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The First Transcriptomic Atlas Of The Adult Lacrimal Gland Reveals Epithelial Complexity And Identifies Novel Progenitor Cells In Mice, Anastasiia Ivanova, Takeshi Umazume, Sarah M Knox, Cintia S De Paiva, Darlene A Dartt, Helen P Makarenkova May 2023

The First Transcriptomic Atlas Of The Adult Lacrimal Gland Reveals Epithelial Complexity And Identifies Novel Progenitor Cells In Mice, Anastasiia Ivanova, Takeshi Umazume, Sarah M Knox, Cintia S De Paiva, Darlene A Dartt, Helen P Makarenkova

Faculty, Staff and Students Publications

The lacrimal gland (LG) secretes aqueous tears. Previous studies have provided insights into the cell lineage relationships during tissue morphogenesis. However, little is known about the cell types composing the adult LG and their progenitors. Using scRNAseq, we established the first comprehensive cell atlas of the adult mouse LG to investigate the cell hierarchy, its secretory repertoire, and the sex differences. Our analysis uncovered the complexity of the stromal landscape. Epithelium subclustering revealed myoepithelial cells, acinar subsets, and two novel acinar subpopulations: Tfrchi and Car6hi cells. The ductal compartment contained Wfdc2+ multilayered ducts and an Ltf+ cluster formed …


Impact Of Long-Term Trauma Exposure On Competitiveness And Generosity, Anchal Khandelwal May 2023

Impact Of Long-Term Trauma Exposure On Competitiveness And Generosity, Anchal Khandelwal

Master's Theses

: Although half of all nations in the world have experienced armed conflict in the last 50 years, there is still a glaring lack of evidence on the persistent human costs of these conflicts. We exploit the quasi-random variation in abduction (Blattman and Annan 2009) and establish a control (neighboring) sub-county based on the intensity of exposure by the Lord’s Resistance Army in Northern Uganda to investigate the long-term impact of trauma exposure on competitiveness and generosity. We do this by conducting lab-in-field experiments on a sample of adult North Ugandan women and find that trauma exposure reduces competitiveness in …


Definition And Characteristic Features Of A ‘Cultural Flashpoint’: A Case Study Of Exploring Masculinities, A Controversial Gender And Education Programme In Ireland, Joan Hanafin, Paul Conway, Cormac O Beaglaoich, Jack Hanafin May 2023

Definition And Characteristic Features Of A ‘Cultural Flashpoint’: A Case Study Of Exploring Masculinities, A Controversial Gender And Education Programme In Ireland, Joan Hanafin, Paul Conway, Cormac O Beaglaoich, Jack Hanafin

Articles

The concept ‘cultural flashpoint’ (CF) has not been fully defined or described. The authors test this concept through the prism of a controversial gender-focused Irish school programme, Exploring Masculinities (EM). Adopting an instrumental case study methodology, they use media content analysis to develop a temporal trajectory of the CF, describe its shape, explicit and implied contentious themes, and its process. They identify characteristic features of a cultural flashpoint: (i) a focal issue, event and/or object; (ii) conflict; (iii) bounded time period; (iv) the involvement of exo- and multi-sectoral individuals and groups; (v) randomness, opaqueness and conflation among its expressions; and …


Facilitators And Barriers To Effective Scale-Up Of Evidence-Based Nonprofit-Level Hiv Prevention And Treatment Interventions Among Black Men Who Have Sex With Men (Msm), Ugochukwu C. Uzoeghelu May 2023

Facilitators And Barriers To Effective Scale-Up Of Evidence-Based Nonprofit-Level Hiv Prevention And Treatment Interventions Among Black Men Who Have Sex With Men (Msm), Ugochukwu C. Uzoeghelu

Master's Projects and Capstones

Since the scale-up of HIV/AIDS prevention evidence-based interventions (EBIs) has not been simple in nonprofit settings, it is crucial to examine processes that occur in the translation of the EBIs into practice that affect successful implementation through the lens of nonprofit principles and practices. This paper examines the facilitators and barriers to effective scale-up of evidence-based HIV prevention and treatment services for nonprofit health organizations that serve Black men who have sex with men (MSM). I interviewed nonprofit health organizations (n = 4) engaged in the global response to end the HIV epidemic, specifically those who provide HIV prevention and …


