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A Short Communication On Exploring The Rearing, Breeding, And Future Outlook Of Damani Sheep In Pakistan, Muhammad Jamil, Ashiq Saleem, Abdul Razzaq, Naveed Ahmed, Muhammad Faraz Ahsan, Mujeeb Ur Rehman, Irem Anwar, Faiqah Ramzan, Zaheer Ahmad, Abdurehman Ameen Sep 2023

A Short Communication On Exploring The Rearing, Breeding, And Future Outlook Of Damani Sheep In Pakistan, Muhammad Jamil, Ashiq Saleem, Abdul Razzaq, Naveed Ahmed, Muhammad Faraz Ahsan, Mujeeb Ur Rehman, Irem Anwar, Faiqah Ramzan, Zaheer Ahmad, Abdurehman Ameen

Journal of Bioresource Management

The intentional production of animals is predicated on their genetic proficiency, which is dependent on optimal resource utilization and manipulation of biotic and abiotic environmental components to increase production for societal sustenance. The annual global consumption of sheep meat is approximately 2.5 kilograms per individual, out of a total of 41.6 kilograms. Three management systems are used to rear sheep: extensive wool and meat production, intensive milk production, and traditional pastoralism. Possessing adequate resources for sheep husbandry contributes to positive welfare outcomes. This review examined the rearing, breeding, and future potential of Damani sheep in Pakistan. Damani sheep are a …


Influence Of Municipal Solid Waste Dumpsite On Soil Physicochemical Properties And Vertical Distribution Of Heavy Metals, Chukwuebuka V. Azuka, Chikamso Ezeme Sep 2023

Influence Of Municipal Solid Waste Dumpsite On Soil Physicochemical Properties And Vertical Distribution Of Heavy Metals, Chukwuebuka V. Azuka, Chikamso Ezeme

Journal of Bioresource Management

The management of municipal solid waste (MSW) through open dumping or open burning has been a very common practice in Nigeria. The work investigated the impact of these practices on soil physicochemical properties and the vertical distribution of heavy metals at two dumpsites at Obollo-Afor and Nsukka in Southeastern Nigeria. Soil samples were collected at 10 m apart at depths of 0-20, 20-40, 40-60 cm from the dumpsite and at 100 m away from the dumpsite for the determination of soil physicochemical properties. A profile pit was dug at the center of each dumpsite while soil sample collection was done …


Best Management Practices And Standards, Training, And Tools To Increase Resilience Of The Edwards Aquifer Water Supply During Emergency Fire Control, Institute For Water Resources Science And Technology, Walter Den Sep 2023

Best Management Practices And Standards, Training, And Tools To Increase Resilience Of The Edwards Aquifer Water Supply During Emergency Fire Control, Institute For Water Resources Science And Technology, Walter Den

Water Resources Science and Technology Book and E-Book Publications and Reports (Archived)

In 2019 the Institute for Water Resources Science and Technology at Texas A&M University-San Antonio began work funded by the Proposition 1 Edwards Aquifer Protection Venue Project to develop Best Management Practices (BMPs) for protecting Edwards Aquifer water supplies from inadvertent contamination by HAZMAT in water runoff during emergency response-related firefighting. Results of this work are now available for your use. Technical information is available for use in developing and updating emergency response planning documents (i.e., City of San Antonio Hazard Mitigation Action Plan and the Bexar County Emergency Management Plan), educational curricula can be used for training and public …


A Case For Humanistic Theory, Salmoli Choudhuri, Moiz Tundawala Sep 2023

A Case For Humanistic Theory, Salmoli Choudhuri, Moiz Tundawala

Articles

This article responds to a debate in Economic & Political Weekly on the state of theory in Indian academia. While earlier interventions focused on the “who” and “how” questions related to the subject and work of theory, a more fundamental question is addressed here: Why theory at all? In our age of permanent crises, the necessity to make a case for theory that can interpret the world rather than change it for the good has arisen due to the dominance of problem-solving and solution-driven approaches adopted by the social sciences.


