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Manufacturing Processes Of A Wooden Tortilla Press: Idea To Production, Emma J. Palmer, Glenn Walker, Colleen Nolan, Olivia Marque, Benjamin Bird May 2026

Manufacturing Processes Of A Wooden Tortilla Press: Idea To Production, Emma J. Palmer, Glenn Walker, Colleen Nolan, Olivia Marque, Benjamin Bird

Honors Theses

This thesis follows the Manufacturing Process of a Wooden Tortilla Press from idea to production following lean manufacturing processes and producing a valuable, and profitable product.


Homeschool Policy In Mississippi: Perceptions Of Regulations Among Parents, Alumni, And Policy Advocates, Kaley Lecroy May 2026

Homeschool Policy In Mississippi: Perceptions Of Regulations Among Parents, Alumni, And Policy Advocates, Kaley Lecroy

Honors Theses

In recent years, the growth of homeschooling and alternative education methods such as hybrid and virtual schools has reshaped educational opportunities for both parents and students. As more options become available and more parents opt for the flexibility of non-traditional school, it is imperative that we examine the educational guardrails in place for these students. Even more importantly, it is imperative that the perspectives of home educators and homeschool alumni have a place at the table when we review the regulations in place. This thesis seeks to understand the perspectives of current and former Mississippi home educators, Mississippi homeschool alumni, …


Inflammatory Markers In The Emergency Department And Ptsd Symptoms In The Aurora Study: A Longitudinal Cohort Study, Kristen Nishimi, Sarah Linnstaedt, Thomas Neylan, Lauren Mckibben, Liz Marie Albertorio-Sáez, Ying Zhao, Stacey House, Francesca Beaudoin, Xinming An, Jennifer Stevens, Gari Clifford, Tanja Jovanovic, Laura Germine, Scott Rauch, John Haran, Alan Storrow, Paul Musey, Phyllis Hendry, Sophia Sheikh, Brittany Punches, Robert Swor, Jose Pascual, Mark Seamon, Elizabeth M Datner, Claire Pearson, David Peak, Roland Merchant, Robert Domeier, Niels Rathlev, Brian O'Neil, Paulina Sergot, Leon Sanchez, Steven Bruce, Steven Harte, Ronald Kessler, Karestan Koenen, Kerry Ressler, Samuel Mclean, Aoife O'Donovan May 2026

Inflammatory Markers In The Emergency Department And Ptsd Symptoms In The Aurora Study: A Longitudinal Cohort Study, Kristen Nishimi, Sarah Linnstaedt, Thomas Neylan, Lauren Mckibben, Liz Marie Albertorio-Sáez, Ying Zhao, Stacey House, Francesca Beaudoin, Xinming An, Jennifer Stevens, Gari Clifford, Tanja Jovanovic, Laura Germine, Scott Rauch, John Haran, Alan Storrow, Paul Musey, Phyllis Hendry, Sophia Sheikh, Brittany Punches, Robert Swor, Jose Pascual, Mark Seamon, Elizabeth M Datner, Claire Pearson, David Peak, Roland Merchant, Robert Domeier, Niels Rathlev, Brian O'Neil, Paulina Sergot, Leon Sanchez, Steven Bruce, Steven Harte, Ronald Kessler, Karestan Koenen, Kerry Ressler, Samuel Mclean, Aoife O'Donovan

Department of Emergency Medicine Faculty Papers

BACKGROUND: Systemic inflammation is hypothesized to contribute to post-traumatic stress disorder (PTSD) vulnerability. Few studies have examined inflammation shortly after trauma as a predictor of later PTSD symptoms. We examined whether inflammation from the emergency department (ED) post-trauma is associated with PTSD symptom severity over the following 6 months.

METHODS: Our sample included 742 AURORA participants, a longitudinal cohort of patients in 29 EDs across the United States after a traumatic stressor, followed up to 6 months. Plasma cytokines were assessed from a study blood draw in the ED: an inflammatory index (standardized sum of generally pro-inflammatory markers interleukin [IL]-6, …


Effects Of Increased Salinity On Mississippi Coast Bacterial Community Composition And Diversity, Clifton C. Wade May 2026

Effects Of Increased Salinity On Mississippi Coast Bacterial Community Composition And Diversity, Clifton C. Wade

