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Baseline Lymphopenia Predicts Survival In Ici-Naïve Solid Tumor Patients Receiving Immune Checkpoint Inhibitors: A Propensity-Matched Real-World Pan-Cancer Analysis., Ahmed Ismail, Nina Balanchivadze, George R Simon, Yanis Boumber

Oncology Articles

Background: Baseline lymphopenia is common among advanced solid tumors and may influence the efficacy/safety of immune checkpoint inhibitors (ICIs), but large real-world evidence is limited. We evaluated the association between baseline absolute lymphocyte count (ALC) and clinical outcomes in adults with solid tumors treated with ICIs in routine practice. Methods: We performed a retrospective cohort study using TriNetX. Adults with solid tumors who received pembrolizumab, nivolumab, or atezolizumab (ICI-Naïve) between January 2015 and June 2026 were included. Baseline ALC was measured within 30 days before first treatment and was classified as lymphopenic (ALC < 1.5 × 109/L) or non-lymphopenic (ALC ≥ 1.5 × 109/L). Propensity score matching (1:1) yielded 5249 patients per group. The index date was the first immunotherapy date, and outcomes were assessed at 6, 12, 24, 36 months, and 5 years. The primary outcome was 24-month overall survival (OS); secondary outcomes were OS at 6 and 12 months and 6-month risks of healthcare utilization, immune-related adverse events (irAEs), and serious infections; and exploratory outcomes included OS at 36 months and 5 years. All outcomes were analyzed using Kaplan-Meier analysis, Cox proportional hazards models, and risk ratios. Subgroup analysis included OS stratified by solid tumor subtypes and prior lines of therapy. Results: After matching, patients with baseline lymphopenia …

Felony Murder: What Courts Ignore In Ohio Rev. Code § 2903.02(B), Richard S. Walinski

Et Cetera

Ohio has two levels of felony murder. One is aggravated felony murder, 2903.01(b). It is an approximate equivalent of the common-law felony-murder rule. The other is a felony-murder rule for the lesser offence of simple murder, 2903.02(B). In felony-murder cases prosecuted under Ohio Revised Code § 2903.02(B), the nearly universal practice among the lower courts in Ohio is to ignore certain explicit text in the statute.

To warrant a conviction, 2903.02(B) requires that death have occurred as a proximate result of the defendant’s having committed or having attempted to commit one of many predicate offenses that the General Assembly labeled …

A Lawyer’S Responsibility To The Rule Of Law, Joseph Mead

Et Cetera

The American legal system faces a growing crisis as the gap between vested rights and judicial remedies expands. Attacks on the legal profession deter lawyers from taking on lawsuits challenging the federal government, potentially expanding the gap between right and remedy. This essay describes how the legal profession has responded to this moment and urges attorneys to renew their commitment to the rule of law.

Composing Playgrounds, Rebecca Suju Abraham

Dartmouth College Master’s Theses

This thesis explores music composition as the design of “playgrounds”: structured systems that invite participation, interaction, and the emergence of shared musical experience. Drawing on a background in engineering and a practice rooted in improvisation and community, I investigate how compositional authority can be exercised through the creation of constraints instead of fixed outcomes. These systems are structured enough to support coordination and open enough to allow for play and collective agency. The work is situated within practice-based research and engages qualitative methods to reflect on a series of projects developed over the course of my MFA in Sonic Practice. …

The Merger Of Short Rising And Falling Pitch Accents In Serbo-Croatian: A Socio-Phonetic Study, Aleksa Sotirov

Linguistics Undergraduate Senior Theses

This thesis is a sociophonetic study investigating the surface realisation of the short-falling and short-rising pitch accents in different dialects of Serbo-Croatian, a South Slavic language. In particular, it investigates the hypothesis of a merger-in-progress between these two pitch accent contours in Belgrade and surrounding areas by analysing phonetic data collected from 17 young speakers of various dialect areas.

