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The Impact Of The Architectural Design Of Kindergarten Buildings On The Formation Of The Identity Of The Child, Eman Ahmed Ebrahim, Ahmed Eltantawy Elmadawy, Asmaa Nasr El-Din Elbadrawy

Mansoura Engineering Journal

The stage of human childhood is one of the important stages in a person’s life. At this stage, the child’s abilities grow, his talents become clear, and all the possibilities of his physical, emotional, social and mental personality open up. This stage represents the cornerstone of the growth of psychological functions in the following years. Therefore, taking care of childhood and paying attention to its activities is one of the most important influences that contribute to the progress of societies, and there is no doubt that the process of growth for the child takes place during the child’s interaction with …

Contactless System And Method For Assessing Tissue Viability And Other Hemodynamic Parameters, Michele Pierro, Kyle Quinn, Alan Woessner

Patents Granted

A contactless system for assessing tissue viability and other hemodynamic parameters includes one or more light sources configured to emit lights at a predetermined wavelength sensitive to hemoglobin concentration associated with spontaneous hemodynamic oscillations at tissue in a predetermined area of a human subject. One or more polarizers are each coupled to one or more of the one or more light sources and are configured to polarize the light to a polarized state such that the polarized light in the polarized state diffuses into the tissue in the predetermined area at a predetermined depth and the polarized light is maintained …

Approval For: Discharge System 2022 Annual Operations And Maintenance Report, Berkeley Pit And Discharge Pilot Project, Dated May 26, 2023, Nikia Greene

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.

Chem 339-001-003-101: Analytical Physical Lab, Chunyan Liu

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Em 631-852: Legal Aspects In Environmental Engineering, Michael Bonchonsky

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Evsc 610-101: Environmental Chemical Science, Lijie Zhang

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Evsc 791-001 And Chem 791-001: Graduate Seminar, Sara Casado Zapico

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 221-101: Analytical Methods, Chunyan Liu

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

The Molecular Biophysics Of Extracellular Vimentin And Its Role In Pathogen–Host Interactions, Sepideh Parvanian, Leila S. Coelho-Rato, John E. Eriksson, Alison E. Patteson

Physics - All Scholarship

Vimentin, an intermediate filament protein typically located in the cytoplasm of mesenchymal cells, can also be secreted as an extracellular protein. The organization of extracellular vimentin strongly determines its functions in physiological and pathological conditions, making it a promising target for future therapeutic interventions. The extracellular form of vimentin has been found to play a role in the interaction between host cells and pathogens. In this review, we first discuss the molecular biophysics of extracellular vimentin, including its structure, secretion, and adhesion properties. We then provide a general overview of the role of extracellular vimentin in mediating pathogen-host interactions, with …

System And Method For Robust, Modular, Product Sensitive Monitoring And Encoding Of Quality And Safety Along The Perishable Supply Chain, Ismail Uysal, Frederick Louis Wu

USF Patents

A system and method for assessing a supply chain for a perishable product. In various embodiments, the present invention provides a quality code for a perishable product which encodes a plurality of the most important performance metrics of the cold chain for the perishable product, including food quality oriented measures such as cut-to-cool time, transportation quality and accumulated shelf-life loss, and food safety oriented measures such as most probable number range for microorganism growth into a compact, modular and simple to read format.

Evolutionary Action-Machine Learning Model Identifies Candidate Genes Associated With Early-Onset Coronary Artery Disease, Dillon Shapiro, Kwanghyuk Lee, Jennifer Asmussen, Thomas Bourquard, Olivier Lichtarge

Faculty, Staff and Students Publications

Background Coronary artery disease is a primary cause of death around the world, with both genetic and environmental risk factors. Although genome-wide association studies have linked >100 unique loci to its genetic basis, these only explain a fraction of disease heritability. Methods and Results To find additional gene drivers of coronary artery disease, we applied machine learning to quantitative evolutionary information on the impact of coding variants in whole exomes from the Myocardial Infarction Genetics Consortium. Using ensemble-based supervised learning, the Evolutionary Action-Machine Learning framework ranked each gene's ability to classify case and control samples and identified 79 significant associations. …

Lem2 Is Essential For Cardiac Development By Maintaining Nuclear Integrity, Jacob A Ross, Didier Hodzic, Et Al.

