Digital Commons Network^™

Deep Learning For The Early Detection Of Invasive Ductal Carcinoma In Histopathological Images: Convolutional Neural Network Approach With Transfer Learning, Naga Shreya Chilumukuru, Pragya Priyadarshini, Yawo Ezunkpe

Faculty Research, Scholarly, and Creative Activity

Background: Invasive ductal carcinoma (IDC) is considered the most common form of breast cancer, accounting for a significant percentage of mortality worldwide. Therefore, its early detection is vital to further improve patients’ outcomes and survival rates. However, conventional diagnostic methods in the form of manual histopathological examinations are time-consuming, subjective, and prone to errors. Therefore, there is an urgent need to develop automated solutions for accurate IDC detection in histopathology images to assist pathologists in clinical decision-making. Objective: We aim to develop and validate a convolutional neural network (CNN) model for early detection of IDC by analyzing histopathological images. The …

Native Ticks As A Model For The Effectiveness Of Fire As A Tool For The Management Of Cattle Fever Ticks In South Texas, Lauren P. Maestas, Sarah E. Mays Maestas, Kathleen M. Yeater, Manuel Zavala, Reyes Garcia, John A. Goolsby

School of Integrative Biological & Chemical Sciences Faculty Publications

The species of cattle fever ticks (CFT) present in North America, Rhipicephalus (=Boophilus) annulatus, and R. microplus, remain an important agricultural and economic burden. The use of acaricides to control CFT has been a common practice over the past half century. However, alternative strategies for control are needed to improve the options for sustainable pest control. Fire is a tool to manage vegetation, and some evidence supports its potential for use to control ticks. We evaluated the effectiveness of fire as a management tool for ticks in South Texas. Our site was a 28.2-ha property in Cameron …

Fitisemanu V. United States: An Analysis Of The Impact Of The Supreme Court’S Denial Of Certiorari And The Future Citizenship (Or Lack Thereof) For American Samoans, Moore, Michelle

Santa Clara Law Review

Does the Citizenship Clause of the Fourteenth Amendment confer United States citizenship on individuals born in American Samoa? How does one reconcile the competing values of preserving a unique culture and receiving the full protections of the U.S. Constitution? These were the issues brought before the court in Fitisemanu v. U.S.

American Samoa is the only U.S. territory where individuals born there are born as U.S. nationals, rather than U.S. citizens. While being born a U.S. national has certain rights and privileges not provided to noncitizens and nonnationals, the idea of distinguishing between a U.S. citizen and a U.S. national …

Prefrontal Cortex Astrocytes Modulate Distinct Neuronal Populations To Control Anxiety-Like Behavior, Eunyoung Kim, Hairuo Du, Yanqi Tan, Brandon L Brown, Yaowen Chang, Blanca Díaz-Castro, Jonathan V Sweedler, Xinzhu Yu

Faculty, Staff and Student Publications

Accumulating evidence has supported diverse regulatory functions of astrocytes in different neural circuits as well as various aspects of complex behaviors. However, little is known about how astrocytes regulate different neuronal subpopulations that are linked to specific behavioral aspects within a single brain region. Here, we show that astrocytes in the medial prefrontal cortex (mPFC) encode anxiogenic environmental cues in freely behaving mice. Silencing mPFC astrocyte Ca

Tracing Priming Effects In Palsa Peat Carbon Dynamics Using A Stable Isotope-Assisted Metabolomics Approach, Christian Ayala-Ortiz, Moira Hough, Elizabeth K. Eder, David W. Hoyt, Rosalie K. Chu, Jason Toyoda, Steven J. Blazewicz, Patrick M. Crill, Ruth Varner, Scott R. Saleska, Virginia I. Rich, Malak M. Tfaily

Michigan Tech Publications

Introduction: Peatlands store up to a third of global soil carbon, and in high latitudes their litter inputs are increasing and changing in composition under climate change. Although litter significantly influences peatland carbon and nutrient dynamics by changing the overall lability of peatland organic matter, the physicochemical mechanisms of this impact—and thus its full scope—remain poorly understood. Methods: We applied multimodal metabolomics (UPLC-HRMS, ¹H NMR) paired with ¹³C Stable Isotope-Assisted Metabolomics (SIAM) to track litter carbon and its potential priming effects on both existing soil organic matter and carbon gas emissions. Through this approach, we achieved molecule-specific tracking …

Phytochemical Analysis And Appraisal Of Antiproliferative Activity Of Magnolia Alejandrae, José E. Caballero-Chávez, Alma D. Paz-Gonzalez, Diana V. Navarrete-Carriola, Fabian E. Olazarán, María Miriam Estevez-Carmona, Benjamin Nogueda-Torres, Fernando Emiliano Jiménez-Mondragón, Melany X. Márquez-Aguilar, Carmen Michelle Pineda-Alcala, Debasish Bandyopadhyay