Honors Theses

Bacterial communities are important to ecosystem function in coastal environments, but the response of these communities to short term increased salinity conditions is understudied. This study utilized a microcosm setup to investigate the response of coastal seawater bacterial communities to three treatments: an unamended seawater control, a reference treatment that received reverse osmosis (RO) water, and an elevated salinity treatment that received artificial seawater dissolved in RO water. Microcosms were sampled four times over a five-day period to analyze the effects of time under different salinity conditions on the seawater bacterial community. 16S rRNA gene sequencing was used to analyze …


Nutrilog: Design And Development Of A Full-Stack Web Application For Holistic Health Tracking, Jaromir J. Saloni May 2026

Nutrilog: Design And Development Of A Full-Stack Web Application For Holistic Health Tracking, Jaromir J. Saloni

Honors Theses

NutriLog is a web-based fitness and nutrition tracking application designed to help users record, organize, and interpret personal health data in one centralized platform. Many existing applications focus primarily on either nutrition tracking or exercise performance, which can make it difficult for users to understand how food intake and physical activity interact. NutriLog addresses this gap by combining food logging, exercise logging, calorie adjustment, nutrition summaries, and historical tracking into a single dashboard-based interface.

The application was developed using React and TypeScript for the frontend and Supabase for authentication, database storage, and user-specific data management. Nutrition data is supported through …


Modalities Of Vision Restoration In Optic Neuropathies And Retinal Disease, Batsheva Rubin, Fabio Lavinsky, Rachel Cain, Ajay E. Kuriyan, Gadi Wollstein, Ronald Zambrano, Joel Schuman May 2026

Modalities Of Vision Restoration In Optic Neuropathies And Retinal Disease, Batsheva Rubin, Fabio Lavinsky, Rachel Cain, Ajay E. Kuriyan, Gadi Wollstein, Ronald Zambrano, Joel Schuman

Wills Eye Hospital Papers

Visual impairment affects over 250 million people globally and carries a significant psychosocial and economic burden. In recent years, rapid advancements in biomedical engineering and regenerative medicine have driven the development of innovative therapies aimed at restoring visual function. Here, we first provide an overview of the visual pathway, imaging modalities, and the psychosocial and economic burden of vision loss. Then we review four vision restoration approaches: gene and stem cell therapies, optogenetics, retinal prosthetic devices, and visual pathway electrical stimulation. For each therapeutic approach, the mechanism of action, clinical outcomes, adverse events, and current limitations are discussed. Stem cell …


Service-Learning In Adapted Physical Activity: Student Experiences With And Without Course Integration, Courtney Jost, Nicole Fiscella Nicole Fiscella, Roxanne Bahn-Bales, Tze-Hsuan Wang, Jennifer Beamer, Jennifer Taylor, Willie Chun Wai Leung May 2026

Service-Learning In Adapted Physical Activity: Student Experiences With And Without Course Integration, Courtney Jost, Nicole Fiscella Nicole Fiscella, Roxanne Bahn-Bales, Tze-Hsuan Wang, Jennifer Beamer, Jennifer Taylor, Willie Chun Wai Leung

Educational Practices in Kinesiology

Service-learning is widely used in adapted physical activity/education (APA/APE) courses to enhance student learning through community engagement. However, limited research has explored how the presence or absence of an APA/APE course influences students’ perceived learning, confidence, and engagement in inclusive physical activity settings. This quasi-experimental, cross-sectional study examined how course-enhanced and purely experiential models of a university-based APA service-learning program, PA PALS, shaped undergraduate students’ experiences. Students (N = 58) participated; 41.4% (n = 24) were concurrently enrolled in an APA/APE course (course-enhanced group), while 58.6% (n = 34) participated as volunteers (purely experiential group). A validated …


Ballistics Characterization Of Micro-Truss Reinforced Lunar-Inspired Geopolymer Concrete For Space Construction, Phoebe G. Johnson May 2026

Ballistics Characterization Of Micro-Truss Reinforced Lunar-Inspired Geopolymer Concrete For Space Construction, Phoebe G. Johnson

Honors Theses

This research investigates the ballistics response and compressive strength of a Fly Ash/ Lunar Regolith hybrid geopolymer concrete developed for space construction. The study aimed firstly to optimize the Fly Ash/ Regolith mix ratio for maximum mechanical performance and secondly, to evaluate the effectiveness of carbon-fiber micro-truss reinforcement, produced by 3D printing, in mitigating damage from high-velocity impacts. Concrete specimens with varying Fly Ash-to-Regolith ratios (100-50% Fly Ash) were fabricated and tested under compression and ballistic loading. Compressive strength tests followed ASTM C109 using a 110 Kip 810-MTS testing apparatus on both unreinforced and reinforced 2” cubes. For unreinforced samples, …


