Change Is The Only Constant: A Virtual Issue On Contemporary Catalysis, Shelley Minteer, Stephanie L. Brock, Géraldine Masson, Raymond E. Schaak

Chemistry Faculty Research & Creative Works

No abstract provided.

Changes In An Enzyme Ensemble During Catalysis Observed By High Resolution Xfel Crystallography, Nathan J. Smith, Medhanjali Dasgupta, David C. Wych, Cole Dolamore, Raymond G. Sierra, Stella Lisova, Darya Marchany-Rivera, Aina E. Cohen, Sébastien Boutet, Mark S. Hunter, Christopher Kupitz, Frédéric Poitevin, Frank R. Moss Iii, Aaron S. Brewster, Nicholas K. Sauter, Iris D. Young, Alexander M. Wolff, Virendra K. Tiwari, Nivesh Kumar, David B. Berkowitz, Ryan G. Hadt, Michael C. Thompson, Alec H. Follmer, Mark A. Wilson

Department of Chemistry: Faculty Publications

Enzymes populate ensembles of structures with intrinsically different catalytic proficiencies that are difficult to experimentally characterize. We use time-resolved mix-and-inject serial crystallography (MISC) at an X-ray free electron laser (XFEL) to observe catalysis in a designed mutant (G150T) isocyanide hydratase (ICH) enzyme that enhances sampling of important minor conformations. The active site exists in a mixture of conformations and formation of the thioimidate catalytic intermediate selects for catalytically competent substates. A prior proposal for active site cysteine charge-coupled conformational changes in ICH is validated by determining structures of the enzyme over a range of pH values. A combination of large …

Automated Lung Ultrasound Pulmonary Disease Quantification Using An Unsupervised Machine Learning Technique For Covid-19

Faculty, Staff and Student Publications

COVID-19 is an ongoing global health pandemic. Although COVID-19 can be diagnosed with various tests such as PCR, these tests do not establish pulmonary disease burden. Whereas point-of-care lung ultrasound (POCUS) can directly assess the severity of characteristic pulmonary findings of COVID-19, the advantage of using US is that it is inexpensive, portable, and widely available for use in many clinical settings. For automated assessment of pulmonary findings, we have developed an unsupervised learning technique termed the calculated lung ultrasound (CLU) index. The CLU can quantify various types of lung findings, such as A or B lines, consolidations, and pleural …

Social Networks, Access To Healthcare, And The Health-Related Quality Of Life Of Young Informal Workers In Nigeria’S Construction Industry, Ayomide Oluwaseyi Oladosu

Lingnan Theses (MPhil & PhD)

Young informal workers in Nigeria face a significant decline in their health-related quality of life (HRQoL) due to their lack of control over their employment conditions. This problem is particularly pronounced among young informal workers in the construction industry, given its precarious and hazardous nature. To enhance HRQoL, these workers primarily rely on their social networks for support. However, given the level of hazards they encounter in the construction industry, social networks alone may not be sufficient to directly improve their HRQoL. Nevertheless, social networks can facilitate access to healthcare, which in turn may enhance HRQoL. Unfortunately, limited research has …

The Impact Of Chatgpt On Student Learning/Performing, M. Samir Abou El-Seoud, Shehab Eldeen Ayman, Khaled A. Nagaty, Omar H. Karam

Computer Science

This paper explores the integration of ChatGPT, an AI-based language model, in undergraduate education. The study examines the potential benefits, challenges, and ethical considerations associated with incorporating ChatGPT into teaching and learning practices. It investigates the impact of ChatGPT on student engagement, critical thinking, and problem-solving skills, as well as its potential to enhance writing skills and provide personalized learning experiences. The survey conducted on faculty staff at a university reveals their perspectives on using ChatGPT, including its effects on learning outcomes and performance. Additionally, the paper addresses concerns related to biases in AI-generated content, privacy issues, copyright considerations, and …

Credit Hour Analysis, Tushar Ojha, Don R. Hush, Elias S. Lopez

Electrical & Computer Engineering Technical Reports

This report presents a detailed analysis of the credit hour usage pattern of undergraduate students at the University of New Mexico (UNM) using custom analytical tools. We introduce a credit-tree framework for analyzing credit hour efficiency. This framework leverages a custom-built specialized audit tool for categorizing student credits. More specifically, student credits are assigned to one of three categories: unusable credits that do not match any degree requirement, excess credits that can be removed without changing the requirement satisfaction, and applied credits that contribute to requirement satisfaction without excess. Clearly, this enables credit analysis at the course and degree requirement …

Demineralized Freeze-Dried Bovine Bone Xenograft Enhance Osteoblast Viability And Proliferation For Jaw Regeneration Materials, Feni Istikharoh, Sinta C. Wardani, Ariyati R. Pratiwi, Hidayat Sujuti, Edi Mustamsir

