Digital Commons Network^™

Atg Conjugation-Dependent/Independent Mechanisms Underlie Lysosomal Stress-Induced Tfeb Regulation, Shiori Akayama, Takayuki Shima, Tatsuya Kaminishi, Mengying Cui, Jlenia Monfregola, Kohei Nishino, Andrea Ballabio, Hidetaka Kosako, Tamotsu Yoshimori, Shuhei Nakamura

Duncan NRI Faculty and Staff Publications

TFEB, a master regulator of autophagy and lysosomal biogenesis, is activated by several cellular stresses including lysosomal damage, but its underlying mechanism is unclear. TFEB activation during lysosomal damage depends on the ATG conjugation system, which mediates lipidation of ATG8 proteins. Here, we newly identify ATG conjugation-independent TFEB regulation that precedes ATG conjugation-dependent regulation, designated Modes I and II, respectively. We reveal unique regulators of TFEB in each mode: APEX1 in Mode I and CCT7 and/or TRIP6 in Mode II. APEX1 interacts with TFEB independently of the ATG conjugation system, and is required for TFEB stability, while both CCT7 and …

Du Bois And The Promotion Of Admissions Diversity: A Post-Grutter Analysis, Austin Burke

Richmond Public Interest Law Review

Today’s outlook on higher education for people of color is in question. Because of the downfall of affirmative action, higher educational facilities must look to factors other than race to increase or maintain diversity. W.E.B. Du Bois viewed education as a means to uplift Black people. In a time of uncertain missions of higher education, and a steadfast commitment to a con- tinuous uplift of the Black community, it is paramount to view all angles of solutions to the end of affirmative action. In analy=zing the shifting educa- tional philosophy of Du Bois against the modern struggle of maintaining di- …

The Unspoken Limitations Of Educational Choice: Iowa's Students First The Unspoken Limitations Of Educational Choice: Iowa's Students First Act, Courtney Squires

Richmond Public Interest Law Review

“Education, then beyond all other devices of human origin, is the great equalizer of the conditions of men, the balance wheel of the social machin- eyt — Horace Mann, 1848 INTRODUCTION Horace Mann, the “father of the common school” saw education “as the bedrock of democracy™ and believed it should be “universal, nonsectarian, [and] free.” Its “aims should be social efficiency, civic virtue and character, rather than mere leaming or the advancement of sectarian ends.™ While ed- ucation may still be the bedrock of our democracy, it has become less uni- versal, more sectarian, and—depending on the school—costly. For over …

Climate Change: The World In Uncharted Waters – Exploring The Nexus Of Human-Rights Based Legal Instruments And Climate Change, Emma V. Wilson

Richmond Public Interest Law Review

The framework of human rights is based on a “fundamental and irrevoca- ble belief in the dignity and worth of every individual.”! While many differ- ent channels have emerged for protecting human rights in the face of global climate change, there is still significant room for improvement. For decades, there was no formal recognition of human-centered environmental rights.? The recent United Nations General Assembly (“UNGA”) acknowledgement of a right to a clean, healthy, and sustainable environment is a tool that can “facilitate the reconceptualization of human rights law to better adapt to the negative impacts of climate change.” It represents …

Criminalizing Moral Failures: An Exploration Of The Difference Between Wrongfully Convicted Men And Women, Caroline Brady

Richmond Public Interest Law Review

In the United States, more than 1.9 million people are confined across local jails, state prisons, and federal prisons and jails.! Some of those people are innocent of the crimes for which they were convicted. In 2022 alone, 233 people were exonerated of crimes they did not commit.? Collectively, these 233 exonerees lost 2,245 years of their lives to incarceration.? Over the last few decades, as criminal justice reform movements have gained momentum, more attention has tumed to wrongful convictions. Yet much of the consideration has been dedicated to men, not women.* What ex- plains the lack of women featured …

Strategies To Improve Access To Clinical Informatics Specialist Consultations In An Acute Care Hospital System, Holli Miller

