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The Role And Expression Of Pros-1 In The C. Elegans Gonad, Brandon W. Thomas, Mary B. Kroetz, Roberta Challener Apr 2025

The Role And Expression Of Pros-1 In The C. Elegans Gonad, Brandon W. Thomas, Mary B. Kroetz, Roberta Challener

Undergraduate Theses

The nematode, formally known as Caenorhabditis elegans, has served as an excellent model organism in understanding fundamental biological processes, including those governed by conserved genes like pros-1. pros-1 is partially responsible for the formation of tubular structures within the organism. Glial cells and excretory canals are both examples of tubular structures governed by pros-1. pros-1 orchestrates the embryonic development of these cell types by modulating cell proliferation and differentiation, thus ensuring proper morphogenesis and organogenesis. Its regulatory influence likely extends beyond embryogenesis, potentially affecting reproductive processes as well. Furthermore, the evolutionary conservation of pros-1 underscores its significance …


True Threats Of Coercive Control: Stalking Communications, Counterman V. Colorado, And The First Amendment, Myron Minn-Thu-Aye Apr 2025

True Threats Of Coercive Control: Stalking Communications, Counterman V. Colorado, And The First Amendment, Myron Minn-Thu-Aye

Seton Hall Law Review

No abstract provided.


Mcsa Forum Minutes 04/28/2025, Morris Campus Student Association Apr 2025

Mcsa Forum Minutes 04/28/2025, Morris Campus Student Association

Morris Campus Student Association

No abstract provided.


Cultivating Legal Protection: Replacing Wine Labeling Regulations With Regional Certification Marks, David Corasaniti Apr 2025

Cultivating Legal Protection: Replacing Wine Labeling Regulations With Regional Certification Marks, David Corasaniti

Washington and Lee Law Review Online

While wine labeling in the United States is currently governed by a complex regulatory framework administered by the Alcohol and Tobacco Tax and Trade Bureau (“TTB”), intellectual property (“IP”) rights for wine producing regions could serve this core function of protecting consumers better and more efficiently. Regulating wine labeling through IP would more closely mirror the system used by the European Union, which recognizes Geographical Indications, such as Champagne, Rioja, and Bordeaux, as a unique form of IP. By deregulating American wine labeling, and encouraging wine producing regions to assert their IP rights in the form of collectively held certification …


The Impact Of Erlinger V. United States On State Recidivist Sentencing Laws, Chad Flanders Apr 2025

The Impact Of Erlinger V. United States On State Recidivist Sentencing Laws, Chad Flanders

Washington and Lee Law Review Online

In Erlinger v. United States, the United States Supreme Court ruled that finding that an offender had committed two felonies “on separate occasions” under the Armed Career Criminal Act had to be done by a jury, not a judge. In one respect, the decision is narrow: it is an extension of the Court’s Apprendi jurisprudence. But in another respect, the decision is far-reaching. As some state appeals courts have already realized, the decision makes unconstitutional state laws that give the judge—rather than the jury—the power to decide whether someone is a “persistent” or “habitual” offender based on whether a …


Debtor's Adversary Re: State Court Litigation Apr 2025

Debtor's Adversary Re: State Court Litigation

Catholic Dioceses in Bankruptcy

No abstract provided.


Court's Order To Show Cause Re: Dismissal Apr 2025

Court's Order To Show Cause Re: Dismissal

Catholic Dioceses in Bankruptcy

No abstract provided.


"Nothing About Us Without Us": State-Level Disability Accommodation In The Wake Of The Ada, Megan F. Matteucci Apr 2025

"Nothing About Us Without Us": State-Level Disability Accommodation In The Wake Of The Ada, Megan F. Matteucci

Politics Honors Papers

The Americans with Disabilities Act (ADA) was passed in 1990 and protects people with disabilities (PWDs) from discrimination and includes provisions to make society more accommodating. The issue is that the ADA is federal legislation, but most of the implementation occurs at the state-level which means that some states are more accommodating than others. This project attempts to answer the following question: What factors contribute to the discrepancies in state-level disability policy and accommodation? It includes a quantitative study of all 50 states and investigates the impact of state income per capita, state partisanship, and business and disability interest group …


Border Restrictions In The Rise Of Anti-Immigration Politics, Katherine Hein Apr 2025

