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Forecasting Engineering Team Capacity And Work Estimates Using Product Roadmaps, Saif Khalaf, Mailys Levassort, Amisha Singh, Kimberly Reardon Nov 2023

Forecasting Engineering Team Capacity And Work Estimates Using Product Roadmaps, Saif Khalaf, Mailys Levassort, Amisha Singh, Kimberly Reardon

Defensive Publications Series

Despite substantial research, deriving work estimates and team capacity for a given software development project continues to be notoriously difficult to get right. This disclosure describes techniques to automatically and rapidly calculate, in the same unit of measure, engineering team capacity and engineering work estimates for a given set of product features. With use of the described techniques, software development projects can be better organized, and engineering talent can spend time on engineering problems rather than on planning. The automated team capacity and work estimate calculations can be more accurate than typical human-generated estimates, and lead to more accurate product …


In-Conference Tool Virtual Assistant With Real Time Speaking Latency, Dongeek Shin Nov 2023

In-Conference Tool Virtual Assistant With Real Time Speaking Latency, Dongeek Shin

Defensive Publications Series

A framework is proposed for reducing latency for real-time speaking applications, such as virtual assistants. The framework utilizes a hybrid scheme between a large language model (LLM) and a small sound model (SSM). The SSM timestamps the end of a user’s verbal query and notifies the transcription engine that the query has ended. The transcription engine will then abort and send the existing set of transcriptions to the LLM for processing without waiting for the buffer to meet the specific value or time. This minimizes the net response time for real time speech-based models due to the reduced latency from …


Meeting Summarization And Alerts For Video Conference Participants, Shiblee Hasan, Kathleen Bryan Nov 2023

Meeting Summarization And Alerts For Video Conference Participants, Shiblee Hasan, Kathleen Bryan

Defensive Publications Series

A technique is proposed for summarizing meetings to help distracted participants transition back into conversations during video conferences. Processing logic may receive, from a video conferencing platform, a video file including multiple frames and audio. The processing logic may determine a period of time where a participant is distracted based on the participant’s body movement, eye movement, and camera settings. This determination can be made using a machine learning model. The processing logic can also generate a summary of the meeting based on received voice input, chat comments, and participant expressions. This summary may be generated using a generative artificial …


Burn-In Compensation With Foveated Rendering Display Nov 2023

Burn-In Compensation With Foveated Rendering Display

Defensive Publications Series

Systems, methods, and devices for compensating image(s) or video(s) data are provided. A device may divide a display panel including a plurality of pixels into one or more estimated blocks including pixels associated with an original image. The device may also calculate stress data separately for the estimated blocks by calculating a stress value of the pixels associated with the estimated block. The device may also generate an accumulated stress data based on an accumulation of stress data. The device may also degrade data associated with the original image to generate compensation data based on the accumulated stress data.


The Student Movement Volume 108 Issue 9: Perfect Landing: Acrofest Comes To Andrews University, Savannah Tyler, Grace No, Lexie Dunham, Madison Vath, Amelia Stefanescu, Nate Miller, Andrew Francis, Anna Rybachek, Katie Davis, Charisse Lapuebla, Ruben Colón, Alyssa Caruthers, Caitlin Adap, Nicole Compton-Gray, Ian Freeman Nov 2023

The Student Movement Volume 108 Issue 9: Perfect Landing: Acrofest Comes To Andrews University, Savannah Tyler, Grace No, Lexie Dunham, Madison Vath, Amelia Stefanescu, Nate Miller, Andrew Francis, Anna Rybachek, Katie Davis, Charisse Lapuebla, Ruben Colón, Alyssa Caruthers, Caitlin Adap, Nicole Compton-Gray, Ian Freeman

The Student Movement v. 108 (2023-2024)

