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A Causal-Comparative Study Of Full-Time Student Retention Rates Among Public Land-Grant Universities Based On Carnegie Engagement Classification Status And Availability Of Mental Health Counseling Services, Natriez B. Peterson Dec 2025

A Causal-Comparative Study Of Full-Time Student Retention Rates Among Public Land-Grant Universities Based On Carnegie Engagement Classification Status And Availability Of Mental Health Counseling Services, Natriez B. Peterson

All Dissertations

According to the National Center for Education Statistics (NCES) data, in 2019–2020, public four-year institutions had a retention rate of 81.5%, compared to 68.8% at private, for-profit institutions. Public universities use such metrics to address concerns about institutional effectiveness and educational value (Kelchen, 2018; Stryker, 1999; Tinto, 2017). This causal-comparative quantitative study examined whether full-time student retention rates differed significantly between Carnegie Community Engagement Classified Institutions and non-classified public land-grant universities, while controlling for the availability of institutional social support services. A two-way ANOVA tested the effects of Carnegie Engagement Classification Status and the presence of institutional social support services …


Tubulin Regulates Stability And Localization Of Stmn2 By Binding Preferentially To Its Soluble Form, Xiang Deng, Gary A Bradshaw, Marian Kalocsay, Timothy Mitchison Dec 2025

Tubulin Regulates Stability And Localization Of Stmn2 By Binding Preferentially To Its Soluble Form, Xiang Deng, Gary A Bradshaw, Marian Kalocsay, Timothy Mitchison

Faculty, Staff and Student Publications

The small, tubulin-binding protein STMN2 is highly expressed in neurons and is implicated in amyotrophic lateral sclerosis. STMN2 degrades rapidly and accumulates at axotomy sites, suggesting fast turnover is crucial for its neuroprotective function. We show that STMN2 was primarily degraded by the ubiquitin-proteasome system. Its membrane-targeting N-terminal domain promoted fast turnover, whereas its tubulin-binding domain promoted stabilization. Proximity labeling and imaging showed that tubulin binding reduced STMN2 targeting to trans-Golgi network membranes. Pull-down assays showed that tubulin binds preferentially to soluble over membrane-bound STMN2. Our observations suggest that STMN2 interconverts between a soluble, tubulin-bound form and a membrane-bound, tubulin-free …


Forecasting Chemoradiation Response Midtreatment For High-Grade Gliomas Through Patient-Specific Biology-Based Modeling, David A Hormuth, Maguy Farhat, Bikash Panthi, Holly Langshaw, Mihir D Shanker, Wasif Talpur, Sara Thrower, Jodi Goldman, Sophia Ty, Calliope Custer, Jeanne Kowalski, Thomas E Yankeelov, Caroline Chung Dec 2025

Forecasting Chemoradiation Response Midtreatment For High-Grade Gliomas Through Patient-Specific Biology-Based Modeling, David A Hormuth, Maguy Farhat, Bikash Panthi, Holly Langshaw, Mihir D Shanker, Wasif Talpur, Sara Thrower, Jodi Goldman, Sophia Ty, Calliope Custer, Jeanne Kowalski, Thomas E Yankeelov, Caroline Chung

Faculty, Staff and Student Publications

Purpose: The entire course of radiation therapy (RT) for high-grade glioma (HGG) is currently derived from pre-RT magnetic resonance imaging (MRI). Although it is possible to adapt RT during the course of treatment, it is often guided only by anatomical changes to the tumor. This study seeks to determine if a biology-based mathematical model, parameterized by patient-specific, multiparametric MRI (mpMRI) data, can accurately forecast HGG response during RT.

