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Articles 115621 - 115650 of 1114108
Full-Text Articles in Entire DC Network
Understanding The Tensions Of "Good Motherhood" Through Women's Digital Technology Use: Descriptive Qualitative Study, Danica Facca, Jodi Hall, Bradley Hiebert, Lorie Donelle Phd, Rn, Fcan
Understanding The Tensions Of "Good Motherhood" Through Women's Digital Technology Use: Descriptive Qualitative Study, Danica Facca, Jodi Hall, Bradley Hiebert, Lorie Donelle Phd, Rn, Fcan
Publications
BACKGROUND: Research suggests that expectant and new mothers consult and value information gathered from digital technologies, such as pregnancy-specific mobile apps and social media platforms, to support their transition to parenting. Notably, this transitional context can be rich with profound physiological, psychological, and emotional fluctuation for women as they cope with the demands of new parenting and navigate the cultural expectations of "good motherhood." Given the ways in which digital technologies can both support and hinder women's perceptions of their parenting abilities, understanding expectant and new mothers' experiences using digital technologies and the tensions that may arise from such use …
Robert Fitch Oral History, Robert Fitch, Lorenzo Spaccarelli
Robert Fitch Oral History, Robert Fitch, Lorenzo Spaccarelli
Raymond College
No abstract provided.
Gas Expansion Energy Of Coals With Different Metamorphic Degrees: Evolutionary Characteristics And Their Implications For The Outburst Prediction, Liu Gaofeng, Li Baolin, Zhang Zhen, Liu Huan, Guan Wenbo, Si Nian
Gas Expansion Energy Of Coals With Different Metamorphic Degrees: Evolutionary Characteristics And Their Implications For The Outburst Prediction, Liu Gaofeng, Li Baolin, Zhang Zhen, Liu Huan, Guan Wenbo, Si Nian
Coal Geology & Exploration
To achieve an elevated accuracy in the prediction of coal and gas outbursts, this study conducted mercury injection capillary pressure (MICP) tests and isotherm adsorption experiments on selected six coal samples with different metamorphic degrees. Furthermore, it calculated the gas expansion energy of coals and analyzed the evolutionary characteristics of the gas expansion energy of coals with different metamorphic degrees, as well as their relationships with the prediction indices of coal and gas outbursts. The results of this study are as follows: (1) The differences in the pore structures and adsorptivity of coals with different metamorphic degrees led to different …
Water-Blocking Performance Of Laterite In Weak Deposition Areas Of Neogene Baode Formation And Its Significance Of Resource Exploitation, Zeng Yifan, Bao Han, Wu Qiang, Meng Shihao, Hua Zhaolai, Miao Yanping, Zhang Ye, Bu Wenyang
Water-Blocking Performance Of Laterite In Weak Deposition Areas Of Neogene Baode Formation And Its Significance Of Resource Exploitation, Zeng Yifan, Bao Han, Wu Qiang, Meng Shihao, Hua Zhaolai, Miao Yanping, Zhang Ye, Bu Wenyang
Coal Geology & Exploration
The in-depth study on the water-blocking performance of laterite in the weak deposition areas of the key aquiclude is of significant importance for mine production safety and ecological water resource protection. Specifically, the borehole data were re-optimized based on the regional sedimentary characteristics, the thickness distribution pattern of laterite deposit in Yushen mining area was studied, and the micro-engineering characteristics and control factors related to the water-blocking performance of laterite were explored. The results show that the deposition thickness of laterite gradually increases from northwest to southeast, the distribution of laterite becomes extremely uneven with the evolution of rivers, and …
Prediction Of Rockburst Intensity Grade Based On Convolutional Neural Network, Li Kangnan, Wu Yaqin, Du Feng, Zhang Xiang, Wang Yiqiao
Prediction Of Rockburst Intensity Grade Based On Convolutional Neural Network, Li Kangnan, Wu Yaqin, Du Feng, Zhang Xiang, Wang Yiqiao
Coal Geology & Exploration