HUMANS

Blessings Outnumbering The Autumn Leaves, Savannah Tyler

The James White Library Archives, Grace No

ARTS & ENTERTAINMENT

A Charlie Brown Thanksgiving!, Lexie Dunham

Art: Reclaiming the Narrative, Madison Vath

A Trip to Detroit Through Nandi Comer's Eyes, Ameilia Stefanescu

NEWS

Taking Flight at Acrofest, Nate Miller

Andrews Celebrates Veterans, Andrew Francis

Instruments of His Peace in a Broken World, Anna Rybachek

IDEAS

Are Aliens Real?, Katie Davis

Stay Vaccinated for the Sassy Man Epidemic, Charisse Lapuebla

The Thanksgiving Debate, Ruben Colón

PULSE

Artificial Intelligence: Are We Playing God?, Alyssa Caruthers

How Mission Work Impacts the Missionary: Advice for SMs, …


Bilodeau, Richard, Maggie Powers Nov 2023

Bilodeau, Richard, Maggie Powers

Querying the Past: LGBTQ Maine Oral History Project Collection

Richard Bilodeau is 54 years old and identifies as a gay man. He grew up in Portland, attending Deering High School. He is married to his partner Scott and they went on their first date in 1988. He studied applied clinical chemistry at the University of Vermont and began his career in the Maine Medical Center lab. He earned his bachelors and master's in business from the University of Southern Maine. Currently, he works as a professor in the School of Business and Honors Program. Over the years, he also had ownership in alternative health and TV programming businesses. He …


Security Datasets For Network Research, Bruce Hartpence, Bill Stackpole, Daryl Johnson Nov 2023

Security Datasets For Network Research, Bruce Hartpence, Bill Stackpole, Daryl Johnson

Data

This document describes the content of the security traffic datasets included in this collection and the conditions under which the packets were collected. These datasets were assembled from 2023 onward. There will be periodic updates or additions to the dataset collection. The current collection includes a variety of nmap intense scans, an Address Resolution Protocol Man in the Middle (ARP MITM) attack, an Internet Control Message Protocol (ICMP) Redirect MITM and an active directory enumeration attack.

New additions include two DNS Covert channel projects. The first builds the covert channel and exploits the DNS TXT resource records. The second includes …


More Evidence Of Tropical Conditions In The Middle Eocene Climatic Optimum (Meco) With New Fossil Woods From North-Central Türkiye, Ünal Akkemi̇k, Fi̇kret Koçbulut, Özlem Toprak, Umut Tunç Nov 2023

More Evidence Of Tropical Conditions In The Middle Eocene Climatic Optimum (Meco) With New Fossil Woods From North-Central Türkiye, Ünal Akkemi̇k, Fi̇kret Koçbulut, Özlem Toprak, Umut Tunç

Turkish Journal of Earth Sciences

Fossil wood descriptions are among the most important indicators in understanding forest structures across geological ages. This study was carried out to obtain new findings about the Middle Eocene Climate Optimum (MECO) period of Anatolia with new samples collected from the Middle Eocene-aged fossil area near Amasya-Göynücek. The fossil area falls into the Göynücek Volcanics in the region. Transverse, radial, and tangential microscopic sections were taken from three new fossil wood samples, and all identifications were performed on these microscopic sections. As a result, the fossil species were identified as Pinuxylon cf. P. tarnocziense, cf. Dichrostachyoxylon zirkelii, and Laurinoxylon perseamimatus …


Almacık Complex-An Exhumed Lower To Middle Crust In Northwest Anatolia, Aral Okay, Andrew R.C. Kylander-Clark, Sarah Sherlock Nov 2023

Almacık Complex-An Exhumed Lower To Middle Crust In Northwest Anatolia, Aral Okay, Andrew R.C. Kylander-Clark, Sarah Sherlock

Turkish Journal of Earth Sciences

The Almacık Complex is a tectonic unit of high-grade metamorphic rocks in the Intra-Pontide Suture Zone in northwest Turkey. It consists mainly of amphibolite, metaultramafic rock, and gneiss, which are intruded by numerous pre-, syn-, and posttectonic felsic veins. The Almacık Complex is variously interpreted as a Cretaceous or Neoproterozoic ophiolite, or a Permian mafic-ultramafic complex representing the middle to lower crust of the Sakarya Zone. Herein, new petrological and geochronological data were presented from the Almacık Complex. Two-pyroxene geothermometry in the metawebsterites indicated that the Almacık Complex has undergone upper amphibolite-facies metamorphism at 750 ± 30 °C and 8 …


A Study On The Magnetite Skarn Mineralization (Gümüşhane, Türkiye): A Magnetic Survey, Ferkan Si̇pahi̇, Münür Burhan Sadiklar, Mehmet Ali̇ Gücer, Ali̇ Aydin, Rasi̇m Taylan Kara Nov 2023

A Study On The Magnetite Skarn Mineralization (Gümüşhane, Türkiye): A Magnetic Survey, Ferkan Si̇pahi̇, Münür Burhan Sadiklar, Mehmet Ali̇ Gücer, Ali̇ Aydin, Rasi̇m Taylan Kara