Methods and materials: Twenty one patients with HGG planned for 6 weeks of concurrent RT and chemotherapy were imaged weekly with mpMRI during RT and at 1, 2, and 3 months post-RT. …


Symbolic Justice: The Continued Limits Of International Criminal Justice Without A Permanent Prison System, Meg Penrose Dec 2025

Symbolic Justice: The Continued Limits Of International Criminal Justice Without A Permanent Prison System, Meg Penrose

Faculty Scholarship

Many people misremember Nuremberg, Tokyo, and the subsequent World War II tribunals. These seminal international tribunals gave the world convictions but largely failed to fully enforce the sentences imposed. Most people do not recall the mass clemency following the World War II tribunals. This Article seeks to fill a scholarly void by explaining why international criminal justice has never matured beyond Nuremberg and Tokyo. The modern ad hoc tribunals, as well as the permanent International Criminal Court (“ICC”), have failed to deliver lasting justice. Much like Nuremberg and Tokyo, the modern tribunals fixate on arrests and convictions and then seemingly …


Structural Challenges In Tvet-Industry Collaboration: A Social Justice Lens, Nthako M. Dorothy, Shuti Steph Khumalo Dec 2025

Structural Challenges In Tvet-Industry Collaboration: A Social Justice Lens, Nthako M. Dorothy, Shuti Steph Khumalo

Journal of Research in Technical Careers

Technical and Vocational Education and Training (TVET) is critical and indispensable in ensuring that the socio-economic inequalities and challenges facing not only South Africa, but also Africa, are reduced. This can be achieved by providing access to skills development, particularly for previously and historically marginalized sections of society, such as the youth. The main aim of this examination was to explore TVET collaboration with industry in promoting social justice. Social justice is deployed as a theoretical lens since social justice and education are characterized by a symbiotic relationship. In its investigation, we employed the qualitative case study approach, which involved …


When Thermal Risk Indices Work And When They Don't: A Case Study Of Two Maize Insect Pests, Komi Mensah Agboka, Frank Thomas Ndjomatchoua, Luca Rossini, Ritter A. Guimapi, Elfatih M. Abdel-Rahman Dec 2025

When Thermal Risk Indices Work And When They Don't: A Case Study Of Two Maize Insect Pests, Komi Mensah Agboka, Frank Thomas Ndjomatchoua, Luca Rossini, Ritter A. Guimapi, Elfatih M. Abdel-Rahman

All Peer-Reviewed Publications

The biological life cycle of terrestrial arthropods, using temperature as the primary driving factor has a large interest for insect pests in agriculture, forestry, urban ecosystems, as constitutes the basics for the development of mathematical models for decision making. A recent study proposed a physiologically-based risk index (RI) which finds large applications in the definition of risk maps; however, further case studies are needed to better explore its strengths and limitations. This study aims to extend this knowledge by presenting an application of the RI on two economically significant pests: the fall armyworm Spodoptera frugiperda and the stem borer Busseola …


Deepening Our Understanding Of Resilience: How Evaluation Can Contribute, Michael Quinn Patton Dec 2025

Deepening Our Understanding Of Resilience: How Evaluation Can Contribute, Michael Quinn Patton

The Foundation Review

Resilience is the capacity to experience a significant shock and adapt as needed to survive and move forward. The current age is one of constant system shocks economically, environmentally, and politically. Resilience becomes essential for navigating these and other risks.

Individuals, organizations, communities, and ecosystems manifest different degrees and types of resilience requiring appropriately matched evaluation responses. In considering new directions for philanthropic evaluation, this article offers for the first time an overarching framework of four different responses to system shocks and disruptions. This leads to four different evaluation criteria: continuity, adaptation, innovation, and capitulation.

In addition to the long-term …


Legitimacy, Learning, And Launch: Exploring Relationships, Community, And Connection In An Undergraduate Research Experience, Randi J. Sims Dec 2025

Legitimacy, Learning, And Launch: Exploring Relationships, Community, And Connection In An Undergraduate Research Experience, Randi J. Sims

All Dissertations

Undergraduate research experiences (UREs) are critically important methods for integrating undergraduate students into legitimate scientific practices. While widely celebrated for producing positive outcomes such as increased self-efficacy, research skills, and STEM retention, less is known about the processes through which undergraduate mentees become integrated members of their research groups and the broader scientific community. This dissertation presents findings from both a systematic literature review and a quantitative ethnographic study of a biological sciences URE at a southeastern R1 predominantly white institution (PWI). Grounded in communities of practice and legitimate peripheral participation frameworks, this study explores how undergraduate researchers build relationships, …