Rockburst is one of the urgent problems to be addressed in the process of deep resource extraction. In order to predict the rockburst disasters safely and efficiently, a rockburst intensity grade prediction model (MICE-CNN) based on the Multiple Imputation by Chained Equations (MICE) and Convolutional Neural Network (CNN) was proposed. Specifically, a predictive indicator system was established based on the main influencing factors and the acquisition conditions of rockburst. A total of 120 sets of raw data from rockburst cases were collected, with the outliers processed by pauta criterion. Then, the missing data were interpolated with the four interpolation models …
Status And Development Of Intelligent Drilling Tools For Coal Mine, Gao Xiaoliang
Status And Development Of Intelligent Drilling Tools For Coal Mine, Gao Xiaoliang
Coal Geology & Exploration
As an important part of intelligent drilling, the intelligence of drilling tool system plays a crucial role in the intelligent development of coal mine underground drilling. In order to deeply explore the development direction of intelligent drilling tools, the research results and technical characteristics of intelligent drilling tools in coal mines were systematically sorted out from the aspects of directional drilling tools, measurement while drilling (MWD) system, intelligent drilling pipes and drill bits with reference to the experience in development of oil and gas industry, and the existing shortcomings were also summarized. It is pointed out that screw motor is …
The Paradox Of Leadership Coaching In A Vuca World, Raymond L. Forbes
The Paradox Of Leadership Coaching In A Vuca World, Raymond L. Forbes
All Faculty and Staff Scholarship
What does it feel like to be living right in the middle of a major paradox? Disorienting? Confusing? Unbalancing? One of the definitions of a Paradox is a situation, person, or thing that combines contradictory features or qualities. For many organizational leaders today dealing with paradox has become a recurrent feature of executive life. The contradictory features may arise in the form of a choice between apparently diametrically opposed alternatives. In fact, in the worst case, the best available options might all be equally undesirable. This uncertainty over paradox seems to be reflective of the many quandaries confronted by leaders …
Senate Meeting, October, 25, 2023, Academic Senate
Senate Meeting, October, 25, 2023, Academic Senate
Academic Senate Minutes
No abstract provided.
Methods For Estimating Carbon Emissions From Coals In Underground Mines: A Case Study Of The Western Fukang Mining Area, Peng Rendong, Wei Bo, Li Xin, Zhang Ji, Zhang Zizhao, Wang Bo, Zhang Na, Cui Deguang
Methods For Estimating Carbon Emissions From Coals In Underground Mines: A Case Study Of The Western Fukang Mining Area, Peng Rendong, Wei Bo, Li Xin, Zhang Ji, Zhang Zizhao, Wang Bo, Zhang Na, Cui Deguang
Coal Geology & Exploration
Carbon emissions have come into sharp focus of human society. The carbon emissions from coals rank as the most predominant part of China’s total carbon emissions. Presently, there is no available study on the accurate calculation of carbon emissions from coals in typical underground mines in Xinjiang, with the CH4 emission even overlooked. This study centers on the carbon emissions from coals in underground mines in the western Fukang mining area. As per the occurrence laws of CH4 and CO2 in coal seams, as well as coal mining plans, this study classified the sources of carbon emissions …
A Method For Identifying Faults Within Mining Faces Based On Spatial Statistics, Feng Yajie, Wen Guangchao, Wu Bingjie, Hu Zudong
A Method For Identifying Faults Within Mining Faces Based On Spatial Statistics, Feng Yajie, Wen Guangchao, Wu Bingjie, Hu Zudong
Coal Geology & Exploration
Minor faults within mining faces of coal mines severely affect gas drainage and coal seam mining. Accurately identifying parameters such as positions, throws, and attitudes of these faults is of great significance for the safe production of coal mines. To effectively reduce gas emissions, prevent gas explosions, and exploit and utilize gas resources, many gas drainage holes have been drilled during the construction of coal mines, providing favorable engineering conditions for identifying minor faults within coal seams. Compared with the conventional fault identification methods, which rely on the expertise of geologists, the identification model based on mathematical statistics and space …