Development Of A Putting Green Manufacturing Process, Jose Andres Cepeda Santiago May 2026

Development Of A Putting Green Manufacturing Process, Jose Andres Cepeda Santiago

Honors Theses

Our Capstone project investigates the end-to-end design, development, and production of a 6‑foot long portable putting green marketed for individuals seeking a high quality, competitively priced golf product for home or office use. The capstone project examines the full lifecycle of product creation applying manufacturing principles learned through the center of manufacturing’s coursework. From the initial concept through engineering design, market research, prototyping, manufacturing optimization, and final production the project emphasizes cross‑functional collaboration across engineering, business, and accountancy majors. Methods used to gather data included marketing surveys, CAD drawings, time studies during production runs, value stream mapping, and controlled documentation …


Development Of A Putting Green Manufacturing Process, Avalon R. Madden May 2026

Development Of A Putting Green Manufacturing Process, Avalon R. Madden

Honors Theses

Our Capstone project investigates the end to end design, development, and production of a 6‑foot long portable putting green marketed for individuals seeking a high quality, competitively priced golf product for home or office use. The capstone project examines the full lifecycle of product creation applying manufacturing principles learned through the center of manufacturing’s coursework. From the initial concept through engineering design, market research, prototyping, manufacturing optimization, and final production the project emphasizes cross‑functional collaboration across engineering, business, and accountancy majors. Methods used to gather data included marketing surveys, CAD drawings, time studies during production runs, value stream mapping, and …


The Design And Manufacturing Process Of The Concealed Shelf, Emma R. Freeman May 2026

The Design And Manufacturing Process Of The Concealed Shelf, Emma R. Freeman

Honors Theses

The Haley Barbour Center for Manufacturing Excellence (CME) at the University of Mississippi challenges students to manufacture a product and put forth a balanced manufacturing line in a senior capstone project. The chosen product was a concealed shelf, or a shelf with a hidden compartment. The team aimed to design a product, formulate a project plan, analyze the market, conduct financial analysis, develop a prototype, establish a manufacturing process, and demonstrate that process in two production runs. The team used tools such as Computer Aided Design (CAD), market surveys, jig creation, and line balancing to accomplish these tasks. After two …


Synthesis Of A Halogenated Glyoxime For Cobalt Deposition Suppression, Liam S. Allen May 2026

Synthesis Of A Halogenated Glyoxime For Cobalt Deposition Suppression, Liam S. Allen

Honors Theses

Dr. Qiang Huang at the University of Alabama is a chemical engineering professor and works on the electrodeposition of metals to create circuitry. During this process suppressive molecules may be added to control help the process. This project focuses on synthesizing an alpha-halogenated glyoxime to test whether the compound is a more effective suppressant in comparison to regular glyoximes. More specifically the target chemical is called bromo-dimethylglyoxime which is created in a two-stage reaction. The starting material, diacetyl monoxime, is brominated at the alpha carbon position. The product of this reaction, officially called bromodimethylglyoxalmonoxime, is then reacted with hydroxylammonium chloride …


The Optimization Of A Robotic Welding Arm To Improve Efficiency, Margaret Close May 2026

The Optimization Of A Robotic Welding Arm To Improve Efficiency, Margaret Close

Honors Theses

The main objective of this report is to optimize a robotic welding arm to improve a locker manufacturing process. The robotic welding arm, a Miller PerformArc, used by Lockers Manufacturing has been producing spatter. Spatter significantly reduces the quality of the product and increases the product’s manufacturing time. The goal of this project was to find the best solution to reduce spatter without weakening the welds and ensuring that efficiency will increase. The first step in this project was to test multiple weld testing variables such as voltage, current, welding angle, robot speed, and arc and crater ratios. For each …


Studying More, Not Less: Rethinking Test Anxiety In Undergraduate Biology Courses, Kailey E. Reeves May 2026

Studying More, Not Less: Rethinking Test Anxiety In Undergraduate Biology Courses, Kailey E. Reeves

