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Live-Work Interior Quality For Older People In Low-Income Housing In Bangkok, Sutida Sattayakorn, Soranart Sinuraibhan, Saithiwa Ramasoot, Supreeya Wungpatcharapon, Karim Hadjri, Isaiah Durosaiye, Junji Huang Jul 2023

Live-Work Interior Quality For Older People In Low-Income Housing In Bangkok, Sutida Sattayakorn, Soranart Sinuraibhan, Saithiwa Ramasoot, Supreeya Wungpatcharapon, Karim Hadjri, Isaiah Durosaiye, Junji Huang

Interiority

This study explores to determine the live-work housing needs of low-income older people in informal settlements, the ways of life of whom contemporary housing provision often fails to consider. A questionnaire survey was conducted in three communities in Klong Toey, the largest informal settlement in Bangkok, to understand households’ satisfaction levels and expectations regarding the interior quality of their live-work housing. Older people’s specific interior spaces and housing requirements and expectations vary depending on the nature of their livelihood activities that can be categorised into three main groups, namely service, cook, and stock. The findings suggest a strong relationship between …

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Butte Priority Soils Operable Unit (Bpsou) Draft Final Insufficiently Reclaimed Sites – Field Sampling Plan (Fsp) Bres No. 134 – Star West Dump, Mike Mcanulty Jul 2023

Butte Priority Soils Operable Unit (Bpsou) Draft Final Insufficiently Reclaimed Sites – Field Sampling Plan (Fsp) Bres No. 134 – Star West Dump, Mike Mcanulty

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

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Draft Final 2023 Residential Metals Abatement Program (Rmap) School Soil Sampling Field Sampling Plan (Fsp) Submittal #11 [Montana Technological University (North Campus)], Pioneer Technical Services, Inc. Jul 2023

Draft Final 2023 Residential Metals Abatement Program (Rmap) School Soil Sampling Field Sampling Plan (Fsp) Submittal #11 [Montana Technological University (North Campus)], Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

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Communion Anthropoid, Joshua Stanek Jul 2023

Communion Anthropoid, Joshua Stanek

Dissertations and Theses

In National Lampoon's Vegas Vacation, a man of good will offers all he has to a dear brother-in-law--recognizing the snakes he keeps as toys, the camper, the stones, dirt, and arid shrubbery are likewise dear to him. They go out to the desert at night and dig shallow holes, seemingly at random. Their imprecision is surprisingly fruitful. Imagine the constellation they made for the stars. In Communion Anthropoid, I am digging shallow holes in the dark with a mind to unearth what I believe I have lost. The dearness, I suppose. These poems vary in form from eight …

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Feminizing Decentralized Renewable Energy Programs: A Study Of A Community Renewable Energy Project From India, Aritra Chakrabarty Jul 2023

Feminizing Decentralized Renewable Energy Programs: A Study Of A Community Renewable Energy Project From India, Aritra Chakrabarty

Michigan Tech Publications

The increasing impact of global forces on local communities in the 21st century has necessitated a shift in focus from macro narratives to the micro-politics of planning. One of the critical areas of such micro-politics is energy policy-making in the Global South. It is argued that a bottom-up approach to energy intervention would increase the control and access of the end consumer to the sites of production, shift away from colonial energy production systems, and create more avenues for equitable community development. Within this context, this study critically evaluates a community-based renewable energy project from a feminist perspective. The study …

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The Transformation Of Congressional Policy Making In A Partisan Era, Patrick Rickert Jul 2023

The Transformation Of Congressional Policy Making In A Partisan Era, Patrick Rickert

Arts & Sciences Graduate Student Theses and Dissertations

This dissertation explores the transformation of Congressional politics away from traditional practices and the consequences of those changes. In the House of Representatives, I consider this with respect to the party and chamber rule changes introduced by the new Republican majority after the 1994 election, while in the Senate I use the lens of paired voting to evaluate how the Senate has evolved. The first chapter discusses the literature on party government and theorizes how parties have used committees to achieve their goals. Chapters 2 and 3 center how Speaker Newt Gingrich used rule changes to alter the relationship between …