An Overlapped Sub-Array Hybrid Beamforming Architecture With Successive Interference Cancellation And Water-Filling In Massive Mimo Systems, Godwin Mruma Gadiel Sep 2023

An Overlapped Sub-Array Hybrid Beamforming Architecture With Successive Interference Cancellation And Water-Filling In Massive Mimo Systems, Godwin Mruma Gadiel

Tanzania Journal of Science

Over the years, wireless communication has significantly improved the data rate of mobile users. The key drive behind this success is the technological advancement in wireless communication. In the physical layer, hybrid beamforming has revolutionized the way signal reaches the user by constructively adding the signal at the destination thus improving the performance. Many researchers works have proposed different algorithms to solve for optimal hybrid beamforming. However, there is no single algorithm that can achieve both high spectral efficiency and energy efficiency at the same time. This work proposes a hybrid algorithm that combines successive interference cancellation and water filling …


Optical Characterization Of Photocatalytic Tungsten Oxide/Tin Oxide (〖Wo〗_3/〖Sno〗_2) Thin Films For Use In Degradation Of Water Pollutants, Victor Isahi, Christopher Maghanga, Mghendi Mwamburi, Onesmus Munyati, Sylvester Hatwaambo, Emmanuel Akoto, Wycliffe Isoe, Mir Waqas Alam Sep 2023

Optical Characterization Of Photocatalytic Tungsten Oxide/Tin Oxide (〖Wo〗_3/〖Sno〗_2) Thin Films For Use In Degradation Of Water Pollutants, Victor Isahi, Christopher Maghanga, Mghendi Mwamburi, Onesmus Munyati, Sylvester Hatwaambo, Emmanuel Akoto, Wycliffe Isoe, Mir Waqas Alam

Tanzania Journal of Science

Organic pollutants in water have been a challenge and pose significant risks to human health. As a result, research efforts to eliminate these pollutants have been on the rise. Photocatalysis has shown incredible potential in water treatment containing organic pollutants since it is affordable and utilizes solar energy. Tin oxide ( ) has ardently been investigated as a photocatalyst for water treatment due to its remarkable properties such as; non-toxicity, and stability. However, its wide band gap and the tendency for some electrons and holes to recombine during its use have been cited to be among limiting factors affecting its …


Effective Enhancement Of Post-Harvest Tomato Storage Through Wrapping Using Deacetylated Chitin Nanofibril-Plasticized Honey Films, Ngesa Ezekiel Mushi, Edina Meela, Divina Kaombe Sep 2023

Effective Enhancement Of Post-Harvest Tomato Storage Through Wrapping Using Deacetylated Chitin Nanofibril-Plasticized Honey Films, Ngesa Ezekiel Mushi, Edina Meela, Divina Kaombe

Tanzania Journal of Science

As one of the most grown seasonal fruit, tomato is widely consumed for making food products, drugs and ornaments. However, poor post-harvest handling system, transport and storage facilities deteriorate the quality of tomato fruits resulting into post-harvest losses. These problems have been addressed by the use of nanotechnology in this study. The combination of a chitosan surface and the core shell chitin results into novel deacetylated chitin nanofibril (DeChNF) with good biological activity and mechanical strength. The effectiveness of the DeChNF films for food preservation as an alternative material to chitosan is investigated. The DeChNF with degree of acetylation (DA) …


Hydro-Geochemistry And Related Processes Controlling The Composition Of Thermal Waters In The Lake Natron Basin, Northern Tanzania, Edista A. Abdallah, Charles H. Kasanzu, Crispin P. Kinabo, Akira Imai Sep 2023

Hydro-Geochemistry And Related Processes Controlling The Composition Of Thermal Waters In The Lake Natron Basin, Northern Tanzania, Edista A. Abdallah, Charles H. Kasanzu, Crispin P. Kinabo, Akira Imai

