Digital Commons Network^™

Multimodal Late-Fusion Of Radiomics, Clinical Data, And Demographics Enhances Personalized Survival Prediction In Nsclc, Zarindokht Helforoush, Mohamed Jaber, Nezamoddin N. Kachouie

Mathematics and System Engineering Faculty Publications

Backgrounds/Objectives: Non-small cell lung cancer (NSCLC) exhibits substantial prognostic heterogeneity that is not fully captured by conventional anatomical staging, highlighting the need for individualized risk assessment. Radiomics enables non-invasive characterization of tumor phenotype, yet high dimensionality and inter-feature correlations often limit model stability and interpretability. Methods: To address these challenges, we developed a multimodal late-fusion framework integrating radiomic, clinical, and demographic information to predict patient-specific absolute risk in the Lung1 cohort (N = 398). Radomic features (N = 107) were extracted from primary tumor volumes and refined using a Group Lasso–penalized Cox model, preserving biological coherence and producing a parsimonious …

Tennessee Archivist 45, No. 1, Society Of Tennessee Archivists

Tennessee Archivist newsletters

Winter 2026 issue of the Tennessee Archivist, a newsletter produced by the Society of Tennessee Archivists.

The Effects Of Expectancies And Attention To Placebo Relevant Sensations On The Open-Label Placebo Response, Miranda Connelly

Cal Poly Humboldt theses and projects

Placebo analgesia has shown promise in treating pain, but practitioners are reluctant to prescribe deceptive placebos. Open-label, or honestly prescribed placebos, offer an ethical alternative. Open-label placebos seem to work largely through experimenter-manipulated expectancy, as well as social/environmental factors. Additionally, verbally guided attention to relevant placebo sensations might bolster pain relief. In the present study, expectancy and attention were experimentally manipulated within a 2 (expectancy: high/low) x 2 (attention: high/low) between-subjects design with a no-treatment comparison group. Pain was experimentally induced in all five experimental groups using the well-established cold pressor task. The primary dependent variables were pain tolerance and …

Rethinking Belonging In First-Year Student Support: A Mixed-Methods Evaluation Of Eop/Sss Programing At Cal Poly Humboldt, Elizabeth Rose Silver

Cal Poly Humboldt theses and projects

This mixed-methods project examines the role of the Educational Opportunity Program and Student Support Services (EOP/SSS) first-year orientation programs, particularly STEM Summer Bridge, in supporting feelings of belonging and persistence. While institutional efforts often frame student success through metrics such as retention and concepts like sense of belonging, this project interrogates how these are experienced and understood by students themselves. Quantitative analyses compared one-year persistence rates between STEM Summer Bridge participants and multiple comparison groups across three cohorts (2022–2024). Results showed no statistically significant differences in persistence; however, STEM Summer Bridge participants demonstrated persistence rates comparable to or slightly higher …

Development Of The Core Lit Apparatus For Seaweed Hatcheries (Clash) Bioreactor Using A Germplasm Approach, Phillip O. Tahimic

Cal Poly Humboldt theses and projects

In comparison to the Asian aquaculture industry, the United States has minimal seaweed production. There are several drivers of the limited industry in the US, such as regulatory constraints and limited market demand, but the ability to scale is a considerable barrier to commercialization. One possible solution is the development of land-based systems that integrate bioreactors, which utilize fewer resources and do not wholly rely on an oceanic flow-through system. This study assessed the application of a modular bioreactor, known as Core Lit Apparatus for Seaweed Hatcheries (CLASH), as a nursery system and open-source project designed to expand land-based seaweed …

Land Cover Classification Using Optimized Imagery Resolution And Machine Learning Algorithms For A Long-Term Monitoring And Restoration Project, Jessica R. Suoja

Cal Poly Humboldt theses and projects

Ecosystem services and functions are prone to water resource exploitation resulting in cascading effects that include decrease of biodiversity and loss of riparian vegetation, a keystone habitat in desert riparian ecosystems. Mono Lake is a prime example of overexploitation of water resources leading to legal action and eventually a legally mandated long-term monitoring and restoration project. Monitoring and restoration projects can benefit from techniques such as remote sensing and machine learning algorithms to generate accurate land cover classification maps for calculating land cover change over time. However, the spatial resolution of remote sensing imagery and the machine learning algorithms chosen …

Reclaiming Presence: An Anthropological Study Of Digital Disconnection And Meaning-Making, Leslie De Paz

