Digital Commons Network^™

The Investigation Of The Antimicrobial And Biofilm-Disrupting Properties Of Synthesized Hemibastadin Derivatives, Antonio Harvey, Andrew A. Yeagley

Longwood Senior Thesis Proposal

We want to investigate structural changes to the core hemibastadin structure while attempting to make these derivatives biologically safer. Since these modifications have never been done before, we will need to design a synthesis of these new molecules. Due to the nature of the molecules (dimers), a divergent synthesis that allows for the creation of both halves simultaneously seems most appropriate. A successful synthesis of these compounds will allow us to further investigate these derivatives for their antimicrobial and biofilm-disrupting properties.

The Concept Of Legal Subject Competence In The Authority To Act On Marriage Law In Indonesia, Imelda Martinelli, F.X. Joko Priyono, Yunanto Yunanto

Indonesia Law Review

This article focuses on discussing legal politics related to one important issue which is very basic, namely regarding the criteria for the ability to act of a human being as a legal subject within the scope of civil law, especially marriage law regarding the minimum age limit for entering into a marriage, who come from backgrounds with different interests and ideologies, make this an issue that can be highlighted. So the problem in this paper becomes whether there is a concept regarding the legal subject's competence in the authority to act on marriage law in Indonesia that accommodates the law …

Identification Of Scientific Argumentation Ability Of High School Students On Optical Instrument Material, Rais Muktamar Amin, Parno Parno, Sentot Kusairi, Marlina Ali

Jurnal Pendidikan Sains

Optical instruments play a crucial role in physics education, providing essential material for students to understand complex concepts. This study aims to evaluate the scientific argumentation abilities of high school students regarding optical instruments. Conducted as a quantitative descriptive study, the research involved 60 eleventh-grade MIPA students from SMA Laboratorium UM. The research instrument was a scientific argumentation test comprising 12 essay questions, designed according to the Toulmin Argumentation Pattern (TAP) adaptation indicators, with a reliability coefficient of 0.332. Student responses were classified into five levels of scientific argumentation based on the TAP model, as developed by Sampson, Enderle, and …

Identifying Students’ Incorrect Common-Sense Knowledge In Forces And Motion: Recommendations For Developing Computer-Based Learning Media, Ahmad Ridlotul Adha, Sutopo Sutopo, Nasikhuddin Nasikhuddin

Jurnal Pendidikan Sains

Conceptual understanding is a crucial area in physics education research, focusing on students’ comprehension of fundamental principles. Force and motion, integral topics within this field, are inherently linked to students’ daily experiences. Numerous studies have identified the persistence of common sense knowledge among students. This research presents a literature review aimed at identifying such consistently held misconceptions. We analyzed 17 papers sourced from Publish or Perish 8, Google Scholar, and Scopus. Our analysis revealed that the concepts of impetus and active force are the most persistent forms of common sense knowledge, influenced by real-life experiences. Additionally, students’ difficulties with kinematics …

Consequences Of Spatial Structure In Soil–Geomorphic Data On The Results Of Machine Learning Models, Daehyun Kim, Insang Song, Lorrayne Miralha, Daniel R. Hirmas, Ryan W. Mcewan, Tom G. Mueller, Pavel Samonil

Biology Faculty Publications

In this paper, we examined the degree to which inherent spatial structure in soil properties influences the outcomes of machine learning (ML) approaches to predicting soil spatial variability. We compared the performances of four ML algorithms (support vector machine, artificial neural network, random forest, and random forest for spatial data) against two non-ML algorithms (ordinary least squares regression and spatial filtering regression). None of the ML algorithms produced residuals that had lower mean values or were less autocorrelated over space compared with the non-ML approaches. We recommend the use of random forest when a soil variable of interest is weakly …

Governor's Office Of Diversity Business Enterprise (Go-Dbe) Annual Report 2023, Tennessee. Department Of General Services.

GO-DBE Report

No abstract provided.

