Digital Commons Network^™

Biodegradable Pcl–Plga Electrospun Nanofibers For Localized Cancer Therapy, Rahul Tiwari, Pranav, Joel Delossantos, Eswara N.H.K. Ghali, Luis Chavez, Vishal Sharad Chaudhari, Songyang Han, Subhash Chauhan, Murali Yallapu

School of Medicine Publications

Localized chemotherapy offers a promising strategy to improve therapeutic efficacy while minimizing the systemic toxicity of conventional cancer treatment, particularly following tumor resection. Electrospun nanofibers are well suited for this purpose due to their high porosity, extracellular matrix-mimicking architecture, and capacity for localized drug release. In this study, electrospun nanofibers based on PCL and PLGA were developed for localized cancer therapy. Three distinct nanofibrous architectures were fabricated: PCL nanofibers, PCL−PLGA blended nanofibers, and PCL−PLGA multilayered (tetra-layered) nanofibers, and their encapsulation efficiency was determined by high-performance liquid chromatography (HPLC). Scanning electron microscopy confirmed uniform, bead-free nanofibrous morphologies, while Fourier transform infrared …

Gci-312 — Adaptive Agricultural Microclimate Conditioning System For Arid Environments, Michael Victor Caldwell Mr.

Defensive Publications Series

GCI‑312 is an open‑source, prototype‑ready adaptive agricultural microclimate conditioning system integrating electrostatic‑assisted droplet deposition, vortex atomization, pulsed evaporative cooling, environmental telemetry, and root‑zone thermal stabilization to experimentally reduce convective moisture loss and crop heat stress in arid environments. This disclosure provides full build and test specifications so a reader can assemble a 10×10 ft test cell and begin staged experiments immediately. The project targets substantial irrigation demand reductions under arid heat‑stress conditions (experimental targets: 20–30% irrigation reduction; exploratory upper target if all subsystems validate: up to 30–50% reduction) and documents clear hypotheses, test metrics, kill criteria, pivot paths, energy accounting, …

Paired-Satellite Coordinated Laser Ablation For Torque-Cancelled Deorbit Of Uncontrolled Orbital Debris, Daniel Austin Harbison

Defensive Publications Series

A method is disclosed for active orbital debris removal in which two satellites operate in coordinated formation on opposite sides of a target debris object and direct continuous-wave or pulsed laser ablation beams onto opposing faces of the target. The bilateral geometry provides three simultaneous effects: (1) surface ablation gradually weakens the structural integrity of degraded fasteners, adhesives, and thermal blankets on the debris exterior; (2) symmetric ablation plumes produce opposing reaction-torque components that cancel each other, suppressing the spin-up that would otherwise destabilize a single-beam ablation push; and (3) the combined photon pressure and plume-thrust components add as decelerating …

Magneto-Taurus-Energy, Alexander C. Roszko

Defensive Publications Series

TECHNICAL DISCLOSURE STATEMENT: PRIOR ART RECORD

TITLE OF INVENTION: The Magneto Taurus Energy Engine INVENTOR: Alexander Charles Roszko LEGAL STATUS: Open Source / Public Domain Hardware / Defensive Publication APPLICABLE PATENT EXAMINER SEARCH CLASS: Electric Propulsion; Mechanical Flywheel Energy Storage; Magnetic Levitation Assemblies.

I. BACKGROUND OF THE INVENTION The current industrial paradigm is deeply saturated with and reliant upon toxic petrochemical polymers, fluoropolymer coatings (PFAS), and non-biodegradable synthetic resins. Even inside modern manufacturing and digital fabrication toolsets, users are forced to utilize toxic photopolymer resins or cut plastics that generate dangerous airborne microplastics. Furthermore, conventional electromagnetic propulsion and power-generation systems …

Bilateral Beam-Assisted Rock Fracturing For Low-Gravity And Terrestrial Drilling Operations, Daniel Austin Harbison

Defensive Publications Series

A method is described for pre-fracturing rock using two or more counter-propagating millimeter-wave or microwave beams aimed at the same target volume from opposite sides. Standing-wave interference and overlapping absorption produce interior thermal-stress concentrations that initiate cracks at much lower bulk energy density than vaporization-based drilling, while the symmetric geometry largely cancels the net momentum imparted to the rock face. The architecture is intended primarily for low-gravity surface drilling on the Moon, Mars, and asteroids — where reaction-force budgets are extremely limited — and as a pre-conditioning step for terrestrial mechanical drills. The disclosure covers the baseline two-beam geometry at …

Modular Skid-Mounted Industrial Wastewater Pretreatment, Cavitation Conditioning, And Hazard Stream Isolation System For Variable-Feed Industrial Brines And Contaminated Process Water, Michael Victor Caldwell Mr.