Turkish Journal of Earth Sciences

Iron (Fe)-skarn mineralizations (Çambaşı, Dereli, Eğrikar, Karadağ, Kopuz, Sekü, Donguldere, Arnastal, Özdil, Ögene, İkizdere, Ovit Dağı, Kartiba, etc.) in the eastern part of the Pontides (NE Türkiye) are accommodated in the Pontide paleomagmatic arc and the eastern part of the Pontides Metallogenic Belt containing numerous various deposits. Fe-skarn mineralization around the Arnastal Plateau (Gümüşhane-Türkiye) is fragmentary in this area, which is covered with plants (grasses, flowers, etc.). Thus, it was attempted to describe the subsurface structures and Fe mineralization using an interpretation of the available geological and existing magnetic data in this area. Granitoid and volcano-sedimentary series (Upper Cretaceous) outcrop …


Mapping Crustal Structure And Deformation Using Gravity Data In The Bursa Basin And Surroundings, Türkiye, Bülent Oruç, Emi̇r Balkan Nov 2023

Mapping Crustal Structure And Deformation Using Gravity Data In The Bursa Basin And Surroundings, Türkiye, Bülent Oruç, Emi̇r Balkan

Turkish Journal of Earth Sciences

The structure and deformation of the Bursa Basin and surroundings was carried out through the interpretation of Bouguer gravity and isostatic residual gravity anomalies. The spectral analysis was carried out on Bouguer anomalies to obtain the average depths of the crustal structure under the Bursa Basin and surroundings. Parker-Oldenburg algorithm was used to estimate the depths of the interface between upper and lower crust with respect to an average depth and density contrast. We used Mallick-Sharma algorithm to separate the regional gravity anomalies from Bouguer anomalies to estimate the isostatic residual gravity anomalies. Euler deconvolution and two-dimensional density contrast distribution …


Interpreting Structural Configuration Of The Sengkang Basin Of Indonesia Using Edge Detection And 3-D Euler Deconvolution To Satellite Gravity Data, Jamhir Safani, Khalil Ibrahim, Wa Deni, Al Rubaiyn, Firdaus Firdaus, Harisma Harisma Nov 2023

Interpreting Structural Configuration Of The Sengkang Basin Of Indonesia Using Edge Detection And 3-D Euler Deconvolution To Satellite Gravity Data, Jamhir Safani, Khalil Ibrahim, Wa Deni, Al Rubaiyn, Firdaus Firdaus, Harisma Harisma

Turkish Journal of Earth Sciences

The East Walanae Fault Zone and the West Walanae Fault Zone are the two active fault segments in the south arm of Sulawesi. These fault segments are responsible for the formation of the Sengkang Basin. This geological complexity makes the Sengkang Basin a very interesting area to study. This research aims to (1) identify basin boundaries and lithological contacts; (2) estimate the positions of fault segments; and (3) model the basement beneath the Sengkang Basin. The free-air gravity anomaly from the GGMPlus dataset is employed and then corrected using Bouguer and terrain corrections to provide the complete Bouguer gravity anomaly …


Middle Eocene Alveolina-Dominated Benthic Foraminiferal Assemblages Of The Western Flank Of The Isparta Angle (Sw Türkiye): Taxonomy, Biostratigraphy, Microfacies Analysis, And Paleoenvironmental Implications, Alper Bozkurt, Muhi̇tti̇n Görmüş, Banu Türkmen Bozkurt Nov 2023

Middle Eocene Alveolina-Dominated Benthic Foraminiferal Assemblages Of The Western Flank Of The Isparta Angle (Sw Türkiye): Taxonomy, Biostratigraphy, Microfacies Analysis, And Paleoenvironmental Implications, Alper Bozkurt, Muhi̇tti̇n Görmüş, Banu Türkmen Bozkurt

Turkish Journal of Earth Sciences

Middle Eocene formations of the western part of the Isparta Angle contain abundant larger benthic foraminifera (LBF). Twelve species belonging to the genus Alveolina, including A. callosa, A. fragilis, A. aff. fusiformis, A. gigantea, A. cf. gigantea, A. hottingeri, A. kieli, A. levantina, A. nuttalli, A. cf. obtusa, A. stipes, and A. tenuis have been identified throughout the two measured sections from Dinar and Çardak (SW Türkiye). The investigated assemblages, consisting also of nummulitids, orthophragminids, textulariids, rotaliids, and miliolids, allow us to assign the Suçıkan section to shallow benthic zone 13 (SBZ13) and the Karabayır section to SBZ17. Based on …


