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Articles 31531 - 31560 of 1183368
Full-Text Articles in Entire DC Network
American Consumer Culture And Social Media Polarization: Analyzing Twentieth Century Trends And Their Effects On Twenty First Century Politics, Max Lally
University Honors Theses
The emergence of social media as a mainstream communication technology during the early twenty first century has had an outsized impact on the United States' political system. By analyzing trends in American culture and economics beginning in the decades following the end of World War Two, the circumstances that shaped social media during its development can be tied to long term historical changes. Shifts away from traditional models of community and towards rising individualism reshaped communication with both political allies and opponents. Generational shifts in political attitudes have heightened these divisions as well, as younger and liberal perspectives challenge traditional, …
A Postcolonial Re-Telling Of The Life And Times Of Dr. Bethenia Owens-Adair, Lucille Marie Walker
A Postcolonial Re-Telling Of The Life And Times Of Dr. Bethenia Owens-Adair, Lucille Marie Walker
University Honors Theses
This thesis seeks to explore the story of Dr. Bethenia Owens-Adair, one of the first female doctors in the Pacific Northwest, who wrote the bill that would one day enact Oregon's long standing eugenic sterilization laws. Utilizing postcolonial framework primarily provided by psychiatrist and political writer Frantz Fanon, and supplemental literature from historian Ann Stoler, this paper will look into Dr. Adair's life story and her eugenic efforts in an attempt to understand the colonial roots of turn-of-the-century beliefs about bodies, behavior, and will ultimately aim to question how these beliefs may still reverberate through society today.
Cll Cell-Derived Exosomes Alter The Immune And Hematopoietic Systems, Ivo Veletic, David M Harris, Uri Rozovski, Maria Teresa S Bertilaccio, George A Calin, Koichi Takahashi, Ping Li, Zhiming Liu, Taghi Manshouri, Rares-Constantin Drula, Ken Furudate, Muharrem Muftuoglu, Anwar Hossain, William G Wierda, Michael J Keating, Zeev Estrov
Cll Cell-Derived Exosomes Alter The Immune And Hematopoietic Systems, Ivo Veletic, David M Harris, Uri Rozovski, Maria Teresa S Bertilaccio, George A Calin, Koichi Takahashi, Ping Li, Zhiming Liu, Taghi Manshouri, Rares-Constantin Drula, Ken Furudate, Muharrem Muftuoglu, Anwar Hossain, William G Wierda, Michael J Keating, Zeev Estrov
Faculty, Staff and Student Publications
The origins of immunosuppression, neutropenia, and anemia in patients with chronic lymphocytic leukemia (CLL) are not fully understood. Because in patients with CLL, circulating exosomes, which participate in cell-to-cell interactions, are CLL cell-derived, we examined whether those exosomes contribute to abnormal features of this disease. Our data revealed that CLL cell-derived exosomes engulfed by healthy donors’ monocytes, fibrocytes, and lymphocytes altered target-cell gene and protein expression and suppressed normal hematopoiesis. CLL cell-derived exosomes increased normal monocytes’ CD14 and CD16 expression such that it mimicked the accessory cell profile and upregulated T cells’ checkpoint PD-1 and CD160 protein levels, potentially reducing …
International Expert-Based Consensus Definition, Classification Criteria, And Minimum Data Elements For Osteoradionecrosis Of The Jaw: An Interdisciplinary Modified Delphi Study, Amy C Moreno, Erin E Watson, Laia Humbert-Vidan, Douglas E Peterson, Lisanne V Van Dijk, Teresa Guerrero Urbano, Lisa Van Den Bosch, Andrew J Hope, Matthew S Katz, Frank J P Hoebers, Ruth A Aponte Wesson, James E Bates, Paolo Bossi, Adeyinka F Dayo, Mélanie Doré, Eduardo Rodrigues Fregnani, Thomas J Galloway, Daphna Y Gelblum, Issa A Hanna, Christina E Henson, Sudarat Kiat-Amnuay, Anke Korfage, Nancy Y Lee, Carol M Lewis, Charlotte Duch Lynggaard, Antti A Mäkitie, Marco Magalhaes, Yvonne M Mowery, Carles Muñoz-Montplet, Jeffrey N Myers, Ester Orlandi, Jaymit Patel, Jillian M Rigert, Deborah Saunders, Jonathan D Schoenfeld, Ugur Selek, Efsun Somay, Vinita Takiar, Juliette Thariat, Gerda M Verduijn, Alessandro Villa, Nicholas S West, Max J H Witjes, Alex M Won, Mark E Wong, Christopher M K L Yao, Simon W Young, Kamal Al-Eryani, Carly E A Barbon, Doke J M Buurman, François J Dieleman, Theresa M Hofstede, Abdul Ahad Khan, Adegbenga O Otun, John C Robinson, Lauren Hum, Jorgen Johansen, Rajesh Lalla, Alexander Lin, Vinod Patel, Richard J Shaw, Mark S Chambers, Daniel Ma, Mabi Singh, Noam Yarom, Abdallah Sherif Radwan Mohamed, Katherine A Hutcheson, Stephen Y Lai, Clifton David Fuller
