Digital Commons Network^™

Daam2 Gene Variants P.(Asp165glu) And P.(Asn614thrfster2) In Pediatric Cryptorchidism: A Hypothesis-Generating Pilot Case-Control Study From The Eastern Black Sea Region Of Türkiye ​, Onur Yalçin, Çağri Doğan

Turkish Journal of Medical Sciences

Background/aim: Cryptorchidism is the most common congenital anomaly of the male genitourinary system, characterized by a multifactorial etiology. The disheveled-associated activator of morphogenesis 2 (DAAM2) gene regulates androgen receptor (AR)- dependent transcription; its variants are associated with partial androgen insensitivity. Since the inguinoscrotal phase of testicular descent is androgen-dependent, we hypothesized that DAAM2 variants contribute to cryptorchidism susceptibility. This pilot study, designed to generate hypotheses rather than to establish association, investigated the frequency of two functionally characterized DAAM2 variants, p.(Asp165Glu) and p.(Asn614ThrfsTer2), in pediatric cryptorchidism.

Materials and methods: This prospective case-control study included 40 male pediatric cryptorchidism patients and 39 …

A Comparative Analysis Of Clinical Quality And Readability Of Neuropathic Pain Patient Information Leaflets: Türkiye Versus The United States, Gonul Sari, Argun Pire

Turkish Journal of Medical Sciences

Background/aim: Neuropathic pain management requires high patient adherence and complex dose-titration regimens, making the readability of patient information leaflets (PILs) a critical patient safety factor. This study aimed to compare the clinical content quality and linguistic readability of PILs for neuropathic pain medications between Türkiye (TİTCK) and the United States (DailyMed).

Materials and methods: A total of 11 pairs of innovator medications were analyzed. Clinical content was assessed using the 15-item Keystone Clinical Content Checklist (KCCC). Readability was assessed using the Ateşman index for Turkish texts and the Flesch Reading Ease Score (FRES) for English texts. Information quality and reliability …

Readability Of Dermatology Patient Education Materials: A Comparative Analysis Of Turkish Dermatology Association Brochures And Texts Generated By Chatgpt And Gemini ​, Ahmet Kağan Özdemi̇r, Bengü Reyhan Botsali Özdemi̇r, Akin Aktaş

Turkish Journal of Medical Sciences

Background/aim: In modern healthcare, patient education materials (PEMs) are essential for bridging the gap between clinical knowledge and patient understanding. However, in Türkiye, where 64.6% of the adult population possesses inadequate or problematic health literacy, traditional medical brochures often exceed recommended reading levels. This study aimed to evaluate and compare the readability of Turkish dermatology PEMs prepared by the Turkish Dermatology Association (TDA) with those generated by artificial intelligence (AI) models.

Materials and methods: A total of 68 TDA PEMs were analyzed. Readability was assessed using the Ateşman Readability Index. Responses were generated by AI models to questions extracted from …

Thyroid Function In Children With Attention-Deficit/Hyperactivity Disorder And Specific Learning Disorder: A Retrospective Comparative Study, Gül Trabzon, Seda Aybüke Sari, Servet Yüce, Şeyma Demi̇ray Güllü

Turkish Journal of Medical Sciences

Background/aim: This study analyzes thyroid function parameters (free T₃, free T₄, TSH) in children with attention-deficit/hyperactivity disorder (ADHD), ADHD with specific learning disorder, and healthy controls, to determine whether subtle thyroid dysregulation contributes to the phenotypic heterogeneity of ADHD.