Digital Construction Annual Survey 2022 Report, Davitt Lamon, Ted Mckenna Nov 2023

Digital Construction Annual Survey 2022 Report, Davitt Lamon, Ted Mckenna

Reports

The Annual Survey 2022 was conducted to assess the state of digital transformation in the Irish construction and built environment sector. This report presents the analysis of survey data, with a focus on implications for the Build Digital project and Build Digital’s five pillars: Digital Leadership & Cultural Change, Digital Standards, Digital Education & Training, Digital Procurement, and Sustainability & Circular Economy. Key findings from the survey indicated that a significant number of organisations have started their digital transformation journey, with many identifying themselves as proactive and possessing a clear business-focused strategy. However, a considerable cohort of respondents are keen …


Ways To Prevent Moral Disengagement For Youtube Content Creators: The Role Of Empathy And Self-Compassion, Nathan Andrew Pennington Nov 2023

Ways To Prevent Moral Disengagement For Youtube Content Creators: The Role Of Empathy And Self-Compassion, Nathan Andrew Pennington

Dissertations

This study sought to assess the role empathy and self-compassion play in lessening the impact of stress and moral disengagement for digital entrepreneurs, specifically, YouTube content creators. The desire for status and the need for venture legitimacy within the content creation economy, while considered mostly positive traits, can be taken to the extreme, leading to a lack of empathy and self-compassion and even degradation and moral disengagement. The study utilized a mixed-methods approach, combining quantitative and qualitative data collection techniques. Quantitative data within the study provides statistical evidence of correlations and trends, while qualitative data discusses the perspectives and lived …


Brodack, Jason, Emily Cook Nov 2023

Brodack, Jason, Emily Cook

Querying the Past: LGBTQ Maine Oral History Project Collection

Jason Brodak is a 44 year old man of Polish heritage, currently working at the University of Southern Maine and living in Bath, Maine, with his husband. Brodak discusses living in Detroit Michigan, Chicago Illinois, and New York. He attended Michigan State University and later received his bachelor's degree in Interior Design from an arts school in Chicago. He discusses his childhood, coming out, briefly joining the Navy, the role of gay bars and gay chatrooms in his life, gay marriage, and the HIV AIDS epidemic.

Please cite as: Querying the Past: LGBTQ Maine Oral History Project Collection, Lesbian, Gay, …


November 17, 2023 Ereporter, University Of Alabama At Birmingham Nov 2023

November 17, 2023 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.


2023 November 17 - Board Of Trustees Agenda And Minutes, Board Of Trustees, East Tennessee State University Nov 2023

2023 November 17 - Board Of Trustees Agenda And Minutes, Board Of Trustees, East Tennessee State University

Board of Trustees Agendas and Minutes

No abstract provided.


Sustainability And Circular Economy Horizon Scan And Needs Analysis, Sadaf Dalirazar, Mark Kelly, Derek Sinnott, James O'Donnell Nov 2023

Sustainability And Circular Economy Horizon Scan And Needs Analysis, Sadaf Dalirazar, Mark Kelly, Derek Sinnott, James O'Donnell

Reports

The construction industry plays a crucial role in addressing the climate crisis as it is the largest global consumer of raw materials and contributes significantly to global energy consumption and emissions. Considering the world’s continuous population growth and the imperative to address infrastructure and housing demands the construction sector needs to adopt further sustainable strategies in its activities to reduce the pressure on natural resources. In addition, the Architecture, Engineering, and Construction (AEC) sector is responsible for generating substantial amount of waste known as Construction and Demolition Waste (CDW), which is projected to increase due to the future construction developments. …


Scoring Soar, Timothy J. Bartik Nov 2023

Scoring Soar, Timothy J. Bartik

Upjohn Institute Policy Papers

This paper estimates the benefits and costs of the incentive package provided to the proposed Ford battery plant in Marshall, Michigan. This project, announced in February 2023, involves a state and local business incentive package whose undiscounted value is $1.7 billion, and which is awarded to a plant that will eventually create 2,500 permanent jobs. The incentive package is analyzed using the Bartik Benefit-Cost Model of Incentives. The model’s estimates suggest that the incentive package has economic benefits whose present value is over 1.8 times the project’s incentive costs. Most of these benefits are higher earnings per capita for Michigan …


2023 November 17 - Board Of Trustees Academic, Research, And Student Success Committee Agenda And Minutes, Board Of Trustees, East Tennessee State University Nov 2023

2023 November 17 - Board Of Trustees Academic, Research, And Student Success Committee Agenda And Minutes, Board Of Trustees, East Tennessee State University

Board of Trustees Agendas and Minutes

No abstract provided.