International Expert-Based Consensus Definition, Classification Criteria, And Minimum Data Elements For Osteoradionecrosis Of The Jaw: An Interdisciplinary Modified Delphi Study, Amy C Moreno, Erin E Watson, Laia Humbert-Vidan, Douglas E Peterson, Lisanne V Van Dijk, Teresa Guerrero Urbano, Lisa Van Den Bosch, Andrew J Hope, Matthew S Katz, Frank J P Hoebers, Ruth A Aponte Wesson, James E Bates, Paolo Bossi, Adeyinka F Dayo, Mélanie Doré, Eduardo Rodrigues Fregnani, Thomas J Galloway, Daphna Y Gelblum, Issa A Hanna, Christina E Henson, Sudarat Kiat-Amnuay, Anke Korfage, Nancy Y Lee, Carol M Lewis, Charlotte Duch Lynggaard, Antti A Mäkitie, Marco Magalhaes, Yvonne M Mowery, Carles Muñoz-Montplet, Jeffrey N Myers, Ester Orlandi, Jaymit Patel, Jillian M Rigert, Deborah Saunders, Jonathan D Schoenfeld, Ugur Selek, Efsun Somay, Vinita Takiar, Juliette Thariat, Gerda M Verduijn, Alessandro Villa, Nicholas S West, Max J H Witjes, Alex M Won, Mark E Wong, Christopher M K L Yao, Simon W Young, Kamal Al-Eryani, Carly E A Barbon, Doke J M Buurman, François J Dieleman, Theresa M Hofstede, Abdul Ahad Khan, Adegbenga O Otun, John C Robinson, Lauren Hum, Jorgen Johansen, Rajesh Lalla, Alexander Lin, Vinod Patel, Richard J Shaw, Mark S Chambers, Daniel Ma, Mabi Singh, Noam Yarom, Abdallah Sherif Radwan Mohamed, Katherine A Hutcheson, Stephen Y Lai, Clifton David Fuller
Faculty, Staff and Student Publications
Purpose: Osteoradionecrosis of the jaw (ORNJ) is a severe iatrogenic disease characterized by bone death after radiation therapy to the head and neck. With >9 published definitions and at least 16 classification systems, the true incidence and severity of ORNJ are obscured by lack of a standard for disease definition and severity assessment, leading to inaccurate estimation of incidence, reporting ambiguity, and likely underdiagnosis worldwide. This study aimed to achieve consensus on an explicit definition and phenotype of ORNJ and related precursor states through data standardization to facilitate effective diagnosis, monitoring, and multidisciplinary management of ORNJ.
Methods and materials: The …
International Multidisciplinary Consensus Recommendations On Clinical Application Of Three-Dimensional Visualization In Precision Surgery For Pediatric Liver Tumors, Qian Dong, Wenli Xiu, Benjie Tang, Eiso Hiyama, Mary T Austin, Yeming Wu, Xiaojun Yuan, Chengzhan Zhu, Chengli Liu, Hiroki Ishibashi, Karthik K Tappa, Huanmin Wang, Chuandong Sun, Yuntao Ma, Hongwei Xi, Jian Wang, Jianghua Zhan, Kyong Ihn, Mitsuo Shimada, Mingman Zhang, Mary E Brindle, Patrick B Thomas, Shigehisa Fumino, Tao Liu, Thom Lobe, Udo Rolle, Shan Wang, Xiaowen Zhai, Yoshinori Koga, Yoshiaki Kinoshita, Yuzuo Bai, Zhaozhu Li, Zhe Wen, Weikang Pan, Krysta M Sutyak, Pier C Giulianotti
International Multidisciplinary Consensus Recommendations On Clinical Application Of Three-Dimensional Visualization In Precision Surgery For Pediatric Liver Tumors, Qian Dong, Wenli Xiu, Benjie Tang, Eiso Hiyama, Mary T Austin, Yeming Wu, Xiaojun Yuan, Chengzhan Zhu, Chengli Liu, Hiroki Ishibashi, Karthik K Tappa, Huanmin Wang, Chuandong Sun, Yuntao Ma, Hongwei Xi, Jian Wang, Jianghua Zhan, Kyong Ihn, Mitsuo Shimada, Mingman Zhang, Mary E Brindle, Patrick B Thomas, Shigehisa Fumino, Tao Liu, Thom Lobe, Udo Rolle, Shan Wang, Xiaowen Zhai, Yoshinori Koga, Yoshiaki Kinoshita, Yuzuo Bai, Zhaozhu Li, Zhe Wen, Weikang Pan, Krysta M Sutyak, Pier C Giulianotti
Faculty, Staff and Student Publications
Background: Pediatric liver tumors are predominantly primary malignant tumors, and complete tumor resection with sufficient preservation of liver tissue is crucial for improving prognosis. However, due to the delicate anatomical structure of the pediatric liver and the relatively large size of the tumors, especially in difficult cases, the surgical challenges are substantial. While precision liver surgery are widely applied in clinical practice, pediatric cases require more customized approaches. The application of three-dimensional (3D) visualization technology is crucial for enhancing surgical accuracy, allowing for precise preoperative planning and intraoperative guidance.