Accident Data Analytics And Ai-Based Auditory Enhancement For Highway Construction Safety, Thinh Nguyen Dec 2025

Accident Data Analytics And Ai-Based Auditory Enhancement For Highway Construction Safety, Thinh Nguyen

All Dissertations

This research develops data-driven and AI-enhanced approaches to improve worker safety in highway construction environments. The study integrates advanced analytics and auditory signal enhancement to identify high-risk worker behaviors and improve real-time safety warnings. The work consists of three core studies. The first study applies Sequential Pattern Mining and Social Network Analysis to more than 1,000 construction accident reports to identify high-risk worker actions and their hidden sequential relationships with accident types and consequences. These insights reveal sector-specific risk patterns, supporting the creation of targeted, data-informed safety interventions. The second study introduces an AI-based auditory enhancement model built on a …


Enhancing Teacher Planning Practices To Improve Teacher Self-Efficacy Through Professional Learning Communities, Philip L. Price Dec 2025

Enhancing Teacher Planning Practices To Improve Teacher Self-Efficacy Through Professional Learning Communities, Philip L. Price

All Dissertations

This improvement science dissertation investigated the impact of implementing Professional Learning Communities (PLC) on teacher self-efficacy at Parkway Elementary, a Title I school serving a diverse student population with historically lower academic performance. The study addressed the problem of low teacher self-efficacy, a critical factor influencing Tier 1 instructional quality and student outcomes. Utilizing the Plan-Do-Study-Act cycle, this research tested the theory that adopting a four-question framework within weekly collaborative grade-level meetings would measurably increase teacher self-efficacy. Seven teachers participated in the research, with data collected through the Teacher Sense of Efficacy Scale, semi-structured interviews, and PLC observations. Quantitative findings …


Carbon Sequestration And Greenhouse Gas Emission Dynamics Of Forage Sorghum Cultivars In Southern Texas, Kusalika Madushani Kularathna Dec 2025

Carbon Sequestration And Greenhouse Gas Emission Dynamics Of Forage Sorghum Cultivars In Southern Texas, Kusalika Madushani Kularathna

All Theses

Carbon sequestration is one of the major strategies for removing atmospheric carbon dioxide and fixing it in the soil and plants. The research study focused on the carbon sequestration and greenhouse gas dynamics of three different forage sorghum cultivars: Sugar Graze Ultra (annual), PSH20TX01 (perennial seeded), and PSH09TX15 (perennial rhizomes), in Southern Texas, where each cultivar had nine plots. The field study was conducted over two growing seasons, in 2024 and 2025, at the Prairie View A&M University research farm. Three different fertilizer rates, recommended, half-recommended, and zero fertilizer rates, were applied. Soil greenhouse gas emissions were measured using a …


World On Fire: The Hunger Games And The Rhetoric Of Revolution, Rachel Olivares Dec 2025

World On Fire: The Hunger Games And The Rhetoric Of Revolution, Rachel Olivares

Electronic Theses and Dissertations

In the decade between 2010 and 2020, more people participated in mass protests than at any other point in human history. From the Arab Spring to Occupy Wall Street and Hong Kong’s “umbrella movement,” street demonstrations exploded on a global scale. This period of global unrest coincided with another explosion: the dystopian young adult series The Hunger Games surged in popularity, quickly becoming a cultural phenomenon. Following the release of the book series and its subsequent film adaptations, The Hunger Games became a global symbol of grassroots resistance as social and political movements adopted the language and symbols of its …


A Qualitative Study On Black Women Leaders And Their Career Paths In Higher Education, Beatrice Porter Dec 2025

A Qualitative Study On Black Women Leaders And Their Career Paths In Higher Education, Beatrice Porter