School of Integrative Biological & Chemical Sciences Faculty Publications

Background: Magnolia alejandrae is a tree endemic to Tamaulipas, Mexico, distributed in the forests of the Sierra Madre Oriental. Objective: Our objective was to analyze the secondary metabolite profile of different parts of M. alejandrae and evaluate their antiproliferative activity in vitro. Methods: Different extracts of leaf, bark, and fruit were obtained using conventional and unconventional extraction methods with solvents of different polarity. The extracts were analyzed by Ultra-Performance Liquid Chromatography-Mass Spectra (UPLC-MS), and their antiproliferative activity against cancer cell lines was determined. Results: The primary yields of the extracts obtained from M. alejandrae ranged from 8.32% to 36.19%. Three …

Implementation Of Culturally Relevant Pedagogy In Elementary Reading Instruction, Chelsea Renae Little

Walden Dissertations and Doctoral Studies

Culturally relevant pedagogy (CRP) has been shown to help educators address the unique educational needs of African American students. While research has supported the belief that CRP promotes a sense of belonging and positively influences academic achievement, there remains a lack of research regarding elementary teachers’ perceptions of their implementation of CRP specifically when teaching reading to African American students. Framed by Ladson-Billings’s CRP framework, the purpose of this basic qualitative study was to explore elementary teachers' perceptions of their implementation of CRP when teaching reading to African American students. Using a basic qualitative design, data were collected through semistructured …

Β-Catenin Functions As A Molecular Adapter For Disordered Cbaf Interactions, Yuen San Chan, Qinyu Gao, Sarah A Robinson, Wenzhi Wang, Ruzena Filandrova, Lisa-Maria Weinhold, Mario Loeza Cabrera, Miao Zhang, Chandra Shekar R Ambati, Antonio M Lerario, Nagireddy Putluri, Katja Kiseljak-Vassiliades, Margaret E Wierman, Mouhammed Amir Habra, Gary D Hammer, Vaclav Veverka, Katerina Cermakova, H Courtney Hodges

Faculty, Staff and Students Publications

BAF (SWI/SNF) chromatin remodelers engage binding partners to generate site-specific DNA accessibility. However, the basis for interaction between BAF and divergent binding partners has remained unclear. Here, we tested the hypothesis that scaffold proteins augment BAF's binding repertoire by examining β-catenin (CTNNB1) and steroidogenic factor 1 (SF-1, NR5A1), a transcription factor central to steroid production in human cells. BAF inhibition rapidly opposed SF-1/β-catenin enhancer occupancy, impairing SF-1 target activation and SF-1/β-catenin autoregulation. These effects arise due to β-catenin's role as a molecular adapter between SF-1 and an intrinsically disordered region (IDR) of the canonical BAF (cBAF) subunit ARID1A. In contrast …

Dclk1 Isoform (Dclk1-S) As A Critical Player In Promoting Inflammation, Tissue Remodeling, And Emt In Mouse Models Of Colitis., Kafayat Yusuf, Badal C. Roy, William L. Hauser, Mazin Al-Kasspooles, Sierra Sanchez, Thomas M. Attard, Dong Pei, Venkatesh Sampath, Shrikant Anant, Shahid Umar

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND AND AIMS: The Doublecortin-like kinase-1 (DCLK1) plays a chemosensory role in the gut. It's role in the context of inflammatory diseases including inflammatory bowel disease (IBD), has not been thoroughly investigated. This study explored the role of the DCLK1 isoform (DCLK1-S) in promoting infectious/chemical colitis by utilizing high-throughput imaging mass cytometry (IMC).

METHODS: Transgenic mice were either infected with Citrobacter rodentium (CR) or received DSS and tissues/cells were processed via standard techniques. IMC workflow was adapted by Fluidigm (renamed Standard BioTools). Raw data was fed to Multiplexed Cell Dataset (MCD) Viewer for image generation and analyzed via histoCAT. Promoters …

Dragon Guitars And Sexy Zombies: Tracing The Meta-Motion Of The Naga Motif In Northeast Thailand, Aaron Michael Stanley

Dartmouth College Master’s Theses

Abstract

This thesis traces the evolving symbolism of the Naga motif (a mythic water serpent) in Northeast Thailand through a framework I call meta-motion, which maps symbolic persistence of this cultural signifier and boundary marker across four cultural horizons—animist (Z), Hindu–Khmer (B), Buddhist (A), and modern/global (C). Like electrons in quantum super position, symbolic motifs circulate as overlapping “waves” of potential meaning and are concretized into cultural “particles” only when recruited for specific ritual, commercial, or political purposes. I add a bookend extension to Chang’s Hindu-Buddhist (B/A) typology with the addition of Horizons Z and C in order to make …