Methods: This consensus was collaboratively developed by 36 experts from eight …
Association Of Sirt6 Expression With Risk Of Pneumonitis Induced By Radiotherapy In Cancer Patients, Fengyuan Yu, Zheng Gong, Yuan Li, Danial F Naseem, Chen Li, Miaowei Wen, Bingying Zhao, Zhezhe Xu, Shanshan Zhang, Rukun Zang, Ailu Wu, Qingxin Han, Shuhui Wu, Hongwei Li, Yipeng Song
Association Of Sirt6 Expression With Risk Of Pneumonitis Induced By Radiotherapy In Cancer Patients, Fengyuan Yu, Zheng Gong, Yuan Li, Danial F Naseem, Chen Li, Miaowei Wen, Bingying Zhao, Zhezhe Xu, Shanshan Zhang, Rukun Zang, Ailu Wu, Qingxin Han, Shuhui Wu, Hongwei Li, Yipeng Song
Faculty, Staff and Student Publications
Thoracic tumours represent a significant proportion of malignant cancers. While radiotherapy (RT) improves prognosis, it can also lead to side effects such as radiation-induced pneumonitis (RP). Since SIRT6 is involved in DNA repair, energy metabolism and inflammation, this study aims to investigate the expression of SIRT6 in lymphocytes as a potential biomarker and therapeutic target for RP. This study included 170 patients diagnosed with thoracic tumours, all of whom underwent thoracic RT. RP was evaluated and classified as severe RP (SRP) and lower as non-severe RP (NSRP). Analyses were performed using SPSS version 26.0 and the R. Among 170 patients …
Therapeutic Hurdles In Acute Myeloid Leukemia: Leukemic Stem Cells, Inflammation And Immune Dysfunction, Bofei Wang, Patrick K Reville, Hussein A Abbas
Therapeutic Hurdles In Acute Myeloid Leukemia: Leukemic Stem Cells, Inflammation And Immune Dysfunction, Bofei Wang, Patrick K Reville, Hussein A Abbas
Faculty, Staff and Student Publications
Acute myeloid leukemia (AML) is an aggressive and highly heterogeneous hematological malignancy characterized by clonal expansion and differentiation arrest in myeloid progenitor cells. Despite advancements in chemotherapy, allogeneic hematopoietic stem cell transplantation, and post-remission maintenance therapies, the long-term survival remains unsatisfactory with high rates of relapse and refractory. These therapeutic challenges are mediated by multiple factors, including the complexity of the cellular hierarchies in AML, the interaction of leukemic stem cells (LSCs) with the bone marrow niche, inflammation, and immune evasion mechanisms. Further, the absence of specific surface markers that distinguish LSCs from normal hematopoietic stem cells, together with LSCs' …
Clinical Interrogation Of Tp53 Aberrations And Its Impact On Survival In Patients With Myeloid Neoplasms, Jayastu Senapati, Sanam Loghavi, Guillermo Garcia-Manero, Guillin Tang, Tapan Kadia, Nicholas J Short, Hussein A Abbas, Naszrin Arani, Courtney D Dinardo, Gautam Borthakur, Naveen Pemmaraju, Betul Oran, Elizabeth Shpall, Uday Popat, Richard Champlin, Sherry Pierce, Sankalp Arora, Ghayas Issa, Musa Yilmaz, Keyur Patel, Koichi Takahashi, Guillermo Montalban-Bravo, Danielle Hammond, Fadi G Haddad, Farhad Ravandi, Hagop M Kantarjian, Naval G Daver
Clinical Interrogation Of Tp53 Aberrations And Its Impact On Survival In Patients With Myeloid Neoplasms, Jayastu Senapati, Sanam Loghavi, Guillermo Garcia-Manero, Guillin Tang, Tapan Kadia, Nicholas J Short, Hussein A Abbas, Naszrin Arani, Courtney D Dinardo, Gautam Borthakur, Naveen Pemmaraju, Betul Oran, Elizabeth Shpall, Uday Popat, Richard Champlin, Sherry Pierce, Sankalp Arora, Ghayas Issa, Musa Yilmaz, Keyur Patel, Koichi Takahashi, Guillermo Montalban-Bravo, Danielle Hammond, Fadi G Haddad, Farhad Ravandi, Hagop M Kantarjian, Naval G Daver
Faculty, Staff and Student Publications
In myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML) with TP53 aberrations, dissecting the interaction amongst patient, disease and treatment factors are important for therapeutic decisions and prognostication. This retrospective analysis included patients with newly diagnosed MDS (>5% blasts) and AML with TP53 mutation(s) treated at MD Anderson Cancer Center. We factored patient age, TP53 aberration burden, therapy intensity and use of venetoclax in the AML subgroup, and allogeneic hematopoietic stem cell transplantation (HSCT) to interrogate outcomes. TP53 was annotated as high-risk (TP53HR) if >1 mutation, one mutation plus allelic deletion or a single mutation with variant allele frequency …
Egfr Controls Transcriptional And Metabolic Rewiring In Krasg12d Colorectal Cancer, Dana Krauß, Veronica Moreno-Viedma, Emi Adachi-Fernandez, Cristiano De Sá Fernandes, Jakob-Wendelin Genger, Ourania Fari, Bernadette Blauensteiner, Dominik Kirchhofer, Nikolina Bradaric, Valeriya Gushchina, Georgios Fotakis, Thomas Mohr, Ifat Abramovich, Inbal Mor, Martin Holcmann, Andreas Bergthaler, Arvand Haschemi, Zlatko Trajanoski, Juliane Winkler, Eyal Gottlieb, Maria Sibilia
Egfr Controls Transcriptional And Metabolic Rewiring In Krasg12d Colorectal Cancer, Dana Krauß, Veronica Moreno-Viedma, Emi Adachi-Fernandez, Cristiano De Sá Fernandes, Jakob-Wendelin Genger, Ourania Fari, Bernadette Blauensteiner, Dominik Kirchhofer, Nikolina Bradaric, Valeriya Gushchina, Georgios Fotakis, Thomas Mohr, Ifat Abramovich, Inbal Mor, Martin Holcmann, Andreas Bergthaler, Arvand Haschemi, Zlatko Trajanoski, Juliane Winkler, Eyal Gottlieb, Maria Sibilia
Faculty, Staff and Student Publications
Inhibition of the epidermal growth factor receptor (EGFR) shows clinical benefit in metastatic colorectal cancer (CRC) patients, but KRAS-mutations are known to confer resistance. However, recent reports highlight EGFR as a crucial target to be co-inhibited with RAS inhibitors for effective treatment of KRAS mutant CRC. Here, we investigated the tumor cell-intrinsic contribution of EGFR in KRASG12D tumors by establishing murine CRC organoids with key CRC mutations (KRAS, APC, TP53) and inducible EGFR deletion. Metabolomic, transcriptomic, and scRNA-analyses revealed that EGFR deletion in KRAS-mutant organoids reduced their phenotypic heterogeneity and activated a distinct cancer-stem-cell/WNT signature associated with reduced cell size …
Nlrp3 Inflammasome Activation Expands The Immunosuppressive Myeloid Stroma And Antagonizes The Therapeutic Benefit Of Sting Activation In Glioblastoma, Spencer T Lea, Chao-Hsien Chen, Jun Wei, Ivana William, Inés Lopez Del Castillo, Michael A Curran
Nlrp3 Inflammasome Activation Expands The Immunosuppressive Myeloid Stroma And Antagonizes The Therapeutic Benefit Of Sting Activation In Glioblastoma, Spencer T Lea, Chao-Hsien Chen, Jun Wei, Ivana William, Inés Lopez Del Castillo, Michael A Curran
Faculty, Staff and Student Publications
Glioblastoma (GBM) is the most common and deadly primary brain malignancy and is clinically refractory to immunotherapy. Active NLRP3 inflammasome signaling and IL-1β secretion have been observed in GBM, and NLRP3-driven myeloid-derived suppressor cell (MDSC) recruitment can mediate cancer immune evasion. Agonists of the cytosolic double-stranded DNA-sensing stimulator of IFN gene (STING) pathway can mediate proinflammatory conversion of cancer MDSCs; however, secretion of the NLRP3 products IL-1β and IL-18 has also been observed in certain myeloid populations following STING activation. In this study, we aimed to determine both the potential mechanistic synergy between STING and NLRP3 agonists, and the effects …
Head Of Roses, Remy Levine
Head Of Roses, Remy Levine
University Honors Theses
Head of Roses is a slow-burn religious horror novel, the first five chapters of which constitute this thesis project. In order to examine its themes -- that of grief and trauma, guilt and shame, motherhood, religion and faith, and the redemptive power of love -- the novel carefully subverts religious horror genre conventions regarding the traditional roles of protagonist and site of horror. Head of Roses deconstructs these genre archetypes with an inverted narrative: the protagonist inadvertently produces the horrific element and the religious institution become the victims. Rather than addressing tensions in faith through demonic or occult subject material, …