Tanzania Journal of Science

Lake Natron Basin (LNB) forms part of the eastern branch of the East African Rift System (EARS) in Tanzania. The basin is endowed with thermal springs flowing towards the lake from the western, northwestern, southwestern and eastern parts. The western, northwestern and south-western thermal springs emanate from fractures in the basaltic rocks while in the east, they originate from the western flank of the Gelai volcano. There are limited studies on these springs, thus their geochemical differences and distributions of physicochemical parameters are not well understood. A hydrogeochemical study was conducted to interpret available geochemical data from the LNB springs, …


Mineralogy And Geochemical Characteristics Of Matamba Kaolin Deposit-Njombe Region South-Western Tanzania: Implications For Industrial Applications, Melania A. Nyimbo, Ronald J. Massawe, Michael M. Msabi Sep 2023

Mineralogy And Geochemical Characteristics Of Matamba Kaolin Deposit-Njombe Region South-Western Tanzania: Implications For Industrial Applications, Melania A. Nyimbo, Ronald J. Massawe, Michael M. Msabi

Tanzania Journal of Science

Kaolin is a commercial clay material composed of hydrated aluminosilicate mineral kaolinite and used in various industrial applications such as ceramics, paper, paints, refractories, fiberglass, plastics, cosmetics and pharmaceuticals. It is formed as a result of strong chemical weathering of crystalline and feldspar-rich rocks or hydrothermal alteration of granitic rocks at relatively low temperature and pressure conditions. The kaolin deposit of Matamba originated from the weathering of leucogabbro rock during the development of the African land surface. In view of highlighted properties, the mineralogy and chemical characteristics of the Matamba kaolin deposit were investigated to determine its industrial applications. As …


Design Of A Cooling System Integrated With Ultraviolet Light For Preservation Of Fruits And Vegetables At Variable Tropical Weather Conditions: A Case Study Of Arusha, Tanzania, John Pyuza Gunda, Alexander Pogrebnoi, Baraka Kichonge Sep 2023

Design Of A Cooling System Integrated With Ultraviolet Light For Preservation Of Fruits And Vegetables At Variable Tropical Weather Conditions: A Case Study Of Arusha, Tanzania, John Pyuza Gunda, Alexander Pogrebnoi, Baraka Kichonge

Tanzania Journal of Science

Post-harvest losses of fruits and vegetables pose significant challenges, especially in tropical climates. This study introduces the development and performance evaluation of a solar-powered evaporative cooling storage system integrated with ultraviolet light (UV) designed for preservation of perishable fruits and vegetables. The cooling chamber supplied with ultraviolet lamp was developed using locally available materials such as sisal, sponge, and bricks. The performance of the system was evaluated in terms of air temperature decrease, relative humidity increase, and evaporative cooling power capacity both for sunny and cloudy tropical weather conditions. The study reveals that activating the UV light considerably extends the …


Wind Speed Forecasting Using Wavelet Analysis And Recurrent Artificial Neural Networks Based On Local Measurements In Singida Region, Tanzania, Rajabu J. Mangara, Mwingereza J. Kumwenda Sep 2023

Wind Speed Forecasting Using Wavelet Analysis And Recurrent Artificial Neural Networks Based On Local Measurements In Singida Region, Tanzania, Rajabu J. Mangara, Mwingereza J. Kumwenda

Tanzania Journal of Science

High accuracy wind speed forecasting is essential for wind energy harvest and plays a significant role in wind farm management and grid integration. Wind speed is intermittent in nature, which makes the forecasting to be a big challenge. In the present study, three hybrid single-step wind speed forecasting techniques are proposed and tested by local measurement data in Singida region, Tanzania. The three techniques are based on Wavelet Analysis (WA), Back Propagation (BP) optimization algorithm, and Recurrent Neural Network (RNN). They are referred to as WA-RNN, BP-RNN, and WA-BP-RNN. The model results showed that WA-BP-RNN outperforms the other two proposed …