Novel Anti-Influenza Monoclonal Antibodies, Ozlem Gurses

NYMC Student Theses and Dissertations

There is a continual public threat of influenza virus infections. This is related to viruses evolving in multiple animal reservoirs, making infection prevention in humans difficult to achieve and leading to seasonal epidemics and the semi-regular emergence of pandemics. Novel antibody-based therapies are of great interest to researchers because of a dramatic increase in drug resistant strains of influenza viruses. The identification of cross-reactive and broadly protective monoclonal antibodies targeting the influenza proteins presents a promising prospect for the development of a universal therapy. Although the research related to the monoclonal antibodies targeting the viral internal proteins is limited, multiple …

Risk Burden Of Heat-Related Morbidity Due To Urban Heat Island Effect In Tamalanrea District, Makassar, Angelia Khairunnisa, Ihsan Ihsan, Marly Patandianan

Media Kesehatan Masyarakat Indonesia

One of the problems in the urban environment is the rise in land surface temperature and heat buildup (Urban Heat Island) around built-up areas. People living in UHI areas will experience an increased risk of health burdens. Therefore, early identification for disaster mitigation is needed to achieve a sustainable city. This study aims to provide an overview of the risk of the spread of heat-related diseases based on the relative risk value in Tamalanrea District. This study considers the relationship between Land Surface Temperature (LST) values in 2019, 2020, and 2021 with the incidence of heat-related diseases obtained from the …

The Effect Of The Beruang Game On Symbolic Thinking Ability And Logical-Mathematical Intelligence, Alif Kurin’Ain, Hermanto Hermanto

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

Meneliti pengaruh permainan Beruang (Number Hunting) terhadap kemampuan berpikir simbolik dan kecerdasan logis-matematis anak PAUD. Hasil menunjukkan peningkatan signifikan pada kedua aspek dibanding kelompok kontrol.

Oer About Open Access: A Brief Assessment, Jill Cirasella

Publications and Research

This report provides an overview of the Open Access collection curated for the Scholarly Communication Notebook (SCN) Hub on OER Commons, as well as an assessment of the existing body of open educational resources (OER) about open access (OA).

Foundation Of Revolutionary Topologies: An Overview, Examples, Trend Analysis, Research Issues, Challenges, And Future Directions, Florentin Smarandache

Neutrosophic Systems with Applications

We now found nine new topologies, such as: NonStandard Topology, Largest Extended NonStandard Real Topology, Neutrosophic Triplet Weak/Strong Topologies, Neutrosophic Extended Triplet Weak/Strong Topologies, Neutrosophic Duplet Topology, Neutrosophic Extended Duplet Topology, Neutrosophic MultiSet Topology, and recall and improve the seven previously founded topologies in the years (2019-2023), namely: NonStandard Neutrosophic Topology, NeutroTopology, AntiTopology, Refined Neutrosophic Topology, Refined Neutrosophic Crisp Topology, SuperHyperTopology, and Neutrosophic SuperHyperTopology. They are called avantgarde topologies because of their innovative forms.

(De)Humanization Of Physically Disabled Bodies In Borderlands 3, Natasha Talitha Anindya, Lastiko Endi Rahmantyo

Paradigma: Jurnal Kajian Budaya

The video game industry has played a role in both affirming and erasing stereotypes surrounding minorities, especially those with disabilities. This study aims to analyse Borderlands 3’s in-game narrative that represents physically disabled characters through their characterization, visualization, and individual character development in the main plot campaign, illustrating how positive representation helps fight common stigmas and negative stereotypes. By using Shakespeare’s social model of disability as a theoretical framework, the analysis will view the game as text to identify physically disabled characters and determine if they face discrimination in the in-game universe. Results show that characters with prosthetics are considered …

A Digital Qualitative Ethnographic Study Of Preservice Teachers’ Perspectives And Experiences Of Teaching From To-Be Teachers, Mohamed Abdullahi Ali

Journal of Research Initiatives

This digital ethnographic study aimed to understand how and why college students decide to be teachers while many trained teachers leave the profession every year in the United States. A purposive sampling technique enabled 30 prospective teachers in a college of education to participate in this study. The research questions that guided the study were: 1) How and why did preservice teachers choose teaching as a career? 2) How did preservice teachers' perception of the drawbacks of teaching and the opportunities to support them in becoming teachers influence their decisions? The conceptual framework to understand the phenomena came from educational …

Disrupting Pedagogy: High School Students Making Sense Of The Flipped Learning Instructional Videos, Celeca A. Sukra

Journal of Research Initiatives

Technology has impacted every aspect of modern culture, including education. The influx of educational technology in schools presents opportunities to explore ways to engage students in the learning process fully. Although students may enjoy using technology in their daily lives, it is necessary to carefully consider how these students make sense of technology in the learning environment. Using the theoretical framework of constructivism, this Interpretative Phenomenological Analysis (IPA) aimed to understand and describe the lived experiences of three students using technology to learn in a flipped classroom at a New York City public charter high school. The significant findings reveal …

The Impact Of Teacher Preparedness And Professional Development On Fourth-Grade Students' Science Achievement, Craig L. Mayo, Faye Bradley

Journal of Research Initiatives

Science scores among US fourth-grade students have declined compared to their international counterparts in recent years. Recent results show that teachers are the most impactful influence on student success and accountability. Teacher preparedness and professional development are two key areas that serve as indicators of providing relevant and essential information for students' success. A correlational quantitative study was conducted to assess the relationship between teacher preparedness and professional development on fourth-grade students’ science achievement. The TIMSS 2019 data were secured from the Boston College, TIMSS, and PIRLS International websites. The data was evaluated using the SPSS 27 Hierarchical Linear Regression. …

Regulators Are Exploring With Industry How To Strengthen Quality Risk Management Practices, With Revision Of Ich Q9 A Key Focal Point, ( Ipq )

Level 3

No abstract provided.