"It Had To Stop": Content Analysis Of Fox News Library Censorship Discourse, Lex Faller
"It Had To Stop": Content Analysis Of Fox News Library Censorship Discourse, Lex Faller
University Honors Theses
Library censorship poses a threat to inclusive communities by foreclosing the possibility of finding diverse representations through media. Certain demographics are more dependent on libraries for media access than others. Censorship is therefore especially concerning for those who cannot purchase media or afford subscriptions themselves. The most vocal proponents of contemporary library censorship are ideologically conservative; therefore, conservative media ecosystems play a key role in library censorship discourse. Fox News television is the most watched television news channel by a wide margin in the U.S. and therefore has an outsized influence on U.S. adults. This research involved a qualitative content …
The Association Between Different Succession Methods And Innovation Investments In Family Businesses In China, Lei Wu
Dissertations and Theses Collection (Open Access)
Amidst the deepening of economic globalization, countries around the world are being progressively steered toward paths of innovative development, laying a solid foundation for enhancing national comprehensive strength and elevating international standing. Especially after the implementation of the reform and opening-up policy in our country, technological innovation has become the main direction of our transformation. According to the requirements of the 20th National Congress of the Communist Party of China, innovation-driven development will be fully applied to the country's development, creating favorable conditions for the realization of strategic development goals. National development and social progress are directly linked to corporate …
The Rose That Grew From Concrete: Exploring The Romantic Experiences Of Black Men With Histories Of Childhood Sexual Abuse, Tatyana Nichelle Smith
The Rose That Grew From Concrete: Exploring The Romantic Experiences Of Black Men With Histories Of Childhood Sexual Abuse, Tatyana Nichelle Smith
Dissertations
Contemporary research typically characterizes Black heterosexual relationships by dismal marriage and divorce rates, largely ignoring the reality of how Black men develop attachments with their romantic partners and therefore continuing to perpetuate deficit perspectives of Black men (e.g., the cause of conflictual romantic relationships and “broken” Black families). What may be less understood about these relationships is the influence of childhood trauma, such as childhood sexual abuse, and Black men’s experiences of gender role conflict. Research shows that Black men’s experiences of childhood sexual abuse and socialization about masculinity have important implications for how they come to view themselves and …
Pension Participation Among Different Migrant Groups In China: Job Type, Regional Disparities, And Cross-Provincial Mobility, Boxia Xu
Dissertations
As China undergoes rapid economic transformation and urbanization, the migrant population has grown significantly. Although migrants play essential roles in the labor market, they face persistent structural barriers to pension access. Regional disparities, occupational segmentation, and cross-provincial mobility constraints affect the probability of their pension participation. While policy efforts aim to expand coverage, the fragmented nature of China’s pension system continues to hinder equitable access for migrants. As a result, ensuring pension participation among migrant groups remains a pressing challenge.
