Digital Commons Network^™

Mechanisms Of Synergy Between Nanosecond Pulsed Electric Field (Nspef) And Cold Atmospheric Pressure Plasma Discharge (Cap) In Pancreatic Cancer: The Role Of Ros-Mediated Oxidative Stress And Apoptosis, Zobia Minhas

Biomedical Sciences Theses & Dissertations

Pancreatic ductal adenocarcinoma is a highly lethal malignancy characterized by poor prognosis and resistance to conventional therapies. Novel treatment strategies are needed to overcome this resistance. Non-thermal physical modalities, including nanosecond pulsed electric field (nsPEF) and cold atmospheric pressure plasma discharge (CAP), have emerged as potential anticancer approaches; however, the mechanisms underlying their combined effects remain unclear.

This study evaluated whether nsPEF enhances CAP-induced cytotoxicity and investigated the associated molecular mechanisms using the murine Pan02 pancreatic cancer cell line. Cell viability was assessed by WST-1 metabolic activity assays and electric cell–substrate impedance sensing (ECIS). Intracellular reactive oxygen species (ROS) were …

Llms-Based Text-To-Sql For Geospatial Information Retrieval, Temitayo Olamilekan Ogunsusi

All Theses

Text-to-SQL aims to translate natural language questions into SQL queries that can be executed on databases, enabling non-expert users to retrieve information without learning formal query languages. Early Text-to-SQL systems relied on rule-based methods and semantic parsers, while recent advances in deep learning have achieved strong performance by jointly encoding user questions and database schemas. However, these approaches typically require large, annotated datasets and specific model architectures. With the emergence of large language models (LLMs), such as GPT-4, Llama, and Gemma, Text-to-SQL systems can leverage powerful natural language understanding capabilities to generate SQL queries using zero-shot or few-shot prompting. Despite …

Multi-Task Growing Interpretable Neural Network For Multi-Target Symbolic Regression, Hussein Rajabu

All Theses

Over the past decade, deep learning has achieved remarkable success across domains such as computer vision and natural language processing. Despite their strong predictive capabilities, these models often function as black boxes, limiting transparency and making them difficult to trust in high-stakes applications such as healthcare and business decision-making. While explainable artificial intelligence (XAI) methods improve interpretability, most approaches remain post-hoc, focusing on statistical associations rather than uncovering the underlying functional mechanisms governing predictions.

Symbolic regression (SR) has emerged as a promising direction within XAI by directly discovering explicit mathematical expressions that describe relationships between inputs and outputs. Unlike traditional …

The Effect Of Social Media On The Growth Of Animal Shelters And Rescue Programs, Viktoria Schmidt

Marketing Undergraduate Honors Theses

The landscape of animal welfare in the United States is currently navigating a period of structural transformation, moving from a reactive “holding” model toward a proactive “community resource” model. They are becoming an assistive safety net rather than just a physical “cell” for these animals. They had no choice but to focus on space, however they’ve transitioned towards open communication to create a relationship with onlookers. As of 2026, the industry faces a complex capacity crisis; while 2025 marked the first significant decrease in shelter euthanasia since the pandemic, an 8.1% drop, approximately 5.8 million animals continue to enter the …

Exclusive By Design: Engineered Scarcity And Consumer Behavior In Fashion Drops, Caroline H. Meyer

Marketing Undergraduate Honors Theses

The drop business model centers on releasing small batches of products, often without much notice, on a recurring or semi-regular schedule. These limited releases, or "drops," sell out quickly and rarely restock, creating urgency and making each product feel exclusive. Consumers are trained to anticipate launches, check for updates, and act fast within minutes to secure items before they’re gone. By tapping into psychological drivers such as scarcity, fear of missing out (FOMO), and the desire for social belonging, the drop model flips traditional retail logic. Instead of keeping shelves full, it withholds. Instead of lowering prices to drive sales, …

