Open Access. Powered by Scholars. Published by Universities.®

Digital Commons Network™

Open Access. Powered by Scholars. Published by Universities.®

Discipline
Institution
Keyword
Publication Year
Publication
Publication Type
File Type

Articles 360001 - 360030 of 1195943

Full-Text Articles in Entire DC Network

A Brief Analysis Of Suicide Methods And Trends In Virginia From 2003 To 2012, Sameer Hassamal, Lori Keyser-Marcus, Ericka Crouse Breden, Kathrin Hobron, Atit Bhattachan, Ananda Pandurangi Jan 2015

A Brief Analysis Of Suicide Methods And Trends In Virginia From 2003 To 2012, Sameer Hassamal, Lori Keyser-Marcus, Ericka Crouse Breden, Kathrin Hobron, Atit Bhattachan, Ananda Pandurangi

Psychiatry Publications

Background. The objective is to analyze and compare Virginia suicide data from 2003 to 2012 to US suicide data. Methods. Suicide trends by method, age, gender, and race were obtained from Virginia’s Office of the Chief Medical Examiner’s annual reports. Results. Similar to US suicide rates, suicide rates in Virginia increased between 2003 and 2012 from 10.9/100,000 people to 12.9/100,000 people. The most common methods were firearm, asphyxia, and intentional drug overdose, respectively. The increase in asphyxia (𝑟 = 0.77, 𝑃 ≤ 0.01) and decrease in CO poisoning (𝑟 = −0.89, 𝑃 ≤ 0.01) were significant. Unlike national trends, intentional …

Go to article

Menorah Review (No. 83, Summer/Fall, 2015) Jan 2015

Menorah Review (No. 83, Summer/Fall, 2015)

Menorah Review

L’hitraot... -- A Model of Courage -- Books in Brief -- Compassion and Truth Meet (Psalm 85.11) -- Four Poems -- From the Classics -- Judaism and a Heliocentric Universe -- Two Essays by Peter Haas -- Zachor

Go to article

Chemokine Function In Periodontal Disease And Oral Cavity Cancer, Sinem Esra Sahingur, W. Andrew Yeudall Jan 2015

Chemokine Function In Periodontal Disease And Oral Cavity Cancer, Sinem Esra Sahingur, W. Andrew Yeudall

Periodontics Publications

The chemotactic cytokines, or chemokines, comprise a superfamily of polypeptides with a wide range of activities that include recruitment of immune cells to sites of infection and inflammation, as well as stimulation of cell proliferation. As such, they function as antimicrobial molecules and play a central role in host defenses against pathogen challenge. However, their ability to recruit leukocytes and potentiate or prolong the inflammatory response may have profound implications for the progression of oral diseases such as chronic periodontitis, where tissue destruction may be widespread. Moreover, it is increasingly recognized that chronic inflammation is a key component of tumor …

Go to article

Developmental Health Services Leadership: Integrating Hierarchical And Shared Leadership For Health Services Organizational Learning, Craig L. Pearce Jan 2015

Developmental Health Services Leadership: Integrating Hierarchical And Shared Leadership For Health Services Organizational Learning, Craig L. Pearce

CGU Faculty Publications and Research

The purpose of this article is to articulate a model of, as well as a call to action for, health services leadership, with a particular emphasis on the role of health services leadership in organizational learning. More specifically, I articulate a model that poses two antecedents of health services hierarchical leadership—leader responsibility disposition and environmental cues—as important predictors of empowering leadership. In turn, I assert that empowering leadership from above will engender an inclination toward shared leadership among followers. Subsequently, I venture that both empowering hierarchical leadership and shared leadership are precursors of health services organizational learning. I specify several …

Go to article

A Simple Method For Discovering Druggable, Specific Glycosaminoglycan-Protein Systems. Elucidation Of Key Principles From Heparin/Heparan Sulfate-Binding Proteins, Aurijit Sarkar, Umesh R. Desai Jan 2015

A Simple Method For Discovering Druggable, Specific Glycosaminoglycan-Protein Systems. Elucidation Of Key Principles From Heparin/Heparan Sulfate-Binding Proteins, Aurijit Sarkar, Umesh R. Desai