Using data from the 2014 China Migrants Dynamic Survey (CMDS), this dissertation employs logistic regression models to investigate how job …
Identifying Perceived Barriers In Special Education, Alexus K. Wilson
Identifying Perceived Barriers In Special Education, Alexus K. Wilson
Electronic Theses and Dissertations
This study explored the lived experiences of teachers and administrators supporting students with disabilities transitioning from special education to general education settings. Grounded in a phenomenological approach within a qualitative research paradigm, the research aimed to uncover how educators perceive and navigate the challenges, barriers, and successes associated with this complex transition process. Data were collected through semistructured interviews with a purposive sample of special education teachers, general education teachers, and school administrators from a small urban district in Texas. The study followed a qualitative methodology that focused on transition theory, and data were analyzed using thematic analysis.The research procedures …
Filling The Sackett Gap: The Private Governance Option, Michael P. Vandenbergh, Elodie O. Currier Stoffel, Steph Tai
Filling The Sackett Gap: The Private Governance Option, Michael P. Vandenbergh, Elodie O. Currier Stoffel, Steph Tai
Vanderbilt Law School Faculty Publications
The Supreme Court's decision in Sackett v. EPA reversed fifty years of federal Clean Water Act wetlands protections and removed federal oversight from roughly half of the wetlands in the United States. This Article proposes a viable new conceptual model and tools to close the Sackett Gap-the gap between the wetlands protected before and after Sackett. Scholars have argued for federal measures to fill the Sackett Gap, but these actions face substantial challenges. Congress is unlikely to adopt new wetlands legislation, agencies are constrained by Sackett's expansive language, the end of Chevron deference, and the 2024 presidential election, and lower …
Thermal Modeling Techniques For Additively Manufactured Porous Metals, Lucas D. Rambo
Thermal Modeling Techniques For Additively Manufactured Porous Metals, Lucas D. Rambo
Master's Theses
Advances in additive manufacturing have enabled the creation of metallic components with tailored porosity, offering design flexibility for thermal, structural, and fluid transport applications. This thesis investigates the effective thermal conductivity (ETC) of porous Inconel 625 (IN625) and Inconel-ceramic composites (IN625-RAM2) fabricated by Laser Powder Bed Fusion (LPBF) using Elementum 3D’s PermiAM technology. Experimental measurements of thermal conductivity using the laser flash method are compared to numerical models built from micro-computed tomography data. Simulations were performed using both finite element (FE) and finite volume (FV) methods to evaluate thermal transport in real microstructures. The study investigates the effects of micro- …
Chatgpt On Chatgpt: An Exploratory Analysis Of Its Performance In The Public Sector Workplace, Jieshu Wang, Elif Kiran, S. R. Aurora, Michael Simeone, Jose Lobo
Chatgpt On Chatgpt: An Exploratory Analysis Of Its Performance In The Public Sector Workplace, Jieshu Wang, Elif Kiran, S. R. Aurora, Michael Simeone, Jose Lobo
Management Faculty Publications
This study explores the impact of Generative Artificial Intelligence (GenAI), in particular, ChatGPT, on the public sector workforce in the United States, focusing on task replacement, assistance potential, and the evolving landscape of skills. Utilizing GPT-4 to evaluate 1,022 core tasks across 51 public sector occupations, we provide an exploratory analysis of the roles susceptible to ChatGPT automation and those in which ChatGPT can augment human efforts. Our findings reveal that while 63% of tasks are resistant to ChatGPT replacement, primarily due to their requirement for physical presence, emotional intelligence, and complex decision-making, tasks that are routine, rule-based, and involving …
A Summoned Life: Vocation In The Analects, Teng-Kuan Ng
A Summoned Life: Vocation In The Analects, Teng-Kuan Ng
Research Collection College of Integrative Studies
This article explores the concept of vocation in the Analects. While most treatmentsof vocation focus on the Christian tradition, and while Confucian thought is oftenviewed as categorically nontheistic, Robert Merrihew Adams’s Finite and InfiniteGoods (1999) presents an illuminating comparative framework for tracing outKongzi’s religious ethical vision of how persons think, act, and feel when graspedby a sense of divine calling. I argue that in the Analects a vocation is compositelyconceived as: (1) a special divine imperative to an individual or a community (2) tolove particular goods within one’s actual circumstances (3) with nonconsequentialist,noncompetitive, and potentially counter-cultural commitment (4) such that …
Experimental And Computational Study Of Slow Crack Growth Of High Density Polyethylene, Abdulla Fawzi Almomani
Experimental And Computational Study Of Slow Crack Growth Of High Density Polyethylene, Abdulla Fawzi Almomani
Dissertations
This dissertation investigates the slow crack growth (SCG) behavior of High-Density Polyethylene (HDPE) under various mechanical and environmental conditions. The study combines experimental analysis and computational modeling to enhance the understanding of SCG mechanisms in HDPE, particularly in pressurized pipes and under the exposure to hydrocarbons. A novel Crack Layer (CL) theory-based SCG model is developed and validated through experimental data, offering a predictive framework for HDPE failure assessment. The main objective of this dissertation is to quantify and model the viscoelastic-viscoplastic behavior of HDPE under monotonic and cyclic loading conditions while addressing SCG kinetics in structural applications. The study …
Validity And Reliability Of The Tampa Scale For Kinesiophobia For Adolescents With Heart Disease., David A. White, William R. Black, Emily Cramer, Lindsey Malloy-Walton, Mollie Walton, Laura Martis, Brandy Enneking, Kelli M. Teson, Jessica S. Watson, Jami Gross-Toalson
Validity And Reliability Of The Tampa Scale For Kinesiophobia For Adolescents With Heart Disease., David A. White, William R. Black, Emily Cramer, Lindsey Malloy-Walton, Mollie Walton, Laura Martis, Brandy Enneking, Kelli M. Teson, Jessica S. Watson, Jami Gross-Toalson
Manuscripts, Articles, Book Chapters and Other Papers
PURPOSE: To assess the validity and reliability of a newly adapted Tampa Scale for KP for adolescents with HD (TSK-Heart-A).
