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The Prenatal Diagnosis And Perinatal Management Of Congenital Long Qt Syndrome: A Comprehensive Literature Review And Recent Updates., Stefani Samples, Sara Cherny, Nitin Madan, Jeff Hong, Sheena A. Mansukhani, Janette F. Strasburger, Michael R. Carr, Sheetal R. Patel Apr 2025

The Prenatal Diagnosis And Perinatal Management Of Congenital Long Qt Syndrome: A Comprehensive Literature Review And Recent Updates., Stefani Samples, Sara Cherny, Nitin Madan, Jeff Hong, Sheena A. Mansukhani, Janette F. Strasburger, Michael R. Carr, Sheetal R. Patel

Manuscripts, Articles, Book Chapters and Other Papers

Congenital long QT syndrome (LQTS) is a group of heritable conditions that are associated with cardiac repolarization abnormalities characterized by QT prolongation on electrocardiogram and the risk of life-threatening arrhythmias. The prenatal detection of LQTS presents significant challenges for clinicians, and a multidisciplinary approach is required for optimal prenatal and postnatal management. In this comprehensive literature review, we describe strategies for the fetal diagnosis of LQTS with variable initial presentation, genetic testing in suspected fetal LQTS, the utility of fetal magnetocardiography as an additional diagnostic tool, prenatal management, and postnatal treatment. We focus on a multidisciplinary team approach including fetal …


Capital Stack Ut Llc, Appellee V. Gowtham Reddy; Genesis Capital Investments, Llc; Jga Development, Llc; Genesis Opportunity Zone Fund; Shiva Holdings, Llc; And Project 557 First St Development, Appellants : Reply Brief, Utah Court Of Appeals Apr 2025

Capital Stack Ut Llc, Appellee V. Gowtham Reddy; Genesis Capital Investments, Llc; Jga Development, Llc; Genesis Opportunity Zone Fund; Shiva Holdings, Llc; And Project 557 First St Development, Appellants : Reply Brief, Utah Court Of Appeals

Utah Court of Appeals Briefs (2020 –)

On appeal from the Third Judicial District Court, Salt Lake County Honorable Patrick Corum

Kennedy D. Nate, Austin C. Nate, Counsel for Appellants

Erik A. Christiansen, Alan S. Mouritsen, Alex N. Vandiver, Counsel for Appellee


28-18 31st St., Llc V. Muso Apr 2025

28-18 31st St., Llc V. Muso

All Decisions

In this non-payment case, the tenant moved under CPLR 5015(a)(1) to vacate a February 2023 default judgment, claiming medical issues, including seizures and memory loss, as her excuse. However, the court found no medical documentation linking her condition to the default, rendering the excuse unsubstantiated and legally insufficient. The court declined to consider the alleged defense of no valid lease due to the failure to show a reasonable excuse. Although denying the motion to vacate, the court granted a short stay of eviction conditioned upon substantial rent arrears payment. Practice Note: Courts strictly enforce documentation requirements for medical excuses; unsupported …


Garcia V. Nelson, Et Al Apr 2025

Garcia V. Nelson, Et Al

All Decisions

Handwritten opinion. In this no-ground holdover proceeding, the landlord sought possession from a Section 8 voucher tenant without pleading the premises' regulatory status or complying with the Williams Consent Decree, which mandates service on NYCHA. The tenant promptly moved to dismiss under CPLR § 3211(a)(7), asserting that the omissions were fatal under RPAPL § 741(4) and federal regulations. The landlord, who had signed a Section 8 contract, did not dispute the unit's subsidized status but argued that NYCHA's subsidy cessation excused compliance. The court rejected this, emphasizing strict pleading and service requirements in federally subsidized tenancies. Additionally, the court found …


Chimes: April 14, 2025, Calvin University Apr 2025

Chimes: April 14, 2025, Calvin University

Chimes

Students lead pro-DEI protest on campus by Addy Offutt & Ethan Meyers

Men's tennis rallies with three straight sweeps; eyes MIAA title, shot at nationals by Zach Kern

Professors discuss effects of second Trump term by Grace Buller

"One God, Man Perspective" by Gregory Mox & Eric Rackard

" A Minecraft Movie" does its best to wreck my favorite thing by Marcail Schuurmann

Calvin's "Meet the Turtles" Event Aims to Connect Students with Nature and Community by Reuben Kok


Implications For The Dollar Of Central Bank Digital Currencies, Ross P. Buckley Apr 2025

Implications For The Dollar Of Central Bank Digital Currencies, Ross P. Buckley

Law and Contemporary Problems

No abstract provided.