Walden Dissertations and Doctoral Studies

Access to clinical informatics specialist (CIS) consultations is essential for optimizing electronic health record (EHR) use in acute care hospital systems. Limited availability of CIS support contributes to clinician burnout, workflow inefficiencies, and patient safety risks. The purpose of this integrative review was to identify strategies to improve access to CIS consultations in acute care settings. A comprehensive literature search across multiple databases yielded 656 articles, with 24 meeting inclusion criteria based on relevance and methodological rigor, evaluated using the Johns Hopkins Nursing Evidence-Based Practice appraisal tools. These studies, published between 2019 and 2024, underwent thematic analysis guided by the …

Ohio University Faculty Senate Minutes October 6, 2025, Angela Brock

Faculty Senate Minutes

No abstract provided.

Jaclynn Tracy And Donna Schmitt-Oliver, Oral History Interview, 2025, Matt Jones

Oral Histories

The EMU Women in Philanthropy Oral History Project documents the organization's history across its 15 years of giving to the EMU community. In 2025, Matt Jones talked to Jaclynn Tracy--EMU alum, College of Education emerita, and former Leadership and Counseling Department Head--and Donna Schmitt-Oliver--Leadership and Counseling emerita, and former Associate Dean of the College of Education--about their roles in WIP. Tracy and Schmitt-Oliver were two of the foundational members of WIP and served as the organization's inaugural co-chairs in 2010. In this interview both women reflect on the place of philanthropy in their upbringings, the impetus for creating WIP, as …

Exploring The Correlation Between Pupil Distance And Myopia Prevalence: An Observational Bioanthropology Study In Surabaya, Anggitha Hayuning Kinasih, Dwi Martha Nur Aditya, Y Adhimas Setyo Wicaksono

Folia Medica Indonesiana

Bioanthropology integrates biological and cultural perspectives, thereby enhancing our understanding of human health across populations. Myopia is a significant refractive error affecting potentially 2.5 billion people globally by the end of the decade. Bioanthropological theories suggest that pupil diameter and distance contribute to axial elongation and the progression of myopia. Nevertheless, current literature lacks empirical validation through rigorous hypothesis testing, highlighting a gap in comprehension. The research explores the relationship between pupil distance and the incidence of myopia via empirical assessments in Surabaya. An observational cross-sectional study was conducted, which involved pupil distance measurements and eye refraction assessments. Inclusion criteria …

Lenox Twins Llc V. Watson

All Decisions

In this rent-stabilized nuisance holdover proceeding, the tenant moved for summary judgment to dismiss the petition, while the landlord cross-moved to amend the petition. The court found the landlord's predicate notice sufficiently detailed the alleged nuisance conduct. However, the tenant presented a sworn affirmation flatly denying the nuisance allegations, including throwing garbage from windows. The landlord failed to offer any rebuttal from an individual with personal knowledge or competent corroborating evidence. Consequently, the court granted the tenant's motion for summary judgment, dismissing the petition, and denied the landlord's cross-motion as moot.

Westminster Apts. Llc V. Deetjen

All Decisions

In this nuisance/breach of lease holdover proceeding, the tenant moved to dismiss, arguing the landlord's petition was defective for failure to serve a 30-day termination notice under the federal CARES Act, as the property had a federally backed mortgage. The court denied the motion, holding that the CARES Act's 30-day notice requirement applies exclusively to non-payment proceedings, not to holdover proceedings based on nuisance or lease breach. The court found that subsections (b) and (c) of 15 U.S.C. § 9058 must be read in unison, and the notice provision (c) is implicitly limited by subsection (b)'s express reference to non-payment …

Perceptions Of Whole Plant-Based Diets And Weight Among Hispanics In Miami, Florida, Zoraida Powell

