building health …

Urban Areas Development Through The Process Of Environmental Impact Assessment., Riyadh Alshamiri

Mansoura Engineering Journal

The research aims to describe and analyze the environmental impact Assessment of urban areas, and to identify deficiencies that emerges from the environmental impact Assessment process, and access to the expected solutions of Environmental Impact Assessment System in the urban areas development. To achieve the aim of research and through the analytical method, the search begins by giving a theoretical background for environmental impact Assessment and the urban areas development. Then identify the gaps of environmental impact Assessment process in the urban area development and expected solutions from this process. Eventually, the paper provides a number of findings and recommendations …

Characteristics Of Plan Poiseuille Flows Under The Effect Of Electro-Magnetics Fields., A. El-Zahaby, M. Bassiouny, A. Khalil, E. El-Shenawy, E. El-Agouz, M. Amro

Mansoura Engineering Journal

The fully developed flow between two parallel plates in an electrically conducting fluid under the acting of electromagnetic fields is solved analytically. The value of flow rate. Velocity. Share stress and skin friction coefficient at the plates are derived. It is noticed that the electromagnetic forces are able to derive the flow in the absence of the pressure gradient also; the flow characteristics are largely changed when the electromagnetic fields are applied in the presence of the pressure gradient. The change in velocity. Shear stress and skin friction coefficient are represented as a function of the geometrical ratio between the …

Collagen-Based Biomaterials With Possible Therapeutic Effects, Ramona Mihaela Nedelcuţă, Gigi Călin, Mihai Cristian Nedelcuţă, Vlad Dumitru Baleanu, Dragos Virgil Davitoiu, Bogdan Socea, Bogdan-Petre Stănoiu

Journal of Mind and Medical Sciences

Epidermolysis bullosa (EB) is a rare, serious genetic disease, incurable through the current means. Apart from this initial definition, there was later some ease in the definition of the disease, including the manifestations of toxic epidermal necrolysis and Stevens Johnson syndrome in this entity. In medical practice, there are cases that do not overlap with the description in the literature, thus the treatment must be adapted and personalized to the particularities. We present the case of a female new-born, with "de novo" mutation for the early-onset antenatal epidermolysis and our personalized therapeutic management, based on collagen from bovine corneas by …

Therapeutic Efficacy Of Mesenchymal Stem Cells For Cardiovascular Diseases, Dragana Radoje Miloradovic, Dragica Radoje Pavlovic, Miodrag Bozidar Stojkovic, Sanja Bratislav Bojic, Vladislav Bogdan Volarevic, Marina Milosav Gazdic Jankovic, Biljana Tomislav Ljujic

Journal of Mind and Medical Sciences

Despite the improvements in pharmacological and surgical treatments, cardiovascular diseases (CVDs) are the number one cause of death worldwide. During the last two decades, the search for new therapies has been revolutionized with the growing knowledge of stem cell biology. Due to their huge differentiation capacity and paracrine effects, mesenchymal stem cells (MSCs) are a promising tool for the treatment of CVDs. The encouraging outcomes of preclinical studies using MSCs as a treatment for diseased myocardium have set the scene for worldwide clinical trials. In this review, we overview either complete or ongoing clinical trials using MSCs for the therapy …

Ai, Ml, And Algorithms, Oh My: How Technology Affects Search Results, Marydee Ojala

Midwest Business Librarian Summit (MBLS)

AI, ML, and Algorithms, Oh My: How Technology Affects Search Results

There’s no doubt that artificial/augmented intelligence, machine learning, and algorithms affect your search results. Most business researchers understand that their web searches are influenced by the underlying technologies and that the algorithms in play are numerous and not disclosed by search engine companies. However, AI is also used by our library subscription databases—you know, the ones we pay money for. Learn the five basic things you should know about the effect of these technologies on your search results.

Jim Murry Memorial Memory Book, Evan Barrett

Supplementary Materials

Booklet remembering the legacy of Jim Murry.

Ada News - 10/11/2021, American Dental Association, Publishing Division

ADA News

Established in 1970 as the official newspaper of the American Dental Association, the ADA News serves practicing dentists and others allied to the dental profession in the U.S. and internationally. It is the No. 1 source of news and information about the many benefits and services the ADA delivers to members daily as well as timely information on scientific, social, political and economic developments affecting dentistry and health care.

