Digital Commons Network^™

Changes In Quality And Flavor Of Frozen Semi-Dried Pomfret Under Simulated Logistics And Transportation Conditions, Duan Rubi, He Yanfu, Qiu Dan, Xia Guanghua, Li Yongcheng

Food and Machinery

Objective: This study aimed to investigate the changes in quality and flavor of semi-dried gold pomfret during the thawing process of logistics transportation. Methods: The logistics transportation process of frozen semi-dried gold pomfret was simulated at different temperatures. The thawing-loss rate, changes in myofibrillar protein conformation, physical and chemical indexes of protein, lipid oxidation and changes in flavor substances were determined. Results: The protein and lipid oxidation degrees of pomfret were significantly increased with the extension of transport time (P＜0.05). The oxidation degree was (P＜0.05) more significant as the temperature increased. During this process, protein aggregation …

Information-Rich 6d Single-Molecule Imaging Design Using Optimization, Tingting Wu

McKelvey School of Engineering Graduate Student Theses & Dissertations

When studying biochemical processes, localizing the targets alone will not paint a complete picture. We also need techniques to probe how biomolecules interact with one another, including how molecules are organized into larger structures, how they are oriented with respect to surrounding molecules, and how local chemical parameters, like pH and hydrophobicity, vary spatially and temporally. My dissertation focuses on single-molecule orientation localization microscopy (SMOLM, Chapter 1). The objective is to develop imaging techniques for measuring how molecules are oriented with respect to their surrounding molecules, namely, 3D orientation. Achieving optimal imaging performance requires careful design of both the forward …

Determination Of 5 Kinds Of Biogenic Amines In Cheeses By High Performance Liquid Chromatography-Tandem Mass Spectrometry, Zhang Hui, Cao Hui, Wang Jin, Xiao Gongnian, Jiang Kan

Food and Machinery

Objective: A new technical idea was provided for the study of biogenic amine formation mechanism and food safety risk assessment. Methods: An analytical method was established for determination of tyramine, phenylethylamine, tryptamine, octopamine and cadaverine in cheeses with high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS). Biogenic amines were extracted by ultrasonic-assisted solvent extraction from cheeses, and were separated by HILIC column, determined by positive electrospray ionization (ESI) with multiple reaction monitoring (MRM) mode, quantified by the internal standard method. The effect of extraction solvent type, ultrasonic time and matrix effect on the peak area was studied, and the performance of …

Numerical Simulation Of Factors Affecting Flow Characteristics Of Double-Circular-Arc Gear Pump, Huang Cheng, Xu Kai, Wei Zhibo, Li Geqiang

Food and Machinery

Objective: Analyzed the influencing factors of the internal flow field pulsation characteristics of the new double circular arc gear pump, and adopt reasonable parameters to improve the output efficiency of the gear pump. Methods: The two-dimensional flow field simulation model of the gear pump was established, and the computational fluid dynamics software Fluent was used for simulation analysis to study the influence of different tip clearance, different gear eccentricity, load and speed on the instantaneous flow, flow pulsation and flow field characteristics of the oil outlet of the gear pump. Results: As the tooth tip clearance increased, the outlet flow …

Progress In The Effect Of Oligosaccharide Modification On Gelability Of Egg White Protein, Zhang Gensheng, Su Wenwen, Xu Guiyang, Su Lirui, Fei Yingmin

Food and Machinery

Egg white protein is a high-quality protein with high nutritional value and a variety of functional properties. The oligosaccharides can be covalently bound to the egg white protein through the glycosylation reaction, and the functional properties of the conjugates were improved compared with the natural egg white protein. In this review, the gel mechanism of oligosaccharide-egg white protein conjugates was reviewed, and the influencing factors of oligosaccharide-modified egg albumin gels were discussed. Moreover, effects of oligosaccharides on the functional properties of egg albumins were summarized, and the processing and application of oligosaccharide-modified egg albumin were prospected.

