Digital Commons Network^™

Expanding The Omop Common Data Model To Support Extracorporeal Life Support Research, Clemens Rieder, Ahmed Said, Et Al.

2020-Current year OA Pubs

OBJECTIVE: Despite the increased availability of electronic health records, open-source standardized data collection to facilitate high-resolution data during extracorporeal life support (ECLS) is lacking. This project aimed to assess the Observational Medical Outcomes Partnership Common Data Model (OMOP CDM) for interoperability to store data sufficiently generated in the context of ECLS and to develop a custom data model expansion in case the OMOP CDM proved insufficient.

DESIGN AND SETTING: The OMOP CDM was analyzed qualitatively by expert consensus for its capability to capture data relative to ECLS as well as the presence of fitting ECLS-related concepts. Database entries necessary to …

Supramolecular Assembly In Short Peptide Systems For Selective Metabolite Recognition And Drug Nanoencapsulation, Maithreyi Ramakrishnan

Dissertations, Theses, and Capstone Projects

Short peptides can form adaptive supramolecular assemblies, and understanding how minimal sequences organize around neurometabolites or hydrophobic cancer drugs enables the rational design of functional materials. This thesis combines molecular dynamics with experimental validation to establish design rules linking peptide sequence to emergent structure and function. Chapter 1 outlines the molecular determinants governing peptide assembly. Chapter 2 reviews computational workflows that reveal sequence-dependent conformations and supramolecular organization. Chapter 3 applies these principles to Dynamic Peptide Libraries which identify tetrapeptides that selectively interact with neurometabolites. Chapter 4 extends the same interaction-driven framework to design tryptophan-rich pentapeptides that co-assemble with kinase inhibitors …

Managing Migration And Political Change: Lessons From Sweden’S 2015 Asylum Crisis For South Korea’S Emerging Immigration Era, Sean Lee

Dissertations, Theses, and Capstone Projects

The purpose of this capstone project is to analyze how two nations that have little in common in terms of geography or politics have been required to deal with immigration issues in ways that their institutions did not anticipate. One nation has been dealing with immigration-related issues for some time now, while the other nation has yet to do so. In 2015, when Sweden received approximately 162,000 asylum applications in one year alone, Sweden’s housing systems were strained, many of the municipalities were unable to keep up with the demand, and the political climate began to shift in ways that …

Radiotheranostics For Gynecological Pathologies, Joni Sebastiano

Dissertations, Theses, and Capstone Projects

Molecular imaging, specifically positron emission tomography (PET), is vital for detecting disease and understanding its biological makeup. The exploitation of radiolabeled antibodies for PET imaging has proven to be indispensable to the field of molecular imaging over the last several decades. The development of radioimmunoconjugates for use in immunoPET has not only allowed for the sensitive, specific, and high-resolution detection of disease, but has also enabled a deeper understanding of the disease biology, ultimately guiding more personalized therapeutic strategies. Most typically, this technology is harnessed for the diagnosis and treatment of cancer, however more recently, the field has explored the …

Mediating Energy And Charge Transfer Dynamics Of Lead Halide Perovskite Nanocrystals Via Surface Chemical Approaches, Aaron S. Malinoski

Dissertations, Theses, and Capstone Projects

Energy and charge transfer are the fundamental mechanisms by which semiconductor nanocrystals interact with their external environment and underpin all light-conversion related applications. Lead halide perovskite nanocrystals (PNCs) are a relatively new class of semiconductor nanocrystals that possess a unique and dynamic surface chemical environment. Investigations into the influence of these surface chemical conditions on the electronic coupling between surface-bound molecular acceptors and the perovskite nanocrystals, and how the surface chemistry can be manipulated, in turn controlling the charge and energy transfer mechanisms, is the focus of this dissertation. Through ligand-shell engineering using commercially available, inexpensive small molecules, the surface …

Access Denied: Financial Aid Inequalities And The Economic Impact On Daca Students, Teresa D. Jordan

