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Faculty Senate Minutes, Georgia Southern University, Faculty Senate Sep 2025

Faculty Senate Minutes, Georgia Southern University, Faculty Senate

Faculty Senate Minutes

No abstract provided.

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Development And Validation Of Susceptibility Assessment Tool In Homoeopathy (Sath) In Homoeopathic Clinical Practice, Divya Taneja, Anil Khurana, Kumar Dhawale, Renu Mittal, Padmalaya Rath, Abhijit Chakma, P. Dastagiri, Pritha Mehra, Hima Bindu Ponnam, Sunil Bhalinge, Rahul Suryavanshi, Sudha Dharmarajan, Parthasarathi Chakraborty, Pooja Kumari, Priyanka Nim, Subhash Kaushik Sep 2025

Development And Validation Of Susceptibility Assessment Tool In Homoeopathy (Sath) In Homoeopathic Clinical Practice, Divya Taneja, Anil Khurana, Kumar Dhawale, Renu Mittal, Padmalaya Rath, Abhijit Chakma, P. Dastagiri, Pritha Mehra, Hima Bindu Ponnam, Sunil Bhalinge, Rahul Suryavanshi, Sudha Dharmarajan, Parthasarathi Chakraborty, Pooja Kumari, Priyanka Nim, Subhash Kaushik

Indian Journal of Research in Homoeopathy

Background: The homoeopathic philosophy identifies susceptibility as a key concept for prescribing a similimum, i.e., the indicated remedy and its potency. No validated instrument to measure susceptibility as high, medium or low could be identified in the literature. Objective: The present study was undertaken to identify the factors governing susceptibility assessment and to develop a simple tool for physicians to assess the susceptibility of the cases they see in their clinical practice. Material and Methods: A new questionnaire was developed using standardised procedures including item development, pilot testing, and psychometric evaluation. The psychometric properties of this pilot tool were assessed …

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Lm Potency Of Calcarea Carbonica For Individualised Homoeopathic Treatment Of Polycystic Ovarian Syndrome: A Case Report, Rayba Khatoon, Sumanta Kamila, Sanjay Sarkar, Javed Aquatar Bappa Sep 2025

Lm Potency Of Calcarea Carbonica For Individualised Homoeopathic Treatment Of Polycystic Ovarian Syndrome: A Case Report, Rayba Khatoon, Sumanta Kamila, Sanjay Sarkar, Javed Aquatar Bappa

Indian Journal of Research in Homoeopathy

Introduction: Polycystic ovarian syndrome (PCOS) stands as a prevalent and diverse endocrine disorder affecting women in their reproductive years. It manifests through various clinical symptoms such as oligo-anovulation, polycystic ovaries, and symptoms due to elevated serum androgen levels. Amidst the frequent side effects and limited long-term efficacy of conventional treatments, there is a growing interest in complementary therapies that can alleviate PCOS symptoms without adverse impacts. Homoeopathy, known for its individualised approach and success in treating various conditions, including PCOS, emerges as a hopeful solution. This case report aims to showcase the favourable results attained through individualised homoeopathic treatment not …

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Indian Standard Of Plastic Containers And Closures For Dispensing Homoeopathic Pharmaceutical Preparations, Homoeopathy Sectional Committee, Ayush Department, Bureau Of Indian Standards, New Delhi, India Sep 2025

Indian Standard Of Plastic Containers And Closures For Dispensing Homoeopathic Pharmaceutical Preparations, Homoeopathy Sectional Committee, Ayush Department, Bureau Of Indian Standards, New Delhi, India

Indian Journal of Research in Homoeopathy

Homoeopathic medicines require safe packaging to maintain their quality and effectiveness. Proper packaging prevents contamination, preserves potency, and ensures patient safety. Hence, Bureau of Indian Standards (BIS) had received the proposal from the Ministry of Ayush for the development of BIS standards for packaging material used for homoeopathic medicinal products (HMP). One such packaging is plastic containers. Accordingly, IS 19084: 2024 was developed and notified, which specifies requirements for plastic containers and closures used for packaging, storage, and dispensing of homoeopathic pharmaceutical preparations in solid and liquid dosage forms. This paper reports the details of the standard and the methodology …