Study On The Effect Of Ultrasonic Aging Of Crude Baijiu After Second Distillation, Zhang Yingying, Chen Xuepeng, Yu Yougui, Tan Wenjun, Wu Jinlan, Dai Shan, Zheng Qing

Food and Machinery

Objective: Accelerated manmade aging of base liquor after heavy distillation. Methods: A single factor experimental design method was adopted based on the study of impurity removal in second distillation of Luzhou-flavor crude Baijiu. The changes in the content of total acids and total esters in the liquor were used as indicators to preliminarily explore the effect of ultrasonic treatment conditions on the crude Baijiu. Results: The results showed that: among the three single factors of ultrasonic treatment power, temperature and time, there were varying degrees of differences between the levels of each individual factor; At an ultrasonic frequency of 45 …

Passive Physical Layer Distinct Native Attribute Cyber Security Monitor, Christopher M. Rondeau, Michael A. Temple, Juan L. Lopez Jr., J. Addison Betances

AFIT Patents

A method for cyber security monitor includes monitoring a network interface that is input-only configured to surreptitiously and covertly receive bit-level, physical layer communication between networked control and sensor field devices. During a training mode, a baseline distinct native attribute (DNA) fingerprint is generated for each networked field device. During a protection mode, a current DNA fingerprint is generated for each networked field device. The current DNA fingerprint is compared to the baseline DNA fingerprint for each networked field device. In response to detect at least one of RAA and PAA based on a change in the current DNA fingerprint …

Stabilizing Vimentin Phosphorylation Inhibits Stem-Like Cell Properties And Metastasis Of Hybrid Epithelial/Mesenchymal Carcinomas, Nick A Kuburich, Petra Den Hollander, Maria Castaneda, Mika Pietilä, Ximing Tang, Francisco Martínez-Peña, Tieling Zhou, Breanna R Demestichas, Ritesh V Dontula, Jojo Y Liu, Joanna Joyce Maddela, Reethi S Padmanabhan, Lan Thi Hanh Phi, Matthew J Rosolen, Thiru Sabapathy, Dhiraj Kumar, Filippo G Giancotti, Luke L Lairson, Maria Gabriela Raso, Rama Soundararajan, Sendurai A Mani

Faculty, Staff and Student Publications

Epithelial-mesenchymal transition (EMT) empowers epithelial cells with mesenchymal and stem-like attributes, facilitating metastasis, a leading cause of cancer-related mortality. Hybrid epithelial-mesenchymal (E/M) cells, retaining both epithelial and mesenchymal traits, exhibit heightened metastatic potential and stemness. The mesenchymal intermediate filament, vimentin, is upregulated during EMT, enhancing the resilience and invasiveness of carcinoma cells. The phosphorylation of vimentin is critical to its structure and function. Here, we identify that stabilizing vimentin phosphorylation at serine 56 induces multinucleation, specifically in hybrid E/M cells with stemness properties but not epithelial or mesenchymal cells. Cancer stem-like cells are especially susceptible to vimentin-induced multinucleation relative to …

Aortic Valve Leaflets Are Asymmetric And Correlated With The Origin Of Coronary Arteries, Megan Childress, Antonio F Corno

Faculty, Staff and Student Publications

BACKGROUND: Asymmetry of the aortic valve leaflets has been known since Leonardo Da Vinci, but the relationship between size and shape and origin of the coronary arteries has never been examined. Our aim was to evaluate this anatomy in a population of pediatric patients using a cross-sectional study design.

METHODS: Consecutive pediatric patients with trans-esophageal echocardiography (TEE), with or without trans-thoracic echocardiography (TTE), were included in our study. Exclusion criteria: (I) bicuspid aortic valve; (II) aortic valve stenosis; (III) hypoplasia of aortic valve annulus, or aortic root; (IV) truncal valve; (V) coronary artery atresia; (VI) previous surgery on aortic valve …

Genomic Loci Influence Patterns Of Structural Covariance In The Human Brain, Junhao Wen, Aristeidis Sotiras, Daniel S Marcus, Pamela Lamontagne, John C Morris, Et Al.