Journal of Dentomaxillofacial Science

Objectives The aim of this study was to analyze the viability and proliferation properties of the DFDBBX in MC3T3-E1 cell line Material and Methods Bovine was milled to reach nano sizes of 100-200 nm. We used 2 mg/mL, 4 mg/mL and 8 mg/mL to incubate MC3T3-E1 cells in the following experiment. Immunocytochemistry methods were performed using a Live/Dead cell imaging kit to investigate the viability of MC3T3-E1. To investigate the proliferation of MC3T3-E1, ICC was performed using an anti-Ki67 antibody. Using a confocal laser scanning microscope (CLSM), the cells were observed at LSIH Brawijaya University. Statistical analysis was performed using …

Osteocalcin Levels Evaluation Of Freeze-Dried Homologus Platelet-Rich Plasma In Periodontal Treatment, Niken Olivia, Kwartarini Murdiastuti

Journal of Dentomaxillofacial Science

Objective: The aim of this study was to evaluate enhanced osteocalcin levels by using freeze-dried homologous platelet-rich plasma (FD HPRP) in periodontal treatment to support the osteogenesis process.

Material and Methods: FD HPRP was made by HPRP from the blood bank, then freeze-drying and for sterilization, the γ-radiation process was carried out with doses of 20 and 25 kGy. The osteoblast (Cell line MG63) was cultured to confluent and then treated with FD HPRP 20 kGy, FD HPRP 25 kGy. Osteocalcin levels were tested using enzyme-linked immunosorbent assay (ELISA) on the 7th and 14th days. The data were analyzed using …

Labeling Piezo2 Activity In The Peripheral Nervous System, Nicholas W Villarino, Yasmeen M F Hamed, Britya Ghosh, Adrienne E Dubin, Amanda H Lewis, Max A Odem, Meaghan C Loud, Yu Wang, M Rocio Servin-Vences, Ardem Patapoutian, Kara L Marshall

Duncan NRI Faculty and Staff Publications

Sensory neurons detect mechanical forces from both the environment and internal organs to regulate physiology. PIEZO2 is a mechanosensory ion channel critical for touch, proprioception, and bladder stretch sensation, yet its broad expression in sensory neurons suggests it has undiscovered physiological roles. To fully understand mechanosensory physiology, we must know where and when PIEZO2-expressing neurons detect force. The fluorescent styryl dye FM 1-43 was previously shown to label sensory neurons. Surprisingly, we find that the vast majority of FM 1-43 somatosensory neuron labeling in mice in vivo is dependent on PIEZO2 activity within the peripheral nerve endings. We illustrate the …

Enhanced Cerebroprotection Of Xenon-Loaded Liposomes In Combination With Rtpa Thrombolysis For Embolic Ischemic Stroke, Tao Peng, Keith Booher, Melanie R Moody, Xing Yin, Jaroslaw Aronowski, Sean I Savitz, Shao-Ling Huang

Faculty, Staff and Student Publications

Xenon (Xe) has shown great potential as a stroke treatment due to its exceptional ability to protect brain tissue without inducing side effects. We have previously developed Xe-loaded liposomes for the ultrasound-activated delivery of Xe into the cerebral region and demonstrated their therapeutic efficacy. At present, the sole FDA-approved thrombolytic agent for stroke treatment is recombinant tissue plasminogen activator (rtPA). In this study, we aimed to investigate the potential of combining Xe-liposomes with an intravenous rtPA treatment in a clinically relevant embolic rat stroke model. We evaluated the combinational effect using an in vitro clot lysis model and an in …

Liposome-Based Carriers For Crispr Genome Editing, Shao-Ling Huang

Faculty, Staff and Student Publications

The CRISPR-based genome editing technology, known as clustered regularly interspaced short palindromic repeats (CRISPR), has sparked renewed interest in gene therapy. This interest is accompanied by the development of single-guide RNAs (sgRNAs), which enable the introduction of desired genetic modifications at the targeted site when used alongside the CRISPR components. However, the efficient delivery of CRISPR/Cas remains a challenge. Successful gene editing relies on the development of a delivery strategy that can effectively deliver the CRISPR cargo to the target site. To overcome this obstacle, researchers have extensively explored non-viral, viral, and physical methods for targeted delivery of CRISPR/Cas9 and …

Full Issue

Insights: The Newsletter of the Neal A. Maxwell Institute for Religious Scholarship

No abstract provided.

Brown Bag Lectures Continue To Inform

Insights: The Newsletter of the Neal A. Maxwell Institute for Religious Scholarship

Two outstanding Brown Bag lectures were presented in February. Louis C. Midgley, professor of Political Science at BYU, discussed "The Authorship Debate: Who Really Wrote the Book of Mormon?" This lecture was based on a paper Midgley has submitted for publication in a new FARMS collection of essays on the authorship issue. Midgley gave a history of attempts to dismiss Joseph Smith's explanation for the coming forth of the Book of Mormon. In his paper, Midgley writes: "Those who fashion ... naturalistic explanations [of the Book of Mormon's origin] are faced with, among other challenges, the task of uncovering in …

New Committees Will Set Media And Electronic Policies

Insights: The Newsletter of the Neal A. Maxwell Institute for Religious Scholarship

FARMS has formed two new committees to give the Foundation guidance on nonprint forms of distribution. As opportunities grow to disseminate faithful scholarship on the Book of Mormon and related subjects through new means, the Foundation wants to be ready to respond appropriately.