2020-Current year OA Pubs

AIMS: Nuclear envelope integrity is essential for the compartmentalization of the nucleus and cytoplasm. Importantly, mutations in genes encoding nuclear envelope (NE) and associated proteins are the second highest cause of familial dilated cardiomyopathy. One such NE protein that causes cardiomyopathy in humans and affects mouse heart development is Lem2. However, its role in the heart remains poorly understood.

METHODS AND RESULTS: We generated mice in which Lem2 was specifically ablated either in embryonic cardiomyocytes (Lem2 cKO) or in adult cardiomyocytes (Lem2 iCKO) and carried out detailed physiological, tissue, and cellular analyses. High-resolution episcopic microscopy was used for three-dimensional reconstructions …

Neighborhood Disadvantage And Neural Correlates Of Threat And Reward Processing In Survivors Of Recent Trauma, E Kate Webb, Stacey L House, Et Al.

2020-Current year OA Pubs

IMPORTANCE: Differences in neighborhood socioeconomic characteristics are important considerations in understanding differences in risk vs resilience in mental health. Neighborhood disadvantage is associated with alterations in the function and structure of threat neurocircuitry.

OBJECTIVE: To investigate associations of neighborhood disadvantage with white and gray matter and neural reactivity to positive and negative stimuli in the context of trauma exposure.

DESIGN, SETTING, AND PARTICIPANTS: In this cross-sectional study, survivors of trauma who completed sociodemographic and posttraumatic symptom assessments and neuroimaging were recruited as part of the Advancing Understanding of Recovery After Trauma (AURORA) study between September 2017 and June 2021. Data …

Chem 221-001: Analytical Methods, Mustansar Hussain

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Evsc 335-001: Environmental Law, Michael Bonchonsky

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 301-101: Chemical Technology, Xianyang Meng

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Chem 360-001: Environmental Chemistry, Alexei Khalizov

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Eps 202-101-Hm1: Society, Technology And Environment, Zeyuan Qiu

Chemistry, Environmental and Forensic Science Syllabi

No abstract provided.

Structured Ethical Review For Wastewater-Based Testing In Support Of Public Health, Devin A. Bowes, Amanda Darling, Erin M. Driver, Devrim Kaya, Rasha Maal-Bared, Lisa M. Lee, Kenneth Goodman, Sangeet Adhikari, Srijan Aggarwal, Aaron Bivins, Zuzana Bohrerova, Alasdair Cohen, Claire Duvallet, Rasha A. Elnimeiry, Justin M. Hutchison, Vikram Kapoor, Ishi Keenum, Fangqiong Ling, Deborah Sills, Ananda Tiwari, Peter Vikesland, Ryan Ziels, Cresten Mansfeldt

Faculty Publications

Wastewater-based testing (WBT) for SARS-CoV-2 has rapidly expanded over the past three years due to its ability to provide a comprehensive measurement of disease prevalence independent of clinical testing. The development and simultaneous application of WBT measured biomarkers for research activities and for the pursuit of public health goals, both areas with well-established ethical frameworks. Currently, WBT practitioners do not employ a standardized ethical review process, introducing the potential for adverse outcomes for WBT professionals and community members. To address this deficiency, an interdisciplinary workshop developed a framework for a structured ethical review of WBT. The workshop employed a consensus …

Transcriptional Pausing Factor M1bp Regulates Cellular Homeostasis By Suppressing Autophagy And Apoptosis In Drosophila Eye, Anuradha Venkatakrishnan Chimata, Hannah Darnell, Akanksha Raj, Madhuri Kango-Singh