The Political Transformation Of Corporate America, 2001–2022, Reilly S. Steel

Faculty Scholarship

This article reconciles conflicting views about the political landscape of corporate America with new data on the revealed political preferences of 97,469 corporate directors and executives at 9,005 different U.S. companies. Driven largely by turnover, I find that average observed ideology for directors and executives has shifted meaningfully to the left over time, changing from modestly conservative in 2001 to roughly centrist by 2022. This finding supports a middle-ground position between conventional wisdom casting “big business” as a conservative stronghold and revisionist views holding the opposite. Counterfactual simulations and a difference-in-differences design suggest multifaceted reasons for these changes, and hand-collected …

Enameling Coating Of Pipes: Thermal Proprieties And Corrosion Tests, Signo Reis, Genda Chen, Mike Koenigstein, Liang Fan

Materials Science and Engineering Faculty Research & Creative Works

Enamel coating on pipelines can be done in several ways such as the wet process, plasma spray, and electrostatic process. Wet process requires little capital expenses and provides an acceptable finish for industrial applications particularly when the part to be coated is small. Electrostatic process of enamel powder is most promising to coating large pipelines in field conditions. The enamel coating applied by the electrostatic process is very consistent and smooth since each particle is glass only. However, the powder is very fragile until fired and the charge retention is lowered in high humidity conditions. Coupons cut from a full-size …

Effect Of Environmental Conditions On Fracture Of Composite Materials And Thin Films, Victor Birman

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Environmental conditions, i.e., temperature and moisture, affect mechanical properties of materials, including composites. In this paper, we concentrate on one of the aspects of the effect of environment on fracture in a composite lamina. The paper demonstrates an analytical approach to account for the effect of the changes in environment on the strain energy release rate of composite materials and thin films. These analytically determined strain energy release rates should be compared to fracture toughness to predict the susceptibility of the material to fracture. Numerical examples are presented for several polymeric and metal matrix composites using available experimental data for …

Validity Of The Schrage Equation In Prediction Of Evaporation Rate Of Liquid N-Dodecane In High-Pressure Nitrogen Gas: A Molecular Dynamics Study, Wazih Tausif, Jordan Hartfield, Md Amin Haque, Zhi Liang

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Evaporation of liquid fuel in a high-pressure air is a process that critically influences fuel–air mixing in advanced propulsion systems. In this work, we use molecular dynamics (MD) simulations to study the validity and accuracy of the Schrage equation in quantifying the evaporation and condensation rates of n-dodecane (a diesel surrogate) in air (approximated as N2 gas) with gas pressure varying from 0 atm to above the critical pressure of n-dodecane. The MD simulation results show that the evaporation coefficient (αe) is higher than the condensation coefficient (αc) at the evaporating n-dodecane surface and is lower than αc at the …

A Federated Learning Framework For Data-Sovereign Predictive Maintenance In Distributed Smart Manufacturing, Md Sazol Ahmmed, Sriram Praneeth Isanaka, Frank Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

Featured Application: The proposed federated learning framework can be applied in distributed smart manufacturing environments where multiple factories or production facilities collaboratively develop predictive maintenance models without sharing sensitive operational data. This approach is particularly useful for industrial networks involving geographically distributed plants, contract manufacturing partners, and multi-site production systems where data sovereignty and avoidance of raw data sharing are critical. Predictive maintenance enables early detection of machine failures and reduces unexpected production downtime. However, conventional approaches typically rely on centralized data collection and model training which introduce challenges related to data sovereignty, communication overhead and data ownership. To address …

Measurements And Scaling Of Ion Propulsion Impulse During Driven Magnetic Reconnection, Fatima Ebrahimi, Nicholas A. O'Gorman, Kush Maheshwari, Jongsoo Yoo, Alexandre Sainterme, Hantao Ji

Faculty Publications

Impulse scaling during magnetic reconnection, the magnetic energy conversion to kinetic energy, via direct Mach probe measurements in Magnetic Reconnection Experiment is examined. Ion exhaust velocity and impulse scalings with reconnecting magnetic field during the push phase of driven reconnection are presented. The outflows and impulse measurements are compared with global MHD simulations. Both measurements and simulations reveal a favorable scaling, greater than linear, of impulse with reconnecting field. These scaling results establish that magnetic reconnection could be utilized for plasma propulsion.