An Improved Automated Testing Model For Maceral Groups In Coals Based On Deeplabv3+, Hu Jinwei, Xi Zhenghao, Xu Guozhong, Li Zhongfeng, Liu Xiang
An Improved Automated Testing Model For Maceral Groups In Coals Based On Deeplabv3+, Hu Jinwei, Xi Zhenghao, Xu Guozhong, Li Zhongfeng, Liu Xiang
Coal Geology & Exploration
The identification of maceral groups in coals plays a critical role in analyzing the chemical properties of coals. However, manual identification is laborious and requires high expertise. Existing computer-assisted identification methods, mostly adopting deep learning-based semantic segmentation models, fail to accurately identify maceral groups in coals due to complex compositions of microscopic coal images and the presence of transitional components. Therefore, this study proposed an improved DeeplabV3+ semantic segmentation model integrating the Swin Transformer backbone network and the SkNet. First, to deal with the challenge of feature extraction caused by the intertwined maceral groups and the presence of transitional components …
Discovery And Generation Mechanisms Of Epigenetic Biogenic H2S From Coal Seams In The Fukang Block, Southern Junggar Basin, China, Yan Peipei, Su Xianbo, Zou Chenglong, Zhao Weizhong, Wang Lufei, Fu Haijiao
Discovery And Generation Mechanisms Of Epigenetic Biogenic H2S From Coal Seams In The Fukang Block, Southern Junggar Basin, China, Yan Peipei, Su Xianbo, Zou Chenglong, Zhao Weizhong, Wang Lufei, Fu Haijiao
Coal Geology & Exploration
In the Fukang block located in the eastern part of the southern Junggar Basin, coalbed methane (CBM) from CBM wells exhibits a gradually increasing H2S concentration in the process of CBM production via water drainage, severely threatening production safety. Based on the CBM exploration and extraction data, as well as the anaerobic fermentation experiments, this study preliminarily investigated the causes of abnormal H2S concentrations during the CBM production in the Fukang block. As indicated by the gas content test in the CBM exploration stage, the original CBM showed a low H2S concentration of only …
Pfc Numerical Analysis On Crack Initiation Mechanism Of Fracture Grouting In Top Of Ordovician Limestone, Liu Zhaoxing, Zhang Qi
Pfc Numerical Analysis On Crack Initiation Mechanism Of Fracture Grouting In Top Of Ordovician Limestone, Liu Zhaoxing, Zhang Qi
Coal Geology & Exploration
The advanced regional grouting is an effective means to prevent and control the water hazard of limestone in coal seam floor, and the fracture grouting projects is a key link to determine the effect of the grouting in floor against water hazard. However, due to the unclear understanding of the fracture initiation mechanism of the injected limestone stratum, the grouting pressure, grout water-cement ratio and other grouting parameters in the process of fracture grouting are not effectively controlled. Thus, it is difficult to guarantee the grouting effect. In order to solve the above problems, numerical simulation calculation was conducted for …
Water Inrush Mechanism Of Coal Mine Shaft Fracture Under Fluid-Solid Coupling, Xue Weipei, Shen Lei, Yao Zhishu, Cheng Hua, Rong Chuanxin
Water Inrush Mechanism Of Coal Mine Shaft Fracture Under Fluid-Solid Coupling, Xue Weipei, Shen Lei, Yao Zhishu, Cheng Hua, Rong Chuanxin
Coal Geology & Exploration
The occurrence of coal mine shaft fractures and water inrush accidents is alarmingly frequent, endangering the lives of underground personnel and compromising mine safety. To comprehend the influence of confined groundwater in the process of shaft fracture and the formation mechanism of water inrush channels, a model test was devised using similarity theory and coupled fluid-solid numerical simulation technology. The findings reveal that direct contact between the shaft lining and pressurized water hinders the development of load-bearing and deformation capacities. This is specifically evidenced by the premature appearance of the yield point, a reduction in peak strength and strain, and …
Zoned Prediction Of Water Inflow After Dewatering Of Working Face Based On Waterrichness Zoning Of Aquifer, Yang Lei, Lei Fangchao, Hou Enke, Lu Bo, Feng Dong, Zhao Kaixing