Electronic Theses and Dissertations

Black women remain significantly underrepresented in senior leadership roles within higher education, especially in the presidency at historically Black colleges and universities. This qualitative phenomenological study explored the career paths and challenges Black women faced through their lived experiences in leadership roles across higher education institutions within predominantly White institutions and HBCUs. Guided by Black Feminist Thought as the theoretical lens, the study examined the intersecting barriers of race and gender that shaped the participants’ leadership trajectories in higher education. Data were collected through open-ended questionnaires, allowing participants to reflect on systemic inequities, mentorship experiences, and leadership development. Findings revealed …


Symmetry, Stability, And Robust Optimization Strategies For Nonorthogonal Multiconfiguration Self-Consistent Field Wavefunctions., Zihui Song Dec 2025

Symmetry, Stability, And Robust Optimization Strategies For Nonorthogonal Multiconfiguration Self-Consistent Field Wavefunctions., Zihui Song

Electronic Theses and Dissertations

The "different orbital different configuration" (DODC) framework is a general formulation of multireference wavefunctions that allows each configuration (determinant) to possess its own set of optimized molecular orbitals, rather than sharing a common orbital basis as in conventional orthogonal configuration interaction (CI) or Complete Active Space Self-Consistent Field (CASSCF) methods. One prominent example of the DODC framework is the Nonorthogonal Configuration Interaction (NOCI) method, which relaxes the orthogonality constraint between the orbitals of different configurations. This relaxation enables a compact yet flexible description of systems exhibiting strong correlation. By employing multiple nonorthogonal reference determinants, NOCI naturally incorporates orbital relaxation and …


Characterizing Hexavalent Chromium Neurotoxicity Across Laboratory Models., Samuel Thomas Vielee Dec 2025

Characterizing Hexavalent Chromium Neurotoxicity Across Laboratory Models., Samuel Thomas Vielee

Electronic Theses and Dissertations

Hexavalent chromium [Cr(VI)] is a ubiquitous environmental pollutant and potent toxicant. Exposure to Cr(VI) in drinking water is primarily associated with cancers, inflammation, and hepatotoxicity; however, recent studies have identified Cr(VI) as a neurotoxicant in rodent and cell culture models. The literature suggest chromium accumulates in the brain, induces widespread neurodegeneration, and alters rodent behaviors. Despite these data, we lack a detailed and consistent assessments of Cr(VI) neurotoxicity across models, and interactions between aging and Cr(VI) neurotoxicity are not reported in the literature. In this dissertation, we characterize Cr(VI) neurotoxicity across 3 laboratory models: Sprague-Dawley rats, Caenorhabditis elegans, and …


Staying Ahead Of The Pressure: A Multimodal Intensive Care Unit Hospital-Acquired Pressure Injury Quality Improvement Project At Sutter Medical Center, Sacramento, Mijung Lim, Daniela Tobler, Raquel Youkhana Dec 2025

Staying Ahead Of The Pressure: A Multimodal Intensive Care Unit Hospital-Acquired Pressure Injury Quality Improvement Project At Sutter Medical Center, Sacramento, Mijung Lim, Daniela Tobler, Raquel Youkhana

ELMSN E-Portfolio. A collection of Scholarly and Creative Works

Background: Hospital-acquired pressure injuries (HAPIs) are a major quality and safety concern, particularly in the intensive care units (ICUs) where critically ill and immobile patients face elevated risk. At Sutter Medical Center Sacramento (SMCS), nine confirmed HAPIs and two under investigation were reported within the medical ICU, cardiac ICU, and neurosurgical ICU by May 2025, exceeding the hospital’s target and prompting a system-wide quality improvement initiative.