METHODS: The TSK-Heart-A survey consists of 17 Likert scale items, producing a summary score (SS) ranging from 17 (low KP) to 68 (high KP). Following content and face validity, adolescents (age 12-18 yr) with arrhythmia disorders or Fontan palliation were recruited. The PROMIS pediatric anxiety and depression short forms, Pediatric Quality of Life Inventory (PedsQL) generic core and cardiac module, and a PA questionnaire for adolescents (PAQ-A) were used for criterion validity. The TSK-Heart-A was completed twice (20.4 ± 6.3 …
Revisiting “Mandatory Mediation: An Oxymoron?” Advancing Access To Civil Justice Through Mandatory Adr, Dorcas Quek Anderson
Revisiting “Mandatory Mediation: An Oxymoron?” Advancing Access To Civil Justice Through Mandatory Adr, Dorcas Quek Anderson
Research Collection Yong Pung How School Of Law
Access to civil justice, a concept integral to the rule of law, has been an enduring concern in many countries. One prominent strategy to enhance access to civil justice entails the use of alternative dispute resolution (ADR) methods prior to court adjudication. In this regard, efforts to embed ADR within the court system have intensified in both England and Wales and Singapore. In Singapore, the parties have a duty to consider ADR prior to and during civil proceedings. More significantly, the courts have been empowered to order parties to attempt ADR. In a similar vein, the English Court of Appeal …
Treaties Establishing Dispute Settlement Frameworks, N. Jansen Calamita, Stefanie Schacherer, Facundo Perez-Aznar, Aikaterini Florou
Treaties Establishing Dispute Settlement Frameworks, N. Jansen Calamita, Stefanie Schacherer, Facundo Perez-Aznar, Aikaterini Florou
Research Collection Yong Pung How School Of Law
The purpose of the present report is to provide an overview and analysis of the measures that States adopt domestically to implement treaties that establish mechanisms for the resolution of international disputes. The report’s scope subsumes both treaties that include dispute settlement mechanisms to resolve disputes concerning the substantive obligations contained therein as well as treaties that establish frameworks for dispute resolution simpliciter which may be used to resolve disputes arising under a variety of substantive treaties (collectively “international dispute settlement mechanism” or “IDSM” treaties). The approach of the research contained within this report has been to gather information about …
Large Language Model For Vulnerability Detection And Repair: Literature Review And The Road Ahead, Xin Zhou, Sicong Cao, Xiaobing Sun, David Lo
Large Language Model For Vulnerability Detection And Repair: Literature Review And The Road Ahead, Xin Zhou, Sicong Cao, Xiaobing Sun, David Lo
Research Collection School Of Computing and Information Systems
The significant advancements in Large Language Models (LLMs) have resulted in their widespread adoption across various tasks within Software Engineering (SE), including vulnerability detection and repair. Numerous studies have investigated the application of LLMs to enhance vulnerability detection and repair tasks. Despite the increasing research interest, there is currently no existing survey that focuses on the utilization of LLMs for vulnerability detection and repair. In this paper, we aim to bridge this gap by offering a systematic literature review of approaches aimed at improving vulnerability detection and repair through the utilization of LLMs. The review encompasses research work from leading …
A Knowledge Enhanced Large Language Model For Bug Localization, Yue Li, Bohan Liu, Ting Zhang, Zhiqi Wang, David Lo, Lanxin Yang, Jun Lyu, He Zhang
A Knowledge Enhanced Large Language Model For Bug Localization, Yue Li, Bohan Liu, Ting Zhang, Zhiqi Wang, David Lo, Lanxin Yang, Jun Lyu, He Zhang
Research Collection School Of Computing and Information Systems
A significant number of bug reports are generated every day as software systems continue to develop. Large Language Models (LLMs) have been used to correlate bug reports with source code to locate bugs automatically. The existing research has shown that LLMs are effective for bug localization and can increase software development efficiency. However, these studies still have two limitations. First, these models fail to capture context information about bug reports and source code. Second, these models are unable to understand the domain-specific expertise inherent to particular projects, such as version information in projects that are composed of alphanumeric characters without …