The study shows several significant results. We find that the two short accents are, indeed, continuing on their merging trajectory, and most strongly in the Belgrade area. Unexpectedly, we find that they tend to merge in favour of the rising accent, …

Recurrence And Reflection: Psychological Insights From Repetitive Dreams, Annika Cale

University Honors Theses

The most widely reported but least appreciated aspects of human experience are recurring dreams, or those dreams that happen repeatedly with similar themes, imagery, or emotional tone in each episode of the dream. This literature review was based on five relevant psychological sources to explore what common dreams tell about what is going on in the inner psyche of the person having the dream. The synthesis of the empirical literature on recurring dream frequency has been associated with weakened psychological well-being. Longitudinal studies were conducted to show the relationship between recurring dreaming and associated decrease in well-being. These theories are …

The Unspoken And The Unseen: An Analysis Of Victim Gender And Linguistic Framing Of Sexual Assault In Judicial Discourse, Sarnika Ali

Quantitative Social Science Undergraduate Senior Theses

Sexual assault is a profound legal and social crisis. However, it is also fundamentally a linguistic one. The words used, or conspicuously not used, to describe victims, perpetrators, and their actions are not neutral arbiters of fact. They are powerful mechanisms that shape perceptions of harm, attributions of blame, and assignments of credibility. The central battleground for survivors is credibility, and while a “credibility discount” is often applied to female victims, the male victim is rendered nearly invisible. This research is therefore guided by one central, overarching question: how does a sexual assault victim’s gender influence the judicial language used, …

Strategic Anti-Transgender Policy Diffusion: Interest Groups, Courts, And The Two-Track Politics Of Gender Regulation, Henry Danford

University Honors Theses

This thesis analyzes the strategic diffusion of anti-transgender policy in the United States following the passage of Idaho House Bills 500 and 509 in 2020. It argues that conservative lawmakers and advocacy organizations employed a coordinated "two-track" policy strategy in which transgender sports bans served as highly visible and politically popular mode legislation while identity-document restrictions advanced more quietly through courts and administrative policy. Drawing on policy diffusion theory, the Advocacy Coalition framework, and minority stress theory, the study combines qualitative policy analysis with quantitative analysis of Household Pulse Survey mental health data and Media Cloud new coverage data from …

Comprehensive Examination Of Patients’ Data Privacy In Vietnam, Phuong Cham Nguyen

Washington International Law Journal

No abstract provided.

Arab National Security In The Anthropocene Era: Strategic Horizons And The Quest For A Single Security Space (2025–2035), Hamdy A. Hassan

All Works

This study examines evolving dynamics of Arab national security and forecasts developments over the next decade. It identifies key determinants, including political stability, economic resilience, military capability, and social cohesion, while accounting for geopolitical shifts, technological change, climate pressures, and global power realignments. Employing a qualitative survey design, the research draws on semi-structured interviews with 112 regional security and policy experts and applies thematic analysis. Findings indicate that limited regional cooperation and weak economic performance undermine Arab national security. Looking toward 2035, the study anticipates foreign intervention, internal instability, and significant changes in alliances and technological utilization. The research underscores …

Gamification By Design: Methodological Foundations Of The Gamespro Speaking Model For Primary Education, Mohd Zulhairi Che Abd Rahman, Hasiah Mohamed, Siti Zulaiha Ahmad, Aurelio P. Vilbar

Journal of Informatics and Web Engineering

This study presents the development and validation of the GAMESPro model, a structured gamification model designed to enhance English-speaking proficiency among Malaysian primary school students. Despite national reforms and policy initiatives aimed at improving communicative competence, oral English skills remain underdeveloped, particularly in rural and resource-constrained schools. Existing gamification practices in Malaysian classrooms often rely on isolated digital tools and lack pedagogical coherence. Addressing this gap, the study employed the Design and Development Research (DDR) methodology, encompassing three phases: Needs Analysis, Design and Development, and Evaluation. A Systematic Literature Review identified key gamification principles, while validation of ten experts confirmed …

The Development Of Decentralized Ticketing System Using Web3, Yu-Xian Cheng, Kah-Ong Michael Goh, Check-Yee Law, Connie Tee, Yong-Wee Sek, Md Ismail Hossen

Journal of Informatics and Web Engineering

Traditional ticketing systems often suffer from major drawbacks such as ticket fraud, duplication, inflated resale prices, lack of transparency, and centralized control over transactions. These issues result in reduced trust and limited flexibility for both event organizers and ticket buyers, especially in unregulated secondary markets. To address these gaps, this paper presents the design and development of a Decentralized Ticketing System (DTS) using Web3 technologies. The system leverages Ethereum blockchain, smart contracts written in Solidity, and NFT-based ticket issuance to ensure security, transparency, and verifiable ownership. Features include wallet-based login via MetaMask, multi-ticket purchasing, QR-based validation, controlled resale pricing, and …