Biology Faculty Publications

During organogenesis cellular homeostasis plays a crucial role in patterning and growth. The role of promoter proximal pausing of RNA polymerase II, which regulates transcription of several developmental genes by GAGA factor or Motif 1 Binding Protein (M1BP), has not been fully understood in cellular homeostasis. Earlier, we reported that M1BP, a functional homolog of ZKSCAN3, regulates wingless (wg) and caspase-dependent cell death (apoptosis) in the Drosophila eye. Further, blocking apoptosis does not fully rescue the M1BP^RNAi phenotype of reduced eye. Therefore, we looked for other possible mechanism(s). In a forward genetic screen, members of the Jun-amino-terminal-(NH2)-Kinase (JNK) pathway …

A General Effectiveness-Ntu Modeling Framework For Membrane Dehumidification Systems, Andrew J. Fix, James E. Braun, David M. Warsinger

School of Mechanical Engineering Faculty Publications

Selective membrane dehumidification is a promising technology for energy efficient air dehumidification in buildings and has been ranked as a top alternative technology by the Department of Energy. One critical area that needs to be addressed is system modeling that incorporates device mass transfer characteristics and sizing. This work develops, validates, and applies a simple effectiveness-number of transfer units (𝜀−𝑁TU) modeling framework for dehumidification technologies that can be used to predict performance and determine required membrane area for a wide range of technologies, including energy recovery ventilators, vacuum membrane dehumidification, and desiccant dehumidifiers. Although the 𝜀−𝑁TU method is a well-established …

Chimes: September 5, 2023, Calvin University

Chimes

"There's a hopefulness in building": Enrollment and morale increases at Calvin despite lingering questions by Savannah Shustack & Maya Oeverman

New options for students as Calvin admin renews ties with South Korean colleges by Ethan Meyers

Dining services working towards a change by Ashley Hamons

Calvin football's recruitment process succeeds by Dillion Baumchen

Alternative study spaces by Lauren Nyong

School of Health continues to establish a presence on campus by Jacob Westra

Library renovations will integrate academic and community resources by Savannah Shustack

For healthy growth, change must come hand-in-hand with stability by Savannah Shustack

Epidermal Growth Factor Receptor-Targeted Neoantigen Peptide Vaccination For The Treatment Of Non-Small Cell Lung Cancer And Glioblastoma, Fenge Li, Huancheng Wu, Xueming Du, Yimo Sun, Barbara Nassif Rausseo, Amjad Talukder, Arjun Katailiha, Lama Elzohary, Yupeng Wang, Zhiyu Wang, Gregory Lizée

Faculty, Staff and Student Publications

The epidermal growth factor receptor (EGFR) plays crucial roles in several important biological functions such as embryogenesis, epithelial tissue development, and cellular regeneration. However, in multiple solid tumor types overexpression and/or activating mutations of the EGFR gene frequently occur, thus hijacking the EGFR signaling pathway to promote tumorigenesis. Non-small cell lung cancer (NSCLC) tumors in particular often contain prevalent and shared EGFR mutations that provide an ideal source for public neoantigens (NeoAg). Studies in both humans and animal models have confirmed the immunogenicity of some of these NeoAg peptides, suggesting that they may constitute viable targets for cancer immunotherapies. Peptide …

Message From The President, Georgia Southern University

Messages from the President

Dear Colleagues

Distinct Basal Ganglia Contributions To Learning From Implicit And Explicit Value Signals In Perceptual Decision-Making, Tarryn Balsdon, M. Andrea Pisauro, Marios G. Philiastides

School of Psychology

No abstract provided.

On Achieving Acceptable Levels Of Safety Risk In A Reinforcement Learning Environment, Christian Davila

McKelvey School of Engineering Graduate Student Theses & Dissertations

It is well-known that model correctness does not ensure the safe operation of systems that perform safety-critical functions. However, to ensure that potential hazardous events cannot occur, the model must be verified against its safety requirements, many derived during a systematic safety analysis. Typically, this process utilizes a complementary approach of formal verification and testing during the development process of complex systems. As these complex systems expand with the use of Reinforcement Learning (RL), safety considerations must be taken in the development of this technology. Although RL is becoming widely used across different industries, RL does pose some safety challenges. …