Energy Analysis Of The Integration Of Hrv And Direct Evaporative Cooling For Energy Efficiency In Buildings: A Case Study In Iraq, Husham Al-Naseri, Robert Fryer, Ali Samir Nov 2023

Energy Analysis Of The Integration Of Hrv And Direct Evaporative Cooling For Energy Efficiency In Buildings: A Case Study In Iraq, Husham Al-Naseri, Robert Fryer, Ali Samir

College of Architecture and the Built Environment Faculty Papers

Responding to climate change and adapting to global warming requires creative solutions. In Iraq, the most reliable and popular tool to have buildings cooled is airconditioning units (AC). While an evaporative cooler is not enough to achieve thermal comfort in a very hot climate, AC units consume a lot of energy which causes a significant load on the grid in Iraq resulting in increasing the emissions of CO2. This paper investigates the potential energy-saving associated with adopting a new arrangement of heat recovery ventilation (HRV) unit and evaporative cooler to achieve thermal comfort with far less energy. Two sets of …


Cognitive Engagement During Group Learning Activities In Chemistry Courses: An Analysis Of Student Discourse, Safaa Youssef El-Mansy Nov 2023

Cognitive Engagement During Group Learning Activities In Chemistry Courses: An Analysis Of Student Discourse, Safaa Youssef El-Mansy

Dissertations and Theses

As educators, our goal is to help our students be successful, but in order to accomplish this, we need to understand what factors contribute to student success. One factor, small-group active learning, has been correlated to improved academic outcomes; however, the magnitude of this improvement can vary across different courses, different types of group work, and even across courses that use the same group work structure. Therefore, it is important to understand what aspects of group work contribute to its effectiveness. The work presented in this dissertation investigated one specific aspect: students’ cognitive engagement. This was done by analyzing the …


Oregon Transportation Plan: Innovations In The Exploratory Scenario Planning Approach, Adam Argo, Jonathan Slason Nov 2023

Oregon Transportation Plan: Innovations In The Exploratory Scenario Planning Approach, Adam Argo, Jonathan Slason

PSU Transportation Seminars

This seminar reviews the recently-adopted Oregon Transportation Plan and the process and innovations that underpinned the analysis to identify a preferred set of investments and actions to support the vision and goals of the plan. The plan used innovative methods for communicating how investment strategies may affect regions or example households across the state. Funding is a key influence on how the plan by identifying the affects of inadequate funding and identifying how investment priorities change if funding increases. The Statewide VisionEval strategic travel model was used to conduct an exploratory scenario planning process that informed the relationships between funding, …


Review: Expanding Writing Center Research With Discourse Analysis, Sara Swaim, Randall W. Monty Nov 2023

Review: Expanding Writing Center Research With Discourse Analysis, Sara Swaim, Randall W. Monty

The Writing Center Journal

Corpus-assisted discourse studies (CADS) is a growing field of study that provides for holistic understandings of written texts, spoken discourse, rhetorical strategies, and the people who use them. Organized as a discussion of the topics, methods, and their potential applications for writing center research, this essay reviews three edited collections, Corpus Approaches to Discourse: A Critical Review by Charlotte Taylor and Anne Marchi (Routledge, 2018); The Routledge Handbook of Corpus Approaches to Discourse Analysis by Eric Friginal and Jack A. Hardy (Routledge, 2020); and Research Methods for Digital Discourse Analysis by Camilla Vásquez (Bloomsbury, 2022). Each introduces a range of …


Destigmatizing Working With Dyslexic Learners, Riley N. Dandurand Nov 2023

Destigmatizing Working With Dyslexic Learners, Riley N. Dandurand

The Writing Center Journal

In the field of writing center research there is a paucity of information regarding tutoring students with dyslexia. This comes as no surprise considering it is only in the last 50 years that there has been a conscious effort to include those who have exceptionalities in all areas of education. In addition to a lack of research and training there is another issue that arises with disclosing exceptionalities. Those studying dyslexia have found that students are hesitant to disclose their learning disability because of the stigma and feelings of differentiation from their peers (Brizee et al., 2012). The question then …