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Exploring Underrepresented Stem Undergraduates' Stem Identity Development: The Role Of Social Partners, Sandy Cerda-Lezama Sep 2025

Exploring Underrepresented Stem Undergraduates' Stem Identity Development: The Role Of Social Partners, Sandy Cerda-Lezama

Dissertations and Theses

This dissertation employs a three-study qualitative design to investigate the role of mentorship and social interaction in the identity development of racial minority undergraduate students in STEM disciplines. Grounded in Communities of Practice theory, this research amplifies student narratives to elucidate the relational and contextual factors that inform science identity, belonging, competence, and persistence in higher education. Study One draws upon interview data from fifteen participants in the BUILD program to analyze the role of recognition, particularly from expert scientists--in students' science identity development. This study aims to understand how racial and ethnic identity intersections influence the processes and impact …

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Refractory Cutaneous Symptoms In Systemic Mastocytosis, Laura Gleason, Safiyyah Bhatti, Molly Wallace, Jason B. Lee, Onder Alpdogan, Neda Nikbakht Sep 2025

Refractory Cutaneous Symptoms In Systemic Mastocytosis, Laura Gleason, Safiyyah Bhatti, Molly Wallace, Jason B. Lee, Onder Alpdogan, Neda Nikbakht

Department of Dermatology and Cutaneous Biology Faculty Papers

No abstract provided.

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Why Explaining The Impact Of Excluding Preexisting Conditions From A Health Insurance Policy Is So Difficult: Experimental Evidence And Policy Implications, Ira M. Ellman, Ahmed E. Taha, Michael J. Saks, Mark A. Hall Sep 2025

Why Explaining The Impact Of Excluding Preexisting Conditions From A Health Insurance Policy Is So Difficult: Experimental Evidence And Policy Implications, Ira M. Ellman, Ahmed E. Taha, Michael J. Saks, Mark A. Hall

NULR Online

No abstract provided.

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Green Synthesis Of Copper And Silver Nanostructured Particles From Eremurus Plant Extract And Comparison Of Their Optical Properties And Antibacterial Activities, Doaa Ayad Kamil, Ali F. Al-Rawaf, Mohammed Yarub Hani, H.H. Obeed, Tabarek Falah Deindee, Mohammed Ridha Shaeed Sep 2025

Green Synthesis Of Copper And Silver Nanostructured Particles From Eremurus Plant Extract And Comparison Of Their Optical Properties And Antibacterial Activities, Doaa Ayad Kamil, Ali F. Al-Rawaf, Mohammed Yarub Hani, H.H. Obeed, Tabarek Falah Deindee, Mohammed Ridha Shaeed

Karbala International Journal of Modern Science

In the present investigation, silver (Ag) and copper (Cu) nanostructured particles were synthesized from Eremurus plant by means of an environmentally benign methodology in which plant extracts served as both reducing and stabilizing agents. The resultant nanostructured particles were subjected to characterization techniques, including X-ray diffraction (XRD), Fourier-transform infrared spectroscopy (FTIR), field-emission scanning electron microscopy (FESEM), and energy-dispersive X-ray spectroscopy (EDXS). XRD analysis confirmed development of Ag nanostructured particles with face-centered cubic (fcc) structure and also Cu nanostructured particles with cubic form. Moreover, the average crystallite dimensions obtained for Ag and Cu were 18.3 nm and 65.7 nm, …

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Qualities Of An Effective Mentor In Clinical Practice: Insights From Nurses And Midwives In Rwanda, Yvonne Kasine Sep 2025

Qualities Of An Effective Mentor In Clinical Practice: Insights From Nurses And Midwives In Rwanda, Yvonne Kasine

International Nursing Research Congress (INRC)