Tort Liability For Failure To Age Gate: A Promising Regulatory Response To Digital Public Health Hazards, Matthew B. Lawrence, Brett Frischmann, Avi Sholkoff

Faculty Publications

Tort liability for failure to “age gate” is a promising legal response to the public health hazards of AI, social media, sports gambling, and other digital spaces. Tort liability for failure to “age gate” hinges liability for harms to minors on an app’s failure to take reasonable steps to prevent minors from gaining access or otherwise to apply appropriate governance rules, such as privacy-protective default settings or ensuring genuine parental consent. While no one legal response is a panacea, tort liability for failure to age gate carries several distinctive advantages that make it a particularly promising option at this stage …

2025-08-21 Faculty Senate Meeting Minutes (Last Meeting Of The Lennex Administration), Morehead State University. Faculty Senate.

Faculty Senate Records

Faculty Senate meeting minutes from August 21, 2025. The last meeting of Dr. Lennex's administration.

2025-08-21 Faculty Senate Newsletter, Morehead State University. Faculty Senate.

Faculty Senate Records

Faculty Senate newsletter from August 21, 2025.

Scorpions Of The Horn Of Africa (Arachnida: Scorpiones). Part Xliii. Lanzatus Fuscipalpis Sp. N. From Ethiopia (Buthidae), František Kovařík, Graeme Lowe

Euscorpius

The rare Horn of Africa buthid genus Lanzatus Kovařík, 2001, known only from Somalia and Somaliland, is recorded for the first time from Ethiopia. We describe a new species Lanzatus fuscipalpis sp. n. fully illustrated with color photographs showing its morphology, habitus, hemispermatophore, and collection sites.

Textbooks: Required, Alternatives, Hybrid, Or Disappearance, William Saunders, Carlton Perkins, Michara Delaney-Fields

Southwestern Business Administration Journal

The conversations around transformational changes in higher education are centered around a myriad of issues. Technology, the lasting effects of the pandemic, student satisfaction and readiness for future employment requirements are a few of the leading concerns. However, one subject that is not receiving enough attention is the growing resistance and hesitation among college students to purchase textbooks. Although the movement has not reached the status of a full-blown protest or outright refusal, there is enough attention being brought to the subject that educators may want to be prepared for an eventual change. The need and requirement for textbooks in …

System And Method For Thermochromic Indicator Payment Card, Mohit Koul, Rohit Mukherjee

Defensive Publications Series

The present disclosure related to a system and method for thermochromic indicator payment card. The system and method more specifically implements thermochromic technique. The payment card is embedded with thermochromic material that can change colour in response to temperature fluctuation, providing a passive and dynamic visual indicator for transaction verification and security alerts. Further, the present disclosure enables real time transaction awareness and fraud detection without relying on electronic alerts and external power sources.

The Innovative Technique For Obtaining The Solutions Of Jeffery Hamel Nano-Fluids Flow Problem, Haedir Abd Alrazak Namoos, Abeer Majeed Jasim

Iraqi Journal for Computer Science and Mathematics

The study of heat transfer in nanofluid flows is increasingly important in many engineering, medical, and industrial applications. These fluids offer enhanced thermal cooling properties compared to conventional fluids. The research problem lies in the challenges of solving the Jeffrey-Hammel flow model for nanofluids, which includes coupled nonlinear differential equations that describe the thermal and hydrodynamic behavior of this type of flow, taking into account the influence of multiple factors such as the type, size, and concentration of nanoparticles. This research aims to propose a new hybrid analytical technique that combines the Laplace transform and the q-homotopy analysis technique with …

Underlying Causes Linking Foster Care And The Criminal Justice System, Marcia D. Wheeler

Master of Arts in Human Services

This research expands on the ongoing statewide crisis within the foster care system that needs to be properly addressed to benefit future and current foster youth. Research has found a connection between foster care and prison, often referred as the “foster-care-to-prison-pipeline.” This study aimed to explore the impact of trauma experienced by current and former foster youth through a life course lens looking at crucial areas of development using a mixed methodology supported by theoretical theories that explored the connection between foster care and the criminal justice system. The results showed that current and former foster youth face many adversities …

Not In My Neighborhood! The Harsh Realities Of Sex Offender Registration Laws, Kyle B. Rossow