Defensive Publications Series

This disclosure presents a modular skid-mounted industrial wastewater treatment system designed for variable and contaminated aqueous industrial streams. The system integrates staged flow equalization, hydrocyclone separation, hydrodynamic cavitation conditioning, electrochemical or precipitation-based treatment, and modular adsorption/ion exchange capture stages, followed by final polishing filtration. Outputs are separated into reusable water, concentrated recovery streams, and a stabilized hazardous residual stream for immobilization. The system is designed for pilot-scale evaluation under real industrial feed conditions with emphasis on fouling reduction, operational stability, and selective contaminant concentration performance.

Municipal Wet-Food Recovery & Supplemental Fertilizer Pellet System, Michael Victor Caldwell Mr.

Defensive Publications Series

This disclosure describes a simplified municipal waste-recovery system designed to:

• recover expired canned foods and wet household food waste,

• recycle steel and aluminum food containers,

• reduce landfill methane generation,

• reduce municipal landfill burden,

• and produce supplemental fertilizer pellets intended for blending with conventional agricultural fertilizers.

Unlike conventional composting systems requiring extensive sorting, this architecture intentionally focuses ONLY on:

• wet food waste,

• spoiled food,

• and canned food products.

The system uses:

• sealed household collection bins,

• dedicated sanitary pickup trucks,

• low-shear food recovery processing,

• metal separation,

• thermal sanitization,

• dewatering,

• and conventional pelletization equipment.

Automated Prompt Optimization For Large Language Model Training Data Synthesis, Hui Wu, Yulou Zhou, Rishabh Bhardwaj, Simon Zhao

Defensive Publications Series

The generation of high-fidelity synthetic training data for large language models is often constrained by a reliance on static, manually engineered prompts. A single optimized prompt typically fails to achieve high performance across an entire query distribution, leading to coverage gaps and reduced diversity in the resulting training trajectories. To address these limitations, an automated prompt optimization method is disclosed. An evolutionary process is employed to iteratively refine prompts by leveraging a meta-prompting mechanism that incorporates task-specific chain-of-thought guidelines. Rather than converging on a single global optimum, a set of high-performing prompts is identified. Candidate responses are generated for each …

Hukum Pengadaan Barang (Government Procurement) Dan Pembangunan Ekonomi, Ade Maman Suherman

Jurnal Hukum & Pembangunan

Abstract

Constitutional Question (Menyoal Konstltusjonalitas Pasal Tentang Pengemis Kuhp Pasal 504 Ayat (1) Dan (2)), Isrok Isrok

Jurnal Hukum & Pembangunan

Abstract

Catatan Singkat Mengenai Kedudukan Mpr Sesudah Perubahan Uud 1945, Fatmawati Fatmawati

Jurnal Hukum & Pembangunan

Abstract

Hak Asasi Manusia (Ham) Atas Lingkungan Hidup (Suatu Rekfleksi Sosio Yuridis Atas Implementasi Penyelesaian Sengketa Lingkungan), Junior B. Gregorius

Jurnal Hukum & Pembangunan

Abstract

To Purchase Or Not To Purchase: An Exploratory Investigation Of Electric/Battery Vehicle Attraction Versus Conventional Gasoline Powered Vehicles Among Potential African American Car Buyers As Moderated By The Individual’S Level Of Environmental Concern., George W. Stone

Atlantic Marketing Association Proceedings

No abstract provided.

Using Location Tracking And Gis Tools To Investigate Customers’ Cluster Shopping Behavior, Mark J. Sciuchetti Jr, Jianping Huang, Brent Cunningham

Atlantic Marketing Association Proceedings

No abstract provided.

Semiotic Analysis Of Consumer Generated Content Regarding The Fender Ultra Stratocaster, Rex Mcclure, Robert Boostrom

Atlantic Marketing Association Proceedings

No abstract provided.

Examination Of The Differences In Attitudes And Purchase Intentions By Forms Of Nostalgia, Montana Mcknight, Michael Levin

Atlantic Marketing Association Proceedings

No abstract provided.