Medicinal Chemistry Publications

Glycosaminoglycans (GAGs) affect human physiology and pathology by modulating more than 500 proteins. GAG-protein interactions are generally assumed to be ionic and nonspecific, but specific interactions do exist. Here, we present a simple method to identify the GAG-binding site (GBS) on proteins that in turn helps predict high specific GAG–protein systems. Contrary to contemporary thinking, we found that the electrostatic potential at basic arginine and lysine residues neither identifies the GBS consistently, nor its specificity. GBSs are better identified by considering the potential at neutral hydrogen bond donors such as asparagine or glutamine sidechains. Our studies also reveal that an …

Go to article

Liberalis, Winter 2015, Utah State University Jan 2015

Liberalis, Winter 2015, Utah State University

Liberalis

Freedom to Think, Discover, and Create. The alumni magazine for the College of Humanities and Social Sciences at Utah State University.

Go to article

The Impact Of Mobbing And Job-Related Stress On Burnout And Health-Related Quality Of Life: The Case Of Turkish Territorial State Representatives, Mehmet Yesilbas Jan 2015

The Impact Of Mobbing And Job-Related Stress On Burnout And Health-Related Quality Of Life: The Case Of Turkish Territorial State Representatives, Mehmet Yesilbas

Electronic Theses and Dissertations

Job-related stress occurs as one of the most serious issues in modern era in developed nations. It has direct and negative effects on employees' productivity and it may have negative impacts on employees' health. One of the potential results of prolonged stressors at work place is burnout and this response may lead to physical, emotional, and psychological exhaustion that can occur at both individual and organizational levels. Burnout is a job related threat that provokes social stress and can directly affect an individual's health. Health-related quality of life (HRQoL) is commonly used to measure an individual's overall/global health and quality …

Go to article

Does Your Local Control Accountability (Lcap) Plan Deliver On The Promise Of Increased Or Improved Services For English Learners? 10 Research Aligned Rubrics To Help Answer The Question And Guide Your Program, Californians Together, The California Association For Bilingual Education (Cabe), California Rural Legal Assistance (Crla), The Center For Equity For English Learners (Ceel) Jan 2015

Does Your Local Control Accountability (Lcap) Plan Deliver On The Promise Of Increased Or Improved Services For English Learners? 10 Research Aligned Rubrics To Help Answer The Question And Guide Your Program, Californians Together, The California Association For Bilingual Education (Cabe), California Rural Legal Assistance (Crla), The Center For Equity For English Learners (Ceel)

Practitioner Journal Articles

As California’s Local Control Funding Formula (LCFF) came into effect in 2013, districts were given more flexibility to use state resources and create a new school finance system to improve/increase services for students with greater needs for support, including English Learners (ELs), students from low-income backgrounds, and foster youth. Local Education Agencies (LEAs) were tasked with preparing the Local Control and Accountability Plans (LCAPs) to describe how districts use their plans to meet their annual goals for all students. To aid LEAs in their design and implementation of programs to address the needs of ELs, Californians Together, the California Association …

Go to article

Cloud-Based Automated Design And Additive Manufacturing: A Usage Data-Enabled Paradigm Shift, Dirk Lehmhus, Thorsten Wuest, Stefan Wellsandt, Stefan Bosse, Toshiya Kaihara, Klaus-Dieter Thoben, Matthias Busse Jan 2015

Cloud-Based Automated Design And Additive Manufacturing: A Usage Data-Enabled Paradigm Shift, Dirk Lehmhus, Thorsten Wuest, Stefan Wellsandt, Stefan Bosse, Toshiya Kaihara, Klaus-Dieter Thoben, Matthias Busse

Faculty & Staff Scholarship

ntegration of sensors into various kinds of products and machines provides access to in-depth usage information as basis for product optimization. Presently, this large potential for more user-friendly and efficient products is not being realized because (a) sensor integration and thus usage information is not available on a large scale and (b) product optimization requires considerable efforts in terms of manpower and adaptation of production equipment. However, with the advent of cloud-based services and highly flexible additive manufacturing techniques, these obstacles are currently crumbling away at rapid pace. The present study explores the state of the art in gathering and …