Dissertations, Theses, and Capstone Projects

This capstone project argues that financial aid policies in the United States create a system of structural inequality that systematically denies Deferred Action for Childhood Arrivals (DACA) recipients’ equitable access to higher education. Drawing on peer-reviewed scholarship, federal policy data, and large-scale survey research, this paper demonstrates how the categorical exclusion from federal financial aid, inconsistent in-state tuition laws, and recurring DACA renewal fees form an interlocking barrier with profound psychological and economic consequences for a population that is deeply integrated into American society. These compounding barriers force students into a framework of constrained rationality, distorting their academic major choices …

Computational Insights Into Nucleosome Dynamics In Epigenetics Using Molecular Dynamics Simulations, Rutika Patel

Dissertations, Theses, and Capstone Projects

Nucleosome core particles (NCP) are the building blocks that form a highly organized and compact chromatin structure. Nucleosomes package DNA in the nucleus of eukaryotic cells. The NCP consists of about 147 base pairs of DNA wrapped around the histone octamer, with 1.65 superhelical turns in a left-handed manner. The histone octamer is composed of two copies of H3, H4, H2A, and H2B. Together with histone H1 and linker DNA, they further assemble into a higher-order chromatin structure. The nucleosome complex is stabilized by electrostatic interactions between positively charged histone residues and the negatively charged DNA backbone. To effectively access …

Enhancing Ecological Validity In Speech-In-Noise Testing: Integrating Virtual Reality For A Multisensory Audiological Experience, Paulina Lee

Dissertations, Theses, and Capstone Projects

Despite the remarkable advances in hearing healthcare technology, the speech recognition tests used in routine clinical audiological assessment have remained essentially the same for decades.  Monosyllabic word recognition tests in quiet, such as the Northwestern University Auditory Test No. 6 (NU-6; Tillman & Carhart, 1966), have served as the audiology field’s default measure of speech understanding.  Modern speech-in-noise (SIN) tests, such as the QuickSIN (Killion et al., 2004), have emerged, yet they remain auditory-only, leaving an unignorable gap between what clinical tests measure and how patients communicate in daily life.  The present study examined whether pairing a standard SIN test …

A Comparison Of Manufacturers’ Claims Of Attenuation Rates In Non-Custom Earplugs, Skyler M. Shipley

Dissertations, Theses, and Capstone Projects

Recreational and social environments frequently expose individuals to high intensity noise environments; however, the use of hearing protection devices (HPDs) remains limited. This study evaluated whether non-custom, over-the-counter musicians’ earplugs provide attenuation consistent with manufacturers’ claims and whether cost is associated with performance. Six commercially available earplug models were tested using both human participants and a KEMAR manikin system. Attenuation was measured across frequencies from 250–8000 Hz (octave and inter-octave frequencies) and were tested using different ear tip sizes. Results indicated that several earplugs achieved attenuation levels comparable to or exceeding their advertised noise reduction ratings (NRR), though consistency varied …

Measuring Islamic Republic Propaganda In Western Media Coverage Of Iran: A Computational Framework, Leila Habibi

Dissertations, Theses, and Capstone Projects

Detecting propaganda is fundamentally difficult: effective propaganda must simultaneously conceal persuasive intent while achieving persuasive effect, which means that sophisticated propagandistic discourse necessarily occupies the ambiguous middle of a rhetorical spectrum rather than its obvious extremes. This thesis defines this property as the dual constraint problem and argues that it poses two challenges for the binary classification framing that dominates propaganda detection in Natural Language Processing (NLP). First, propaganda by definition does not come with clear labels: no propaganda arm willingly accepts the designation, so reliable ground truth does not exist at the source. Second, because the producer is actively …

Gramsci’S ‘Democratic Philosopher’ And The Concept’S Foundations In Marxian Social Ontology, Eli Recht-Appel