An Ai-Based Framework For Heart–Brain–Body Coherence In Wellness Monitoring: A Longitudinal Simulation Study, Asiah Lokman, Akalpita Tendulkar, Yujiao Zhang, Mantena Sireesha

Journal of Informatics and Web Engineering

Present wellness monitoring systems primarily emphasize single-modality metrics, neglecting the intricate, interdependent interactions among cardiac, neural, and behavioral regulatory systems. This paper introduces a machine learning framework that implements heart–brain–body coherence as a dynamic, longitudinally evaluated wellness metric. In contrast to previous simulation-based studies that utilized independently generated, cross-sectional data categorized by deterministic IF-THEN rules, the current study adopts a longitudinal simulation design featuring 80 virtual subjects monitored across 30 consecutive daily profiles (N=2,400 records). This design incorporates physiologically realistic inter-variable correlations and probabilistic coherence labelling derived from a continuous risk-scoring function. The subject-level train/test split (56 training subjects, 1,680 …

Multi-Agent Ai Systems For Detecting Emerging Therapeutic Targets And Intervention Patterns In Neuroplasticity Research, Raza Hasan, Salman Mahmood

Journal of Informatics and Web Engineering

The exponential growth of neuroplasticity research presents profound challenges to the manual synthesis of literature, hindering the identification of emerging therapeutic targets and intervention patterns. While multi-agent Artificial Intelligence (AI) systems have been proposed conceptually to address this, concrete implementations demonstrating end-to-end utility are scarce. This paper details the successful implementation and application of a novel four-agent AI system designed to automate the discovery, extraction, analysis, and validation of patterns in neuroplasticity literature. Our platform consists of four parts: a Literature Discovery Agent (LDA) for corpus gathering, a Concept Extraction Agent (CEA) with a multi-level NLP strategy fallback mechanism for …

Ai-Powered Continuous Health Monitoring For Chronic Disease Management In Malaysia: Real-Time Risk Prediction Using Wearable Sensors And Digital Biomarkers, Umi Najiah Ahmad Razimi, Yong Yoke Leng, Nor Hapiza Mohd Ariffin, Mohammed Hazim Alkawaz

Journal of Informatics and Web Engineering

Chronic Non-Communicable Diseases (NCDs), such as diabetes mellitus, hypertension, and cardiovascular disease, make up a significant portion of the mortality cases in Malaysia, as well as impose consistent demands for costs related to health care expenditure. According to the cost reports at the national level, major NCDs (cardiovascular disease, diabetes, and cancer) are responsible for RM 9.65 billion annually as direct healthcare cost [3]. However, the current approach to managing chronic diseases focuses heavily on periodic assessments in clinic setting at weekly or monthly intervals. Here, a predictive analysis framework based on AI technology, leveraging continuous monitoring with patient data …

Global Health Governance Or Global Governance For Health? Navigating The Path For Pandemic Preparedness, Kadria Abdelmotaal

Theses and Dissertations

Abstract

The COVID-19 pandemic constituted a systemic stress test for global health governance, exposing structural and institutional weaknesses in national and international response systems. Although health system financing and income levels influenced baseline capacity, this dissertation demonstrates that governance performance was a decisive determinant of pandemic outcomes, shaping intervention timing, vaccine equity, and preventable mortality.

Drawing on governance theory, empirical analysis, and policy-oriented legal evaluation, this research examines whether pandemic preparedness can be achieved through strengthening Global Health Governance (GHG) alone, or whether a broader paradigm of Global Governance for Health (GGFH) is required. GGFH reconceptualizes preparedness as embedded within …

A Poet Bears Witness: An Interview With M. L. Williams On The Function Of Literary Studies In Troubled Times, Leah Toth, M. L. Williams

Critical Humanities

Dr. M. L. (Marty) Williams is a poet and professor of literature at Valdosta State University, a comprehensive university in south-central Georgia. He is the author of Game (What Books Press 2021), Other Medicines (Redbone Chapbooks 2008) and co-editor of How Much Earth: The Fresno Poets (Roundhouse Press 2001). The focus of the interview that follows is the future of literary studies in the modern neo-liberal university, a daunting topic in 2026, in the face of what many administrators refer to as the "right-sizing" of literature programs nationwide in both the U.S. and the U.K. Anybody paying attention to the …

Navigating Prose, Poetry And Criticism: An Interview With Nasir Abbas Nayyar On His Contribution To Urdu Literature And Literary Criticism, Nasir Abbas Nayyar, Inayat Ullah