Walden Dissertations and Doctoral Studies

Being overweight or obese poses major public health concerns and contributes to the development of chronic illnesses. While researchers have explored how a total plant-based diet impacts excess body weight or obesity, there is still a lack of clarity about how Hispanics living in Miami, FL, perceive or understand this diet concerning overweight and obesity. Using a generic qualitative approach, this study was conducted on how Hispanics in Miami, FL, understand and view a whole plant-based diet (WPBD) for preventing and reducing overweight and obesity. Through interviews with 14 diverse Hispanic participants, the study revealed that they see WPBD as …

The Free Press Vol. 57, Issue 4, 10-06-2025, Julz Levesque, Caraline Squires

Free Press, The

Shutdown Stalemate--College Dreams at Risk--The Portland Farmer's Market Is in Full Bloom--First Pingo of the School Year--Common Ground Country Fair--USM Honors POW-MIA Recognition Day with Flag Raising Ceremony

14th Street Associates L.P. V. Przystup

All Decisions

In this holdover proceeding alleging the tenant's objectionable conduct due to noxious odors, the tenant filed a multi-part motion. The court denied the tenant's motion to dismiss, finding the landlord's predicate notices sufficiently particular regarding the nature and dates of the alleged odors. However, the court largely granted the tenant's motion to compel a bill of particulars, holding that identifying information of complaining tenants constituted amplification of the landlord's claims. Information about the landlord's agents, however, was deemed evidentiary and beyond the scope. The court denied the tenant's motion for discovery, finding no ample need, and the case was scheduled …

Mcsa Forum Minutes 10/06/2025, Morris Campus Student Association

Morris Campus Student Association

No abstract provided.

Fema Public Policy Impacts On Emergency Preparedness In Florida, Sara Sambolin

Walden Dissertations and Doctoral Studies

Older adults are at an increased risk of mortality during hazardous emergencies; therefore, it is crucial to comprehend how current emergency preparedness policies are related to preparedness perceptions of older adults. Findings in recent literature identified the underrepresentation of older adults in Emergency Preparedness studies across all areas and Counties of the state of Florida as a gap that needs to be addressed. The purpose of this quantitative correlational study was to examine the relationship between the 2023 FEMA policy on emergency preparedness and the self-reported degree of preparedness among Florida’s older adult residents in urban and rural areas across …

Static Malware Analysis For Incident Response: Developing A Tactical Aid With Ember, Joel Meoak, Shengjie Xu

Journal of Cybersecurity Education, Research and Practice

Incident responders face a variety of challenges when identifying malware using existing solutions, particularly when rapid tactical decisions are needed. Traditional malware detection methods are often signature-based, limiting their effectiveness to previously known threats detected by anti-virus (AV) engines. Online analysis tools introduce confidentiality risks, potentially alerting adversaries that their actions are under scrutiny. While free sandbox environments offer useful capabilities, they often require substantial setup time and hardware resources that may not be available in the field. This research leverages the Elastic Malware Benchmark for Empowering Researchers (EMBER) dataset to develop a lightweight, portable tactical decision aid that enables …

Atg16l1 Controls Mammalian Vacuolar Proton Atpase, Thabata L A Duque, Masroor Paddar, Einar Trosdal, Ruheena Javed, Lee Allers, Michal H Mudd, Prithvi Akepati, Soumya R Mishra, Michelle Salemi, Brett Phinney, Shawn B Bratton, Thomas Wileman, Vojo Deretic

Faculty, Staff and Student Publications

The mechanisms governing mammalian proton pump V-ATPase function are of fundamental and medical interest. The assembly and disassembly of cytoplasmic V1 domain with the membrane-embedded V0 domain of V-ATPase is a key aspect of V-ATPase localization and function. Here, we show that the mammalian protein ATG16L1, primarily appreciated for its role in canonical autophagy and in noncanonical membrane atg8ylation processes, controls V-ATPase. ATG16L1 knockout elevated V-ATPase activity, increased V1 presence on endomembranes, and increased the number of acidified intracellular compartments. ATG16L1's ability to efficiently bind V-ATPase was required for its inhibitory role in endolysosomal acidification and for control of Mycobacterium …