Annual Report, 2022-2023, Cal Poly Humboldt Library

Library Publications

Dean's Welcome
Look Closer: 3D Digital Herbarium
Dive Deeper:Sustainable Library Certification
Chart The Way: Discovering Humboldt Project
Grow Here: Children's Collection
Find Creative Paths: Hackathon
Document Stories: the Press at Cal Poly Humboldt
Expand Experience: Student Employment
Create Community: Makerspace
Preserve the Past & Advance the Future: Special Collections
Exchange Far & Wide: Resource Sharing
Look Forward

Role Of Urban Parks In Carbon Sequestration– A Case Study Of Safari Park, Karachi, Pakistan, Amna Bano, Minzah Shehzad, Hasnain Kazmi, Jamshaid Iqbal

Journal of Bioresource Management

Urban parks besides their recreational use can be the potential source of climate mitigation through carbon sequestration. Present study aims to identify the carbon sequestration potential of Safari Park which is by far the largest public park of Karachi established in 1970 covering an area of 0.72 km². A total of 153 individual trees belonging to 25 species and 14 families were included in the study. Five dominant species with highest Important Value Index (IVI) were Cocos nucifera (14.62 %), Azadirachta indica (14.21 %), Guaiacum officinale (9.93 %), Washington robusta (9.31 %) and Delonix regia (7.11 %). The …

Smart Missions That Enable Innovation In High-Risk Environments., Ed Hoffman

Level 3

This article is a lightly edited version of Ed Hoffman’s talk on to the 01-June-2023 seminar hosted by the PRST entitled ICH Q9(R1): The Next Frontier – An audience with international thought leaders exploring how the effective use of knowledge can enhance QRM outcomes to benefit the patient. Ed’s remarks are focused on the future of work, and the needs for relationships, storytelling, and understanding the mission to get the best out of our collective intelligence and navigate the future of work.

Morning Panel Discussion, Alice Redmond, Aidan Harrington

Level 3

No abstract provided.

Introducing Research Collaboration And Gmp Human Resource Development At Three Universities With Gmp Laboratories In Japan, Shingou Sakurai, Osamu Hiruta, Ryoko Naruse

Level 3

This paper summarises initiatives presented on June 1^st 2023 at a seminar during a visit to Technological University Dublin. The authors travelled from 3 universities in Japan to share some of the collaborative research, education and training initiatives developed by them,

In their presentation the authors gave an overview of the current situation of Knowledge Management and Quality Culture in Japan, highlighting some recent issues and challenges, and presented some initiatives under development to specifically address these challenges.

Industry/Regulator Dialogue On Knowledge Management Is Intensifying In Wake Of Ich’S Q12 Initiative, ( Ipq )

Level 3

No abstract provided.

Analysis Of Community-Based Pattern Of Water Demand And Supply, Ishaku Dibal Joshua, Abdullahi Chado Salihu, Ayuba Musa Mshelia, Nchedo Nnedinma Ubachukwu

Journal of Environmental Science and Sustainable Development

Gombi rural community of Adamawa state, Nigeria, has witnessed significant growth in human population, which has contributed to an increase in water demand. Thus, the study analyzed water demand and supply patterns in Gombi communities of Adamawa State, Nigeria. A structured questionnaire was used for data collection. Descriptive statistics such as mean and percentages and inferential statistics like Analysis of Variance (ANOVA), chi-square, and linear regression were adopted for the analysis. The results on socioeconomic characteristics showed that the majority were females, with low household income levels, large household sizes, and in their active ages. Hand-dug well water was the …

Conversion Of Cellulose To 5-Hydroxymethylfurfural As Sustainable Energy: A Bibliometric Analysis By Vosviewer, Royyan Faradis, Ardiansyah Bagus Suryanto, Irmina Kris Murwani

Journal of Environmental Science and Sustainable Development

The developments of the global economy and society impact resources and the environment. This condition requires an alternative to find new, safe, and sustainable energy types. The conversion of cellulose to 5-hydroxymethylfurfural (5-HMF) has become a significant area of research interest. It has triggered the development of research directions related to biomass and energy because it can be an intermediary source for making polymers, solvents, pharmaceuticals, and biofuels. The primary objective of this study is to give a bibliometric analysis of 1753 reports on the development of research on cellulose conversion to 5-HMF from 1965 to 2021. The data were …

Assessing The Burden Of An Excessive Sms Size On The Effective Implementation Of The Ism Code, Li An Xian

World Maritime University Dissertations

No abstract provided.