Master of Arts in Human Services

Sex offender registration laws were created in response to public fear and high-profile tragedies, with the primary goal of enhancing public safety through stringent monitoring of sexual offenders. This paper explores the historical development of these laws, including high-profile cases that later influenced legislative acts, such as the tragic incidents of Jacob Wetterling, Megan Kanka, and Adam Walsh. This paper also explores how media portrayals and public opinion factor into these legislative decisions. While the laws aim to protect the public, they often result in collateral consequences for individuals who have to register. Sex offenders are often held back by …

Usa V. Carl Rose

2025 Decisions

USDC for the Eastern District of Pennsylvania

Usa V. David Somerville

2025 Decisions

USDC for the Western District of Pennsylvania

Precarious Privilege: Exploring The Intersection Of White Teacher Habitus And Social Justice In International Schools, Kevin L. Workman

Dissertations

This qualitative study explored the underresearched phenomenon of White teacher allyship within an emergent diversity, equity, inclusion, and justice (DEIJ) movement in international schools. Gaining momentum in 2020 as a digital, postcolonial counterstory, the movement exposed structural inequities and racism across the international school ecosystem. Applying an antiracist reading of Bourdieu’s (1977) theory of practice, the study analyzes how White teachers (n = 8) from diverse international contexts understand, experience, and assess their participation in DEIJ activities. Thematic analysis of interview data corroborated the digital voices, explicitly identifying White supremacy as a key force shaping the field’s doxa. The study …

Boilermaker Blacksmith National Pension Trust V. Maiden Holdings Ltd

2025 Decisions

USDC for the District of New Jersey

Andrew Fields V. Bop

2025 Decisions

USDC for the Middle District of Pennsylvania

Commonwealth Times 2025-08-20

Commonwealth Times, 1969-

No abstract provided.

Ethics Committees In Outpatient Medical Practice: A Scoping Review, Milan Arya, Tyler Cholankeril, Marlowe Bogino, Meghan Crnic, Niharika Sathe, Isha M. Di Bartolo

Cooper Rowan Medical Journal

Introduction: This scoping review consolidates existing research on outpatient ethics committees (OECs). While inpatient or hospital ethics committees are well-researched and established, OECs are scarce in number and have received less attention from scholars, ethicists, and physicians, despite the increase in outpatient care utilization over the past two decades.

Methods: We conducted a scoping review following the JBI Manual for Evidence Synthesis. Key information sources included MEDLINE PubMed, Embase, and Academic Search Complete. Gray literature searching was conducted through Web of Science Database, keyword searching in Google Scholar, and backward citation searching was utilized. Relevant articles were screened …

August 20, 2025, Faculty, Illinois Wesleyan University

2025-2026

No abstract provided.

Towards All-Under-Heaven: China’S Geoeconomic Strategy In The Asia-Pacific Region, Alfariza Dika Azzani

Global: Jurnal Politik Internasional

This research aims to understand China’s geoeconomic strategy in reshaping the alternative international order in the Asia-Pacific region. China’s economic rise increased its geopolitical influence and significance as a global great power. The Chinese Communist Party (CCP) government, under Xi Jinping, has adopted classical ideas in its foreign policymaking, including tianxia. Tianxia is a classical concept of a hierarchical Sinocentric international order. An empirical study was conducted on several cases of China’s economic policy and analysed with the congruence method to determine the correlation between the tianxia concept and China’s economic policy. Tianxia served as a paradigm and justification for …

Special Status Of African Regional States In The International Seabed Authority, Felicia Ratnasari Soedjianto, Marten Hanura, Muhammad Arief Zuliyan

Global: Jurnal Politik Internasional

Through the mandate of UNCLOS 1982 and the 1994 Agreement, the International Seabed Authority (ISA) exists as a regulatory regime for activities in the international seabed area. Interestingly, African countries are privileged over other countries by occupying the most seats on the ISA Council. In addition, the ISA's commitment to supporting the blue economy through the Africa Deep Seabed Resources project also accentuates the privileges of African countries. African countries' technological, financial, and knowledge capacity is minimal in seabed mining. Apart from this problem, this research aims to analyse the fundamental reasons for the ISA's actions that give privileges to …

Acoustic Characterization And Modeling Of Heated Supersonic Tactical Jet Aircraft And Launched Rockets, Logan Troy Mathews

Theses and Dissertations

Understanding and accurately modeling the acoustic sources and propagation of high-intensity tactical jet aircraft and rocket noise is essential for vehicle design, environmental impact assessment, and mitigation strategies. Despite progress in the understanding of these sources, significant challenges persist in both predictive modeling and noise mitigation. This dissertation advances both the characterization of full-scale supersonic tactical jet aircraft noise sources and the development of modern empirical prediction models for rocket launch noise. Across multiple measurement campaigns and modeling efforts, the work integrates advanced array signal processing, high-fidelity field measurements, and improved empirical methods to expand the physical understanding of source …