Zoned Prediction Of Water Inflow After Dewatering Of Working Face Based On Waterrichness Zoning Of Aquifer, Yang Lei, Lei Fangchao, Hou Enke, Lu Bo, Feng Dong, Zhao Kaixing
Coal Geology & Exploration
As the weathered bedrock and burned rock aquifers seriously threaten the production safety of mines in the Jurassic coalfield of northern Shaanxi Province, accurate prediction of their waterrichness and water inflow at the working face is of great significance for water control in mines. Aiming at the weathered bedrock and burned rock aquifers with close hydraulic connection, the area where working face 15217 of Shaanxi Hongliulin Coal Mine is located was taken as the study area. Meanwhile, the aquifer thickness, lithological combination index, index of rock burning and weathering degree and core recovery was taken as the evaluation indexes. The …
Numerical Model Of Two-Region Flow By Constant-Head Pumping In An Unconfined Aquifer, Shi Pengyu, Zong Yijie, Teng Kaiqing, Liu Jianjun, Xiao Liang
Numerical Model Of Two-Region Flow By Constant-Head Pumping In An Unconfined Aquifer, Shi Pengyu, Zong Yijie, Teng Kaiqing, Liu Jianjun, Xiao Liang
Coal Geology & Exploration
In order to reveal the mechanism of two-region Darcian and non-Darcian flow induced by constant-head pumping tests in unconfined aquifers, a numerical model of well flow by constant-head pumping underground based on finite difference solution was proposed. In the model, it is assumed that the aquifer is divided into two regions according to the pumping flow characteristics: the finite non-Darcian flow region near the pumping well and the semi-infinite Darcian flow region far away from the pumping well. Specifically, the flow regime in the non-Darcian flow region was simulated by the Izbash’s equation, and the reliability of the proposed solution …
Study On Mesoscopic Failure Characteristics Of Layered Red Shale, Ma Zhenqian, Zhou Lang, Zuo Yujun, Zhang Jimin, Zou Yihuai, Cao Yunqin
Study On Mesoscopic Failure Characteristics Of Layered Red Shale, Ma Zhenqian, Zhou Lang, Zuo Yujun, Zhang Jimin, Zou Yihuai, Cao Yunqin
Coal Geology & Exploration
To study the mesoscopic failure characteristics of the layered red shale, uniaxial mechanical experiments were carried out by applying DSTD-1000 electro-hydraulic servo rigid pressure on the red shale with different bedding angles. Meanwhile, SEM and XRD experiments were implemented on debris to obtain its mechanical parameters, failure characteristics, microstructure, and relative content of components. Based on this, models of the red shale with different bedding angles were constructed using the discrete element PFC3D for the uniaxial compression experiments to study the mesoscopic failure characteristics of red shale. The results show that: (1) When the bedding angle θ=30°, 45°, …
Numerical Simulations And Wavefield Analysis Of In-Seam Wave Advance Detection In Viscoelastic Media, He Dixiu, Ji Guangzhong, Jiao Wenjie, Zhang Yawei, Yu Kun
Numerical Simulations And Wavefield Analysis Of In-Seam Wave Advance Detection In Viscoelastic Media, He Dixiu, Ji Guangzhong, Jiao Wenjie, Zhang Yawei, Yu Kun
Coal Geology & Exploration
In-seam waves are commonly applied to the advance detection of hidden faults in front of mining faces. However, coal seams, which have viscoelasticity actually, imposing absorptive and attenuation effects on in-seam waves. To investigate the wave field characteristics and propagation patterns of in-seam waves in viscoelastic coal seam media, this study built a three-dimensional geological model of coal measures with faults based on Kelvin-Voigt’s first-order velocity-stress equation. Using this equation, three-dimensional finite-difference numerical simulation was carried out. The results indicate that (1) for reflected in-seam waves in viscoelastic media, which exhibit high energy attenuation, their propagation and attenuation characteristics are …
Manipulator Trajectory Planning Method Of Anchor Drilling Robot, Lei Mengyu, Zhang Xuhui, Yang Wenjuan, Dong Zheng, Wan Jicheng, Zhang Chao, Du Yuyang
Manipulator Trajectory Planning Method Of Anchor Drilling Robot, Lei Mengyu, Zhang Xuhui, Yang Wenjuan, Dong Zheng, Wan Jicheng, Zhang Chao, Du Yuyang
Coal Geology & Exploration