The Eu Approach To Digital Currencies, Dirk Zetzsche, Julia Sinnig Apr 2025

The Eu Approach To Digital Currencies, Dirk Zetzsche, Julia Sinnig

Law and Contemporary Problems

No abstract provided.


Proprietary Rights And Digital Assets: A "Modest Proposal" From A Transnational Law Perspective, Louise Gullifer, Ignacio Tirado Apr 2025

Proprietary Rights And Digital Assets: A "Modest Proposal" From A Transnational Law Perspective, Louise Gullifer, Ignacio Tirado

Law and Contemporary Problems

No abstract provided.


An Exploration Of The Relationship Between Divorce And Children Of Divorce’S Romantic Relationships In Adulthood, Carlie Mccleary Apr 2025

An Exploration Of The Relationship Between Divorce And Children Of Divorce’S Romantic Relationships In Adulthood, Carlie Mccleary

Student Works

Divorce is a common occurrence in around 50% of marital relationships, and has profound effects on children born within those unions, particularly in their adult, romantic relationships. In this literature review, I compiled 12 sources from three journals in order to explore the relationship between divorce and children’s romantic relationships in the future. Primarily, findings indicated two major outcomes for children of divorce: lack of respect for the institution of marriage and also a lower level of commitment to their romantic partners. Both of these in turn impact their current and future relationships by lowering their overall satisfaction and investment …


Culture Trap: Male Educators Of Color And The Academic Role Deficit, Javin Cotton Apr 2025

Culture Trap: Male Educators Of Color And The Academic Role Deficit, Javin Cotton

School of Education Capstone Projects

The purpose of this capstone project is to investigate the systemic barriers that limit the academic career advancement of male educators of color within the educational system, specifically highlighting School District 88. This study specifically addresses the disproportionate placement of Black and Latino male educators into disciplinary roles rather than academic leadership positions. Utilizing Implementation Science principles, the project outlines a multi-faceted intervention plan designed to dismantle implicit biases, enhance mentorship opportunities, and establish structured pathways for professional growth. By promoting equity- driven hiring practices, mentorship programs, and policy reforms, this capstone seeks to increase the representation of male educators …


Systemic Failures Of The Criminal Justice System, Isabella Lucero Apr 2025

Systemic Failures Of The Criminal Justice System, Isabella Lucero

Honors Program: Senior Projects (Public)

America’s history as a nation that was founded on the unjust treatment of the people of color has forever shaped the way our justice system has evolved. From slavery to “Black Codes” to Jim Crow Laws, the system has never been set up for equal administration of justice. The purpose of this essay is to evaluate how the Criminal Justice System disadvantages and targets individuals at all stages of justice involvement, with a particular focus on individuals from communities of color.


The Hill We Climb: A Mixed Methods Exploration Of Stress And Depression In A Community Sample, Akilah Collins-Anderson Apr 2025

The Hill We Climb: A Mixed Methods Exploration Of Stress And Depression In A Community Sample, Akilah Collins-Anderson

Brown School Graduate Student Theses and Dissertations

While research on Black mental health has increased over the past decade, there remain strides to make with regard to the investigation of the relationship between stress and depression among Black Americans. For decades, stress process scholars have documented that negative, adverse experiences have consequences for mental health conditions, such as depression. Stress process theory predicts that greater exposure to stressors and limited access to coping resources increase the risk of poor mental health. Therefore, socially disadvantaged groups such as Black Americans would be expected to be at great risk of mental health conditions due to previous exposure to stressors. …


Displaced Decarbonization: Climate Necropolitics And The Contested Spatialities Of Green Hydrogen In Namibia, Meredith J. Deboom Apr 2025