Cal Poly Humboldt theses and projects

Human attention is increasingly at risk in an unregulated digital ecosystem where overconsumption shapes neurological function, social interaction, and the ways people make meaning of everyday life. Dominant discourse around digital overuse tends to medicalize the problem, framing it as individual addiction or clinical dysfunction. In this thesis, I argue that such framing obscures what a cultural phenomenon is fundamentally, one in which people are actively questioning their relationship with technology, building awareness, and developing practices that help them slow down and reclaim agency within algorithmically mediated environments. This study draws on 22 semi-structured interviews with Gen Z and millennial …

Front Matter

Journal of Air Law and Commerce

No abstract provided.

Legal Turbulence: Addressing Unresolved Questions In Civil Aviation Through Judicial Adjudication, Arthur Shirichena

Journal of Air Law and Commerce

The increasing complexity of international civil aviation has outpaced the mechanisms currently available for the peaceful resolution of disputes. While aviation has long been governed by treaties such as the Chicago Convention of 1944 and managed through institutions like the International Civil Aviation Organization (ICAO), many emerging issues remain unresolved by these frameworks. Questions concerning the interaction between aviation and competition law, the legality of air blockades and no-fly zones, and the definitional ambiguities surrounding dual-use technologies such as weaponized aircraft or unmanned aerial systems have created pressing normative and jurisdictional challenges. This Paper argues that the establishment or empowerment …

Void In Space: How Loper Bright And The Major Questions Doctrine Affect The Federal Communications Commission’S Regulatory Authority Of Orbital Debris, Hernan Valles

Journal of Air Law and Commerce

Since the dawn of the space race, countries have been reaching for the stars. Recently, companies have joined the race. The space race and technological advancement of near-Earth orbital satellites have caused a buildup of debris in near-Earth orbit. The exponential increase of orbital debris in Earth’s orbit threatens the environmental system of the planet, the safety of astronauts aboard the International Space Station, the structure of other spacecraft, and modern economies relying on operational satellites to provide rapid communication, navigation, and weather forecasting information.

Yet there is a void among U.S. regulators in setting rules that mitigate orbital debris …

Outer Space Employment Tax And Grounded Enforceability: A Node-Based Approach Under International Space Law, Binbin Guo

Journal of Air Law and Commerce

As commercial space activities move from state-led exploration to market operations, outer space is changing from a mission space into a workspace. As a result, the traditional connecting point for employment taxes, centered on the workplace, begins to lose force. This Article develops the concept of outer space employment taxation and argues that its key issue is not taxation in orbit, but enforceability. International space law does not directly provide the tax base, tax rates, or specific withholding rules. But through state responsibility, authorization and continuing supervision, and registration coupled with jurisdiction and control, it already provides institutional interfaces through …

In The Heavens As It Is On Earth: Embracing Federalism To Supervise And Promote U.S. Non-Governmental Entities’ Non-National Activities In Outer Space, Steven E. Bartz

Journal of Air Law and Commerce

Most of the law governing outer space is public international law, which applies, with limited exceptions, directly to nation-states (states) only. The application of international law to nongovernmental entities’ (NGEs), such as natural persons and companies with distinct legal personage, activities in outer space occurs through a state’s domestic legal implementation of that international law. The United States is a party to several treaties that govern the exploration and use of outer space (the Applicable Treaties), which, through the Supremacy Clause of the U.S. Constitution, become “the supreme Law of the Land.” The Applicable Treaties were written and went into …

What Is Terrorism?, Karl T. Muth, Alice Locatelli

Journal of Air Law and Commerce

Is Gotham's Joker a terrorist? What about a school shooter? As we approach the twenty-fifth anniversary of the 9/11 attacks, the United States still lacks a monolithic legal definition of 'terrorism,' creating a dangerous 'motive gap' between federal statutes. This Article analyzes the friction between the motive-heavy definition of 'domestic terrorism' in Title 18 (which includes a mens rea aspect) and the conduct-focused definition of 'terrorist activity' in Title 8 (which focuses on overt acts). Using the hijacking of Flight 93 and the Columbine shootings as case studies, we demonstrate how Title 18's political requirement creates a coverage void for …

Targeting Ptp4a3 And Kvx-053 Mitigates Alcohol-Amplified Sars-Cov-2 Spike Protein-Induced Acute Lung Injury, Pavel A. Solopov, Ruben Manuel Luciano Colunga Biancatelli, Elizabeth R. Sharlow, John S. Lazo, John D. Catavas