Ndls Communicator: Week Of 10.06.25, Notre Dame Law School

NDLS Communicator

The Latest News

• Faculty profile: Professor Mary Ellen O'Connell, globally influential scholar of international law and peace
• Panel explores Catholic Social Teaching and human rights in Africa

Faculty Briefs

• Nicole Garnett
• Sadie Blanchard
• Patrick Corrigan
• Roger Alford
• Mary Ellen O'Connell
• Christine Venter
• Paolo Carozza
• Avishalom Tor
• Emily Bremer
• Fr. John Paul Kimes
• Derek Muller
• Judy Fox
• Gerard Bradley

ND Law in the News

• Notre Dame Law School's partnership with Harvey AI was featured in a Law360 article.

Student News

• Third-year law student Dennis Weiboldt III wrote an article for First Things Magazine about the Red Mass

Events

• Law and Economics …

The Taxonomy And Origins Of Folia: A Brief Review, Donald G. Davis, Louise D. Hose, Harvey R. Duchene

International Journal of Speleology

All folia demonstrate a few common elements: folia (singular, folium) are planar or sub-planar speleothems, slanting downward and away from cave walls and ceilings, and genetically associated with fluctuating environmental interfaces. They were first identified and named from examples in western USA hypogenic caves but have since been identified elsewhere in the world. Folia shelves are typically composed of calcite and interweave smoothly along sub-horizontal contours. Calcite accretion, both chemical and mechanical from suspended particles, follows water-surface fluctuations to form protrusions in arrays along walls and ceilings where new accretion tends to follow the water-surface downward during descending phases, gradually …

The Factorial Construction Of The Psychological Capital Scale And Its Relationship To Some Variables Among Faculty Members At Al-Baha University, Bandar Hamdan Ahmed Alzahrani

University of Bisha Journal for Educational Sciences

The study aimed to reveal the factors contributing to the construction of the psychological capital variable among faculty members at Al-Baha University. And to identify the differences between the average scores of the study sample on the psychological capital scale, which are attributed to the impact of the variable of sex, the nature of the college, nationality, and academic rank. The study used the psychological capital scale prepared by the researcher, and the results of the study showed the presence of four main factors constituting psychological capital: hope, self-efficacy, flexibility, optimism, and the absence of a statistically significant difference between …

Engagement By Design: Belongingness, Cultural Value Orientations, And Pathways Into Emerging Technologies, Daisuke Akiba, Michael Perrone, Caterina Almendral, Rebecca Garte

Publications and Research

This theoretical article examines how belongingness, defined as the sense that one’s participation is legitimate and valued, interacts with cultural value orientations to help explain persistent disparities in U.S. technology engagement, including emerging technologies, across racial and ethnic groups. While structural barriers (e.g., racism, poverty, linguistic bias, etc.) remain essential to understanding such inequity, we argue that engagement patterns in technology also reflect how different cultural communities may define and experience belongingness in relation to digital domains. Drawing on Triandis and Gelfand’s framework, and focusing specifically on educational contexts, we propose the Belongingness through Cultural Value Alignment (BCVA) model, whereby …

Raising Riyadh’S Readiness To Host Expo 2030 And World Cup 2034 Visitors, Mohammed Ahmed Jabri, Mohammad Alghamdi

Emirates Journal for Engineering Research

Riyadh is the focus of attention of many local and expatriate tourists, and is witnessing a qualitative shift and rapid development in preparation for hosting Expo Riyadh 2030 and the FIFA World Cup 2034. This research sheds light on an important topic, which is the need to provide sufficient inventory in the hospitality sector to meet the expected needs for these two years. The research followed the methodology of studying and analysing data and statistics collected from the annual reports of the Ministry of Tourism and the General Authority for Statistics (Second data resource); to try to predict the reality …