Marketing For The Dreamwork Wrestling: How To Keep A Small Entrepreneurial Business And Dream Alive!, Steve Chen, Jennifer Mak, Karen Doran, Liz Allen

Atlantic Marketing Association Proceedings

No abstract provided.

Neuroscience-Based Intellectual Productivity: A Ten-Principle Methodology For Knowledge Workers, Yoshihiko Ariizumi

Learning, Teaching, & Researching Optimization

This paper presents a comprehensive, neuroscience-grounded methodology for enhancing intellectual productivity among knowledge workers—particularly academic faculty and researchers operating under conditions of chronic cognitive overload. Drawing on ten foundational principles derived from contemporary cognitive neuroscience, we argue that substantial gains in research output, creative ideation, and knowledge integration are achievable not by working harder, but by working in deliberate alignment with the brain’s native computational architecture.

The ten principles address: strategic activation of the Default Mode Network (DMN) for incubation and creative insight; prefrontal cortex (PFC) energy management through temporal task separation; externalization of cognitive load via AI-assisted working memory …

Working Smarter, Not Harder: A Practical Guide To Intellectual Productivity, Yoshihiko Ariizumi

Learning, Teaching, & Researching Optimization

This guide offers general suggestions drawn from recent research. Every person thinks, works, and recharges differently. Please treat what follows not as a checklist to follow slavishly, but as a menu of ideas — pick what resonates, adapt freely, and discard whatever does not fit your life.

Lt. Adam Peacock Reflects On 26 Years In Law Enforcement, Marisa C. Atkinson

University of Mississippi News

OXFORD, Miss. – Keeping the University of Mississippi and the country safe is what Lt. Adam Peacock has done for the past 26 years, but he is beginning a new chapter this spring. His last call with the University Police Department came on April 28.

181st University Of Notre Dame Commencement, University Of Notre Dame

Commencement Programs

• SCHEDULE OF EVENTS 4
• HEARING IMPAIRED INFORMATION 9
• GRADUATE SCHOOL 10
• MENDOZA COLLEGE OF BUSINESS GRADUATE BUSINESS 32
• GRADUATE ARCHITECTURE 38
• LAW SCHOOL 39
• UNIVERSITY COMMENCEMENT CEREMONY 42
• COLLEGE OF ARTS AND LETTERS 44
• COLLEGE OF SCIENCE 51
• COLLEGE OF ENGINEERING 55
• MENDOZA COLLEGE OF BUSINESS 61
• SCHOOL OF ARCHITECTURE 67
• KEOUGH SCHOOL OF GLOBAL AFFAIRS 67
• VALEDICTORIAN CANDIDATES 68
• EMERITI FACULTY 68
• HONOR SOCIETIES 69
• AWARDS AND PRIZES 77
• TASSELS 100

Guide For Brain Science-Based Ip Improvement, Yoshihiko Ariizumi

Learning, Teaching, & Researching Optimization

This guide leads to two articles that help you know the practical implications of the recent development of neuro-scientific discoveries.

Impact Of Food Insecurity On The Management Of Children With Food Allergy: A Scoping Review, Kiranjit Atwal, Kate Maslin

School of Nursing and Midwifery

Child health and development are affected by food insecurity, which is an increasing phenomenon globally. The rates of food allergy are also increasing, and the multifaceted burden is well documented. The higher costs of allergen-free food, essential to food allergy management, may compound the levels of food insecurity, but evidence is still emerging. This scoping review was conducted with the aim to understand the impact of food insecurity on the management of children living with food allergy by mapping the current types of evidence, key concepts, and research gaps. Following JBI methodology, evidence about children aged ≤18 years living in …

Influence Of Gas Atmosphere And Deposition Time On Si/Mno₂ Thin Films Properties Deposited By Magnetron Sputtering For Supercapacitor Application, Tansya Trisnatika Dewi, Boon Tong Goh, Reza Akbar Pahlevi, Ishmah Luthfiyah, Markus Diantoro

Journal of Mechanical Engineering Science and Technology (JMEST)