Essential Workers Without Job Protection: Workers’ Power And The Impact Of The Covid-19 Pandemic On Indonesian Gig Workers, Arif Novianto, Anindya Dessi Wulansari, Yeremias T. Keban, Ari Hernawan Sep 2023

Essential Workers Without Job Protection: Workers’ Power And The Impact Of The Covid-19 Pandemic On Indonesian Gig Workers, Arif Novianto, Anindya Dessi Wulansari, Yeremias T. Keban, Ari Hernawan

Asia-Pacific Social Science Review

The impact of the COVID-19 pandemic has not only undermined global health but has also shaken the economy at large. Gig workers in the ride-hailing, goods delivery, and food delivery sectors, which are predicted as future jobs and categorized as essential jobs, are one of the jobs hardest hit by COVID-19. Gig work, currently characterized as piecework and without job security, where the workers depend on daily income, makes it one of the most vulnerable jobs. So when the COVID-19 pandemic occurred, their income decreased drastically, and the lack of job protection forced them to live in poverty. This article …


Experimental Measurements Of Ignition Delay Times Of Iso-Octane/N-Butanol Blend Mixtures In Rapid Compression Machine (Rcm), Myeji Materego, Derek Bradley Sep 2023

Experimental Measurements Of Ignition Delay Times Of Iso-Octane/N-Butanol Blend Mixtures In Rapid Compression Machine (Rcm), Myeji Materego, Derek Bradley

Tanzania Journal of Science

Among oxygenated alternative fuels, n-butanol is considered as a promising alternative biofuel which can partially (or fully) replace conventional transportation fuels currently in use. However, before n-butanol can be commercially utilised, its fundamental combustion characteristics need to be fully understood. In this work, the effect of adding n-butanol on autoignition property of iso-octane was studied. Measurements of ignition delay times for the two blends of n-butanol proportions of 30% and 50% by mole weight were made in a Rapid Compression Machine for stoichiometric mixtures at 2.0 MPa and temperature range 651-918 K. n-butanol increased ignition delay times of iso-octane at …


An Efficient Derivative Free Iterative Method And Condition Number Of Nonlinear Equations Arising From Real World Phenomena, Alatuhigha Nguni, Chacha S. Chacha, Adeline P. Mtunya Sep 2023

An Efficient Derivative Free Iterative Method And Condition Number Of Nonlinear Equations Arising From Real World Phenomena, Alatuhigha Nguni, Chacha S. Chacha, Adeline P. Mtunya

Tanzania Journal of Science

Recent researches have shown a great interest in developing novel numerical methods for solving nonlinear equations of the form  arising from real world phenomena.  However, very little attention has been given to the study of condition numbers which is an important aspect in measuring the sensitivity of the problem in response to slight perturbations in the input data. In this article, we present an efficient free derivative iterative scheme constructed by refining Newton-Raphson method standard form in which the derivative term is approximated by using finite difference scheme; hence making it derivative free. We also conducted an in-depth analysis of …


A Radial Basis Function Neural Network Algorithm For The Simultaneous Retrieval Of Two Meteorological Parameters From Solar Radiation, Nicholas W. Nzala, Nicolausi Ssebiyonga, Dennis Muyimbwa, Taddeo Ssenyonga Sep 2023

A Radial Basis Function Neural Network Algorithm For The Simultaneous Retrieval Of Two Meteorological Parameters From Solar Radiation, Nicholas W. Nzala, Nicolausi Ssebiyonga, Dennis Muyimbwa, Taddeo Ssenyonga