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Agrp Neurons Are Not Indispensable For Body Weight Maintenance In Adult Mice, Jing Cai, Jing Chen, Joshua Ortiz-Guzman, Jessica Huang, Benjamin R Arenkiel, Yan Zhang, Qingchun Tong, Cheng Zhan Jul 2023

Agrp Neurons Are Not Indispensable For Body Weight Maintenance In Adult Mice, Jing Cai, Jing Chen, Joshua Ortiz-Guzman, Jessica Huang, Benjamin R Arenkiel, Yan Zhang, Qingchun Tong, Cheng Zhan

Faculty, Staff and Student Publications

In addition to their role in promoting feeding and obesity development, hypothalamic arcuate agouti-related protein/neuropeptide Y (AgRP/NPY) neurons are widely perceived to be indispensable for maintaining normal feeding and body weight in adults, and consistently, acute inhibition of AgRP neurons is known to reduce short-term food intake. Here, we adopted complementary methods to achieve nearly complete ablation of arcuate AgRP/NPY neurons in adult mice and report that lesioning arcuate AgRP/NPY neurons in adult mice causes no apparent alterations in ad libitum feeding or body weight. Consistent with previous studies, loss of AgRP/NPY neurons blunts fasting refeeding. Thus, our studies show …

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Deep Learning-Based Tem Image Analysis For Fully Automated Detection Of Gold Nanoparticles Internalized Within Tumor Cell, Amrit Kaphle, Sandun Jayarathna, Hem Moktan, Maureen Aliru, Subhiksha Raghuram, Sang Hyun Cho Jul 2023

Deep Learning-Based Tem Image Analysis For Fully Automated Detection Of Gold Nanoparticles Internalized Within Tumor Cell, Amrit Kaphle, Sandun Jayarathna, Hem Moktan, Maureen Aliru, Subhiksha Raghuram, Sang Hyun Cho

Faculty, Staff and Student Publications

Transmission electron microscopy (TEM) imaging can be used for detection/localization of gold nanoparticles (GNPs) within tumor cells. However, quantitative analysis of GNP-containing cellular TEM images typically relies on conventional/thresholding-based methods, which are manual, time-consuming, and prone to human errors. In this study, therefore, deep learning (DL)-based methods were developed for fully automated detection of GNPs from cellular TEM images. Several models of "you only look once (YOLO)" v5 were implemented, with a few adjustments to enhance the model's performance by applying the transfer learning approach, adjusting the size of the input image, and choosing the best optimization algorithm. Seventy-eight original …

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The Mastery Lifestyle Intervention To Reduce Biopsychosocial Risks For Pregnant Latinas And African Americans And Their Infants: Protocol For A Randomized Controlled Trial, Asim C Akbulut, Armand M Jaminon, Ehsan Natour, Roberto Lorusso, Joachim E Wildberger, Barend Mees, Geert Willem Schurink, Michael J Jacobs, Jack Cleutjens, Ingrid Krapels, Alexander Gombert, Jos G Maessen, Ryan Accord, Tammo Delhaas, Simon Schalla, Leon J Schurgers, Elham Bidar Jul 2023

The Mastery Lifestyle Intervention To Reduce Biopsychosocial Risks For Pregnant Latinas And African Americans And Their Infants: Protocol For A Randomized Controlled Trial, Asim C Akbulut, Armand M Jaminon, Ehsan Natour, Roberto Lorusso, Joachim E Wildberger, Barend Mees, Geert Willem Schurink, Michael J Jacobs, Jack Cleutjens, Ingrid Krapels, Alexander Gombert, Jos G Maessen, Ryan Accord, Tammo Delhaas, Simon Schalla, Leon J Schurgers, Elham Bidar