Introduction: Globally, many countries have adopted mentorship programs to support new and less experienced nurses in enhancing their skills (Hoover et al., 2020). In Rwanda, mentorship has been a part of the professional development of nurses and midwives (Musabwasoni et al., 2020; Nyiringango et al., 2021). Mentorship offers numerous benefits, serving as a tool for professional growth and fostering camaraderie among nursing and midwifery professionals. From 2016 to 2020, a clinical mentorship program named Training, support, and Access Modal (TSAM) was implemented to help nurses and midwives improve their competencies in providing maternal and neonatal care at selected health facilities …

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Improving Fatigue Strength And Life Of Single Crystal Cmsx-4, Jochen Peter Fuhr, Lloyd Hackel, Nicolau I. Morar, Noah Holtham, Keivan Davami, Montu Sharma, Rajkumar Roy Sep 2025

Improving Fatigue Strength And Life Of Single Crystal Cmsx-4, Jochen Peter Fuhr, Lloyd Hackel, Nicolau I. Morar, Noah Holtham, Keivan Davami, Montu Sharma, Rajkumar Roy

15th International Conference on Shot Peening

The deep penetration of laser peening (LP) and retention of residual stress at high temperature by LP is significant in improving fatigue life and strength of superalloys exposed to high temperature and corrosion. Single crystal CMSX-4, was evaluated for stress relaxation and both fatigue life and fatigue strength of material that was LP-treated compared to non-LP and shot-peened (SP) specimens. LP was done with multiple layers using a 20 J/pulse laser where the laser high energy enabled using a 5 mm spot size on the metal surface. Stress measurements by the slitting technique showed the plastic penetration depth exceeded SP …

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Systematic Exploration Of Trpv6 Variants In Pancreatitis: Unraveling Genetic Associations And Pathophysiological Insights Through Comprehensive Systematic Review And In-Silico Analysis, Omar Alomari, Rumeysa Yegin, Muhammed Edib Mokresh, Ghazaleh Kokabi Ghahremanpour, Nurullah Komurcu, Elif Nur Ari, Magda Wojtara, Ali Karaman, Abdulqadir J. Nashwan Sep 2025

Systematic Exploration Of Trpv6 Variants In Pancreatitis: Unraveling Genetic Associations And Pathophysiological Insights Through Comprehensive Systematic Review And In-Silico Analysis, Omar Alomari, Rumeysa Yegin, Muhammed Edib Mokresh, Ghazaleh Kokabi Ghahremanpour, Nurullah Komurcu, Elif Nur Ari, Magda Wojtara, Ali Karaman, Abdulqadir J. Nashwan

Journal of Pediatric Genetics

Background and Aims: The transient receptor potential vanilloid subfamily member 6 (TRPV6), a calcium-selective channel, is crucial for intracellular calcium (Ca2+) transport, impacting the maintenance of Ca2+ homeostasis in the pancreas. Variants in the TRPV6 gene have been associated with disruptions in calcium balance, potentially contributing to chronic pancreatitis (CP). This systematic review aims to unravel the connections between TRPV6 gene variants and pancreatitis, with a particular focus on CP. Additionally, we conducted an in-silico co-expression analysis to explore the interrelationships among validated genetic variants associated with pancreatitis pathophysiology and TRPV6 gene variants . Methods: A comprehensive literature search was …

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Bard College: An Ecosystem Of Engagement, Jonathan Becker Sep 2025

Bard College: An Ecosystem Of Engagement, Jonathan Becker

Journal of Community Engagement and Higher Education

Despite its moderate size and rural location, Bard’s civic engagement efforts resonate locally, nationally, and internationally, and have significant public policy impacts. Bard has achieved success by making engagement central to its institutional mission, viewing liberal arts and sci-ences education as both a means and an end of civic engagement efforts, and forging an “ecosystem of engagement” that encourages organizational engineers, links student-led and in-stitutional initiatives, and unites a network of partners across the globe.