Promising The First Amendment: (De)Regulating Speech In Higher Education, Max M. Schanzenbach, Kimberly A. Yuracko

Northwestern University Law Review

The war between Hamas and Israel has caused havoc in higher education. Amid student unrest, alumni pressure, congressional hearings, civil rights investigations, and student lawsuits, universities stand at a crossroads. The current situation, in which most private universities unevenly regulate student speech under ambiguous student codes, is not sustainable politically or legally. A tsunami of litigation and regulatory actions has already begun. One increasingly favored response is for private universities to more vigorously enforce existing codes or expand their scope. An alternative is for private universities to deregulate student expression and commit by contract to the First Amendment. This Article …

Moving Beyond Traditional Legal Scholarship Impact Rankings, John Cannan

Faculty Publications

Legal academia is likely stuck with law faculty scholarly impact rankings—that is, using citation counts to judge a law faculty’s reputation and influence. But why can’t we produce better, more useful studies? Current rankings rely on outdated methods. Moreover, these rankings—touted by their creators as objective—suffer from long-standing flaws. They are also grounded in limited understandings of legal citations as sources of information. This paper calls on law librarians to advance legal citation research by adopting methodologies from other information sciences and developing legal citation taxonomies and theories.

Take In Case Of Emergency: Reconciling Necessity Takings With The Original Meaning Of The Takings Clause, Tony Smith

Northwestern University Law Review

Does the Fifth Amendment’s Takings Clause permit the state to destroy property without compensation whenever it declares an emergency? The long-standing doctrine of necessity empowers the state to do exactly that.

Courts dating back to common law England have permitted governments to claim a privilege of necessity to avoid paying for private property they destroy in times of crisis. The privilege rests on the principle that the public good sometimes outweighs the harm the individual suffers. Today’s courts and academics stretch this principle to its limits, arguing necessity should be used as a vehicle for combating all manner of social …

What On Earth Is A Burden On Interstate Commerce?, Andrew Jordan

Northwestern University Law Review

What is a burden on interstate commerce? That’s an important question under the Dormant Commerce Clause’s Pike balancing test. But it’s a question whose answer has proven elusive. This shouldn’t be a surprise. After all, states disagree about what counts as a burden or a benefit, and how much weight each has. And there aren’t any obvious constitutional principles we can point to for resolving those disagreements. Recently, some scholars have tried to ground dormant commerce doctrine in economic cost–benefit analysis. The supposed virtue of that approach is that it is neutral as to competing preferences. Thus, for the Court …

Judge Joel Flaum And Judicial Virtue, Amy J. St. Eve, Michael Y. Scudder

Northwestern University Law Review

No abstract provided.

Generative Suspicion And The Risks Of Ai-Assisted Police Reports, Andrew Guthrie Ferguson

Northwestern University Law Review

Police reports play a central role in the criminal justice system. Many times, police reports exist as the only official memorialization of what happened during an incident, shaping probable cause determinations, pretrial detention decisions, motions to suppress, plea bargains, and trial strategy. For over a century, human police officers wrote the factual narratives that shaped the trajectory of individual cases and organized the entire legal system.

This practice is about to change with the creation of AI-assisted police reports. Today, with the click of a button, large language models (LLMs), a type of generative AI using predictive text capabilities, can …

Dream A Little Dream Of Licensing: Jazz And The § 115 Compulsory Music Reproduction License, Jackson S. Roberg

Northwestern University Law Review

The compulsory music reproduction license codified at 17 U.S.C. § 115 allows anyone to obtain the right to record another version of, or “cover,” a previously published musical work. Invoking the compulsory license, however, comes at a dramatic cost. Under § 115(a)(2), the licensee cannot copyright any original musical material they compose for the cover without express permission from the underlying copyright owner, even if that material would otherwise be copyrightable. This limitation gravely harms jazz music, as jazz relies on dynamic recompositions of preexisting music. Jazz musicians depend on compulsory licenses to record the reinterpretative covers essential to the …