In order to improve the support efficiency of coal mine roadway and the automation intelligence of heading face, an anchor drilling robot integrating the cantilever roadheader and the six-degree-of-freedom manipulator was designed, and studied on the anchor drilling sequence planning strategy and the drilling boom trajectory planning method. Firstly, the kinematics model of the manipulator structure was established based on the improved DH method. On this basis, the forward and inverse kinematics solutions were analyzed, and the spatial position and the corresponding joint variable values of the drilling rig were calculated. Secondly, the manipulator space was analyzed based on Monte …
Evaluation Of Equivalent Thermal Conductivity For Carbon Fiber-Reinforced Bentonite Through Experimental And Numerical Analysis, Yuan Feng, Jongwan Eun, Seunghee Kim, Yong-Rak Kim
Evaluation Of Equivalent Thermal Conductivity For Carbon Fiber-Reinforced Bentonite Through Experimental And Numerical Analysis, Yuan Feng, Jongwan Eun, Seunghee Kim, Yong-Rak Kim
Department of Civil and Environmental Engineering: Faculty Publications
Bentonite is widely used as a water-proof material in engineering, and fibers are added to reduce the crack development of bentonite after drying. Carbon fiber can reinforce bentonite in heat-sensitive projects because of its high thermal conductivity and potential inhibition of bentonite cracking. Thus, it is important to determine the thermal conductivity of carbon fiber-reinforced bentonite. This study evaluated the thermal conductivity of carbon fiber-reinforced bentonite by analytical solution, experiment, and finite element method (FEM) simulation and discussed the effects of carbon fiber content, fiber length, fiber distribution, and the porosity of bentonite on the thermal conductivity of reinforced bentonite. …
A Neutrosophic Multi-Criteria Model For Evaluating Sustainable Soil Enhancement Methods And Their Cost Implications In Construction, Ahmed El-Douh, Songfeng Lu, Ahmed Abdelhafeez, Alber Aziz
A Neutrosophic Multi-Criteria Model For Evaluating Sustainable Soil Enhancement Methods And Their Cost Implications In Construction, Ahmed El-Douh, Songfeng Lu, Ahmed Abdelhafeez, Alber Aziz
Sustainable Machine Intelligence Journal
This paper provides a comprehensive overview of the application of life cycle assessment (LCA) to promote sustainable soil practices in construction foundation projects. The aim is to evaluate the environmental impact and long-term sustainability of soil-related activities in construction through the lens of LCA. This assessment encompasses a wide array of factors, including soil quality, erosion control, contaminant remediation, soil stability, conservation, drainage management, and compliance with regulatory standards. To address this multifaceted evaluation, we employ a multi-criteria decision-making (MCDM) model, specifically introducing the Multi-Attributive Border Approximation Area Comparison (MABAC) method. This MCDM technique is utilized to appraise the sustainability …
A Comparative Analysis Of Machine Learning Models For Prediction Of Chronic Kidney Disease, Nariman Khalil, Mohamed Elkholy, Mohamed Eassa
A Comparative Analysis Of Machine Learning Models For Prediction Of Chronic Kidney Disease, Nariman Khalil, Mohamed Elkholy, Mohamed Eassa
Sustainable Machine Intelligence Journal
Prediction of chronic kidney disease (CKD) has emerged as a useful technique for early detection of at-risk persons and the introduction of appropriate management strategies. Machine learning and data-driven methods have been used in predictive modeling to examine massive databases of patient demographics, medical histories, test findings, and genetic information. These cutting-edge methods allow for the profiling of high-risk patients and the tailoring of healthcare administration approaches. Patient outcomes, complication rates, and healthcare system efficiency may all benefit greatly from CKD screening and prediction. Responsible use of CKD prediction algorithms, however, requires resolving issues with data availability, integration, and ethics. …
Faculty Senate Minutes, Georgia Southern University, Faculty Senate
Faculty Senate Minutes, Georgia Southern University, Faculty Senate
Faculty Senate Minutes
No abstract provided.