The Echo: October 11, 2021, Taylor University

2021-2022 (Volume 109)

Taylor names new provost, VP of marketing — Mask mandate lifts while vaccine rate sits at 35% — Upland grant to grow downtown — New intercultural resources available online — Dairy Queen coming to Gas City — Unified Robotics Championship to be held at Taylor — A sneak peek into Walnut Creek Market — Josiah Friesen shares his music composition process — We love the DC staff — Support your peers at shop the loop — This may be the best advice you’ve been given — Smith pursues music career while being a full-time student — Art departments previews showcases …

Human 5’-Tailed Mirtrons Are Processed By Rnasep, Mohammad Farid Zia

Dissertations

Approximately a thousand microRNAs (miRNAs) are documented from human cells. A third appear to transit non-canonical pathways that typically bypass processing by Drosha, the dedicated nuclear miRNA producing enzyme. The largest class of non-canonical miRNAs are mirtrons which eschew Drosha to mature through spliceosome activity. While mirtrons are found in several configurations, the vast majority of human mirtron species are 5’-tailed. For these mirtrons, a 3’ splice site defines the 3’ end of their hairpin precursor while a “tail” of variable length separates the 5’ base of the hairpin from the nearest splice site. How this tail is removed is …

Executive Committee Resolution Sr 21-22-01, Marshall University Faculty Senate

Resolutions

No abstract provided.

Multi-Organs-On-Chips For Testing Small-Molecule Drugs: Challenges And Perspectives., Berivan Cecen, Christina Karavasili, Mubashir Nazir, Anant Bhusal, Elvan Dogan, Fatemeh Shahriyari, Sedef Tamburaci, Melda Buyukoz, Leyla Didem Kozaci, Amir K Miri

Henry M. Rowan College of Engineering Departmental Research

Organ-on-a-chip technology has been used in testing small-molecule drugs for screening potential therapeutics and regulatory protocols. The technology is expected to boost the development of novel therapies and accelerate the discovery of drug combinations in the coming years. This has led to the development of multi-organ-on-a-chip (MOC) for recapitulating various organs involved in the drug-body interactions. In this review, we discuss the current MOCs used in screening small-molecule drugs and then focus on the dynamic process of drug absorption, distribution, metabolism, and excretion. We also address appropriate materials used for MOCs at low cost and scale-up capacity suitable for high-performance …

What Kind Of Information Does The Era Of Climate Change Require?, Jo Guldi

History Faculty Publications

This article explores the promise of institutions and infrastructures associated with democ- racy to limit the worst consequences of climate change. The article highlights the appar- ent conflict between expert governance on the one hand, and, on the other hand, calls for democratization that reflect the diverse perspectives of groups whose rights and labor have been exploited over historical timescales. Drawing on the history of bureaucracy and governance, this article argues that the apparent contradiction between the two poles of discourse can be reconciled by a system of information infrastructure designed to cre- ate a robust, accountable system of environmental …

Uncovering Disease Mechanisms In A Novel Mouse Model Expressing Humanized Apoeε4 And Trem2*R47h., Kevin P Kotredes, Adrian Oblak, Ravi S Pandey, Peter Bor-Chian Lin, Dylan Garceau, Harriet M. Jackson, Asli Uyar, Rita O'Rourke, Sarah O'Rourke, Cynthia Ingraham, Daria Bednarycek, Melisa Belanger, Zackary Cope, Kate E Foley, Benjamin A Logsdon, Lara M Mangravite, Stacey J Sukoff Rizzo, Paul R Territo, Gregory W. Carter, Michael Sasner, Bruce T Lamb, Gareth R Howell

Faculty Research 2021

Late-onset Alzheimer's disease (AD; LOAD) is the most common human neurodegenerative disease, however, the availability and efficacy of disease-modifying interventions is severely lacking. Despite exceptional efforts to understand disease progression via legacy amyloidogenic transgene mouse models, focus on disease translation with innovative mouse strains that better model the complexity of human AD is required to accelerate the development of future treatment modalities. LOAD within the human population is a polygenic and environmentally influenced disease with many risk factors acting in concert to produce disease processes parallel to those often muted by the early and aggressive aggregate formation in popular mouse …