Border Restrictions In The Rise Of Anti-Immigration Politics, Katherine Hein

Politics Honors Papers

As anti-immigration sentiments have increased across the world, border restrictions have come under the spotlight from extremist right parties (ERPs). In a number of countries, ERPs are gaining support from their immigration rhetoric, which calls for heavily restricting or sometimes closing borders. This thesis examines the impact of restrictive border policies on support for anti-immigration platforms and ERPs. Using the Dataset of World Refugee and Asylum Policies Index and voting records of ERPs over time, a relationship between anti-immigration parties and border restrictions is hypothesized to produce one of three results: the more restrictive a border, the more likely an …


"Regarding" Thirty-Eight Months To Nowhere: The Need For Congressional Revision Of The Provisional Waiver Process, Omar A. Serrano Apr 2025

"Regarding" Thirty-Eight Months To Nowhere: The Need For Congressional Revision Of The Provisional Waiver Process, Omar A. Serrano

Seton Hall Law Review

No abstract provided.


Citizens United: The 2010 Crisis In The Marketplace Of Ideas, Abbagayle Grace Madanat Apr 2025

Citizens United: The 2010 Crisis In The Marketplace Of Ideas, Abbagayle Grace Madanat

Harriet L Wilkes Honors College Theses

In Citizens United v. FEC (2010), the Supreme Court ruled that corporations, like individuals, have First Amendment rights, enabling limitless corporate spending on political advocacy. This decision, made in the name of free speech, discounted concerns about corruption and destabilized the marketplace of ideas by granting corporations disproportionate influence and effectively drowning out citizens’ voices. I demonstrate how Citizens United deviated from legal precedents and the Framers' intentions for the First Amendment. Drawing from On Liberty, I argue that John Stuart Mill, one of history’s greatest free speech advocates, would have opposed the ruling, recognizing its distorting effects. I further …


Ndls Communicator: Week Of 04.28.25, Notre Dame Law School Apr 2025

Ndls Communicator: Week Of 04.28.25, Notre Dame Law School

NDLS Communicator

The Latest News

  • Notre Dame Law School Hosts Inaugural Affinity Alumni Reunion Weekend
  • Yusef Salaam shares message of justice, faith, and legacy at Notre Dame Law School
  • American Constitution Society selects ND Law's Varun Cidambi as a 2025 Next Generation Leader
  • Faculty profile: Professor Svitlana Khyliuk, leading expert in criminal justice and the European human rights system

Faculty Briefs

  • Last week, Paolo Carozza was interviewed by a variety of news outlets in connection with 11 new published decisions by the Meta Oversight Board.
  • Carter Snead appeared over the weekend on LiveNOW from FOX in a ten-minute interview about the direction …


Her Bun + My Oven = Our Child: Protecting The Legal Parentage Of Lgbtq+ Mothers And Their Children Conceived Via Reciprocal In Vitro Fertilization In Ohio, Courtney Hutchinson Apr 2025

Her Bun + My Oven = Our Child: Protecting The Legal Parentage Of Lgbtq+ Mothers And Their Children Conceived Via Reciprocal In Vitro Fertilization In Ohio, Courtney Hutchinson

Cleveland State Law Review

This Note discusses legal parentage in Ohio for two-women couples who expand their families via reciprocal in vitro fertilization or egg-sharing, where one woman is the genetic parent and the other is the gestational parent. Currently, the gestational mother is guaranteed legal parentage at the time of the child’s birth, while the genetic mother must petition the court for a formal adoption to protect her legal rights. A thorough review of court precedent regarding same-sex marriage makes clear that the public policy of Ohio permits two women to share in the legal rights of parentage. Furthermore, Ohio courts have regularly …


Courting Oblivion Part Ii: How To Revive American Reconstruction By Feigning Forgetfulness, Joshua J. Schroeder Apr 2025

Courting Oblivion Part Ii: How To Revive American Reconstruction By Feigning Forgetfulness, Joshua J. Schroeder

Cleveland State Law Review

This is the second part of the three-part Courting Oblivion series on the legal concept of oblivion, meaning legal forgetfulness, letting go of the past, or forgiveness usually to predicate a second chance, a restart, or even an era of reconstruction. This Article demonstrates how to apply the “right to move on” described in Part I to the law in the United States through acts of oblivion and amnesty. It describes the general uses of acts of oblivion and amnesty to the general framework of government in the United States, leading to the final discussion in Part III about the …