Go to article

Transcriptome Assembly, Gene Annotation And Tissue Gene Expression Atlas Of The Rainbow Trout, Mohamed Salem, Bam Paneru, Rafet Al-Tobasei, Fatima Abdouni, Gary H. Thorgaard, Caird E. Rexroad, Jianbo Yao Jan 2015

Transcriptome Assembly, Gene Annotation And Tissue Gene Expression Atlas Of The Rainbow Trout, Mohamed Salem, Bam Paneru, Rafet Al-Tobasei, Fatima Abdouni, Gary H. Thorgaard, Caird E. Rexroad, Jianbo Yao

Faculty & Staff Scholarship

Efforts to obtain a comprehensive genome sequence for rainbow trout are ongoing and will be complemented by transcriptome information that will enhance genome assembly and annotation. Previously, transcriptome reference sequences were reported using data from different sources. Although the previous work added a great wealth of sequences, a complete and well-annotated transcriptome is still needed. In addition, gene expression in different tissues was not completely addressed in the previous studies. In this study, non-normalized cDNA libraries were sequenced from 13 different tissues of a single doubled haploid rainbow trout from the same source used for the rainbow trout genome sequence. …

Go to article

Just Because It's Legal Doesn't Mean You Can Do It: The Legality Of Employee Eavesdropping And Illinois Workplace Recording Policies, Michael J. Gibson Jan 2015

Just Because It's Legal Doesn't Mean You Can Do It: The Legality Of Employee Eavesdropping And Illinois Workplace Recording Policies, Michael J. Gibson

Loyola University Chicago Law Journal

In March 2014, in People v. Clark and People v. Melongo the Illinois Supreme Court held unconstitutional a large portion of the Illinois Eavesdropping Act (“IEA”), one of the nation’s strictest criminal eavesdropping statutes. However, on December 30, 2014, outgoing Governor Pat Quinn signed into law a new eavesdropping statute remedying what Clark and Melongo deemed unconstitutional. Prior to 2014, under the IEA, if employers caught employees recording conversations at work, the employer hardly needed a justification for employee discipline or discharge: the employee was violating the law. Thus, Clark, Melongo, and the December changes to the IEA raise questions …

Go to article

No Satisfaction: Italicized:Mellouli V. Lynch Rejects Deportation For Hidden Sock Pills, Thai-Binh H. Tran Jan 2015

No Satisfaction: Italicized:Mellouli V. Lynch Rejects Deportation For Hidden Sock Pills, Thai-Binh H. Tran

Loyola University Chicago Law Journal

No abstract provided.

Go to article

Congressional Dysfunction, Public Opinion, And The Battle Over The Keystone Xl Pipeline, Evan C. Zoldan Jan 2015

Congressional Dysfunction, Public Opinion, And The Battle Over The Keystone Xl Pipeline, Evan C. Zoldan

Loyola University Chicago Law Journal

When President Obama vetoed the Keystone XL Pipeline Approval Act in early 2015, he signaled the end of a political drama that pitted Congress against the President, Democrats against Republicans, and the promise of jobs against concern for the environment. Like most drama in Washington, it burned bright and hot, but soon was overtaken by other, suddenly more urgent, matters. Although news coverage of the pipeline has waned, the Keystone XL legislation represents the serious and enduring problem of congressional dysfunction. Using the Keystone XL legislation as a point of departure, this Article offers insights into the inner workings of …

Go to article

New Directions For Empirical Studies Of Direct Democracy, Joshua J. Dyck Jan 2015

New Directions For Empirical Studies Of Direct Democracy, Joshua J. Dyck

Chapman Law Review

No abstract provided.

Go to article

Rethinking The Tyranny Of The Majority: The Extra-Legal Consequences Of Anti-Gay Ballot Measures, Amy L. Stone Jan 2015

Rethinking The Tyranny Of The Majority: The Extra-Legal Consequences Of Anti-Gay Ballot Measures, Amy L. Stone

Chapman Law Review

No abstract provided.

Go to article

Town Of Tilton 2014 Annual Report., Tilton Town Representatives Jan 2015

Town Of Tilton 2014 Annual Report., Tilton Town Representatives

Tilton, NH Annual Reports

This is an annual report containing vital statistics for a town/city in the state of New Hampshire.