Tanzania Journal of Science

Local meteorological parameters are key in understanding the frequency of occurrence of extreme weather conditions such as floods, and droughts, among others. In this study, we present a method for simultaneous retrieval of two weather parameters. The method is based on already measured monthly average values of weather parameters from 2011 to 2016, which were used to train a Feed-forward radial basis function neural network (RBFNN) to obtain a fast and accurate method to compute global solar radiation for specified weather parameters pair. In inverse modelling, a multidimensional unconstrained non-linear optimization was employed to retrieve the weather parameters pair. The …


Evaluation Of The Inhibitive Properties Of Silver Nanoparticles In Senna Occidentalis Root Extract As Corrosion Inhibitor Of Mild Steel, Victor O. Egbeneje, Samuel E. Okhale, Chinyere Imoisi, Isaac O. Ogbogo, Omolade Ojo Sep 2023

Evaluation Of The Inhibitive Properties Of Silver Nanoparticles In Senna Occidentalis Root Extract As Corrosion Inhibitor Of Mild Steel, Victor O. Egbeneje, Samuel E. Okhale, Chinyere Imoisi, Isaac O. Ogbogo, Omolade Ojo

Tanzania Journal of Science

The use of nanoparticles as corrosion inhibitors has gained popularity because of its increased corrosion efficiency due to increase surface to volume ratio. Nanoparticles which undergo physisorption/chemisorption to the corrosion metal surface and inhibit the corrosion efficiently also have low toxicity, low cost and easy production. In this research work, weight lost method was applied to study the inhibitive properties of silver nanoparticles (AgNPs) synthesized using Senna occidentalis root extract as environmentally benign corrosion inhibitor of mild steel in 0.5 M H2SO4 medium at 298 K and 308 K. It was observed that the corrosion rate of the steel sample …


Enhancing Service Restoration In Tanzanian Power Grid Using Internet Of Things Sensors And Renewable Energy Sources, Rukia J. Mwifunyi, Daudi C. Mnyanghwalo, Shamte J. Kawambwa Sep 2023

Enhancing Service Restoration In Tanzanian Power Grid Using Internet Of Things Sensors And Renewable Energy Sources, Rukia J. Mwifunyi, Daudi C. Mnyanghwalo, Shamte J. Kawambwa

Tanzania Journal of Science

The increased dependence on the electric power grid, coupled with the increasing number of new customers, motivates the need to improve the reliability and resilience of the electric distribution systems. Modern distribution systems are becoming more resilient against power outages due to the increasing integration of Distributed Energy Resources (DERs) and the availability of efficient mechanisms for load shedding. Several studies considered fault detection and Service Restoration (SR) as separate problems without considering the implementation feasibility of integrating both solutions. To ensure the resiliency in the power system, it is important to have proper mechanisms which integrate sensing, detection, and …


New Education Policy 2020 And Online Education, Shaveta Arora Sep 2023

New Education Policy 2020 And Online Education, Shaveta Arora

Library Philosophy and Practice (e-journal)

In India's education system, the National Education Policy (NEP) 2020 offered a number of key reforms. The NEP-2020 initiatives at the heart of online education are the subject of the current study. The article explains how the strategy promotes the creation and distribution of excellent digital material for primary secondary and postsecondary education.


Updates On The Immune Cell Basis Of Hepatic Ischemia-Reperfusion Injury, Kang Ho Kim Sep 2023

Updates On The Immune Cell Basis Of Hepatic Ischemia-Reperfusion Injury, Kang Ho Kim

Faculty, Staff and Student Publications

Liver ischemia-reperfusion injury (IRI) is the main cause of organ dysfunction and failure after liver surgeries including organ transplantation. The mechanism of liver IRI is complex and numerous signals are involved but cellular metabolic disturbances, oxidative stress, and inflammation are considered the major contributors to liver IRI. In addition, the activation of inflammatory signals exacerbates liver IRI by recruiting macrophages, dendritic cells, and neutrophils, and activating NK cells, NKT cells, and cytotoxic T cells. Technological advances enable us to understand the role of specific immune cells during liver IRI. Accordingly, therapeutic strategies to prevent or treat liver IRI have been …