Strategies For Strengthening The Resilience Of Public Health Systems For Pandemics, Disasters, And Other Emergencies, Benjamin Ryan, Mayumi Kako, Rok Fink, Perihan Şimşek, Paul Barach, Jose Acosta, Sanjaya Bhatia, Mark Brickhouse, Matthew Fendt, Alicia Fontenot, Nahuel Arenas Garcia, Shelby Garner, Abdülkadir Gunduz, D Mike Hardin, Tim Hatch, Lashonda Malrey-Horne, Makiko Macdermot, Ryoma Kayano, Joshua Mckone, Chaverle Noel, Shuhei Nomura, Jeremy Novak, Andrew Stricklin, Raymond Swienton, Ismail Tayfur, Bryan Brooks

College of Population Health Faculty Papers

OBJECTIVE: The aim of this study was to identify and prioritize strategies for strengthening public health system resilience for pandemics, disasters, and other emergencies using a scorecard approach.

METHODS: The United Nations Public Health System Resilience Scorecard (Scorecard) was applied across 5 workshops in Slovenia, Turkey, and the United States of America. The workshops focused on participants reviewing and discussing 23 questions/indicators. A Likert type scale was used for scoring with zero being the lowest and 5 the highest. The workshop scores were analyzed and discussed by participants to prioritize areas of need and develop resilience strategies. Data from all …

Comparison Of A Bottom-Up Gnss Radio Occultation Method To Measure D- And E-Region Electron Densities With Ionosondes And Firi, Dylan J. Shaver, Dong L. Wu, Nimalan Swarnalingam, Anthony L. Franz, Eugene V. Dao, Daniel J. Emmons

Faculty Publications

High-frequency skywave propagation can be heavily impacted by D- and E-region dynamics requiring accurate global measurements to optimize performance. A standard measurement technique is to use ionosondes, but they are unable to measure below 1 MHz and are only available at a limited number of land-locked sites around the globe. In contrast, the Global Navigation Satellite System radio occultation (GNSS-RO) bottom-up method is a new approach specifically designed to generate electron density profiles in the D- and E- region ionosphere. It takes advantage of satellite constellations that currently provide over 20,000 daily measurements and global coverage. In this paper, GNSS-RO …

Ferromagnetic Resonators Synthesized By Metal-Organic Decomposition Epitaxy, Nhat Nguyen, Bryce Herrington, Kayetan Chorazewicz, Szu-Fan (Paul) Wang, Ruthi Zielinski, John Turner, Paul D. Ashby, Ufuk Kilic, Eva Schubert, Mathias Schubert, Ronald A. Parrott, Allen A. Sweet, Robert Streubel

Department of Physics and Astronomy: Faculty Publications

Metal-organic decomposition epitaxy is an economical wet-chemical approach suitable to synthesize high-quality low-spin-damping films for resonator and oscillator applications. This work reports the temperature dependence of ferromagnetic resonances and associated structural and magnetic quantities of yttrium iron garnet nanofilms that coincide with single-crystal values. Despite imperfections originating from wet-chemical deposition and spin coating, the quality factor for out-of-plane and in-plane resonances approaches 600 and 1000, respectively, at room temperature and 40 GHz. These values increase with temperature and are 100 times larger than those offered by commercial devices based on complementary metal-oxide semiconductor voltage-controlled oscillators at comparable production costs.

Tafopathies Result From Derangements In Transcriptional Regulation Of Metabolism, Jamison Maxwell Leid

Arts & Sciences Graduate Student Theses and Dissertations

Cardiogenesis and the maintenance of cardiac physiology necessitate dynamic and carefully coordinated transcription programs. Studies in a many systems – both in vitro and in vivo – have elucidated critical signaling pathways, including Bmp, Fgf, Wnt, and Notch that induce a cardiogenic transcription program, thereby driving cardiac specification and differentiation. Recently, studies have discovered additional regulation at the epigenetic level that contributes to the tight temporal and spatial control of cardiac gene expression during development. Because transcriptional regulation is essential to cardiogenesis, changes in transcriptional regulation result in developmental defects, including but not limited to CHDs, the leading inborn cause …