Aim: The aim of this project was to: (a) reduce ICU-acquired HAPIs to fewer than four cases per quarter by December 2025 and (b) increase nursing compliance with early and ongoing prevention strategies, including …


Losing Control: Evaluative Access And The Limits Of Attributability In Angela Smith’S Theory Of Moral Responsibility, Henry Kissam Dec 2025

Losing Control: Evaluative Access And The Limits Of Attributability In Angela Smith’S Theory Of Moral Responsibility, Henry Kissam

Honors Theses

The unwilling addict agent archetype–who wholeheartedly resolves to abstain from taking a drug but takes it regardless–is important to moral responsibility theorists for many reasons, but two in particular stand head-and-shoulders above the rest. The first is the frequency with which the archetype must be reckoned with through our everyday practices of moral assessment. It is not an idle thought experiment, pushing nothing but the theoretical limits of a particular theory. It is a near-ubiquitous presence in real, practical moral assessment. The second reason is a consequence of the first. Because we deal with the archetype frequently, we morally assess …


Cool As An Aesthetic Quality, James Kirwan Dec 2025

Cool As An Aesthetic Quality, James Kirwan

Contemporary Aesthetics (Journal Archive)

To find a thing cool is to see it as the expression (directly, analogically, or by association) of a certain kind of character. It is primarily attributed to human beings perceived as autonomous to an enviable degree: indifferent to emotions that the perceiver experiences as oppressive. This grounding of cool in the attribution of an intrinsic quality to a person is revealed by the way the attribution may be checked by a perception of effort, vulnerability, or insensibility in their behavior. Objects other than human beings appear cool either by analogy or association with this primary attribution. In finding someone …


Examining The Relationship Between Cultural Competency And Teacher Preparation For Ethnic Studies: The Role Of Unconscious Bias, La Taschya Renee Harris Dec 2025

Examining The Relationship Between Cultural Competency And Teacher Preparation For Ethnic Studies: The Role Of Unconscious Bias, La Taschya Renee Harris

Graduate Theses and Dissertations

This study examines the relationship between cultural competency and teacher preparedness for Ethnic Studies, and seeks to understand whether unconscious bias influences that relationship. California’s Assembly Bill 101 mandates that all high school seniors take Ethnic Studies as a graduation requirement. Los Angeles Unified School District is the largest school district in California, the second largest in the U.S., and the fifth most segregated school district in the nation. With 44% of White high school teachers in Los Angeles Unified School District situated in the north region and a significantly less presence throughout the other three regions, the question of …


Bridging The Gap: Enhancing Institutional Support For Adjunct Faculty In Rural Community Colleges, Emily Joleen Mason Dec 2025

Bridging The Gap: Enhancing Institutional Support For Adjunct Faculty In Rural Community Colleges, Emily Joleen Mason

Graduate Theses and Dissertations

Adjunct faculty constitute approximately 70% of the academic workforce in U.S. higher education, yet they often face challenges related to professional isolation, limited institutional support, and insufficient onboarding. This qualitative study explores how institutional connectedness influences adjunct faculty retention at a rural community college in the Midwest. Using a phenomenological approach, the research investigates the lived experiences of adjunct faculty, focusing on onboarding processes, professional development opportunities, and institutional culture. Findings highlight the critical role of structured onboarding, mentorship, and continuous professional development in fostering engagement and retention among adjunct faculty. The study underscores the importance of inclusive institutional practices …


Hyperspectral Indicators And Characterization Of Glyphosate-Induced Stress In Common Lambsquarters (Chenopodium Album L.), Mario Andrés Soto Valencia Dec 2025

Hyperspectral Indicators And Characterization Of Glyphosate-Induced Stress In Common Lambsquarters (Chenopodium Album L.), Mario Andrés Soto Valencia

Graduate Theses and Dissertations

Hyperspectral sensing enables detection of herbicide stress in weeds, but practical use requires strategies for redundancy control, rating variability management, and evaluator bias mitigation. This thesis evaluates common lambsquarters (Chenopodium album) under glyphosate exposure, aiming to identify key wavelengths, construct vegetation indices, and improve injury modeling. Greenhouse experiments used dimensionality reduction methods (principal component analysis, Relief F, Bayesian discriminant analysis) to isolate 34 unique wavelengths from about 3,200 bands. Calibration data were collected 14 days after treatment (DAT) to support wavelength selection and model development, while data from 27 DAT were used for independent validation. Class comparisons across six statistically …