Investment Without Displacement: A Study Of The Better Neighborhoods, Same Neighbors Initiative In East Oakland, Jeremy Mack May 2023

Investment Without Displacement: A Study Of The Better Neighborhoods, Same Neighbors Initiative In East Oakland, Jeremy Mack

Master's Projects and Capstones

This Capstone interrogates the teleology of neoliberal community development – does investment in historically disinvested working-class urban neighborhoods inevitably lead to gentrification? Learning from the Better Neighborhoods, Same Neighbors Initiative (BNSN) in Deep East Oakland as a case study, the Capstone uses a Transformative Justice (TJ) framework to make the case for an ethical approach to community development: one in which working-class urban residents are the authors and architects of their own neighborhood’s future, community needs are centered, and long-term residents are able to continue to age-in place. This approach utilizes the lens of Black-centered community development, integrating an understanding …


Recovering Vitality After Trauma Through The Use Of Body-Oriented Expressive Arts Therapy: A Literature Review, Kate Hall May 2023

Recovering Vitality After Trauma Through The Use Of Body-Oriented Expressive Arts Therapy: A Literature Review, Kate Hall

Expressive Therapies Capstone Theses

This capstone thesis examines how to use body-oriented expressive arts therapy to address dissociative symptoms of trauma in adults. Dissociation can arise during or after trauma has occurred and creates a state of disconnection in the body, inhibiting one’s sense of vitality. In this literature review, I provide a basis for why to look to the expressive arts and the body as effective resources for restoring vitality. I present relevant research on trauma, dissociation, and body-oriented expressive arts therapy; I also explore how concepts embedded in sensuality, pleasure, and eroticism may help inform how to use expressive arts therapy as …


Grief Web, Patricia M. Fong May 2023

Grief Web, Patricia M. Fong

Honors Projects

The grief web project is an attempt to respond to death. To become responseable — responsible and able to respond — within the deathzone: where the living and the dying meet, where we live on after they die, where their deaths make our lives possible. I grieve for all beings who have been made ungrievable, for all who die before their time, for all our dead and dying kin and kin of kin. In particular, I mourn for childhood friends who have been killed in my neighborhood, for species made extinct by climate change and capitalism, for my three grandmothers …


Conflict And Coltan: Resource Extraction And Collision In The Democratic Republic Of The Congo And Venezuela, Jenna Marie Goldblatt May 2023

Conflict And Coltan: Resource Extraction And Collision In The Democratic Republic Of The Congo And Venezuela, Jenna Marie Goldblatt

Senior Theses

Resource extraction has played an essential role in shaping human development and is an essential tool for technological improvement. However, resource extraction is also inherently exploitative of the environment, and therefore of people. This paper evaluates the relationship between Coltan, a mineral necessary for the creation of electronic capacitors, and the conflict it creates locally, regionally, and internationally through the case studies of the Democratic Republic of the Congo (DRC) and Venezuela. These case studies illustrate the relationship between export and consumption based countries and how this relationship keeps “developing” countries in a never ending cycle of development, and developed …


Immigration Policy After Covid-19 And Cultural Resistance At The U.S.-Mexico Border, Grace Ayres-Doyle May 2023

Immigration Policy After Covid-19 And Cultural Resistance At The U.S.-Mexico Border, Grace Ayres-Doyle

Senior Theses

What I examine here is how the global COVID-19 pandemic altered asylum and refugee responsibility among Global North countries. In particular, I look at cultural responses to restrictive pandemic policies which speak to the level of intensity of the current humanitarian crisis at the United States southern border with Mexico. The US-Mexico border functions well as a case study because of its highly publicized and discussed nature, along with the strong influence held by the US over the rest of the world. The cultural moment surrounding Title 42 and other pandemic policies represents a shift in public recognition of the …


