Digital Commons Network^™

Kenyon Collegian - October 19, 2023

The Kenyon Collegian

No abstract provided.

The Minutes Of The Marshall University Staff Council Meeting, October 2023, Marshall University Staff Council

Staff Council Minutes

No abstract provided.

Bryant University Day Of Understanding, Equity In Action, Office Of Institutional Diversity, Equity, Inclusion, And Belonging

Day of Understanding Programs

No abstract provided.

Unh Researchers Investigate Climate Tolerant Buckwheat Crop For Future Commercial Use, Robbin Ray

Media Relations

No abstract provided.

Everybody, Otterbein Theatre And Dance Department

2023-2024 Season Productions

Everybody is a play written by Branden Jacobs-Jenkins. It is a modern adaptation of the 15th-century morality play Everyman, one of the first recorded plays in the English language. The play premiered Off-Broadway at the Irene Diamond Stage at Signature Theatre Company on February 21, 2017 with previews beginning January 31, 2017 and a closing date of March 19, 2017.[1] The play features the unique casting quirk of using a lottery system to define the roles of the play. Each actor must memorize the entire script and be prepared to play any role. This is meant to symbolize the randomness …

Shaq Tensley ’15, University Of Dayton

Blog: The Dayton Engineer

“Leave it better than you found it.” This motto has inspired Shaq Tensley ’15 to give back to UD as a volunteer, and it has served him in his global travels

Faculty Excellence 2023 Honors Outstanding Unh Educators, Keith Testa

UNH Today Archive

No abstract provided.

Water Beetles (Coleoptera) Associated With Afrotemperate Forest Patches In The Garden Route National Park, South Africa, Matthew S. Bird, David T. Bilton, Musa C. Mlambo, Renzo Perissinotto

School of Biological and Marine Sciences

Southern Afrotemperate Forest is concentrated in the southern Cape region of South Africa and whilst it is relatively well known botanically, the fauna, specifically the aquatic invertebrate fauna, is poorly documented. The majority of remaining intact forest habitat is contained within the Garden Route National Park (GRNP), which straddles the provincial boundary between the Western and Eastern Cape. This study undertakes a survey of the water beetle fauna inhabiting the GRNP. The aquatic ecosystems within temperate forests of the region are poorly researched from an ecological and biodiversity perspective, despite being known to harbour endemic invertebrate elements. We collected water …

Unraveling The Functional Dark Matter Through Global Metagenomics, Georgios A. Pavlopoulos, Fotis A. Baltoumas, Sirui Liu, Oguz Selvitopi, Antonio Pedro Camargo, Stephen Nayfach, Ariful Azad, Simon Roux, Lee Call, Natalia N. Ivanova, Min I. Chen, David Paez-Espino, Evangelos Karatzas, Nathan Ahlgren

Biology

Metagenomes encode an enormous diversity of proteins, reflecting a multiplicity of functions and activities^1,2. Exploration of this vast sequence space has been limited to a comparative analysis against reference microbial genomes and protein families derived from those genomes. Here, to examine the scale of yet untapped functional diversity beyond what is currently possible through the lens of reference genomes, we develop a computational approach to generate reference-free protein families from the sequence space in metagenomes. We analyse 26,931 metagenomes and identify 1.17 billion protein sequences longer than 35 amino acids with no similarity to any sequences from 102,491 …

Structural Design And Synthesis Of Growth Factor Receptor Binding Protein 2 (Grb2) Stabilizing Small Molecule, Mahfuzul Hasan

Theses and Dissertations

The growth factor receptor tyrosine kinase (RTK) family is a potent inducer of cellular growth. Ligand binding to cognate receptors on plasma membrane induces receptor dimerization and activation, which in turn recruits intracellular molecules for downstream signal transduction. A key signaling pathway activated by growth factor (GF) receptors is the Ras signaling cascade that ultimately leads to cell proliferation. Activation of RTKs leads to the recruitment of adapter protein Grb2, which is constitutively bound to the mammalian homolog of drosophila son of sevenless (SOS), and a guanine exchange factor (GEF) for Ras. The recruitment of the Grb2-SOS complex by activated …

From Corporate Career To Classroom Excellence, Aaron Sanborn

UNH Today Archive

No abstract provided.