Displaced Decarbonization: Climate Necropolitics And The Contested Spatialities Of Green Hydrogen In Namibia, Meredith J. Deboom

Faculty Publications

Green hydrogen is often presented as a transformative solution to the dual challenges of decarbonization and economic development. This article applies the framework of climate necropolitics to interrogate the contested spatialities underlying such “win-win” narratives. It does so through an extended case study of Hyphen Hydrogen Energy, a $10 billion green hydrogen project planned for Lüderitz, Namibia. A remote town of 20,000 in a country with a $12 billion annual GDP, Lüderitz initially appears to be an unlikely host site for the “industrial fuel of the future.” To explain this outcome, I first illustrate how discordant socio-spatial projects—including European energy …


Detection Of Endocrine Disrupting Chemicals At The North Haven Water Pollution Control Facility On The Quinnipiac River, Kacey Daly Apr 2025

Detection Of Endocrine Disrupting Chemicals At The North Haven Water Pollution Control Facility On The Quinnipiac River, Kacey Daly

Honors Theses

The presence of estrogenic endocrine disrupting chemicals (EDCs) was detected using vacuum filtration and solid-phase extraction (SPE) followed by methods measured through chemical analysis. This research aims to quantify the presence of estrogenic EDCs in the Quinnipiac River located in Connecticut. Samples from influent, effluent, and downstream river locations from a Water Pollution Control Facility (WPCF) in North Haven, Connecticut are tested for the presence of estrone and 17α-ethinylestradiol. Findings from the study will provide insight to improve treatment efficiency of EDCs in WPCFs.


Complexity, Coordination, And The Politics Of Global Health Emergencies: Institutions, Actors, And Responses, Jennifer M. Kerner Apr 2025

Complexity, Coordination, And The Politics Of Global Health Emergencies: Institutions, Actors, And Responses, Jennifer M. Kerner

Political Science ETDs

This dissertation examines the politics of global health emergencies through three interconnected studies. First, it analyzes the declaration of Public Health Emergencies of International Concern (PHEICs), revealing that while World Health Organization (WHO) protocols influence decisions, political factors may also play a role. Second, a case study of the 2014 Ebola outbreak explores the complexities of international response coordination. It highlights the importance of established protocols, clear leadership, and effective communication, while also noting the challenges posed by resource constraints and inter-organizational dynamics. Third, the research investigates the impact of military involvement in global health emergencies. It reveals that military …


Tales About Afghan Women After The U.S. Lost The War In Afghanistan In 2021: A Frame Analysis Of Coverage In The New York Times, Ismat Ara Begum Apr 2025

Tales About Afghan Women After The U.S. Lost The War In Afghanistan In 2021: A Frame Analysis Of Coverage In The New York Times, Ismat Ara Begum

Communication ETDs

This study investigates how U.S. news media framed Afghan women’s identities and experiences in the context of the Taliban’s return to power after the U.S. military withdrawal of troops from Afghanistan. In this qualitative inquiry, I examined 11 in-depth, human-interest stories in The New York Times, a mainstream news organization known for its influence on coverage of international and global affairs. A frame analysis was applied to identify salient frames and their ideological underpinnings. The findings show two dominant frames in the coverage, women’s rights and victimhood, articulated through three rhetorical strategies—binary oppositions, comparing loss vs. gain, and emphasis on …


Integrating Short-Read And Long-Read Single-Cell Rna Sequencing For Comprehensive Transcriptome Profiling In Mouse Retina, Soo Hwan Oh, Yexuan Cao, Rui Chen Apr 2025

Integrating Short-Read And Long-Read Single-Cell Rna Sequencing For Comprehensive Transcriptome Profiling In Mouse Retina, Soo Hwan Oh, Yexuan Cao, Rui Chen

Faculty, Staff and Students Publications

The vast majority of protein-coding genes in the human genome produce multiple mRNA isoforms through alternative splicing, significantly enhancing the complexity of the transcriptome and proteome. To establish an efficient method for characterizing transcript isoforms within tissue samples, we conducted a systematic comparison between single-cell long-read and conventional short-read RNA sequencing techniques. The transcriptome of approximately 30,000 mouse retina cells was profiled using 1.54 billion Illumina short reads and 1.40 billion Oxford Nanopore Technologies long reads. Consequently, we identify 44,325 transcript isoforms, with a notable 38% previously uncharacterized and 17% expressed exclusively in distinct cellular subclasses. We observe that long-read …