Faculty, Staff and Student Publications

Current management guidelines for ascending thoracic aortic aneurysms (aTAA) recommend intervention once ascending or sinus diameter reaches 5-5.5 cm or shows a growth rate of >0.5 cm/year estimated from echo/CT/MRI. However, many aTAA dissections (aTAAD) occur in vessels with diameters below the surgical intervention threshold ofMoreover, during aTAA repair surgeons observe and experience considerable variations in tissue strength, thickness, and stiffness that appear not fully explained by patient risk factors. To improve the understanding of aTAA pathophysiology, we established a multi-disciplinary research infrastructure: The Maastricht acquisition platform for studying mechanisms of tissue-cell crosstalk (MAPEX). The explicit scientific focus of the …

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Flux-Quanta Injection For Nonreciprocal Current Control In A Two-Dimensional Noncentrosymmetric Superconducting Structure, Serafim Teknowijoyo, Sara Chahid, Armen Gulian Jul 2023

Flux-Quanta Injection For Nonreciprocal Current Control In A Two-Dimensional Noncentrosymmetric Superconducting Structure, Serafim Teknowijoyo, Sara Chahid, Armen Gulian

Mathematics, Physics, and Computer Science Faculty Articles and Research

We designed and experimentally demonstrated a four-terminal superconducting device, a “quadristor,” that can function as a nonlatching (reversible) superconducting switch from the diode regime to the resistive state by application of a control current much smaller than the main transport current. The device uses a vortex-based superconducting-diode mechanism that is switched back and forth via the injection of flux quanta through auxiliary current leads. Our finding opens a new research area in the field of superconducting electronics.

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The Influence Of Mixing Duct Length And Phase Of Flight On Wall Temperatures Of A Rocket Based Combined Cycle Engine In Ejector And Air-Augmented Modes, Jonathan Grow Jul 2023

The Influence Of Mixing Duct Length And Phase Of Flight On Wall Temperatures Of A Rocket Based Combined Cycle Engine In Ejector And Air-Augmented Modes, Jonathan Grow

Doctoral Dissertations and Master's Theses

Rocket Based Combined Cycle (RBCC) engines have been theorized as a possible means of powering launch vehicles and high-speed atmospheric vehicles. By incorporating aspects of both air-breathing and rocket propulsion, RBCC engines promise up to a 230 % increase in specific impulse over traditional chemical rocket propulsion by entraining a secondary flow of atmospheric air and mixing it with the exhaust of a rocket motor. Students within the Embry-Riddle Future Space Explorers and Developers Society (ERFSEDS) identified a
problem of excessive heating and structural failure of the mixing duct during launch and transonic flight of a student-built flight test vehicle. …

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Membrane Stretch As The Mechanism Of Activation Of Piezo1 Ion Channels In Chondrocytes, Alireza Savadipour, Robert J Nims, Neda Rashidi, Jaquelin M Garcia-Castorena, Ruhang Tang, Gabrielle K Marushack, Sara J Oswald, Wolfgang B Liedtke, Farshid Guilak Jul 2023

Membrane Stretch As The Mechanism Of Activation Of Piezo1 Ion Channels In Chondrocytes, Alireza Savadipour, Robert J Nims, Neda Rashidi, Jaquelin M Garcia-Castorena, Ruhang Tang, Gabrielle K Marushack, Sara J Oswald, Wolfgang B Liedtke, Farshid Guilak

2020-Current year OA Pubs

Osteoarthritis is a chronic disease that can be initiated by altered joint loading or injury of the cartilage. The mechanically sensitive PIEZO ion channels have been shown to transduce injurious levels of biomechanical strain in articular chondrocytes and mediate cell death. However, the mechanisms of channel gating in response to high cellular deformation and the strain thresholds for activating PIEZO channels remain unclear. We coupled studies of single-cell compression using atomic force microscopy (AFM) with finite element modeling (FEM) to identify the biophysical mechanisms of PIEZO-mediated calcium (Ca