2023 October 19-21, Faculty Senate Minutes, State University Of New York At Cortland

Minutes

Faculty Senate Minutes, 2023 October 19-21

New York State Fiscal Year 2025 Executive Budget Resolution

2023 October 19-21, Faculty Senate Minutes, State University Of New York At Cortland

Minutes

Faculty Senate Minutes, 2023 October 19-21

New York State Fiscal Year 2025 Executive Budget Resolution

First-Principles And Machine Learning Investigation Of Refractory High Entropy Alloys And Conventional Alloys., Uttam Bhandari

LSU Doctoral Dissertations

Refractory high entropy alloys (RHEAs) are gaining prominence because of their balanced mechanical properties and are regarded as suitable alloys for a variety of applications such as aerospace, structural material, nuclear, and hydrogen storage. The first part of the dissertation explored the mechanical and thermal properties of RHEAs, specifically HfNbTaTiZr and Hf_0.5Nb_0.5Ta_0.5Ti_1.5Zr, which have potential uses in the health industry. The first-principles method using 100 atom supercell was carried out to compute the lattice constant, density, elastic modulus, Poisson ratio, and Vickers hardness. These calculated results were consistent with the available experimental …

3-Dimensional Quartic Bézier Curve Approximation Model By Using Neutrosophic Approach, Siti Nur Idara Rosli, Mohammad Izat Emir Zulkifly

Neutrosophic Systems with Applications

In a 3-dimensional data collection process, there exists noise data that cannot be included to visualize the process. Therefore, it is difficult to deal with since fuzzy set and intuitionistic fuzzy set theories did not consider the indeterminacy problem. However, using a neutrosophic approach with three memberships: truth, false, and indeterminacy membership function, the error data will be treated as uncertain data by using the indeterminacy degree. Thus, this study will visualize the 3-dimensional quartic Bézier curve model by using neutrosophic set theory. To construct the model, the neutrosophic quartic control point must first be introduced to approximate the neutrosophic …

In Silico Prediction Of Sodium-Glucose Co-Transporter-2 (Sglt2) Inhibition Activity By Allium Fistulosum Compound Based On Skelspheres Molecular Descriptor, Rudy Heryanto, Aryo Tedjo, Dimas Noor

Indonesian Journal of Medical Chemistry and Bioinformatics

The Sodium-Glucose co-transporter-2 (SGLT2) inhibitor represents a novel agent for the treatment of type 2 diabetes. Drugs of this class function by inhibiting glucose reabsorption in the kidneys, thereby controlling blood glucose levels. It is known that SGLT2 inhibitors activate the AMPK signaling pathway by increasing the expression and activity of AMP-activated protein kinase (AMPK). In vivo tests have demonstrated that ethanolic and aqueous extracts of Welsh onion leaves (Allium fistulosum L) can reduce body weight, liver weight, adipocyte size, and enhance AMP-activated protein kinase (AMPK) expression. In this study, the inhibitory activity (IC50) of compounds within Allium fistulosum against …

Evaluation Of Equivalent Thermal Conductivity For Carbon Fiber-Reinforced Bentonite Through Experimental And Numerical Analysis, Yuan Feng, Jongwan Eun, Seunghee Kim, Yong-Rak Kim

Department of Civil and Environmental Engineering: Faculty Publications

Bentonite is widely used as a water-proof material in engineering, and fibers are added to reduce the crack development of bentonite after drying. Carbon fiber can reinforce bentonite in heat-sensitive projects because of its high thermal conductivity and potential inhibition of bentonite cracking. Thus, it is important to determine the thermal conductivity of carbon fiber-reinforced bentonite. This study evaluated the thermal conductivity of carbon fiber-reinforced bentonite by analytical solution, experiment, and finite element method (FEM) simulation and discussed the effects of carbon fiber content, fiber length, fiber distribution, and the porosity of bentonite on the thermal conductivity of reinforced bentonite. …

Editorial: Stem Cells And The Immune System., John M. Perry, Meng Zhao

Manuscripts, Articles, Book Chapters and Other Papers

No abstract provided.

Montana Kaimin, October 19, 2023, Students Of The University Of Montana, Missoula

Montana Kaimin, 1898-present

Student newspaper of the University of Montana, Missoula.