2020-Current year OA Pubs

Normal and pathologic neurobiological processes influence brain morphology in coordinated ways that give rise to patterns of structural covariance (PSC) across brain regions and individuals during brain aging and diseases. The genetic underpinnings of these patterns remain largely unknown. We apply a stochastic multivariate factorization method to a diverse population of 50,699 individuals (12 studies and 130 sites) and derive data-driven, multi-scale PSCs of regional brain size. PSCs were significantly correlated with 915 genomic loci in the discovery set, 617 of which are newly identified, and 72% were independently replicated. Key pathways influencing PSCs involve reelin signaling, apoptosis, neurogenesis, and …

Engineered Adoptive T-Cell Therapies For Breast Cancer: Current Progress, Challenges, And Potential

Faculty, Staff and Students Publications

Breast cancer remains a significant health challenge, and novel treatment approaches are critically needed. This review presents an in-depth analysis of engineered adoptive T-cell therapies (E-ACTs), an innovative frontier in cancer immunotherapy, focusing on their application in breast cancer. We explore the evolving landscape of chimeric antigen receptor (CAR) and T-cell receptor (TCR) T-cell therapies, highlighting their potential and challenges in targeting breast cancer. The review addresses key obstacles such as target antigen selection, the complex breast cancer tumor microenvironment, and the persistence of engineered T-cells. We discuss the advances in overcoming these barriers, including strategies to enhance T-cell efficacy. …

Co-Transmitting Interneurons In The Mouse Olfactory Bulb Regulate Olfactory Detection And Discrimination, Mikhail Y Kochukov, Benjamin D W Belfort, Joshua Ortiz-Guzman, Zachary Freyberg, Benjamin R Arenkiel

Faculty, Staff and Students Publications

Co-transmission of multiple neurotransmitters from a single neuron increases the complexity of signaling information within defined neuronal circuits. Superficial short-axon cells in the olfactory bulb release both dopamine and γ-aminobutyric acid (GABA), yet the specific targets of these neurotransmitters and their respective roles in olfaction have remained unknown. Here, we implement intersectional genetics in mice to selectively block GABA or dopamine release from superficial short-axon cells to identify their distinct cellular targets, impact on circuit function, and behavioral contribution of each neurotransmitter toward olfactory behaviors. We provide functional and anatomical evidence for divergent superficial short-axon cell signaling onto downstream neurons …

Isolation And Characterization Of Microbes From Agricultural Fields And Their Evaluation For The Control Of Plant Pests, Hira Liaqat Ali, Sumaira Mazhar, Afeefa Chaudhry

Journal of Bioresource Management

Plant diseases due to pests cause huge loss to crop fields every year. For the control of plant pest, pesticides are under use. Fusarium wilt is caused by phytopathogen Fusarium oxysporum. More than 100 species were affected due to this disease caused by this virus. Fungi also affect onion plant crop yield every year, when chemical pesticides are applied to onion crop field. It will increase the cost of onion production and it is also dangerous for the environment and living organism other than the targeted pests. A number of microorganisms like fungi, bacteria and nematode are currently being …

System And Method For Secure Authentication Based On An Attribute Value, Anil Kumar Japa

Defensive Publications Series

The present disclosure relates to a method and system for secure authentication of user devices based on an attribute value. The present disclosure suggests updating a new temporary attribute value when a user performs actions like locking, or shutting down a user device. Thereafter, an authenticated application or resource is accessed using the decrypted value, wherein the decrypted value is used to obtain the current HostName lock status value. If the current HostName lock status value is not the same as the predefined value in a decrypted string, access to the authenticated application resources is allowed, otherwise access is restricted. …

Email Scanning Optimization Techniques, Suresh Gopathy, Gajendar Pandey

Defensive Publications Series

Typically, a Secure Mailbox (SM) or Secure Email Gateway (SEG) that receives emails for an organization scans emails and performs threat detection/handling for the emails (e.g., allowing or dropping emails) based on various handling policies configured for the organization. Currently, an SM/SEG completely scans all email each time an email traverses the SM/SEG (e.g., for an initial email and any subsequent replies/responses for a conversation/email thread), which can result in high usage of compute resources for an organization, potentially increasing the cost of email services, as well as increasing the latency of email delivery. In order to address such issues, …

Table Of Contents, The Editors

Coal Geology & Exploration

No abstract provided.