Honors Theses

This study investigates the relationships among test anxiety, study behaviors, and metacognitive evaluation in undergraduate biology courses. While prior research has established that study strategies and metacognition influence academic performance, less is known about how these factors interact with test anxiety in undergraduate Biology courses. Guided by the student approaches to learning (SAL) and metacognition frameworks, this study examines whether test anxiety is associated with the type and number of study strategies students use, as well as their ability to evaluate their own learning and preparedness. Using a convergent parallel mixed-methods design, data was collected from 205 students enrolled in …


Hyposense: Multimodal Physiologic And Voc Wearable For Early Hypoglycemia Detection, Nidhi R. Patel May 2026

Hyposense: Multimodal Physiologic And Voc Wearable For Early Hypoglycemia Detection, Nidhi R. Patel

Honors Theses

Hypoglycemia remains a significant safety concern for insulin-dependent individuals, especially when blood glucose declines rapidly during exercise, sleep, or periods of impaired hypoglycemia awareness. Current continuous glucose monitors and automated insulin delivery systems have helped to improve diabetes management, but these technologies primarily respond to glucose trends after they have already started and may not actually provide sufficient warning before symptoms occur. This thesis describes the development of HypoSense, a noninvasive wrist worn wearable concept that is designed to support earlier hypoglycemia risk detection through multimodal physiologic and volatile organic compound emission sensing. HypoSense combines volatile organic compounds/gas sensing with …


What Do We Owe A Drowning Coast? Examining Louisiana's Coastal Crisis Through The Lens Of Environmental Justice, Owen M. Plaisance May 2026

What Do We Owe A Drowning Coast? Examining Louisiana's Coastal Crisis Through The Lens Of Environmental Justice, Owen M. Plaisance

Honors Theses

This thesis argues that human contributions to Louisiana’s coastal land loss constitute a form of environmental injustice that cannot be adequately addressed through frameworks focused solely on aggregate welfare or distributive fairness. While utilitarian and Rawlsian approaches offer important insights, both are limited in capturing the full scope of harm caused by environmental degradation. In coastal Louisiana, land loss undermines not only economic resources and physical security but also the substantive freedoms required for individuals and communities to live meaningful and culturally rooted lives, while disrupting ecological systems and non-human flourishing. To address these limitations, the thesis develops the Capabilities …


Just War Theory And Coercive Non-Proliferation: Ethically Evaluating Nuclear Prevention Efforts, P. Walker Jacklin May 2026

Just War Theory And Coercive Non-Proliferation: Ethically Evaluating Nuclear Prevention Efforts, P. Walker Jacklin

Honors Theses

This thesis examines the ethics of coercively addressing non-nuclear states who are attempting to acquire nuclear weapons. Nuclear weapons pose a serious danger on a global scale, so ethical analysis should balance these consequences with the coerciveness of state intervention. Just War Theory provides a useful framework that balances these considerations.  Using the criteria of Just War Theory, this thesis examines two 21st century non-proliferation operations: Operation Orchard and Operation Midnight Hammer. I find that Operation Orchard fails the criteria of Just War Theory, while Operation Midnight Hammer satisfies the criteria. Making this determination is ethically risky, however, because our …


Understanding Stakeholders’ Perceptions Of Liberia’S Accelerated Learning Program: A Generic Qualitative Study, Aagon Fremling Tingba, Jr. May 2026

Understanding Stakeholders’ Perceptions Of Liberia’S Accelerated Learning Program: A Generic Qualitative Study, Aagon Fremling Tingba, Jr.

Walden Dissertations and Doctoral Studies

No abstract provided.


The Design And Manufacturing Process Of The Concealed Shelf, Mexrojiddinbek Sattorov May 2026

The Design And Manufacturing Process Of The Concealed Shelf, Mexrojiddinbek Sattorov

Honors Theses

This document contains information regarding the design and build process of the Concealed Shelf, which is a furniture product with hidden storage capability. First, the team members decided on the design of the product, followed by market analysis and manufacturing feasibility. Lean manufacturing principles were applied to improve the process efficiency and reduce waste.

Multiple prototypes were built with varying raw materials and locking mechanisms. Jigs and fixtures were handcrafted to ensure more consistent product quality. Two production runs were conducted to evaluate performance and identify areas for improvement.