Go to article

Lessons From Institutional Shareholder Services: Governing Benefit Corporations' Third-Party Standard, Tammi S. Etheridge Jan 2015

Lessons From Institutional Shareholder Services: Governing Benefit Corporations' Third-Party Standard, Tammi S. Etheridge

Scholarly Articles

Third-party standard providers for benefit corporations will likely acquire the same level of success as Institutional Shareholder Services (ISS). Consequently, the public should be leery of encountering the same concerns, specifically, a lack of transparency, including undefined analytic models, inaccurate and incomplete information, and conflicts of interest. Going forward, the public should also be especially mindful of standard-providing organizations that also sell consulting services. As more states pass benefit corporation legislation, it is imperative that these issues be addressed and that solutions be proposed. Lax and uneven implementation of the third-party standard could mean that benefit corporation regulation, despite being …

Go to article

Minimum Information About A Biosynthetic Gene Cluster, M. H. Medema, R. Kottmann, P. Yilmaz, M. Cummings, J. B. Biggins, K. Blin, I. De Bruijn, Y. H. Chooi, J. Claesen, J. M. Willey, +144 Additional Authors Jan 2015

Minimum Information About A Biosynthetic Gene Cluster, M. H. Medema, R. Kottmann, P. Yilmaz, M. Cummings, J. B. Biggins, K. Blin, I. De Bruijn, Y. H. Chooi, J. Claesen, J. M. Willey, +144 Additional Authors

Journal Articles

No abstract provided.

Go to article

Notch Receptor Expression In Human Brain Arteriovenous Malformations, S. Hill-Felberg, H. H. Wu, S. A. Toms, A. R. Dehdashti Jan 2015

Notch Receptor Expression In Human Brain Arteriovenous Malformations, S. Hill-Felberg, H. H. Wu, S. A. Toms, A. R. Dehdashti

Journal Articles

The roles of the Notch pathway proteins in normal adult vascular physiology and the pathogenesis of brain arteriovenous malformations are not well-understood. Notch 1 and 4 have been detected in human and mutant mice vascular malformations respectively. Although mutations in the human Notch 3 gene caused a genetic form of vascular stroke and dementia, its role in arteriovenous malformations development has been unknown. In this study, we performed immunohistochemistry screening on tissue microarrays containing eight surgically resected human brain arteriovenous malformations and 10 control surgical epilepsy samples. The tissue microarrays were evaluated for Notch 1-4 expression. We have found that …

Go to article

Evaluating Blood-Brain Barrier Permeability In Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage, J. Ivanidze, K. Kesavabhotla, O. N. Kallas, D. Mir, H. Baradaran, A. Gupta, A. Z. Segal, J. Claassen, P. C. Sanelli Jan 2015

Evaluating Blood-Brain Barrier Permeability In Delayed Cerebral Infarction After Aneurysmal Subarachnoid Hemorrhage, J. Ivanidze, K. Kesavabhotla, O. N. Kallas, D. Mir, H. Baradaran, A. Gupta, A. Z. Segal, J. Claassen, P. C. Sanelli

Journal Articles

BACKGROUND AND PURPOSE: Patients with SAH are at increased risk of delayed infarction. Early detection and treatment of delayed infarction remain challenging. We assessed blood-brain barrier permeability, measured as permeability surface area product, by using CTP in patients with SAH with delayed infarction. MATERIALS AND METHODS: We performed a retrospective study of patients with SAH with delayed infarction on follow-up NCCT. CTP was performed before the development of delayed infarction. CTP data were postprocessed into permeability surface area product, CBF, and MTT maps. Coregistration was performed to align the infarcted region on the follow-up NCCT with the corresponding location on …

Go to article

Lithium In The Acute Treatment Of Bipolar I Disorder: A Double-Blind, Placebo-Controlled Study, R. L. Findling, A. Robb, N. K. Mcnamara, M. N. Pavuluri, V. Kafantaris, R. Scheffer, J. A. Frazier, M. Rynn, M. Delbello, R. A. Kowatch, B. M. Rowles, J. Lingler, K. Martz, R. Anand, T. E. Clemons, P. Taylor-Zapata Jan 2015

Lithium In The Acute Treatment Of Bipolar I Disorder: A Double-Blind, Placebo-Controlled Study, R. L. Findling, A. Robb, N. K. Mcnamara, M. N. Pavuluri, V. Kafantaris, R. Scheffer, J. A. Frazier, M. Rynn, M. Delbello, R. A. Kowatch, B. M. Rowles, J. Lingler, K. Martz, R. Anand, T. E. Clemons, P. Taylor-Zapata

Journal Articles

No abstract provided.