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An Online Scientific Twitter World: Social Network Analysis Of #Sciencetwitter, #Scicomm, And #Academictwitter, Man Zhang, Lisa Lundgren, Ha Nguyen Sep 2025

An Online Scientific Twitter World: Social Network Analysis Of #Sciencetwitter, #Scicomm, And #Academictwitter, Man Zhang, Lisa Lundgren, Ha Nguyen

Instructional Technology and Learning Sciences Student Research

Understanding who makes up online affinity spaces as well as how information flows within those spaces is important as more people access news, research topics, collaborate with others, and entertain themselves. During a month-long period in summer 2021, we collected 100,000 tweets from 53,311 Twitter users who used the hashtags #ScienceTwitter, #SciComm, and #AcademicTwitter. We then classified users and determined the type of social network they formed. Scientists, the public, and educators formed this affinity space. They built connections by initiating activities and interacting with others, which created a Community Clusters social network structure, characterized by several medium-sized groups of …

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Campus Assembly Minutes 09/23 & 09/25/2025, Campus Assembly Sep 2025

Campus Assembly Minutes 09/23 & 09/25/2025, Campus Assembly

Campus Assembly

No abstract provided.

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Usa V. Sean Jelen Sep 2025

Usa V. Sean Jelen

2025 Decisions

USDC for the Middle District of Pennsylvania

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1064 Cauldwell Llc V. Montero Sep 2025

1064 Cauldwell Llc V. Montero

All Decisions

The landlord commenced a nonpayment summary eviction proceeding. The tenant moved to dismiss, asserting the rent demand was defective for failing to credit earmarked HRA payments. The landlord cross-moved to amend the petition. The court granted the tenant's motion and dismissed the proceeding without prejudice, finding the rent demand defective. The omission of HRA payments, representing 17% of the alleged arrears, was deemed more than a de minimis miscalculation and failed to properly apprise the tenant of the amount due. The court denied the landlord's cross-motion to amend, holding that a defective predicate notice is not amendable.

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Usa V. Cushmir Mcbride Sep 2025

Usa V. Cushmir Mcbride

2025 Decisions

USDC for the Eastern District of Pennsylvania

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Quality Improvement Project Using Standardized Teaching Tools To Improve Skills Proficiency, Katrina Walker Sep 2025

Quality Improvement Project Using Standardized Teaching Tools To Improve Skills Proficiency, Katrina Walker

Doctor of Nursing Practice Projects

Studies show that inconsistencies in teaching and evaluating skills proficiency in nursing programs can lead to student failure, delayed progression, and decreased faculty satisfaction. The purpose and aim of this quality improvement project was to determine whether the use of an evidence-based, standardized tool for teaching and evaluating Foley catheter insertion improved faculty satisfaction and teaching confidence compared to faculty-created checklists. The project utilized a quasi-experimental design guided by the Iowa Model of Evidence-Based Practice and Kotter’s 8-Step Change Model. The Bachelor of Science in Nursing (BSN) faculty implemented the standardized tool and completed pre- and post-intervention Likert-scale surveys measuring …

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Effect Of Clays On The Spontaneous Imbibition Behavior Of Surfactant Solutions In Shale Oil Reservoirs, Ning Xu, Yanling Wang, Baojun Bai, Chuanbao Zhang, Shizhang Cui, Yu Zhang, Di Li, Wenjing Shi, Wenhui Ding Sep 2025

Effect Of Clays On The Spontaneous Imbibition Behavior Of Surfactant Solutions In Shale Oil Reservoirs, Ning Xu, Yanling Wang, Baojun Bai, Chuanbao Zhang, Shizhang Cui, Yu Zhang, Di Li, Wenjing Shi, Wenhui Ding

Geosciences and Geological and Petroleum Engineering Faculty Research & Creative Works

Surfactant-enhanced spontaneous imbibition is a proven method of enhancing oil recovery from shale reservoirs. However, a significant knowledge gap concerning the impact of clay minerals on surfactant-enhanced imbibition in shale reservoirs remains. Therefore, this study first analyzed the mineral composition and pore structure of the shale reservoirs. Subsequently, three surfactants were selected for spontaneous imbibition experiments. The influence of various clay minerals on the surfactant imbibition was assessed by considering various properties of the imbibition system. The results showed that the shale pores primarily consisted of macropores (44.03%) and mesopores (43.94%). Surfactants enhance the imbibition recovery by altering the wettability …

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Fourth Amended Joint Plan Sep 2025

Fourth Amended Joint Plan

Catholic Dioceses in Bankruptcy

No abstract provided.