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Insight Into The Optimization Of Implementation Time In Cob Construction: Field Test And Compressive Strength Versus Drying Kinetics, K Touati, Sahmarany B Al, Guern M Le, Mendili Y El, F Streiff, S Goodhew Jul 2023

Insight Into The Optimization Of Implementation Time In Cob Construction: Field Test And Compressive Strength Versus Drying Kinetics, K Touati, Sahmarany B Al, Guern M Le, Mendili Y El, F Streiff, S Goodhew

School of Art, Design and Architecture

Mastering construction times is of paramount importance in making vernacular earth construction techniques attractive to modern clients. The work presented here is a contribution towards the optimization of the construction time of cob buildings. Therefore, this paper follows the evolution of a cob’s mechanical properties during its drying process in the case of a double-walling CobBauge system. Laboratory tests and in situ measurements were performed, and further results were described. Volumetric water content sensors were immersed in the walls of a CobBauge prototype building during its construction. The evolution of the cob layer’s compressive strength and Clegg Impact Value (CIV) …

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The Future Of Crypto-Asset Mining: The Inflation Reduction Act And The Need For Uniform Federal Regulation, Liz Guinan Jul 2023

The Future Of Crypto-Asset Mining: The Inflation Reduction Act And The Need For Uniform Federal Regulation, Liz Guinan

Sustainable Development Law & Policy

Crypto-asset mining is energy-intensive and environmentally harmful, presenting challenges and opportunities for federal, state and local governments, regulators, and society as a whole. As of December 2021, the United States has thirty-eight percent of the global crypto network hash rate, which is the total amount of computational power used to mine and process crypto transactions, making the United States the world’s largest crypto-asset mining industry. The total electricity consumption of crypto-asset mining in the United States is estimated to be around 121.36 terawatt-hours (“TWh”) per year, which is equivalent to the electricity consumption of approximately 10.9 million households in the …

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Test-Retest Reliability Of A 4-Minute All-Out Critical Force Test In Rock Climbers, Zachary J. Mcclean, Keenan Macdougall, Jared R. Fletcher, Saied J. Aboodarda, Brian R. Macintosh Jul 2023

Test-Retest Reliability Of A 4-Minute All-Out Critical Force Test In Rock Climbers, Zachary J. Mcclean, Keenan Macdougall, Jared R. Fletcher, Saied J. Aboodarda, Brian R. Macintosh

International Journal of Exercise Science

International Journal of Exercise Science 16(4): 912-923, 2023. The purpose of this study was to assess the test-retest reliability of a 4-minute all-out critical force test in well-trained rock climbers. Thirteen rock climbers (n=4 females) completed a familiarization session and two all-out critical force tests on different days. During each trial, participants completed 24 repetitions of 7s right-handed, maximal effort hangs from a 20mm edge interspersed with 3 s rest. The end-test force (EF; i.e., critical force), impulse above EF (IEF), and peak force achieved durin g the test were analyzed with paired t-tests to determine differences between trials. Intraclass …

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Bring On The Heat, Renée Stoute Jul 2023

Bring On The Heat, Renée Stoute

The Journal of International Relations, Peace Studies, and Development

According to the World Economic Forum, in retaliation to European Union sanctions and embargoes, Russia cut EU gas flows by around 80% between May and October 2022 (WEF, 2022). The EU, in turn, has had to not only reduce energy consumption within the public and private sectors but has also scrambled to find energy alternatives to compensate for its energy shortcomings. However, due to the EU’s rejection of Russian oil and gas, there are now opportunities to embrace more sustainable energy alternatives quicker than previously expected. This could lead to a faster transition towards the use of cleaner and more …

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Universal Design For Learning (Udl) In Inclusive Preschool Science Classrooms, Marla J. Lohmann, Katrina A. Hovey, Ariane N. Gauvreau Jul 2023

Universal Design For Learning (Udl) In Inclusive Preschool Science Classrooms, Marla J. Lohmann, Katrina A. Hovey, Ariane N. Gauvreau

Journal of Science Education for Students with Disabilities

Science instruction is a critical aspect of early learning. Teachers can support young children’s learning about scientific concepts through the use of the Universal Design for Learning (UDL) framework, which is a proactive approach to instructional planning that helps ensure success for all learners. This teaching techniques article offers preschool teachers practical solutions for implementing in the UDL framework for science instruction in their classrooms.