The Politics Of Abortion In France And The United States: A Case Study On The Laws, Legislation, Activism, And Advocacy That Determined Abortion Laws Today, Annick Marie Strebin May 2023

The Politics Of Abortion In France And The United States: A Case Study On The Laws, Legislation, Activism, And Advocacy That Determined Abortion Laws Today, Annick Marie Strebin

Senior Theses

Abortion is one of the most pertinent issues to women’s health and reproductive rights. This paper aims first to provide the historical and legal context for abortion laws in both France and the United States, examining each country separately to understand the legal progression of abortion rights since the nineteenth century. This paper will then discuss the activism and advocacy for abortion and women’s rights in each country from the nineteenth century on, demonstrating how this led to the passing of abortion rights legislation in each country. Lastly, this paper will focus on differences in politics, religion, women’s rights, and …


Weaponization Of Religion: The Manipulation Of Religion In The Pursuit Of Political Power In Yugoslavia And Syria, Kathryn Echele May 2023

Weaponization Of Religion: The Manipulation Of Religion In The Pursuit Of Political Power In Yugoslavia And Syria, Kathryn Echele

Senior Theses

Religious conflict has played an important role in shaping human history, particularly in the last few decades with the proliferation of ethno-religious violence. This paper examines the development of the relationship between religion and politics, then analyzes how leaders manipulate religion to gain political power. Two case studies—Yugoslavia/Yugoslav Wars and Syria/Syrian Civil War—are used to demonstrate this ability religion has to spur conflict when coopted for political means. Yugoslavia and Syria make ideal case studies because both countries have a deeply rooted and seemingly inseparable link between ethnicity and religion. Methods of cooptation include using religious mythology and symbolism, influencing …


Advancing United Nation’S Gender Mainstreaming: Female Peacekeepers In Haiti And Liberia, Evening S. Huddleston May 2023

Advancing United Nation’S Gender Mainstreaming: Female Peacekeepers In Haiti And Liberia, Evening S. Huddleston

Senior Theses

The United Nations (UN) is making efforts to implement a gender mainstreaming perspective throughout its organization, specifically including women in the peace processes. One aspect of this is increasing the number of female peacekeepers. To determine the success of these efforts, this paper explores whether the lives of women and girls were improved during UN peacekeeping missions in Haiti and Liberia. Using women’s and girls’ participation in education, law enforcement, and politics, as well as the Gender Development Index and the Gender Inequality Index, this paper finds that including women in peacekeeping roles adds a new dimension of skills and …


Education And Welfare: Their Impact On The Experience Of Poverty In India And The United States, Anushka Rajani May 2023

Education And Welfare: Their Impact On The Experience Of Poverty In India And The United States, Anushka Rajani

Senior Theses

The experience of poverty and chances of upward mobility is drastically different in India and the United States. The following thesis contends that this is largely due to the current educational and welfare policies in place in these two nations. Education allows for a higher possibility of financial upward mobility by allowing students to learn skills that prepare them for higher-paying career paths. High-quality welfare gives recipients aid for their necessities while providing them time for growth to pursue financial independence. The following thesis investigates these policies and how accessible they make education and welfare to poor populations in India …


Watering The Grassroots: The Importance Of A Comprehensive Approach To Conflict In The Sahel, Chanelle A. Dortch May 2023

Watering The Grassroots: The Importance Of A Comprehensive Approach To Conflict In The Sahel, Chanelle A. Dortch

Senior Theses

The withdrawal of French troops from Mali in August 2021 has revealed massive structural problems with crisis intervention and conflict mitigation in Africa. The purpose of this research is to reveal how foreign intervention in the Sahel has failed to stabilize the region in the face of mounting political, socioeconomic, and environmental crises. This paper examines Mali and France, two countries that are centered in crisis in the Sahel, and how the politics of intervention have resulted in the current situation. While the crisis in the Sahel does not yet have a clear result, this project seeks to contextualize current …