Dissertations, Theses, and Capstone Projects

This thesis deals with the term ‘democratic philosopher’ from Antonio Gramsci’s Prison Notebooks. In order to lay the groundwork for my distinct interpretation of the ‘democratic philosopher,’ I begin by providing an overview of Gramsci’s theory of the role of intellectuals in civil and political society. I then argue that the ‘democratic philosopher’ emerges from Gramsci’s typology of intellectuals but is a category which is both temporally and ontologically distinct from his more well-known concept of ‘organic intellectuals.’ ‘Organic intellectuals,’ intellectuals who co-develop alongside their fundamental social group or class, occupy a variety of cultural and political roles in …

Semi-Peripheral Whiteness In A Global City: Central And Eastern European Women In Dubai, Hana Rubenstein

Dissertations, Theses, and Capstone Projects

This capstone examines how Central and Eastern European (CEE) women navigate professional mobility in Dubai and asks to what extent Dubai enables them to bypass the post-socialist stigma attached to their semi-peripheral European identity. Situated at the intersection of migration studies, gender, and critical scholarship on semi-peripheral whiteness, the study addresses the limited attention paid to CEE women as economic actors outside European contexts, where they are often either absorbed into the category of “Western expatriates” or reduced to highly gendered stereotypes. Grounded in a qualitative, interpretivist approach, the study combines digital discourse analysis of 50 publicly accessible LinkedIn profiles …

Gremlin Theory: A Film Art Of Joe Dante, Frank Falisi

Dissertations, Theses, and Capstone Projects

This thesis seeks to establish the work of the filmmaker Joe Dante as a catalyzing and anarchic force let loose inside larger, dumber superstructures: linear narrativity, Hollywood, America, etc. It works to read the genre films he worked on—many of them made as popular entertainment for mainstream movie studios—as moments of actual subversion, allocating status quo (studio system) resources to create a biting-back against American imperial norms in the lingua franca of Marx and the Marx Brothers: gummy leisure-seeking stupidity and Gremlin transformation. This thesis seeks to argue that to understand Dante’s work is to understand pop transfiguration itself. This …

Wageless By Design: Dependency In U.S. Visa Regimes, Cristina Ochoa Echeverri

Dissertations, Theses, and Capstone Projects

This capstone examines how U.S. dependent visa regimes create a population of migrants who are legally present but structurally excluded from paid work and independent legal status. Focusing on visa categories such as H-4, F-2, M-2, O-3, P-4, R-2, and TD, it argues that wagelessness is not incidental but structurally embedded in the legal design of temporary migration governance through employment restrictions, derivative legal status, and the tethering of dependents to a principal visa holder.

Using a qualitative, interpretive approach, this study draws on documentary and secondary sources as well as digital narratives from platforms such as Reddit. This capstone …

Electromagnetic Counterparts To Active Galactic Nucleus Disk-Embedded Binary Black Hole Mergers, Emily Mcpike

Dissertations, Theses, and Capstone Projects

The accretion disks of active galactic nuclei (AGN) are promising environments for producing binary black hole (BBH) mergers, which have been detected via gravitational waves (GW) with LIGO-Virgo-KAGRA (LVK). BBH mergers embedded in AGN disks are unique among GW formation channels in their generic ability to produce electromagnetic (EM) counterparts, via interactions between the merger remnant and the surrounding disk gas (though these are not always observable). While such mergers represent valuable multi-messenger sources, the lack of predictive statistical models in existing literature currently limits our ability to select possible EM counterparts with GW detections in archival data and in …

Variational Methods For Semilinear Pdes With Dirac Singularities, Samuel J. Magill