Unlocking The Power Of Socio-Knowledge Association For Enterprise Risk Identification In Stock Market, Zhenghao Liu, Keng Siau, Shaochen Yang, Feicheng Ma
Unlocking The Power Of Socio-Knowledge Association For Enterprise Risk Identification In Stock Market, Zhenghao Liu, Keng Siau, Shaochen Yang, Feicheng Ma
Research Collection School Of Computing and Information Systems
Potential risk signals reflected in supply chain and equity connections between enterprises and social connections between investors are becoming crucial to identifying enterprise risks in addition to basic financial indicators. Traditional risk management systems face challenges in adapting to these complexities, highlighting the need for a proactive paradigm shift in risk management. Leveraging graph models such as social networks and knowledge graphs offers a promising approach to identifying and managing potential associated risks effectively. To bridge existing research gaps, a novel risk identification framework driven by social-knowledge graphs has been proposed, integrating graph deep learning and reinforcement learning techniques guided …
Ef21 With Bells & Whistles: Six Algorithmic Extensions Of Modern Error Feedback, Ilyas Fatkhullin, Igor Sokolov, Eduard Gorbunov, Zhize Li, Peter Richtarik
Ef21 With Bells & Whistles: Six Algorithmic Extensions Of Modern Error Feedback, Ilyas Fatkhullin, Igor Sokolov, Eduard Gorbunov, Zhize Li, Peter Richtarik
Research Collection School Of Computing and Information Systems
First proposed by Seide (2014) as a heuristic, error feedback (EF) is a very popular mechanism for enforcing convergence of distributed gradient-based optimization methods enhanced with communication compression strategies based on the application of contractive compression operators. However, existing theory of EF relies on very strong assumptions (e.g., bounded gradients), and provides pessimistic convergence rates (e.g., while the best known rate for EF in the smooth nonconvex regime, and when full gradients are compressed, is O(1/T2/3), the rate of gradient descent in the same regime is O(1/T)). Recently, Richtàrik et al. (2021) proposed a new error feedback mechanism, EF21, based …
Less Is More: On The Importance Of Data Quality For Unit Test Generation, Junwei Zhang, Xing Hu, Shan Gao, Xin Xia, David Lo, Shanping Li
Less Is More: On The Importance Of Data Quality For Unit Test Generation, Junwei Zhang, Xing Hu, Shan Gao, Xin Xia, David Lo, Shanping Li
Research Collection School Of Computing and Information Systems
Unit testing is crucial for software development and maintenance. Effective unit testing ensures and improves software quality, but writing unit tests is time-consuming and labor-intensive. Recent studies have proposed deep learning (DL) techniques or large language models (LLMs) to automate unit test generation. These models are usually trained or fine-tuned on large-scale datasets. Despite growing awareness of the importance of data quality, there has been limited research on the quality of datasets used for test generation. To bridge this gap, we systematically examine the impact of noise on the performance of learning-based test generation models. We first apply the open …
On-Demand Scenario Generation For Testing Automated Driving Systems, Songyang Yan, Xiaodong Zhang, Kunkun Hao, Haojie Xin, Yonggang Luo, Jucheng Yang, Ming Fan, Chao Yang, Jun Sun, Zijiang Yang
On-Demand Scenario Generation For Testing Automated Driving Systems, Songyang Yan, Xiaodong Zhang, Kunkun Hao, Haojie Xin, Yonggang Luo, Jucheng Yang, Ming Fan, Chao Yang, Jun Sun, Zijiang Yang
Research Collection School Of Computing and Information Systems
The safety and reliability of Automated Driving Systems (ADS) are paramount, necessitating rigorous testing methodologies to uncover potential failures before deployment. Traditional testing approaches often prioritize either natural scenario sampling or safety-critical scenario generation, resulting in overly simplistic or unrealistic hazardous tests. In practice, the demand for natural scenarios (e.g., when evaluating the ADS's reliability in real-world conditions), critical scenarios (e.g., when evaluating safety in critical situations), or somewhere in between (e.g., when testing the ADS in regions with less civilized drivers) varies depending on the testing objectives. To address this issue, we propose the On-demand Scenario Generation (OSG) Framework, …