A Peculiar Natural Wonderland Of South China Sea: A Bird’S Eye View, Mohamad Nor Azra, Mohd Iqbal Mohd Noor, Juneta-Nor Abu Seman, Lee Seong Wei Dr

Journal of Environmental Science and Sustainable Development

The South China Sea research agenda has increased over the years. However, no scientometric studies have been performed on this topic, which has helped analyze the research on the South China Sea throughout many years. Thus, this study aimed to investigate the global findings of previous research on the South China Sea, development trends, and trending issues surrounding the sea. Literature was extracted from the Web of Science Core Collection (WOSCC) database, and the CiteSpace software was used to visualize the data analyzed. The survey included 12,755 articles. Overall, the number of publications increased annually. Acta Oceanologica Sinica and the …

The Role Of Live Streaming In Building Consumer Trust, Engagement, And Purchase Intention In Indonesian Social Commerce Thrift Clothes Sellers, Amyra Salsabela Yasser, Gita Gayatri

ASEAN Marketing Journal

Manuscript type: Research Article

Research Aims: Examine the relationship between shopping values consumers perceive during live streaming and their trust, engagement, and intention to purchase from Indonesian social commerce thrift clothes sellers.

Design/methodology/approach: Data was gathered through an online survey from consumers who have watched a live-streaming session of an online thrift clothes shop on Instagram. Data were analysed using covariance-based Structural Equation Modelling (SEM).

Research Findings: The output shows that only the utilitarian value of live stream positively affects trust in products and sellers. The variable engagement was only significantly affected by hedonic value. Additionally, the only …

The Effect Of Social Media Brand Engagement On Customer Brand Loyalty: A Study On Skincare Brands Customers In Indonesia, Dodi Ria Atmaja, Riska Ware Arum Sari

ASEAN Marketing Journal

Abstract

Manuscript type: Research Paper

Research Aims: This research aims to examine the impact of brand engagement on social media on consumer brand loyalty (BL), by investigating the moderating roles of brand co-creation, brand trust, and brand experience variables.

Design/methodology/approach: The study employed a purposive sampling method, involving 230 respondents. The data was analyzed using Structural Equation Modeling (SEM).

Research Findings: The results show that brand experience can moderate the impact of brand co-creation (BCC) on brand loyalty (BL). However, social media brand engagement does not always have a direct impact on brand loyalty (BL), suggesting that other factors may …

Hotel Digital Capability: Dimensionality And Measurement, Lingling Fan, Chaowu Xie, Jiangchi Zhang, Songshan Huang, Xuequn Wang

Research outputs 2022 to 2026

While the significance of Hotel Digital Capability (HDC) has been acknowledged in the literature, limited attention has been given to its measurement. This study endeavors to identify the dimensions of HDC and construct a reliable measurement scale. A combined approach of qualitative and quantitative methods across three studies was employed to achieve the research objectives. Study 1, grounded in interviews, delineated HDC as a multidimensional construct encompassing digital basic capability, digital integration capability, digital application capability, and digital optimization capability. Building on the four-factor model identified in Study 1, Study 2 formulated an 18-item scale with robust measurement properties. Additionally, …

Covalent Inhibition Of Enzyme Sortase A As A New Pathway Against Bacterial Resistance Of Staphylococcus Aureus, Umyeena Bashir

Master's Theses

The continued rise of antibiotic-resistant bacteria, such as MRSA (methicillin-resistant Staphylococcus aureus), has made the discovery of novel antibiotics critical. While bacteriostatic and bactericidal antibiotics inevitably exert evolutionary pressure on bacteria to develop resistance, small molecules that target mechanisms of bacterial virulence present a promising alternative for treatment. Sortase A (Srt A), a cysteine protease of S. aureus, promotes bacterial virulence by covalently attaching proteins such as pilin to the bacterial surface, enabling bacterial adhesion to mammalian cells. Inhibitory studies of this enzyme have gained prominent interest as a new pathway for drug development since blocking this enzyme's ability to …