Dissertations, Theses, and Capstone Projects

This dissertation utilizes a variational framework for semilinear elliptic equations in two dimensions with Dirac measure data. The central objects of study are equations of the form −ΔU = f(U) + Σ_j=1^N α_jδ_pj on bounded Lipschitz domains Ω ⊂ ℝ² with homogeneous Dirichlet boundary condition, and on a flat torus 𝕋², where α_j is positive for the Dirichlet setting and α_j is negative on the torus. Solutions are obtained by minimizing the restriction of an energy functional to an order interval determined by explicit sub- and supersolutions; the Euler–Lagrange equation is recovered …

Considering Numerical Relativity For Upgrades In Mcfacts Merger Dynamics, Shawn K. Ray

Dissertations, Theses, and Capstone Projects

Binary black hole mergers (BBH), some likely originating from active galactic nuclei (AGN), are observed by ground-based detectors such as LIGO-Virgo-KAGRA (LVK) and will be detected by future space-based detectors such as the Laser Interferometer Space Antenna (LISA) and the Laser Interferometer Lunar Antenna (LILA). The dynamics of AGN may be responsible for a significant fraction of BBH mergers soon to be observed by LISA and LILA, yet the dynamics of BBH mergers within AGN disks remains ambiguous despite their appearance in gravitational wave observations. Monte carlo For AGN Channel Testing and Simulation (McFACTS) is an open-source software used to …

A Data Analysis Study Of Temperature Based On California Cooperative Oceanic Fisheries Investigations (Calcofi) Data., Afsana Mimi

Dissertations, Theses, and Capstone Projects

This research presents an integrated analytical framework for predicting ocean temperatures using long-term observations from the California Cooperative Oceanic Fisheries Investigations (CalCOFI) data files. The study applies advanced data engineering and statistical modeling to assess how a variety of indicators, such as salinity, dissolved oxygen, key nutrients, and ocean depth shape oceanic temperature patterns along the California coastline. Using Microsoft SQL Server software for large-scale data integration and the R for statistical packages (R Core Team, 2025) for statistical computation, I developed and compared multiple regression models, including the ridge regression model, to evaluate the relative influence of physical and …

Theatrical Agency In The Constitution Of Logical Space, Esther Marveta Neff

Dissertations, Theses, and Capstone Projects

This dissertation takes advantage of our current moment of collapse and shifting episteme to move from resistance and critique into modes of position, prefiguration, and praxiocentricism, giving not only a critique of the colonial-modern logical space of Theatrum Mundi, but also aiming to configure the thetic consciousness that grounds “theatrical agency” in the logic of cognitive and social epistemological modelling.  In what ways do we “build our own worlds”? What does “theatricality” tell us about human agency, especially in the domain of “theoretical attitudes,” and “consciousness”? In what ways, and to what extent, are we responsible for constituting …

Inductive Biases In Field-Level Cosmological Inference From Galaxy Catalogs, James O'Connor Baldwin

Dissertations, Theses, and Capstone Projects

We perform field-level likelihood-free inference of the matter density parameter Ωm from simulated galaxy catalogs using machine learning models with differing inductive biases. Using features extracted from hydrodynamic simulations in the CAMELS suite, we investigate how both observable choice and model architecture govern the extraction of cosmological information. We consider galaxy positions and line-of-sight peculiar velocities, both separately and in combination, and compare permutation-invariant Deep Sets, implemented with either standard multilayer perceptrons (MLPs) or Kolmogorov–Arnold Networks (KANs), to graph neural networks (GNNs) implemented with MLPs, which explicitly encode spatial relations. We evaluate inference performance under both in-distribution and out-of-distribution (OOD) …

Immunomodulatory And Signaling Molecules From Plant-Associated Bacteria: Toll-Like Receptor 4 Agonist Adjuvants And Diketopiperazine-Mediated Communication, Marian Romaine

Dissertations, Theses, and Capstone Projects

Medicinal plants and their associated microbiomes constitute a rich source of bioactive natural products with applications in immunotherapy and microbial ecology. Herbal formulations have long been valued for safe immune enhancement, while bacterial signaling molecules govern community behaviors critical to pathogenesis, symbiosis, and environmental processes. Bacterial lipopolysaccharides (LPS) from plant-associated Gram-negative bacteria have emerged as potent TLR4 agonists, yet their endotoxic potential limits direct use, and diketopiperazines (DKPs) serve as versatile quorum-sensing mediators capable of modulating biofilms in mixed microbial systems.