Road Maintenance Challenges: The Greatest Obstacle To Sustainable Development In South Sudan, Gai Chol Paul

Journal of Sustainable Social Impact

Road infrastructure plays a crucial role in the sustainable development of any nation. It connects communities, facilitates trade, and enables essential service delivery. However, road maintenance is one of the most significant challenges hindering sustainable development in South Sudan. The poor roads hinder economic growth, access to essential services, and social cohesion and are in dire need of repair and upkeep. Thus, I developed this qualitative multiple-case study to explore challenges that hinder road maintenance in South Sudan. I collected data through document review and semi-structured interviews with four road engineers, and then thematically analyzed the gathered data. Three themes …

An Observational Study To Assess Validity And Reliability Of Smartphone Sensor-Based Gait And Balance Assessments In Multiple Sclerosis: Floodlight Gaitlab Protocol, Mike D. Rinderknecht, Mattia Zanon, Tjitske A. Boonstra, Lorenza Angelini, Dimitar Stanev, Gabriela González Chan, Lisa Bunn, Frank Dondelinger, Richard Hosking, Jenny Freeman, Jeremy Hobart, Jonathan Marsden, Licinio Craveiro

School of Health Professions

Background Gait and balance impairments are often present in people with multiple sclerosis (PwMS) and have a significant impact on quality of life and independence. Gold-standard quantitative tools for assessing gait and balance such as motion capture systems and force plates usually require complex technical setups. Wearable sensors, including those integrated into smartphones, offer a more frequent, convenient, and minimally burdensome assessment of functional disability in a home environment. We developed a novel smartphone sensor-based application (Floodlight) that is being used in multiple research and clinical contexts, but a complete validation of this technology is still lacking. Methods This protocol …

Identifying Façade Orientations With Closely Similar Thermal Performance For Unifying Façade Design Features In Hot Arid Climate, Ahmed Sherif, Khaled Tarabieh, Islam Mashaly, Mariam Amer

Faculty Journal Articles

No abstract provided.

The Voices Of Physical Education Teachers: Its Pressure, Measure, And Treasure In Delivering Instruction In Physical Education, Carla Jobelle Culajara

Indonesian Journal of Research in Physical Education, Sport, and Health

The study shed light on addressing the challenges, coping strategies, and instructional approaches of Physical Education teachers. The study employed a qualitative research design using phenomenological, which was participated by 8 PE teachers working as secondary public school teachers in the Philippines. Purposive sampling was used to choose the participants to answer the study's objectives. To determine the results, coding and themes were utilized. There were four emerging themes based on the study's results: challenges in accessibility and availability, students’ interest, continuous personal and professional development, and differentiated teaching approaches. With the new normal of education, there were adjustments in …

Enhancing Rice Leaf Disease Classification: A Customized Convolutional Neural Network Approach, Ammar Kamal Abasi, Sharif Naser Makhadmeh, Osama Ahmad Alomari, Mohammad Tubishat, Husam Jasim Mohammed

All Works

In modern agriculture, correctly identifying rice leaf diseases is crucial for maintaining crop health and promoting sustainable food production. This study presents a detailed methodology to enhance the accuracy of rice leaf disease classification. We achieve this by employing a Convolutional Neural Network (CNN) model specifically designed for rice leaf images. The proposed method achieved an accuracy of 0.914 during the final epoch, demonstrating highly competitive performance compared to other models, with low loss and minimal overfitting. A comparison was conducted with Transfer Learning Inception-v3 and Transfer Learning EfficientNet-B2 models, and the proposed method showed superior accuracy and performance. With …

Adaptive Design Of Mrna-Loaded Extracellular Vesicles For Targeted Immunotherapy Of Cancer, Shiyan Dong, Xuan Liu, Ye Bi, Yifan Wang, Abin Antony, Kristin Huntoon, Yifan Ma, Xuefeng Li, Weiye Deng, Benjamin R Schrank, Adam J Grippin, Jonghoon Ha, Minjeong Kang, Mengyu Chang, Yarong Zhao, Rongze Sun, Xiangshi Sun, Jie Yang, Jiayi Chen, Sarah K Tang, L James Lee, Andrew S Lee, Lirong Teng, Shengnian Wang, Lesheng Teng, Betty Y S Kim, Zhaogang Yang, Wen Jiang

Faculty, Staff and Student Publications

The recent success of mRNA therapeutics against pathogenic infections has increased interest in their use for other human diseases including cancer. However, the precise delivery of the genetic cargo to cells and tissues of interest remains challenging. Here, we show an adaptive strategy that enables the docking of different targeting ligands onto the surface of mRNA-loaded small extracellular vesicles (sEVs). This is achieved by using a microfluidic electroporation approach in which a combination of nano- and milli-second pulses produces large amounts of IFN-γ mRNA-loaded sEVs with CD64 overexpressed on their surface. The CD64 molecule serves as an adaptor to dock …

Comparison Of Siren Social Needs Screening Tools And Simplified Omaha System Terms: Informing An Informatics Approach To Social Determinants Of Health Assessments, Jeana M Holt, Robin R Austin, Rivka Atadja, Marsha Cole, Theresa Noonan, Karen A Monsen

Faculty, Staff and Student Publications

Objective: Numerous studies indicate that the social determinants of health (SDOH), conditions in which people work, play, and learn, account for 30%-55% of health outcomes. Many healthcare and social service organizations seek ways to collect, integrate, and address the SDOH. Informatics solutions such as standardized nursing terminologies may facilitate such goals. In this study, we compared one standardized nursing terminology, the Omaha System, in its consumer-facing form, Simplified Omaha System Terms (SOST), to social needs screening tools identified by the Social Interventions Research and Evaluation Network (SIREN).