Educational Freedom In The United States: Democracy, Pandemic Learning, And Family Choices, Daion Lamont Daniels Dec 2025

Educational Freedom In The United States: Democracy, Pandemic Learning, And Family Choices, Daion Lamont Daniels

Graduate Theses and Dissertations

This dissertation explores the relationships among educational freedom, democratic outcomes, and family choice in the United States. Through three complementary studies, it examines how school choice interacts with civic education, student achievement, and parental behavior. Together, these studies provide a comprehensive view of how educational freedom is reshaping American schooling. The first study investigates whether private schooling supports or undermines democratic values. Using survey data from students in both private and public schools, it finds that private school students demonstrate stronger knowledge of American government and greater support for democratic norms. These results suggest that private schools may play a …


National Hero And Water Deity: The Worship Of Triệu Việt Vương In The Red River Delta, Vietnam, Huong Thi Nguyen Dec 2025

National Hero And Water Deity: The Worship Of Triệu Việt Vương In The Red River Delta, Vietnam, Huong Thi Nguyen

Graduate Theses and Dissertations

In my dissertation, the theory of collective memory will be deployed to address many questions regarding retaining, recovering, and re-creating the worship of King Triệu Việt Vương. He was a legendary, historical king of Vietnam who supposedly lived in the 6th century. His achievements were connected to the people living in the Red River Delta in their fight against the Liang invasion. The villagers who lived near or in this area also honored him for his spiritual power. They built a small temple/ shrine right by the riverbank to worship this King. The Vietnamese dynasties, Ly (in the 11th century), …


Decorin Deficiency Promotes D-Galactose-Induced Skeletal Muscle Atrophy And Fibrosis By Regulating Itgb1/Akt/Mtor Signalling Pathway, Xiaoqin Luo, Mengxue Zhang, Lili Chen, Ruichang Wang, Jiabing Lian, Zhe Yang, Renato V. Iozzo, Jin Wang, Yan Zhang, Xiuli Bi Dec 2025

Decorin Deficiency Promotes D-Galactose-Induced Skeletal Muscle Atrophy And Fibrosis By Regulating Itgb1/Akt/Mtor Signalling Pathway, Xiaoqin Luo, Mengxue Zhang, Lili Chen, Ruichang Wang, Jiabing Lian, Zhe Yang, Renato V. Iozzo, Jin Wang, Yan Zhang, Xiuli Bi

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

BACKGROUND: Primary sarcopenia is an age-associated disorder with progressive and generalised loss of skeletal muscle strength and mass. Skeletal muscle fibrosis is one of the significant pathological manifestations of age-associated sarcopenia. Decorin, a small dermatan-sulfate proteoglycan, participates in extracellular matrix assembly. In numerous studies, the involvement of decorin is not restricted to matrix structural proteins, and it also affects a diverse variety of biological functions like cell growth, adhesion, migration, proliferation and differentiation. Additionally, it modulates the process of inflammation and fibrillogenesis. Based on these preclinical evidences, we hypothesised that decorin may potentially play an important role in skeletal muscles …


"Forgive Our Living And Our Dead": Colonial Warfare In The Philippines, Mattie Fitzpatrick Dec 2025

"Forgive Our Living And Our Dead": Colonial Warfare In The Philippines, Mattie Fitzpatrick

History

In March of 1906, American troops massacred over 1,000 Filipino civilians on Bud Dajo mountain. American service members were commended for this incident. My research examines this massacre to ask why wars of insurgency are specifically subject to abuses of power, particularly during the American-Philippines War and the ensuing colonial warfare between 1898 and 1906 under the colonization of the US. My research will focus on the circumstances created to excuse US soldiers after atrocities were committed and the colonial attitudes of the time in addition to the brutal methods used by the American government in Philippines. American colonial administrators …


The Messenger, Vol. 52, No. 2 Dec 2025

The Messenger, Vol. 52, No. 2

The Messenger (archival - 1870-)

No abstract provided.