Low Methane Emissions From Nutrient-Rich Former River Channels In A Hydrologically Managed Dryland Delta, Siena Stassi, Jude A. Benavides, Chu-Lin Cheng, Marcelo Gomes Da Silva, Nicholas E. Ray, Nathan O. Barros, Rafael M. Almeida

School of Earth, Environmental, & Marine Sciences Faculty Publications

Anthropogenic stresses in dryland regions can alter hydrology, salinization, and biogeochemical processes. How these pressures influence methane (CH4) cycling and emissions from aquatic ecosystems remains poorly understood. Over the course of 1 year, we measured diffusive and ebullitive CH4 emissions from resacas—shallow, hydrologically managed distributary channels prevalent throughout the Lower Rio Grande Valley along the US–Mexico border. Despite warm, nutrient-rich waters, CH4 emissions from resacas were low, and more comparable to rates observed in estuarine systems. CH4 fluxes were positively related to temperature but negatively related to salinity and rainfall. Elevated salinity, driven by evaporation and source water from the …

Advanced Optimization And Integration Of Propellant Flow Path For Cntr Fuel Tube, David Cox, Michael Rietze, Karl Lauture, Max Lowe, Elijah Spencer, Kojo Pinkrah

Mechanical Engineering Capstone Design Projects

The Centrifugal Nuclear Thermal Rocket (CNTR) is an advanced propulsion concept whose performance is strongly influenced by the efficiency and continuity of its propellant flow path. This project focuses on improving the geometric integrity and analytical fidelity of the CNTR fuel tube inlet and manifolds, which are critical subsystems governing pressure losses and downstream performance. In prior designs, these parts consisted of multiple components assembled using adhesive, introducing geometric discontinuities that increased head losses and limited the reliability of computational analysis.

In this work, the inlet and manifold were successfully redesigned as single, integrated components. This redesign represents a key …

A Critical Review And Methodological Recommendations For Life Cycle Assessment Of Electrochemical Co₂ Mineralization, Dennis Dadzie, Kwame Awuah-Offei

Mining Engineering Faculty Research & Creative Works

Purpose: While researchers have relied on life cycle assessments (LCAs) to make claims about the environmental benefits of electrochemical CO₂ mineralization, no systematic review literature exists that synthesizes what we know about the LCA of electrochemical mineralization. This review aims to synthesize established knowledge on the LCAs of electrochemical CO₂ mineralization studies, identify research gaps and discuss challenges, and suggest guidelines for applying the ISO 14040/14044 LCA methodology in this sector. Methods: This paper undertook a comprehensive review of LCA studies on CO₂ mineralization with emphasis on electrochemical mineralization. We utilized relevant keywords based on the theme to search in …

Poor Esg: Regressive Effects Of Climate Stewardship, Zohar Goshen, Assaf Hamdani, Alex Raskolnikov

Faculty Scholarship

The rise of inequality and global warming are the two ultimate challenges of our time. After decades of congressional failure to address climate change, the private sector has stepped in and adopted a set of environmental, social, and governance (ESG) policies as a market-based solution to a public policy failure. ESG advocates hope that corporate executives would save our planet. Where Congress failed, ESG will succeed.