Microrna-145 Replacement As A Therapeutic Tool To Improve Trail Therapy, Sheema Khan, Saini Setua, Nirnoy Dan, Melida Flores Cantu, Ana Martinez Bulnes, Murali M. Yallapu, Stephen W. Behrman, Meena Jaggi, Subhash C. Chauhan, Sheema Khan Sep 2023

Microrna-145 Replacement As A Therapeutic Tool To Improve Trail Therapy, Sheema Khan, Saini Setua, Nirnoy Dan, Melida Flores Cantu, Ana Martinez Bulnes, Murali M. Yallapu, Stephen W. Behrman, Meena Jaggi, Subhash C. Chauhan, Sheema Khan

Research Symposium

Pancreatic cancer (PanCa) is a third leading cause of cancer related deaths in US. Unlike other cancers, PanCa is highly resistant to TNF-related apoptosis-inducing ligand (TRAIL) that emerges as one of the most-promising therapy in clinical trials. Our group has previously identified microRNA-145 (miR-145) is downregulated in PanCa, the restoration of which inhibits tumor growth and enhances gemcitabine sensitivity. In this study, we have observed that miR-145 restoration in PanCa cells renders them sensitive to TRAIL treatment. Therefore, we have engineered unique superparamagnetic nanoparticles (SPs) for co-delivering miR-145 and TRAIL in PanCa for improving their therapeutic response to TRAIL. The …


Engineering Of Functionalized Carbon Nano-Onions Embedded Bsa Nanocomposite Fibers For Stimuli-Responsive Drug Release, Ramiro Manuel Velasco Delgadillo, Narsimha Mamidi Sep 2023

Engineering Of Functionalized Carbon Nano-Onions Embedded Bsa Nanocomposite Fibers For Stimuli-Responsive Drug Release, Ramiro Manuel Velasco Delgadillo, Narsimha Mamidi

Research Symposium

Background: Advanced drug delivery systems (DDSs) have received enormous attention in biomedical applications due to their pharmacodynamic and pharmacokinetic drug properties. For the present study, poly 4-hydroxyphenyl methacrylate (PHPMA)/CNOs (f-CNOs) inserted bovine serum albumin (BSA) nanofibers were prepared for stimuli-responsive release of Doxorubicin (DOX). Temperature and pH would be altered to study the release of DOX in acidic microenvironments.

Methods: PHPMA were coupled with COOH-CNOs via ester coupling via the sonochemical method to produce PHPMA-CNOs (f-CNOs). Then, f-CNOs/DOX embedded BSA nanofibers were prepared at room temperature using Forcespinning. UV spectra of DOX-loaded nanofibers were studied to investigate the …


Engineered Exosomes For The Multimodal Imaging Directed Photo-Immunotherapy Of Colorectal Cancer, Deepak S. Chauhan, Meena Jaggi, Subhash C. Chauhan, Murali M. Yallapu Sep 2023

Engineered Exosomes For The Multimodal Imaging Directed Photo-Immunotherapy Of Colorectal Cancer, Deepak S. Chauhan, Meena Jaggi, Subhash C. Chauhan, Murali M. Yallapu

Research Symposium

Background: Rio Grande Valley experience severe cancer health disparity. A novel therapeutic modality may serve as better therapeutic option. Nanohybrids endowed with multifunctionality, longer circulation time, large surface area have emerged as an active preference for cancer research. However, rising concern of nanomaterials toxicity and scalability issues has slowed their translation to clinics. Exosomes (Exo) are endogenous endocytic origin 40-100 nm vesicles found in various body fluids, which in comparison to synthetic nanoparticles, are biodegradable, highly biocompatible as well as immunocompatible in nature. Although bulk isolation of exosomes from human body fluids is still a problem and engineering of exosomes …