Materials and methods: This retrospective, cross-sectional study included 135 children aged 6–18 years: 62 diagnosed with ADHD (38 isolated ADHD and 24 ADHD+SLD) and 73 healthy controls. Demographic, anthropometric, and thyroid function data (free T₃, free T₄, TSH) were extracted from medical records. Group comparisons were conducted using independent samples t-tests, ANOVA, and ANCOVA adjusted for age, sex, and treatment status. …

Sarcopenia Risk In Women With Postmenopausal Osteoporosis: A Sarc-F-Based Assessment ​, Burak Kami̇l Turan, Ayşe Adi̇le Küçükdeveci̇, Zafer Günendi̇, Ayşegül Yaman, Oya Özdemi̇r, Jale Meray, Fatma Yeşi̇m Gökçe Kutsal

Turkish Journal of Medical Sciences

Background/aim: Osteoporosis and sarcopenia are diseases of bone and muscle tissue, respectively. Studies reported that these disorders were interrelated. However, this relation was explored in older adults and/or with certain comorbidities, and information about nonelderly postmenopausal women is scarce. This study’s objectives were to investigate the relationship between osteoporosis and SARC-F-defined sarcopenia risk in postmenopausal women aged ≤70 years and to examine the effect of other factors on this risk.

Materials and methods: This multicenter case-control study included postmenopausal women aged 45–70 years. Dual-energy X-ray absorptiometry was utilized to diagnose osteoporosis. Sociodemographic and clinical variables, sarcopenia risk (SARC-F), muscle strength …

Nationwide Characteristics Of Infectious Disease Patients Transported By Helicopter In Türkiye, Ayşe Gülden Bekgöz, Kerem Dost Bi̇lmez, Muhammed Saltuk Deni̇z

Turkish Journal of Medical Sciences

Background/aim: To evaluate the clinical, demographic, and operational characteristics of patients with infectious diseases transported by helicopter ambulance and to examine differences in the transfer patterns, flight durations, and diagnostic categories.

Materials and methods: Registry data of patients with infectious diseases transported by helicopter ambulance were analyzed. Demographic characteristics, diagnoses, referring and receiving hospital types, intraprovincial and interprovincial transfer status, flight durations, and temporal distribution of transfers (hours, days, and months) were evaluated. Flight duration was calculated in minutes and compared between intraprovincial and interprovincial transfers.

Results: A total of 543 patients with infectious diseases were transported by helicopter ambulance. …

Therapeutic Potential Of Nasal Kisspeptin-54 For Reducing Α-Synuclein Accumulation And Restoring Hippocampal Synaptic Plasticity In A 6-Hydroxydopamine-Induced Rat Model Of Parkinson’S Disease ​, Ayşegül Gemi̇ci̇ Si̇nen, Emre Savran, Okyanus Bora Güleç, Osman Si̇nen, Nari̇n Deri̇n

Turkish Journal of Medical Sciences

Background/aim: Parkinson’s disease (PD) is characterized by progressive degeneration of dopaminergic neurons and pathological aggregation of α-synuclein (α-syn), leading to significant motor and cognitive impairments. Kisspeptin-54 (KP-54), a neuropeptide primarily involved in reproductive regulation, has recently been implicated in neurorestorative processes, with emerging evidence suggesting beneficial effects on locomotor activity and cognitive function. However, its therapeutic potential in PD has not yet been fully investigated. This study aimed to evaluate the therapeutic efficacy of chronic nasal KP-54 administration in a 6-hydroxydopamine (6-OHDA) rat model of PD, focusing on motor and cognitive outcomes, hippocampal synaptic plasticity, and α-syn pathology.

Materials and …

Exploratory Evaluation Of Mir-146, Inflammatory Biomarkers, And Subjective Cognitive Symptoms In Chronic Migraine ​, Hale Gök Dağidir, Duygu Bandirmali, Merve Hi̇lal Ceren Akgör, Doğa Vuralli, Meltem Yalinay, Güvem Gümüş Akay, Hayrunni̇sa Bolay

Turkish Journal of Medical Sciences

Background/aim: Chronic migraine (CM) is a disabling neurological disorder associated with substantial impairment of quality of life. Increasing evidence suggests that inflammatory and epigenetic mechanisms may contribute to migraine pathophysiology. miR- 146, a microRNA involved in the TLR-4/NFkb pathway, is known to regulate proinflammatory signaling, whereas HMGB1 activates inflammatory pathways through TLR2 and TLR4 receptors. IL-17 is another proinflammatory cytokine implicated in both inflammation and cognitive processes. In this research, our aim was to investigate the relationship between serum HMGB1, IL-17, and miR-146 levels and migraine-related subjective cognitive symptoms in patients with CM.