Critical Links And Development Trends Of Research On Active Tectonics, Yuan Daoyang, Wang Youlin, Li Shuwu, Wang Wanhe, Li Linyuan, Zou Xiaobo, Wen Yameng

Coal Geology & Exploration

Following a brief introduction of the general characteristics of active tectonics in China, this study analyzed two new features of large earthquakes with M_s ≥ 7 that have struck continental China since the beginning of the 21st century: (1) Large earthquakes occur primarily in clusters along the boundary fault zone of the Bayanhar active tectonic block—part of the Qinghai-Tibet ateau active tectonic block. (2) Reverse fault-fold earthquakes have occurred multiple times within active basins or at basin-mountain boundaries. In response to the new seismic activity features and the new demand for disaster prevention and mitigation of engineering construction and …

Activity Variations Of The Shanzuokou-Sihong Fault Within The Jiangsu Segment Of The Tancheng-Lujiang Fault Zone And Their Origins, Zhang Hao, Li Wei, Li Limei, Yan Yunxiang, Jiang Xin, Wang Jinyan, Zhao Qiguang, Gu Qinping, Xu Hangang

Coal Geology & Exploration

The Shanzuokou-Sihong fault, having undergone the entire evolutionary process of the Tancheng-Lujiang fault zone, exhibits segmentation during the latest activity epoch. Determining the location and origin of its activity segmentation will provide a significant reference for exploring the activity variations of its branch faults and their origins. This study investigated the activity of the Shanzuokou-Sihong fault using a three-dimensional approach combining field geological surveys, shallow seismic exploration, and cross-well stratigraphic correlation. The results show that the Shanzuokou-Sihong fault is a Late Pleistocene active fault on the east side of the North Maling Mountain and a Middle Pleistocene fault in Xinyi …

Revealing Fine-Scale Crustal Structure And Tectonic Features In The Xiong’An New Area And Its Periphery Using Deep Seismic Reflection Profiling, Yue Hangyu, Wang Kai, Wang Xiaojiang, Zhang Baowei, Zhang Kai

Coal Geology & Exploration

As an effective method to accurately reveal the deep geological structures and tectonic features of the Earth, deep seismic reflection profiling has been increasingly applied to the exploration of the continental and oceanic crusts, as well as the upper mantle of the lithosphere, making it internationally recognized pioneer technique for deep Earth exploration. This study examined the deep seismic reflection profile spanning across the Xiong’an New Area in Hebei Province, aiming to reveal the crustal structure and tectonic features of the study area. Key findings are as follows: (1) The crust in the study area can be divided into the …

Application Of Integrated Geophysical Surveys In The Identification Of Hidden Fire Sources In Spontaneous Combustion Zones In Coal Seams, Ma Zijun, Yang Haiyan, Li Wenyu, Xu Yunlei, He Yunlan, Liu Zhuoming, Li Peng, Huang Jiu

Coal Geology & Exploration

Spontaneous combustion in coal seams, a factor influencing the development of many mining areas in China, can cause severe coal resource loss and environmental pollution. The positioning and distribution identification of hidden fire sources can provide an important basis for coal mine enterprises to prepare prevention and control measures. They are also a hot research topic and challenge in the field of coal fire disasters. Suitable channels for ventilation and oxygen supply are necessary for spontaneous combustion in coal seams. When the oxidative heat release rate of coals exceeds the heat dissipation rate, coal temperature will rise until the occurrence …

Clinically Effective Regenerative Therapy For Primary Endodontic Lesions With Secondary Periodontal Lesions: A Case Report, Martina Amalia, Budi Budi, Iceu Estu Kurmaena, Nevi Yanti, Hesty Nurcahyanti, Aini Hariyani Nasution

Journal of Dentistry Indonesia

The diagnosis and prognosis of teeth with endo-perio lesions present a major challenge for dentists. Proper diagnosis is critical in determining treatment and the long-term prognosis. However, treating complex endodontic and periodontal lesions is one of the most common challenges in current clinical practice. The coexistence of pulpal and periodontal tissue damage may complicate diagnosis and further influence dental prognosis. This article consists of a case report evaluating the efficacy of xenografts and resorbable membrane pericardium in treating bifurcation lesions associated with periodontal lesions of the left mandibular first molar. A 22-year-old female patient was referred by conservative dentistry with …