Development Of A Novel Nir Fluorescent Probe For Breast Cancer Imaging, Neeraj Chauhan, Pallabita Chowdhury, Prashanth Kumar Bhusetty Nagesh, Elham Hatami, Nycol M. Cotto, Benilde Adriano, Meena Jaggi, Subhash C. Chauhan, Murali M. Yallapu Sep 2023

Development Of A Novel Nir Fluorescent Probe For Breast Cancer Imaging, Neeraj Chauhan, Pallabita Chowdhury, Prashanth Kumar Bhusetty Nagesh, Elham Hatami, Nycol M. Cotto, Benilde Adriano, Meena Jaggi, Subhash C. Chauhan, Murali M. Yallapu

Research Symposium

Background: Early-stage detection is crucial for successful breast cancer treatment and can significantly reduce breast cancer associated death rates. There are several diagnostic approaches available for early breast cancer diagnosis but lack tumor specificity and expose patients with radiation. Therefore, there is a crucial need to develop newer and safer imaging modalities. Indocyanine green (ICG), an FDA approved Near InfraRed (NIR) fluorescent probe-based imaging for early cancer detection and image guided surgery, has gained noticeable attention for the clinical applications as it has high sensitivity, low cost, and real-time visualization/imaging capabilities without ionizing radiation. However, ICG has several limitations associated …


Biocidal Properties Of Hybrid Nanonanomaterial, Chandrasekaran Karthikeyan, Kokkarachedu Varaprasad Sep 2023

Biocidal Properties Of Hybrid Nanonanomaterial, Chandrasekaran Karthikeyan, Kokkarachedu Varaprasad

Research Symposium

Background: Cancer is one of the essential unpredictable diseases worldwide; simultaneously, complicated issues created are by the human health system. Especially, breast cancer is the most commonly occurring cancer in women and is increasing remarkably in developing countries. It is a leading cause of cancer death in women, and breast cancer incidence rates are growing globally. To diagnose and treat cancer cells, different methods such as Radiation Therapy, Surgery, and Chemotherapy. These methods are high risk, more side effects, and high costs. The advanced healthcare material was developed to overcome this problem, inexpensive tools, and diagnosis of less-toxic drugs with …


Knowing The Unknowable: Visions Of Troubled Lands, Estella C. Kuchta Sep 2023

Knowing The Unknowable: Visions Of Troubled Lands, Estella C. Kuchta

Journal of Contemplative and Holistic Education

This paper describes the author’s clairvoyant visions of war and personal experiences of transrational knowledges. It is an account of one Westerner coming to know outside of and despite Western episteme. Transrational knowing was modelled by companion dogs in the author’s childhood and literary figures in early adulthood, and was experienced as a means of self-protection. Western culture fosters skepticism about transrational knowledges, such as psychic visions and telepathic connections. This paper asserts that transrational knowing—whether between humans, other species, or humans and other species—is a valid and readily available form of knowing that exists outside of and in spite …


Nuclear Powered International Commercial Shipping: A Note On The Greenest Solution And The Challenges Of International Regulation, Rebecca Mcreynolds Sep 2023

Nuclear Powered International Commercial Shipping: A Note On The Greenest Solution And The Challenges Of International Regulation, Rebecca Mcreynolds

Environmental and Earth Law Journal (EELJ)

To meet the environmental demands imposed by the International Maritime Organization, the commercial shipping industry’s use of predominantly marine diesel fuel will need to change drastically. Current answers to these environmental concerns include the use of biofuels, battery packs, and liquified natural gas, but these are short-term solutions that will not fully meet environmental demands in the long run. Nuclear propulsion, however, is a tried-and-true resolution. The use of nuclear energy results in virtually no environmental impact and has successfully been used by the US Navy for the past 75 years. Unfortunately, the commercial use of nuclear propulsion is stalled …


Reversing Quiet Destruction: Florida's Attempt To Regulate Pfas Known As Forever Chemicals, A. Colleen Donald Sep 2023