Materials and methods: Serum samples were collected …

Direct Pars Repair Techniques For Lumbar Spondylolysis: A Comparative Literature Review ​, Kami̇l C. Kose, Moustafa Ibrahim, Ni̇cholas D. Haden, John Afolayan, Hanny Anwar

Turkish Journal of Medical Sciences

Background/aim: Lumbar spondylolysis, a pars interarticularis defect affecting approximately 3%–6% of the general population, presents a significant clinical challenge in young adults and athletes. When conservative management fails, direct pars repair offers an attractive alternative to spinal fusion by preserving segmental motion and reducing the risk of adjacent segment degeneration. This narrative review compares seven principal direct pars repair techniques—Buck’s technique, Scott’s wiring method, Morscher’s hook-screw system, pedicle screw-based constructs, the V-rod/U-rod (Gillet technique), the smiley face rod construct, and the dualstability construct (DSC)—evaluating their biomechanical properties, clinical outcomes, fusion rates, and complication profiles.

Materials and methods: A narrative literature …

Posttraumatic Stress In Newly Diagnosed Epilepsy: Associations With Early Maladaptive Schemas, Anxiety, And Quality Of Life In A 6-Month Prospective Study ​, Mehmet Öztürk, Pinar Öztürk, Fügen Sönmez Çeti̇nkaya, İlker Özdemi̇r

Turkish Journal of Medical Sciences

Background/aim: Epilepsy is a chronic neurological disorder that significantly affects psychosocial functioning, self-perception, and quality of life. Emerging evidence suggests that posttraumatic stress (PTS) symptoms may be more prevalent in individuals with epilepsy than previously recognized, particularly following seizure-related experiences perceived as traumatic. The aim of this study was to evaluate short- and long-term PTS levels in individuals with newly diagnosed epilepsy and examine their associations with anxiety, depression, early maladaptive schemas, and quality of life.

Materials and methods: In this prospective study, 31 individuals with newly diagnosed epilepsy were enrolled. Participants completed a sociodemographic data form, the Post-Traumatic Stress …

Enhancing Salinity Tolerance In Phyla Nodiflora L. With Potassium Humate: Crosstalk Between Osmolytes, Antioxidants, And Mineral Uptake, Fatemeh Sadeghi, Somayeh Esmaeili, Mehrangiz Chehrazi

Turkish Journal of Agriculture and Forestry

Salinity stress impairs plant growth, nutrient homeostasis, and metabolism, particularly in arid ecosystems. Phyla nodiflora, a ground cover used for erosion control, shows preliminary salinity tolerance, but the mechanistic basis of its long-term adaptation and the potential for enhancement via potassium humate (KH) were unknown. Plant growth, key biochemical attributes, and nutrient uptake were assessed to elucidate how KH modulates physiological performance under increasing salinity. In a 129-day greenhouse experiment, plants were exposed to five salinity levels (0 to 16 dS m⁻¹ NaCl) and three KH concentrations (0, 500, and 1000 mg L⁻¹). Severe salinity (16 dS m⁻¹) without KH …

In Re: Lipitor Antitrust Litigation

2026 Decisions

USDC for the District of New Jersey

Conservation As A Guise: Green Grabbing And The Acculturation Erasure In Rempang, Indonesia, Umi Ma'rufah, Bobi Bobi, Yogi Eka Sahputra, Muhammad Ishlahudin

Forest and Society

This study examines how the state enacts green grabbing through forestry legal instruments and how this process intersects with the existence and cultural acculturation of the Sungai Raya community. Previous studies on state-led green grabbing have predominantly emphasized economic, political, and ecological dimensions, often overlooking the socio-cultural dynamics of affected communities. Employing a qualitative narrative research approach, this study draws on in-depth interviews and literature review to reconstruct the life histories of community members. Using the Rempang Eco-City National Strategic Project as a case study, this research identifies the unilateral designation of Kawasan Hutan Taman Buru (the Hunting Park Forest …