Closing The Gaps, And Improving Somatic Structural Variant Analysis And Benchmarking Using Chm13-T2t, Erin Pleasance, Vanessa L Porter, Steven J M Jones, Fritz J Sedlazeck Apr 2025

Closing The Gaps, And Improving Somatic Structural Variant Analysis And Benchmarking Using Chm13-T2t, Erin Pleasance, Vanessa L Porter, Steven J M Jones, Fritz J Sedlazeck

Faculty, Staff and Students Publications

The complexities of cancer genomes are becoming more easily interpreted due to advancements in sequencing technologies and improved bioinformatic analysis. Structural variants (SVs) represent an important subset of somatic events in tumors. While the detection of SVs has been markedly improved by the development of long-read sequencing, somatic variant identification and annotation remain challenging. We hypothesized that the use of a completed human reference genome (CHM13-T2T) would improve somatic SV calling. Our findings in a tumor-normal matched benchmark sample and three patient samples show that the CHM13-T2T improves SV detection accuracy compared to GRCh38 with a notable reduction in false-positive …


Update On Cancer And Central Nervous System Tumor Surveillance In Pediatric Nf2-, Smarcb1-, And Lztr1-Related Schwannomatosis, Mary-Louise C Greer, Sarah R Scollon, Sarah G Mitchell, Jordan R Hansford, Kris Ann P Schultz, Wendy K Kohlmann, Jennifer M Kalish, Suzanne P Macfarland, Anirban Das, Kara N Maxwell, Stefan M Pfister, Rosanna Weksberg, Orli Michaeli, Uri Tabori, Gina M Ney, Philip J Lupo, Jack J Brzezinski, Douglas R Stewart, Emma R Woodward, Christian P Kratz Apr 2025

Update On Cancer And Central Nervous System Tumor Surveillance In Pediatric Nf2-, Smarcb1-, And Lztr1-Related Schwannomatosis, Mary-Louise C Greer, Sarah R Scollon, Sarah G Mitchell, Jordan R Hansford, Kris Ann P Schultz, Wendy K Kohlmann, Jennifer M Kalish, Suzanne P Macfarland, Anirban Das, Kara N Maxwell, Stefan M Pfister, Rosanna Weksberg, Orli Michaeli, Uri Tabori, Gina M Ney, Philip J Lupo, Jack J Brzezinski, Douglas R Stewart, Emma R Woodward, Christian P Kratz

Faculty, Staff and Students Publications

Schwannomatosis (SWN) is a distinct cancer predisposition syndrome caused by germline pathogenic variants in the genes NF2, SMARCB1, or LZTR1. There is a significant clinical overlap between these syndromes with the hallmark of increased risk for cranial, spinal, and peripheral schwannomas. Neurofibromatosis type 2 was recently renamed as NF2-related SWN and is the most common SWN syndrome, with increased risk for bilateral vestibular schwannomas, intradermal schwannomas, meningiomas, and less commonly, ependymoma. SMARCB1-related SWN is a familial SWN syndrome associated with peripheral and spinal schwannomas and an increased risk for meningiomas and malignant peripheral nerve sheath tumors, even in the absence …


Somatodendritic Orientation Determines Tdcs-Induced Neuromodulation Of Purkinje Cell Activity In Awake Mice, Álvaro Sánchez-López, Javier F Medina, Javier Márquez-Ruiz Apr 2025

Somatodendritic Orientation Determines Tdcs-Induced Neuromodulation Of Purkinje Cell Activity In Awake Mice, Álvaro Sánchez-López, Javier F Medina, Javier Márquez-Ruiz