Critical Humanities

Navigating Prose, Poetry and Criticism: An Interview with Nasir Abbas Nayyar on His Contribution to Urdu Literature and Literary Criticism 

Submitted: May 24, 2026

Accepted: June 1, 2026

“Politics Are Downstream From Culture”: An Interview With Paul Lauter, Paul Lauter

Critical Humanities

“Politics are downstream from culture”: An Interview with Paul Lauter

Submitted: May 29, 2026

Accepted: June 1, 2026

Implementing 21st Century Skills In Quranic Education: A Case Study Of Sub-Saharan African Students Within Quranic Schools In The Souss Region Of Morocco, Ahmed Abaragh, Lahoussine Hamdoune

Critical Humanities

To help Sub-Saharan African students meet their needs in a globalized era, this article seeks to shed light on the essence of integrating or implementing 21st century skills into Quranic education within the Quranic schools in the Souss region of Morocco. The choice of southern Moroccan Quranic Schools, as the research area is due to its historically vibrant culture and the high-quality training provided by well-versed teachers and jurists. Based on the social ecology of human development theory with the use of a qualitative approach, the analysis highlights the prominent role of implementing critical thinking and problem-solving, communication and collaboration, …

The Possibility Of Post Binary Reflexivity: A Genealogy Of Binary Logic In Western Philosophy, Vaughan A. Bidois

Critical Humanities

This article traces a genealogy of binary logic within Western philosophy, from its origins in Platonic metaphysics through to its deconstruction in poststructuralist theory. Drawing on the genealogical methods of Friedrich Nietzsche and Michel Foucault, it critiques how oppositional structures, such as mind/body, reason/emotion, and truth/error, have persisted through shifting intellectual paradigms while shaping knowledge, power, and subjectivity. Structuralist and linguistic theories are examined for their role in reinforcing binary meaning-making, while poststructural critiques (notably Derrida and Foucault) are explored for their attempts to subvert such hierarchies. However, the article argues that these critiques remain paradoxically ensnared within the same …

Human Wisdom And Artificial Intelligence: Role Of Liberal Arts Education In A Neoliberal World, Purna Chandra Bhusal

Critical Humanities

Neoliberalism is an economic and political ideology that originated in the 1930s and 40s, gained momentum in the late 70s and 80s, and peaked in the 90s and 2000s. Since its inception, neoliberalism has promoted a free-market economy with minimal state intervention, granting individuals the freedom to compete and succeed. Since the last quarter of the twentieth century, the neoliberal system has invested in, incorporated, and promoted Artificial Intelligence (AI), valuing an AI-enhanced corporate ethos. As a result, the success of higher education is generally measured by the quantity of technologically sound, market-ready, AI-trained human capital it produces for industry. …

Why Literature Matters: Perpetrator Portrayal, Cultural Imaginaire And Poetry Of The Taliban, Inayat Ullah

Critical Humanities

The question of how perpetrators of violence are identified, represented and understood has become a central concern of Perpetrator Studies, an interdisciplinary field that emerged in the early twenty-first century. This article analyzes The Poetry of the Taliban in a bid to examine how the selected poems construct and negotiate multiple figurations of the perpetrator rather than presenting it as a singular or fixed category. While the poems frequently identify perpetrator through recognizable political, military and ideological structures, they also reveal the complexities involved in reducing the perpetrator to a clearly identifiable form or kind. In exploring these tensions, the …

Literature Carries Philosophy’S Open Secret: On Derrida’S Reading Of Romeo And Juliet, Rajesh Sampath

Critical Humanities

This paper attempts a close reading of Derrida’s texts, particularly with a focus on his brief but significant reading of Shakespeare’s The Tragedy of Romeo and Juliet in “Aphorism Countertime” (originally published in French in 1986). We compare this short work with his more sustained engagement with the philosophy of death in Aporias (1993), which itself is an attempted critique of Heidegger’s Being and Time (1927); the latter is, arguably, the most influential work of twentieth-century continental European philosophy, particularly on issues of time, death, and authentic life. The paper tries to show that a fruitful engagement between philosophy and …

Evaluating The Impact Of Early Contractor Involvement On Enhancing The Performance Of Construction Projects In Egypt, Samah Saleh Abdelraof, Ayman Ahmed Ezzat Othman, Lamees Mostafa Ahmed