Bioelectrics Publications

Introduction: Chronic alcohol exposure is associated with increased vulnerability to acute respiratory distress syndrome (ARDS), and emerging evidence suggests that this susceptibility extends to the severe respiratory manifestations of COVID- 19. The SARS-CoV-2 Spike Protein S1 subunit (S1SP) can independently trigger robust inflammatory and vascular injury responses in the lung, and our prior work demonstrated that chronic alcohol consumption markedly intensifies these effects in mice. PTP4A3 phosphatase is a key regulator of inflammation and endothelial barrier function. In this study, we investigated whether the PTP4A3 inhibitor KVX-053 can counteract alcohol-enhanced S1SP-induced lung injury in K18-hACE2 mice.

Methods: Animals were maintained …

Cxcr6+ Natural Killer Cell Immunotherapy Preserves Cd4+ T Helper Cells In Humanized Mice, Naushad Khan, Kayla Frank, Silke Paust

Faculty Research 2026

Human immunodeficiency virus (HIV) persists despite antiretroviral therapy because long-lived viral reservoirs are not eliminated, and ongoing or rebound infection contributes to progressive loss of CD4⁺ T helper cells. Natural killer (NK) cells can acquire adaptive, antigen-experienced functions, including recall responses to HIV envelope protein, suggesting that defined NK-cell subsets may be therapeutically useful against HIV. Because HIV-responsive adaptive NK-cell activity is enriched among CXC chemokine receptor 6-positive (CXCR6⁺) NK cells, we tested whether CXCR6⁺ NK cells provide enhanced antiviral activity and CD4⁺ T-cell protection compared with CXCR6⁻ NK cells. In co-cultures with HIV-infected …

Can Angiotensin Ii Affect The Inflammatory Response Of Human Dental Pulp Cells In Vitro?, Bella Luna Colombini-Ishikiriama, Thiago José Dionisio, Thais Francini Garbieri, Rafaela Alves Da Silva, Sandra Helena Penha Oliveira, Vanessa Soares Lara, Andrew S Greene, Carlos Ferreira Dos Santos

Faculty Research 2026

OBJECTIVE: This study aimed to evaluate the capacity of fibroblasts from permanent and deciduous dental pulp to express inflammatory mediators when exposed to bacterial and inflammatory antigens. It also sought to assess the presence of components of the renin-angiotensin system (RAS) and the potential modulatory role of ANG-II in this response.

METHODOLOGY: Fibroblasts were cultured from the pulp of permanent and deciduous teeth obtained from three adult and four pediatric donors with informed consent. Cells were stimulated with Porphyromonas gingivalis and Escherichia coli lipopolysaccharides (LPS) either alone or in combination with ANG-II and, in some cases, with IL-1β. Gene expression …

Race And Racism In Canada’S Immigration Detention System, Efrat Arbel, Prasanna Balasundaram, Hanna Gros, Nana Yanful

All Faculty Publications

Race and Racism in Canada's Immigration Detention System is the first comprehensive, independent study to examine race and racism in Canada's immigration detention system. Grounded in rigorous legal analysis and qualitative research, the study draws on interviews with 50 participants, including people with lived experience of immigration detention, as well as lawyers, paralegals, and service providers who work in immigration detention. The research was guided by an advisory board of people with lived-experience in immigration detention and co-led by a collaborative research team.

Call Off The Dogs: Rethinking Sniffer Dog Searches In Canadian Criminal Law, Sara Gordon

All Faculty Publications

The Supreme Court of Canada has repeatedly held that police sniffer dog searches are Charter-compliant based on a low standard of reasonable suspicion because they are minimally intrusive, narrowly targeted, and can be highly accurate. Since the Court last considered their constitutionality, however, extensive empirical research has fundamentally challenged assumptions about the reliability and accuracy of police sniffer dogs, as well as the harm to individuals subjected to these searches. Moreover, the phenomenon of handler cueing can operate to transmit a police officer’s unconscious biases—even those they would consciously reject—to their dogs, further reducing accuracy and leading to false alerts …

Bloodstain Pattern Analysis And The Gatekeeping Role Of Canadian Courts, Sara Gordon