Farms Audiovisual Materials Can Be Found In Video Stores And Libraries

Insights: The Newsletter of the Neal A. Maxwell Institute for Religious Scholarship

FARMS is now providing some public libraries and video rental stores with copies of videos, audiotapes, and transcripts of Hugh Nibley's Teachings of the Book of Mormon course videos and the FARMS Book of Mormon Lecture Series, as part of its mission to make Book of Mormon research findings available widely, promptly, and economically.

Farms, Oxford University Press, And E. J. Brill Join In Publishing Venture

Insights: The Newsletter of the Neal A. Maxwell Institute for Religious Scholarship

The Foundation for Ancient Research and Mormon Studies is in the last stages of negotiating an agreement with Oxford University Press and E. J. Brill (in the Netherlands) to jointly publish The Dead Sea Scrolls Electronic Reference Library. The FARMS Dead Sea Scrolls Electronic Database, currently under development with technical assistance from BYU, will be published as volume 2 in the series. Volume 1, a collection on disk of high resolution digitized images of some of the nonbiblical scrolls and scroll fragments that Oxford has been working on for some time, is scheduled for demonstration at the "International Symposium …

Complete Issue - Vol. 77, No. 3 And 4

Journal of Mississippi History

No abstract provided.

Book Reviews, Aaron Mcarthur, Chris Danielson, William P. Hustwit, Kevin Boland Johnson, Leslie K. Poole, Keith S. Hébert

Journal of Mississippi History

Book reviews of:

Telling Our Stories: Museum of Mississippi History and Mississippi Civil Rights Museum By Mississippi Department of Archives and History Jackson: University Press of Mississippi, 2017. Acknowledgments, foreword, introduction, illustrations, index. 200 pages (approx.), $25.00 cloth. ISBN: 9781496813480.

A Chance for Change: Head Start and Mississippi’s Black Freedom Struggle. By Crystal R. Sanders. (Chapel Hill: University of North Carolina Press, 2016. Acknowledgements, illustrations, map, notes, bibl., index. Pp. xi, 266. $27.95 paper. ISBN: 978-1-4696- 2780-9.)

Brown v. Board and the Transformation of American Culture: Education and the South in the Age of Desegregation. By Ben Keppel. …

A Celebration 100 Years In The Making: The Modernization Of Davis Wade Stadium At Scott Field From 1914 To 2014, Adam G. Pfleegor, Chad S. Seifried

Journal of Mississippi History

No abstract provided.

Vaught-Hemingway Stadium At Hollingsworth Field And Ole Miss: 100 Years In The Making, Chad S. Seifried, Milorad M. Novicevic

Journal of Mississippi History

No abstract provided.

Sol Street: Confederate Partisan Leader, Andrew Brown

Journal of Mississippi History

No abstract provided.

Complete Issue - Vol. 79, No. 1 And 2

Journal of Mississippi History

No abstract provided.

Logging And Rafting Timber In South Mississippi, 1840-1910, Nollie W. Hickman

Journal of Mississippi History

No abstract provided.

Mississippi's Confederate Leaders After The War, William B. Hesseltine, Larry Gara

Journal of Mississippi History

No abstract provided.

Mississippi Unionism: The Case Of The Reverend James A. Lyon, John K. Bettersworth

Journal of Mississippi History

No abstract provided.

Introduction, Dennis J. Mitchell

Journal of Mississippi History

No abstract provided.

Mississippi Historical Society Minutes Of The Annual Business Meeting, March 4, 2017

Journal of Mississippi History

No abstract provided.

The University Of Mississippi, The Board Of Trustees, Students, And Slavery: 1848-1860, Elias J. Baker

Journal of Mississippi History

No abstract provided.

The Impact Of Covid-19 On Collaboration Between School Psychologists And Board-Certified Behavioral Analysts, Taylor Bronaugh

Department of Graduate Psychology - Masters Theses

The aim of this paper is to examine the impact of communication styles brought on by distanced learning and its effect on collaboration for school psychologists and Bord Certified Behavioral Analysts (BCBAs). Prior studies have addressed collaboration habits between these school-based professionals. The current study aims to analyze the impact that COVID-19 had on these practitioners’ collaboration habits and to investigate their current communication and collaboration habits. A mixed methods locally developed anonymous survey was created and used for data collection. Participants were recruited through social-media groups and via word-of-mouth sharing. 20 school-based practitioners shared their perceptions and experiences with …

Editorial: Innovative, Non-Conventional Ingredients For Sustainable Aquafeeds, Janice A. Ragaza, Vikas Kumar, Rex Ferdinand M. Traifalgar

Biology Faculty Publications

No abstract provided.