Go to article

Targeting Mutant Braf In Relapsed Or Refractory Hairy-Cell Leukemia, E. Tiacci, J. H. Park, L. De Carolis, S. S. Chung, A. Broccoli, S. Scott, F. Zaja, S. Devlin, K. R. Rai, M. S. Tallman, +31 Additional Authors Jan 2015

Targeting Mutant Braf In Relapsed Or Refractory Hairy-Cell Leukemia, E. Tiacci, J. H. Park, L. De Carolis, S. S. Chung, A. Broccoli, S. Scott, F. Zaja, S. Devlin, K. R. Rai, M. S. Tallman, +31 Additional Authors

Journal Articles

Background BRAF V600E is the genetic lesion underlying hairy-cell leukemia. We assessed the safety and activity of the oral BRAF inhibitor vemurafenib in patients with hairy-cell leukemia that had relapsed after treatment with a purine analogue or who had disease that was refractory to purine analogues. Methods We conducted two phase 2, single-group, multicenter studies of vemurafenib (at a dose of 960 mg twice daily) - one in Italy and one in the United States. The therapy was administered for a median of 16 weeks in the Italian study and 18 weeks in the U.S. STUDY: Primary end points were …

Go to article

Phase Ii Double-Blind Placebo-Controlled Randomized Study Of Armodafinil For Brain Radiation-Induced Fatigue, B. R. Page, E. G. Shaw, L. Lu, D. Bryant, D. Grisell, G. J. Lesser, D. C. Monitto, M. J. Naughton, S. R. Savona, M. D. Chan, +3 Additional Authors Jan 2015

Phase Ii Double-Blind Placebo-Controlled Randomized Study Of Armodafinil For Brain Radiation-Induced Fatigue, B. R. Page, E. G. Shaw, L. Lu, D. Bryant, D. Grisell, G. J. Lesser, D. C. Monitto, M. J. Naughton, S. R. Savona, M. D. Chan, +3 Additional Authors

Journal Articles

BACKGROUND: Common acute-term side effects of brain radiotherapy (RT) include fatigue, drowsiness, decreased physical functioning, and decreased quality of life (QOL). We hypothesized that armodafinil (a wakefulness-promoting drug known to reduce fatigue and increase cognitive function in breast cancer patients receiving chemotherapy) would result in reduced fatigue and sleepiness for patients receiving brain RT. METHODS: A phase II, multi-institutional, placebo-controlled randomized trial assessed feasibility of armodafinil 150 mg/day in participants receiving brain RT, from whom we obtained estimates of variability for fatigue, sleepiness, QOL, cognitive function, and treatment effect. RESULTS: From September 20, 2010, to October 20, 2012, 54 participants …

Go to article

Egfr And Her2: Is There A Role In Ovarian Cancer?, E. Teplinsky, F. Muggia Jan 2015

Egfr And Her2: Is There A Role In Ovarian Cancer?, E. Teplinsky, F. Muggia

Journal Articles

Advanced ovarian cancer carries a grim prognosis and development of targeted therapies to improve outcomes has become an active area of research in this disease. The epidermal growth factor receptor (EGFR) and HER2/neu have shown to be overexpressed in ovarian cancer and there have been several clinical trials evaluating anti-EGFR and HER2 therapies in ovarian cancer. Unfortunately, the drugs have shown minimal efficacy and more recent work has now focused on identifying mechanisms of resistance and alternative ways of targeting these pathways. This review will discuss the currently published trials with anti-EGFR and HER2 agents in ovarian cancer and the …

Go to article

Exon 4-Encoded Sequence Is A Major Determinant Of Cytotoxicity Of Apolipoprotein L1, A. K. Khatua, A. M. Cheatham, E. D. Kruzel, P. C. Singhal, K. Skorecki, W. Popik Jan 2015