Postsynthetic Modification Of The Nonanuclear Node In A Zirconium Metal−Organic Framework For Photocatalytic Oxidation Of Hydrocarbons, Rebecca Shu Hui Khoo, Christian Fiankor, Sizhuo Yang, Wenhui Hu, Chongqing Yang, Jingzhi Lu, Martha D. Morton, Xu Zhang, Yi Liu, Jier Huang, Jian Zhang
Postsynthetic Modification Of The Nonanuclear Node In A Zirconium Metal−Organic Framework For Photocatalytic Oxidation Of Hydrocarbons, Rebecca Shu Hui Khoo, Christian Fiankor, Sizhuo Yang, Wenhui Hu, Chongqing Yang, Jingzhi Lu, Martha D. Morton, Xu Zhang, Yi Liu, Jier Huang, Jian Zhang
Department of Chemistry: Faculty Publications
Heterogeneous catalysis plays an indispensable role in chemical production and energy conversion. Incorporation of transition metals into metal oxides and zeolites is a common strategy to fine-tune the activity and selectivity of the resulting solid catalysts, as either the active center or promotor. Studying the underlying mechanism is however challenging. Decorating the metal-oxo clusters with transition metals in metal−organic frameworks (MOFs) via postsynthetic modification offers a rational approach to construct well-defined structural models for better understanding of the reaction mechanism. Therefore, it is important to expand the materials scope beyond the currently widely studied zirconium MOFs consisting of Zr6 …
Diesel Tractor Fuel Efficiency And Exhaust Emissions Standards, Jerin Tekolste, Cory Walters, Michael Mccullough, Lynn Hamilton, Lia Nogueira, Roger M. Hoy
Diesel Tractor Fuel Efficiency And Exhaust Emissions Standards, Jerin Tekolste, Cory Walters, Michael Mccullough, Lynn Hamilton, Lia Nogueira, Roger M. Hoy
Cornhusker Economics
Diesel engine performance and costs represent crucial factors for agricultural producers while pollutants from the exhaust are largely a social concern but also important to producers. Beginning in 1970, Congress authorized the Environmental Protection Agency to regulate emissions with amendments in subsequent years (U.S. EPA, 2023). In 1996 the EPA issued strict Exhaust Emission Standards for Nonroad Compression-Ignition Engines, causing a major paradigm shift in acceptable emission levels. A primary concern coming from many manufacturers was the difficulty of designing an engine to meet these standards without compromising the engines’ power output and efficient fuel consumption (Lloyd and Cackette 2001; …
Integration And Dosimetric Validation Of A Dynamic Collimation System For Pencil Beam Scanning Proton Therapy, Alonso Gutiérrez
Integration And Dosimetric Validation Of A Dynamic Collimation System For Pencil Beam Scanning Proton Therapy, Alonso Gutiérrez
All Publications
Objective. To integrate a Dynamic Collimation System (DCS) into a pencil beam scanning (PBS) proton therapy system and validate its dosimetric impact. Approach. Uncollimated and collimated treatment fields were developed for clinically relevant targets using an in-house treatment plan optimizer and an experimentally validated Monte Carlo model of the DCS and IBA dedicated nozzle (DN) system. The dose reduction induced by the DCS was quantified by calculating the mean dose in 10- and 30-mm two-dimensional rinds surrounding the target. Aselect number of plans were then used to experimentally validate the mechanical integration of the DCS and beam scanning controller system …
Breakdown Of The Drift-Diffusion Model For Transverse Spin Transport In A Disordered Pt Film, Kirill D. Belashchenko, Giovanni G. Baez Flores, Wuzhang Fang, Alexey Kovalev, Mark Van Schilfgaarde, Paul M. Haney, Mark D. Stiles