Thin films of MnO₂ were successfully deposited onto Si substrates using the magnetron sputtering technique in various gas atmospheres and deposition times to study their influence on the structural, morphological, electrical, and electrochemical properties for application as supercapacitor electrodes. Structural analysis using XRD showed that deposition under an Ar+O₂ gas atmosphere increased the crystallite size and crystallinity of the Si/MnO₂ films, while shorter deposition times reduced the crystallite size and lowered the crystallinity. Surface morphology observation using SEM showed that the film deposited in an Ar+O₂ gas atmosphere had smaller, more uniform, evenly distributed, and closely …

Influence Of Fiber Loading And Cu/Sio₂ Fillers On Mechanical And Physical Properties Of Sugarcane Bagasse Epoxy Composites, Ansor Salim Siregar, Indra Indra, Agung Fauzi Hanafi, Sunny Ineza Putri

Journal of Mechanical Engineering Science and Technology (JMEST)

The rising worldwide need for lightweight, high-strength, and eco-friendly materials has driven considerable investigation into natural fiber composites. This research offers an extensive examination of the creation and characterization of a new hybrid composite designed for high-performance sports equipment. The composite structure consists of an epoxy matrix strengthened with sugarcane bagasse fibers and synergistic blend of copper and silicon dioxide hybrid particulate fillers. Three unique composite variations were created, with systematically adjusted weight fractions of sugarcane bagasse fiber (35%, 31%, 27%) and hybrid fillers. A thorough assessment of mechanical and physical properties was carried out following ASTM standards. The results …

Is Panic Over E-Bike Safety Justified? A Review Of The Literature And Comparative Analysis With Conventional Bicycles And E-Scooters, Amir Ghanbari, Asha Weinstein Agrawal, Kevin Fang

Faculty Research, Scholarly, and Creative Activity

The increasing popularity of e-bikes has prompted global concerns about their safety. This literature review synthesizes English-language literature on e-bike safety, focusing on publication trends, data sources, major themes, and comparisons with human-powered bicycles and e-scooters. In total, 197 studies published between 2009 and June 2024 were reviewed. Research activity has expanded rapidly in recent years, with China and the United States emerging as the leading countries. Most studies examined rider demographics, crash involvement, rider behaviors, and comparisons with other traffic modes. The most common data sources were medical records, surveys, and naturalistic designs. Among studies comparing e-bike safety with …

Iron Age Ii Burials And Archaeological Investigations At Ḥorbat Menorim (El-Manara), Lower Galilee, Eliot Braun

'Atiqot

No abstract provided.

Old World Ranks On A New Frontier: Noncommissioned Officer Command In The United States Military, Robert K. Whillock

History Theses and Dissertations

This paper examines the development of the United States Noncommissioned Officer (NCO) Corps and the regulatory limits placed on its authority. The early American military adopted European traditions that reserved command for commissioned officers and confined NCOs to supervisory and disciplinary roles. Regulations reinforced this hierarchy by preventing NCOs from exercising autonomous command and limiting opportunities for advancement into the officer corps through merit. Over time, however, egalitarian reformers began to question whether these rigid distinctions served the needs of the evolving American military.

The paper argues that foreign military examples and operational necessity gradually challenged the established roles of …

Optical Nuclear Spin Detection In Diamond And Varifocal Metasurface Optics, Maxwell D. Aiello

Physics & Astronomy ETDs

This dissertation presents two experimental investigations at the intersection of quantum sensing and precision optical instrumentation. The primary project demonstrates optically detected nuclear magnetic resonance (NMR) of ¹³C nuclear spins in diamond, using state-selective Landau-Zener transitions under microwave frequency sweeping to bidirectionally transfer spin polarization between nitrogen-vacancy (NV) electron spins and remote ¹³C nuclear spins. This enables optical polarization and readout of large ensembles of polarized nuclear spins at low magnetic fields and room temperature, with spin dephasing times limited by longitudinal relaxation of nearby NV electron spins. The secondary project reports the design, fabrication, and characterization of …

The Environmental Cost Of Artificial Intelligence, Ava G. O'Connor

Student Theses 2015-Present

This paper addresses the increasingly innovative and evolving world of artificial intelligence. As artificial intelligence becomes more integrated within global economies and infrastructures, its  environmental and economic impact has grown significantly, but still remains understudied in the conversation surrounding societal advancement and growth. This thesis delves into the history and development of artificial intelligence, AI's integration into modern life, Big Tech jumping to get ahead of AI development through investment, the cost of artificial intelligence, and the ethical and environmental implications of increasing artificial intelligence usage. Using multiple case studies, this thesis deeply explores the emergence of artificial intelligence as …