All Faculty Publications

Despite its long history of admission throughout North America, there appears to be no published Canadian case subjecting bloodstain pattern analysis to the special scrutiny Canadian law demands for novel or contested scientific evidence. Instead, courts have admitted the evidence based largely on the training and experience of forensic examiners, taking it for granted that the field is sufficiently reliable. However, the application of the White Burgess framework reveals that there are serious and severe concerns about the underlying scientific validity of the technique which should render it generally inadmissible. At Stage One of White Burgess, bloodstain pattern analysis fails …

Model Law? Template Legal Culture And The Global Production Of Environmental Law, Natasha Affolder

All Faculty Publications

Lawyers build from templates. Accounts of how law is made rarely mention them. New legislation tends to present itself as original. It is almost never made from scratch. This article makes the hidden process visible. It does so through a study of the near-global spread of environmental impact assessment (EIA) legislation since 1969, using computer-assisted textual similarity analysis to trace what I expected to be identifiable model laws and clear lines of legal inheritance. The search yielded instead a transnational repertoire of legal fragments, repeatedly recombined into new legislative forms across different legal traditions, languages and decades. EIA's legislative spread …

Good Faith And Certainty In Contract Law, Marcus Moore

All Faculty Publications

Does a general principle of good faith create too much uncertainty in  Contract Law? This article provides in-depth consideration of the controversy around this question.Reviewing a number of common arguments and reasonswhy good faith is said to be too uncertain, and responses to these, the article finds a complex picture rather than a simple answer. Recent Canadian experience with recognising a general principle of good faith in contractual performance suggests that at least two further details are critical to the potential for uncertainty: first, whether good faith operates as a freestanding duty or instead functions as a unifying principle that …

Maine Law Magazine - Issue No. 100, University Of Maine School Of Law

Maine Law Magazine

Features

• Maine Law’s Privacy Program Continues to Innovate
  How Maine Law’s privacy and innovation programs are preparing students for emerging legal challenges.

• New Business & Law Clinic
  Strengthening Maine’s economy one startup at a time.

• Global Experiential Learning
  From the Arctic Circle to U.N. climate negotiations, students engage with environmental law where it happens.

• Rural Access to Justice
  The Rural Practice Clinic’s impact on Maine’s growing justice gap.

• Law & Conservation Efforts
  How Maine Law alumni steward change and safeguard the future through environmental advocacy.

• Supporting Maine’s Vulnerable
  The Refugee & Human Rights Clinic expands access to justice across Maine. …

Early Icu Physiological Subtyping From Time-Series Data: A Comparative Study Of Feature Complexity, Predictive Performance, And Model Interpretability, Rojeena Khadka

College of Graduate Studies: Theses & Dissertations

Intensive Care Unit (ICU) patients do not follow a single uniform physiological pattern. Patients admitted with the same diagnosis show different clinical trajectories over time making standardized classification and treatment approaches insufficient. The increasing availability of large-scale electronic health records in MIMIC-IV makes it possible to investigate such heterogeneity through data-driven approach that captures how physiology evolves during the early phase of ICU admission. This thesis compares two analytical pipelines designed to identify physiological subtypes from the first 48 hours of ICU time series data. This study then assesses how well these subtypes predict in-hospital mortality. The first approach, referred …

Effects Of The Menstrual Cycle Phase On Rpe, And Symptom Characteristics In Pre-Professional Female Soccer Players, Emily Potts

College of Graduate Studies: Theses & Dissertations

Hormonal fluctuations across the distinct phases of the menstrual cycle have been shown to influence physiological and psychological responses to exercise, with some evidence suggesting phase-dependent changes in symptom presentation and ratings of perceived exertion (RPE); however, findings remain inconsistent, and few studies have examined these relationships across an entire competitive season in female soccer players. The purpose of this study was to examine changes in RPE and menstrual symptoms across cycle phases, as well as the relationships between RPE and symptom reporting in pre-professional female soccer players. A total of 22 female soccer players (age 22± 1.85) were recruited …

Effect Of Elemental Additions On The Microstructure, Macrostructure, And Mechanical Properties Of Gray Iron, August E. Rautmann

College of Graduate Studies: Theses & Dissertations

Gray iron is composed primarily of an iron matrix and flake graphite, with the higher percentage of volume taken up by the iron matrix. The iron matrix is the transformation product of austenite, and this prior austenite structure is understood to affect the final grain structure. Grain structure affects the properties of a metal, with a finer structure recognized as beneficial for most properties. Thus, the refinement of austenite structure has potential in improving the material properties of gray iron. This study aims to advance the limited knowledge about the control of austenite grain size via elemental additions. Building off …