Evaluating Nature-Based Versus Generic Physical Activity Programs To Address Chronic Health Conditions: Lessons From An Oregon (Usa) Pilot Study, Randall Bluffstone, Ma Chan, Cort Cox, Melinda M. Davis, Caitlin Dickinson, Sahan T. M. Dissanayake, Jeffrey D. Kline, Himani Ojha, Sterling Stokes, Srilakshmi Vedantam, Multiple Additional Authors Apr 2025

Evaluating Nature-Based Versus Generic Physical Activity Programs To Address Chronic Health Conditions: Lessons From An Oregon (Usa) Pilot Study, Randall Bluffstone, Ma Chan, Cort Cox, Melinda M. Davis, Caitlin Dickinson, Sahan T. M. Dissanayake, Jeffrey D. Kline, Himani Ojha, Sterling Stokes, Srilakshmi Vedantam, Multiple Additional Authors

Economics Faculty Publications and Presentations

Evidence appears to be building that direct exposure to natural landscapes characterized by significant green cover, such as forests, can help to reduce chronic health conditions such as obesity, stress, hypertension, chronic cardiovascular conditions, depression, anxiety, cancer, and diabetes. One way to encourage greater exposure to nature may be through the use of nature prescriptions, whereby clinicians formally recommend (or prescribe) time in nature to their patients. Based on self-reported data, we describe the implementation and lessons learned from a pilot field experiment examining the clinical use of nature-based versus conventional exercise recommendations in rural Oregon. We discuss the potential …


What Are The Minimum Dimensions In A Marketing Plan Required For Starting Or Improving Marketing In A Small, New Home Health Agency?, Patrick Baker Apr 2025

What Are The Minimum Dimensions In A Marketing Plan Required For Starting Or Improving Marketing In A Small, New Home Health Agency?, Patrick Baker

MUSC Theses and Dissertations

Objective: To fulfill an unmet need for practical, parsimonious assistance for examples of a practical marketing plan for new, small home health care agencies. The home health (HH) care industry needs customized marketing plans tailored to the unique requirements of small, emerging HH agencies. These plans are essential for navigating the competitive market driven by an aging population and technological advancements. However, the industry's emphasis on this specific aspect is significantly lacking.

Methodology: We reviewed the published literature, numerous books and websites and selected sources that provided practical, small-scale approaches to marketing for health care organizations. We identified specific marketing …


How To Be Unique: A Guide To The Law School Admissions Process, Abigail E. Bjerke Apr 2025

How To Be Unique: A Guide To The Law School Admissions Process, Abigail E. Bjerke

Master's Projects

The law school admissions process can be a difficult thing to navigate, especially with updates that occur each year throughout the process. Therefore, this guide to law school admissions aims at making said admissions process easier to understand for all law school candidates. In the guide, there are several chapters regarding specific steps in the admissions process alongside an extended literature review of already existing guides or relevant articles.


Rural-Urban Disparities In Hospitalisation For Myocardial Infarction In Systemic Lupus Erythematosus In The Usa, Jasvinder A Singh, Sumanth Chandrupatla Apr 2025

Rural-Urban Disparities In Hospitalisation For Myocardial Infarction In Systemic Lupus Erythematosus In The Usa, Jasvinder A Singh, Sumanth Chandrupatla

Faculty, Staff and Students Publications

Objective: To assess whether rural-urban disparities exist in people with SLE for hospitalisation with myocardial infarction (MI).

Methods: We used the 2016-2019 US National Inpatient Sample data that contain all hospitalisation data. In people with a diagnosis of SLE, we assessed the multivariable adjusted ORs (aORs) to examine the association of rural patient residence with MI hospitalisation, while adjusting for demographics, payer, income, hospital characteristics and the Deyo-Charlson Comorbidity Index.