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Unlocking Citizen Confidence: Examining Trust And Continuance Intentions In Digital Services, Muhammad Ovais Ahmad, Iftikhar Ahmed, Osama Al-Baik, Abdelrahman Hamza Hussein, Mwaffaq Ahmad Abu Alhaija, Abdullah Albizri Sep 2025

Unlocking Citizen Confidence: Examining Trust And Continuance Intentions In Digital Services, Muhammad Ovais Ahmad, Iftikhar Ahmed, Osama Al-Baik, Abdelrahman Hamza Hussein, Mwaffaq Ahmad Abu Alhaija, Abdullah Albizri

Department of Information Management and Business Analytics Faculty Scholarship and Creative Works

Purpose – This study aims to examine the factors that influence citizens intention to continue using e-government services in Pakistan. Design/methodology/approach – Data were collected through an online survey of 641 Pakistani citizens. The responses were analyzed using partial least squares structural equation modeling. Findings – This study shows that disposition to trust positively correlates with both trust in the internet and trust in government. Notably, citizens’ satisfaction, perceived usefulness, confirmation of expectations and perceived risk significantly influence their intention to continue using e-government services. Trust in the internet emerged as a significant predictor of continuance intention, while trust in …

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Comparison Fourth Amended Joint Plan Sep 2025

Comparison Fourth Amended Joint Plan

Catholic Dioceses in Bankruptcy

No abstract provided.

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Mt1-Mmp Inhibition Rejuvenates Ageing Brain And Rescues Cognitive Deficits In Obesity, Pallavi Asthana, Liguo Li, Lin Lu, Jiayan Wu, Shuo Zhang, Ningning Li, Sheung Kin Ken Wong, Susma Gurung, Yijing Zhang, Yuwan Lin, Yufeng Peng, Zongtang Xu, Kui Ming Chan, Lixiang Zhai, Aiping Lyu, Zhao-Xiang Bian, Xin Ge, Ashok Iyaswamy, Min Li, Ya Su, Zhongjun Zhou, Pingyi Xu, Hoi Leong Xavier Wong Sep 2025

Mt1-Mmp Inhibition Rejuvenates Ageing Brain And Rescues Cognitive Deficits In Obesity, Pallavi Asthana, Liguo Li, Lin Lu, Jiayan Wu, Shuo Zhang, Ningning Li, Sheung Kin Ken Wong, Susma Gurung, Yijing Zhang, Yuwan Lin, Yufeng Peng, Zongtang Xu, Kui Ming Chan, Lixiang Zhai, Aiping Lyu, Zhao-Xiang Bian, Xin Ge, Ashok Iyaswamy, Min Li, Ya Su, Zhongjun Zhou, Pingyi Xu, Hoi Leong Xavier Wong

The Brown Foundation: Institute of Molecular Medicine

Obesity has been linked to an increased risk of cognitive impairment and dementia in later life. Although aging and obesity are both associated with cognitive decline, it remains unclear how they interact to affect cognitive function across the lifespan and how brain function might mediate their relationship with cognition. Our previous findings and other studies have shown that membrane type 1-matrix metalloproteinase (MT1-MMP/MMP14), which increases with age, regulates energy homeostasis. Inhibiting MT1-MMP improves insulin sensitivity, reduces body fat, and lowers serum cholesterol. Here, we demonstrate that MT1-MMP links neuroinflammation to cognitive decline in aging and obesity. Inflammatory responses in the …

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The Section 32(1) Analysis: Clarifying Eldridge In Light Of York Region District School Board, Kate Glover Berger Sep 2025

The Section 32(1) Analysis: Clarifying Eldridge In Light Of York Region District School Board, Kate Glover Berger