Chromium-Contaminated Sites: Migration Characteristics And Monitoring Using Dual-Frequency Ip Method, Wei Kaiyao, Liu Zhimin, Liang Chen, Zhang Jie, Ma Qiang

Coal Geology & Exploration

Given that the migration process of chromium-contaminated sites is subjected to various uncertainties, it is difficult to investigate the migration characteristics and explore the monitoring process using experiments. Based on the basic law of groundwater flow and the migration mechanisms of pollutants, this study conducted a simulation analysis of the migration characteristics of static chromium contamination sources and the law of changes in the migration characteristics using the COMSOL software. Then, this study verified the reliability and accuracy of numerical forward simulations through physical simulation experiments on a static soil bin. Specifically, using the model of chromium contamination source migration …

Dual-Frequency Transmission Radio Wave-Based Exploration Method And Its Application, Fu Xianjie, Hu Ze'an, Wu Rongxin, Li Peng

Coal Geology & Exploration

Coal seams can act as the guided wave layers of high-frequency electromagnetic waves, and radio wave perspective technology can be used to detect geological structures within coal seams of a working face. Presently, radio wave perspective methods usually use a single frequency, leading to some problems such as improper frequency selection and limited detection accuracy in the exploration of mining faces. In response, this study developed a dual-frequency transmission radio wave-based exploration method. Based on theoretical analysis, as well as the field strength of dual-frequency perspective and attenuation coefficient, this study derived the calculation formula for the absorption factor γ …

The Application Of The Opposing Coils Transient Electromagnetic Method And Microtremor Survey Method In Shallow Karst Detection, Zhang Xueliang, Xie Tao, Zhou Wei, Gao Hui, Deng Dong, Qu Jingyi

Coal Geology & Exploration

Concealed karsts frequently lead to disasters such as ground collapse, water reservoir seepage, and tunnel water inrush. Identifying the distribution and development of karsts in advance holds great significance for guiding engineering design and construction in karst areas. Geophysical methods rank among the most effective methods for karst detection. Given the problems of karst development, limited space, and serious electromagnetic interference in the tank farms of the Longkou Port, Shandong Province, this study explored shallow karsts in these farms through the joint application of the opposing coils transient electromagnetic (OCTEM) method and the microtremor survey method. Firstly, surface scanning was …

The 2023 Orthopedic Research Society's International Consensus Meeting On Musculoskeletal Infection: Summary From The In Vitro Section, Noreen J. Hickok, Bingyun Li, Ebru Oral, Sebastian A.J. Zaat, David A. Armbruster, Gerald J. Atkins, Antonia F. Chen, Débora C. Coraça-Huber, Tianhong Dai, Edward M. Greenfield, Rajendra Kasinath, Matthew Libera, Cláudia N.H. Marques, T. Fintan Moriarty, K. Scott Phillips, Kapil Raghuraman, Dacheng Ren, Lia Rimondini, Kordo Saeed, Thomas P. Schaer, Edward M. Schwarz, Christopher Spiegel, Paul Stoodley, Vi Khanh Truong, Shao-Ting Jerry Tsang, Britt Wildemann, Anja R. Zelmer, Annelies S. Zinkernagel

Department of Orthopaedic Surgery Faculty Papers

Antimicrobial strategies for musculoskeletal infections are typically first developed with in vitro models. The In Vitro Section of the 2023 Orthopedic Research Society Musculoskeletal Infection international consensus meeting (ICM) probed our state of knowledge of in vitro systems with respect to bacteria and biofilm phenotype, standards, in vitro activity, and the ability to predict in vivo efficacy. A subset of ICM delegates performed systematic reviews on 15 questions and made recommendations and assessment of the level of evidence that were then voted on by 72 ICM delegates. Here, we report recommendations and rationale from the reviews and the results of …

Advances In Research On Active Faults And Exploration Of Relevant Frontier Scientific Problems, Xu Xiwei, Li Feng, Cheng Jia, Liu Baojin, Chen Guihua, Li Kang, Ren Junjie, Jia Qichao