Trapped In The Margins: Russia, The United Nations High Commissioner For Refugees, And The Story Of Afghan Refugees In Tajikistan, Meredith Schutt May 2023

Trapped In The Margins: Russia, The United Nations High Commissioner For Refugees, And The Story Of Afghan Refugees In Tajikistan, Meredith Schutt

Senior Theses

Since the Taliban’s return to Afghanistan, thousands of Afghans have fled the country in search of refugee status abroad. In the wake of this crisis, one country in the region, Tajikistan, opened its borders to Afghans, vowing to grant refugee status to 100,000. Today, Tajikistan has closed its borders and is forcibly returning Afghan refugees and asylum seekers. This research aims to reveal the extent of influence that external parties have on Afghan refugee flows in Tajikistan. For this paper, the two external parties examined are the United Nations High Commissioner for Refugees (UNHCR) and Russia. In examining the role …


The Relationship Between Instructed Non-Immersion Additional Language (Lx) Learning And Student Outcomes Of Diversity-Equity-Inclusion (Dei)-Focused Education For U.S. High School Students, Congmin Zhao May 2023

The Relationship Between Instructed Non-Immersion Additional Language (Lx) Learning And Student Outcomes Of Diversity-Equity-Inclusion (Dei)-Focused Education For U.S. High School Students, Congmin Zhao

Educational Studies Dissertations

Research has found that teaching about diversity, equity, and inclusion (DEI) can raise U.S. high school students’ awareness about DEI-related topics and develop their critical thinking skills to analyze DEI-related issues. But the achievements of DEI-focused education are limited. Thus, DEI-focused education needs complementary efforts to enhance student outcomes. Research has also found that learning an additional language (LX) may heighten students’ interest in learning about other cultural communities, nurture students’ cross-cultural empathy, and elicit culturally responsive behaviors. The juxtaposition of these findings signifies the potential for LX learning to complement DEI-focused education to improve learning outcomes. However, the value …


Re-Storying Teaching: Using Narradrama To Address Burnout In Public School Teachers, Heather Carroll May 2023

Re-Storying Teaching: Using Narradrama To Address Burnout In Public School Teachers, Heather Carroll

Expressive Therapies Capstone Theses

The public school system in the United States is experiencing an increasing crisis in teacher retention and effectiveness due, in part, to the effects of burnout on teaching staff. Teachers often face significant stressors such as tense parent-teacher relationships, state and federal mandates on testing, low financial compensation and limited benefits, and negative sociocultural stereotypes about their roles and responsibilities as educators (Westervelt, 2016; von der Embse et al., 2019). These stressors, if not managed effectively on an individual and systemic level, can lead to burnout (Maslach, 2001). This condition involves symptoms such as emotional and physical exhaustion, disinvestment from …


Text-Based Drama Therapy And Role: Development Of A Method For Identity Integration Of Adolescents Exposed To Trauma At A Partial Hospitalization Program, Daniel Coonan-Helmer May 2023

Text-Based Drama Therapy And Role: Development Of A Method For Identity Integration Of Adolescents Exposed To Trauma At A Partial Hospitalization Program, Daniel Coonan-Helmer

Expressive Therapies Capstone Theses

Trauma interacts with adolescent’s growing understanding of their identity, yet their formative intra- and interpersonal skills may need extra guidance while enrolled in partial hospitalization programs (PHPs). This capstone thesis utilized role method and a selected scene to help adolescents exposed to trauma with identity integration while at a PHP. Through researching adolescent development, trauma, identity, and interactions between those three factors, an intervention was devised to facilitate identity integration using a selected scene from a play independently created of the therapeutic group. The results indicated that there was reflection and perspective growth after the intervention was utilized. The scene …


Perceptions And Impacts Of Unpaid Internships Within Expressive Therapies Education: A Literature Review, Sophie Mcconkie May 2023

Perceptions And Impacts Of Unpaid Internships Within Expressive Therapies Education: A Literature Review, Sophie Mcconkie