All Papers

The Eldridge framework, a stable feature of Canadian Charter jurisprudence for decades, sets out part of the framework for determining when entities or activities qualify as “government” under section 32(1), the Charter’s application section. In light of this stability, the Supreme Court of Canada’s analysis of the section 32(1) issue in York Region District School Board v Elementary Teachers Federation of Ontario was surprising. It raised the question: Why did the Court in York Region deviate from well-settled law on the Eldridge framework and, in the process, seemingly change the framework’s thresholds? This question arises because the Court in …

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Beyond Personal Responsibility: Government Support For The Substantive Human Condition, Martha T. Mccluskey Sep 2025

Beyond Personal Responsibility: Government Support For The Substantive Human Condition, Martha T. Mccluskey

Contributions to Books

Government protection against systemic harm to human well-being is stymied by the liberal idea that power is most legitimately wielded by autonomous individuals taking personal responsibility for their substantive well-being. Instead, a robust vision of democracy and socioeconomic justice requires grounding legitimate power in institutional responsibility, replacing the formal individual actor of liberal theory with the universally embodied, embedded human subject developed in Martha Fineman’s Vulnerability Theory. This chapter connects the message of personal responsibility in neoliberal US welfare reform policies to rationales defending the government’s failure to alleviate systemic human harm in the 2008 financial crisis and the accelerating …

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Sars-Cov-2 Nsp13 Interacts With Tead To Suppress Hippo-Yap Signaling, Fansen Meng, Jong Hwan Kim, Chang-Ru Tsai, Jeffrey D Steimle, Jun Wang, Yufeng Shi, Rich G Li, Bing Xie, Vaibhav Deshmukh, Shijie Liu, Xiao Li, James F Martin Sep 2025

Sars-Cov-2 Nsp13 Interacts With Tead To Suppress Hippo-Yap Signaling, Fansen Meng, Jong Hwan Kim, Chang-Ru Tsai, Jeffrey D Steimle, Jun Wang, Yufeng Shi, Rich G Li, Bing Xie, Vaibhav Deshmukh, Shijie Liu, Xiao Li, James F Martin

Faculty, Staff and Students Publications

The Hippo pathway controls organ development, homeostasis, and regeneration primarily by modulating YAP/TEAD-mediated gene expression. Although emerging studies report Hippo-YAP dysfunction after viral infection, it is largely unknown in the context of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Here, we analyzed RNA sequencing data from human-induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) and SARS-CoV-2-infected human lung samples, and observed a decrease in YAP target gene expression. In screening SARS-CoV-2 nonstructural proteins, we found that nonstructural protein 13 (NSP13), a conserved coronavirus helicase, inhibits YAP transcriptional activity independent of the upstream Hippo kinases LATS1/2. Consistently, introducing NSP13 into mouse cardiomyocytes suppresses …

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The Effect Of Moringa Oleifera Leaves Powder Increasing The Productive Characteristics Of Common Carp (Cyprinus Carpio L.) Exposed To Chlorpyrifos, Hamid Hilal Farhan, Abid Ali Thaker, Hazem Sabri Abedalhammed Sep 2025

The Effect Of Moringa Oleifera Leaves Powder Increasing The Productive Characteristics Of Common Carp (Cyprinus Carpio L.) Exposed To Chlorpyrifos, Hamid Hilal Farhan, Abid Ali Thaker, Hazem Sabri Abedalhammed

Baghdad Science Journal

Pesticides are a major global problem because of their effects on living organisms and their bodily functions. This study was conducted from August 25, 2022, to October 25, 2022. It aimed to know the toxic effects of Chlorpyrifos on common carp (Cyprinus carpio L.), and the potential of Moringa oleifera leaves to reduce this toxicity by evaluating their effect on growth performance in fish exposed to the pesticide. The LC50 for Chlorpyrifos has been estimated at 0.60 mg/L over 96 hours. Use 1/10 of the LC50 in the pesticide toxicity test treatment; Moringa leaf powder (MOL) was also added …

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Study Of Serum Interleukin-33 And Soluble St2 Levels, And Hla-B27 Typing In Iraqi Patients Of Ankylosing Spondylitis, Faris Ali Khdur, Hanaa N. Abdullah, Mayada Noori Iqbal Sep 2025