Faculty, Staff and Students Publications

Transcranial direct-current stimulation (tDCS) of the cerebellum is a promising non-invasive neuromodulatory technique being proposed for the treatment of neurological and neuropsychiatric disorders. However, there is a lack of knowledge about how externally applied currents affect neuronal spiking activity in cerebellar circuits in vivo. We investigated how Cb-tDCS affects the firing rate of Purkinje cells (PC) and non-PC in the mouse cerebellar cortex to understand the underlying mechanisms behind the polarity-dependent modulation of neuronal activity induced by tDCS. Mice (n=9) were prepared for the chronic recording of local field potentials (LFPs) to assess the actual electric field gradient imposed by …


How Do Life And Non-Life Insurance Affect Financial Inclusion? New Empirical Evidence From A Cross-Country Analysis, Shen Yap, Huishan Lee, Ping Xin Liew Apr 2025

How Do Life And Non-Life Insurance Affect Financial Inclusion? New Empirical Evidence From A Cross-Country Analysis, Shen Yap, Huishan Lee, Ping Xin Liew

Bulletin of Monetary Economics and Banking

This paper examines the influence of life and non-life insurance on financial inclusion in 79 countries during 2019. Financial inclusion indices were calculated using the Euclidean distance approach. The study reveals that the financial inclusion level is considerably impacted by the integration of insurance indicators. In over 64% of the countries, the financial inclusiveness is reduced as a result of the incorporation of life insurance. In contrast, the financial inclusiveness of nearly 47% of the countries was enhanced by the inclusion of non-life insurance. The paper emphasizes the necessity for policymakers to take insurance into account as a critical element …


Colonial Legacies And Gender Equality: A Study Of Women’S Rights In Angola & Namibia, Anna E. Stephens Apr 2025

Colonial Legacies And Gender Equality: A Study Of Women’S Rights In Angola & Namibia, Anna E. Stephens

Global Tides

Angola and Namibia, neighboring countries in southwestern Africa, share a history of colonial exploitation and rich natural resources, yet diverge sharply in their post-independence trajectories concerning gender equality. This paper employs the method of difference to investigate how Namibia emerged as a continental and global leader in advancing women’s rights, while Angola continues to face significant challenges. It argues that Namibia’s inclusive liberation movement and peaceful, UN-brokered decolonization contrast with Angola’s prolonged and violent colonial legacy under Portugal, which culminated in a devastating civil war. The paper also considers how Namibia’s smaller population may have fostered greater unity and gender …


The Increasing Prevalence Of Cyber Operations And The Inadequacy Of International Law To Address Them, Gabriel Smedes Apr 2025

The Increasing Prevalence Of Cyber Operations And The Inadequacy Of International Law To Address Them, Gabriel Smedes

Global Tides

This paper is a synthesis research article analyzing the legality of cyber operations within the international legal sphere. It works to define cyber operations and differentiate them from similar identifiers. The study looks to existing contributions to international law and explores how some existing some existing regulation is challenging to apply and it is difficult to implement new legislation. Highlighting the importance of legislation and regulations on cyber operations due to their increasing prevalence and danger.


The Role Of Libraries In The Fight Against Corruption, Ganiyu Idowu Buhari, Rotimi Adesina Egunjobi Dr. Apr 2025

The Role Of Libraries In The Fight Against Corruption, Ganiyu Idowu Buhari, Rotimi Adesina Egunjobi Dr.

Library Philosophy and Practice (e-journal)

Corruption is simply a misuse of entrusted authority for personal benefit of self, family, friends and those who by rules do not deserve or qualify to get the benefit of that authority. The phenomenon which has been described as a universal one, presents itself in different forms like embezzlement, bribery, nepotism in public sector recruitment, promotion and access to public service, cronyism, vote-buying, political patronage, and judicial corruption. The effects of this phenomenon on the society are so monumental that a common platformmust be found to wage war against it, if our country’s plan for economic growth and development must …


What You See Is Not What You Get: Food Advertising Amidst The Global Overweight And Obesity Pandemic, Marija Ocokoljic Apr 2025

What You See Is Not What You Get: Food Advertising Amidst The Global Overweight And Obesity Pandemic, Marija Ocokoljic