The final design includes economic considerations, manufacturing layout, and continuous improvement …


Thermal Management Of Electric Vehicle Batteries Using Multi-Directional Immersion Cooling Techniques, Lindsey T. Mcgee May 2026

Thermal Management Of Electric Vehicle Batteries Using Multi-Directional Immersion Cooling Techniques, Lindsey T. Mcgee

Honors Theses

Through the years, liquid cooling has been the most prominent technique used to regulate the temperature in electric vehicle (EV) batteries. This involves a circulating coolant running through a closed-loop system that passes through each of the channels within the lithium-ion battery. While effective, this design has certain limitations. Since the coolant is not making direct contact with the battery cells, its’ capabilities to cool are greatly hindered. Immersion cooling techniques have shown to be an effective cooling method for lithium-ion batteries. This method involved running a dielectric fluid flow across the body of the battery cells. With the immersion …


Optimization And Safety Protocols For An Acetone Production Plant, Holley J. Garrison May 2026

Optimization And Safety Protocols For An Acetone Production Plant, Holley J. Garrison

Honors Theses

The proposed acetone production plant, scheduled for start-up in 2028, is capable of producing 3,750 kg/h of 99.9 wt% acetone. Using an endothermic catalytic dehydrogenation reaction, a feed of isopropyl alcohol (IPA) is reacted to produce 30,000 metric tons per year (MT/y) of acetone. Initial design and economic analysis of this process found that this plant will not be economically viable due to its Net Present Value (NPV) of -$132M. Optimization efforts prioritized reductions in raw materials and improved product recovery. Several optimizations were performed to reduce the feed rate, including switching to the low temperature catalyst, shortening the reactor …


Plastic Material Analysis And Bonding In Small Aquatic Vessels, Andrew R. Orr May 2026

Plastic Material Analysis And Bonding In Small Aquatic Vessels, Andrew R. Orr

Honors College Theses

This project presents the design and development of a suitable vessel for small-scale aquatic applications. The developed project is used for a remote-controlled duck hunting system, and the parameters of the design are based on the requirements for the system as a whole. Traditionally, plastics are fabricated using blow molding to create a single seamless form. However, for small-scale prototyping with limited resources, this method of fabrication is unsustainable for short-term, non-industrial design applications. As a result, an existing longer hull is selected and shortened to meet the required project length. The project evaluates multiple initial hull designs, ultimately selecting …


Re: Comment Letter For Old Butte Silver Bow Landfill/Clark Tailings Consolidated Waste Management Area (Ctcwma) Remedy Effectiveness Evaluation Phase I (Conceptual Site Model) (Dated February 27, 2026), Emma Rott May 2026

Re: Comment Letter For Old Butte Silver Bow Landfill/Clark Tailings Consolidated Waste Management Area (Ctcwma) Remedy Effectiveness Evaluation Phase I (Conceptual Site Model) (Dated February 27, 2026), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Correction: Case, R.P.; Hupy, J.P. Methods For Gis-Driven Airspace Management: Integrating Unmanned Aircraft Systems (Uass), Advanced Air Mobility (Aam), And Crewed Aircraft In The Nas. Drones 2026, 10, 82, Ryan P. Case, Joseph P. Hupy May 2026

Correction: Case, R.P.; Hupy, J.P. Methods For Gis-Driven Airspace Management: Integrating Unmanned Aircraft Systems (Uass), Advanced Air Mobility (Aam), And Crewed Aircraft In The Nas. Drones 2026, 10, 82, Ryan P. Case, Joseph P. Hupy

Aviation Technology Graduate Student Publications

A correction has been made to Section 2. Materials and Methods, paragraph 4.

In 2023, a Purdue University DJI M300 was conducting an RGB (Red, Green, Blue) mapping mission near the Purdue water tower on the Northwest side of campus. Just after 5:00 PM Eastern, the DJI M300 UAS operator was alerted of an aircraft entering their mapping mission airspace and took action to increase separation until the threat had passed. The DJI M300 UAS team had appropriate LAANC approval and waivers in place to conduct their mission and had a VHF radio monitoring KLAF Tower communications. The DJI M300 …


Social Prescribing For Refugee Populations: A Rapid Realist Review Of International Evidence, Victoria Touzel, Doreen Reifegerste, Luisa Bartz, Anna-Lena Esser, Kerryn Husk May 2026

Social Prescribing For Refugee Populations: A Rapid Realist Review Of International Evidence, Victoria Touzel, Doreen Reifegerste, Luisa Bartz, Anna-Lena Esser, Kerryn Husk