Materials and methods: Using standard mapping techniques, we mapped 286 items from 15 …

Acute Exposure To Two Biocides Causes Morphological And Molecular Changes In The Gill Ciliary Epithelium Of The Invasive Golden Mussel Limnoperna Fortunei (Dunker, 1857), Amanda Maria Siqueira Moreira, Erico Freitas, Mariana De Paula Reis, Júlia Meireles Nogueira, Newton Pimentel De Ulhôa Barbosa, André Luiz Martins Reis, Afonso Pelli, Paulo Ricardo Da Silva Camargo, Antonio Valadão Cardoso, Rayan Silva De Paula, Erika Cristina Jorge

Michigan Tech Publications

Limnoperna fortunei, the golden mussel, is a bivalve mollusk considered an invader in South America. This species is responsible for ecological and economic damages due to its voluminous fouling capability. Chemical biocides such as MXD-100™ and sodium dichloroisocyanurate (NaDCC) are often used to control L. fortunei infestations in hydraulic systems. Thus, we proposed to investigate the effects of different periods (24, 48 and 72 h) of exposure to MXD-100™ (0.56 mg L−1) and NaDCC (1.5 mg L−1) on the gills of L. fortunei through morphological and molecular analyses. NaDCC promoted progressive morphological changes during the analyzed periods and only an …

High-Dimensional Deconstruction Of Pancreatic Cancer Identifies Tumor Microenvironmental And Developmental Stemness Features That Predict Survival, Erik P Storrs, Prathamesh Chati, Abul Usmani, Ian Sloan, Bradley A Krasnick, Peter K Harris, Chloe M Sachs, Faridi Qaium, Chris Wetzel, S Peter Goedegebuure, Thomas Hollander, Hephzibah Anthony, Jennifer Ponce, Shahed Badiyan, Hyun Kim, David G Denardo, Gabriel D Lang, Natalie D Cosgrove, Vladimir M Kushnir, Dayna S Early, Kian-Huat Lim, William G Hawkins, Li Ding, Ryan C Fields, Koushik K Das, Aadel A Chaudhuri, Et Al.

2020-Current year OA Pubs

Numerous cell states are known to comprise the pancreatic ductal adenocarcinoma (PDAC) tumor microenvironment (TME). However, the developmental stemness and co-occurrence of these cell states remain poorly defined. Here, we performed single-cell RNA sequencing (scRNA-seq) on a cohort of treatment-naive PDAC time-of-diagnosis endoscopic ultrasound-guided fine needle biopsy (EUS-FNB) samples (n = 25). We then combined these samples with surgical resection (n = 6) and publicly available samples to increase statistical power (n = 80). Following annotation into 25 distinct cell states, cells were scored for developmental stemness, and a customized version of the Ecotyper tool was used to identify communities …

A Method For Establishing Card Relationships And System Thereof, Hunny Huria, Kira Blundell

Defensive Publications Series

The present disclosure relates to a technique for establishing a relationship between a plurality of payment cards held by the cardholder and further utilizing the established relationship to suggest alternative payment options, in case the first card is declined. The technique involves sending a query to a relationship manager (RM) by the merchant if the initiated transaction is declined to inquire whether it stores any established relationship between the cardholder’s multiple payment cards, communicated to it by the issuer entities. In response, the RM searches its database and deploys the learning model to suggest the best replacement option out of …

Use Of Mobile Applications For Information Management Among Library And Information Science Trainees In Federal Polytechnic Ede, Osun State, Nigeria, Blessing Babawale Amusan, Adepero Olajumoke Odumade Mrs.

Library Philosophy and Practice (e-journal)

The study is an assessment of the use of mobile applications for information management among year two National Diploma students in the Department of Library and Information Science, Federal Polytechnic Ede, Osun State, Nigeria. The study adopted a survey method and questionnaire were administered on the 164 students from which 152 were completed and returned. The study discovered that the students commonly used mobile applications for managing information relating to their academic activities and were highly skilled in using mobile applications for streaming videos, sharing of documents and uploading of information using social media apps, but majority. The study also …