The work in this thesis comprises two independent but complementary research strands. The first strand pursued the engineering of …

Vestigial Choreographies: Climate Consciousness In The Long Nineteenth Century, Alexandra A. Rego

Dissertations, Theses, and Capstone Projects

The aims of this project are twofold: (a) to develop a method of theoretical analysis and (b) to put this method into pointed use. In service of (a), I propose a method of choreographic analysis. This method operates relationally, highlighting the production of movement and stillness among and between bodies, objects, and encounters. Choreographic analysis draws from methods typically sequestered to dance studies. Towards aim (b), this project demonstrates the relevance and breadth of choreographic analysis by connecting it to ecocriticism. Throughout this project, I apply choreographic analysis to a diverse set of case studies. I use choreographic analysis to …

Neuroenvironmental Footprint: Integrating Air Quality Into Neuroarchitectural Research In Educational Spaces, María Beltrán Rodríguez, Ivette Caldelas

Congresos y Conferencias

Environmental quality is widely recognised as one of the most decisive factors in public health. Its relevance is particularly critical in the case of children, as it directly affects both their physical and cognitive development. Indeed, different researches showed how the exposure to inadequate environmental conditions during early life stages may compromise health outcomes, learning capacity, and overall well-being. Consequently, improving environmental quality in educational settings is not only a matter of comfort, but an essential public health priority. In this context, the International Symposium of Environmental Quality in Educational Spaces (inSiEqES) emerges as a necessary initiative to foster dialogue, …

Toward Data-Centric Ai: A Comprehensive Survey Of Traditional, Reinforcement, And Generative Approaches For Tabular Data Transformation, Dongjie Wang, Yanyong Huang, Wangyang Ying, Haoyue Bai, Nanxu Gong, Xinyuan Wang, Sixun Dong, Tao Zhe, Kunpeng Liu, Meng Xiao, Multiple Additional Authors

Computer Science Faculty Publications and Presentations

Tabular data is one of the most widely used formats across industries, driving critical applications in areas such as finance, healthcare, and marketing. In the era of data-centric AI, improving data quality and representation has become essential for enhancing model performance, particularly in applications centered around tabular data. This survey examines the key aspects of tabular data-centric AI, emphasizing feature selection and feature generation as essential techniques for data space refinement. We provide a systematic review of feature selection methods, which identify and retain the most relevant data attributes, and feature generation approaches, which create new features to simplify the …

Understanding Formal Financial Access In Indonesia: Evidence From Micro Data, M. Aulia Rachman, Yozi Aulia Rahman, Maulida Dewi Pangestika, Risanda Alirastra Budiantoro

Economics and Finance in Indonesia

This study examines the determinants of access to formal financial institutions using secondary household survey data from Indonesian Family Life Survey, Wave 5 (IFLS-5). Logistic regression analysis reveals that loan amount, savings, education level, age, housing status, and internet usage are positively and significantly associated with greater access. Individuals with higher savings, higher education, and homeownership exhibit a higher probability of utilizing formal financial services. Although the significance of internet usage varies across models, it remains a strong predictor when properly controlled, particularly due to its role in enhancing digital literacy. In contrast, income and health insurance ownership do not …

Biomedgraphica: An All-In-One Platform For Joint Textual Biomedical Prior Knowledge And Numeric Graph Generation, Heming Zhang, Shunning Liang, Tim Xu, Wenyu Li, Di Huang, Yuhan Dong, Philip Miller, Peter Goedegebuure, Marco Sardiello, Jonathan Cooper, William Buchser, Patricia Dickson, Ryan C Fields, Carlos Cruchaga, Yixin Chen, Michael Province, Philip Payne, Fuhai Li, Et Al.