Results: We found that the crude rates of patients hospitalised with MI per 100 000 area specific SLE hospitalisations were higher in rural versus urban residents with SLE, 2265 versus …


The Effects Of Artificial Intelligence On Trial Courts, Alexys Zellner Apr 2025

The Effects Of Artificial Intelligence On Trial Courts, Alexys Zellner

Honors Projects

Artificial Intelligence has quickly entered the realm of everyday life. Without extensive testing, there have been issues surrounding transparency, accountability, and biased decisions made by Artificial Intelligence decision-making algorithms. When a political institution—such as the courts—uses these types of tools, there is a chance that the negative attributes will impact the institutions and actors using them. The court system relies on legitimacy and public approval to enforce its laws and decisions. This study aimed to determine whether the use of Artificial Intelligence would lead to a decrease in public approval and legitimacy of the courts, as well as diminish perceptions …


Sister, Lover, Monster: Gender, Sexuality, And Monstrousness In Batwoman, Carter Click Apr 2025

Sister, Lover, Monster: Gender, Sexuality, And Monstrousness In Batwoman, Carter Click

Honors Projects

Introduced in 2006, Kate Kane is the modern iteration of Batwoman, who is an out lesbian woman, in contrast to her 1950s counterpart that was created to alleviate concerns that Batman was gay. She would go on to star in stories by Greg Rucka, J.H. Williams III, and W. Haden Blackman that were published from 2009 to 2013. This run established core aspects of Kate’s character, supporting cast, and origin story. Though Rucka and Williams’ work has received some scholarly focus, Williams and Blackman’s work has received very little. This project attends to how these Batwoman comics facilitate queer representation …


Javier Milei, Fenómeno Barrial: Political Slogans As Narrative, Sawyer J. Deshon Apr 2025

Javier Milei, Fenómeno Barrial: Political Slogans As Narrative, Sawyer J. Deshon

Senior Honors Theses

Javier Milei won Argentina’s 2023 presidential race to the surprise of many. His prolific use of political slogans on social media has continued into his presidency, contextualizing his agenda and the potential image he seeks to project when pursuing reelection in 2027. This investigation conducts a critical reading of Javier Milei’s political slogans through the lens of Walter R. Fisher’s narrative paradigm, identifying a clear narrative arc that portrays Milei as a populist political outsider, villainizes the political elite of Argentina, and promises a thriving Argentina rooted in libertarian fiscal policy. The subsequent rhetorical analysis integrates quantitative and qualitative assessments …


Yoder In Brooklyn? Rapidly Expanding Free Exercise Jurisprudence, New York State School Regulations, And Hasidic Yeshivas, Jonathan Acampora Apr 2025

Yoder In Brooklyn? Rapidly Expanding Free Exercise Jurisprudence, New York State School Regulations, And Hasidic Yeshivas, Jonathan Acampora

Seton Hall Law Review

No abstract provided.


Unmasking Online Hostility: Analysing And Mitigating Hate Speech In Social Media, Jawaid Ahmed Siddiqui, Siti Sophiayati Yuhaniz, Zulfiqar Ali Memon Apr 2025

Unmasking Online Hostility: Analysing And Mitigating Hate Speech In Social Media, Jawaid Ahmed Siddiqui, Siti Sophiayati Yuhaniz, Zulfiqar Ali Memon

Baghdad Science Journal

The social media platforms have been generating an enormous amount of data for every second. Twitter, in practice by the individuals is producing more than six hundred tweets in each second. While freely posting opinions and expressions by users, it is very difficult to confine the hate speech shared against any individual, religion or any ethnic group. Consequently, the persons targeted by such hateful content get frustrated. In this regard the different approaches have been solving this serious problem but, sometimes unable to achieve satisfactory results. Therefore, we propose different Machine Learning models to classify given data in two categories, …


The Potential Of Brain Organoids In Addressing The Heterogeneity Of Synucleinopathies, Xiao-Jun Diao, Claudio Soto, Fei Wang, Yu Wang, Yun-Cheng Wu, Abhisek Mukherjee Apr 2025

The Potential Of Brain Organoids In Addressing The Heterogeneity Of Synucleinopathies, Xiao-Jun Diao, Claudio Soto, Fei Wang, Yu Wang, Yun-Cheng Wu, Abhisek Mukherjee

Faculty, Staff and Student Publications

Synucleinopathies are a group of diseases characterized by neuronal and glial accumulation of α-synuclein (aSyn) linked with different clinical presentations, including Parkinson's disease (PD), Parkinson's disease with dementia (PDD), Dementia with Lewy Bodies (DLB) and Multiple system atrophy (MSA). Interestingly, the structure of the aSyn aggregates can vary across different synucleinopathies. Currently, it is unclear how the aSyn protein can aggregate into diverse structures and affect distinct cell types and various brain regions, leading to different clinical symptoms. Recent advances in induced pluripotent stem cells (iPSCs)-based brain organoids (BOs) technology provide an unprecedented opportunity to define the etiology of synucleinopathies …