Journal of Marketing and Consumer Behaviour in Emerging Markets

The tandem issue of obesity and overweight is a serious global issue that has attained pandemic scale. Media, particularly advertising, plays an active role in shaping perceptions and behavioural patterns, influencing both how and what people eat. This paper analyses food advertising in Serbia in 2023 in the context of promoting dietary habits. Content analysis of commercials aired on a selection of television stations during the year showed the overwhelming prevalence of ads for food high in fat, sugar, and salt (HFSS), with confectionary products in lead positions. Commercial narratives centre on framing them as sources or catalysts for joyful, …


On A Roll? Or Is It A Slide? Alaska's Budgeting Process In 2024, Glenn Wright Apr 2025

On A Roll? Or Is It A Slide? Alaska's Budgeting Process In 2024, Glenn Wright

Faculty, Staff, and Students

As in 2023, Alaska’s politics seem to be benefitting from a more moderate and collegial policymaking environment and possibly even more sensible budgetary policy. In part, this seems due to Alaska’s adoption of a new election system which in 2022 generated a more moderate set of legislative coalitions than the previous several election cycles. These moderate coalitions may be short-lived, however, as an effort to repeal the new election system is underway. And even with our relatively moderate State House and State Senate coalitions, headwinds and controversies remain, especially issues around public education funding.


Climate Exceptionalism In Court, Zachary D. Clopton, David A. Dana Apr 2025

Climate Exceptionalism In Court, Zachary D. Clopton, David A. Dana

Northwestern University Law Review

Across a range of cases, fossil fuel companies, government actors, and some judges have conceded that climate change is an exceptional phenomenon, only to argue that its exceptional nature is a reason to keep climate change out of court. These parties and judges thus seek to avoid the adjudication of climate cases on the merits, even when the neutral application of existing law would provide for jurisdiction in these cases. We term this phenomenon “climate jurisdiction exceptionalism.”

This Article provides a comprehensive account of climate jurisdiction exceptionalism, focusing on two main threads: Article III standing and state court jurisdiction. First, …


Preclusive Jurisdictional Dismissals, Kevin Song Apr 2025

Preclusive Jurisdictional Dismissals, Kevin Song

Northwestern University Law Review

Every litigant deserves their day in court. At the same time, litigants cannot endlessly go to court on the same matter. A complex body of preclusion law balances these fundamental tenets by examining when adjudication of a matter precludes subsequent relitigation. This body of law has evolved over time to preserve the day-in-court ideal in a way that is sensitive to the threats that relitigation present to judicial efficiency, fair adjudication, and repose. Modern preclusion law has settled on a pragmatic approach: where a court has issued a final judgment on the merits but erroneously assumed jurisdiction, relitigation may still …


Hindsight Is 20/20: Epilepsy Is Not One-Size-Fits-All, Raika Kim Apr 2025

Hindsight Is 20/20: Epilepsy Is Not One-Size-Fits-All, Raika Kim

Northwestern University Law Review

For many, epilepsy is one of the first conditions that come to mind when thinking of a disability, and for good reason: over 50 million people in the world live with epilepsy. Yet misunderstandings about epilepsy have perpetuated social stigma surrounding the disability for centuries. Ableist beliefs led to the passage of laws in the 1900s condoning—and in some cases, requiring—sterilization of individuals with epilepsy and restriction of their right to marry. Even today, state driving laws, justified as promoting public safety, categorically prevent anyone diagnosed with epilepsy from driving unless they are seizure free for an arbitrary, nonuniform period …


Let's Get Personal: Due Process And Personal Jurisdiction As A New Path Forward For Extraterritoriality, Samy Abdelsalam Apr 2025

Let's Get Personal: Due Process And Personal Jurisdiction As A New Path Forward For Extraterritoriality, Samy Abdelsalam

Northwestern University Law Review

The Supreme Court’s decision in Dobbs v. Jackson Women’s Health Organization has put fundamental principles of federalism and state sovereignty under attack. Legislation and lawsuits in states nationwide aim to limit the rights of American citizens to travel freely between states in search of medical care. Further, these measures have extraterritorial reach, legally entangling the rights of private citizens in other states who provide medical care even while fully within their own state borders. Scholars have analyzed this development through various doctrinal lenses, including the Dormant Commerce Clause. But these frameworks fail to adequately protect those who are unfortunate enough …