Breakdown Of The Drift-Diffusion Model For Transverse Spin Transport In A Disordered Pt Film, Kirill D. Belashchenko, Giovanni G. Baez Flores, Wuzhang Fang, Alexey Kovalev, Mark Van Schilfgaarde, Paul M. Haney, Mark D. Stiles
Department of Physics and Astronomy: Faculty Publications
Spin-accumulation and spin-current profiles are calculated for a disordered Pt film subjected to an in-plane electric current within the nonequilibrium Green's function approach. In the bulklike region of the sample, this approach captures the intrinsic spin Hall effect found in other calculations. Near the surfaces, the results reveal qualitative differences with the results of the widely used spin-diffusion model, even when the boundary conditions are modified to try to account for them. One difference is that the effective spin-diffusion length for transverse spin transport is significantly different from its longitudinal counterpart and is instead similar to the mean-free path. This …
Information Needs And Use Of E-Resources By The Govt.Nursing Students In The Digital Environment Of Bhubaneswar,Odisha: An Analysis, Payel Saha, Pushpanjali Jena
Information Needs And Use Of E-Resources By The Govt.Nursing Students In The Digital Environment Of Bhubaneswar,Odisha: An Analysis, Payel Saha, Pushpanjali Jena
Library Philosophy and Practice (e-journal)
Like all other academic areas, nursing education has expanded both vertically and horizontally. There is a substantial body of literature in the chosen topic area, created using both traditional and modern techniques. Additionally, the methods used to produce knowledge in this particular profession have evolved, which has affected how nursing students throughout the world search for information. The current review's objective is to examine several factors related to nursing students' use of electronic resources for information seeking that have been researched by various researchers throughout the world over a range of time periods. The paper discusses a few key elements …
Localized Cardiac Small Molecule Trajectories And Persistent Chemical Sequelae In Experimental Chagas Disease, Kate Wheeler, Ana Carolina Leão, Krithivasan Sankaranarayanan, Danya A Dean, Shelley S Kane, Ekram Hossain, Jeroen Pollet, Maria Elena Bottazzi, Peter J Hotez, Kathryn M Jones, Laura-Isobel Mccall
Localized Cardiac Small Molecule Trajectories And Persistent Chemical Sequelae In Experimental Chagas Disease, Kate Wheeler, Ana Carolina Leão, Krithivasan Sankaranarayanan, Danya A Dean, Shelley S Kane, Ekram Hossain, Jeroen Pollet, Maria Elena Bottazzi, Peter J Hotez, Kathryn M Jones, Laura-Isobel Mccall
Faculty, Staff and Students Publications
Post-infectious conditions present major health burdens but remain poorly understood. In Chagas disease (CD), caused by Trypanosoma cruzi parasites, antiparasitic agents that successfully clear T. cruzi do not always improve clinical outcomes. In this study, we reveal differential small molecule trajectories between cardiac regions during chronic T. cruzi infection, matching with characteristic CD apical aneurysm sites. Incomplete, region-specific, cardiac small molecule restoration is observed in animals treated with the antiparasitic benznidazole. In contrast, superior restoration of the cardiac small molecule profile is observed for a combination treatment of reduced-dose benznidazole plus an immunotherapy, even with less parasite burden reduction. Overall, …