This Article argues that if ESG-driven climate stewardship ever achieves the scale necessary to have a real impact on global warming, it will hurt the poor. Legislative interventions to combat climate change are nearly …

Mif-Cd74 Signaling Drives Immune Modulation In Medulloblastoma, Benjamin Draper, Zhen You, Dean Thompson, Xu Guo, Alaide Morcavallo, Diego Chillon Pino, Carlos Lorenzo Gido Nery, Sumana Shrestha, Chantelle E Bowers, Courtney Himsworth, Alberto Delaidelli, Bethany Remeniuk, Sonia Morlando, Brandon Wade, Freya Gordon, Yara Sanchez-Corrales, Bei Hopkins, Natalie Monteiro, Darren Locke, Miao Liu, Jacob Torrejon Diaz, Kevin Greenslade, Barbara Martins Da Costa, Karen Barker, Colin Kwok, Olumide Ogunbiyi, Anya Fletcher, Stacey Richardson, Carlos Custodia, Rafael Roque, Thomas Jackson, Regan Barfoot, Sergi Castellano, Rebecca M Hill, Olivier Saulnier, Thomas S Jacques, Michael D Taylor, Claudia C Faria, Olivier Ayrault, Poul H Sorensen, John Anderson, Louis Chesler, L Frank Huang, Steven C Clifford, Laura K Donovan

Faculty, Staff and Students Publications

Background: Relapsed medulloblastoma remains a significant therapeutic challenge as it is near universally fatal. The tumor microenvironment of medulloblastoma plays a critical role in tumor progression, influencing tumor growth, immune evasion, and therapeutic resistance. We hypothesized that defining tumor-immune interactions in diagnostic and relapsed medulloblastoma may uncover mechanisms of immune evasion and identify novel therapeutic targets.

Methods: We analyzed paired primary and recurrent RNA-sequencing data from 140 medulloblastoma patients to profile immune cell composition and validate spatial relationships within the TME. To identify key tumor-immune interactions, we developed a novel algorithm to detect receptor-ligand pairs using single-cell RNA-sequencing data. These …

Full Issue

The Bridge

No abstract provided.

Not Just Monetary: Arts And Humanities Scholars’ Perspectives On The Costs Of Open Access Publishing, Lindsey Skaggs, Rachel Scott, Colby Cilento

Faculty and Staff Publications – Milner Library

Bibliometric and survey-based studies have documented different open access (OA) publishing practices among scholars across academic disciplines. This article reports on interviews conducted with arts and humanities scholars from the United States and explores how OA intersects with their research and publication practices. Beyond the considerable financial costs of OA publishing, findings demonstrate that arts and humanities scholars contend with opportunity, reputational, equity, and time costs as they consider and engage with OA publishing. The authors discuss the implications of these costs for librarians who facilitate the dissemination, discovery, and preservation of arts and humanities scholarship.

In-Operando Imaging For Mechanistic Insights And Process Optimization In The Biofuel-Driven Combustion Synthesis Of Cement And Precursor Phases, Shubham Agrawal, Jeffrey J. Long, Aditya Kumar, Narayanan Neithalath

Materials Science and Engineering Faculty Research & Creative Works

Biofuel-based combustion synthesis (BCS) is a promising low-carbon pathway for decarbonizing cement production, providing an alternative to the fossil-fuel-driven clinkering process typically conducted at ∼1450 °C. Understanding microscale combustion mechanisms is essential to efficiently transfer biofuel-generated heat to cement precursors for targeted phase formation. Unlike previous studies focusing on macro-scale parameters such as fuel content/type, porosity, and holding temperature, this work provides mechanistic insights into microscale combustion behavior, linking microstructural phenomena with macro-scale processing conditions to guide parameter optimization. In-operando microscale imaging was employed to examine combustion wave propagation, spatio-temporal temperature evolution, and microstructural transformations within reactive pellets. Two combustion …

Strong And Ductile Additively Manufactured Ti-6al-4v Through Yttrium Inoculation, Saeid Alipour, Ji Young Kim, Min Seok Kim, Arezoo Emdadi, Ju Li