Ancestors And Tiger From Elsewhere: Emerging Forms Of Human-Tiger Socio-Natural Relations In Cosmopolitical Frontiers Of Sumatra, Imam Ardhianto, Febri Sastiviani Putri Cantika, Matahari Jingga, Dimas Iqbal Romadhon

Forest and Society

How are the moral relations between communities and the Sumatran tiger (Panthera tigris sumatrae) being reconfigured as forests fragment and land-use change accelerates across Sumatra's conservation landscape? This article addresses that question ethnographically, drawing on forty semi-structured interviews conducted in Agam and Pasaman Regencies (West Sumatra) between April and June 2026 and interviews with Yayasan SINTAS Indonesia. The article documents the three animistic category of the tiger, comprising Datuk/ancestor, harimau jadi-jadian, and harimau tandang, and traces how it is being reshaped by habitat fragmentation, commodity-driven land expansion, generational interruption of customary authority, and state translocation …

Treaty Hierarchy And Legal Pluralism In Cross-Border Governance: Comparative Study Of Jordan And France, Rola Nael Salameh, Numan Ahmad Elkhatib, Rami Ali Daradkeh, Mohammad Sulieman Issa Alhelalat

Hasanuddin Law Review

This study addresses the constitutional ambiguity surrounding the hierarchical status and domestic application of international human rights treaties, particularly in legal systems where treaty incorporation lacks explicit constitutional regulation. Though earlier researches have discussed issues such as treaty incorporation and constitutionality, there has been little analysis of the comparative role played by courts in bridging the international and domestic legal systems. The study adopts a qualitative doctrinal and comparative legal methodology, analyzing constitutional provisions, legislative frameworks, and judicial decisions across Jordan, France, and selected Arab jurisdictions, including Egypt and Morocco. The findings reveal that France adopts a hierarchical model granting …

The Freedom Myth: How Ski Culture's Hidden Conformity Reveals The Unconscious Power Of Brand Belonging, Isabel R. Phillips

University Honors Theses

Purpose: Ski culture sells freedom and enforces conformity. This review asks what unconscious behavioral patterns hold that contradiction in place, and how brands capitalize on it to manufacture belonging.

Design/Methodology/Approach: A narrative literature review across consumer psychology, behavioral neuroscience, sociology, and ski industry research. No primary data were collected. Four accounts of consistency-seeking are synthesized into one framework, then applied to three ski industry cases at ascending scales and tested against a comparative case from Spanish football.

Findings: Belonging is a conditioned response, and conditioning requires a stable stimulus. Consistency is therefore the precondition of belonging rather than a constraint …

Conventions Employed In Dardosipcat Transcriptions, Enrique Rodríguez Sánchez, Robert E. Vann

DARDOSIPCAT Documentation

No abstract provided.

Burnout, Compassion Fatigue, Secondary Trauma, And Experiences With Death And Dying Among Organ And Tissue Recovery Professionals: A Hermeneutic Phenomenological Study, Shelby Andreasen

Walden Dissertations and Doctoral Studies

Professionals in organ and tissue recovery have complex job roles that affect the outcomes of patients who wait for a life-saving organ or a life-enhancing tissue graft. This profession had little research regarding burnout, compassion fatigue, and secondary trauma, as well as how consistent involvement with deceased patients affects these professionals and the outcomes of their cases. The purpose of this qualitative phenomenological study was to explore the lived experiences of 11 organ and tissue recovery professionals (OTRPs). Constructivist self-development theory was applied to understand OTRPs’ lived experiences of compassion fatigue, secondary trauma, and burnout, as well as the impact …