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From Rivals To Partners: The Evolution Of Environmental Cooperation Among China, Japan, And Korea, Changrui Yuan, Brice Tseen Fu Lee Jul 2023

From Rivals To Partners: The Evolution Of Environmental Cooperation Among China, Japan, And Korea, Changrui Yuan, Brice Tseen Fu Lee

Global: Jurnal Politik Internasional

This study analyses the trilateral cooperation among China, Japan, and Korea in the realm of environmental issues, focusing on the Trilateral Environment Ministers Meeting (TEMM) as the representative institution. Through a theoretical perspective based on rational design theory, this paper examines the rationality of TEMM's design and how it has addressed the enforcement problems and asymmetry of control among the three countries. The study also suggests some strategies for further deepening and empowering the trilateral cooperation, such as developing the environmental protection industry and carbon trading market, involving funds and non-state actors, and improving institutionalization. While acknowledging the achievements and …

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Understanding Political Polarization Using Language Models: A Dataset And Method, Samiran Gode, Supreeth Bare, Bhiksha Raj, Hyungon Yoo Jul 2023

Understanding Political Polarization Using Language Models: A Dataset And Method, Samiran Gode, Supreeth Bare, Bhiksha Raj, Hyungon Yoo

Natural Language Processing Faculty Publications

Our paper aims to analyze political polarization in US political system using language models, and thereby help candidates make an informed decision. The availability of this information will help voters understand their candidates' views on the economy, healthcare, education, and other social issues. Our main contributions are a dataset extracted from Wikipedia that spans the past 120 years and a language model-based method that helps analyze how polarized a candidate is. Our data are divided into two parts, background information and political information about a candidate, since our hypothesis is that the political views of a candidate should be based …

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Multi-Scale Attention Networks For Pavement Defect Detection, Junde Chen, Yuxin Wen, Yaser Ahangari Nanehkaran, Defu Zhang, Adan Zeb Jul 2023

Multi-Scale Attention Networks For Pavement Defect Detection, Junde Chen, Yuxin Wen, Yaser Ahangari Nanehkaran, Defu Zhang, Adan Zeb

Engineering Faculty Articles and Research

Pavement defects such as cracks, net cracks, and pit slots can cause potential traffic safety problems. The timely detection and identification play a key role in reducing the harm of various pavement defects. Particularly, the recent development in deep learning-based CNNs has shown competitive performance in image detection and classification. To detect pavement defects automatically and improve effects, a multi-scale mobile attention-based network, which we termed MANet, is proposed to perform the detection of pavement defects. The architecture of the encoder-decoder is used in MANet, where the encoder adopts the MobileNet as the backbone network to extract pavement defect features. …

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Development And Calibration Of The Lmrpm Mid-Breton River Sediment Diversion Gate Operations, Emily E. Fertitta Jul 2023

Development And Calibration Of The Lmrpm Mid-Breton River Sediment Diversion Gate Operations, Emily E. Fertitta

LSU Master's Theses

With the rate of coastal land loss in Louisiana, the state is looking for innovative ways to help restore and maintain its coastal wetlands. Sediment diversions are going to be constructed along the Lower Mississippi River to mitigate the issues by diverting river water, sediment and nutrients into adjacent wetlands. Since there are currently no real-world applications of sediment diversions, the Lower Mississippi River Physical Model is a beneficial modeling tool to study the impact sediment diversions and relative sea level rise have on the hydraulics and sediment transport processes in the river. The two river sediment diversions on the …