Whither Leviathan? The Seepage Of Constitutional Law Into Public-Private Arbitration In The United States, Peter B. Rutledge Apr 2025

Whither Leviathan? The Seepage Of Constitutional Law Into Public-Private Arbitration In The United States, Peter B. Rutledge

Scholarly Works

The chapter analyses how constitutional law influences private-public arbitration in the United States. Its central thesis is that constitutional law exerts a powerful indirect influence on arbitration law. While the US Constitution does not directly regulate arbitration, its underlying norms—such as separation of powers, federalism, and individual rights—impact arbitration law indirectly. The chapter explores the ways in which these constitutional principles influence public-private arbitration through statutory interpretation, treaty design, and private protocols reflecting constitutional norms. This pattern of influence manifests itself in public arbitration (i.e. arbitration involving states or state-owned entities) just as it does in private arbitration. Highlighting how …


The Impact Of Corruption On Lebanon's Governmental Institutions And The Connection To Terrorism, Joseph Mansour Apr 2025

The Impact Of Corruption On Lebanon's Governmental Institutions And The Connection To Terrorism, Joseph Mansour

Harriet L Wilkes Honors College Theses

This thesis explores how systemic corruption in Lebanon, deeply rooted in sectarian power structures and elite dominance, has eroded governance, exacerbated socioeconomic inequalities, and created vulnerabilities conducive to terrorism. Applying Dennis F. Thompson’s institutional theory of corruption alongside Seamus Miller’s normative and causal frameworks, I analyze how resource mismanagement, elite capture, and governance failures have degraded public trust and diminished state capacity. Drawing on empirical case studies—including the Beirut Port explosion, the failure of Electricité du Liban, and the manipulation of foreign aid—I demonstrate how corruption has weakened institutional legitimacy and contributed to national insecurity. The study concludes by advocating …


Multiracial, Interclass Democracy, Franciska Coleman Apr 2025

Multiracial, Interclass Democracy, Franciska Coleman

Seton Hall Law Review

No abstract provided.


The Battle For The Ballot In New Jersey, Eugene D. Mazo Apr 2025

The Battle For The Ballot In New Jersey, Eugene D. Mazo

Seton Hall Law Review

No abstract provided.


Essays In Macroeconomics, Manu Garcia Apr 2025

Essays In Macroeconomics, Manu Garcia

Arts & Sciences Graduate Student Theses and Dissertations

This dissertation is organized into three chapters, each offering novel insights into macroeconomic theory and practice. While the chapters address distinct phenomena, a common thread runs throughout: each study examines a transmission mechanism---whether of monetary shocks, normative change, or academic strategies---and underscores the importance of heterogeneity and dynamic adjustment in macroeconomic outcomes. In Chapter 1, I explore one of the most direct channels of monetary policy transmission---the refinancing window in the housing market. By exploiting comprehensive mortgage data from the Home Mortgage Disclosure Act (HMDA) spanning several decades, the analysis identifies episodes of heightened refinancing activity as quasi-natural experiments. Regions …


Quantifying Treatment Response To A Macrophage-Targeted Therapy In Combination With Immune Checkpoint Inhibitors After Exposure To Conventional Chemotherapy, Shelby N. Bess, Gaven K. Smart, Timothy J. Muldoon Apr 2025

Quantifying Treatment Response To A Macrophage-Targeted Therapy In Combination With Immune Checkpoint Inhibitors After Exposure To Conventional Chemotherapy, Shelby N. Bess, Gaven K. Smart, Timothy J. Muldoon

Biomedical Engineering Faculty Publications and Presentations

Background: Conventional chemotherapeutic agents, such as 5-fluorouracil (5-FU), can exert anti-tumor effects through immunogenic cell death (ICD) induction. Researchers have found hallmarks that quantify ICD (such as the translocation of HMGB1 and calreticulin). Although chemotherapeutic agents can induce ICD, they increase the expression of immune checkpoints, limiting their effectiveness. Studies have emphasized the importance of investigating the heterogeneous responses of cells co-localized in a solid tumor (macrophages, tumor cells, etc.) to ICD induction. However, these studies were performed in vivo, which limits the collection of information on cell-cell interactions due to model complexity.

Methods: In this study, we used a …