Materials Science and Engineering Faculty Research & Creative Works

The unique microstructural features and thermal cycles in alloys produced by additive manufacturing (AM) techniques have led to the emergence of a new paradigm in the design and development of alloys for performance-critical applications. Despite the inherent microstructural features of AMed parts, optimizing the porosity-microstructure while acquiring desired mechanical performance has been crucial yet challenging. Hence, in many legacy alloys, achieving a strength-ductility synergy in the as-built condition without applying post-heat treatment or hybrid processes is considered an arduous task. In this research, we aimed to tailor the microstructure of the legacy Ti-6Al-4V alloy in the as-built condition by implementing …

Evaluation Of Iron-Phosphate Glass–Ceramic Waste Form For Electrorefiner Salt Waste Simulant Dechlorinated With Phosphoric Acid, Harmony Werth, Paige Murray, Lucas Greiner, Jade Beland, Charmayne Lonergan, Brian Riley, Krista Carlson

Materials Science and Engineering Faculty Research & Creative Works

The importance of glass and glass–ceramic nuclear waste forms has been reaffirmed in recent years by the growing interest in nuclear power as a reliable energy source. Determination of processing methods for the disposal of halide-containing wastes will be essential for the advancement of nuclear technologies such as non-aqueous fuel reprocessing. Phosphate-based dechlorination and subsequent vitrification of radioactive salt waste into an iron-phosphate waste form have been identified as a potential processing scheme for electrochemical processing waste. The impact of H₃PO₄-based dechlorination of complex salt mixtures on the vitrification process and structure of the final iron-phosphate …

A Comparative Analysis Of Macro-Scale And Micro-Scale Pcswmm Models For Urban Flood Simulation In The Ormond Drainage System, Binit Gautam

LSU New Orleans Theses and Dissertations

This research utilized an existing SWMM modeling framework of the Ormond area within St. Charles Parish, Louisiana. A micro scale PCSWMM model was updated using GIS Derived values for CN, percent imperviousness, and subcatchment slope and compared to an macro-scale model. Models were compared under several storm events, which included the recent May 14, 2020 storm as well as 2-, 10-, and 100-year design storms. Peak flow, total inflow volume, and hydrograph characteristics were analyzed to assess response of each model.

The results show that the macro-scale model generally produces higher peak flows and total volumes, while the micro-scale model …

Machine Vision For In Situ Measurement And Control Of Wire Stickout In Lwded Process, Braden Mclain, Remy Mathenia, Todd Sparks, Frank Liou

Mechanical and Aerospace Engineering Faculty Research & Creative Works

This work presents a machine-vision–based measurement and control framework for laser wire directed energy deposition (LWDED) processes. A visible-light camera system is used to capture meltpool images, from which a novel vision algorithm extracts the wire–meltpool interface location. By utilizing a camera that is rigidly mounted to the deposition head, the vision algorithm provides a relative measurement of the distance between the nozzle tip and the workpiece, also referred to as wire stickout. A proportional-derivative (PD) control strategy is implemented using the measured stickout as feedback to adjust deposition feedrate. Results show that the control system successfully compensates for improper …

“It’S Hard To Look At All Our Trauma All At Once”: What Personal Narratives Reveal About The Triple Burden Of Intimate Partner Violence, Substance Use, And Homelessness, Céline E. Guedj

All Student Scholarship

Scope of the Problem

Intimate partner violence constitutes a pervasive public health issue, impacting nearly half of all women in the United States, about 61.7 million, over the course of their lifetime (Leemis et al., 2022). For Black, Latina, Indigenous and Asian Women, these rates are even higher. The majority of women of color will experience intimate partner violence, including nearly 2 out of 3 mutiracial women, demonstrating a grave overrepresentation amongst victims (Leemis et al., 2022). A study of college students found that LGBTQ women are even more likely to be targeted by abusive partners than their cis and …

The Mosaic, Georgia Southern University

George-Anne Media Group: Newsletters & Magazines

No abstract provided.