Mansoura Engineering Journal

The construction industry constitutes a critical pillar of Egypt’s national economic growth and sustainable development. Despite its strategic importance, the sector continues to face persistent challenges, including chronic cost overruns, schedule delays, and inadequate coordination among stakeholders. These inefficiencies are largely attributed to the dominance of the traditional Design–Bid–Build (DBB) system, which enforces a rigid separation between design and construction, fostering adversarial relationships and project disputes, which highlights the need for alternative procurement approaches. This research investigates the impact of Early Contractor Involvement (ECI) as a collaborative procurement alternative to enhance project performance. Case studies show that ECI improves early-stage …

The Role Of The Cdg Group In Property Development, Moha Ben Satti

Revue Marocaine de Droit, d'Economie et de Gestion (Moroccan Journal of Law, Economics and Management)

Since its creation in 1959, the CDG (Caisse de Dépôt et de Gestion) has continuously strengthened its intervention in the highly social real estate sector to contribute toward placing a significant number of decent housing units at reasonable prices on the market. This choice is justified by the nature of the Caisse's resources, primarily constituted from CNSS affiliate contributions and popular savings collected by CEN. After focusing its first fifteen years on establishing appropriate intervention instruments through generalized housing promotion, the CDG adopted a new orientation from 1975 onward, particularly from the 1980s, marked by massive housing programs for low-income …

An Exploration Of The Experiences Of Black Women College Leaders: Reflections On Support, Amplifiers, Barriers, And Success As Leaders In Higher Education, Katherine L. Acevedo

Student Theses

Black women have had to deal with the “double jeopardy” of race and gender in higher education for centuries (Khosroshahi, 2021). This qualitative study explored the lived experiences of Black women serving in senior-level leadership roles within institutions of higher education (IHEs) in New York State. Utilizing aspects of phenomenological methodology informed by Black Feminist Thought (BFT) (Collins, 1989, 2000, 2022), this study amplifies the voices of Black women senior-level leaders, centering their narratives to understand how race and gender shape their professional journeys, challenges, and strategies for success. Ten participants, all self-identified Black women with at least 3 years …

Mothers’ Childhood Maltreatment And Developmentally Appropriate Attributions Of 12-Month-Old Infants, Katelyn M. Lamberton

Undergraduate Theses, Capstones, and Recitals

This study examined associations between developmentally appropriate attributions (DAAs), an understudied construct, with maternal history of childhood maltreatment and maternal reflective functioning (RF) with their 12-month-old infants. The study examined if 1) DAAs at 12 months were concurrently associated with parental RF at 12 months for construct validity, and 2) higher levels of maternal childhood maltreatment were associated with lower DAAs for predictive validity. Participants were 156 mothers (40.0% White, 25.5% Latinx, 14.9% Black, 5.5% Asian, 2.1% Native-American, 12.0% biracial/multiracial) and their 12- to 15-month infants. Childhood maltreatment and RF were assessed by parental self-report at three-months and 12-months postpartum …

The Contentious Politics Of Abortion: Understanding The Black Protests And Women’S Strikes In Poland, Taubie Sanders

Undergraduate Theses, Capstones, and Recitals

In 1993, the Polish Parliament, the Sejm, passed a law called ‘The Abortion Compromise’ permitting abortion only in cases when there is a serious threat to the life or health of the woman, pregnancy is the result of a crime, or prenatal tests show the fetus to be severely or incurably damaged. The current abortion laws in Poland are the most restrictive in all of Europe. Poland’s abortion laws have undergone much contestation in recent years. In 2016, the Black Protests erupted across the country in opposition to a proposed total ban on abortion. In 2020, the Women’s Strikes commenced …

Digital Bodily Autonomy: Consent Issues, Labor Displacement, And Legal Understandings Of Ai Generated Deepfake Pornography, Mariah Barrett

Undergraduate Theses, Capstones, and Recitals

In the United States, nonconsensual pornographic deepfakes are becoming an increasingly prevalent problem as AI deepfake creation software improves and becomes widely available. Despite this, patchwork legislation across the country is inconsistent and conflicting regarding this issue. In this paper, I explore the background of pornography and obscenity laws and demonstrate how these frameworks are not properly constructed to apply to the digital sphere. Then, I address major themes within deepfake literature such as consent issues, bodily autonomy, labor displacement, and verifiable identity as a commodity through the case study of OnlyFans. I explore current and proposed legislation within the …