Usa V. William Manderville

2026 Decisions

USDC for the District of New Jersey

Histomorphological Changes In Human Septal Cartilage Stored In Different Preservation Solutions ​, Özlem Akkoca, Aki̇f Si̇nan Bi̇lgen, Harun Çoban, Fatma Aslan Yay, Zeynep Kaptan, Funda Balkiliç Akkaya, Rahmi̇ Kiliç, Sami̇ Engi̇n Muz

Turkish Journal of Medical Sciences

Background/aim: To assess the histopathological effects of three preservation solutions (70% ethanol, povidone-iodine, and ciprofloxacin) on human septal cartilage obtained during septoplasty and to compare their preservation characteristics for potential future graft applications. Optimal preservation of septal cartilage is clinically important because well-preserved grafts may reduce the need for secondary cartilage harvesting and the associated donor-site morbidity while facilitating reconstructive procedures during revision surgery.

Materials and methods: A total of 90 septal cartilage specimens obtained from 30 patients undergoing septoplasty were allocated to three preservation groups and stored in the designated preservation solutions at +4 °C. Samples were examined histologically …

Demographic And Clinical Characteristics Of Frequent Users Of Emergency Medical Services In Türkiye ​, Burak Bekgöz, İshak Şan

Turkish Journal of Medical Sciences

Background/aim: Overuse of emergency medical services (EMS), particularly unnecessary ambulance requests, places considerable strain on limited healthcare resources and can delay responses to urgent cases. The present study analyzes the demographic characteristics, diagnoses, urgency, and hospital transfer status of frequent users of EMS in Türkiye.

Materials and methods: Included in the study were 41,113 patients who requested EMS four or more times within a year (defined as frequent users for the purpose of the study), excluding interhospital transfers. Data were accessed from the Emergency Medical Services Automation System (ASOS) database, which contains details of patient demographics, diagnoses, triage codes, reasons …

Perioperative Effects Of The Quadratus Lumborum Block In Percutaneous Biliary Drainage: A Prospective Randomized Controlled Study ​, Seyyi̇d Furkan Kina, Can Ozan Yazar, Cem Koray Çataroğlu, Erdi̇ Tangobay, Sadik Ahmet Uyanik, Savaş Altinsoy, Reyhan Polat, Jüli̇de Ergi̇l

Turkish Journal of Medical Sciences

Background/aim: The aim of this study was to evaluate the effect of the quadratus lumborum block (QLB) on intraoperative opioid consumption in patients undergoing percutaneous biliary drainage (PBD).

Materials and methods: A total of 57 patients who met the inclusion criteria were randomized into two groups: the sedation group (Group 1, n = 26) and the sedation with QLB group (Group 2, n = 26). The groups were compared in terms of intraoperative anesthetic consumption, vital parameters, postanesthesia care unit (PACU) recovery times, postoperative visual analog scale (VAS) scores, postoperative analgesic consumption, and clinician and patient satisfaction. The study was …

Teachers’ Communicative Experiences Of Media And Information Literacy (Mil) In Peri-Urban Schools In The Southern Philippines: A Hermeneutic Phenomenological Analysis, Author Information Removed

JMLE Submissions Open for Review

Media and Information Literacy (MIL) has become increasingly important as education responds to an increasingly complex information environment, yet less is known about how teachers experience and make sense of teaching it, particularly in resource-constrained contexts. Guided by Gadamerian hermeneutic phenomenology, this study explored the lived communicative experiences of seven Senior High School teachers from five peri-urban public schools in the Southern Philippines. In-depth interviews revealed three interconnected, culturally situated meanings: pagsugakod (carrying on amid uncertainty), pagtagad (attentive responsibility), and pagkabalaka (ongoing concern). Together, these meanings show how teachers navigate limited preparation, respond to students’ lived circumstances, and teach within …

How Much Of The Sky Now? Visibility Of Women In American History Textbooks Over Time, Grace Martin, Emma Maroni, Roger Clark

Sociology Between the Gaps: Forgotten and Neglected Topics

No abstract provided.