Most-Favored-Nation Benchmarking Versus Value-Based Contracting: Institutional Fit Of Pharmaceutical Pricing Tools In The United States, Canada, And The United Kingdom, Kola Adegoke, Olajide Alfred Durojaye, Abimbola Adegoke, Adeyinka Adegoke

Health & Biomedical Sciences Faculty Publications

Background: Soaring drug prices pose a significant obstacle to affordable and equitable access to medicines in high-income healthcare systems. This study compares two leading reform tool families, Most Favored Nation (MFN)/international reference pricing (IRP) and value-based contracting (VBC), across the United States, Canada, and the United Kingdom, with attention to cost containment, value-linked incentive design, equity of access, and implementation feasibility. U.S. policy developments (CMS Innovation Center’s GENEROUS, GLOBE, and GUARD models) extend international benchmark-based design options beyond the 2020 MFN rule.

Methods: Guided by institutional and governance theories, we conducted a structured comparative policy analysis using a four-dimensional trade-off …

From Mono To Object: A Contextual Evolution Of R&B And Soul Vocal Production Techniques With Emphasis On Object-Based Audio In Dolby Atmos, Samuel W. Slape

Electronic Theses and Dissertations

The human voice is the central element in much of recorded commercial music, and in R&B it serves as the primary vehicle of expression. Across the evolution of reproduction formats, including mono, stereo, surround, and Dolby Atmos, engineers have adapted strategies to preserve vocal clarity while exploring new spatial possibilities. This thesis examines how these shifts in technology and perception have shaped vocal production, using R&B as a lens for the relationship between format and artistic practice. Psychoacoustics provides a foundation for understanding how listeners perceive localization, masking, and vocal prominence. Analytical approaches are introduced to distinguish direct and indirect …

Bass And Drum Grooves In R&B: Analysis And Composition, Hugh Taylor

Electronic Theses and Dissertations

The term “R&B” has existed within the musical lexicon for nearly eighty years. It was first introduced in 1949 to replace the label “race music,” and was a combination of blues, jazz, gospel, and rock. Since then, the genre has transitioned from swing-based, live instrumentation toward straight-eighth backbeats and electronically produced sounds. Despite these shifts, contemporary R&B continues to borrow from its ancestral roots while maintaining a modern aesthetic. A primary feature that has persisted through this landscape is the “groove,” specifically defined here as the rhythmic layer created by the drums and bass. In R&B, the bass provides both …

Pedagogy Of Immersive Audio In Music For Collegiate Application, Nathaniel Q. Stansbury

Electronic Theses and Dissertations

Academia has always struggled to keep up with the fast-changing audio industry. Recent developments in immersive audio have further widened this gap, and comparatively few pedagogical materials exist to assist in addressing the problem. This manuscript proposes a three-course curriculum designed to prepare undergraduate engineers for immersive music production. Course I introduces the history and terminology of immersive audio. Course II explores DAW signal flow, production procedures, and major immersive formats. Course III focuses on applied mixing, giving students hands-on experience. The curriculum acts as an opportunity for universities and educators to better equip students going into the music industry. …

Integrated Geophysical, Geotechnical, And Mineralogical Characterization Of Expansive Weches Formation Soils In East Texas: Implications For Infrastructure Design, Samuel Annobil

Electronic Theses and Dissertations

This study investigates the geotechnical, geophysical, and mineralogical characteristics of soils derived from the Weches Formation in Nacogdoches County, East Texas, with emphasis on the relationships among electrical resistivity, moisture condition, compaction state, and mineralogical composition. The Weches Formation is well known for producing clay-rich, moisture-sensitive soils that pose challenges to subgrade performance because of their plasticity and swelling behavior. Representative soil samples were collected and subjected to laboratory testing, including particle size analysis, Atterberg limits, Standard Proctor compaction, free swell tests, electrical resistivity measurements, and X-ray diffraction (XRD) mineralogical analysis. The soils are predominantly fine-grained and clay-rich, with USCS …