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Signal Classification Based On Analog Computing Using Mems Network, Mohammad Okour Jul 2023

Signal Classification Based On Analog Computing Using Mems Network, Mohammad Okour

Durham School of Architectural Engineering and Construction: Dissertations, Theses, and Student Research

The rising complexity of machine learning algorithms and Artificial Intelligence in many applications, such as smart building, has prompted the development of alternate computing options. Because of their compact size, low power consumption, and diverse functionality, microelectromechanical systems (MEMS) have emerged as a possible candidate. This thesis focuses on using MEMS networks as computing units to classify a simple signal classification task using neural network methodology. The study intends to show the potential of using MEMS as an analog computing unit by discussing the advantage of the bi-stability pull-in behavior and hysteresis to create an accurate classifier of these waveforms. …

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A Natural Organic Artificial Synaptic Device Made From A Honey And Carbon Nanotube Admixture For Neuromorphic Computing, Md Mehedi Hasan Tanim, Zoe Templin, Kaleb Hood, Jun Jiao, Feng Zhao Jul 2023

A Natural Organic Artificial Synaptic Device Made From A Honey And Carbon Nanotube Admixture For Neuromorphic Computing, Md Mehedi Hasan Tanim, Zoe Templin, Kaleb Hood, Jun Jiao, Feng Zhao

Electrical and Computer Engineering Faculty Research & Creative Works

Artificial synaptic devices are the essential hardware component in emerging neuromorphic computing systems by mimicking biological synapse and brain functions. When made from natural organic materials such as protein and carbohydrate, they have potential to improve sustainability and reduce electronic waste by enabling environmentally friendly disposal. In this paper, a new natural organic memristor based artificial synaptic device is reported with the memristive film processed by a honey and carbon nanotube (CNT) admixture, that is, honey-CNT memristor. Optical microscopy, scanning electron microscopy, and micro-Raman spectroscopy are employed to analyze the morphology and chemical structure of the honey-CNT film. The device …

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Disentangling Groundwater Dynamics At Oregon's Mckenzie River Headwaters, Taylor Nicole Salazar Jul 2023

Disentangling Groundwater Dynamics At Oregon's Mckenzie River Headwaters, Taylor Nicole Salazar

Dissertations and Theses

Widespread mountain snowpack declines have been occurring across the western United States over the last century, and are increasing in duration and severity, with several record-breaking low-snowpack years in the last decade. In the Pacific Northwest, summer streamflow is largely a result of melting snow and groundwater discharge, as summers are typically dry and warm in this Mediterranean bioclimate, thus making spring-fed rivers critical for regional water resources. However, current trends and predictions in hydroclimate modeling indicate spring-fed rivers will experience reduced summer discharge driven by the increasingly larger impact of anthropogenic climate change (warming) on (decreased) mountain snowpack. A …

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Radical Urban Natures: Mitigating Urban Heat With Nature-Based Techniques In Portland, Oregon, Heather Day-Melgar Jul 2023

Radical Urban Natures: Mitigating Urban Heat With Nature-Based Techniques In Portland, Oregon, Heather Day-Melgar

Dissertations and Theses

Anthropogenic rising heat associated with climatic changes in the built environment has become a serious global issue. The built environment is often comprised of impermeable, paved surfaces, lack of vegetation to make way for development, tree removal, and loss or alteration of urban waterways, which leads to a degraded ecosystem for humans and non-human life, and less of an ability for carbon capture, all of which contribute to higher urban temperatures. This alteration of the existing natural environment leads to populations often unable to conceptualize that a built environment is still an ecosystem, and restoration is possible and necessary for …

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Practical Approaches And Guidance To Small Business Organization Cyber Risk And Threat Assessments, Stanley Mierzwa, Aneta Klepacka Jul 2023

Practical Approaches And Guidance To Small Business Organization Cyber Risk And Threat Assessments, Stanley Mierzwa, Aneta Klepacka

