Digital Commons Network^™

Ergosterol Distribution Controls Surface Structure Formation And Fungal Pathogenicity, Hau Lam Choy, Elizabeth A. Gaylord, Tamara L. Doering

2020-Current year OA Pubs

Ergosterol, the major sterol in fungal membranes, is critical for defining membrane fluidity and regulating cellular processes. Although ergosterol synthesis has been well defined in model yeast, little is known about sterol organization in the context of fungal pathogenesis. We identified a retrograde sterol transporter, Ysp2, in the opportunistic fungal pathogen

Loss Of Stearoyl-Coa Desaturase 2 Disrupts Inflammatory Response In Macrophages, Joseph B. Lin, Amy Mora, Tzu Jui Wang, Andrea Santeford, Darksha Usmani, Marianne M. Ligon, Indira U. Mysorekar, Rajendra S. Apte

2020-Current year OA Pubs

Macrophages are innate immune cells that patrol tissues and are the first responders to detect infection. They orchestrate the host immune response in eliminating invading pathogens and the subsequent transition from inflammation to tissue repair. Macrophage dysfunction contributes to age-related pathologies, including low-grade inflammation in advanced age that is termed "inflammaging." Our laboratory has previously identified that macrophage expression of a fatty acid desaturase, stearoyl-CoA desaturase 2 (SCD2), declines with age. Herein, we delineate the precise cellular effects of SCD2 deficiency in murine macrophages. We found that deletion of

Investigating The Rheological Behavior Of A Simple Yield Stress Fluid Under Shear Flows, Francesco Accetta

Theses

Many soft materials display unique and complex rheological behavior characterized by a transition from a solid-like to a fluid-like state upon the application of a force that exceeds the threshold to flow, known as the yield stress. Yield stress fluids are found in a wide range of commonly encountered materials including microgels, emulsions, and foams, and have been widely studied by rheologists over the last several decades. Carbopol is a popular polymeric microgel system as it displays simple, non-thixotropic rheological behavior and is typically seen as an ideal yield stress fluid. Previous research has demonstrated the reproducible behavior of shear …

Loss Of Stearoyl-Coa Desaturase 2 Disrupts Inflammatory Response In Macrophages, Andrea Santeford, Darksha Usmani, Marianne M Ligon, Indira U Mysorekar, Rajendra S Apte

Faculty, Staff and Students Publications

Macrophages are innate immune cells that patrol tissues and are the first responders to detect infection. They orchestrate the host immune response in eliminating invading pathogens and the subsequent transition from inflammation to tissue repair. Macrophage dysfunction contributes to age-related pathologies, including low-grade inflammation in advanced age that is termed "inflammaging." Our laboratory has previously identified that macrophage expression of a fatty acid desaturase, stearoyl-CoA desaturase 2 (SCD2), declines with age. Herein, we delineate the precise cellular effects of SCD2 deficiency in murine macrophages. We found that deletion of

Women, Children, And Tobacco, Desti Yuwastina

JURNAL KOMUNIKASI INDONESIA

Tobacco has been a well-known commodity in Indonesia, especially since kretek has attracted immense attention to be sold internationally. Both tobacco farms and tobacco industry have also been subjected to the undesirable circumstances of tobacco within the range of national and international frameworks. This research aspires to uncover the health perspective of tobacco smoking activities by underpinning the questionable way of nurturing children in the surroundings of tobacco as a way of protection towards the future of the tobacco industry. In order to unravel the novelty of the research on the subordinate roles of women and children, an enormous proportion …

The Impact Of Digital Communication On Online Purchasing Behavior Among Indonesian Millennials: A Case Study Of Tokopedia, Erwin Panigoro, Yuli Harwani, Dudi Permana, Erna Sofriana Imaningsih, Erlina P. Mahadewi

JURNAL KOMUNIKASI INDONESIA

This article discusses the impact of digital communication on the online purchasing behavior of millennials in Indonesia, with a particular focus on transaction flow through the online commerce platform Tokopedia. The study aims to show that Tokopedia's digital communications determine users' attitudes and purchasing behavior. In this paper, the quantitative research method of causal design is adopted, and 210 respondents selected by simple random sampling are used as the sample size. The variables examined in this study include perceptions related to digital communication and online purchasing behavior, which are manipulated through different dimensions and indicators. The results show that perceived …

Writing As A Mean To Rehabilitate The Traumatized Self In Vivre Vite By Brigitte Giraud, Nadia Naboulsi Iskandarani