Coal Geology & Exploration

This study reviewed the approval and initiation processes and major research contents of China's active fault-related projects, such as the urban active fault survey projects, large-scale mapping programs of active faults, and the earthquake hazard assessment of active faults in key earthquake monitoring and prevention areas. By combining the scientific investigation results of the surface rupture zones induced by strong earthquakes over the past 20 years, this study elaborated on significant advances achieved in the following aspects: the survey and positioning techniques for concealed active faults under strong-noise and weak-signal conditions, the quantitative identification techniques for fault activity, theories and …

Optimization Of Data Acquisition Parameters For Deep Seismic Reflection Surveys In Complex Terrain, Yan Yunxiang, Li Pei, Zhi Min, Liu Jianda, Wang Zichen, Zhang Ying, Pei Gendi, Li Linyuan, Mou Qi, Jia Jin

Coal Geology & Exploration

Fujian, located in the orogen region of the coastal areas of southeast China, exhibits well-developed structures and complex surface conditions, which make deep seismic reflection surveys challenging. In response to the diversity and complexity of seismogeological conditions in Fujian, this study optimized the seismic excitation means based on previous deep seismic surveys. Specifically, the combination of large, medium, and small guns was transitioned into the layout of normal guns (spacing of shot points: 600 m) and large shots (spacing of shot points: 15 km), leading to enhanced folds of large shots. Through simulation analysis, this study calculated the spacing of …

Mechanical Behavior And Failure Response Characteristics Of Hard Sandstones Considering Bedding Dip Angles, Song Zhanping, Liu Hongke, Zheng Fang, Cheng Yun, Sun Yinhao, Song Wanxue

Coal Geology & Exploration

This study focuses on the mechanical behavior and failure responses of hard sandstones considering bedding dip angles. Through uniaxial compression tests of hard sandstones with different bedding dip angles, this study delved into the influence of bedding dip angles on the mechanical behavior of hard sandstones and the relationship between the bedding dip angles and fractal characteristics of hard sandstone fragments. The test results show that bedding dip angles produced negligible effects on the type of the stress-strain curves of hard sandstones. However, low dip angles (0°, 22.5°, and 45°) corresponded to unimodal curves, while high dip angles (67.5° and …

Prevalence And Clinical Characteristics Of Temporomandibular Disorders In Adults: An Epidemiological Study In The Mediterranean Region Of Türkiye, Esra Yavuz, Selmi Yardimci, Humeyra Tercanli

Journal of Dentistry Indonesia

The prevalence and clinical characteristics of temporomandibular disorders (TMD) in the Mediterranean region of Türkiye have not yet been thoroughly investigated. Objective: This study aimed to determine the prevalence and severity of TMD in a sample of the population in this region and to characterize the clinical findings related to TMD. Methods: Four hundred and one participants were included in this study. “Presence of TMD” in the participants was evaluated using the Fonseca Anamnestic Index. Through clinical examination, the findings in the participants were classified as limited mouth opening, deviation, temporomandibular joint (TMJ) sounds, TMJ pain, and muscle …

Case Report And X-Ray Microtomography And Scanning Electron Microscopy Analysis Of Teeth With Hypocalcified Amelogenesis Imperfecta, Rodrigo W. Marinoni, Thiago G. Silva, Leonardo S. Benato, Anelize M B Rumbelsperger, Antonio Adilson Soares De Lima

Journal of Dentistry Indonesia

Amelogenesis imperfecta (AI) is a genetic disease characterized by producing morphological and structural changes in tooth enamel. Objective: To highlight the morphological changes observed in teeth with hypocalcified AI based on scanning electron microscopy and microtomography analysis. Case report: An adult male had teeth seriously compromised by hypocalcified AI. The treatment plan involved removal of third molars followed by restorative and prosthetic treatment. After extraction, the teeth were analyzed by SEM and X-ray microtomography (microCT). Teeth with AI revealed the presence of microfractures arranged from the outer surface to the center of the enamel. Microfractures had a cracked or “cracked …