Reversing Quiet Destruction: Florida's Attempt To Regulate Pfas Known As Forever Chemicals, A. Colleen Donald

Environmental and Earth Law Journal (EELJ)

Introduced by manufacturing companies in the 1940s, Per-and polyfluorinated substances (“PFAS”) which consist of a group of over 6,000 chemicals, have insidiously made their way into the bloodstream of humans and into the environment. These nearly indestructible, “forever chemicals” that were once thought to be safe for use in firefighting foams, cosmetics, food packaging, non-stick cookware, and water-resistant clothing, are now found to be toxic. PFAS have been found in animals, aquatic life, and natural resources, and are associated with illnesses in humans: PFAS have been linked to various cancers, reproductive issues in women, and birth defects in children. As …


A 3d Printed Microneedle System For Transdermal Drug Delivery Of Anticancer Drugs, Md Jasim Uddin, Tanvir Ahmed, Dennis Douroumis Sep 2023

A 3d Printed Microneedle System For Transdermal Drug Delivery Of Anticancer Drugs, Md Jasim Uddin, Tanvir Ahmed, Dennis Douroumis

Research Symposium

Background: Transdermal delivery of drugs is an attractive alternative to the conventional route of administration as oral delivery. The hypodermic injections are painful and less patient compliance. Microneedles (MNs) are micron-sized, minimally invasive needles to deliver a wide range of molecules (e.g., small, DNA, vaccines etc.) to the upper portion of the dermis in a sustained and controlled manner, without causing any pain. The introduction of 3D printing technologies in the fabrication of MN will promote one-step manufacturing tools and scale-up for the delivery devices of anticancer drugs.

Methods: The 3D printed MN (3DMN) arrays were fabricated using Stereolithography (SLA), …


Mortaparibplus- A Novel Anticancer Small Molecule Abrogating Mortalin-P53 Interaction In Cancer Cells, Anissa N. Sari, Ahmed Elwakeel, Jaspreet K. Dhanjal, Vipul Kumar, Durai Sundar, Sunil C. Kaul, Renu Wadhwa Sep 2023

Mortaparibplus- A Novel Anticancer Small Molecule Abrogating Mortalin-P53 Interaction In Cancer Cells, Anissa N. Sari, Ahmed Elwakeel, Jaspreet K. Dhanjal, Vipul Kumar, Durai Sundar, Sunil C. Kaul, Renu Wadhwa

Research Symposium

Background. The cessation of tumor cell growth through cell cycle arrest and apoptosis is determined by p53, a tumor suppressor protein. However, the interaction between mortalin-p53 within cytoplasm/nucleus leads to the inactivation of p53 transcriptional activation function. The disruption of mortalin-p53 complex has been suggested as an approach for developing a potential anticancer drug.

Methods. A screening of a high-content chemical library was performed to determine a molecule with mortalin-p53-interaction disrupting characteristics. After four-rounds of visual assays, we discovered a triazole derivative (4-[(1E)-2-(2-phenylindol-3-yl)-1-azavinyl]-1,2,4-triazole, named MortaparibPlus) with a potential ability of disrupting mortalin-p53-complex. In this study, we recruited …


K-Distinct Lattice Paths, Eric J. Yager, Marcus Engstrom Sep 2023

K-Distinct Lattice Paths, Eric J. Yager, Marcus Engstrom

Rose-Hulman Undergraduate Mathematics Journal

Lattice paths can be used to model scheduling and routing problems, and, therefore, identifying maximum sets of k-distinct paths is of general interest. We extend the work previously done by Gillman et. al. to determine the order of a maximum set of k-distinct lattice paths. In particular, we disprove a conjecture by Gillman that a greedy algorithm gives this maximum order and also refine an upper bound given by Brewer et. al. We illustrate that brute force is an inefficient method to determine the maximum order, as it has time complexity O(nk).