BAU Journal - Society, Culture and Human Behavior

In her novel Vivre vite, Brigitte Giraud writes the story of a disaster that obsesses her: on June 22, 1999; her companion Claude died in a motorcycle accident in Lyon. This vehicle, a powerful and dangerous Honda, was prohibited on Japanese territory and was reserved for export to Europe. It did not belong to Claude, but to the writer's brother. She was only able to return to the drama that inhabited her in 2022, that is to say twenty-three years after Claude's death. The reader cannot help but wonder about this long silence and why this return to the minutiae …

Impact Of Perceived Organizational Support, Employee Empowerment, And Organizational Commitment On Turnover Intention In The Lebanese Smes Sector: The Mediating Role Of Employee Engagement, Istivani Hilal

BAU Journal - Society, Culture and Human Behavior

This study investigates the impact of perceived organizational support (POS), employee empowerment (EE), and organizational commitment (OC) on turnover intention (TI) in the Lebanese small and medium-sized enterprises (SMEs) sector. The study also examines the mediating role of employee engagement (EEG) in this relationship. A sample of 390 employees from SMEs in Lebanon was surveyed using a structured questionnaire. The data were analyzed using structural equation modeling (SEM). The results show that POS, EE, and OC are negatively related to TI in the Lebanese SMEs sector. Moreover, EEG mediates the relationship between POS, EE, and OC and TI. Specifically, the …

Some Reason Prevalence Of Anxiety And Depression Among People Of Different Ages: A Review, Sarah H. Shaalan, Rana Neama Atiya, Shaden M.H. Mubarak, Sahar Aqeel Hussain

Maaen Journal for Medical Sciences

Depression is a widespread, chronic clinical illness that affects thoughts, attitudes, and actual wellbeing. Low spirits, a lack of energy, resentment, sleepiness, and an inability to appreciate life are some signs of it. In any event, clinical investigations to date have demonstrated that dejected people don't respond well to treatment. Therefore, in this exceptional issue, we will purposefully examine sadness at the conduct level, with a special focus on a few fascinating points, such as "The study of disease transmission of sadness and constant clinical illness Potential components that included 'differences in sexual orientation,' 'age contrasts,' 'impact on social factors,' …

Eplerenone Crystal Nanosuspension For Solubility Enhancement: Preparation And Evaluation, Hawraa K. Khafeef, Nawal A. Rajab

Maaen Journal for Medical Sciences

Eplerenone is an aldosterone receptor inhibitor utilized for management of hypertension and chronic heart failure. However, it’s low solubility and dissolution-dependent absorption lead to reduced oral bioavailability (The absolute bioavailability of eplerenone is 69%). This study aimed to develop and optimize eplerenone nanosuspension (EPLNS) to enhance its solubility and improve dissolution rate. The nanosuspension (NS) was produced using the solvent anti-solvent precipitation method, and an investigation was conducted to assess the effect of variables such as stabilizer type, stabilizer concentration, and stirring rate on particle size (PS) and polydispersity index (PDI). The results showed that most of the prepared EPLNS …

Predictive Diabetes Mellitus From Dna Sequences Using Deep Learning, Lena Abed Alraheim Hamza, Hussein Attya Lafta, Sura Zaki Al-Rashid

Al-Bahir

Diabetes is a chronic metabolic disorder characterized by elevated blood sugar levels. It manifests in different forms, with type 1 and type 2 being the most prevalent. Type 1 diabetes results from the autoimmune destruction of insulin-producing cells, whereas type 2 diabetes primarily stems from insulin resistance. Despite advancements in treatment, accurate detection and prediction of diabetes remain challenging. Early diagnosis is crucial for effective management and prevention of complications. Another obstacle lies in interpreting vast amounts of health data, including DNA sequencing, which poses difficulties for healthcare professionals in identifying relevant patterns and associations. Artificial intelligence (AI) holds promise …

Impact Of Orthodontic Adhesive Magnets On Degree Of Conversion And The Kinetics Of Polymerization, Saud Khalil Al Hauly, Mazin Ahmed, Sarmad S. S. Al Qassar

Al-Bahir

The purpose of this study was to investigate the effects of storing uncured photopolymerized dental adhesive in a magnetic field on their kinetics of polymerization and degree of conversion (DC%). Method: Vage Ortho Uv orthodontic adhesive was used in this experiment. Under constant frequency (50Hz), the applied magnetic field was used at two different intensities (fixed at 0.01T and 0.05T) for 5 minutes each. Using Fourier transform infrared spectroscopy (FTIR-ATR), the degree of conversion (DC%) and polymerization kinetics were assessed. Results: There was a clear improvement in the results when compared to the control, the DC% mean tends to increase …