Center for Cybersecurity

Cyber-attacks and breaches can occur in any organization type, and the areas of small businesses are not exempt from this nefarious activity. This research note and rapid review provide various cybersecurity tools, guidelines, and frameworks that a small business can consider when embarking on the action to assess its cybersecurity hygiene and defensive stance. The content was pulled together in response to the need for an easy-to-digest approach that a small business utilizes to gain valuable confidence to undertake a self-assessment or third-party review of an organization’s cybersecurity plans. Regarding cybersecurity concerns, doing nothing is not an option, and taking …

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Experiential Learning And Exposure To Professional Experience In Civil Engineering Education, Sanjay Tewari Jul 2023

Experiential Learning And Exposure To Professional Experience In Civil Engineering Education, Sanjay Tewari

Civil, Architectural and Environmental Engineering Faculty Research & Creative Works

Experiential learning is increasingly recognized as a crucial component of modern education, especially in fields like civil engineering, where practical skills and real-world exposure are paramount. This paper explores the various avenues through which civil engineering education can offer professional exposure and experiential learning opportunities. By analyzing the impact of senior seminars, internships, co-ops, undergraduate research, study abroad programs, service learning, student design teams, leadership positions, and involvement in technical and professional student organizations, this paper aims to underscore the importance of these approaches in shaping well-rounded and industry-ready civil engineers.

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Ud Faculty And Students Collaborate With Air Force, Local Engineering Organization To Measure Atmospheric Turbulence At Different Heights, University Of Dayton Jul 2023

Ud Faculty And Students Collaborate With Air Force, Local Engineering Organization To Measure Atmospheric Turbulence At Different Heights, University Of Dayton

Blog: The Dayton Engineer

Dr. Miranda van Iersel, assistant professor in the Department of Electro-Optics and Photonics (EOP), along with graduate students Mohammad Albaqer Alghezi (EOP), Elaheh Ghanati Adams (EOP), Yujie Yang (EOP) and undergraduate student Scotty Campman (chemical engineering) recently conducted an experiment at the John Bryan State Park Observatory.

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Twin-Solute, Twin-Dislocation And Twin-Twin Interactions In Magnesium, Materials Yue, Jian Wang, Jian-Feng Nie Jul 2023

Twin-Solute, Twin-Dislocation And Twin-Twin Interactions In Magnesium, Materials Yue, Jian Wang, Jian-Feng Nie

Department of Mechanical and Materials Engineering: Faculty Publications

Magnesium alloys have received considerable research interest due to their lightweight, high specific strength and excellent castability. However, their plastic deformation is more complicated compared to cubic materials, primarily because their low-symmetry hexagonal closepacked (hcp) crystal structure. Deformation twinning is a crucial plastic deformation mechanism in magnesium, and twins can affect the evolution of microstructure by interacting with other lattice defects, thereby affecting the mechanical properties. This paper provides a review of the interactions between deformation twins and lattice defects, such as solute atoms, dislocations and twins, in magnesium and its alloys. This review starts with interactions between twin boundaries …

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Physiologically Relevant Fluid Shear Stress Induced Receptor Conversion In Hormone Receptor-Positive (Hr+) Breast Cancer, Jonathan James Cuccia Jul 2023

Physiologically Relevant Fluid Shear Stress Induced Receptor Conversion In Hormone Receptor-Positive (Hr+) Breast Cancer, Jonathan James Cuccia

LSU Doctoral Dissertations

Breast cancer is the most common type of cancer among all people in the United States as of 2023 and often has devastating impacts on afflicted patients. Although some treatments show great efficacy against primary breast tumors, none have been able to significantly reduce the mortality rate of breast cancer once it has metastasized to distant sites. In primary, hormone receptor-positive (HR+) breast cancers, endocrine therapies are often used as first-line treatments and are generally well-tolerated. However, as the disease progresses, these previously sensitive cancers can become resistant to endocrine therapies and continue proliferating despite them. Therefore, there is a …

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