Expressive Therapies Capstone Theses

Internships are an essential part of expressive therapies education as they prepare students with the necessary skills for clinical work. In the current model, it has been normalized for internships to be unpaid despite a lack of documented rationale behind this practice. This review uses the available literature on internships to question and critically analyze unpaid internships in expressive therapies education. In recent years, increased criticism has been expressed about the practice of unpaid internships across many industries. Research has shown that students with more connection to social, cultural, and financial capital are favored for internships, creating inequitable access. Those …


66th University Of San Diego School Of Law Commencement Program, 2023, University Of San Diego School Of Law May 2023

66th University Of San Diego School Of Law Commencement Program, 2023, University Of San Diego School Of Law

Commencement Programs

No abstract provided.


Class Of 2023 Commencement, Steve C. Jones May 2023

Class Of 2023 Commencement, Steve C. Jones

Graduation Addresses

Commencement took place on May 20, 2023 to recognize Juris Doctor, Master of Laws and Master in the Study of Law graduates in the University of Georgia School of Law ceremony. The School of Law will held its commencement for the Class of 2023 in the Classic Center Grand Hall. The Honorable Steve C. Jones, U.S. District Judge for the Northern District of Georgia, former Georgia Superior Court judge, 1987 alumni, delivered the keynote address.

A longer set of biographical information related to the speaker was shared alongside other Commencement 2023 details via email, and is duplicated below:

"The Honorable …


Physiological And Behavioral Stress-Induced Responses Of Dogs During Veterinary Examinations, Jessica Ellen Vester May 2023

Physiological And Behavioral Stress-Induced Responses Of Dogs During Veterinary Examinations, Jessica Ellen Vester

Honors Projects

This study investigated whether stress responsiveness in dogs is more significant when the owner is present or absent during a veterinary examination. The study consisted of two experimental groups: "owner absent" and "owner present." Both groups consisted of 25 dogs each, totaling 50 dogs observed. A veterinarian and veterinary assistant recorded the dog's behavioral and physiological stress responses. Each group's behavioral and physiological stress-induced responses were compared using a Fischer Exact test and an Analysis of Covariance. The findings showed that dogs whose owners are present during the veterinary examination display fewer stress responses than dogs whose owners are absent …


Epidemiology Of Island And Mainland Populations: How Does Culture Influence Health Risk Factors Of Non-Communicable, Chronic, And Metabolic Diseases?, Jake Thomas D. Palisoc May 2023

Epidemiology Of Island And Mainland Populations: How Does Culture Influence Health Risk Factors Of Non-Communicable, Chronic, And Metabolic Diseases?, Jake Thomas D. Palisoc

Honors Projects

Non-communicable diseases (NCDs), including chronic and metabolic diseases, are responsible for 74% of global mortality and are strongly influenced by health risk factors. Geographical differences in NCDs have been identified in several countries but have not been completely explained through cultural factors, specifically island and mainland cultures. This study aimed to develop an epidemiological framework for determining diseases with the highest mortality for further investigation regarding different health risk factors rooted in a specific population’s cultural foundations. Preliminary findings indicated diabetes type II (D2) and CKD caused by hypertension and D2 to have the highest risk factor and mortality percentage …


The Role Of Complement In Stroke And Traumatic Brain Injury, Christine Couch May 2023

The Role Of Complement In Stroke And Traumatic Brain Injury, Christine Couch

MUSC Theses and Dissertations

Brain and neural injury are a non-specific disease category that includes traumatic brain injury (TBI) and stroke. Both TBI and stroke are common, costly, and leading causes of severe disability in adults. Both stroke and TBI are responsible for substantial disability in working age adults, with stroke being the second leading cause of death worldwide [1] and TBI a major cause of disability in people younger than their 40's [2]. The immune response after brain injury is multifactorial and involves both local and systemic events at the cellular and molecular level. The complement system is a component of both the …


Audio-Technica Strategic Audit, Caleb Druckemiller May 2023

Audio-Technica Strategic Audit, Caleb Druckemiller

Honors Program: Senior Projects (Public)

Audio-Technica is a multinational audio equipment design and manufacturing company specializing in the production of headphones, microphones, and turntables. The company has been a gold standard for professional use since its inception and has recently ventured into consumer markets. Using both internal and external analysis tools, this audit aims to evaluate how Audio-Technica has established itself in the highly competitive audio equipment industry. Specific techniques include Porter’s Five Forces and PESTEL analyses. After conducting this examination of Audio-Techinca and its industry environment, strategic recommendations will be made to best position the company moving forward.