(2012) Group Physical Exercise, Relationship Dynamics, And Curative Factors: Qualitative Findings From A Kinesiology Exercise Immunology Course, Laura Fazio-Griffith, Jennifer R. Curry

Louisiana Journal of Counseling

Qualitative inquiry was used to examine students’ perceptions of, and experiences in, a Kinesiology Exercise Immunology Course with an experiential marathon training component. Twenty-eight students participated in four focus groups. Data was analyzed according to the themes and patterns that emerged during each focus group. Major themes revealed the presence of, relationship dynamics, interpersonal learning, and multiple curative factors used to develop and enhance the relationship of the educator and student the experiential classroom setting. Implications and recommendations for human service educators are discussed.

On-Line Discussions About Self-Injury And Suicide, Jennifer Marshall, Trey Fitch

Louisiana Journal of Counseling

College students were surveyed regarding their use of websites and BLOG/discussion boards that promote and/or discourage and treat suicidal and self-injurious behavior. The students surveyed related that they were more likely to use websites and BLOG/discussion boards that discourage and treat suicidal and self-injurious behaviors. The results also indicated that the respondents had a higher percentage of response to acknowledging that peers have been influenced by websites/discussion boards/BLOGS that encourage suicidal and self-injurious behaviors. Overall, these findings support the notion that the viewing of harmful self-injury websites is not widespread.

(2012) Entire Issue, Meredith Nelson, Peter Emerson

Louisiana Journal of Counseling

No abstract provided.

The Gazette August 30, 2023, Langston University

LU Gazette, 2020-2029

The student newspaper for Langston University

Aldersgate North Charleston Minutes Vol. 9, Aldersgate United Methodist Church

Methodist Local Church Records

No abstract provided.

Architecture, Construction, Retention, And Repair Of Faecal Shields In Three Tribes Of Tortoise Beetles (Coleoptera, Chrysomelidae, Cassidinae: Cassidini, Mesomphaliini, Spilophorini), Caroline Simmrita Chaboo, Sally Adam, Kenji Nishida, Luke Schletzbaum

University of Nebraska State Museum: Entomology Papers

Animal constructions are the outcomes of complex evolutionary, behavioural, and ecological forces. A brief review of diverse animal builders, the materials used, and the functions they provide their builders is provided to develop approaches to studying faecal-based constructions and faecal-carrying in leaf beetles (Coleoptera: Chrysomelidae). Field studies, rearing, dissections, photography, and films document shields constructed by larvae in two species in two tribes of the subfamily Cassidinae, Calyptocephala attenuata (Spaeth, 1919) (Spilophorini), and Cassida sphaerula Boheman, 1853 (Cassidini). Natural history notes on an undetermined Cassidini species and Stolas cucullata (Boheman, 1862) (Tribe Mesomphaliini) outline the life cycle of tortoise beetles …

Spartan Daily, August 30, 2023, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2023

Volume 161, Issue 05

Brad Rush V. City Of Philadelphia

2023 Decisions

USDC for the Eastern District of Pennsylvania

Bertumbuh Berkembang: Modul Pelatihan Pendidik Paud, Hani Yulindrasari

Pengembangan Profesional

Modul Pendidik PAUD-HI ini memaparkan berbagai aspek perkembangan anak yang dibagi ke dalam indikator pencapaian per kategori umur di 6 area perkembangan yang mengacu kepada Standar Tingkat Pencapaian Perkembangan Anak (STTPA). Pembelajaran inklusi, pembelajaran berbasis bermain, serta cara komunikasi postif juga dijelaskan dalam modul yang disusun khusus untuk pendidik PAUD.

This module written in Indonesian Bahasa has been developed for Early Childhood Educators and describes key aspects of children's development. It is divided into achievement indicators by age in 6 areas of development referred to in the Standard Levels of Achievement of the Development of Children (in Indonesian: STTPA). Creating …

Curriculum Subcommittee Agenda September 7, 2023, Utah State University

Educational Policies Committee

• Approval of Minutes - April 6, 2023
• Program Proposals
• Semester Course Approval Reviews
• Other Business - New baccalaureate programs template and cross/dual listed info for the EPC handbook
• Adjourn: 3:00 pm

Unh Researchers Awarded Close To $3 Million To Develop Sustainable In-Space Manufacturing, Robbin Ray

Media Relations

No abstract provided.