2020-Current year OA Pubs

MOTIVATION: Multiomics data analysis is essential for scientific discovery in precision medicine. However, translating analysis results of omics data analysis into novel scientific hypotheses remains a significant challenge. Human experts must manually review analysis results and generate new hypotheses based on extensive and interconnected biomedical prior knowledge, which is subjective and not scalable. While large language models can accelerate the discovery, their reasoning improves when grounded in structured, auditable, and comprehensive biomedical prior knowledge. However, biomedical knowledge is scattered across heterogeneous databases that use diverse and inconsistent nomenclature systems, making it difficult to integrate resources into a unified format for …

Public Attitudes Toward Cascade Genetic Screening In The United States, Hadley Stevens Smith, Emilie S Zoltick, Madison R Hickingbotham, Emily S Bonkowski, Stacey Pereira, Tara A Lavelle, David L Veenstra, Amy L Mcguire, Katherine E Bonini, Leila Jamal

Center for Medical Ethics and Health Policy Staff Publications

Introduction: After a patient receives genetic test results that indicate an actionable health condition, cascade genetic screening (CGS) is the process of evaluating the patient's relatives for a potentially elevated genetic risk of disease. The United States primarily relies on patients to communicate with their relatives, resulting in suboptimal rates of risk communication, familial genetic testing uptake, and risk-reducing interventions. There is ongoing debate about whether and how best to inform relatives of a potentially increased genetic risk.

Methods: We conducted a nationally representative survey of US adults to assess attitudes toward informing at-risk relatives, acceptability of system-mediated communication, and …

Building On Rented Land: An Interpretive Phenomenological Analysis Of Black Women’S Digital Homeplace-Building On Tiktok, Monica Thompson

Dissertations, Theses, and Capstone Projects

This interpretative phenomenological analysis (IPA) examined the lived experiences of seven Black women TikTok users, exploring how they describe and make meaning of TikTok as a space of digital expression amid algorithmic constraint and platform precarity. Grounded in Black Cyberfeminism, Critical Race Theory, and hooks’ (1990) homeplace theory, the study asked three questions: how Black women describe their use of TikTok; how they make meaning of the platform as a space of expression; and how they navigate platform instability, political threats, and content restrictions while maintaining authentic expression. Drawing on semi-structured Zoom interviews and analyzed using Smith et al.’s (2009) …

Reexamining The Croton Aqueduct: A Ward-Level Microhistorical Analysis Of Infrastructure And Cholera Mortality In 1849 New York City, Alexandria R. Toothman

Dissertations, Theses, and Capstone Projects

This work reexamines the Croton Aqueduct’s role in public health by shifting analysis from the citywide level to the ward level, revealing that infrastructure expansion did not produce uniform benefits across New York City. When the Croton Aqueduct opened in 1842, it was celebrated as an achievement that would deliver pure water and eliminate disease. However, only seven years after its opening, in 1849, cholera returned with greater force in the Sixth Ward. This work shows that the uneven distribution of Croton infrastructure corresponded with uneven cholera mortality rates, challenging narratives that present Croton as a singular triumph of urban …

Materializing The Interface: Personal Data Feeds Generative Art, Erin Livingston

Dissertations, Theses, and Capstone Projects

Materializing the Interface: Personal Data Feeds Generative Art is a data-studio capstone project that reconstructs elements of desktop and mobile interfaces as handmade mixed-media artifacts, then digitizes them as an interactive website where generative text and images are fed by personal data flows. Twenty-one paper collage windows — built from cardstock, risograph-printed paper, and mixed media — were photographed, digitized, and activated using code to become the interactive surface of a desktop view driven by browser history. A corresponding mobile view renders a corpus of 500 Instagram advertisement screenshots through a risograph print aesthetic, fed by a hand-tagged emotion and …