William & Mary Law School Commencement Exercises (May 20, 2023), William & Mary Law School May 2023

William & Mary Law School Commencement Exercises (May 20, 2023), William & Mary Law School

Commencement Exercises

No abstract provided.


The Influence Of Prison Skills Programming On The Reentry Process, Jennifer Tatten May 2023

The Influence Of Prison Skills Programming On The Reentry Process, Jennifer Tatten

Educational Studies Dissertations

Prison skills programming that is focused on employment readiness, reentry skills, parenting and family relationships, life skills, and anger management is offered with an understanding that the information will support individuals with reentry in areas such as family reintegration and employment. The purpose of this mixed-methods dissertation study was to explore the reasons that individuals chose to participate in skills programming during incarceration and their perceptions about the ways in which skills programming influenced their experiences with family and employment during reentry. Data were collected from diverse participants using a Reentry Experiences Survey (RES) (Appendix A), in-depth interviews, and archival …


Active Imagination, Wellbeing And Ways Of Seeing: A Phenomenological Inquiry Into Experiences Of Adult Learners With Visual Impairments, Steinberg Henry May 2023

Active Imagination, Wellbeing And Ways Of Seeing: A Phenomenological Inquiry Into Experiences Of Adult Learners With Visual Impairments, Steinberg Henry

Educational Studies Dissertations

Six female and two male adult learners who became blind between the ages of 20 and 75 years participated in this study conducted by a blind researcher. The purposely sampled eight were interviewed virtually by way of Zoom. In combination with Johnny Saldana’s work on codes, this study used the NVivo framework for determining structuring categories, selecting node themes, code frameworks and final codes from the first interview. 291 codes were clustered under 26 node themes. NVivo’s word frequency search and Word Tree were applied to clarify and lend a number value to participants’ codes. The second interview, administered after …


Using Vignettes To Change Music Therapists' Attitudes Toward Research, Adrienne Flight May 2023

Using Vignettes To Change Music Therapists' Attitudes Toward Research, Adrienne Flight

Expressive Therapies Dissertations

This study used a three-condition experimental design to determine which was more effective in changing music therapists’ attitudes toward research: a vignette demonstrating positive outcomes of using research to inform clinical work (PO), a vignette showing negative outcomes of not using it to inform clinical work (NO), or a research summary (RS). The outcome measure had three subscales, focused on perceptions of usefulness, anxiety, and positive predispositions.

Respondents (N = 656) included students and professionals. Findings indicated that anxiety decreased more for the RS than the NO condition, F(2, 653) = 4.0, p = .02, η2 = …


From Dread To Aliveness — Bottom-Up Creative Arts Therapies For Resilience In The Face Of Existential Stress: A Literature Review, Anna Olinova May 2023

From Dread To Aliveness — Bottom-Up Creative Arts Therapies For Resilience In The Face Of Existential Stress: A Literature Review, Anna Olinova

Expressive Therapies Capstone Theses

Existential stress results from persistent, uncontrollable personal circumstances or broader systemic factors. Such prolonged stressors constitute “little-t trauma” and take a toll on the body, mind, and spirit. As such, approaches for building resilience against such stressors should be integrative. Because stress implicates the nervous system, bottom-up therapies are foundational in support of building a felt sense of safety. Thereafter, top-down methods for increasing one’s subjective sense of meaning and aliveness can follow. However, traditional psychotherapy approaches to resilience—including those utilized in positive psychology—are often cognitive in nature and disregard the body and nervous system. Literature on bottom-up therapies commonly …