Deep Learning-Based Predictive Model Of Mrna Vaccine Deterioration: An Analysis Of The Stanford Covid-19 Mrna Vaccine Dataset, Nisreen Sulayman

Baghdad Science Journal

The emergence of SARS-CoV-2, the virus responsible for the COVID-19 pandemic, has resulted in a global health crisis leading to widespread illness, death, and daily life disruptions. Having a vaccine for COVID-19 is crucial to controlling the spread of the virus which will help to end the pandemic and restore normalcy to society. Messenger RNA (mRNA) molecules vaccine has led the way as the swift vaccine candidate for COVID-19, but it faces key probable restrictions including spontaneous deterioration. To address mRNA degradation issues, Stanford University academics and the Eterna community sponsored a Kaggle competition.This study aims to build a deep …

The Relaying Network In Free-Space Optical Communications Using Optical Amplifiers In Cascaded Configuration, Ucuk Darusalam, Arockia Bazil Raj, Fitri Yuli Zulkifli, Purnomo Sidi Priambodo, Eko Tjipto Rahardjo

Makara Journal of Technology

Optical relaying is the best technique to implement free-space optical (FSO) communications as a terrestrial platform. However, atmospheric turbulence (AT) limits the optical-propagation path length. In this study, the implementation of some optical amplifiers (OAs) in cascaded configuration, namely, erbium-doped fiber amplifiers, semiconductor OAs, and Raman amplifiers (RAs), are investigated through simulation. This study aims to search for the maximum link distance of an optical propagation and enhance the FSO performance caused by each configuration of OAs. The optical relaying network consists of three nodes, with each node designed with a space of several kilometers under the influence of AT. …

Atmospheric Pressure Plasma Treatment Of Skin: Penetration Into Hair Follicles, Kseniia Konina, Theresa A. Freeman, Mark J. Kushner

Department of Orthopaedic Surgery Faculty Papers

Sterilization of skin prior to surgery is challenged by the reservoir of bacteria that resides in hair follicles. Atmospheric pressure plasma jets (APPJs) have been proposed as a method to treat and deactivate these bacteria as atmospheric plasmas are able to penetrate into structures and crevices with dimensions similar to those found in hair follicles. In this paper, we discuss results from a computational investigation of an APPJ sustained in helium flowing into ambient air, and incident onto a layered dielectric similar to human skin in which there are idealized hair follicles. We found that, depending on the location of …

Improving Irrigant Flow Characteristics For Enhanced Root Canal Therapy: A Numerical Study, Bibek Banjaday

Masters Theses

This numerical study investigates the flow characteristics within a root canal during a manual endodontic treatment. To underscore the difference in root canal geometry, a simplified root canal (frustum of a cone) and a more complex (realistic) root canal geometry were considered. The needle utilized in all simulations is a side-vented 30G KerrHaweIrrigation Probe, KerrHawe SA, Bioggio, Switzerland. For both root canal geometries, the effect of variation of fluid inlet velocity, needle insertion depth, and needle tilt angle on flow characteristics was examined via velocity contours, turbulent intensity, wall shear stress, and streamline and vector plots. The fluid was Sodium …

My Brother’S Keeper: Two Black Men Navigating The Tenure-Track Experience, Danny E. Malone Jr., Jesse R. Ford

Sociology

This study explores the tenure-track experiences of two junior faculty Black men in higher education, while growing still remains vastly unexplored in higher education. Using an autoethnography approach with a critical race theory lens, the authors explore how race and institutional expectations shape their experiences along the primary components of the tenure process: research, teaching and service. While one author is beginning their tenure journey while the other is ending, findings highlight commonalities along teaching and service experiences are being mediated by their identities as Black men. Their research experiences are distinct from one another given the different research expectations …

Valuing Social Data, Amanda Parsons, Salomé Viljoen

Law & Economics Working Papers

Social data production is a unique form of value creation that characterizes informational capitalism. Social data production also presents critical challenges for the various legal regimes that are encountering it. This Article provides legal scholars and policymakers with the tools to comprehend this new form of value creation through two descriptive contributions. First, it presents a theoretical account of social data, a mode of production which is cultivated and exploited for two distinct (albeit related) forms of value: prediction value and exchange value. Second, it creates and defends a taxonomy of three “scripts” that companies follow to build up and …

Optimization Of A Bioreactor, Ali Alshami

AI Assignment Library

The primary objective of this assignimentis to learn to work effectively as a team, and to design an experiment where optimization is essential.