Disrupting Ableist And Heteronormative Narratives Through The Other-Abled Body In Octavia E. Butler's "The Evening And The Morning And The Night", Morayo Joy Akingbelue

College of Graduate Studies: Theses & Dissertations

Ableist discourse has historically positioned disabled people as ‘unfit,’ resulting in their marginalization within society. This marginalization is not only manifested in terms of their physical performance but sometimes in the way disability intersects with race, gender, and sexuality, reinforcing the construction of disabled individuals as ‘other.’ While prominent feminist and disability scholars have challenged deficit based narratives of disability, Rosemarie Garland-Thomson’s concept of the misfit, Sami Schalk’s Defamiliarization, John Swain and Sally French’s Affirmative Theory, and Moya Bailey and Izetta Autumn Mobley’s A Black Feminist Disability Framework, Black women’s speculative fiction, offers a critical intervention by defamiliarizing dominant narratives …

Gauge-Invariant Gravitational Wave Polarization In Metric F(R) Gravity With Cosmological Implications, Ramesh Radhakrishnan, David Mcnutt, Delaram Mirfendereski, Alejandro Pinero, Eric Davis, William Julius, Gerald Cleaver

Physics & Astronomy Faculty Publications

We develop a fully gauge-invariant analysis of gravitational-wave polarizations in metric 𝑓⁡(𝑅) gravity with a particular focus on the modified Starobinsky model 𝑓⁡(𝑅) =𝑅 +𝛼⁢𝑅2 −2⁢Λ, whose constant-curvature solution 𝑅𝑑 =4⁢Λ provides a natural de Sitter background for both early- and late-time cosmology. Linearizing the field equations around this background, we derive the Klein–Gordon equation for the curvature perturbation 𝛿⁢𝑅 and show that the scalar propagating mode acquires a mass 𝑚2𝜓 =1/(6⁢𝛼), highlighting how the same scalar degree of freedom governs inflationary dynamics at high curvature and the propagation of gravitational waves in the current accelerating Universe. Using the scalar–vector–tensor …

Navigating Liminality: Building Resources For And With Undocumented Students, Yaneyry Delfin Martinez

Cal Poly Humboldt theses and projects

Rooted in Community-Based Participatory Research (CBPR) and Liberation Sociology, this project outlines an institutional blueprint for the resources and support systems needed to address the lived realities of undocumented students at Cal Poly Humboldt (CPH). Conducted during the second Trump Administration amidst escalating hostility towards immigrants and attacks on DEI initiatives, this work documents both the structural conditions shaping undocumented students’ lives and the collective resistance that emerged in response. Furthermore, it examines how immigration policy, access to and restrictions on federal and state aid, geographic conditions, and on-campus barriers reproduce and maintain legal liminality within higher education. Grounded in …

"What Power Do We Have?" Community Capacity And Justice In Samoa, California’S Floating Offshore Wind Terminal Development, Lauren Mccall Hart

Cal Poly Humboldt theses and projects

Floating offshore wind (OSW) is a relatively novel technology in the United States, which is positioned to play an integral role in California’s decarbonization strategy. Two federal OSW lease areas have been established off the coast of Northern California, and plans are underway to develop supporting port infrastructure, including the Humboldt Bay Offshore Wind Heavy Lift Marine Terminal (HLMT). The proposed HLMT site is adjacent to communities on the Samoa Peninsula of Humboldt Bay, which currently face socio-environmental vulnerabilities and critical infrastructure gaps. The social implications of OSW port development remain poorly understood, particularly in rural and underserved communities. This …

Ai Deployment Authorisation: A Global Standard For Machine-Readable Governance Of High-Risk Artificial Intelligence, Daniel Djan Saparning

Student Publications

Modern artificial intelligence (AI) governance lacks a formal, enforceable mechanism for determining whether a given AI system is legally permitted to operate in a specific domain and jurisdiction. Existing approaches-such as model cards, audits, and benchmark evaluations provide descriptive information about model behaviour and training data but do not produce binding deployment decisions with legal or financial force. This paper introduces the AI Deployment Authorisation Score (ADAS). This machine-readable, regulator-grade framework evaluates AI systems across five legally and economically grounded dimensions: Risk, Alignment, Externality, Control, and Auditability, derived from safety engineering, alignment theory, algorithmic accountability, and liability economics. ADAS produces …