Exon 4-Encoded Sequence Is A Major Determinant Of Cytotoxicity Of Apolipoprotein L1, A. K. Khatua, A. M. Cheatham, E. D. Kruzel, P. C. Singhal, K. Skorecki, W. Popik

Journal Articles

The apolipoprotein L1 (APOL1) gene (APOL1) product is toxic to kidney cells, and its G1 and G2 alleles are strongly associated with increased risk for kidney disease progression in African Americans. Variable penetrance of the G1 and G2 risk alleles highlights the significance of additional factors that trigger or modify the progression of disease. In this regard, the effect of alternative splicing in the absence or presence of G1 or G2 alleles is unknown. In this study we investigated whether alternative splicing of non-G1, non-G2 APOL1 (APOL1 G0) affects its biological activity. Among seven APOL1 exons, exons 2 and 4 …

Go to article

An Immunohistochemical Analysis Of Stathmin 1 Expression In Uterine Smooth Muscle Tumors: Differential Expression In Leiomyosarcomas And Leiomyomas, M. M. Allen, J. J. Douds, S. X. Liang, M. M. Desouki, V. Parkash, O. Fadare Jan 2015

An Immunohistochemical Analysis Of Stathmin 1 Expression In Uterine Smooth Muscle Tumors: Differential Expression In Leiomyosarcomas And Leiomyomas, M. M. Allen, J. J. Douds, S. X. Liang, M. M. Desouki, V. Parkash, O. Fadare

Journal Articles

The oncogenic phosphatidylinositol 3-kinase-AKT-mammlian target of rapamycin pathway (PI3K-AKT-mTOR) pathway is known to be activated in uterine smooth muscle tumors, and Stathmin 1 (STMN1) expression has been identified as a marker of PI3K-AKT-mTOR pathway activation. We hypothesized that STMN1 may have some diagnostic utility and explored how well STMN1 expression correlated with histologic classifications of uterine smooth muscle tumors into benign and malignant groupings. 84 smooth muscle tumors were assessed for STMN1 expression by immunohistochemistry. These included spindle cell leiomyosarcoma (n=32), conventional spindle cell leiomyomas (n=30), atypical (symplastic) leiomyoma (n=5), cellular leiomyoma (n=7), smooth muscle tumor of uncertain malignant potential …

Go to article

Exosomes In Cancer Research, S. R. Vaiselbuh Jan 2015

Exosomes In Cancer Research, S. R. Vaiselbuh

Journal Articles

No abstract provided.

Go to article

Mexican Immigrants As "Other": An Interdisciplinary Analysis Of U.S. Immigration Legislation And Political Cartoons, Olivia Teague Morgan Jan 2015

Mexican Immigrants As "Other": An Interdisciplinary Analysis Of U.S. Immigration Legislation And Political Cartoons, Olivia Teague Morgan

MA in English Theses

This paper uses postcolonial theory to analyze United States immigration legislation as it applies to the marginalized group of Mexican immigrants, beginning with the Treaty of Guadalupe Hidalgo in 1848 and ending with Obama’s proposed immigration plan in 2014. It also couples postcolonial theory with visual rhetoric concepts to analyze political cartoons and images relating to Mexican immigration, uncovering the attitudes and messages they represent.

Go to article

State Of New Hampshire Annual Report Of Coos County For The Year Ending December 31, 2014., Coos County Representatives Jan 2015

State Of New Hampshire Annual Report Of Coos County For The Year Ending December 31, 2014., Coos County Representatives

Coos County, NH Annual Reports

This is an annual report containing vital statistics for a county in the state of New Hampshire.

Go to article

Daily Soil Surface Co2 Flux During Non-Flooded Periods In Flood-Irrigated Rice Rotations, J. M. Motschenbacher, K. R. Brye, M. M. Anders, E. E. Gbur, N. A. Slaton, M. A. Evans-White Jan 2015

Daily Soil Surface Co2 Flux During Non-Flooded Periods In Flood-Irrigated Rice Rotations, J. M. Motschenbacher, K. R. Brye, M. M. Anders, E. E. Gbur, N. A. Slaton, M. A. Evans-White

School of Natural Resources: Faculty Publications

No abstract provided.

Go to article

First Prev Next Last