Study Of Serum Interleukin-33 And Soluble St2 Levels, And Hla-B27 Typing In Iraqi Patients Of Ankylosing Spondylitis, Faris Ali Khdur, Hanaa N. Abdullah, Mayada Noori Iqbal

Baghdad Science Journal

Ankylosing spondylitis (AS) is a type of arthritis that causes inflammation in the joints and ligaments of the spine. The current study aimed to determine the level of serum interleukin-33 (IL-33), soluble stromelysin-2 (sST2) interleukin, and HLA-B27 typing among Iraqi AS patients. The whole blood samples of the patients were collected from medical hospitals in Baghdad city. The ELISA technique was used to measure the serum levels of IL-33 and sST2, and the HLA-B27 typing was performed by sequence-specific primer PCR (SSP-PCR). The patients were divided into patients newly diagnosed with the disease and patients receiving biological treatment (etanercept) in …

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Sources, Distribution And Ecological Risk Assessment Of Polycyclic Aromatic Hydrocarbon In Sediment Of Tigris River, Iraq, Shahad R. Zaki, Maysoon Hassan Meshjel, Abdul Hameed M.J. Al-Obaidy Sep 2025

Sources, Distribution And Ecological Risk Assessment Of Polycyclic Aromatic Hydrocarbon In Sediment Of Tigris River, Iraq, Shahad R. Zaki, Maysoon Hassan Meshjel, Abdul Hameed M.J. Al-Obaidy

Baghdad Science Journal

Sediment samples were collected from five sites at Tigris River from Baghdad to Wasit Governorates River from December 2021 to November 2022. Sixteen polycyclic aromatic hydrocarbons (PAHs) in these sediment samples were analyzed. The results show that the total PAH concentrations ranged from 957.37 to 1805.05 μg/kg dry weight (dw) with mean values of 1368.034 μg/kg. Furthermore, the high molecular weight compounds (four, five, and six rings) of PAH in the analyzed sediment samples suggest that combustion sources such as fuel, gasoline, and vehicle emissions are the primary sources of PAHs in the environment. The sediment quality guidelines …

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Nrf2 Drives Activation-Driven Expansion Of Cd4+T Cells By Modulating Glucose And Glutamine Metabolism, Aprajita Tripathi, Debolina Dasgupta, Michael S. Dahabieh, Rachel Griffard-Smith, Anil Pant, Ashlyn Bugbee, Nanda Kumar Yellapu, Emily Burt, Ben H Y Choi, Abigail E. Ellis, Ryan D. Sheldon, Shailendra Giri, Devin Koestler, Russell G. Jones, Viveka Nand Yadav, Kalyani Pyaram Sep 2025

Nrf2 Drives Activation-Driven Expansion Of Cd4+T Cells By Modulating Glucose And Glutamine Metabolism, Aprajita Tripathi, Debolina Dasgupta, Michael S. Dahabieh, Rachel Griffard-Smith, Anil Pant, Ashlyn Bugbee, Nanda Kumar Yellapu, Emily Burt, Ben H Y Choi, Abigail E. Ellis, Ryan D. Sheldon, Shailendra Giri, Devin Koestler, Russell G. Jones, Viveka Nand Yadav, Kalyani Pyaram

Manuscripts, Articles, Book Chapters and Other Papers

Upon antigenic stimulation, CD4+T cells undergo clonal expansion elevating their bioenergetic demands and utilization of nutrients like glucose and glutamine. The nuclear factor erythroid-2-related factor 2 (Nrf2) is a well-known regulator of oxidative stress, but its involvement in modulating the metabolism of CD4+T cells remains unexplored. We report that Nrf2 protein levels are temporally regulated in activated CD4+T cells, with elevated expression during early activation followed by a decline. T cell-specific constitutive activation of Nrf2, by deletion of its negative regulator Keap1, enhances early activation and interleukin-2 (IL-2) expression, upregulates T cell receptor (TCR) signaling, and increases activation-driven expansion of …

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