Peninsula Medical School

BackgroundSocial prescribing offers potential for addressing social determinants of health and supporting health equity among disadvantaged groups. However, evidence for refugee populations remains limited, despite this group facing profound social and systemic barriers. This rapid realist review synthesizes social prescribing and comparable social-capital based intervention evidence to address this gap.MethodsWe conducted a RAMESES-compliant rapid realist review supported by an expert advisory board. Searches across six databases (2014–2024) were supplemented by grey literature and citation chasing strategies. Eligible studies included refugee, asylum-seekers and forcibly displaced populations engaged in either formal social prescribing or comparably operationalized social-capital interventions. Synthesis developed Context-Mechanism-Outcome configurations …


Re: Conditional Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Clark Tailings Consolidated Waste Management Area (Ctcwma) Site Investigation Quality Assurance Project Plan (Qapp) (Dated April 16, 2026), Emma Rott May 2026

Re: Conditional Approval Letter For The Butte Priority Soils Operable Unit (Bpsou) Clark Tailings Consolidated Waste Management Area (Ctcwma) Site Investigation Quality Assurance Project Plan (Qapp) (Dated April 16, 2026), Emma Rott

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.


Elementary Public School Principals’ Decision Process For Hiring Teachers In The U.S. Mid-Atlantic Region, Charmaine Gray May 2026

Elementary Public School Principals’ Decision Process For Hiring Teachers In The U.S. Mid-Atlantic Region, Charmaine Gray

Walden Dissertations and Doctoral Studies

No abstract provided.


Relationship Between Transformational Leadership And Perceived Job Satisfaction Among Information Technology Employees, Arik Snyder May 2026

Relationship Between Transformational Leadership And Perceived Job Satisfaction Among Information Technology Employees, Arik Snyder

Walden Dissertations and Doctoral Studies

No abstract provided.


Linkedin Growth & Engagement Analysis, Dora Nguyen May 2026

Linkedin Growth & Engagement Analysis, Dora Nguyen

Paul English Applied Artificial Intelligence (AI) Institute Publications

This report presents a data analysis of the LinkedIn marketing efforts of the Paul English Applied Artificial Intelligence Institute (PEAAII) at the University of Massachusetts Boston. The analysis examines follower growth trends, audience demographics, engagement patterns, and content performance between February and April 2026. Findings highlight significant organic growth driven primarily by AI Workshop Series and event-related content, along with increased visibility through reposts and audience engagement. The report also identifies opportunities to expand reach through consistent posting, collaborations, interactive AI content, and broader community engagement initiatives. Recommendations are provided to support continued audience growth and strengthen the Institute’s digital …


Prevalence Of Adverse Events Following T-Cell Redirecting Therapies In Patients With Metastatic Castration-Resistant Prostate Cancer: A Pooled Analysis, Abhiraj Saxena, Marc Yorker, Nicholas Zorko, Vivek Narayan, Bilal Siddiqui, Biren Saraiya, William Tester, Patrick Mille, Amy Shaver, Nikita Nikita, Grace Lu-Yao, W. Kevin Kelly, Kevin K. Zarrabi May 2026

Prevalence Of Adverse Events Following T-Cell Redirecting Therapies In Patients With Metastatic Castration-Resistant Prostate Cancer: A Pooled Analysis, Abhiraj Saxena, Marc Yorker, Nicholas Zorko, Vivek Narayan, Bilal Siddiqui, Biren Saraiya, William Tester, Patrick Mille, Amy Shaver, Nikita Nikita, Grace Lu-Yao, W. Kevin Kelly, Kevin K. Zarrabi

Department of Medical Oncology Faculty Papers

BACKGROUND: T-cell redirecting therapies, including T-cell engagers (TCEs) and Chimeric Antigen Receptor T-cell (CAR-T), are under investigation in metastatic castration-resistant prostate cancer (mCRPC). Despite their promising therapeutic potential, these therapies remain in early stages of development due to treatment-related adverse events (TRAEs). This study aims to quantify the frequency and severity of adverse events in clinical trials with a pooled analysis.

MATERIALS AND METHODS: A systematic search of PubMed, CINHAL, Scopus, and Ovid was conducted to identify clinical trials evaluating TCEs or CAR-T in patients with mCRPC. Types and frequencies of TRAEs were collected and analyzed using a random-effects model. …