An Intersection Of Science & Art: Vitrification Approaches And Open-Fabricated Tools For The Biomedical Model Sea Hare, Aplysia Californica, Allyssa M. Oune Nov 2023

An Intersection Of Science & Art: Vitrification Approaches And Open-Fabricated Tools For The Biomedical Model Sea Hare, Aplysia Californica, Allyssa M. Oune

LSU Master's Theses

The California sea hare (Aplysia californica) is an important biomedical model for molecular neurobiology, electrophysiology, learning, and memory due to their well-mapped and large neurons and well-characterized learning capabilities. The National Resource for Aplysia (NRA, University of Miami) maintains large stocks of live animals and relies on regular shipments of wild-caught individuals to maintain genetic diversity. This is labor and cost-intensive, and environmental changes could alter the availability of wild animals increasing the need to preserve this genetic resource. One solution is vitrification, ultra-fast cooling which produces an amorphous glass that minimizes damage to cells. Aplysia californica presents …


Multi-Site Identification And Generalization Of Clusters Of Walking Behaviors In Individuals With Chronic Stroke And Neurotypical Controls, Natalia Sanchez, Nicolas Schweighofer, Sara J. Mulroy, Ryan T. Roemmich, Tricia M. Kesar, Gelsy Torres-Oviedo, Beth E. Fisher, James M. Finley, Carolee J. Winstein Nov 2023

Multi-Site Identification And Generalization Of Clusters Of Walking Behaviors In Individuals With Chronic Stroke And Neurotypical Controls, Natalia Sanchez, Nicolas Schweighofer, Sara J. Mulroy, Ryan T. Roemmich, Tricia M. Kesar, Gelsy Torres-Oviedo, Beth E. Fisher, James M. Finley, Carolee J. Winstein

Physical Therapy Faculty Articles and Research

Background

Walking patterns in stroke survivors are highly heterogeneous, which poses a challenge in systematizing treatment prescriptions for walking rehabilitation interventions.

Objectives

We used bilateral spatiotemporal and force data during walking to create a multi-site research sample to: (1) identify clusters of walking behaviors in people post-stroke and neurotypical controls and (2) determine the generalizability of these walking clusters across different research sites. We hypothesized that participants post-stroke will have different walking impairments resulting in different clusters of walking behaviors, which are also different from control participants.

Methods

We gathered data from 81 post-stroke participants across 4 research sites and …


National Legal Models To Regulate Scrubbers Washwater, Shams Al Din Al Hajjaji Nov 2023

National Legal Models To Regulate Scrubbers Washwater, Shams Al Din Al Hajjaji

Loyola of Los Angeles International and Comparative Law Review

According to the findings of this study, nations should adopt uniform regulations regarding the discharge of washwater from exhaust gas cleaning systems into their ports, territories, and Exclusive Economic Zones. Scrubbers are used by ships to reduce their emissions of greenhouse gases so they can adhere to the International Maritime Organization’s limit on the sulfur content of ship fuel. The global upper limit was 0.5% in January 2020. Scrubber washwater is discharged into the ocean by ships. Toxic substances are present in the washwater for the scrubbers. The level of washwater for the scrubbers is governed by the 2008 and …


Mechanisms Of Endothelial Cell Membrane Repair: Progress And Perspectives., Duoduo Zha, Shizhen Wang, Paula Monaghan-Nichols, Yisong Qian, Venkatesh Sampath, Mingui Fu Nov 2023

Mechanisms Of Endothelial Cell Membrane Repair: Progress And Perspectives., Duoduo Zha, Shizhen Wang, Paula Monaghan-Nichols, Yisong Qian, Venkatesh Sampath, Mingui Fu

Manuscripts, Articles, Book Chapters and Other Papers

Endothelial cells are the crucial inner lining of blood vessels, which are pivotal in vascular homeostasis and integrity. However, these cells are perpetually subjected to a myriad of mechanical, chemical, and biological stresses that can compromise their plasma membranes. A sophisticated repair system involving key molecules, such as calcium, annexins, dysferlin, and MG53, is essential for maintaining endothelial viability. These components orchestrate complex mechanisms, including exocytosis and endocytosis, to repair membrane disruptions. Dysfunctions in this repair machinery, often exacerbated by aging, are linked to endothelial cell death, subsequently contributing to the onset of atherosclerosis and the progression of cardiovascular diseases …