Does Investing In Schools Reduce Violent Crime?, Jamein Cunningham, Monique E. Davis, Kenneth Whaley Dec 2025

Does Investing In Schools Reduce Violent Crime?, Jamein Cunningham, Monique E. Davis, Kenneth Whaley

Presentations

No abstract provided.


The Effect Of Zakat Compliance On Institutional Performance Through Strategic Planning As A Mediating Variable: An Applied Study At The General Authority Of Zakat, Yemen, Ali Nasser Al-Ahnomi Dec 2025

The Effect Of Zakat Compliance On Institutional Performance Through Strategic Planning As A Mediating Variable: An Applied Study At The General Authority Of Zakat, Yemen, Ali Nasser Al-Ahnomi

Journal of Economics and Administrative Sciences

This study aims to analyze the mediating role of strategic planning in the relationship between zakat compliance and institutional performance in the General Authority for Zakat in Yemen, filling a research gap in fragile environments (Bin-Nashwan et al., 2021; Bryson, 2018).  The study employed a quantitative descriptive-analytical approach using a questionnaire as a key tool which was distributed to all administrative and functional leaders in the Authority and its branch in the capital, Sana'a, totaling 515, thereby representing a comprehensive survey of the research community. A total of 417 questionnaires were received. However, 398 were valid for final statistical analysis. …


Female Politicians And Corruption In Rural India, Somdeep Chatterjee, Shiv Hastawala, Elisa Taveras Dec 2025

Female Politicians And Corruption In Rural India, Somdeep Chatterjee, Shiv Hastawala, Elisa Taveras

School of Economics and Finance Faculty Publications

This paper leverages random assignment of female quotas for leadership positions on Indian village councils to assess its causal effect on corruption. Since the mid-1990s, India has mandated that at least one third of village council chief positions be randomly reserved for women. Using data from the Rural Economic and Demographic Survey (REDS) 2006, we find that an additional term reserved for a female head as opposed to just a single one reduces both the occurrence and bribe amounts paid to the local government by households. This reduction is also observed in bribes paid to other local officials suggesting downstream …


Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells For Parkinson's Disease: A Randomized Trial., Mya C Schiess, Jessika Suescun, Juan D Martinez-Lemus, Charles Green, Tia S Thomas, Mohammad Shahnawaz, Emily Tharp, Nikunj B Satani, Jerome G Saltarrelli, Christopher Adams, Marie-Francoise Doursout, Vanessa Thyne, Rula Abuamouneh, Elsa M Rodarte, Sean I Savitz, Timothy M Ellmore Dec 2025

Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells For Parkinson's Disease: A Randomized Trial., Mya C Schiess, Jessika Suescun, Juan D Martinez-Lemus, Charles Green, Tia S Thomas, Mohammad Shahnawaz, Emily Tharp, Nikunj B Satani, Jerome G Saltarrelli, Christopher Adams, Marie-Francoise Doursout, Vanessa Thyne, Rula Abuamouneh, Elsa M Rodarte, Sean I Savitz, Timothy M Ellmore

Faculty, Staff and Student Publications

Background: Neuroinflammation contributes to Parkinson's disease (PD) progression and motor dysfunction. Allogeneic human mesenchymal stem cells (allo-hMSCs) may reduce neuroinflammation and improve motor symptoms.

Objectives: To evaluate the efficacy of repeated intravenous doses of 10 × 106/kg allo-hMSCs in improving motor symptoms in patients with PD (PwP).

Methods: In this phase 2, randomized, placebo-controlled trial (November 2020-July 2023), mild-to-moderate PwP received either three allo-hMSC infusions, one placebo followed by two allo-hMSC infusions, or three placebo infusions at 18-week intervals. Follow-up lasted 88 weeks. The primary outcome was a >70% posterior probability (PP) of a difference in the proportion of participants …