Governing Conservation Beyond The Rules: Bureaucratic Discretion In Indonesia, Dedy Asriady, Muh. Ilham Nasir, Emban Ibnurusyd Mas'ud, Supratman Supratman, Syamsu Alam, Muhammad Alif K. Sahide

Hasanuddin Law Review

Conservation governance is frequently characterized as a rule-based system in which bureaucratic actors enforce standardized regulations to protect biodiversity. In practice, however, conservation policies are implemented within socially contested landscapes. Strict regulatory enforcement may generate conflict and undermine governance objectives. Although public administration research underscores the importance of bureaucratic discretion in policy implementation, limited attention has been paid to its influence on environmental governance in developing countries. This article investigates discretionary practices in Indonesian conservation area management using an ethnographic approach that incorporates interviews, field observations, and case studies across multiple sites. The findings demonstrate that discretion occupies a central, …

Effect Of Rangeland Quality On Rumen Development Of Angora (Mohair) Goat Kids And Bucks, Betül Zehra Sariçi̇çek

Turkish Journal of Veterinary & Animal Sciences

This study was conducted to determine the effect of rangeland quality on the rumen development of Angora goat kids and bucks. Twenty male singleton Angora goat kids with similar birth dates and birth weights were selected from each farm in an area with three different rangeland quality levels (good, medium, or poor) in Ankara Province. The kids were weaned at 60 days of age and then grazed completely on rangeland until slaughter. Rumen volumetric and papillary development of animals slaughtered at 4 and 7 months of age were determined. Empty rumen length, width, and weight were affected by rangeland quality …

Hard Palate Morphology In The Anatolian Water Buffalo (Bubalus Bubalis), Mehmet Can, Şükrü Hakan Atalgin, Mehmet Faruk Aydin, Soner Bekmezci̇

Turkish Journal of Veterinary & Animal Sciences

This study aimed to examine the morphological and histological features of the hard palate in the Anatolian water buffalo through light and scanning electron microscopy, complemented by gross and morphometric evaluations. Eight hard palates were used in the study. A total of eight Anatolian water buffalo heads from healthy adult female water buffaloes were collected immediately after slaughter from various slaughterhouses in Balıkesir, Türkiye. After analyzing and identifying the obtained hard palate samples, measurements were taken and documented through photography. The papilla incisiva, located in the middle of the caudal concave edge on the ventral surface of the pulvinus dentalis, …

Aras V. B-U Realty Corp.

All Decisions

On remittitur from the Court of Appeals, the Appellate Division First Department addressed the standard for the fraud exception to the four-year lookback rule for rent overcharge claims. The court held that both the common-law standard as refined by Burrows v. 75-25 153rd St. (2025) and the legislature's 2024 statutory 'totality of circumstances' standard for fraudulent deregulation must be applied together, reversing and remanding to Supreme Court.

Matter Of 382 8th Ave. Realty Corp. V. Nys Div. Of Hous. & Community Renewal

All Decisions

In this Article 78 proceeding, the landlord sought to annul DHCR's determination on a petition for administrative review (PAR), arguing that the building underwent substantial rehabilitation and therefore was not subject to rent stabilization. The Appellate Division, 1st Department affirmed the Supreme Court's dismissal of the proceeding and upheld DHCR's decision, finding that the owner failed to establish substantial rehabilitation. The court upheld the retroactive application of Operational Bulletin 95-2 (issued in 1995 regarding work performed between 1981 and 1984), finding it conformed to the guidelines set by the court. The court found insufficient proof that at least 11 of …

Advancing Beyond An Entry-Level Job, Paul Hill, Osei Vega-Sandoval

All Current Publications

Entry-level positions are a gateway into the workforce, yet advancing beyond an early-career role is necessary to broaden one’s professional experience and earn a higher salary. Whether following the traditional path of moving up within an organization or developing extensive expertise, there are a variety of career paths and concepts to consider. This fact sheet provides strategies and insights for advancing to higher-level positions within organizations.